ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3815 check: MH DKL KOG0659 Cell cycle control, cell division, chromosome partitioning Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7
r_klactV3815 check: MH DKL KOG0659 Replication, recombination and repair Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7
r_klactV3815 check: MH DKL KOG0659 Transcription Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3815 1324675 1323746 -310
(310 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 498 e-141
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 333 1e-91
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 308 5e-84
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 302 5e-82
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 290 2e-78
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 290 2e-78
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 280 2e-75
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 260 2e-69
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 237 1e-62
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 233 3e-61
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 230 2e-60
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 229 5e-60
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 225 6e-59
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 224 9e-59
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 2e-58
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 223 4e-58
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 4e-58
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 4e-58
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 4e-58
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 4e-58
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 223 4e-58
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 221 1e-57
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 220 2e-57
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 218 9e-57
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 218 1e-56
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 217 2e-56
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 217 2e-56
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 217 2e-56
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 216 3e-56
At5g64960 [D] KOG0600 Cdc2-related protein kinase 215 6e-56
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 215 7e-56
At5g10270 [D] KOG0600 Cdc2-related protein kinase 214 1e-55
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 214 1e-55
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 213 3e-55
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 211 1e-54
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 210 2e-54
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 210 2e-54
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 209 4e-54
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 209 5e-54
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 209 5e-54
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 208 9e-54
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 207 1e-53
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 206 5e-53
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 206 5e-53
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 204 2e-52
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 202 5e-52
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 202 7e-52
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 200 2e-51
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 197 2e-50
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 196 5e-50
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 196 5e-50
At1g74330 [D] KOG0600 Cdc2-related protein kinase 195 8e-50
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 194 1e-49
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 194 1e-49
YPR161c [D] KOG0600 Cdc2-related protein kinase 194 2e-49
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 193 2e-49
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 193 3e-49
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 192 7e-49
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 191 1e-48
At1g71530 [D] KOG0600 Cdc2-related protein kinase 191 1e-48
At1g33770 [D] KOG0600 Cdc2-related protein kinase 191 1e-48
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 191 1e-48
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 190 2e-48
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 190 3e-48
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 189 3e-48
At1g18670 [D] KOG0600 Cdc2-related protein kinase 189 6e-48
At1g53050 [D] KOG0600 Cdc2-related protein kinase 188 7e-48
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 188 1e-47
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 187 1e-47
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 187 2e-47
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 187 2e-47
At1g54610 [D] KOG0600 Cdc2-related protein kinase 186 5e-47
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 185 8e-47
CE26422 [D] KOG0600 Cdc2-related protein kinase 184 1e-46
At4g10010 [D] KOG0600 Cdc2-related protein kinase 184 1e-46
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 184 2e-46
At5g50860 [D] KOG0600 Cdc2-related protein kinase 183 2e-46
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 183 2e-46
At5g44290 [D] KOG0600 Cdc2-related protein kinase 183 3e-46
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 183 3e-46
At3g05050 [D] KOG0600 Cdc2-related protein kinase 181 9e-46
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 181 9e-46
At1g09600 [D] KOG0600 Cdc2-related protein kinase 181 1e-45
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 180 2e-45
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 180 3e-45
At4g22940 [D] KOG0600 Cdc2-related protein kinase 179 5e-45
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 179 5e-45
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 178 1e-44
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 177 2e-44
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 177 2e-44
At1g03740 [D] KOG0600 Cdc2-related protein kinase 177 2e-44
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 177 2e-44
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 176 3e-44
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 174 1e-43
At5g39420 [D] KOG0600 Cdc2-related protein kinase 174 2e-43
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 173 2e-43
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 172 4e-43
YKL139w [D] KOG0600 Cdc2-related protein kinase 172 6e-43
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 172 6e-43
CE29020 [T] KOG0660 Mitogen-activated protein kinase 171 9e-43
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 171 9e-43
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 171 9e-43
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 170 2e-42
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 170 3e-42
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 169 4e-42
At1g57700 [D] KOG0600 Cdc2-related protein kinase 169 5e-42
7296451 [D] KOG0600 Cdc2-related protein kinase 169 6e-42
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 168 1e-41
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 167 1e-41
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 167 1e-41
YBL016w [T] KOG0660 Mitogen-activated protein kinase 167 2e-41
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 167 2e-41
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 167 2e-41
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 166 4e-41
CE06762 [T] KOG0660 Mitogen-activated protein kinase 166 4e-41
7301110 [T] KOG0660 Mitogen-activated protein kinase 166 4e-41
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 165 7e-41
CE06686 [T] KOG0660 Mitogen-activated protein kinase 165 9e-41
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 164 2e-40
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 164 2e-40
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 164 2e-40
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 164 2e-40
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 163 3e-40
7298087 [T] KOG0660 Mitogen-activated protein kinase 163 3e-40
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 162 6e-40
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 162 6e-40
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 162 6e-40
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 162 8e-40
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 161 1e-39
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 161 1e-39
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 160 2e-39
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 160 3e-39
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 160 3e-39
CE24971 [T] KOG0660 Mitogen-activated protein kinase 160 3e-39
CE01583 [T] KOG0660 Mitogen-activated protein kinase 160 3e-39
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 159 4e-39
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 159 6e-39
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 159 6e-39
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 159 6e-39
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 158 1e-38
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 158 1e-38
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 157 1e-38
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 157 2e-38
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 156 4e-38
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 155 9e-38
YMR139w [G] KOG0658 Glycogen synthase kinase-3 154 1e-37
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 154 1e-37
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 154 2e-37
7291043 [T] KOG0660 Mitogen-activated protein kinase 154 2e-37
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 152 6e-37
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 152 8e-37
CE21401 [G] KOG0658 Glycogen synthase kinase-3 151 1e-36
YGR040w [T] KOG0660 Mitogen-activated protein kinase 150 2e-36
CE17062 [T] KOG0660 Mitogen-activated protein kinase 150 2e-36
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 150 2e-36
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 150 3e-36
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 149 5e-36
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 149 5e-36
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 149 5e-36
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 149 5e-36
YLR113w [T] KOG0660 Mitogen-activated protein kinase 149 7e-36
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 148 9e-36
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 148 9e-36
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 148 1e-35
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 148 1e-35
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 147 1e-35
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 147 1e-35
7290342 [G] KOG0658 Glycogen synthase kinase-3 147 1e-35
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 147 2e-35
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 147 2e-35
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 147 2e-35
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 147 2e-35
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 147 2e-35
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 146 3e-35
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 146 4e-35
CE08727 [G] KOG0658 Glycogen synthase kinase-3 145 6e-35
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 145 7e-35
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 144 2e-34
YHR030c [T] KOG0660 Mitogen-activated protein kinase 144 2e-34
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 144 2e-34
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 144 2e-34
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 142 5e-34
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 142 5e-34
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 142 6e-34
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 141 1e-33
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 140 2e-33
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 140 3e-33
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 139 5e-33
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 138 1e-32
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 138 1e-32
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 137 2e-32
YPR054w [T] KOG0660 Mitogen-activated protein kinase 137 3e-32
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 137 3e-32
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 137 3e-32
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 137 3e-32
YKL161c [T] KOG0660 Mitogen-activated protein kinase 134 1e-31
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 134 2e-31
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 134 2e-31
CE27220 [T] KOG0660 Mitogen-activated protein kinase 134 2e-31
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 132 8e-31
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 131 1e-30
CE29318 [T] KOG0660 Mitogen-activated protein kinase 130 3e-30
YDL079c [G] KOG0658 Glycogen synthase kinase-3 129 5e-30
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 129 5e-30
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 128 9e-30
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 127 2e-29
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 127 2e-29
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 127 2e-29
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 127 2e-29
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 126 3e-29
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 125 6e-29
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 125 6e-29
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 125 1e-28
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 125 1e-28
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 124 1e-28
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 124 1e-28
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 124 1e-28
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 124 2e-28
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 122 9e-28
YDR477w [T] KOG0583 Serine/threonine protein kinase 120 2e-27
CE20405 [G] KOG0658 Glycogen synthase kinase-3 119 6e-27
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 119 7e-27
CE01612 [G] KOG0658 Glycogen synthase kinase-3 117 2e-26
CE05377 [G] KOG0658 Glycogen synthase kinase-3 117 2e-26
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 115 1e-25
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 114 1e-25
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 114 2e-25
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 113 3e-25
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 112 7e-25
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 112 7e-25
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 111 1e-24
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 110 3e-24
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 110 3e-24
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 109 4e-24
At5g39440 [T] KOG0583 Serine/threonine protein kinase 109 6e-24
At2g38490 [T] KOG0583 Serine/threonine protein kinase 109 6e-24
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 109 6e-24
At5g35410 [T] KOG0583 Serine/threonine protein kinase 108 8e-24
YNL307c [G] KOG0658 Glycogen synthase kinase-3 107 2e-23
CE05866 [G] KOG0658 Glycogen synthase kinase-3 107 2e-23
At4g18700 [T] KOG0583 Serine/threonine protein kinase 107 2e-23
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 106 4e-23
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 106 4e-23
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 106 4e-23
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 106 5e-23
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 106 5e-23
CE24761 [D] KOG0580 Serine/threonine protein kinase 106 5e-23
At5g25110 [T] KOG0583 Serine/threonine protein kinase 106 5e-23
At2g25090 [T] KOG0583 Serine/threonine protein kinase 106 5e-23
At5g01820 [T] KOG0583 Serine/threonine protein kinase 105 6e-23
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 105 8e-23
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 105 8e-23
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 105 8e-23
At3g01090 [T] KOG0583 Serine/threonine protein kinase 105 8e-23
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 105 1e-22
At5g57630 [T] KOG0583 Serine/threonine protein kinase 105 1e-22
CE09532 [G] KOG0658 Glycogen synthase kinase-3 104 1e-22
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 104 2e-22
At4g24400 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
At3g29160 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
At1g30270 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
CE18454 [T] KOG4717 Serine/threonine protein kinase 103 2e-22
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 103 2e-22
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 103 3e-22
At5g45810 [T] KOG0583 Serine/threonine protein kinase 103 3e-22
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 103 3e-22
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 103 4e-22
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 103 4e-22
At5g01810 [T] KOG0583 Serine/threonine protein kinase 103 4e-22
7294217 [D] KOG0588 Serine/threonine protein kinase 103 4e-22
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 5e-22
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 102 5e-22
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 102 7e-22
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 102 9e-22
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 102 9e-22
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 102 9e-22
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 102 9e-22
CE28218 [D] KOG0588 Serine/threonine protein kinase 101 1e-21
At5g10930 [T] KOG0583 Serine/threonine protein kinase 101 1e-21
At3g20860 [R] KOG0589 Serine/threonine protein kinase 101 1e-21
7290249 [R] KOG0586 Serine/threonine protein kinase 101 1e-21
7290150 [T] KOG0583 Serine/threonine protein kinase 101 1e-21
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 101 2e-21
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 101 2e-21
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 101 2e-21
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 2e-21
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 101 2e-21
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 101 2e-21
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 101 2e-21
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 101 2e-21
CE28643 [T] KOG0583 Serine/threonine protein kinase 101 2e-21
CE07458 [T] KOG0583 Serine/threonine protein kinase 101 2e-21
YCL024w [T] KOG0583 Serine/threonine protein kinase 100 2e-21
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 2e-21
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 3e-21
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 100 3e-21
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 100 3e-21
At5g07070 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 100 4e-21
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 4e-21
7299438 [R] KOG0586 Serine/threonine protein kinase 100 4e-21
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 100 5e-21
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 100 5e-21
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 5e-21
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 100 5e-21
At2g26980 [T] KOG0583 Serine/threonine protein kinase 100 5e-21
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 100 5e-21
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 6e-21
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 6e-21
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 99 8e-21
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 99 8e-21
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 8e-21
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 99 8e-21
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 8e-21
At4g30960 [T] KOG0583 Serine/threonine protein kinase 99 8e-21
7302464 [R] KOG0586 Serine/threonine protein kinase 99 8e-21
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 99 8e-21
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At5g45820 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 99 1e-20
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 98 1e-20
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 98 1e-20
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 98 1e-20
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 98 1e-20
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 98 2e-20
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 98 2e-20
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 98 2e-20
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 98 2e-20
At5g58380 [T] KOG0583 Serine/threonine protein kinase 98 2e-20
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 97 2e-20
At4g32830 [D] KOG0580 Serine/threonine protein kinase 97 2e-20
7303211 [T] KOG4717 Serine/threonine protein kinase 97 2e-20
YDR507c [D] KOG0588 Serine/threonine protein kinase 97 3e-20
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 97 3e-20
CE00847 [T] KOG0583 Serine/threonine protein kinase 97 3e-20
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 97 4e-20
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 97 4e-20
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 4e-20
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 5e-20
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 96 5e-20
7298004 [G] KOG0658 Glycogen synthase kinase-3 96 5e-20
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 96 7e-20
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 7e-20
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 96 7e-20
At1g01140 [T] KOG0583 Serine/threonine protein kinase 96 7e-20
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 96 9e-20
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 96 9e-20
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 96 9e-20
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 96 9e-20
7299437 [R] KOG0586 Serine/threonine protein kinase 96 9e-20
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 95 1e-19
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 95 1e-19
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 95 1e-19
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 95 1e-19
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 1e-19
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 95 1e-19
At2g30360 [T] KOG0583 Serine/threonine protein kinase 95 1e-19
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 95 1e-19
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 94 2e-19
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 94 2e-19
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 94 2e-19
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 94 2e-19
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 2e-19
At2g25880 [D] KOG0580 Serine/threonine protein kinase 94 2e-19
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 2e-19
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 94 2e-19
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 94 3e-19
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 94 3e-19
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 94 3e-19
CE27768 [R] KOG0586 Serine/threonine protein kinase 94 3e-19
CE23838 [R] KOG0586 Serine/threonine protein kinase 94 3e-19
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 94 3e-19
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 94 3e-19
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 94 3e-19
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 94 3e-19
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 93 4e-19
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 93 4e-19
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 93 4e-19
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 93 6e-19
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 93 6e-19
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 93 6e-19
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 93 6e-19
At1g29230 [T] KOG0583 Serine/threonine protein kinase 93 6e-19
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 92 7e-19
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 92 7e-19
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 92 7e-19
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 7e-19
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 92 1e-18
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 92 1e-18
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 92 1e-18
YOL128c [G] KOG0658 Glycogen synthase kinase-3 92 1e-18
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 1e-18
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 92 1e-18
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 92 1e-18
SPAC1D4.06c [R] KOG0594 Protein kinase PCTAIRE and related kinases 91 2e-18
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 91 2e-18
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 91 2e-18
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 91 2e-18
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 91 2e-18
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 91 2e-18
At2g34180 [T] KOG0583 Serine/threonine protein kinase 91 2e-18
7302570 [R] KOG0586 Serine/threonine protein kinase 91 2e-18
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 91 3e-18
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 91 3e-18
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 91 3e-18
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 91 3e-18
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 91 3e-18
At3g17510 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 91 3e-18
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 91 3e-18
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 91 3e-18
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 90 4e-18
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 90 4e-18
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 90 4e-18
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 90 4e-18
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 90 4e-18
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 90 4e-18
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 90 5e-18
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 90 5e-18
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 90 5e-18
At2g45490 [D] KOG0580 Serine/threonine protein kinase 90 5e-18
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 90 5e-18
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 89 6e-18
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 89 6e-18
CE05274 [T] KOG0690 Serine/threonine protein kinase 89 6e-18
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 6e-18
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 6e-18
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 89 6e-18
YPL141c [T] KOG0583 Serine/threonine protein kinase 89 8e-18
At4g14580 [T] KOG0583 Serine/threonine protein kinase 89 8e-18
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 8e-18
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 89 8e-18
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 89 8e-18
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 89 1e-17
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 89 1e-17
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 89 1e-17
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 89 1e-17
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 88 1e-17
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 88 1e-17
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 88 1e-17
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 1e-17
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 1e-17
At1g48260 [T] KOG0583 Serine/threonine protein kinase 88 1e-17
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 88 2e-17
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 88 2e-17
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 88 2e-17
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 88 2e-17
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 88 2e-17
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 88 2e-17
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 88 2e-17
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 2e-17
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 88 2e-17
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 2e-17
At1g54510 [R] KOG0589 Serine/threonine protein kinase 88 2e-17
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 88 2e-17
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 88 2e-17
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 87 2e-17
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 87 2e-17
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 87 2e-17
YOR233w [T] KOG0583 Serine/threonine protein kinase 87 3e-17
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 87 3e-17
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 3e-17
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 3e-17
7293601 [T] KOG0577 Serine/threonine protein kinase 87 3e-17
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 87 3e-17
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 87 4e-17
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 87 4e-17
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 87 4e-17
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 87 4e-17
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 4e-17
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 87 4e-17
7300224 [T] KOG0201 Serine/threonine protein kinase 87 4e-17
YOR267c [D] KOG0590 Checkpoint kinase and related serine/threoni... 86 5e-17
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 86 5e-17
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 86 5e-17
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 86 5e-17
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 86 5e-17
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 86 5e-17
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 5e-17
7295638 [T] KOG0603 Ribosomal protein S6 kinase 86 5e-17
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 498 bits (1281), Expect = e-141
Identities = 232/297 (78%), Positives = 271/297 (91%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVN 68
+YTKEKK GEGTYAVVYLG + STGR IA+KEIKTS+FKDGLDMSA+REVK+LQE++H N
Sbjct: 6 EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPN 65
Query: 69 VIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFI 128
VIEL+D+FMA DNLNLVLEFLP DLE++IKD SI+F+PADIK+W+LMTLRGV+HCHRNFI
Sbjct: 66 VIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFI 125
Query: 129 LHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSA 188
LHRDLKPNNLL +PDGQ+K+ADFGLAR + +P EILTSNVVTRWYRAPELLFGAKHYTSA
Sbjct: 126 LHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSA 185
Query: 189 VDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYP 248
+DIWSVGVIFAELMLRIPYLPG++DVDQ+ VTFRALGTPTD DWPEVSSF YNK+QIYP
Sbjct: 186 IDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYP 245
Query: 249 PPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQDL 305
PPSR+ELR+RFIAA+E AL+ + GM+ MNP+KRW AV+CL+S YF+ELP P+ P +
Sbjct: 246 PPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSDPSSI 302
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 333 bits (855), Expect = 1e-91
Identities = 166/304 (54%), Positives = 215/304 (70%), Gaps = 2/304 (0%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQE 63
KS Y KE+K GEGTYAVV+LG +K T R +A+K+IK QFKDG+D+SALRE+KFL+E
Sbjct: 5 KSDKWTYVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRE 64
Query: 64 LKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
+H NVIELVDVF NLN++LEFL +DLE++IKD I+F PA IKSW++M LRG+HH
Sbjct: 65 SRHDNVIELVDVFSTKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHI 124
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H FILHRDLKPNNLL++ DG LK+ADFGL+R +P ++ V+TRWYR PEL G +
Sbjct: 125 HSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSH-MSHQVITRWYRPPELFMGCR 183
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y + VD+WSVG IFAELMLR PYLPG+ D+DQ+NV FRALGTP + NY +
Sbjct: 184 SYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVE 243
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQ 303
++ PPP+ + F AA ++L+ M+ NP +R A + L+ YF LP+PT P
Sbjct: 244 MKHIPPPN-GGMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPKPTHPS 302
Query: 304 DLPK 307
LP+
Sbjct: 303 LLPR 306
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 308 bits (790), Expect = 5e-84
Identities = 147/304 (48%), Positives = 209/304 (68%), Gaps = 3/304 (0%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQE 63
K D Y K++ G+GTY VV+ T T +++A+K+I+ + ++G++++ALRE+K L+E
Sbjct: 6 KKVADRYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKE 65
Query: 64 LKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
LKH ++I L+D F +NL+LV EF+ DLE +I+D++I SPADIKS++LMT +G+ +C
Sbjct: 66 LKHPHIILLIDAFPHKENLHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMTFKGLAYC 125
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H ++LHRD+KPNNLL+ DGQLK+ADFGLAR+ SP T V RWYRAPELLFGAK
Sbjct: 126 HDKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFGAK 185
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y +AVD+W+V IFAEL+LR P+L G D+DQ++ F A GTP WP+++ +Y +
Sbjct: 186 QYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDLTKLPDYVE 245
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQ 303
Q P PS LR F A +++AL+L+S M +PK R + L+ +YF P PT P
Sbjct: 246 YQFVPAPS---LRSLFPAVSDDALDLLSKMFTYDPKARISIKQALEHRYFTSAPAPTDPA 302
Query: 304 DLPK 307
LPK
Sbjct: 303 KLPK 306
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 302 bits (773), Expect = 5e-82
Identities = 142/304 (46%), Positives = 202/304 (65%), Gaps = 3/304 (0%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQE 63
K D Y K + G+GTY VV+ T G ++A+K+I+ + K+G++++ALRE+K L+E
Sbjct: 5 KKVADRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKE 64
Query: 64 LKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
LKH ++IEL+D F +NL++V EF+ DLE +I+D ++ SP D+KS++ M L+G+ +C
Sbjct: 65 LKHPHIIELIDAFPHKENLHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMILKGLEYC 124
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H ++LHRD+KPNNLL+ P+GQLK+ADFGLAR+ SP T V RWYRAPELLFGAK
Sbjct: 125 HGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFGAK 184
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y AVD+W+ G IFAEL+LR P+L G D+DQ++ F A GTP WP++ +Y +
Sbjct: 185 QYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVE 244
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQ 303
Q P PS LR +E+AL+L+S M +PK R + L+ +YF P PT P
Sbjct: 245 YQFVPAPS---LRSLLPTVSEDALDLLSKMFTYDPKSRISIQQALKHRYFTSAPSPTDPL 301
Query: 304 DLPK 307
LP+
Sbjct: 302 KLPR 305
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 290 bits (742), Expect = 2e-78
Identities = 137/299 (45%), Positives = 201/299 (66%), Gaps = 3/299 (1%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
VD Y + + GEGTY VVY T TG+++AVK+I+ K+G++ +ALRE+K L+EL H
Sbjct: 10 VDRYLRRQILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNH 69
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
+++EL+D F + +L+LV E++ DLE +I+D +I SP DIKS++LMTL+G+ +CH+
Sbjct: 70 PHIVELIDAFPHDGSLHLVFEYMQTDLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKK 129
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
++LHRD+KPNNLL+ +G LK+ADFGLARL SP T V WYRAPELLFG++ Y
Sbjct: 130 WVLHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSRQYG 189
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ VD+W+ G IFAEL+LR P+LPG ++DQ+ F+A GTP + W ++ +Y +
Sbjct: 190 AGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYMEFSY 249
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQDL 305
P P LR F A+++AL+L++ M I +P++R + L +YF P PT P L
Sbjct: 250 TPAP---PLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDHRYFSSSPSPTEPGKL 305
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 290 bits (741), Expect = 2e-78
Identities = 147/312 (47%), Positives = 206/312 (65%), Gaps = 6/312 (1%)
Query: 1 MTLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKT---SQFKDGLDMSALRE 57
+ +KS Y K GEG +A VY K+T + +A+K+IK S+ KDG++ +ALRE
Sbjct: 3 LDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALRE 62
Query: 58 VKFLQELKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTL 117
+K LQEL H N+I L+D F N++LV +F+ DLE+IIKD S++ +P+ IK+++LMTL
Sbjct: 63 IKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTL 122
Query: 118 RGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPE 177
+G+ + H+++ILHRDLKPNNLLL +G LK+ADFGLA+ SP T VVTRWYRAPE
Sbjct: 123 QGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS 237
LLFGA+ Y VD+W+VG I AEL+LR+P+LPG D+DQ+ F LGTPT+ WP++ S
Sbjct: 183 LLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCS 242
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
+Y + +P L F AA ++ L+LI G+ + NP R A + L+ +YF P
Sbjct: 243 LPDYVTFKSFP---GIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRP 299
Query: 298 EPTLPQDLPKLN 309
PT LP+ N
Sbjct: 300 GPTPGCQLPRPN 311
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 280 bits (716), Expect = 2e-75
Identities = 141/300 (47%), Positives = 196/300 (65%), Gaps = 6/300 (2%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQ---FKDGLDMSALREVKFLQELKH 66
Y K GEG +A VY T + +AVK+IK +DG++ +ALRE+K LQEL+H
Sbjct: 12 YAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQH 71
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N+I LVDVF N++LV +F+ DLE+IIKD I+ + A+IK++ +MTL+G+ + H N
Sbjct: 72 ENIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLN 131
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+ILHRDLKPNNLL+ DG LKI DFGLA+ SP I T +VVTRWYR+PELLFGA+ Y
Sbjct: 132 WILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYG 191
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ VD+W+VG I AELMLR+P++PG D+DQ+ F LGTPT+A+WP +S +Y + +
Sbjct: 192 TGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRN 251
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQDLP 306
+P + + F AA + + L+ + MNP +R + L YF P PT+ LP
Sbjct: 252 FPGTPLDNI---FTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPKLP 308
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 260 bits (664), Expect = 2e-69
Identities = 132/310 (42%), Positives = 199/310 (63%), Gaps = 19/310 (6%)
Query: 10 YTKEKKAGEGTYAVVYLGTKK--------STGRSI-----AVKEIKTSQFKDGLDMSALR 56
Y +E++ GEGTYAV+YLG + S+G I A+K+IK +++ G ++SA+R
Sbjct: 4 YIRERRLGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEISAIR 63
Query: 57 EVKFLQELKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMT 116
E+K L+ + V+ L+D F+ + +++VLE++ +LE +I+++ + P DIK+WILM
Sbjct: 64 EIKSLKRIDSKYVVRLIDTFVYDKCVHIVLEYVETNLENVIRNSDKIIMPGDIKAWILMV 123
Query: 117 LRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAP 176
LRGV+ CHR FI+HRD+KPNN+L+ +G +K+ADFGL R + + +T VTRWYRAP
Sbjct: 124 LRGVYECHRLFIIHRDIKPNNILITSEGMVKLADFGLTRGIGNR---MTPQAVTRWYRAP 180
Query: 177 ELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS 236
ELL G++ Y S VD+WSVG +FAEL LR+P G D+ Q+++ FRALGTP + +WP VS
Sbjct: 181 ELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTPVEREWPGVS 240
Query: 237 SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+ + Q YP S L F AA+ +AL+L+ ++ +NP R ++ YF+
Sbjct: 241 TLPEFLDFQQYPKAS---LNGLFSAASSDALDLLEKLLTLNPCNRISCDDAIKHPYFKSS 297
Query: 297 PEPTLPQDLP 306
P PT LP
Sbjct: 298 PPPTPIGKLP 307
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 237 bits (605), Expect = 1e-62
Identities = 122/292 (41%), Positives = 174/292 (58%), Gaps = 4/292 (1%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++DYTK +K GEGTY VVY G K+TG+ +A+K+I+ ++G+ +A+RE+ L+EL+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDT--SIMFSPADIKSWILMTLRGVHHCH 124
N++ L DV M + L L+ EFL DL+ + + +KS++ L+G+ CH
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKH 184
+LHRDLKP NLL+ G +K+ADFGLAR P + T VVT WYR+PE+L G+
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y++ VDIWS+G IFAEL + P G ++DQ+ FRALGTP + WPEV S +Y
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK-- 238
Query: 245 QIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+P L EN L+L+S M+I +P KR L YF +L
Sbjct: 239 NTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 290
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 233 bits (593), Expect = 3e-61
Identities = 119/294 (40%), Positives = 180/294 (60%), Gaps = 3/294 (1%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++++ K +K GEGTY VVY K TG +A+K+I+ +G+ +A+RE+ L+EL H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPAD-IKSWILMTLRGVHHCHR 125
N+++L+DV + L LV EFL DL+ + +++ P IKS++ L+G+ CH
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
+ +LHRDLKP NLL+ +G +K+ADFGLAR P T VVT WYRAPE+L G K+Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 186 TSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQ 245
++AVDIWS+G IFAE++ R PG ++DQ+ FR LGTP + WP V+S +Y
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYK--P 238
Query: 246 IYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+P +R++ + E+ L+S M+ +P KR A L +FQ++ +P
Sbjct: 239 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 292
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 230 bits (586), Expect = 2e-60
Identities = 118/303 (38%), Positives = 183/303 (59%), Gaps = 3/303 (0%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V ++ K + GEGTY +VY T +A+K+++ + KDG+ +S+LRE+ L L+
Sbjct: 35 SVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLR 94
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++EL +V + N +++ LV+ + DL ++++ FS A +K +L LRG+ +
Sbjct: 95 HPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYL 154
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
HRNFI+HRDLK +NLL+ G +K ADFGLAR P + +T VVT WYRAPELL G
Sbjct: 155 HRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTT 214
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
T+++D+W+VG I AEL+ P LPG ++ QI++ + LGTP++ WP S +
Sbjct: 215 TQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQ 274
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQ 303
+ P L+ +F +E L L+ + + +PKKR A CL+S YF+E P P P+
Sbjct: 275 YSLRKQP-YNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPE 333
Query: 304 DLP 306
+P
Sbjct: 334 LMP 336
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 229 bits (583), Expect = 5e-60
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 2/304 (0%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
+++DDY +K EG+Y +VY G KST +A+K+IK G +++LRE++ L +
Sbjct: 69 NSIDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSI 128
Query: 65 KHVNVIELVDVFMAND--NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHH 122
+H N++EL V + D ++ LV+EF+ DL+ ++ + F +++K+ +L L
Sbjct: 129 RHDNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAF 188
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H ++ LHRDLKP+NLL+ G++K+ADFGLAR ++ P+ LT VVT WYRAPELL GA
Sbjct: 189 MHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGA 248
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
Y +D+WS+G IFAE++ R P GK ++DQ+ F LG PT +WP+ N
Sbjct: 249 PSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYAN 308
Query: 243 KIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
KI+ P+ ++R T NA +L++ ++ +NP KR A + L+ YF E P P P
Sbjct: 309 KIKHPTVPTHSKIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYESPRPKDP 368
Query: 303 QDLP 306
+ P
Sbjct: 369 KFFP 372
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 225 bits (574), Expect = 6e-59
Identities = 119/305 (39%), Positives = 176/305 (57%), Gaps = 7/305 (2%)
Query: 3 LKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQ 62
+ + +D++ + +K GEGTY +VY STG+ +A+K+I+ +G+ +A+RE+ L+
Sbjct: 1 MTTILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLK 60
Query: 63 ELKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHH 122
LKH NV++L DV ++ +NL ++ E+L DL+ ++ +F+P IKS++ L V
Sbjct: 61 NLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGF 120
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
CH N ILHRDLKP NLL+ G++K+ADFGLAR P T VVT WYRAPE+L G
Sbjct: 121 CHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGT 180
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
K Y++ VDIWS+G IF+E+++R PG ++DQ+ FR L TP + +WP V+ ++
Sbjct: 181 KFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFK 240
Query: 243 KIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF---QELPEP 299
P E A ELI M+ +P R A LQ YF Q +
Sbjct: 241 T----KFPRWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHV 296
Query: 300 TLPQD 304
LP D
Sbjct: 297 ALPVD 301
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 224 bits (572), Expect = 9e-59
Identities = 115/294 (39%), Positives = 178/294 (60%), Gaps = 3/294 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V ++ K + GEGTY +VY T +A+K+++ + KDG+ +S+LRE+ L L+
Sbjct: 6 SVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLR 65
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++EL +V + N +++ LV+ + DL ++++ FS A +K +L LRG+ +
Sbjct: 66 HPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYL 125
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
HRNFI+HRDLK +NLL+ G +K ADFGLAR P + +T VVT WYRAPELL G
Sbjct: 126 HRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTT 185
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
T+++D+W+VG I AEL+ P LPG ++ QI++ + LGTP++ WP S +
Sbjct: 186 TQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQ 245
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
+ P L+ +F +E L L+ + + +PKKR A CL+S YF+E P
Sbjct: 246 YSLRKQP-YNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKP 298
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 78 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 137
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 138 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 197
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 198 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 257
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 258 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 317
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 318 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 376
Query: 303 QDLP 306
P
Sbjct: 377 SMFP 380
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 182/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+VD++ + EGTY VVY K T +A+K +K + +G +++LRE+ + + +
Sbjct: 414 SVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQ 473
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 474 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 533
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT+WYRAPELL GAK
Sbjct: 534 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 593
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PG ++DQIN F+ LGTP++ WP S K
Sbjct: 594 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 653
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A +E +L++ + P +R A L+ +YF+E P P P
Sbjct: 654 MTFSEHP-YNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 712
Query: 303 QDLP 306
P
Sbjct: 713 SMFP 716
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 182/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+VD++ + EGTY VVY K T +A+K +K + +G +++LRE+ + + +
Sbjct: 416 SVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQ 475
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 476 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 535
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT+WYRAPELL GAK
Sbjct: 536 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 595
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PG ++DQIN F+ LGTP++ WP S K
Sbjct: 596 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 655
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A +E +L++ + P +R A L+ +YF+E P P P
Sbjct: 656 MTFSEHP-YNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 714
Query: 303 QDLP 306
P
Sbjct: 715 SMFP 718
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 410 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 469
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 470 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 529
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 530 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 589
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 590 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 649
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 650 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 708
Query: 303 QDLP 306
P
Sbjct: 709 SMFP 712
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 419 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 478
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 479 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 598
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 659 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 717
Query: 303 QDLP 306
P
Sbjct: 718 SMFP 721
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 100 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 159
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 160 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 219
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 220 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 279
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 280 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 339
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 340 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 398
Query: 303 QDLP 306
P
Sbjct: 399 SMFP 402
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 204 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 263
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 264 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 323
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 324 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 383
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 384 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 443
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 444 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 502
Query: 303 QDLP 306
P
Sbjct: 503 SMFP 506
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 387 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 446
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 447 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 506
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 507 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 566
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 567 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 626
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 627 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 685
Query: 303 QDLP 306
P
Sbjct: 686 SMFP 689
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 376 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 435
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 436 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 495
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 496 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 555
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 556 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 615
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 616 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 674
Query: 303 QDLP 306
P
Sbjct: 675 SMFP 678
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 165 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 224
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 225 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 284
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 285 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 344
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 345 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 404
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 405 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 463
Query: 303 QDLP 306
P
Sbjct: 464 SMFP 467
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 421 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 480
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 481 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 540
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 541 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 600
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 601 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 661 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 719
Query: 303 QDLP 306
P
Sbjct: 720 SMFP 723
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 223 bits (569), Expect = 2e-58
Identities = 118/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 434 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 493
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 494 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 553
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 554 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 613
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PGK ++DQIN F+ LGTP++ WP S K
Sbjct: 614 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 673
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 674 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 732
Query: 303 QDLP 306
P
Sbjct: 733 SMFP 736
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 223 bits (567), Expect = 4e-58
Identities = 116/297 (39%), Positives = 174/297 (58%), Gaps = 10/297 (3%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK- 65
+++Y K +K GEGTY VVY K +GR +A+K+I+ +G+ +A+RE+ L+E+
Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60
Query: 66 ---HVNVIELVDVFMANDNLNLVLEFLPADL----EIIIKDTSIMFSPADIKSWILMTLR 118
N + L+D+ A L LV EFL DL + I + + P ++ + +
Sbjct: 61 ENNRSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVN 120
Query: 119 GVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
GV+ CH I+HRDLKP NLL+ +G LK+ADFGLAR P T +VT WYRAPE+
Sbjct: 121 GVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEV 180
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSF 238
L G++HY++ VDIWSVG IFAE++ R P PG ++D+I F+ LGTP + WP V+
Sbjct: 181 LLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPGVTLL 240
Query: 239 SNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+Y +P R +L + E+A+EL+S M++ +P R A + LQ Y ++
Sbjct: 241 QDYK--STFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQQNYLRD 295
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 223 bits (567), Expect = 4e-58
Identities = 117/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 416 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 475
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 476 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 535
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT+WYRAPELL GAK
Sbjct: 536 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 595
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PG ++DQIN F+ LGTP++ WP S K
Sbjct: 596 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 655
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 656 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 714
Query: 303 QDLP 306
P
Sbjct: 715 SMFP 718
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 223 bits (567), Expect = 4e-58
Identities = 117/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 419 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 478
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 479 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT+WYRAPELL GAK
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PG ++DQIN F+ LGTP++ WP S K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 659 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 717
Query: 303 QDLP 306
P
Sbjct: 718 SMFP 721
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 223 bits (567), Expect = 4e-58
Identities = 117/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 406 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 465
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 466 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 525
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT+WYRAPELL GAK
Sbjct: 526 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 585
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PG ++DQIN F+ LGTP++ WP S K
Sbjct: 586 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 645
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 646 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 704
Query: 303 QDLP 306
P
Sbjct: 705 SMFP 708
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 223 bits (567), Expect = 4e-58
Identities = 117/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 415 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 474
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 475 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 534
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT+WYRAPELL GAK
Sbjct: 535 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 594
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PG ++DQIN F+ LGTP++ WP S K
Sbjct: 595 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 654
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 655 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 713
Query: 303 QDLP 306
P
Sbjct: 714 SMFP 717
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 223 bits (567), Expect = 4e-58
Identities = 117/304 (38%), Positives = 183/304 (59%), Gaps = 4/304 (1%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ + + +
Sbjct: 36 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 95
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ + ++ + + D + +V+ ++ DL+ +++ F P ++K+ ++ LRGV H
Sbjct: 96 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 155
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + T VVT+WYRAPELL GAK
Sbjct: 156 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 215
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++AVD+WSVG IF EL+ + P PG ++DQIN F+ LGTP++ WP S K
Sbjct: 216 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 275
Query: 244 IQIYPPPSREELRRRFIA-ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
+ P LR+RF A ++ +L++ + P +R A L+ +YF+E P P P
Sbjct: 276 MTFSEHP-YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 334
Query: 303 QDLP 306
P
Sbjct: 335 SMFP 338
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 221 bits (562), Expect = 1e-57
Identities = 117/292 (40%), Positives = 175/292 (59%), Gaps = 4/292 (1%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
+D Y K +K GEGTY VVY K T +IA+K+I+ Q +G+ +A+RE+ L+E++H
Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPAD-IKSWILMTLRGVHHCHR 125
N+++ DV + L LV E+L DL+ + T IK+++ LRG+ +CH
Sbjct: 61 SNIVKYDDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHS 120
Query: 126 NFILHRDLKPNNLLL-APDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKH 184
+ +LHRDLKP NLL+ LK+ADFGLAR P T VVT WYRAPE+L G+ H
Sbjct: 121 HRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSHH 180
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y++ VDIWSVG IFAE++ + P PG ++DQ+ FR +GTP + W V+S +Y
Sbjct: 181 YSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYK-- 238
Query: 245 QIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+P +L + ++L+S M++M+P KR +A L+ +YF++L
Sbjct: 239 SAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEYFKDL 290
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 220 bits (560), Expect = 2e-57
Identities = 120/295 (40%), Positives = 172/295 (57%), Gaps = 4/295 (1%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
+D + K +K GEGTY VVY + TG+ +A+K+I+ +G+ +A+RE+ L+ELKH
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPAD-IKSWILMTLRGVHHCHR 125
N++ L+DV L LV EFL DL+ + T P IKS++ L+GV CH
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
+ ++HRDLKP NLL+ G +K+ADFGLAR P T VVT WYRAPE+L G+K Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 186 TSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQ 245
T+AVDIWS+G IFAE++ R PG ++DQ+ FR LGTP++ WP V+ +Y
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYK--G 238
Query: 246 IYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
+P +R+ L +L+ ++ +P +R A L YF PEP+
Sbjct: 239 SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPS 292
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 218 bits (555), Expect = 9e-57
Identities = 118/308 (38%), Positives = 176/308 (56%), Gaps = 15/308 (4%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
T++D+TK +K GEGTY VVY G + T +A+K+I+ +G+ +A+RE+ L+EL+
Sbjct: 18 TLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQ 77
Query: 66 HVNVIELVDVFMANDNLNLVLEFLPADLEIII----KDTSIMFSPADIKSWILMTLRGVH 121
H NV+ L V M + L L+ EFL DL+ + KD + +KS+ L+ +
Sbjct: 78 HPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLET--LKSYTFQILQAMC 135
Query: 122 HCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFG 181
CH+ ++HRDLKP NLL+ +G +K+ADFGLAR + P + T VVT WYRAPE+L G
Sbjct: 136 FCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMG 195
Query: 182 AKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNY 241
A+ Y+ VD+WS+G IFAE+ + P G ++D++ FR LGTPT+ +W V S +Y
Sbjct: 196 AQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDY 255
Query: 242 NKIQIYPPPSREELRRRFI-------AATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
+P LR +F + A L+ G++I +P R +A K L YF
Sbjct: 256 K--ATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFD 313
Query: 295 ELPEPTLP 302
+ LP
Sbjct: 314 NMDTSKLP 321
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 218 bits (554), Expect = 1e-56
Identities = 122/300 (40%), Positives = 171/300 (56%), Gaps = 27/300 (9%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTS---QFKDGLDMSALREVKFLQELKH 66
Y K GEG +A VYL +G +A+K+IK + KDG++ +A+RE+K L+E+ H
Sbjct: 5 YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHH 64
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N+I L DV ++ LV +F+ DLE +IKD I+ PA IK+ + L G+ H +
Sbjct: 65 DNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVH 124
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+ILHRDLKPNNLL+ G+ VVTRWYRAPELLFGA+ Y
Sbjct: 125 WILHRDLKPNNLLMNKMGR----------------------VVTRWYRAPELLFGARSYG 162
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+DIWSVG I AEL+LR P PG+ D+DQ+ F LG PT WP ++ ++Y + I
Sbjct: 163 VGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSY--VII 220
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQDLP 306
P L F AA ++ L+L++GM +P KR + LQ +YF+ P L ++LP
Sbjct: 221 KPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQPFCCLDEELP 280
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 217 bits (553), Expect = 2e-56
Identities = 115/293 (39%), Positives = 171/293 (58%), Gaps = 8/293 (2%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K +K GEGTYA VY G K T +A+KEI+ + ++G +A+REV L++LKH
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDLKH 247
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N++ L D+ + +L LV E+L DL+ + D + S ++K ++ LRG+ +CHR
Sbjct: 248 ANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRR 307
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+LHRDLKP NLL+ G+LK+ADFGLAR + P + ++ VVT WYR P++L G+ Y
Sbjct: 308 KVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYL 367
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS---FSNYNK 243
+ +D+W VG IF E+ P PG D++++ FR LGTP+ WP +SS F NYN
Sbjct: 368 TQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYN- 426
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+P E L +ELI + KKR A + ++ YF+ L
Sbjct: 427 ---FPKYKPEPLINHAPRLDSEGIELIRKFLQYESKKRVSAEEAMKHVYFRSL 476
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 217 bits (552), Expect = 2e-56
Identities = 113/309 (36%), Positives = 184/309 (58%), Gaps = 10/309 (3%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL-K 65
+D+Y + EGT+ VVY G K T +A+K +K + K+G ++ALRE+ L +
Sbjct: 353 IDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGN 412
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIM---FSPADIKSWILMTLRGV 120
H N++ + ++ + + D + + +EF+ D++ ++ S FS + K+ + L G+
Sbjct: 413 HPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGI 472
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
H H+ +ILHRDLK +NLL++ G LKIADFGLAR P + TS VVT WYR+PELL
Sbjct: 473 EHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLL 532
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
G + Y++ VD+WSVG I AE +L P PG+ +++QI F +GTPT++ WP V+
Sbjct: 533 GTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDG 592
Query: 241 YNKIQIYPPPSREELRRRFIAA---TENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
+ + P +LR+RF+A + +L++G++ ++PK R+ A + L ++F E P
Sbjct: 593 WKALTFEKYP-YNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTEEP 651
Query: 298 EPTLPQDLP 306
P P++ P
Sbjct: 652 YPVPPEEFP 660
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 217 bits (552), Expect = 2e-56
Identities = 113/289 (39%), Positives = 166/289 (57%), Gaps = 4/289 (1%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++D+ K +K GEGTY VVY G + TG+ +A+K+I+ +G+ +A+RE+ L+ELKH
Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSI--MFSPADIKSWILMTLRGVHHCH 124
N++ L DV M + + L+ EFL DL+ + + ++S++ + CH
Sbjct: 61 ENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCH 120
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKH 184
R +LHRDLKP NLL+ G +K+ADFGL R P I T +VT WYRAPE+L G+
Sbjct: 121 RRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPR 180
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y+ VDIWS+G IFAE+ R P G ++DQ+ FR L TPT+ WP V+S +Y
Sbjct: 181 YSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYK-- 238
Query: 245 QIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
+P S +L + N ++LI M+I +P R A L+ YF
Sbjct: 239 NTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 216 bits (550), Expect = 3e-56
Identities = 112/312 (35%), Positives = 190/312 (60%), Gaps = 14/312 (4%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+VD++ + K EGTY VVY K TG +A+K++K + ++G +++LRE+ L
Sbjct: 402 SVDEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFH 461
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H +++++ +V + + D++ +V+E++ DL+ +++ FS +++K +L L GV +
Sbjct: 462 HPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGVKYL 521
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H N++LHRDLK +NLLL G+LKI DFGLAR SP + T VVT WYRAPELL GAK
Sbjct: 522 HDNWVLHRDLKTSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAK 581
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++A+D+WS+G I AEL+++ P GK + DQ++ FR LGTP ++ WP FS
Sbjct: 582 QYSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWP---GFSKLPG 638
Query: 244 IQI-YPPPSREELRRRFIAA--------TENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
+++ + LR++F A ++ +L++ ++ +P++R + L+ +F+
Sbjct: 639 VKVNFVKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFR 698
Query: 295 ELPEPTLPQDLP 306
E+P P +P
Sbjct: 699 EVPLPKSKDFMP 710
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 215 bits (548), Expect = 6e-56
Identities = 121/320 (37%), Positives = 187/320 (57%), Gaps = 22/320 (6%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+VD + K ++ GEGTY VY+ + TG +A+K+I+ ++G ++A+RE+K L++L
Sbjct: 22 SVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLH 81
Query: 66 HVNVIELVDVFMAN----------DN------LNLVLEFLPADLEIIIKDTSIMFSPADI 109
H NVI L ++ + DN + +V E++ DL + + F+ I
Sbjct: 82 HENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQI 141
Query: 110 KSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE-ILTSNV 168
K ++ L G+H+CH N +LHRD+K +NLL+ +G LK+ADFGLAR + LT+ V
Sbjct: 142 KCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLTNRV 201
Query: 169 VTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPT 228
+T WYR PELL GA Y A+D+WSVG IFAEL+ P LPGK + +Q+N + G+P
Sbjct: 202 ITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPD 261
Query: 229 DADWPEVSSFSNYNKIQIYPPPSR--EELRRRFIAATENALELISGMMIMNPKKRWDAVK 286
+++WP VS YN+++ P R E+ R F +ALEL+ M++++P +R A
Sbjct: 262 ESNWPGVSKMPWYNQMKSSRPLKRRVREIYRHF---DRHALELLEKMLVLDPSQRICAKD 318
Query: 287 CLQSQYFQELPEPTLPQDLP 306
L ++YF P P P+ LP
Sbjct: 319 ALDAEYFWTDPLPCDPKSLP 338
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 215 bits (547), Expect = 7e-56
Identities = 113/291 (38%), Positives = 163/291 (55%), Gaps = 3/291 (1%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K +K GEGTY V+ + T +A+K ++ +G+ SALRE+ L+ELKH N+
Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
+ L DV ++ L LV EF DL+ + P +KS++ L+G+ CH +L
Sbjct: 64 VRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVL 123
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRDLKP NLL+ +G+LK+ADFGLAR P ++ VVT WYR P++LFGAK Y++++
Sbjct: 124 HRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSI 183
Query: 190 DIWSVGVIFAELM-LRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYP 248
D+WS G IFAEL P PG D DQ+ FR LGTPT+ WP ++ +Y +Y
Sbjct: 184 DMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMY- 242
Query: 249 PPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
P+ L +L+ ++ NP +R A + LQ YF + P
Sbjct: 243 -PATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 214 bits (546), Expect = 1e-55
Identities = 120/318 (37%), Positives = 184/318 (57%), Gaps = 18/318 (5%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+VD + K ++ GEGTY VY+ + TG +A+K+I+ ++G ++A+RE+K L++L
Sbjct: 22 SVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLH 81
Query: 66 HVNVIELVDVFMAN----------DN------LNLVLEFLPADLEIIIKDTSIMFSPADI 109
H NVI+L ++ + DN + +V E++ DL + + F+ I
Sbjct: 82 HENVIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQI 141
Query: 110 KSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE-ILTSNV 168
K ++ L G+H+CH N +LHRD+K +NLL+ +G LK+ADFGLAR + LT+ V
Sbjct: 142 KCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLTNRV 201
Query: 169 VTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPT 228
+T WYR PELL GA Y A+D+WSVG IFAEL+ P LPGK++ +Q+N F G+P
Sbjct: 202 ITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSPD 261
Query: 229 DADWPEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
+ WP VS +N + P R +R F +ALEL+ M++++P +R A L
Sbjct: 262 EKLWPGVSKMPWFNNFKPARPLKR-RVREFFRHFDRHALELLEKMLVLDPAQRISAKDAL 320
Query: 289 QSQYFQELPEPTLPQDLP 306
++YF P P P+ LP
Sbjct: 321 DAEYFWTDPLPCDPKSLP 338
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 214 bits (545), Expect = 1e-55
Identities = 115/288 (39%), Positives = 167/288 (57%), Gaps = 5/288 (1%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K +K GEGTY V+ G + T +A+K ++ + +G+ SALRE+ L+ELKH N+
Sbjct: 4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNI 63
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
+ L+DV ++ L LV E DL+ + A +S++L LRG+ CH + +L
Sbjct: 64 VRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVL 123
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRDLKP NLL+ +G+LK+ADFGLAR P + ++ VVT WYR P++LFGAK YT+++
Sbjct: 124 HRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSI 183
Query: 190 DIWSVGVIFAELM-LRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYP 248
D+WS G I AEL P PG D +DQ+ FR LGTP + WP VS S+Y + +P
Sbjct: 184 DMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFP 243
Query: 249 P-PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
S +L R +L+ ++I P +R A +Q YF +
Sbjct: 244 AITSWSQLVPRL---NSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 213 bits (542), Expect = 3e-55
Identities = 115/302 (38%), Positives = 175/302 (57%), Gaps = 15/302 (4%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
S+ + + +K G GTYA VY G K+TG +A+KE+K ++G +A+RE+ ++EL
Sbjct: 2 SSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKEL 60
Query: 65 KHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPAD-----IKSWILMTLRG 119
KH N++ L DV + L LV EF+ DL+ + ++ +P +K + L+G
Sbjct: 61 KHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQG 120
Query: 120 VHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELL 179
+ CH N ILHRDLKP NLL+ GQLK+ DFGLAR P +S VVT WYRAP++L
Sbjct: 121 LAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVL 180
Query: 180 FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
G++ Y++++DIWS G I AE++ P PG +D +Q+ + F +GTP ++ WP V+
Sbjct: 181 MGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLP 240
Query: 240 NYN-KIQIYPPPSREELRRRFIAATE-----NALELISGMMIMNPKKRWDAVKCLQSQYF 293
YN IQ PP +LR+ T+ N ++ + G++ +NP R A + L +F
Sbjct: 241 KYNPNIQQRPP---RDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF 297
Query: 294 QE 295
E
Sbjct: 298 AE 299
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 211 bits (536), Expect = 1e-54
Identities = 107/306 (34%), Positives = 179/306 (57%), Gaps = 10/306 (3%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
V ++ K + GEG+Y +VY + +A+K+++ Q KDGL +S LRE+ L++ H
Sbjct: 50 VSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHH 109
Query: 67 VNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
N++ L +V + D++ LV++F DL ++ + S F+ +++K L L+ + + H
Sbjct: 110 ENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLH 169
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKH 184
F++HRDLK +NLL+ G +K+ADFGLAR+ ++P + +T +VT WYRAPELL G +
Sbjct: 170 SRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRT 229
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
+T+AVD+W+ G I EL+L P LPG ++ Q+++ LG P+++ WP +
Sbjct: 230 HTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNF 289
Query: 245 QIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE------ 298
+ P L +F ++ L++ + I NPK R A +CL+S+YF + P+
Sbjct: 290 TLSQQP-YNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKYFVDPPQACDPGM 348
Query: 299 -PTLPQ 303
PT PQ
Sbjct: 349 MPTFPQ 354
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 210 bits (534), Expect = 2e-54
Identities = 112/290 (38%), Positives = 165/290 (56%), Gaps = 7/290 (2%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVN 68
+Y K +K GEGTY V+ K++G +A+K ++ +G+ SALRE+ L+ELKH N
Sbjct: 3 NYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRN 62
Query: 69 VIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFI 128
V+ L DV + + L LV E+ DL+ + +S +L LRG+ CH + +
Sbjct: 63 VVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHV 122
Query: 129 LHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSA 188
LHRDLKP NLL+ +G LK+ADFGLAR P ++ VVT WYR P++LFGAK Y ++
Sbjct: 123 LHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTS 182
Query: 189 VDIWSVGVIFAELM-LRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIY 247
+D+WS G IFAE+ P PG D DQ+ F+ LG+P++ +WP ++ +Y IY
Sbjct: 183 IDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPYPIY 242
Query: 248 PPPSREELRRRFIAATENA--LELISGMMIMNPKKRWDAVKCLQSQYFQE 295
P L I N+ +L+ +++ NP R DA L+ YF +
Sbjct: 243 HP----TLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFAD 288
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 210 bits (534), Expect = 2e-54
Identities = 116/316 (36%), Positives = 181/316 (56%), Gaps = 17/316 (5%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQ--FKD--GLDMSALREVKFL 61
+V+++ K K EGTY +VY + T +A+K+IK + F++ G +++LRE+ L
Sbjct: 293 SVNEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINIL 352
Query: 62 QELKHVNVIELVDVFMANDNLN---LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLR 118
H ++ + +V + N N +V+E L DL ++ FS +++K ++ L
Sbjct: 353 LSCNHPAIVNVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLMMQLLD 412
Query: 119 GVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
G+ + H N+I+HRDLKP+NLL+ G+LKI DFG+AR SP + T V+T+WYR PEL
Sbjct: 413 GLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSPIKPYTQMVITQWYRPPEL 472
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSF 238
L GAK Y++AVD+WSVG I AEL+ + P PGK ++DQ+ F LGTP +A WP SSF
Sbjct: 473 LLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWPGFSSF 532
Query: 239 SNYNKIQIYPPPSREELRRRFIA--------ATENALELISGMMIMNPKKRWDAVKCLQS 290
N +P LR++F A +E +L++ ++ ++P+KR L
Sbjct: 533 PNAK--AKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVEDALNH 590
Query: 291 QYFQELPEPTLPQDLP 306
+F E+P P +P
Sbjct: 591 GWFHEVPLPKSKDFMP 606
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 209 bits (532), Expect = 4e-54
Identities = 108/292 (36%), Positives = 170/292 (57%), Gaps = 2/292 (0%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K K GEGTYA V+ G K T +A+KEI+ + ++G +A+REV L+ LKH
Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKNLKH 197
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N++ L D+ + +L LV E+L +DL+ + + S ++K ++ LRG+ +CH
Sbjct: 198 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 257
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
ILHRDLKP NLL+ G+LK+ADFGLAR + P + ++ VVT WYR P++L G+ Y+
Sbjct: 258 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 317
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ +D+W VG I E+ P PG +++++ FR LGTPT+ WP V++FS + +
Sbjct: 318 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEF-RTYS 376
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE 298
+P + L + + L+S +++ K R A L YF+ L E
Sbjct: 377 FPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGE 428
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 209 bits (531), Expect = 5e-54
Identities = 110/295 (37%), Positives = 168/295 (56%), Gaps = 8/295 (2%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K K GEGTYA VY G K T +A+KEI+ + ++G +A+REV L++LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDLKH 220
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N++ L D+ +L LV E+L DL+ + D + + ++K ++ LRG+ +CHR
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 280
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+LHRDLKP NLL+ G+LK+ADFGLAR + P + ++ VVT WYR P++L G+ Y+
Sbjct: 281 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS---FSNYNK 243
+ +D+W VG IF E+ P PG +Q++ FR LGTPT+ WP + S F YN
Sbjct: 341 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 399
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE 298
YP E L + +L++ ++ + R A ++ +F L E
Sbjct: 400 ---YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGE 451
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 209 bits (531), Expect = 5e-54
Identities = 110/295 (37%), Positives = 168/295 (56%), Gaps = 8/295 (2%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K K GEGTYA VY G K T +A+KEI+ + ++G +A+REV L++LKH
Sbjct: 114 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDLKH 172
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N++ L D+ +L LV E+L DL+ + D + + ++K ++ LRG+ +CHR
Sbjct: 173 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 232
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+LHRDLKP NLL+ G+LK+ADFGLAR + P + ++ VVT WYR P++L G+ Y+
Sbjct: 233 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 292
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS---FSNYNK 243
+ +D+W VG IF E+ P PG +Q++ FR LGTPT+ WP + S F YN
Sbjct: 293 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 351
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE 298
YP E L + +L++ ++ + R A ++ +F L E
Sbjct: 352 ---YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGE 403
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 208 bits (529), Expect = 9e-54
Identities = 108/292 (36%), Positives = 171/292 (57%), Gaps = 5/292 (1%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K + GEG+YA VY G K T + +A+KEI+ + ++G +A+RE L+ELKH N+
Sbjct: 192 YVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQE-EEGAPFTAIREASLLKELKHSNI 250
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
+ L D+ + L V E++ DL ++ +++ ++ LRG+ +CH+ +L
Sbjct: 251 VTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVL 310
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRD+KP NLL++ G+LK+ADFGLAR + P + VVT WYR P++L G+ Y++++
Sbjct: 311 HRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSL 370
Query: 190 DIWSVGVIFAELMLRIPYLPG-KDDVDQINVTFRALGTPTDADWPEVSSFSNY--NKIQI 246
D+W VG IF E++ +P PG +D DQ++ F+ LGTPT+ WP V+ F Y +K+
Sbjct: 371 DMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGF 430
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE 298
Y P R E + +G + +NP++R A LQ YF +LP+
Sbjct: 431 YRPRKLGHNFPRLYDIIEGE-TIANGFLQLNPEQRLGADDALQHPYFAQLPK 481
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 207 bits (528), Expect = 1e-53
Identities = 116/314 (36%), Positives = 182/314 (57%), Gaps = 16/314 (5%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+V+++ + EGTY VVY K T +A+K +K + K+G +++LRE+ L + +
Sbjct: 554 SVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQ 613
Query: 66 HVNVIELVDVFMAN--DNLNLVLEFLPADLEIII---KDTSIMFSPADIKSWILMTLRGV 120
H N++ + ++ + + D + +V++++ DL+ ++ K+ F P ++K LR V
Sbjct: 614 HPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAV 673
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
H H N+ILHRDLK +NLLL+ G LK+ DFGLAR SP + TS VVT WYRAPELL
Sbjct: 674 AHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLL 733
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS--- 237
+ Y++ +D+WSVG IFAE + +P PGK ++D++N F+ LGTP + WP +
Sbjct: 734 CSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPA 793
Query: 238 ----FSNYNKIQIYPPPSREELRRRFIAAT-ENALELISGMMIMNPKKRWDAVKCLQSQY 292
S ++ YP +LR+ F T E L L+ G++ +PK+R A L+ +
Sbjct: 794 VKNMLSQNSQFTEYPV---SQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGF 850
Query: 293 FQELPEPTLPQDLP 306
F+ELP P P P
Sbjct: 851 FKELPLPIDPSMFP 864
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 206 bits (523), Expect = 5e-53
Identities = 109/293 (37%), Positives = 172/293 (58%), Gaps = 5/293 (1%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D Y K +K GEG+YA VY G K G+ +A+K I+ + ++G +A+RE L+ LKH
Sbjct: 115 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQE-EEGTPFTAIREASLLKGLKHA 173
Query: 68 NVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNF 127
N++ L D+ + L LV E++ DL + P ++K ++ LRG+ + H+ +
Sbjct: 174 NIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRY 233
Query: 128 ILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTS 187
ILHRDLKP NLL++ G+LK+ADFGLAR + P ++ VVT WYR P++L G+ Y++
Sbjct: 234 ILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYST 293
Query: 188 AVDIWSVGVIFAELMLRIPYLPGKDDV-DQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+D+W VG IF E++ + PG D+ DQ+ F LGTP + WP V S ++ K +
Sbjct: 294 CLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHF-KPER 352
Query: 247 YPPPSREELRRRF--IAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
+ S + LR+ + ++ +A +L S ++ +PK R A L +YF +LP
Sbjct: 353 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 405
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 206 bits (523), Expect = 5e-53
Identities = 105/294 (35%), Positives = 165/294 (55%), Gaps = 8/294 (2%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
+ + K +K GEGTY VVY +++T R +A+K+I+ +G+ + +RE+ L+ LKH
Sbjct: 3 ESFQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHS 62
Query: 68 NVIELVDVFMANDNLNLVLEFLPADLEIII---KDTSIMFSPADIKSWILMTLRGVHHCH 124
++EL DV N+ + LV E++ DL + D + ++ L + +CH
Sbjct: 63 TIVELSDVIYNNNKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAMEYCH 122
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKH 184
I HRDLKP N+L+ P +K+ADFGL R P T+ VVT WYR PELL G K+
Sbjct: 123 SRNIFHRDLKPQNILVDPKENIKLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGCKY 182
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN-K 243
Y ++VD+WS I AE++L P+ PG ++DQ+ F+ LGTP ++ W V +F NY +
Sbjct: 183 YDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVENFPNYKVE 242
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
++ P + + R + ++LIS M+ +PK R A L +YF+ +P
Sbjct: 243 FPVWDPVDLKTIFR----GDPDFVDLISKMLEYDPKMRMTAKNGLSHKYFEGMP 292
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 204 bits (518), Expect = 2e-52
Identities = 113/305 (37%), Positives = 160/305 (52%), Gaps = 9/305 (2%)
Query: 1 MTLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKF 60
+T + D Y + K GEG+YA VY K G +A+KEIK QF++GL +A+RE
Sbjct: 99 VTPQDVNDLYKRIDKLGEGSYATVYKCESKLDGSIVALKEIKL-QFQEGLPFTAIREASL 157
Query: 61 LQELKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGV 120
L+ L+H N++ L D+F + L V E++ DL ++ DIK + LRG+
Sbjct: 158 LRNLRHANIVSLHDIFYQHHQLTFVFEYMKMDLSKYLEQNVYGLDSIDIKLLLFQLLRGL 217
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
CHR ILHRDLKP NLLL DG LK+ADFGLAR + P + VVT WYR P++L
Sbjct: 218 DFCHRKKILHRDLKPQNLLLDEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLM 277
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDD------VDQINVTFRALGTPTDADWPE 234
G+ Y++++D+W VG IFAE+ PG D DQ+++ F GTP + WPE
Sbjct: 278 GSTDYSTSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGTPDEKKWPE 337
Query: 235 VSSFSNYNK--IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
V + Y Y S + F + EL+ ++ + P+ R A + Y
Sbjct: 338 VKTLPGYTPELFPRYRELSFIAVNPMFTKILKTGQELLGMLLQLRPESRVSAASAMLHPY 397
Query: 293 FQELP 297
F P
Sbjct: 398 FASFP 402
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 202 bits (514), Expect = 5e-52
Identities = 107/287 (37%), Positives = 164/287 (56%), Gaps = 5/287 (1%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVN 68
+Y + +K GEGTYA VY G + TG +A+K I+ +G +A+RE+ ++EL+H N
Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDA-DEGTPSTAIREISLMKELRHPN 60
Query: 69 VIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIM--FSPADIKSWILMTLRGVHHCHRN 126
++ L DV + L LV E++ DL+ + P+ +K++ L+G+ CH N
Sbjct: 61 IMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHEN 120
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+LHRDLKP NLL+ G+LK+ADFGLAR + P ++ VVT WYRAP++L G++ Y+
Sbjct: 121 RVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYS 180
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+++DIWSVG I AE+ P G ++ DQ+ FR LGTPT+ WP +S Y
Sbjct: 181 TSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYK--PT 238
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
+P ++L F L+L+ M+ + P+ R LQ +F
Sbjct: 239 FPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAWF 285
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 202 bits (513), Expect = 7e-52
Identities = 116/309 (37%), Positives = 173/309 (55%), Gaps = 22/309 (7%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K +K GEGTY VY +K+TG+ +A+K+ + ++G+ +ALRE+ LQ L
Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQ 60
Query: 67 ----VNVIELVDVFMAND---------NLNLVLEFLPADLEIIIKDTSIMFSPADIKS-- 111
V ++ + V + D NL LV E+L DL+ I +P +++
Sbjct: 61 SIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEASL 120
Query: 112 ---WILMTLRGVHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSN 167
++ +GV HCH + +LHRDLKP NLLL D G LKIAD GL+R P + T
Sbjct: 121 VQRFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTHE 180
Query: 168 VVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTP 227
+VT WYRAPE+L G+ HY++AVDIWSVG IFAE++ R PG + Q+ FR LGTP
Sbjct: 181 IVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTP 240
Query: 228 TDADWPEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKC 287
T+ WP V + +++ +YP ++L R + + ++L++ M+ NP +R A
Sbjct: 241 TEQQWPGVMALRDWH---VYPKWEPQDLSRAVPSLSPEGIDLLTQMLKYNPAERISAKAA 297
Query: 288 LQSQYFQEL 296
L YF L
Sbjct: 298 LDHPYFDSL 306
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 200 bits (508), Expect = 2e-51
Identities = 115/296 (38%), Positives = 169/296 (56%), Gaps = 14/296 (4%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTG---RSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+Y + +K GEGTY VVY G R +A+K+I+ +G+ +A+RE+ L+ELK
Sbjct: 7 NYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELK 66
Query: 66 HVNVIELVDVFMANDN-LNLVLEFLPADL----EIIIKDTSIMFSPADI-KSWILMTLRG 119
N++ L D+ ++ + L LV EFL DL E I KD + ADI K +++ +G
Sbjct: 67 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPL---GADIVKKFMMQLCKG 123
Query: 120 VHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELL 179
+ +CH + ILHRDLKP NLL+ DG LK+ DFGLAR P T +VT WYRAPE+L
Sbjct: 124 IAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 183
Query: 180 FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
G K Y++ VD WS+G IFAE+ R P G ++DQI FR LGTP +A WP++
Sbjct: 184 LGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLP 243
Query: 240 NYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
++ +P R++L + + ++L+ ++ +P R A + YFQE
Sbjct: 244 DFK--PSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQE 297
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 197 bits (501), Expect = 2e-50
Identities = 114/307 (37%), Positives = 171/307 (55%), Gaps = 20/307 (6%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK- 65
++ Y K +K GEGTY VY +K TG+ +A+K+ + ++G+ +ALRE+ LQ L
Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLST 60
Query: 66 HVNVIELVDVFMAND----------NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILM 115
+ V+ L+ V + NL LV E+L DL+ I +P ++ +++
Sbjct: 61 SIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQ 120
Query: 116 TL-----RGVHHCHRNFILHRDLKPNNLLLAPDGQL-KIADFGLARLMASPQEILTSNVV 169
L +GV HCH + +LHRDLKP NLLL D +L KIAD GL R P + T +V
Sbjct: 121 KLMFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTVPLKSYTHEIV 180
Query: 170 TRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTD 229
T WYRAPE+L G+ HY++ VD+WSVG IFAE++ R PG + Q+ FR LGTPT+
Sbjct: 181 TLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTE 240
Query: 230 ADWPEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQ 289
WP VS+ +++ +YP ++L + + ++L++ M+ NP +R A L
Sbjct: 241 QQWPGVSTLRDWH---VYPKWEPQDLTLAVPSLSPQGVDLLTKMLKYNPAERISAKTALD 297
Query: 290 SQYFQEL 296
YF L
Sbjct: 298 HPYFDSL 304
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 196 bits (497), Expect = 5e-50
Identities = 107/315 (33%), Positives = 174/315 (54%), Gaps = 13/315 (4%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQE 63
K VD + GEGTY VY K TG +A+K+++ K+G ++A+RE+K L++
Sbjct: 699 KLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQ 758
Query: 64 LKHVNVIELVDVFMANDN----------LNLVLEFLPADLEIIIKDTSIMFSPADIKSWI 113
L H ++I + ++ ++ LV E++ DL +++ + F+ IKS++
Sbjct: 759 LTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFM 818
Query: 114 LMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRW 172
+ G+ +CH+ LHRD+K +N+LL GQ+K+ADFGLARL +S + T+ V+T W
Sbjct: 819 RQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLW 878
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YR PELL G + YT A+D+WS G I EL + P ++ Q+ + R G+P A W
Sbjct: 879 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVW 938
Query: 233 PEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
P+V +N ++ R +LR F+ AL+L M+ ++P KR A + LQ ++
Sbjct: 939 PDVIKLPYFNTMK-PKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEF 997
Query: 293 FQEL-PEPTLPQDLP 306
+++ P P DLP
Sbjct: 998 LRDVEPSKMPPPDLP 1012
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 196 bits (497), Expect = 5e-50
Identities = 107/315 (33%), Positives = 174/315 (54%), Gaps = 13/315 (4%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQE 63
K VD + GEGTY VY K TG +A+K+++ K+G ++A+RE+K L++
Sbjct: 699 KLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQ 758
Query: 64 LKHVNVIELVDVFMANDN----------LNLVLEFLPADLEIIIKDTSIMFSPADIKSWI 113
L H ++I + ++ ++ LV E++ DL +++ + F+ IKS++
Sbjct: 759 LTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFM 818
Query: 114 LMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRW 172
+ G+ +CH+ LHRD+K +N+LL GQ+K+ADFGLARL +S + T+ V+T W
Sbjct: 819 RQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLW 878
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YR PELL G + YT A+D+WS G I EL + P ++ Q+ + R G+P A W
Sbjct: 879 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVW 938
Query: 233 PEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
P+V +N ++ R +LR F+ AL+L M+ ++P KR A + LQ ++
Sbjct: 939 PDVIKLPYFNTMK-PKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEF 997
Query: 293 FQEL-PEPTLPQDLP 306
+++ P P DLP
Sbjct: 998 LRDVEPSKMPPPDLP 1012
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 195 bits (495), Expect = 8e-50
Identities = 111/306 (36%), Positives = 171/306 (55%), Gaps = 11/306 (3%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D + K +K G+GTY+ V+ + TGR +A+K+++ F+ RE+ L+ L H
Sbjct: 119 DAFEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILRRLNHP 178
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
N+I+L + + + N+ LV E++ DL ++ I F+ IK ++ L G+ HCH
Sbjct: 179 NIIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCYMKQLLSGLDHCHS 238
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASP---QEILTSNVVTRWYRAPELLFGA 182
++HRD+K +NLLL+ +G LK+ADFGLA S ++ LTS VVT WYR PELL GA
Sbjct: 239 RGVMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTSRVVTLWYRPPELLLGA 298
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
Y ++VD+WSVG +FAEL+L P L G+ +V+Q++ F+ G+P + W + S
Sbjct: 299 TDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDYWKK----SKLP 354
Query: 243 KIQIYPPPSREE--LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
++ P + LR +E + LI ++ ++P KR A L SQYF P
Sbjct: 355 HAMLFKPQQTYDSCLRETLKDLSETEINLIETLLSIDPHKRGTASSALVSQYFTTKPFAC 414
Query: 301 LPQDLP 306
P LP
Sbjct: 415 DPSSLP 420
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 194 bits (493), Expect = 1e-49
Identities = 106/297 (35%), Positives = 164/297 (54%), Gaps = 12/297 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K + GEGTY VY TG +A+K I+ Q KDG ++ +REVK LQ L+H N+
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNI 336
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
+ L+++ + ++ +V E++ DL ++ ++ + F+P +IK + + H +L
Sbjct: 337 VRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGVL 396
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFGAKHYTSA 188
HRD+K +N+LL +G LK ADFGLAR S + T+ V+T W+R PELL G Y +A
Sbjct: 397 HRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDTA 456
Query: 189 VDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYP 248
VDIWS G I EL P+ G+D++ Q+ V + +GTP WPEV + Y ++
Sbjct: 457 VDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVKNLPWYELLK--- 513
Query: 249 PPSREELRRRFIAATEN-----ALELISGMMIMNPKKRWDAVKCLQSQYF-QELPEP 299
EE + RF+ + A++L ++ +NP R A + L +YF E P P
Sbjct: 514 --PVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTSESPPP 568
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 194 bits (493), Expect = 1e-49
Identities = 107/314 (34%), Positives = 174/314 (55%), Gaps = 15/314 (4%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL-K 65
+ +Y EGTY V+ G T +A+K K + K+G ++ALRE+ L +
Sbjct: 396 ISEYVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGA 455
Query: 66 HVNVIELVDVFMANDNLN--LVLEFLPADLEIII---KDTSIMFSPADIKSWILMTLRGV 120
H N++ + ++ + + + +E++ D++ +I + + F K+ + L G+
Sbjct: 456 HENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGI 515
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-----LTSNVVTRWYRA 175
H H+ +ILHRDLK +NLL++ G LKIADFGLAR ++I LT VVT WYR+
Sbjct: 516 EHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRS 575
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEV 235
PELL K Y++ VD+WS+G I AE ++ P G + +Q++ F+ +GTPT+ WP++
Sbjct: 576 PELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDI 635
Query: 236 SSFSNYNKIQIYPPPSREELRRRFIA---ATENALELISGMMIMNPKKRWDAVKCLQSQY 292
+N ++ +PP +LRR F E +L++GM+ +NP R A + LQ +
Sbjct: 636 KELKVWNMVE-FPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDW 694
Query: 293 FQELPEPTLPQDLP 306
F E P+ P+DLP
Sbjct: 695 FSEHPKAVPPEDLP 708
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 194 bits (492), Expect = 2e-49
Identities = 117/323 (36%), Positives = 174/323 (53%), Gaps = 29/323 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y +++K G+GT+ VY G T R +A+K+I S KD ++A RE+ L+ L H N+
Sbjct: 60 YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNI 119
Query: 70 IELVDVFM---------ANDNLN----LVLEFLPADLEIIIKDTSIMFSPADIKSWILMT 116
I+L+++ A+ NL+ ++L ++ ADL ++ + I DIK+ +L
Sbjct: 120 IKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQI 179
Query: 117 LRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLM------------ASPQEIL 164
L G+++ H +HRD+K N+L+ +G LK+ADFGLARL A
Sbjct: 180 LEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKY 239
Query: 165 TSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRAL 224
TS VVTRWYRAPEL+ G K YT+AVDIW VG +FAE + P L GK D+DQ +V F+ L
Sbjct: 240 TSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLL 299
Query: 225 GTPTDADWPEVSSFSNYNKIQI-YPPPSREELRRRFIAATENALELISGMMIMNPKKRWD 283
GTPT+ DW Y P RE + +E L+ + ++ ++P KR
Sbjct: 300 GTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYL---SETGLDFLGQLLALDPYKRLT 356
Query: 284 AVKCLQSQYFQELPEPTLPQDLP 306
A+ +F+E P P+ LP
Sbjct: 357 AMSAKHHPWFKEDPLPSEKITLP 379
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 193 bits (491), Expect = 2e-49
Identities = 113/304 (37%), Positives = 170/304 (55%), Gaps = 13/304 (4%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
S +D + K +K GEGTY VY +K+TG+ +A+K+ + + ++G+ + LRE+ L+ L
Sbjct: 9 SAMDAFEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRML 68
Query: 65 -KHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKD---TSIMFSPADIKSWILM 115
+ +V+ L+DV L LV E++ D++ I+ T IKS +
Sbjct: 69 ARDPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSFRSTGKNIPTQTIKSLMYQ 128
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRWYR 174
+G+ CH + ILHRDLKP+NLL+ P +LKIAD GLAR P + T ++T WYR
Sbjct: 129 LCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTLPMKKYTHEILTLWYR 188
Query: 175 APELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE 234
APE+L GA HY++AVD+WSVG IFAEL+ G ++ Q+ F+ GTP + WP
Sbjct: 189 APEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMWPG 248
Query: 235 VSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
VS+ N+++ YP L E ++L+S M+ P KR A ++ YF
Sbjct: 249 VSTLKNWHE---YPQWKPSTLSSAVPNLDEAGVDLLSKMLQYEPAKRISAKMAMEHPYFD 305
Query: 295 ELPE 298
+LPE
Sbjct: 306 DLPE 309
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 193 bits (490), Expect = 3e-49
Identities = 106/291 (36%), Positives = 160/291 (54%), Gaps = 5/291 (1%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y +K GEG+YA VY G + G+ +A+K I + ++G+ +A+RE L+ LKH N+
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNA-EEGVPFTAIREASLLKGLKHANI 110
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
+ L D+ + L V E++ DL + P +++ ++ LRG+ + H +L
Sbjct: 111 VLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVL 170
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRDLKP NLL++ G+LK+ADFGLAR + P + +S VVT WYR P+ L GA Y+S +
Sbjct: 171 HRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSEL 230
Query: 190 DIWSVGVIFAELMLRIPYLPGKDDV-DQINVTFRALGTPTDADWPEVSSFSNYNKIQIYP 248
DIW G IF E+ P PG ++ +Q+ + LG PT+ WP VS NYN + +P
Sbjct: 231 DIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNP-EWFP 289
Query: 249 PPSREELRRRF--IAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
P+ L + + A +L S M+ P+ R A + L YF LP
Sbjct: 290 LPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALP 340
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 192 bits (487), Expect = 7e-49
Identities = 110/322 (34%), Positives = 166/322 (51%), Gaps = 22/322 (6%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
S + DY +K GEGT+ VY ++ G+ A+K I K+G ++A+RE+K L+ +
Sbjct: 31 SHLTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSI 90
Query: 65 KHVNVIELVDVFMAN--------DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMT 116
KH N+I L D+ + ++ +V ++ DL ++++ S+ F+ IK ++
Sbjct: 91 KHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQL 150
Query: 117 LRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASP-------------QEI 163
G + H ILHRDLK NLL+ G LKIADFGLAR++ +
Sbjct: 151 FAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRRE 210
Query: 164 LTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRA 223
T VVTRWYR+PELL G + YT+A+D+WSVG I AE+ P L G D+DQ++ FR
Sbjct: 211 YTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRL 270
Query: 224 LGTPTDADWPEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWD 283
G+PT A P ++ +P R L F + L ++ +NP +R
Sbjct: 271 CGSPTQATMPNWEKLPGCEGVRSFPSHPR-TLETAFFTFGKEMTSLCGAILTLNPDERLS 329
Query: 284 AVKCLQSQYFQELPEPTLPQDL 305
A L+ +YF P P P +L
Sbjct: 330 ASMALEHEYFTTPPYPANPSEL 351
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 191 bits (485), Expect = 1e-48
Identities = 108/315 (34%), Positives = 170/315 (53%), Gaps = 13/315 (4%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQE 63
K VD + GEGTY VY K TG +A+K+++ K+G ++A+RE+K L++
Sbjct: 721 KRCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ 780
Query: 64 LKHVNVIELVDVFMANDN----------LNLVLEFLPADLEIIIKDTSIMFSPADIKSWI 113
L H +V+ + ++ + LV E++ DL +++ + FS IKS++
Sbjct: 781 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM 840
Query: 114 LMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRW 172
+ G+ +CH+ LHRD+K +N+LL GQ+K+ADFGLARL S + T+ V+T W
Sbjct: 841 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW 900
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YR PELL G + YT A+D+WS G I EL + P ++ Q+ + R G+P A W
Sbjct: 901 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW 960
Query: 233 PEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
P+V +N ++ R LR F AL+L+ M+ ++P KR A + LQS +
Sbjct: 961 PDVIKLPYFNTMK-PKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDF 1019
Query: 293 FQELP-EPTLPQDLP 306
+++ P DLP
Sbjct: 1020 LKDVELSKMAPPDLP 1034
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 191 bits (485), Expect = 1e-48
Identities = 111/308 (36%), Positives = 168/308 (54%), Gaps = 15/308 (4%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
+ + K K G+GTY+ VY TG+ +A+K+++ RE+ L++L H
Sbjct: 145 ESFEKLDKIGQGTYSSVYKARDLETGKIVAMKKVRFVNMDPESVRFMAREILILRKLDHP 204
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
NV++L + + + +L LV E++ DL + I FS IK ++ RG+ HCHR
Sbjct: 205 NVMKLEGLVTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQLFRGLEHCHR 264
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFGAKH 184
ILHRD+K +NLL+ +G LKI DFGLA ++ LTS VVT WYRAPELL GA
Sbjct: 265 RGILHRDIKGSNLLINNEGVLKIGDFGLANFYRGDGDLQLTSRVVTLWYRAPELLLGATE 324
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW-----PEVSSFS 239
Y A+D+WS G I EL P +PG+ +V+Q++ F+ G+P++ W P +SF
Sbjct: 325 YGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDYWRRATLPLATSFK 384
Query: 240 NYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+ P + L F +AL LI+ ++ + P+KR A L+S++F P P
Sbjct: 385 PSH-------PYKPVLAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFFTTEPLP 437
Query: 300 TLPQDLPK 307
P +LP+
Sbjct: 438 ANPSNLPR 445
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 191 bits (485), Expect = 1e-48
Identities = 109/305 (35%), Positives = 172/305 (55%), Gaps = 9/305 (2%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D + K K G+GTY++VY TG+ +A+K+++ + RE+ L++L H
Sbjct: 139 DSFEKLDKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREINILRKLDHP 198
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
NV++L + + + +L+LV E++ DL + + F+ IK ++ L G+ HCH
Sbjct: 199 NVMKLQCLVTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQIKCFMKQLLCGLEHCHS 258
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFGAKH 184
ILHRD+K +NLL+ DG LKI DFGLA Q+ LTS VVT WYRAPELL G+
Sbjct: 259 RGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPLTSRVVTLWYRAPELLLGSTE 318
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y A+D+WSVG I AEL + P +PG+ +V+Q++ F+ G+P++ W + + + +
Sbjct: 319 YGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEEFW----NTTKFPQA 374
Query: 245 QIYPP--PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
Y P P + L F + ++L+L+ ++ + P+KR A L S++F P P
Sbjct: 375 TSYKPQHPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEFFTTEPLPCHI 434
Query: 303 QDLPK 307
LPK
Sbjct: 435 SSLPK 439
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 191 bits (485), Expect = 1e-48
Identities = 121/321 (37%), Positives = 178/321 (54%), Gaps = 39/321 (12%)
Query: 15 KAGEGTYAVVYLGTKKST--GRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIEL 72
K G GTY VY K T G+ A+K+I + GL MSA RE+ L+ELKH NVI L
Sbjct: 103 KVGRGTYGHVYKAKWKETSDGKEYALKQIDGT----GLSMSACREIALLRELKHQNVITL 158
Query: 73 VDVFMANDNLN--LVLEFLPADLEIIIK--------DTSIMFSPADIKSWILMTLRGVHH 122
+ VF+++++ L++++ DL IIK ++ +KS + L G+H+
Sbjct: 159 IRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHY 218
Query: 123 CHRNFILHRDLKPNNLLLAPDG----QLKIADFGLARLMASPQEILTSN---VVTRWYRA 175
H N++LHRDLKP N+L+ DG ++KIAD G ARL +P + L VVT WYRA
Sbjct: 219 LHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRA 278
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIP-YLPGKDDV--------DQINVTFRALGT 226
PELL GA+HYT A+DIW++G IFAEL+ P + ++D+ DQ++ F +G
Sbjct: 279 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGF 338
Query: 227 PTDADWPEVSSFSNYN------KIQIYPPPS-REELRRRFIAATENALELISGMMIMNPK 279
P D DW ++ ++ K Y S + + R I A L+ +++M+P
Sbjct: 339 PQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPN 398
Query: 280 KRWDAVKCLQSQYFQELPEPT 300
KR + + +Q QYFQE P+PT
Sbjct: 399 KRITSEQAMQDQYFQEEPQPT 419
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 190 bits (483), Expect = 2e-48
Identities = 104/307 (33%), Positives = 169/307 (54%), Gaps = 13/307 (4%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
V Y K K G+GT+ V+ + TG+ +A+K++ K+G ++ALRE+K LQ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 67 VNVIELVDVFMAN--------DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLR 118
NV+ L+++ ++ LV +F DL ++ + + F+ ++IK + M L
Sbjct: 76 ENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLN 135
Query: 119 GVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMA----SPQEILTSNVVTRWYR 174
G+++ HRN ILHRD+K N+L+ DG LK+ADFGLAR + S T+ VVT WYR
Sbjct: 136 GLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYR 195
Query: 175 APELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE 234
PELL G + Y +D+W G I AE+ R P + G + Q+ + + G+ T WP
Sbjct: 196 PPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPN 255
Query: 235 VSSFSNYNKIQIYPPPSRE-ELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
V ++ Y K+++ R+ + R + AL+LI +++++P +R D+ L +F
Sbjct: 256 VDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFF 315
Query: 294 QELPEPT 300
P P+
Sbjct: 316 WSDPMPS 322
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 190 bits (482), Expect = 3e-48
Identities = 110/288 (38%), Positives = 168/288 (58%), Gaps = 9/288 (3%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
YT ++ G+GTY V +G +G +A+K +K +F + LREVK L++L H NV
Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKR-KFYSWDECMNLREVKSLKKLNHANV 62
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
I+L +V ND+L + E++ +L ++KD + +F + I++ + L+G+ H++
Sbjct: 63 IKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFF 122
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRD+KP NLL +KIADFGLAR + S Q T V TRWYRAPE+L + Y+S +
Sbjct: 123 HRDMKPENLLCMGPELVKIADFGLARELRS-QPPYTDYVSTRWYRAPEVLLRSSVYSSPI 181
Query: 190 DIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE---VSSFSNYNKIQI 246
D+W+VG I AEL + P PG +VD+I + LGTP +DWPE ++S N+ Q
Sbjct: 182 DVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQC 241
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
P L+ A+ A++L++ M+ +PKKR A + L+ YFQ
Sbjct: 242 VP----INLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 189 bits (481), Expect = 3e-48
Identities = 120/318 (37%), Positives = 182/318 (56%), Gaps = 25/318 (7%)
Query: 7 VDDYTKEKKAGEGTYAVVYLG-TKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+ Y K GEGTY +V+L TK R IA+K+ K S+ DG+ +A+RE+ L+E+
Sbjct: 22 LQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREIS 81
Query: 66 HVNVIELVDVFM--ANDNLNLVLEFLPADLEIIIKD----TSIMFSPADIKSWILMTLRG 119
H NV++LV+V + A+ +L L ++ DL II+ + +KS + L G
Sbjct: 82 HENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLNG 141
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD----GQLKIADFGLARLMASPQEILTSN--VVTRWY 173
+++ H N+I+HRDLKP+N+L+ D G +KIADFGLAR+ +P + L+ N VVT WY
Sbjct: 142 LNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTIWY 201
Query: 174 RAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKD--------DVDQINVTFRALG 225
RAPELL G+KHYTSAVD+W+VG IFAEL+ P G + +DQ++ F+ LG
Sbjct: 202 RAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILG 261
Query: 226 TPTDADWPEVSSFSNY-NKIQIYPPPSREELRRRFIAATEN---ALELISGMMIMNPKKR 281
PT WP + + ++ N +Q + + + A +L+S M+ +P KR
Sbjct: 262 HPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLEYDPLKR 321
Query: 282 WDAVKCLQSQYFQELPEP 299
A + L+ +YF+ P P
Sbjct: 322 ITASQALEHEYFRMDPLP 339
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 189 bits (479), Expect = 6e-48
Identities = 107/305 (35%), Positives = 174/305 (56%), Gaps = 8/305 (2%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D + K +K G+GTY+ V+ + TGR +A+K+++ F+ RE+ L++L H
Sbjct: 129 DAFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPESVRFMAREILILRKLNHP 188
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
N+I+L + + + +++LV E++ DL ++ I F+ IK ++ L G+ HCH
Sbjct: 189 NIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQIKCYMKQLLSGLDHCHA 248
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLM--ASPQEILTSNVVTRWYRAPELLFGAK 183
++HRD+K +NLL+ +G LK+ADFGLA + ++ LTS VVT WYR PELL GA
Sbjct: 249 RGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTSRVVTLWYRPPELLLGAT 308
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW--PEVSSFSNY 241
Y ++VD+WSVG +FAEL++ P L G+ +V+Q++ F+ G+P + W ++ +
Sbjct: 309 EYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPEDYWKKSKLPHAMLF 368
Query: 242 NKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTL 301
Q Y RE L+ + ++ + + LI ++ + P KR A L SQYF P
Sbjct: 369 KPQQHYDGCLRETLKLKGLSDAD--INLIETLLSIQPHKRGTASTALVSQYFTSKPFACD 426
Query: 302 PQDLP 306
P LP
Sbjct: 427 PSSLP 431
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 188 bits (478), Expect = 7e-48
Identities = 110/305 (36%), Positives = 166/305 (54%), Gaps = 9/305 (2%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D + K K G+GTY+ VY + +A+K+++ + RE++ L+ L H
Sbjct: 132 DSFEKLDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMAREIQILRRLDHP 191
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
N+I+L + + + +L LV E++ DL + +I FS + +K ++ L G+ HCH
Sbjct: 192 NIIKLEGLVTSRMSCSLYLVFEYMEHDLAGLASHPAIKFSESQVKCYLQQLLHGLDHCHS 251
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQ-EILTSNVVTRWYRAPELLFGAKH 184
+LHRD+K +NLL+ G LKIADFGLA Q + LTS VVT WYR PELL GA
Sbjct: 252 RGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQTQPLTSRVVTLWYRPPELLLGATR 311
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y +AVD+WS G I AEL P +PG+ +V+Q++ F+ G+PT+ W + S
Sbjct: 312 YGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDYWVK----SRLPHA 367
Query: 245 QIYPP--PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
I+ P P + + F + AL L+ ++ +NP R A L+S++F P P P
Sbjct: 368 TIFKPTQPYKRLVGETFKEFPQPALALLETLLSVNPDDRGTATAALKSEFFSTRPLPCDP 427
Query: 303 QDLPK 307
LPK
Sbjct: 428 SSLPK 432
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 188 bits (477), Expect = 1e-47
Identities = 100/292 (34%), Positives = 160/292 (54%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K K GEG+Y VV+ + TG+ +A+K+ S+ + ALRE++ L++LKH
Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N++ L++VF L+LV E+ + + +KS TL+ V+ CH++
Sbjct: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+HRD+KP N+L+ +K+ DFG ARL+ P + T V TRWYR+PELL G Y
Sbjct: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
VD+W++G +FAEL+ +P PGK DVDQ+ + + LG S+ ++ ++I
Sbjct: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE 298
P E L +F + AL L+ G + M+P +R + L YF+ + E
Sbjct: 242 PDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFENIRE 293
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 187 bits (476), Expect = 1e-47
Identities = 110/288 (38%), Positives = 166/288 (57%), Gaps = 9/288 (3%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
YT ++ G+GTY V LG +G IA+K++K +F + LREVK L++L H NV
Sbjct: 4 YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKR-KFYSWEECMNLREVKSLKKLNHANV 62
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
++L +V ND+L + E++ +L +IK+ + +F + I++ + L+G+ H++
Sbjct: 63 VKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFF 122
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRDLKP NLL +KIADFGLAR + S + T V TRWYRAPE+L + +Y+S +
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRS-KPPYTDYVSTRWYRAPEVLLRSTNYSSPI 181
Query: 190 DIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE---VSSFSNYNKIQI 246
D+W+VG I AE+ P PG ++D I + LGTP DWPE +SS N+ Q
Sbjct: 182 DVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQC 241
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
P L+ A+ A++L+ M+ +PKKR A + L+ YFQ
Sbjct: 242 VP----NNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 187 bits (474), Expect = 2e-47
Identities = 110/303 (36%), Positives = 170/303 (55%), Gaps = 12/303 (3%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K+ G+GT+ V L K TG +A+K +K +F + +LREVK L++L H N+
Sbjct: 45 YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMK-KKFYSWEEAMSLREVKSLKKLNHPNI 103
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
I+L +V ND L V EF+ +L ++KD F + I++ I L+G+ H+N
Sbjct: 104 IKLREVIRENDILYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMHKNGFF 163
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRD+KP N++ +KIADFGLAR + S + T V TRWYRAPE+L + Y S +
Sbjct: 164 HRDMKPENIMCNGTELVKIADFGLAREIRS-KPPYTDYVSTRWYRAPEILLRSTSYNSPI 222
Query: 190 DIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE---VSSFSNYNKIQI 246
D+W++G I AEL + P PG ++DQ+ LGTP +WPE ++S N+ Q+
Sbjct: 223 DMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQV 282
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ---ELPEPTLPQ 303
P + + ++ ++L+ MM+ NP+KR +A + L+ +YFQ +L P + Q
Sbjct: 283 VATPMEQVVN----TISKEGMKLMMDMMLWNPEKRPNANQSLRYKYFQVAEKLGAPVVSQ 338
Query: 304 DLP 306
P
Sbjct: 339 PAP 341
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 187 bits (474), Expect = 2e-47
Identities = 108/287 (37%), Positives = 157/287 (54%), Gaps = 3/287 (1%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + G+GTY V LG +K TG +A+K +K + M+ LREVK L++L H N+
Sbjct: 4 YITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMN-LREVKSLKKLSHPNI 62
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
++L +V ND L V E++ +L +IKD ++KS + L G+ HR+
Sbjct: 63 VKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFF 122
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRDLKP NLL + +KIADFGLAR + S + T V TRWYRAPE+L + +Y S +
Sbjct: 123 HRDLKPENLLCSGPDLIKIADFGLAREIRS-RPPFTDYVSTRWYRAPEVLLHSTNYGSTI 181
Query: 190 DIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPP 249
D+W++G I AEL P PG +VDQ+ LGTP DWP+ ++ + YP
Sbjct: 182 DLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFR-YPD 240
Query: 250 PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+ L ++N L+L+ M+ +P KR A + L+ YF L
Sbjct: 241 CIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYFHAL 287
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 186 bits (471), Expect = 5e-47
Identities = 104/305 (34%), Positives = 168/305 (54%), Gaps = 9/305 (2%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D + K K G+GTY+ VY TG+ +A+K+++ + RE+ L+ L H
Sbjct: 116 DTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHP 175
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
NV++L + + + +L LV +++ DL + + FS +++K + + G+ HCH
Sbjct: 176 NVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMRQLISGLEHCHS 235
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLM-ASPQEILTSNVVTRWYRAPELLFGAKH 184
+LHRD+K +NLL+ G LKIADFGLA + + + +TS VVT WYRAPELL GA
Sbjct: 236 RGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPELLLGATD 295
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y +D+WS G I AEL+ P +PG+ +V+Q++ ++ G+P++ W + +
Sbjct: 296 YGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKK----GKFTHG 351
Query: 245 QIYPP--PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
IY P P + +R F ++L LI ++ + P+ R A L+S++F P P
Sbjct: 352 AIYKPREPYKRSIRETFKDFPPSSLPLIDALLSIEPEDRQTASAALKSEFFTSEPYACEP 411
Query: 303 QDLPK 307
DLPK
Sbjct: 412 ADLPK 416
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 185 bits (469), Expect = 8e-47
Identities = 99/299 (33%), Positives = 166/299 (55%), Gaps = 20/299 (6%)
Query: 14 KKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELV 73
++ GEGTY VV+ A+K I+T + ++G+ + LRE+ +++L+H N++ L
Sbjct: 49 RRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLF 108
Query: 74 DV----------------FMANDNLNLVLEFLPADLEIIIK---DTSIMFSPADIKSWIL 114
D+ F +N L +V EF+ DL+ +++ T+ + P +KS++
Sbjct: 109 DIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSFMW 168
Query: 115 MTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYR 174
L + +CH I+HRDLKP N+L++ G +KIADFGLAR + P T VVT WYR
Sbjct: 169 QLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFSFPSRNYTHEVVTLWYR 228
Query: 175 APELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE 234
PE+L G++ Y++++D+WS+G IF+E+ P PG+ ++ Q+ F +GTP WP
Sbjct: 229 PPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIKSWPG 288
Query: 235 VSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
V SF +Y + P + ++L T N L+++ ++ P++R A L +YF
Sbjct: 289 VDSFPHYKAVFPQWPVNLKKLEET-SCLTGNGLDVLREILRYPPERRLTAKGALSHRYF 346
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 184 bits (468), Expect = 1e-46
Identities = 103/319 (32%), Positives = 167/319 (52%), Gaps = 18/319 (5%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQE 63
K+ + YT + GEGTY VY TG +A+K ++ K+G ++A+RE+K L++
Sbjct: 305 KTNLTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQ 364
Query: 64 LKHVNVIELVDVFM----------ANDNLNLVLEFLPADLEIIIKDTSIM-FSPADIKSW 112
L H N++ L+D+ + N LV E++ DL +++ ++ F+ I S
Sbjct: 365 LHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSL 424
Query: 113 ILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRW 172
L G+ + H LHRD+K +N+L+ G+LKIAD GLARL + T+ V+T W
Sbjct: 425 FKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLW 484
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YR PELL G + Y A+D+WS G + EL R P G ++ Q+ + + G+P +W
Sbjct: 485 YRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNW 544
Query: 233 PEVSSFSNYNKIQI---YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQ 289
PE++ +N ++ Y REE A++L+ M+ +NP+KR A + L
Sbjct: 545 PELTELVGWNTFRMKRTYQRRIREEFEH---IMPREAVDLLDKMLTLNPEKRISAKEALN 601
Query: 290 SQYFQELPEPTL-PQDLPK 307
+ + L T+ P LP+
Sbjct: 602 HPWIRSLEHTTVQPLKLPQ 620
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 184 bits (468), Expect = 1e-46
Identities = 111/308 (36%), Positives = 163/308 (52%), Gaps = 15/308 (4%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
+ + K K G+GTY+ VY TG+ +A+K+++ RE+ L++L H
Sbjct: 154 ESFEKLDKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMAREINILRKLDHP 213
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
NV++L + + + +L LV E++ DL + + F+ + IK ++ L G+ HCH
Sbjct: 214 NVMKLECLVTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQIKCYMKQLLSGLEHCHS 273
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFGAKH 184
ILHRD+K NLL+ DG LKI DFGLA + Q+ LTS VVT WYRAPELL GA
Sbjct: 274 RGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQDQPLTSRVVTLWYRAPELLLGATE 333
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW-----PEVSSFS 239
Y +D+WSVG I EL L P +PG+ +V+Q++ F+ G+P+D W P +SF
Sbjct: 334 YGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSDDYWQKTKLPLATSFK 393
Query: 240 NYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
P + L F +AL L+ ++ + P KR A L S++F P P
Sbjct: 394 PQQ-------PYKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTLSSKFFTMEPLP 446
Query: 300 TLPQDLPK 307
LPK
Sbjct: 447 CNVSSLPK 454
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 184 bits (466), Expect = 2e-46
Identities = 109/288 (37%), Positives = 164/288 (56%), Gaps = 9/288 (3%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
YT ++ G+GTY V LG +G IA+K++K +F + REVK L++L H NV
Sbjct: 4 YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKR-KFYSWEECMNQREVKSLKKLNHANV 62
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
++L +V ND+L + E++ +L +IK+ + +F + I++ + L+G+ H+
Sbjct: 63 VKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKLGFF 122
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAV 189
HRDLKP NLL +KIADFGLAR + S + T V TRWYRAPE+L + +Y+S +
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRS-KPPYTDYVSTRWYRAPEVLLRSTNYSSPI 181
Query: 190 DIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE---VSSFSNYNKIQI 246
D+W+VG I AE+ P PG ++D I + LGTP DWPE +SS N+ Q
Sbjct: 182 DVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQC 241
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
P L+ A+ A++L+ M+ +PKKR A + L+ YFQ
Sbjct: 242 VP----NNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 183 bits (465), Expect = 2e-46
Identities = 104/303 (34%), Positives = 165/303 (54%), Gaps = 9/303 (2%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K +K G+GTY+ VY +G+ +A+K+++ + RE+ L+ L H NV
Sbjct: 114 YEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLNHPNV 173
Query: 70 IELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNF 127
I+L + + + +L LV E++ DL + + F +K ++ L G+ HCH
Sbjct: 174 IKLQGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEHCHSRG 233
Query: 128 ILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQ-EILTSNVVTRWYRAPELLFGAKHYT 186
+LHRD+K +NLL+ DG LKIADFGLA Q + +TS VVT WYR PELL GA Y
Sbjct: 234 VLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSRVVTLWYRPPELLLGATSYG 293
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ VD+WS G I AEL+ P +PG+ +V+Q++ F+ G+P+D+ W + +
Sbjct: 294 TGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKKY----RLPNATL 349
Query: 247 YPP--PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQD 304
+ P P + + F T +++ L+ ++ ++P R + L S++F P P P
Sbjct: 350 FKPQHPYKRCVAEAFNGFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTEPLPCDPSS 409
Query: 305 LPK 307
LPK
Sbjct: 410 LPK 412
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 183 bits (465), Expect = 2e-46
Identities = 108/304 (35%), Positives = 167/304 (54%), Gaps = 13/304 (4%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
S ++ + K +K GEGTY VY +K+TG +A+K+ + + ++G+ + LRE+ L+ L
Sbjct: 11 SAMEAFEKLEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREISILRML 70
Query: 65 -KHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKD---TSIMFSPADIKSWILM 115
+ +++ L+DV + L LV E++ DL+ I+ +K +
Sbjct: 71 ARDPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQ 130
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLLAPDGQ-LKIADFGLARLMASPQEILTSNVVTRWYR 174
+G+ CH + +LHRDLKP+NLL+ LKIAD GLAR P + T ++T WYR
Sbjct: 131 LCKGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTLPMKKYTHEILTLWYR 190
Query: 175 APELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE 234
APE+L GA HY++ VD+WSVG IFAEL+ + G ++ Q+ FR LGTP + WP
Sbjct: 191 APEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVWPG 250
Query: 235 VSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
VS ++++ YP L E L+L+S M+ P KR A K ++ YF
Sbjct: 251 VSKLKDWHE---YPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYFD 307
Query: 295 ELPE 298
+LP+
Sbjct: 308 DLPD 311
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 183 bits (464), Expect = 3e-46
Identities = 113/316 (35%), Positives = 165/316 (51%), Gaps = 35/316 (11%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFL-------Q 62
+ K +K G+GTY+ VY + + +A+K ++ D+S L VKF+ +
Sbjct: 137 FEKLEKIGQGTYSSVYKARDLTNNKIVALKRVR-------FDLSDLESVKFMAREIIVMR 189
Query: 63 ELKHVNVIELVDVFMAN--DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGV 120
L H NV++L + A+ +L LV E++ DL + I FS +K ++ L G+
Sbjct: 190 RLDHPNVLKLEGLITASVSSSLYLVFEYMDHDLVGLASIPGIKFSEPQVKCYMQQLLSGL 249
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI--LTSNVVTRWYRAPEL 178
HHCH +LHRD+K +NLL+ +G LKIADFGLA PQ LTS VVT WYR PEL
Sbjct: 250 HHCHSRGVLHRDIKGSNLLIDSNGVLKIADFGLATFF-DPQNCVPLTSRVVTLWYRPPEL 308
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSF 238
L GA HY VD+WS G I EL P L GK +V+Q++ F+ G+PT+ W
Sbjct: 309 LLGACHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPTEDYW------ 362
Query: 239 SNYNKIQIYPP-------PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
K+++ P P + F N L L+ ++ ++P +R A + L+S+
Sbjct: 363 ---RKLKLPPSAAFRPALPYGRRVAEMFKDLPTNVLSLLEALLSIDPDRRGSAARALESE 419
Query: 292 YFQELPEPTLPQDLPK 307
YF+ P P LPK
Sbjct: 420 YFRTEPFACDPSSLPK 435
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 183 bits (464), Expect = 3e-46
Identities = 108/297 (36%), Positives = 164/297 (54%), Gaps = 8/297 (2%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLD-MSALREVKFLQELKHVN 68
Y K G G Y VV + + +A+K+I + F++ +D + LRE+K L+ L+H N
Sbjct: 32 YVPIKPIGRGAYGVVCSSVNRESNERVAIKKIH-NVFENRIDALRTLRELKLLRHLRHEN 90
Query: 69 VIELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
V+ L DV MAN ++ LV E + DL IIK + ++ S + ++ LRG+ +
Sbjct: 91 VVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQVL-SNDHCQYFLFQLLRGLKYI 149
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H ILHRDLKP NLL+ + LKI DFGLAR + + +T VVTRWYRAPELL
Sbjct: 150 HSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQFMTEYVVTRWYRAPELLLCCD 209
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
+Y +++D+WSVG IFAEL+ R P PG + ++QI + LG+ + D + +
Sbjct: 210 NYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREEDLEFIDNPKAKRY 269
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
I+ P R + A A++L+ M++++P KR + LQ Y L +P+
Sbjct: 270 IESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEALQHPYMAPLYDPS 326
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 181 bits (460), Expect = 9e-46
Identities = 104/310 (33%), Positives = 167/310 (53%), Gaps = 6/310 (1%)
Query: 3 LKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTS-QFKDGLDMSALREVKFL 61
L D + K K G GTY+ VY TG +A+K+++ ++ L A RE+ L
Sbjct: 131 LPRKADSFEKIDKIGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMA-REILIL 189
Query: 62 QELKHVNVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRG 119
+ L H NVI+L + + + +L LV ++ DL + I F+ +K ++ L G
Sbjct: 190 RRLDHPNVIKLEGLVTSRMSSSLYLVFRYMDHDLAGLAASPEIKFTEQQVKCYMKQLLSG 249
Query: 120 VHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLM-ASPQEILTSNVVTRWYRAPEL 178
+ HCH +LHRD+K +NLL+ G L+I DFGLA AS ++ +T+ VVT WYR+PEL
Sbjct: 250 LEHCHNRGVLHRDIKGSNLLIDDGGVLRIGDFGLATFFDASKRQEMTNRVVTLWYRSPEL 309
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSF 238
L G Y+ VD+WS G I AEL+ +PG+++V+Q++ ++ G+P++ W ++
Sbjct: 310 LHGVVEYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIRLP 369
Query: 239 SNYNKIQIYP-PPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
S + P P + +R + + AL L+ ++ ++P +R A L S +F P
Sbjct: 370 STHKHAHHKPLPQYKRRIREVYKDFSPEALSLLDTLLALDPAERQTATDVLMSDFFTTEP 429
Query: 298 EPTLPQDLPK 307
P DLPK
Sbjct: 430 LACQPSDLPK 439
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 181 bits (460), Expect = 9e-46
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 13/296 (4%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDV 75
G G Y +V T T +A+K+I + F + +D LRE+K L + H NVI++ D+
Sbjct: 40 GRGAYGIVCCATNSETNEEVAIKKIANA-FDNRVDAKRTLREIKLLSHMDHDNVIKIKDI 98
Query: 76 FMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
+ ++ +V E + DL II+ T + + + ++ LRG+ + H +LH
Sbjct: 99 IELPEKERFEDVYIVYELMDTDLHQIIRSTQTL-TDDHCQYFLYQILRGLKYIHSANVLH 157
Query: 131 RDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVD 190
RDLKP+NL+L + LKI DFGLAR ++ EI+T VVTRWYRAPELL + YT A+D
Sbjct: 158 RDLKPSNLVLNTNCDLKICDFGLART-SNETEIMTEYVVTRWYRAPELLLNSSEYTGAID 216
Query: 191 IWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPP 250
IWSVG IF E++ R PGKD V Q+ + LG+P D+D + S + ++ P
Sbjct: 217 IWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSDLDFLRSDNARKYVKQLPHV 276
Query: 251 SREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL----PEPTLP 302
++ R +F + AL+L M++ +P KR + L+ Y L EPT P
Sbjct: 277 QKQSFREKFPNISPMALDLAEKMLVFDPSKRITVDEALKQPYLASLHEINEEPTCP 332
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 181 bits (459), Expect = 1e-45
Identities = 104/305 (34%), Positives = 161/305 (52%), Gaps = 9/305 (2%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D + K +K G+GTY+ VY T + +A+K+++ + RE+ L+ L H
Sbjct: 161 DSFEKLEKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMAREIIILRRLDHP 220
Query: 68 NVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
NV++L + + + ++ L+ E++ DL + I FS A IK ++ L G+ HCH
Sbjct: 221 NVMKLEGLITSRVSGSMYLIFEYMEHDLAGLASTPGINFSEAQIKCYMKQLLHGLEHCHS 280
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQ-EILTSNVVTRWYRAPELLFGAKH 184
+LHRD+K +NLLL + LKI DFGLA Q + LTS VVT WYR PELL G+
Sbjct: 281 RGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQGHQKQPLTSRVVTLWYRPPELLLGSTD 340
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y VD+WS G I AEL P +PG+ +V+Q++ F+ G+P++ W S
Sbjct: 341 YGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEEYW----KISKLPHA 396
Query: 245 QIYPP--PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
I+ P P + + F + +AL L+ ++ + P R L+S++F P + P
Sbjct: 397 TIFKPQQPYKRCVAETFKSLPSSALALVEVLLAVEPDARGTTASALESEFFTTSPLASDP 456
Query: 303 QDLPK 307
LPK
Sbjct: 457 SSLPK 461
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 180 bits (457), Expect = 2e-45
Identities = 112/304 (36%), Positives = 159/304 (51%), Gaps = 28/304 (9%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK- 65
+D Y + GEG + +V+ TG IA+K++ + +DG ALRE+K LQE++
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMED 60
Query: 66 HVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
+ V++L VF L EF+ +DL +++ + A +KS++ M L+GV CH
Sbjct: 61 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
N I+HRDLKP NLL++ GQLKIADFGLAR+ SP G++ Y
Sbjct: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVF-SPD-------------------GSRLY 160
Query: 186 TSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQ 245
T V SVG I EL+ P PGK+D++Q+ R LGTP WPE++ +YNKI
Sbjct: 161 THQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKIS 220
Query: 246 I---YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
P P E L + AL+L+ ++ P +R A K L QYF P P P
Sbjct: 221 FKEQVPMPLEEVLP----DVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHP 276
Query: 303 QDLP 306
+LP
Sbjct: 277 SELP 280
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 180 bits (456), Expect = 3e-45
Identities = 105/294 (35%), Positives = 157/294 (52%), Gaps = 8/294 (2%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
+D Y K + GEG+Y VVY + TG +AVK S+ + ALRE++ L+ LKH
Sbjct: 1 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIK-DTSIMFSPADIKSWIL-MTLRGVHHCH 124
N++ L++VF L+LV EF +L ++ + + P + I TL GV +CH
Sbjct: 61 PNLVSLLEVFRRKRRLHLVFEF--CELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCH 118
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKH 184
+ LHRD+KP N+LL GQ+K+ DFG AR++ SP E T V TRWYRAPELL G
Sbjct: 119 KQGCLHRDIKPENILLTAQGQVKLCDFGFARML-SPGENYTDYVATRWYRAPELLVGDTQ 177
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
Y + VD+W++G +FAEL+ PG+ DVDQ+ + + LG + I
Sbjct: 178 YGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGI 237
Query: 245 QIYPPPSREELRRRFIAATEN---ALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+ PP+ E L + A ++ ++ + + +P KRW K + YF +
Sbjct: 238 TLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDD 291
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 179 bits (454), Expect = 5e-45
Identities = 103/302 (34%), Positives = 162/302 (53%), Gaps = 6/302 (1%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
+ K+++ G GT++ V+ +++A+K I+ RE+ L++L H NV
Sbjct: 103 FEKQEQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDHPNV 162
Query: 70 IELVDVFMANDN---LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
I+L + + + + L L+ E++ DL + + FS +K ++ LRG+ HCH N
Sbjct: 163 IKLEGLMLVDHDSSTLYLIFEYMEHDLLGLSSLLGVHFSEPQVKCYMRQLLRGLDHCHTN 222
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFGAKHY 185
+LHRD+K +NLL+ DG LKIADFGLA + LT++V T WYR PELL GA HY
Sbjct: 223 HVLHRDMKSSNLLINGDGVLKIADFGLATFFDPHNSVPLTTHVATLWYRPPELLLGASHY 282
Query: 186 TSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQ 245
VD+WS G + EL P LPGK++ DQ++ F+ G+P+D W ++ +
Sbjct: 283 GIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSDDYWTKLKLQLSTPLRP 342
Query: 246 IYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQDL 305
IYP S + F + + L+ ++ ++P R A L+S+YF+ P P L
Sbjct: 343 IYPYGS--HIAETFKQFPASVISLLETLLSIDPDFRGTAASALKSKYFKTEPLACDPSCL 400
Query: 306 PK 307
PK
Sbjct: 401 PK 402
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 179 bits (454), Expect = 5e-45
Identities = 109/301 (36%), Positives = 164/301 (54%), Gaps = 22/301 (7%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDV 75
G+G Y +V T S+A+K+I + F + +D LRE+K L+ + H N++ + D+
Sbjct: 70 GKGAYGIVCSAMNSETNESVAIKKIANA-FDNKIDAKRTLREIKLLRHMDHENIVAIRDI 128
Query: 76 FM-----ANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
A +++ + E + DL II+ + S + ++ LRG+ + H +LH
Sbjct: 129 IPPPLRNAFNDVYIAYELMDTDLHQIIRSNQAL-SEEHCQYFLYQILRGLKYIHSANVLH 187
Query: 131 RDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVD 190
RDLKP+NLLL + LKI DFGLAR+ S + +T VVTRWYRAPELL + YT+A+D
Sbjct: 188 RDLKPSNLLLNANCDLKICDFGLARV-TSESDFMTEYVVTRWYRAPELLLNSSDYTAAID 246
Query: 191 IWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK---IQIY 247
+WSVG IF ELM R P PG+D V Q+ + +GTP++ E F N N I+
Sbjct: 247 VWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSE----EELEFLNENAKRYIRQL 302
Query: 248 PPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL------PEPTL 301
PP R+ + +F A++LI M+ +P++R + L Y L PE T+
Sbjct: 303 PPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHPYLNSLHDISDEPECTI 362
Query: 302 P 302
P
Sbjct: 363 P 363
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 178 bits (451), Expect = 1e-44
Identities = 119/333 (35%), Positives = 176/333 (52%), Gaps = 44/333 (13%)
Query: 15 KAGEGTYAVVYLGTKKS--TGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIEL 72
K G GTY VY +K + A+K+I+ + G+ MSA RE+ L+ELKH NVI L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGT----GISMSACREIALLRELKHPNVIAL 81
Query: 73 VDVFMANDNLN--LVLEFLPADLEIIIK--------DTSIMFSPADIKSWILMTLRGVHH 122
VF+++ + L+ ++ DL IIK + + +KS + L G+H+
Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 123 CHRNFILHRDLKPNNLLLAPDG----QLKIADFGLARLMASPQEILTSN---VVTRWYRA 175
H N++LHRDLKP N+L+ +G ++KIAD G ARL SP + L VVT WYRA
Sbjct: 142 LHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRA 201
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIP-YLPGKDDV--------DQINVTFRALGT 226
PELL GA+HYT A+DIW++G IFAEL+ P + ++D+ DQ++ F +G
Sbjct: 202 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGF 261
Query: 227 PTDADWPEVSSFSNYNKIQ------IYPPPSR-EELRRRFIAATENALELISGMMIMNPK 279
P D DW ++ Y +Q Y S + + + + L+ ++ M+P
Sbjct: 262 PADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPT 321
Query: 280 KRWDAVKCLQSQYFQELPEPT-----LPQDLPK 307
KR + + LQ YFQE P PT LP +P+
Sbjct: 322 KRITSEQALQDPYFQEDPLPTLDICRLPDSIPQ 354
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 177 bits (449), Expect = 2e-44
Identities = 98/294 (33%), Positives = 160/294 (54%), Gaps = 10/294 (3%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K K GEGTYA V+ G T + +A+KEI+ Q ++G +A+REV L+ L+H
Sbjct: 358 LETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQ-EEGAPCTAIREVSLLRNLRH 416
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
NV+ L D+ + L LV E++ DL+ + + +I+ ++ LRG+ +CH+
Sbjct: 417 ANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQR 476
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+LHRDLKP NLL+ G+LK+ADFGLAR + P + ++ VVT WYR P++L G+ Y+
Sbjct: 477 RVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYS 536
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ +D+W VG I E++ PG +Q+ + FR LG+P P + K
Sbjct: 537 THIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTIC-----EKPTF 591
Query: 247 YPPPSR----EELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
YP +R + L R+ + EL+ + K R A + ++ + + +
Sbjct: 592 YPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFLRTI 645
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 177 bits (449), Expect = 2e-44
Identities = 98/294 (33%), Positives = 160/294 (54%), Gaps = 10/294 (3%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K K GEGTYA V+ G T + +A+KEI+ Q ++G +A+REV L+ L+H
Sbjct: 235 LETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQ-EEGAPCTAIREVSLLRNLRH 293
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
NV+ L D+ + L LV E++ DL+ + + +I+ ++ LRG+ +CH+
Sbjct: 294 ANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQR 353
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+LHRDLKP NLL+ G+LK+ADFGLAR + P + ++ VVT WYR P++L G+ Y+
Sbjct: 354 RVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYS 413
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ +D+W VG I E++ PG +Q+ + FR LG+P P + K
Sbjct: 414 THIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTIC-----EKPTF 468
Query: 247 YPPPSR----EELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
YP +R + L R+ + EL+ + K R A + ++ + + +
Sbjct: 469 YPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFLRTI 522
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 177 bits (449), Expect = 2e-44
Identities = 109/306 (35%), Positives = 168/306 (54%), Gaps = 15/306 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSAL----REVKFLQELK 65
+ K +K G+GTY+ VY + +A+K+++ D DM ++ RE+ ++ L
Sbjct: 213 FEKLEKIGQGTYSSVYRARDLLHNKIVALKKVRF----DLNDMESVKFMAREIIVMRRLD 268
Query: 66 HVNVIELVDVFMA--NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H NV++L + A + +L LV E++ DL + + F+ +K ++ L G+ HC
Sbjct: 269 HPNVLKLEGLITAPVSSSLYLVFEYMDHDLLGLSSLPGVKFTEPQVKCYMRQLLSGLEHC 328
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFGA 182
H +LHRD+K +NLL+ G LKIADFGLA + + LTS+VVT WYR PELL GA
Sbjct: 329 HSRGVLHRDIKGSNLLIDSKGVLKIADFGLATFFDPAKSVSLTSHVVTLWYRPPELLLGA 388
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
HY VD+WS G I EL P LPGK +V+Q++ F+ G+PT+ W + S+
Sbjct: 389 SHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPTENYWRKQKLPSSAG 448
Query: 243 -KIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTL 301
K I P R ++ F + L L+ ++ ++P R A + L+S+YF+ P
Sbjct: 449 FKTAI---PYRRKVSEMFKDFPASVLSLLETLLSIDPDHRSSADRALESEYFKTKPFACD 505
Query: 302 PQDLPK 307
P +LPK
Sbjct: 506 PSNLPK 511
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 177 bits (448), Expect = 2e-44
Identities = 104/314 (33%), Positives = 163/314 (51%), Gaps = 19/314 (6%)
Query: 10 YTKEKKAGEGTYAVVYLGT-KKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVN 68
Y K K G+GT+ V+ KK + +A+K++ K+G ++ALRE++ LQ LKH N
Sbjct: 50 YEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHEN 109
Query: 69 VIELVDVFMAN--------DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGV 120
V+ L+++ LV +F DL ++ + ++ FS +IK + L G+
Sbjct: 110 VVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGL 169
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI----LTSNVVTRWYRAP 176
++ H N ILHRD+K N+L+ G LK+ADFGLAR + P+ T+ VVT WYR P
Sbjct: 170 YYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPP 229
Query: 177 ELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS 236
ELL G ++Y VD+W G I AE+ R P + G + Q+ + G+ T WP V
Sbjct: 230 ELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVE 289
Query: 237 SFSNYNKIQIYPPPSREELRRRF--IAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
Y I++ P + ++ R + +L+ ++ ++PKKR DA L +F
Sbjct: 290 ELELYKSIEL-PKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFW 348
Query: 295 ELPEPTLPQDLPKL 308
P +P DL K+
Sbjct: 349 TDP---MPSDLSKM 359
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 176 bits (447), Expect = 3e-44
Identities = 110/334 (32%), Positives = 168/334 (49%), Gaps = 39/334 (11%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFK-DGLDMSALREVKFLQELKHVN 68
+ K+ G GTY +VY K KE + G MSA RE+ +EL+H N
Sbjct: 26 FENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMIEGQGFSMSACREIALFRELRHPN 85
Query: 69 VIELVDVFMANDN-LNLVLEFLPADLEIIIKD--------TSIMFSPADIKSWILMTLRG 119
+I L VF+ N+ + L+L++ DL +IK IM +K+ + L G
Sbjct: 86 LICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMVKNILFQILSG 145
Query: 120 VHHCHRNFILHRDLKPNNLLLAPDG------QLKIADFGLARLMASPQEILTSN---VVT 170
+H+ H N++LHRDLKP N+LL DG ++KIAD G +R+ A+P + + VVT
Sbjct: 146 MHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVT 205
Query: 171 RWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDD---------VDQINVTF 221
WYRAPELL GAKHYT A+D+W++G IFAEL+ P K++ DQ+ F
Sbjct: 206 FWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIF 265
Query: 222 RALGTPTDADWPEVSSFSNYNK-----------IQIYPPPSREELRRRFIAATENALELI 270
LG P+DADWP++ ++ + IQ +P + I + + L+
Sbjct: 266 HLLGYPSDADWPDMKKMPDHQRLLSDARNEGTPIQTFPNSLHRYFDKWKINSQSSPYRLL 325
Query: 271 SGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQD 304
++ ++P KR + + YF+++ P D
Sbjct: 326 VKLLTVDPTKRVSCEEAMNDIYFRKMERPPRETD 359
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 174 bits (441), Expect = 1e-43
Identities = 107/289 (37%), Positives = 155/289 (53%), Gaps = 9/289 (3%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDV 75
G G Y +V T +A+K+I + F + +D LRE+K L+ L H N+I + DV
Sbjct: 45 GRGAYGIVCSVLDTETNELVAMKKIANA-FDNHMDAKRTLREIKLLRHLDHENIIAIRDV 103
Query: 76 FMAN-----DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
++ + E + DL II+ + S + ++ LRG+ + H I+H
Sbjct: 104 VPPPLRRQFSDVYISTELMDTDLHQIIRSNQSL-SEEHCQYFLYQLLRGLKYIHSANIIH 162
Query: 131 RDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVD 190
RDLKP+NLLL + LKI DFGLAR S + +T VVTRWYRAPELL + YT+A+D
Sbjct: 163 RDLKPSNLLLNANCDLKICDFGLAR-PTSENDFMTEYVVTRWYRAPELLLNSSDYTAAID 221
Query: 191 IWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPP 250
+WSVG IF ELM R P PGKD V Q+ + LGTPT++D + I+ P
Sbjct: 222 VWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDLGFTHNEDAKRYIRQLPNF 281
Query: 251 SREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
R+ L + F A++L+ M+ +P +R + L QY +L +P
Sbjct: 282 PRQPLAKLFSHVNPMAIDLVDRMLTFDPNRRITVEQALNHQYLAKLHDP 330
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 174 bits (440), Expect = 2e-43
Identities = 96/290 (33%), Positives = 162/290 (55%), Gaps = 15/290 (5%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
+ K +K G+GTY+ V+ + TG+ +A+K++K + RE+ L++L H N+
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVETGKMVALKKVKFDNLQPESIRFMAREILILRKLNHPNI 164
Query: 70 IELVDVFM--ANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNF 127
++L + A+ ++ LV E++ DL + + I F+ IK ++ L G+ HCH
Sbjct: 165 MKLEGIVTSRASSSIYLVFEYMEHDLAGLSSNPDIRFTEPQIKCYMKQLLWGLEHCHMRG 224
Query: 128 ILHRDLKPNNLLLAPDGQLKIADFGLARLMA-SPQEILTSNVVTRWYRAPELLFGAKHYT 186
++HRD+K +N+L+ G LK+ DFGLA ++ S + LTS VVT WYRAPELL G+ Y
Sbjct: 225 VIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSRVVTLWYRAPELLMGSTSYG 284
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW-----PEVSSFSNY 241
+VD+WSVG +FAE+++ P L G+ +++Q++ ++ G+P D+ W P +SF
Sbjct: 285 VSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSPQDSFWKRTKLPHATSFKPQ 344
Query: 242 NKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
+ + LR R + + L+ ++ M P KR A L S+
Sbjct: 345 HTYE-------ATLRERCKDLSATGVYLLETLLSMEPDKRGTASSALNSE 387
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 173 bits (439), Expect = 2e-43
Identities = 106/296 (35%), Positives = 159/296 (52%), Gaps = 8/296 (2%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLD-MSALREVKFLQELKHVN 68
Y K G G Y VV T +A+K+I + +++ +D + LRE+K L+ L+H N
Sbjct: 32 YMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIH-NVYENRIDALRTLRELKLLRHLRHEN 90
Query: 69 VIELVDVFMANDNLN-----LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
VI L DV M ++ LV E + DL IIK + ++ S + ++ LRG+ +
Sbjct: 91 VIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQVL-SNDHCQYFLFQLLRGLKYI 149
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H ILHRDLKP NLL+ + LKI DFGLAR + + +T VVTRWYRAPELL
Sbjct: 150 HSANILHRDLKPGNLLVNANCDLKICDFGLARASNTKGQFMTEYVVTRWYRAPELLLCCD 209
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
+Y +++D+WSVG IFAEL+ R P G + ++Q+ + LG+ + D + +
Sbjct: 210 NYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQREEDLEFIDNPKAKRY 269
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
I+ P L R + A A++L+ M++ +P KR + LQ Y L +P
Sbjct: 270 IRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKRISVSEALQHPYMAPLYDP 325
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 172 bits (437), Expect = 4e-43
Identities = 114/321 (35%), Positives = 170/321 (52%), Gaps = 39/321 (12%)
Query: 15 KAGEGTYAVVYLGTKKS--TGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIEL 72
K G GTY VY +K + A+K+I+ + G+ MSA RE+ L+ELKH NVI L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLRELKHPNVISL 81
Query: 73 VDVFM--ANDNLNLVLEFLPADLEIIIK--------DTSIMFSPADIKSWILMTLRGVHH 122
VF+ A+ + L+ ++ DL IIK + +KS + L G+H+
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 123 CHRNFILHRDLKPNNLLLAPDG----QLKIADFGLARLMASPQEILTSN---VVTRWYRA 175
H N++LHRDLKP N+L+ +G ++KIAD G ARL SP + L VVT WYRA
Sbjct: 142 LHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRA 201
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIP-YLPGKDDV--------DQINVTFRALGT 226
PELL GA+HYT A+DIW++G IFAEL+ P + ++D+ DQ++ F +G
Sbjct: 202 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGF 261
Query: 227 PTDADWPEVSSFSNYNKI------QIYPPPSR-EELRRRFIAATENALELISGMMIMNPK 279
P D DW ++ ++ + Y S + + + + A L+ ++ M+P
Sbjct: 262 PADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPI 321
Query: 280 KRWDAVKCLQSQYFQELPEPT 300
KR + + +Q YF E P PT
Sbjct: 322 KRITSEQAMQDPYFLEDPLPT 342
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 172 bits (436), Expect = 6e-43
Identities = 93/305 (30%), Positives = 162/305 (52%), Gaps = 9/305 (2%)
Query: 1 MTLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKF 60
+T + + Y + + GEGTY VY +T + +A+K+++ ++G ++++RE+K
Sbjct: 174 LTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKL 233
Query: 61 LQELKHVNVIELVDVFMANDN-LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRG 119
LQ H NV + ++ + + + ++ E+ DL ++ + + S + K L G
Sbjct: 234 LQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLG 293
Query: 120 VHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELL 179
+ + H N ILHRD+K +N+L+ G LKI DFGLAR M S + T+ V+T WYR PELL
Sbjct: 294 MEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADY-TNRVITLWYRPPELL 352
Query: 180 FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
G +Y + VD+W G + EL + G ++++QI F+ +GTPT WP +
Sbjct: 353 LGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMP 412
Query: 240 NYNKIQIYPPPSREELRR-----RFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
+ I P + + + + + + L+L ++ + KR+ A + LQS YF+
Sbjct: 413 WF--FMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFK 470
Query: 295 ELPEP 299
E P+P
Sbjct: 471 EEPKP 475
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 172 bits (436), Expect = 6e-43
Identities = 109/302 (36%), Positives = 158/302 (52%), Gaps = 15/302 (4%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K K GEG+Y VV+ K++G+ +AVK+ S+ + ALRE++ L++LKH
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR- 125
N++ L++VF ++LV E+ L + + + D S I+ LR V R
Sbjct: 61 PNLVNLIEVFRRKRKMHLVFEYCDHTL---LNELERNPNGMDSDS-IVGRLRSVADRSRL 116
Query: 126 ----NFIL-----HRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAP 176
N I+ HRD+KP N+L+ G +KI DFG A+++ P + T V TRWYRAP
Sbjct: 117 APKNNQIMILQCIHRDIKPENILITKQGIIKICDFGFAQILI-PGDAYTDYVATRWYRAP 175
Query: 177 ELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS 236
ELL G Y S+VDIW++G +FAEL+ P PGK DVDQ+ + R LG
Sbjct: 176 ELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFK 235
Query: 237 SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
S ++ I I P E L +F AL + G + MNP R + L+S YF
Sbjct: 236 SNGFFHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSF 295
Query: 297 PE 298
E
Sbjct: 296 QE 297
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 171 bits (434), Expect = 9e-43
Identities = 105/307 (34%), Positives = 172/307 (55%), Gaps = 18/307 (5%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQEL-K 65
+ + +K+ G+G Y +V+ K + ++A+K+I + F++ D REV FLQE K
Sbjct: 11 EKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDA-FRNPTDSQRTFREVMFLQEFGK 69
Query: 66 HVNVIELVDVFMANDNLNLVL--EFLPADLEIIIKDTSIMFSPADI-KSWILMTL-RGVH 121
H NVI+L ++F A+++ ++ L EF+ ADL +IK SI+ D+ K +I+ L R +
Sbjct: 70 HPNVIKLYNIFRADNDRDIYLAFEFMEADLHNVIKKGSIL---KDVHKQYIMCQLFRAIR 126
Query: 122 HCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI--------LTSNVVTRWY 173
H +LHRDLKP+N+LL D ++K+ADFGLAR ++S ++ LT V TRWY
Sbjct: 127 FLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWY 186
Query: 174 RAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWP 233
R+PE+L AK YT VD+WS+G I AE+++ PG ++QI + P+ AD
Sbjct: 187 RSPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIA 246
Query: 234 EVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
+ S + ++ P R+ L + A++++ ++I P+KR +CL Y
Sbjct: 247 SIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHPYV 306
Query: 294 QELPEPT 300
+ P+
Sbjct: 307 VQFHNPS 313
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 171 bits (434), Expect = 9e-43
Identities = 103/286 (36%), Positives = 153/286 (53%), Gaps = 9/286 (3%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDV 75
G G Y +V T TG +A+K+I + F + +D LRE+K L+ + H NVI + D+
Sbjct: 50 GRGAYGIVCAATNSETGEEVAIKKIGNA-FDNIIDAKRTLREIKLLKHMDHENVIAVKDI 108
Query: 76 FMA--NDNLN---LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
+N N +V E + DL II+ + + + ++ LRG+ + H +LH
Sbjct: 109 IKPPQRENFNDVYIVYELMDTDLHQIIRSNQPL-TDDHCRFFLYQLLRGLKYVHSANVLH 167
Query: 131 RDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVD 190
RDLKP+NLLL + LK+ DFGLAR S + +T VVTRWYRAPELL YT+A+D
Sbjct: 168 RDLKPSNLLLNANCDLKLGDFGLARTK-SETDFMTEYVVTRWYRAPELLLNCSEYTAAID 226
Query: 191 IWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPP 250
IWSVG I E M R P PGKD V Q+ + +G+P D+ + S + ++ P
Sbjct: 227 IWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQY 286
Query: 251 SREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
R+ RF + A++L+ M++ +P +R + L Y L
Sbjct: 287 PRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITVDEALCHPYLAPL 332
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 171 bits (434), Expect = 9e-43
Identities = 91/278 (32%), Positives = 153/278 (54%), Gaps = 4/278 (1%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y +K GEG + V+ + +A+K++ + ++ LRE+K LQ K +
Sbjct: 9 YKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSEYI 68
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
++++D++ L+LVLE+ P L +K S ++ + +G+ + H ++
Sbjct: 69 LDIIDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLM 128
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMASPQE--ILTSNVVTRWYRAPELLFGAKHYTS 187
HRD+KP NLL++ LKIADFGLARL E + + V TRWYRAPE+LFG++ Y +
Sbjct: 129 HRDIKPANLLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGT 188
Query: 188 AVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIY 247
VD+W+ G + AE++ +P G D++Q+ + R LG+P WPE++S +Y+KI+ +
Sbjct: 189 GVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLPDYSKIR-F 247
Query: 248 PPPSREELRRRFIAATENA-LELISGMMIMNPKKRWDA 284
P F + T + L+S +++ NPK R A
Sbjct: 248 PNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKNRLKA 285
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 170 bits (431), Expect = 2e-42
Identities = 103/296 (34%), Positives = 159/296 (52%), Gaps = 8/296 (2%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLD-MSALREVKFLQELKHVN 68
Y K G G Y VV + T +A+K+I + F++ +D + LRE+K L+ ++H N
Sbjct: 32 YVPIKPIGRGAYGVVCSSINRETNERVAIKKIH-NVFENRVDALRTLRELKLLRHVRHEN 90
Query: 69 VIELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
VI L DV + + ++ LV E + DL IIK + + S K ++ LRG+ +
Sbjct: 91 VIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSSQSL-SDDHCKYFLFQLLRGLKYL 149
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H ILHRDLKP NLL+ + LKI DFGLAR ++ +T VVTRWYRAPELL
Sbjct: 150 HSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGNEQFMTEYVVTRWYRAPELLLCCD 209
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
+Y +++D+WSVG IFAE++ R P PG + ++Q+ + +G+ ++D + +
Sbjct: 210 NYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQESDIRFIDNPKARRF 269
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
I+ P L + A A++L+ M++ +P KR L Y L +P
Sbjct: 270 IKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDALLHPYMAGLFDP 325
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 170 bits (430), Expect = 3e-42
Identities = 92/291 (31%), Positives = 152/291 (51%), Gaps = 6/291 (2%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y GEG+Y +V K TGR +A+K+ S + A+RE+K L++L+H
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPAD---IKSWILMTLRGVHHC 123
N++ L++V LV EF+ I+ D + + D ++ ++ + G+ C
Sbjct: 61 ENLVNLLEVCKKKKRWYLVFEFVD---HTILDDLELFPNGLDYQVVQKYLFQIINGIGFC 117
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H + I+HRD+KP N+L++ G +K+ DFG AR +A+P E+ T V TRWYRAPELL G
Sbjct: 118 HSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDV 177
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y AVD+W++G + E+ + P PG D+DQ+ LG + +
Sbjct: 178 KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAG 237
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
+++ RE L RR+ +E ++L + ++P KR + L +FQ
Sbjct: 238 VRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQ 288
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 169 bits (429), Expect = 4e-42
Identities = 104/293 (35%), Positives = 160/293 (54%), Gaps = 16/293 (5%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDV 75
G G +V T +A+K+I T F + ++ LRE+K L+ H N++ + DV
Sbjct: 67 GRGACGIVCSAVDSETNEKVAIKKI-TQVFDNTIEAKRTLREIKLLRHFDHENIVAIRDV 125
Query: 76 FM-----ANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
+ + +++ +V E + DL +K + + ++ LRG+ + H +LH
Sbjct: 126 ILPPQRDSFEDVYIVNELMEFDLYRTLKSDQELTKDHGMY-FMYQILRGLKYIHSANVLH 184
Query: 131 RDLKPNNLLLAPDGQLKIADFGLARLMASPQE-ILTSNVVTRWYRAPELLFGAKHYTSAV 189
RDLKP+NLLL+ LKI DFGLAR A+P+ ++T VVTRWYRAPELL G+ YT+A+
Sbjct: 185 RDLKPSNLLLSTQCDLKICDFGLAR--ATPESNLMTEYVVTRWYRAPELLLGSSDYTAAI 242
Query: 190 DIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK--IQIY 247
D+WSVG IF E+M R P PGKD V+Q+ + +GTP++ E+ S S Y K I+
Sbjct: 243 DVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSE---EELGSLSEYAKRYIRQL 299
Query: 248 PPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
P R+ +F A++L+ M+ +PK+R + L Y + T
Sbjct: 300 PTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEALAHPYLSSFHDIT 352
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 169 bits (428), Expect = 5e-42
Identities = 103/307 (33%), Positives = 159/307 (51%), Gaps = 15/307 (4%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
+ D + K + G+GTY+ VY T + +A+K+++ + RE+ L+ L
Sbjct: 142 SADSFEKLEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMAREIIILRRLN 201
Query: 66 HVNVIELVDVFM--ANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H NV++L + + A+ ++ L+ E++ DL + I FS A L G+ HC
Sbjct: 202 HPNVMKLEGLIISKASGSMYLIFEYMDHDLAGLASTPGIKFSQAQ------QLLLGLEHC 255
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQ-EILTSNVVTRWYRAPELLFGA 182
H +LHRD+K +NLLL + LKI DFGL+ + + LTS VVT WYR PELL G+
Sbjct: 256 HSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRKQPLTSRVVTLWYRPPELLLGS 315
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
Y VD+WS G I AEL P LPG+ +V+Q++ F+ G+P++ W S
Sbjct: 316 TDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWRR----SRLR 371
Query: 243 KIQIYPP--PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
I+ P P + + F +AL L+ ++ + P R A LQS++F P P+
Sbjct: 372 HATIFKPQHPYKRCVADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEFFTTKPFPS 431
Query: 301 LPQDLPK 307
P LP+
Sbjct: 432 EPSSLPR 438
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 169 bits (427), Expect = 6e-42
Identities = 97/313 (30%), Positives = 164/313 (51%), Gaps = 18/313 (5%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
VD + + GEGTY VY T +A+K+++ K+G ++A+RE+K L++L H
Sbjct: 801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNH 860
Query: 67 VNVIELVDVFMANDN----------LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMT 116
N++ L ++ + LV E++ DL +++ + F+ + S +
Sbjct: 861 RNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQL 920
Query: 117 LRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASP--QEILTSNVVTRWYR 174
L G+++CH+ LHRD+K +N+L+ G++K+ADFGLARL + + T+ V+T WYR
Sbjct: 921 LDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYR 980
Query: 175 APELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE 234
PELL G + Y ++D+WS G I EL ++ P ++ Q+ + G+P A WP
Sbjct: 981 PPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPN 1040
Query: 235 VSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
V ++ ++ R LR F AL+L+ M+ ++P KR A L+S + +
Sbjct: 1041 VIKLPLFHTLK-QKKTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLR 1099
Query: 295 -----ELPEPTLP 302
E+P P LP
Sbjct: 1100 KINPDEMPTPQLP 1112
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 168 bits (425), Expect = 1e-41
Identities = 106/290 (36%), Positives = 151/290 (51%), Gaps = 16/290 (5%)
Query: 17 GEGTYAVVYLGTK-KSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK---HVNVIEL 72
GEG Y V+ K+ GR +A+K ++ ++G+ +S +REV L+ L+ H NV+ L
Sbjct: 20 GEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRL 79
Query: 73 VDVFMAN-----DNLNLVLEFLPADLEIIIKDTSIMFSPAD-IKSWILMTLRGVHHCHRN 126
DV + L LV E + DL + P + IK + LRG+ H +
Sbjct: 80 FDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSH 139
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
++HRDLKP N+L+ GQ+K+ADFGLAR+ S Q LTS VVT WYRAPE+L + Y
Sbjct: 140 RVVHRDLKPQNILVTSSGQIKLADFGLARIY-SFQMALTSVVVTLWYRAPEVLLQSS-YA 197
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ VD+WSVG IFAE+ R P G DVDQ+ +G P + DWP + Q
Sbjct: 198 TPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPR----QA 253
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+ S + + + E +L+ + NP KR A L YFQ+L
Sbjct: 254 FHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 167 bits (424), Expect = 1e-41
Identities = 96/241 (39%), Positives = 140/241 (57%), Gaps = 5/241 (2%)
Query: 55 LREVKFLQELKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWIL 114
LREVK L+ + H N+++L +V ND L V E++ +L ++KD +F+ ADIK+W
Sbjct: 14 LREVKSLRRMNHPNIVKLKEVIRENDILYFVFEYMECNLYQLMKDRQKLFAEADIKNWCF 73
Query: 115 MTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLAR-LMASPQEILTSNVVTRWY 173
+G+ + H+ HRDLKP NLL++ D +KIADFGLAR + +SP T V TRWY
Sbjct: 74 QVFQGLSYMHQRGYFHRDLKPENLLVSKD-IIKIADFGLAREVNSSPP--FTEYVSTRWY 130
Query: 174 RAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWP 233
RAPE+L + YTS VD+W++G I AEL+ P PG + D+I +GTPT+ W
Sbjct: 131 RAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICSVIGTPTEETWL 190
Query: 234 EVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
E + +N Q +P L +A+E+A+ LI + +P R A + LQ +F
Sbjct: 191 EGLNLANTINYQ-FPQLPGVPLSSLMPSASEDAINLIERLCSWDPSSRPTAAEVLQHPFF 249
Query: 294 Q 294
Q
Sbjct: 250 Q 250
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 167 bits (424), Expect = 1e-41
Identities = 102/277 (36%), Positives = 150/277 (53%), Gaps = 9/277 (3%)
Query: 26 LGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDVFMAND---- 80
L T IA+K+I + F + +D LRE+K L+ L+H NV+ + D+
Sbjct: 56 LSVDSETHEEIAIKKIGKA-FDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDF 114
Query: 81 -NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHRDLKPNNLL 139
++ +V E + DL II+ + + + ++ LRG+ + H +LHRDLKP+NLL
Sbjct: 115 VDVYIVFELMDTDLHQIIRSNQSL-NDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLL 173
Query: 140 LAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFA 199
L + LKI DFGLAR S E +T VVTRWYRAPELL + YTSA+D+WSVG IFA
Sbjct: 174 LNSNCDLKITDFGLART-TSETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFA 232
Query: 200 ELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPSREELRRRF 259
E+M R P PGKD V Q+ + +G+P A + S + ++ P R+ RF
Sbjct: 233 EIMTREPLFPGKDYVHQLKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARF 292
Query: 260 IAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+ A++L+ M++ +P KR + L Y L
Sbjct: 293 PSMNSTAIDLLEKMLVFDPVKRITVEEALCYPYLSAL 329
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 167 bits (423), Expect = 2e-41
Identities = 105/307 (34%), Positives = 161/307 (52%), Gaps = 19/307 (6%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVN 68
D+ + GEG Y VV T K TG +A+K+I+ K + LRE+K L+ KH N
Sbjct: 12 DFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFD-KPLFALRTLREIKILKHFKHEN 70
Query: 69 VIELVDVFMAN--DNLN---LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
+I + ++ + +N N ++ E + DL +I ++ M S I+ +I TLR V
Sbjct: 71 IITIFNIQRPDSFENFNEVYIIQELMQTDLHRVI--STQMLSDDHIQYFIYQTLRAVKVL 128
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLM----------ASPQEILTSNVVTRWY 173
H + ++HRDLKP+NLL+ + LK+ DFGLAR++ Q +T V TRWY
Sbjct: 129 HGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWY 188
Query: 174 RAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTP-TDADW 232
RAPE++ + Y+ A+D+WS G I AEL LR P PG+D Q+ + F +GTP +D D
Sbjct: 189 RAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDL 248
Query: 233 PEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
+ S I+ P L + F ++L+ M++ +P KR A + L+ Y
Sbjct: 249 RCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPY 308
Query: 293 FQELPEP 299
Q +P
Sbjct: 309 LQTYHDP 315
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 167 bits (423), Expect = 2e-41
Identities = 104/296 (35%), Positives = 156/296 (52%), Gaps = 11/296 (3%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLD-MSALREVKFLQELKHVN 68
Y K G G Y VV T +A+K+I + F++ +D + LRE+K L+ ++H N
Sbjct: 32 YVPIKPIGRGAYGVVCSSINSETNERVAIKKIH-NVFENRIDALRTLRELKLLRHVRHEN 90
Query: 69 VIELVDVFMANDNLN-----LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
VI L DV + + LV E + +DL IIK + + S K ++ LRG+ +
Sbjct: 91 VISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIKSSQSL-SDDHCKYFLFQLLRGLKYL 149
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H ILHRDLKP NLL+ + LKI DFGLAR ++ +T VVTRWYRAPELL
Sbjct: 150 HSANILHRDLKPGNLLVNANCDLKICDFGLARTY---EQFMTEYVVTRWYRAPELLLCCD 206
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
+Y +++D+WSVG IFAE++ R P PG + ++Q+ + +G+ D D + +
Sbjct: 207 NYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQDWDLQFIDNQKARRF 266
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
I+ P + A A++L+ M++ +P KR L Y + L EP
Sbjct: 267 IKSLPFSKGTHFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDALLHPYMEGLLEP 322
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 167 bits (422), Expect = 2e-41
Identities = 93/280 (33%), Positives = 151/280 (53%), Gaps = 3/280 (1%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVF 76
GEG Y VV K T +A+K+ K S+ + + + LRE+K L+ LK N++EL + F
Sbjct: 20 GEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAF 79
Query: 77 MANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHRDLKPN 136
L LV E++ ++ ++++ P +KS+I ++ +H CH+N I+HRD+KP
Sbjct: 80 RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPE 139
Query: 137 NLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFGAKHYTSAVDIWSVG 195
NLL++ + LK+ DFG AR ++ T V TRWYR+PELL GA Y +VD+WSVG
Sbjct: 140 NLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP-YGKSVDMWSVG 198
Query: 196 VIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPSREEL 255
I EL P PG+ ++DQ+ + LG S ++ ++ + L
Sbjct: 199 CILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSL 258
Query: 256 RRRFIAATENA-LELISGMMIMNPKKRWDAVKCLQSQYFQ 294
RR++ + L+L+ ++ ++P R+ +CL FQ
Sbjct: 259 ERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ 298
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 166 bits (420), Expect = 4e-41
Identities = 106/304 (34%), Positives = 151/304 (48%), Gaps = 11/304 (3%)
Query: 2 TLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFL 61
T+ + Y G G Y V TG +AVK++ RE++ L
Sbjct: 16 TIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 62 QELKHVNVIELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILM 115
+ +KH NVI L+DVF +L LV + ADL I+K + + ++ I
Sbjct: 76 KHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKL--TDDHVQFLIYQ 133
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRA 175
LRG+ + H I+HRDLKP+NL + D +LKI DFGLAR + +T V TRWYRA
Sbjct: 134 ILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR---HTDDEMTGYVATRWYRA 190
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEV 235
PE++ HY VDIWSVG I AEL+ PG D +DQ+ + R +GTP ++
Sbjct: 191 PEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
Query: 236 SSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
SS S N IQ + FI A A++L+ M++++ KR A + L YF +
Sbjct: 251 SSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQ 310
Query: 296 LPEP 299
+P
Sbjct: 311 YHDP 314
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 166 bits (420), Expect = 4e-41
Identities = 106/310 (34%), Positives = 160/310 (51%), Gaps = 18/310 (5%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y E+ G G Y VV + +A+K+I + L +LREV+ L+EL H N+
Sbjct: 57 YLAEENVGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLHENI 116
Query: 70 IELVDVFMAND----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
I ++D+F A ++ LV++ + DL I+ + + + LRG+ + H
Sbjct: 117 IAVLDMFTAEGAHGKDIYLVMDLMETDLHQILHSRQTLMEQ-HFQYFFYQLLRGLKYLHS 175
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI---------LTSNVVTRWYRAP 176
I+HRDLKP+NLLL D L+IADFG+AR AS + +T V TRWYRAP
Sbjct: 176 AGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVSTRWYRAP 235
Query: 177 ELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS 236
E+LF Y + VD+WS G IFAE++LR PGKD V QI + LG+P + ++
Sbjct: 236 EILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEEEVINRIT 295
Query: 237 SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQ----SQY 292
S + I+ + F A+ A ++S ++ ++P KR+ A + LQ +QY
Sbjct: 296 SDLVRDSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQILQHPFMAQY 355
Query: 293 FQELPEPTLP 302
+ EP P
Sbjct: 356 HNDQYEPLCP 365
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 166 bits (420), Expect = 4e-41
Identities = 105/309 (33%), Positives = 159/309 (50%), Gaps = 16/309 (5%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKH 66
D Y + G G Y V + T +A+K++ F+ + RE++ L+ + H
Sbjct: 23 DIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKL-ARPFQSAVHAKRTYRELRLLKHMDH 81
Query: 67 VNVIELVDVFM---ANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTL 117
NVI L+D+F AN +L LV + ADL II+ + S ++ + L
Sbjct: 82 ENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHL--SDDHVQFLVYQIL 139
Query: 118 RGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPE 177
RG+ + H ++HRDLKP+N+ + D +L+I DFGLAR + +T V TRWYRAPE
Sbjct: 140 RGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR---PTENEMTGYVATRWYRAPE 196
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS 237
++ HY VDIWSVG I AEL+ R PG D + Q+N+ LGTP ++SS
Sbjct: 197 IMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISS 256
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
S + IQ PP + F A A++L+ M+ ++ +KR A + L Y ++
Sbjct: 257 ESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYA 316
Query: 298 EPTLPQDLP 306
EP++ Q P
Sbjct: 317 EPSVEQTSP 325
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 165 bits (418), Expect = 7e-41
Identities = 101/300 (33%), Positives = 158/300 (52%), Gaps = 13/300 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
YT+ + GEG Y +V +A+K+I + + + LRE++ L +H NV
Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRT-LREIQILLRFRHENV 100
Query: 70 IELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
I + D+ A+ ++ +V + + DL ++K + S I ++ LRG+ + H
Sbjct: 101 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQL--SNDHICYFLYQILRGLKYIH 158
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE----ILTSNVVTRWYRAPELLF 180
+LHRDLKP+NLL+ LKI DFGLAR+ A P+ LT V TRWYRAPE++
Sbjct: 159 SANVLHRDLKPSNLLINTTCDLKICDFGLARI-ADPEHDHTGFLTEYVATRWYRAPEIML 217
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+K YT ++DIWSVG I AE++ P PGK +DQ+N LG+P+ D + +
Sbjct: 218 NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKA 277
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
N +Q P ++ + F + AL+L+ M+ NP KR + L Y ++ +PT
Sbjct: 278 RNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPT 337
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 165 bits (417), Expect = 9e-41
Identities = 99/290 (34%), Positives = 151/290 (51%), Gaps = 11/290 (3%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVF 76
G G Y V +G +A+K+ RE++ L+ + H N+I+L+DVF
Sbjct: 42 GTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVF 101
Query: 77 MANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
N+N+N V + ADL I+K + + I+ + LRG+ + H I+H
Sbjct: 102 TPNENVNDIEDVYFVSMLMGADLSNILKIQRL--NDDHIQFLVYQILRGLKYIHSADIIH 159
Query: 131 RDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVD 190
RDLKP+N+ + D +LKI DFGLAR S +T V TRWYRAPE++ HYT VD
Sbjct: 160 RDLKPSNIAVNEDCELKILDFGLARQTDSE---MTGYVATRWYRAPEIMLNWMHYTQTVD 216
Query: 191 IWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPP 250
+WSVG I AEL+ PG D +DQ+ GTP + ++SS N I+ P
Sbjct: 217 VWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKM 276
Query: 251 SREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
+R + +R F AT A++L+ M+ ++P +R A + ++ +Y + T
Sbjct: 277 TRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYLAAYHDET 326
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 164 bits (415), Expect = 2e-40
Identities = 104/300 (34%), Positives = 158/300 (52%), Gaps = 20/300 (6%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGR--------SIAVKEIKTSQFKDGLDMSALREV 58
++ YT K+ G+GT+ V+ K T +A+K +K F + LREV
Sbjct: 1 MERYTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMKKKYFS-WEECVNLREV 59
Query: 59 KFLQELKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLR 118
K L + H N+++L +V ND L V E++ +L ++KD F+ +DI++W +
Sbjct: 60 KSLSRMNHPNIVKLKEVIRENDILYFVFEYMECNLYQLMKDRPKHFAESDIRNWCFQVFQ 119
Query: 119 GVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLAR-LMASPQEILTSNVVTRWYRAPE 177
G+ + H+ HRDLKP NLL++ D +KIAD GLAR + +SP T V TRWYRAPE
Sbjct: 120 GLSYMHQRGYFHRDLKPENLLVSKD-VIKIADLGLAREIDSSPP--YTEYVSTRWYRAPE 176
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPE--- 234
+L + YTS VD+W++G I AEL+ P PG + D+I +G+PT+ W E
Sbjct: 177 VLLQSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETWLEGLN 236
Query: 235 VSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
++S NY +P L A+ +A+ LI + +P R + LQ +FQ
Sbjct: 237 LASVINYQ----FPQFPGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEALQHPFFQ 292
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 164 bits (414), Expect = 2e-40
Identities = 101/302 (33%), Positives = 155/302 (50%), Gaps = 11/302 (3%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D+Y + G G Y VV ++ TG+ +A+K+I + LRE+K L+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 68 NVIELVDVFMAN------DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVH 121
N+I + D+ ++ +VL+ + +DL II + + + ++ ++ LRG+
Sbjct: 113 NIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPL-TLEHVRYFLYQLLRGLK 171
Query: 122 HCHRNFILHRDLKPNNLLLAPDGQLKIADFGLAR-LMASPQE---ILTSNVVTRWYRAPE 177
+ H ++HRDLKP+NLL+ + +LKI DFG+AR L SP E +T V TRWYRAPE
Sbjct: 172 YMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPE 231
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS 237
L+ YT A+D+WSVG IF E++ R PGK+ V Q+ + LGTP+ A V +
Sbjct: 232 LMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGA 291
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
IQ PP + A AL L+ M+ P R A L+ + +
Sbjct: 292 ERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYH 351
Query: 298 EP 299
+P
Sbjct: 352 DP 353
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 164 bits (414), Expect = 2e-40
Identities = 101/302 (33%), Positives = 155/302 (50%), Gaps = 11/302 (3%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
D+Y + G G Y VV ++ TG+ +A+K+I + LRE+K L+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 68 NVIELVDVFMAN------DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVH 121
N+I + D+ ++ +VL+ + +DL II + + + ++ ++ LRG+
Sbjct: 113 NIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPL-TLEHVRYFLYQLLRGLK 171
Query: 122 HCHRNFILHRDLKPNNLLLAPDGQLKIADFGLAR-LMASPQE---ILTSNVVTRWYRAPE 177
+ H ++HRDLKP+NLL+ + +LKI DFG+AR L SP E +T V TRWYRAPE
Sbjct: 172 YMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPE 231
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS 237
L+ YT A+D+WSVG IF E++ R PGK+ V Q+ + LGTP+ A V +
Sbjct: 232 LMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGA 291
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
IQ PP + A AL L+ M+ P R A L+ + +
Sbjct: 292 ERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYH 351
Query: 298 EP 299
+P
Sbjct: 352 DP 353
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 164 bits (414), Expect = 2e-40
Identities = 96/294 (32%), Positives = 150/294 (50%), Gaps = 37/294 (12%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++++ K +K GEGTY VVY K TG +A+K+I+ +G+ +A+RE+ L+EL H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPAD-IKSWILMTLRGVHHCHR 125
N+++L+DV + L LV EFL DL+ + +++ P IKS++ L+G+ CH
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
+ +LHRDLKP NLL+ +G +K+ADFGLAR P T V R
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTRR-------------- 166
Query: 186 TSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQ 245
PG ++DQ+ FR LGTP + WP V+S +Y
Sbjct: 167 --------------------ALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYK--P 204
Query: 246 IYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+P +R++ + E+ L+S M+ +P KR A L +FQ++ +P
Sbjct: 205 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPYKRISAKAALAHPFFQDVTKP 258
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 163 bits (412), Expect = 3e-40
Identities = 99/292 (33%), Positives = 155/292 (52%), Gaps = 6/292 (2%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y+ + G G + +V + TG ++AVK+I L RE+K L+ L+H N+
Sbjct: 20 YSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENI 79
Query: 70 IELVDVFMAN-DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFI 128
I L D+F++ +++ V E L DL ++ TS I+ ++ LRG+ H +
Sbjct: 80 ISLSDIFISPFEDIYFVTELLGTDLHRLL--TSRPLETQFIQYFLYQILRGLKFVHSAGV 137
Query: 129 LHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSA 188
+HRDLKP+N+L+ + LKI DFGLAR+ PQ +T V TR+YRAPE++ + Y
Sbjct: 138 IHRDLKPSNILINENCDLKICDFGLARIQ-DPQ--MTGYVSTRYYRAPEIMLTWQKYNVE 194
Query: 189 VDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYP 248
VDIWS G IFAE++ P PG+D V+Q ++ LGTP + S + +Q P
Sbjct: 195 VDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICSKNTLRFVQSLP 254
Query: 249 PPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
+ +F A +A++L+ M++ +P+KR A L Y +PT
Sbjct: 255 QKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAADALAHNYLAPYHDPT 306
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 163 bits (412), Expect = 3e-40
Identities = 102/303 (33%), Positives = 154/303 (50%), Gaps = 16/303 (5%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKH 66
+ Y + G+G Y V + T +A+K++ F+ + RE++ L+ + H
Sbjct: 22 ETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKL-ARPFQSAVHAKRTYRELRLLKHMDH 80
Query: 67 VNVIELVDVFMAN---DNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTL 117
NVI L+DVF D+L+ +V + ADL II+ + S ++ + L
Sbjct: 81 ENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKL--SDDHVQFLVYQIL 138
Query: 118 RGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPE 177
RG+ + H ++HRDLKP+N+ + D +L+I DFGLAR S +T V TRWYRAPE
Sbjct: 139 RGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESE---MTGYVATRWYRAPE 195
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS 237
++ HY DIWSVG I AEL+ PG D + Q+N+ LGTP D +SS
Sbjct: 196 IMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISS 255
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
S N I+ P R R F A A++L+ M+ ++ KR A + L Y ++
Sbjct: 256 ESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYH 315
Query: 298 EPT 300
+PT
Sbjct: 316 DPT 318
>Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 240
Score = 162 bits (410), Expect = 6e-40
Identities = 101/290 (34%), Positives = 143/290 (48%), Gaps = 57/290 (19%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++DYTK +K GEGTY VVY G K+TG+ +A+K+I+ ++G+ +A+RE+ L+EL+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N++ L DV M + L L+ EFL D+K +
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSM----------------DLKKY-------------- 90
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
L P GQ D L + VVT WYR+PE+L G+ Y+
Sbjct: 91 -----------LDSIPPGQYM--DSSLVK------------VVTLWYRSPEVLLGSARYS 125
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
+ VDIWS+G IFAEL + P G ++DQ+ FRALGTP + WPEV S +Y
Sbjct: 126 TPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK--NT 183
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+P L EN L+L+S M+I +P KR L YF +L
Sbjct: 184 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 233
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 162 bits (410), Expect = 6e-40
Identities = 107/294 (36%), Positives = 158/294 (53%), Gaps = 14/294 (4%)
Query: 14 KKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELV 73
++ G+GT VY T +AVK++K +F + LREVK L++L H ++I+L
Sbjct: 16 EELGDGTCGSVYKAVNLETYEVVAVKKMKR-KFYYWEECVNLREVKALRKLNHPHIIKLK 74
Query: 74 DVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHRDL 133
++ ++ L + E + +L I+K+ FS +I+S++ L+G+ H H+N HRDL
Sbjct: 75 EIVREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHMHKNGYFHRDL 134
Query: 134 KPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWS 193
KP NLL+ + LKIADFGLAR +AS T V TRWYRAPE+L + YT AVD+W+
Sbjct: 135 KPENLLVT-NNILKIADFGLAREVASMPPY-TEYVSTRWYRAPEVLLQSSLYTPAVDMWA 192
Query: 194 VGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPSRE 253
VG I AEL P PG+ ++DQ+ LG P +PE S S I S
Sbjct: 193 VGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSI------SHT 246
Query: 254 ELRRRFIA-----ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLP 302
E + IA A A++LI+ + +P KR A + L +F + + P
Sbjct: 247 EFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFFSMATQASYP 300
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 162 bits (410), Expect = 6e-40
Identities = 107/298 (35%), Positives = 160/298 (52%), Gaps = 15/298 (5%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK--- 65
+Y + GEG Y VY TG +A+K+++ S ++G+ MS LRE+ L++L
Sbjct: 25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASN 84
Query: 66 HVNVIELVDV--FMANDN---LNLVLEFLPADL-EIIIKDTSIMFSPADIKSWILMTLRG 119
H N+++L +V F+ D + LV E + DL ++I + SP I+ L G
Sbjct: 85 HANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTG 144
Query: 120 VHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELL 179
V H + I+HRDLKP NLL++ G LKIADFGLA+ S + LTS VVT WYRAPE+L
Sbjct: 145 VDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAPEVL 203
Query: 180 FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
A+ Y S VDIWS I E+ R PG + +Q++ F G PT+ WP+ S +
Sbjct: 204 L-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVA 262
Query: 240 NYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
+ Q +P ++ + A +L++ M+ + R A+ CL+ YFQ+ P
Sbjct: 263 LEHFPQRHPKRPKDFCPH----LCKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEP 316
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 162 bits (409), Expect = 8e-40
Identities = 102/300 (34%), Positives = 154/300 (51%), Gaps = 13/300 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
YT GEG Y +V +A+K+I + + + LRE+K L +H N+
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRT-LREIKILLRFRHENI 83
Query: 70 IELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
I + D+ A ++ +V + + DL ++K + S I ++ LRG+ + H
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHL--SNDHICYFLYQILRGLKYIH 141
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE----ILTSNVVTRWYRAPELLF 180
+LHRDLKP+NLLL LKI DFGLAR+ A P LT V TRWYRAPE++
Sbjct: 142 SANVLHRDLKPSNLLLNTTCDLKICDFGLARV-ADPDHDHTGFLTEYVATRWYRAPEIML 200
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+K YT ++DIWSVG I AE++ P PGK +DQ+N LG+P+ D + +
Sbjct: 201 NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKA 260
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
N + P ++ R F A AL+L+ M+ NP KR + + L Y ++ +P+
Sbjct: 261 RNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPS 320
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 161 bits (408), Expect = 1e-39
Identities = 98/296 (33%), Positives = 147/296 (49%), Gaps = 17/296 (5%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
S D+ K +K GEGTY V+ T +A+K ++ DG+ SALRE+ L+EL
Sbjct: 70 SREDEQKKLEKIGEGTYGTVFKAKNWETHEIVALKWVRLDDNDDGVPSSALREICLLKEL 129
Query: 65 KHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
KH N++ L D+ ++ L LV +F L+ + P +KS++ L+G+ CH
Sbjct: 130 KHKNIVRLHDLLHSDKKLTLVFKFCHQHLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 189
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKH 184
+L RDLKP NLL+ +G+LK+ADFGL+R P + FGAK
Sbjct: 190 SRNVLRRDLKPQNLLINRNGELKLADFGLSRAFGIP--------------ICYVFFGAKL 235
Query: 185 YTSAVDIWSVGVIFAELM-LRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
Y++++D+WS G IFAEL P PG D DQ+ F LG T WP ++ +Y
Sbjct: 236 YSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFWLLGMLTKEQWPSMTKLPDYKL 295
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+Y P+ L + +L+ ++ NP + A + LQ YF + P
Sbjct: 296 YPLY--PATTSLVNIVPKLSATGRDLLQNLLKCNPCQCISAEEALQYPYFSDFCPP 349
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 161 bits (407), Expect = 1e-39
Identities = 95/282 (33%), Positives = 150/282 (52%), Gaps = 9/282 (3%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDV 75
G G +V TG +A+K+I + F + +D LRE+K L+ + H NVI + D+
Sbjct: 82 GRGACGIVCAAVNSVTGEKVAIKKIGNA-FDNIIDAKRTLREIKLLRHMDHENVITIKDI 140
Query: 76 FMAN-----DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
+++ +V E + DL+ I++ + S + + LRG+ + H ILH
Sbjct: 141 VRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSD-QCRFLVYQLLRGLKYVHSANILH 199
Query: 131 RDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVD 190
RDL+P+N+LL +LKI DFGLAR S + +T VVTRWYRAPELL YT+A+D
Sbjct: 200 RDLRPSNVLLNSKNELKIGDFGLART-TSDTDFMTEYVVTRWYRAPELLLNCSEYTAAID 258
Query: 191 IWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPP 250
IWSVG I E+M P PGKD V Q+ + +G+P ++ + S + ++ P
Sbjct: 259 IWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSSLGFLRSDNARRYVRQLPRY 318
Query: 251 SREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
+++ RF A++L+ M++ +P +R + L Y
Sbjct: 319 PKQQFAARFPKMPTTAIDLLERMLVFDPNRRISVDEALGHAY 360
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 160 bits (405), Expect = 2e-39
Identities = 99/292 (33%), Positives = 149/292 (50%), Gaps = 11/292 (3%)
Query: 14 KKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELV 73
+ G G Y V + +AVK++ RE++ L+ LKH NVI L+
Sbjct: 28 RPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLL 87
Query: 74 DVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNF 127
DVF ++ LV + ADL I+K ++ S ++ + LRG+ + H
Sbjct: 88 DVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQAL--SDEHVQFLVYQLLRGLKYIHSAG 145
Query: 128 ILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTS 187
I+HRDLKP+N+ + D +L+I DFGLAR E +T V TRWYRAPE++ HY
Sbjct: 146 IIHRDLKPSNVAVNEDCELRILDFGLAR---QADEEMTGYVATRWYRAPEIMLNWMHYNQ 202
Query: 188 AVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIY 247
VDIWSVG I AEL+ PG D +DQ+ +GTP+ ++SS IQ
Sbjct: 203 TVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSL 262
Query: 248 PPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
PP +++L F A A++L+ M++++ +R A + L YF + +P
Sbjct: 263 PPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDP 314
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 160 bits (404), Expect = 3e-39
Identities = 104/290 (35%), Positives = 157/290 (53%), Gaps = 28/290 (9%)
Query: 37 AVKEIKTSQ------FKDGLDMSALREVKFLQELKHVNVIELVDVFMANDNLNLVLEFLP 90
A+K+ KT + G+ SA RE+ +EL + ++ LV++F+ +++V E+
Sbjct: 181 AIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAE 240
Query: 91 ADLEIIIKDTSI----MFSPADIKSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQL 146
DL II S M P ++S + L GV + H+N++LHRDLKP N+++ DG +
Sbjct: 241 HDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCV 300
Query: 147 KIADFGLARLMASPQEILTSN---VVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELML 203
KI D GLAR + + L + VVT WYRAPELL GA+HYT AVD+WSVG IFAEL+
Sbjct: 301 KIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIG 360
Query: 204 RIPYLPGKD-----------DVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPSR 252
P G++ V+Q+ LGTP WP + + Y++I + P R
Sbjct: 361 LQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKF-PKYR 419
Query: 253 EELRRRFIAA---TENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+ L + +A ++AL L+ ++ +P KR DA L+ +YF E P
Sbjct: 420 DNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIP 469
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 160 bits (404), Expect = 3e-39
Identities = 100/313 (31%), Positives = 157/313 (49%), Gaps = 15/313 (4%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHV 67
++Y G+G Y VV K +G +AVK+I + LRE+K L+ +H
Sbjct: 37 EEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPV-FCLRTLREIKLLRHFRHE 95
Query: 68 NVIELVDV-----FMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHH 122
N+I ++D+ + +++ +V E + DL +I+ + S + + LR +
Sbjct: 96 NIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQPL--SDDHCQYFTYQILRALKA 153
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASP---QEILTSNVVTRWYRAPELL 179
H ++HRDLKP+NLLL + LK+ADFGLAR + +T V TRWYRAPE++
Sbjct: 154 MHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPEIM 213
Query: 180 FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
+ Y+ A+D+WS G I AE++ P PGKD QI + LGTPT D+ + S
Sbjct: 214 LSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKSAR 273
Query: 240 NYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQ----SQYFQE 295
I+ P + + F A+ +A++L+ ++ NP KR A + L+ + Y
Sbjct: 274 ARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALKHPYVAAYHDA 333
Query: 296 LPEPTLPQDLPKL 308
EPT P L
Sbjct: 334 SDEPTASPMPPNL 346
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 160 bits (404), Expect = 3e-39
Identities = 97/299 (32%), Positives = 154/299 (51%), Gaps = 13/299 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y GEG Y +V T +A+K+I + + + LRE+K L KH N+
Sbjct: 96 YVNLSYIGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRT-LREIKILNRFKHENI 154
Query: 70 IELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
I + ++ + ++ +V + DL ++K + S + ++ LRG+ + H
Sbjct: 155 INIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKL--SNDHVCYFLYQILRGLKYIH 212
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE----ILTSNVVTRWYRAPELLF 180
+LHRDLKP+NLLL LKI DFGLAR+ PQ LT V TRWYRAPE++
Sbjct: 213 SANVLHRDLKPSNLLLNTTCDLKICDFGLARV-TDPQTDHTGFLTEYVATRWYRAPEIML 271
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+K YT ++D+WSVG I AE++ P PGK +DQ+N+ +G+P++AD + +
Sbjct: 272 NSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDKA 331
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+ + P ++ R + A AL+L+ M+ NP R D + L Y ++ +P
Sbjct: 332 RSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLEQYYDP 390
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 160 bits (404), Expect = 3e-39
Identities = 97/299 (32%), Positives = 154/299 (51%), Gaps = 13/299 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y GEG Y +V T +A+K+I + + + LRE+K L KH N+
Sbjct: 28 YVNLSYIGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRT-LREIKILNRFKHENI 86
Query: 70 IELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
I + ++ + ++ +V + DL ++K + S + ++ LRG+ + H
Sbjct: 87 INIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKL--SNDHVCYFLYQILRGLKYIH 144
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE----ILTSNVVTRWYRAPELLF 180
+LHRDLKP+NLLL LKI DFGLAR+ PQ LT V TRWYRAPE++
Sbjct: 145 SANVLHRDLKPSNLLLNTTCDLKICDFGLARV-TDPQTDHTGFLTEYVATRWYRAPEIML 203
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+K YT ++D+WSVG I AE++ P PGK +DQ+N+ +G+P++AD + +
Sbjct: 204 NSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDKA 263
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+ + P ++ R + A AL+L+ M+ NP R D + L Y ++ +P
Sbjct: 264 RSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLEQYYDP 322
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 159 bits (403), Expect = 4e-39
Identities = 101/300 (33%), Positives = 153/300 (50%), Gaps = 13/300 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
YT GEG Y +V +A+K+I + + + LRE+K L +H N+
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRT-LREIKILLRFRHENI 83
Query: 70 IELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
I + D+ A ++ +V + + DL ++K + S I ++ LRG+ + H
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHL--SNDHICYFLYQILRGLKYIH 141
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE----ILTSNVVTRWYRAPELLF 180
+LHRDLKP+NLLL LKI DFGLAR+ A P LT V TRWYRAPE++
Sbjct: 142 SANVLHRDLKPSNLLLNTTCDLKICDFGLARV-ADPDHDHTGFLTEYVATRWYRAPEIML 200
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+K YT ++DIWSVG I AE++ P PGK +DQ+ LG+P+ D + +
Sbjct: 201 NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPSQEDLNCIINLKA 260
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
N + P ++ R F A AL+L+ M+ NP KR + + L Y ++ +P+
Sbjct: 261 RNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPS 320
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 159 bits (401), Expect = 6e-39
Identities = 97/296 (32%), Positives = 150/296 (49%), Gaps = 12/296 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y G G Y V K +G +A+K++ + A RE+ L+ ++H NV
Sbjct: 25 YVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENV 84
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
I L+DVF +L LV+ F+ DL+ I+ + FS I+ + L+G+ +
Sbjct: 85 IGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM---GMEFSEEKIQYLVYQMLKGLKYI 141
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H ++HRDLKP NL + D +LKI DFGLAR + +T VVTRWYRAPE++
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAE---MTGYVVTRWYRAPEVILSWM 198
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
HY VDIWSVG I AE++ GKD +DQ+ + G P +++ + +
Sbjct: 199 HYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSY 258
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
IQ P R++ + F A+ A +L+ M+ ++ KR A + L +F+ +P
Sbjct: 259 IQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDP 314
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 159 bits (401), Expect = 6e-39
Identities = 105/298 (35%), Positives = 148/298 (49%), Gaps = 18/298 (6%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDG---LDMSALREVKFLQELK- 65
Y + G G Y VY +G +A+K ++ G L +S +REV L+ L+
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 66 --HVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPAD-IKSWILMTL 117
H NV+ L+DV + + LV E + DL + PA+ IK + L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 118 RGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPE 177
RG+ H N I+HRDLKP N+L+ G +K+ADFGLAR+ S Q LT VVT WYRAPE
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIY-SYQMALTPVVVTLWYRAPE 184
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSS 237
+L + Y + VD+WSVG IFAE+ R P G + DQ+ F +G P + DWP S
Sbjct: 185 VLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVS 243
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+PP ++ E+ +L+ M+ NP KR A + LQ Y +
Sbjct: 244 LPR----GAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHK 297
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 159 bits (401), Expect = 6e-39
Identities = 103/294 (35%), Positives = 150/294 (50%), Gaps = 8/294 (2%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVN 68
D ++ G G + VV+ T GR +A+K++ RE+K L KH N
Sbjct: 39 DVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHEN 98
Query: 69 VIELVDVFMAN-----DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
V+ +D+ + ++ E L +DL II + S IK ++ LRG+ +
Sbjct: 99 VLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHL-SADHIKVFLYQILRGLKYL 157
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQ-EILTSNVVTRWYRAPELLFGA 182
H ILHRD+KP NLL+ + LKI DFGLAR+ Q + +T VVT++YRAPE+L GA
Sbjct: 158 HSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGA 217
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
+HY+SAVD+WSVG IF EL+ R ++ V Q+ + LGTPT D + +
Sbjct: 218 RHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTH 277
Query: 243 KIQIYP-PPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
++ P PPS L AT A+ L+ M++ +P KR L Y E
Sbjct: 278 MLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDE 331
>CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 489
Score = 158 bits (399), Expect = 1e-38
Identities = 107/349 (30%), Positives = 167/349 (47%), Gaps = 56/349 (16%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTK-----------KSTGRSIAVKEIKTSQFKDGLDMSAL 55
V Y K K G+GT+ V G K K+TGR +A+K+I K+G ++AL
Sbjct: 82 VSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITAL 141
Query: 56 REVKFLQELKHVNVIELVDVFMANDN----------LNLVLEFLPADLEIIIKDTSIMFS 105
REVK L++LKH N+ +L++V A LV+ DL ++ + I S
Sbjct: 142 REVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMS 201
Query: 106 PADIKSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLM------AS 159
IK+ + + G++ HR+ ILHRD+K N+L++ DG LK+ADFGLAR A
Sbjct: 202 LVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAG 261
Query: 160 PQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINV 219
P+ + T+ VVT WYR PELL G + Y + +D+W G I AE+ R P + G + Q+ +
Sbjct: 262 PRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQL 321
Query: 220 TFRALGTPTDADWP-------------EVSSFSNYNKIQIYP----------------PP 250
G+ WP E +S K +I P P
Sbjct: 322 ISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDP 381
Query: 251 SREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+ +++ A ++AL L+ ++ ++P KR + + +F + P P
Sbjct: 382 FGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWFFKDPVP 430
>CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 456
Score = 158 bits (399), Expect = 1e-38
Identities = 107/349 (30%), Positives = 167/349 (47%), Gaps = 56/349 (16%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTK-----------KSTGRSIAVKEIKTSQFKDGLDMSAL 55
V Y K K G+GT+ V G K K+TGR +A+K+I K+G ++AL
Sbjct: 82 VSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITAL 141
Query: 56 REVKFLQELKHVNVIELVDVFMANDN----------LNLVLEFLPADLEIIIKDTSIMFS 105
REVK L++LKH N+ +L++V A LV+ DL ++ + I S
Sbjct: 142 REVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMS 201
Query: 106 PADIKSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLM------AS 159
IK+ + + G++ HR+ ILHRD+K N+L++ DG LK+ADFGLAR A
Sbjct: 202 LVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAG 261
Query: 160 PQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINV 219
P+ + T+ VVT WYR PELL G + Y + +D+W G I AE+ R P + G + Q+ +
Sbjct: 262 PRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQL 321
Query: 220 TFRALGTPTDADWP-------------EVSSFSNYNKIQIYP----------------PP 250
G+ WP E +S K +I P P
Sbjct: 322 ISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDP 381
Query: 251 SREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+ +++ A ++AL L+ ++ ++P KR + + +F + P P
Sbjct: 382 FGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWFFKDPVP 430
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 157 bits (398), Expect = 1e-38
Identities = 103/304 (33%), Positives = 146/304 (47%), Gaps = 11/304 (3%)
Query: 2 TLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFL 61
T+ + Y G G Y V TG +AVK++ RE++ L
Sbjct: 16 TIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 62 QELKHVNVIELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILM 115
+ +KH NVI L+DVF +L LV + ADL I+K + + ++ I
Sbjct: 76 KHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKL--TDDHVQFLIYQ 133
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRA 175
LRG+ + H I+HRDLKP+NL + D +LKI DFGLAR + +T V TRWYRA
Sbjct: 134 ILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR---HTDDEMTGYVATRWYRA 190
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEV 235
PE++ HY VDIWSVG I AEL+ PG D ++Q+ R GTP +
Sbjct: 191 PEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRM 250
Query: 236 SSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
S N IQ + FI A A++L+ M++++ KR A + L YF +
Sbjct: 251 PSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQ 310
Query: 296 LPEP 299
+P
Sbjct: 311 YHDP 314
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 157 bits (397), Expect = 2e-38
Identities = 90/276 (32%), Positives = 145/276 (51%), Gaps = 1/276 (0%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
+D Y + K GEG+Y VVY + TG+ +A+K+ ++ + ALRE++ L++LKH
Sbjct: 1 MDKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKH 60
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
N++ L++VF N L+LV E + ++ + IK I L + CH +
Sbjct: 61 QNLVGLIEVFKRNRKLHLVFELCDRTVLHELEKNPHGVNDELIKKIIYQLLEALKFCHSH 120
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
+HRD+KP N+ L + Q+K+ DFG AR++ + E+ T V TRWYR+PELL G Y
Sbjct: 121 KCIHRDVKPENIFLTRNDQVKLGDFGFARII-NTTEMYTDYVATRWYRSPELLVGDVQYG 179
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
VDIW+VG ++AEL+ PG+ D+DQ+ + LG + + + I
Sbjct: 180 PPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGLSI 239
Query: 247 YPPPSREELRRRFIAATENALELISGMMIMNPKKRW 282
P E L + A+ L+ + M+P +R+
Sbjct: 240 PEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRF 275
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 156 bits (394), Expect = 4e-38
Identities = 97/307 (31%), Positives = 163/307 (52%), Gaps = 33/307 (10%)
Query: 19 GTYAVVYLGTKKSTG--RSIAVKEIK-------TSQFKDGLDMSALREVKFLQELKHVNV 69
GTY VY ++ R A+K+ K ++ + G+ SA+RE+ +E++H N+
Sbjct: 14 GTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLCREIQHENI 73
Query: 70 IELVDVFMANDNLNLVLEFLPADLEIII----KDTSIMFSPADIKSWILMTLRGVHHCHR 125
+ LV V + + +++V E+ DL II + + P+ +KS + + GV + H
Sbjct: 74 VSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQIINGVAYLHE 133
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSN---VVTRWYRAPELLFGA 182
N+I+HRDLKP N+++ G++KI D GL RL+ P S+ VVT WYRAPELL GA
Sbjct: 134 NWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTIWYRAPELLLGA 193
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDV---DQINVTFRA---------LGTPTDA 230
YT A+D+W++G I+ E++ P G D++ D+ V F++ LGTPT+
Sbjct: 194 HDYTPAIDVWAIGCIYGEMLALSPLFKG-DEIKMEDKKVVPFQSTQMLRIMELLGTPTEE 252
Query: 231 DWPEVSSFSNYNKIQIYPPPSREELRRRFIAATEN----ALELISGMMIMNPKKRWDAVK 286
WP + ++ Y ++ + L ++ +N L+L+ M+ +PK R A +
Sbjct: 253 RWPGLKNYPEYYQLSSFEVRYWNNLLPQWYQTVKNRDPQGLDLLMKMLQYDPKSRITAKQ 312
Query: 287 CLQSQYF 293
L+ +F
Sbjct: 313 ALEHVFF 319
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 155 bits (391), Expect = 9e-38
Identities = 100/302 (33%), Positives = 162/302 (53%), Gaps = 23/302 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
YT K G G++ VV + A+K + + +FK+ RE++ ++ +KH N
Sbjct: 32 YTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKN-------RELQIMRIMKHPN 84
Query: 69 VIELVDVFMAN-DN-----LNLVLEFLPADL---EIIIKDTSIMFSPADIKSWILMTLRG 119
+++L+ + DN LNLVLEF+P + + + ++K +I LR
Sbjct: 85 IVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRS 144
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ + H + I HRD+KP NLLL P+ G LK+ DFG A+++ + + + S + +R+YRAPEL
Sbjct: 145 LAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNV-SYICSRYYRAPEL 203
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA YT A+DIWS G + AELML P PG+ +DQ+ + LGTP+ ++ +
Sbjct: 204 IFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTMNPN 263
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
+ + QI P P R + +AL+L+S M+ P R A + + +F EL
Sbjct: 264 YMEHRFPQIRPQPLSRVFSR---SVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELR 320
Query: 298 EP 299
+P
Sbjct: 321 DP 322
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 154 bits (390), Expect = 1e-37
Identities = 95/292 (32%), Positives = 166/292 (56%), Gaps = 24/292 (8%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVNVIELVDV 75
G G++ VV+ + T +A+K++ + +FK+ RE++ ++ L H+N+I+L
Sbjct: 46 GHGSFGVVFATVIQETNEKVAIKKVLQDKRFKN-------RELEIMKMLSHINIIDLKYF 98
Query: 76 FMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPA---DIKSWILMTLRGVHHCHRNF 127
F D+ LNL+LE++P L ++ +P +IK ++ + +++ H
Sbjct: 99 FYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFA 158
Query: 128 -ILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
+ HRD+KP NLL+ P+ LK+ DFG A+ + P E S + +R+YRAPEL+FGA +Y
Sbjct: 159 NVCHRDIKPQNLLVDPETWSLKLCDFGSAKQL-KPTEPNVSYICSRYYRAPELIFGATNY 217
Query: 186 TSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-SFSNYNKI 244
T+ +DIWS G + AEL+L P PG+ +DQ+ + LGTP+ + ++ ++ +
Sbjct: 218 TNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFP 277
Query: 245 QIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
QI P P L R F + +E ++ ++ +P +R++A++CL S YF EL
Sbjct: 278 QIKPIP----LSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDEL 325
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 154 bits (390), Expect = 1e-37
Identities = 98/307 (31%), Positives = 155/307 (49%), Gaps = 14/307 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + G G Y V TG +A+K++ + A RE++ L+ ++H NV
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
I L+DVF ++ L+ LV+ F+ DL ++K + I+ + L+G+ +
Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKL--GEDRIQFLVYQMLKGLRYI 144
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H I+HRDLKP NL + D +LKI DFGLAR S +T VVTRWYRAPE++
Sbjct: 145 HAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSE---MTGYVVTRWYRAPEVILNWM 201
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
YT VDIWSVG I AE++ G D +DQ+ + GTP + S N
Sbjct: 202 RYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNN 261
Query: 244 IQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQ 303
++ P +++ A+ A+ L+ M++++ ++R A + L YF+ L + +
Sbjct: 262 MKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESLHD---TE 318
Query: 304 DLPKLNK 310
D P++ K
Sbjct: 319 DEPQVQK 325
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 154 bits (389), Expect = 2e-37
Identities = 115/318 (36%), Positives = 167/318 (52%), Gaps = 27/318 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSA-LREVKFLQELKHVN 68
Y ++ G+G+Y VV TG +A+K+I F+ D + LRE+K L+ L+H +
Sbjct: 104 YQIQEVVGKGSYGVVASAVDSHTGERVAIKKIN-DVFEHVSDATRILREIKLLRLLRHPD 162
Query: 69 VIELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
V+E+ + + ++ +V E + +DL +IK + +P + ++ LRG+ +
Sbjct: 163 VVEIKHIMLPPSRREFRDIYVVFELMESDLHQVIKANDDL-TPEHYQFFLYQLLRGLKYV 221
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMAS--PQEIL-TSNVVTRWYRAPELL- 179
H + HRDLKP N+L D +LKI DFGLAR+ + P I T V TRWYRAPEL
Sbjct: 222 HAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPELCG 281
Query: 180 -FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSF 238
F +K YT A+DIWSVG IFAE++L P PGK+ V Q+++ LGTP PE S
Sbjct: 282 SFFSK-YTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPP----PESISR 336
Query: 239 SNYNKIQIYPPPSREE----LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
K + Y R++ +F A AL L+ ++ +PK R A L YF
Sbjct: 337 IRNEKARRYLSSMRKKQPVPFSHKFPKADPLALRLLERLLAFDPKDRASAEDALADPYFS 396
Query: 295 ELP----EPTLPQDLPKL 308
L EPT Q + KL
Sbjct: 397 GLSNSEREPT-TQPISKL 413
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 154 bits (389), Expect = 2e-37
Identities = 97/319 (30%), Positives = 167/319 (51%), Gaps = 20/319 (6%)
Query: 3 LKSTVDD-YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKF 60
L TV+ + K+ G+G Y +V+ T + T ++A+K++ + F+D D REV F
Sbjct: 17 LDQTVESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDA-FRDETDAQRTYREVIF 75
Query: 61 LQELK-HVNVIELVDVFMANDNLN--LVLEFLPADLEIIIKDTSIMFSPADIKSWILM-- 115
L+ + H N++ LVD+F A++NL+ LV EF+ +DL +IK +++ D+ +M
Sbjct: 76 LRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMESDLHNVIKRGNVL---KDVHKRFVMYQ 132
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQ--------EILTSN 167
+ + H ++HRDLKP+N+L+ +LK+ADFGLAR ++S + +LT
Sbjct: 133 LINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDY 192
Query: 168 VVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTP 227
V TRWYRAPE+L +++YT +D+W +G I E++ + P G V+QI +L
Sbjct: 193 VATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNV 252
Query: 228 TDADWPEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVK 286
T D + SF + + R L ++ + L+ ++++NP R A +
Sbjct: 253 TKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKE 312
Query: 287 CLQSQYFQELPEPTLPQDL 305
++ Y + DL
Sbjct: 313 AIRHPYVSRFQYASAEMDL 331
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 152 bits (384), Expect = 6e-37
Identities = 107/301 (35%), Positives = 159/301 (52%), Gaps = 20/301 (6%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y ++ G+G+Y VV TG +A+K+I LRE+K L+ L H +V
Sbjct: 90 YQIQEVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLLHPDV 149
Query: 70 IELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
+E+ + + ++ +V E + +DL +IK + +P + ++ LRG+ + H
Sbjct: 150 VEIKHIMLPPSRREFRDVYVVFELMESDLHQVIKANDDL-TPEHHQFFLYQLLRGLKYVH 208
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLARLMAS--PQEIL-TSNVVTRWYRAPELL-- 179
+ HRDLKP N+L D +LKI DFGLAR+ + P I T V TRWYRAPEL
Sbjct: 209 AANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPELCGS 268
Query: 180 FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
F +K YT A+DIWSVG IFAE++L P PGK+ V Q+++ LGTP PE S
Sbjct: 269 FFSK-YTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPP----PEAISKI 323
Query: 240 NYNKIQIYPPPSREE----LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+K + Y R++ ++F A +AL L+ ++ +PK R A + L YF
Sbjct: 324 RNDKARRYLGNMRKKQPVPFSKKFPKADPSALRLLERLIAFDPKDRPSAEEALADPYFNG 383
Query: 296 L 296
L
Sbjct: 384 L 384
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 152 bits (383), Expect = 8e-37
Identities = 101/298 (33%), Positives = 151/298 (49%), Gaps = 12/298 (4%)
Query: 14 KKAGEGTYAVVYLGTKKSTG--RSIAVKEIKTSQFKDGLDMSALREVKFLQELK-HVNVI 70
K+ G+G Y +V ++ ++A+K+I K L ALRE+K L + H N+
Sbjct: 25 KELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRNHRNIT 84
Query: 71 ELVDVFMAND-NLNLVL---EFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
+ D+ + N N N V E + ADL IIK + + A +S+I L G+ + H
Sbjct: 85 CIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPL-TDAHFQSFIYQILCGLKYIHSA 143
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLAR-LMASPQE---ILTSNVVTRWYRAPELLFGA 182
++HRDLKP NLL+ D +LKI DFGLAR +P+E +T V TRWYRAPE++
Sbjct: 144 NVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYRAPEIMLSF 203
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
Y +D+WSVG I AEL+ P GKD V Q+N+ LGTP + +SS
Sbjct: 204 SSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSHISSSRAQE 263
Query: 243 KIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
++ P F A AL+L++ ++ +P +R L+ Y +P+
Sbjct: 264 YVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDALEHPYLAVWHDPS 321
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 151 bits (381), Expect = 1e-36
Identities = 98/311 (31%), Positives = 163/311 (51%), Gaps = 25/311 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
Y +K G G++ VV+L +T +A+K++ + +FK+ RE++ +++L H N
Sbjct: 36 YYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKN-------RELQIMRKLNHPN 88
Query: 69 VIELVDVFMANDN------LNLVLEFLPADLEIIIKDTSIMFSPAD---IKSWILMTLRG 119
+++L F ++ LNL+LE++P + + + S +K ++ LR
Sbjct: 89 IVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRS 148
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ + H I HRD+KP NLL+ P+ G LK+ DFG A+ + E S + +R+YRAPEL
Sbjct: 149 LAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVR-NEPNVSYICSRYYRAPEL 207
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA +YT+++D+WS G + AEL+L P PG VDQ+ + LGTPT ++ +
Sbjct: 208 IFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPN 267
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL- 296
+ + QI P + R + A++LIS ++ P R Q +F EL
Sbjct: 268 YKEFKFPQIKAHPWNKVFR---VHTPAEAIDLISKIIEYTPTSRPTPQAACQHAFFDELR 324
Query: 297 -PEPTLPQDLP 306
P+ LP P
Sbjct: 325 NPDARLPSGRP 335
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 150 bits (380), Expect = 2e-36
Identities = 102/311 (32%), Positives = 160/311 (50%), Gaps = 19/311 (6%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL-KHVNVIELVDV 75
GEG Y V K +G +A+K+I+ K + + +RE+K L+ +H N+I ++D
Sbjct: 20 GEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRT-IREIKLLRYFHEHENIISILDK 78
Query: 76 F--MANDNLN---LVLEFLPADLEIIIKDTSIMFSPAD---IKSWILMTLRGVHHCHRNF 127
++ D LN LV E + DL+ +I + + FS ++ + LR + H
Sbjct: 79 VRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQ 138
Query: 128 ILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE-------ILTSNVVTRWYRAPELLF 180
++HRD+KP+NLLL + LK+ DFGLAR +AS + +T V TRWYRAPE++
Sbjct: 139 VIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIML 198
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+ YT+A+DIWS G I AE++ P PG+D Q+ + LGTP+ D+ ++ S
Sbjct: 199 TFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRA 258
Query: 241 YNKIQIYP--PPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE 298
I P PP E + ++L+ M+ NP KR A + L+ Y +
Sbjct: 259 KEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHD 318
Query: 299 PTLPQDLPKLN 309
P+ + P LN
Sbjct: 319 PSDEPEYPPLN 329
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 150 bits (380), Expect = 2e-36
Identities = 108/349 (30%), Positives = 162/349 (45%), Gaps = 60/349 (17%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K GEG Y VV + TG +A+K+ RE+K L+ L+H NV
Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNV 108
Query: 70 IELVDVFMAN------DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
+E++DVF + +N+ V + +DL+ I+K + + I+ I LRG+ +
Sbjct: 109 LEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRL--TDEQIQLLIYQVLRGLKYM 166
Query: 124 -HRNF----------------------------ILHRDLKPNNLLLAPDGQLK------- 147
H+NF I+HRDLKP+N+ + ++K
Sbjct: 167 SHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQ 226
Query: 148 ----------IADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVI 197
I DFGLAR + +T V TRWYRAPE++ HYT VD+WSVG I
Sbjct: 227 LSFLILSFFKILDFGLARAQDAE---MTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCI 283
Query: 198 FAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPSREELRR 257
AEL+ P PG D +DQ+ +GTP + W ++ S N I+ P R++
Sbjct: 284 LAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNRSPIIRQDFVT 343
Query: 258 RFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQDLP 306
F A+ ALEL+ M+I++P +R L+ Y +E ++P D P
Sbjct: 344 LFPMASPYALELLEMMLILDPDRRISVSSALRHDYLREY---SVPNDEP 389
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 150 bits (380), Expect = 2e-36
Identities = 84/252 (33%), Positives = 131/252 (51%), Gaps = 23/252 (9%)
Query: 3 LKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQ 62
+ S++ Y + AG G + +V + T + +A+K I +S RE+ L+
Sbjct: 1 MPSSIYRYETIQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNVSK---VSLAREISCLR 57
Query: 63 ELKHVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHH 122
L H N+++L+D F + D +++V E +P + L G+ +
Sbjct: 58 NLHHRNILKLLDCFPSADLMSIVTEEVPYTW------------------YYTQILSGIAY 99
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLA--RLMASPQEILTSNVVTRWYRAPELLF 180
H I+HRD+KP N+L+ +KIADFG A + P + NV TRWYRAPELLF
Sbjct: 100 LHSKEIMHRDIKPENILVTSRNVVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPELLF 159
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
G+K Y VDIW++G I AEL+ P PG+ +++QI++ F LGTP + +WP + +
Sbjct: 160 GSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNEDNWPNWRTMPD 219
Query: 241 YNKIQIYPPPSR 252
NK+ P R
Sbjct: 220 ANKLLFEPKEPR 231
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 150 bits (378), Expect = 3e-36
Identities = 101/311 (32%), Positives = 166/311 (52%), Gaps = 25/311 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
Y E G G++ +V+ + TG +A+K++ + ++K+ RE++ +Q L H N
Sbjct: 83 YISEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN-------RELQIMQMLDHPN 135
Query: 69 VIELVDVFMAN-DN----LNLVLEFLPADLEIIIKD---TSIMFSPADIKSWILMTLRGV 120
+ L F + DN LNLVLEF+P + + + T+ + +K + R +
Sbjct: 136 AVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRAL 195
Query: 121 HHCHRNF-ILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ H +F + HRD+KP NLL+ P QLKI DFG A+++ + + S + +R+YRAPEL
Sbjct: 196 AYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNV-SYICSRYYRAPEL 254
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA YT+A+DIWS G + AEL+L P PG+ VDQ+ + LGTPT + ++ +
Sbjct: 255 IFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPN 314
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
++ + QI P P + ++R A++L+ +P R A++ F EL
Sbjct: 315 YTEFKFPQIKPHPWHKVFQKRL---PPEAVDLLCRFFQYSPNLRCTALEACIHPLFDELR 371
Query: 298 EPT--LPQDLP 306
+P LP P
Sbjct: 372 DPNTRLPNGRP 382
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 149 bits (376), Expect = 5e-36
Identities = 95/300 (31%), Positives = 158/300 (52%), Gaps = 14/300 (4%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKD--GLDMSALREVKFLQ 62
+++++Y K + G++ VY +K+ R A+K + S D G + +REV L+
Sbjct: 21 NSIENYEKVCRISSGSFGNVYRVRRKTDNRVFALKRMNPSMCYDTNGFSILYIREVMILK 80
Query: 63 ELKHVNVIELVDVFMAND--NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGV 120
++H N++E+ +V + + +V+E DL +I + A + L+G+
Sbjct: 81 HIRHRNIMEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVGKIGMKA-ARFLTCQMLKGL 139
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
H I+HRDLKP+N+LL DG L+IADFGLAR + S +T+ VVT WYR E+L
Sbjct: 140 KFLHGAGIVHRDLKPSNILLMRDGGLRIADFGLARAIESQ---MTNLVVTLWYRPIEILL 196
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWP--EVSSF 238
G++ Y ++D+WSVG + E++ P L G+ ++DQ++ FR LG PTDAD+ ++ F
Sbjct: 197 GSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTDADFEGLDLPHF 256
Query: 239 SNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPE 298
N + P F E A + ++ +P+KR A + L S + + E
Sbjct: 257 KNIRR----PSTFEASFEGDFECYGEEAASFVRNLLSFDPRKRCTASQGLCSGFVADAEE 312
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 149 bits (376), Expect = 5e-36
Identities = 99/300 (33%), Positives = 158/300 (52%), Gaps = 14/300 (4%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
V D ++ G G + VV+ T +G+ +A+K++ RE+K L +H
Sbjct: 40 VQDSQPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRH 99
Query: 67 VNVIELVDVFM-ANDN----LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVH 121
NV+ L+D+ AN + L ++ E + +DL II + +P +K ++ LRG+
Sbjct: 100 DNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQAL-TPDHVKVFVYQILRGLK 158
Query: 122 HCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLF 180
+ H ILHRD+KP NLL+ + LKI DFGLAR + +T VVT++YRAPELL
Sbjct: 159 YLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLM 218
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
GA+ YT AVDIWSVG IFAEL+ R ++Q+ + LGTP+ +
Sbjct: 219 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 278
Query: 241 YNKIQI-YPPPSREELRRRFIAATEN----ALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+ ++ P + L + IA+ ++ A++L+ ++ +P KR + LQ +Y +E
Sbjct: 279 NHVLRAGLRAPDTQRLYK--IASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 336
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 149 bits (376), Expect = 5e-36
Identities = 99/300 (33%), Positives = 158/300 (52%), Gaps = 14/300 (4%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
V D ++ G G + VV+ T +G+ +A+K++ RE+K L +H
Sbjct: 65 VQDSQPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRH 124
Query: 67 VNVIELVDVFM-ANDN----LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVH 121
NV+ L+D+ AN + L ++ E + +DL II + +P +K ++ LRG+
Sbjct: 125 DNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQAL-TPDHVKVFVYQILRGLK 183
Query: 122 HCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLF 180
+ H ILHRD+KP NLL+ + LKI DFGLAR + +T VVT++YRAPELL
Sbjct: 184 YLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLM 243
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
GA+ YT AVDIWSVG IFAEL+ R ++Q+ + LGTP+ +
Sbjct: 244 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 303
Query: 241 YNKIQI-YPPPSREELRRRFIAATEN----ALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+ ++ P + L + IA+ ++ A++L+ ++ +P KR + LQ +Y +E
Sbjct: 304 NHVLRAGLRAPDTQRLYK--IASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 361
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 149 bits (376), Expect = 5e-36
Identities = 99/300 (33%), Positives = 158/300 (52%), Gaps = 14/300 (4%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
V D ++ G G + VV+ T +G+ +A+K++ RE+K L +H
Sbjct: 237 VQDSQPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRH 296
Query: 67 VNVIELVDVFM-ANDN----LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVH 121
NV+ L+D+ AN + L ++ E + +DL II + +P +K ++ LRG+
Sbjct: 297 DNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQAL-TPDHVKVFVYQILRGLK 355
Query: 122 HCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLF 180
+ H ILHRD+KP NLL+ + LKI DFGLAR + +T VVT++YRAPELL
Sbjct: 356 YLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLM 415
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
GA+ YT AVDIWSVG IFAEL+ R ++Q+ + LGTP+ +
Sbjct: 416 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 475
Query: 241 YNKIQI-YPPPSREELRRRFIAATEN----ALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+ ++ P + L + IA+ ++ A++L+ ++ +P KR + LQ +Y +E
Sbjct: 476 NHVLRAGLRAPDTQRLYK--IASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 533
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 149 bits (375), Expect = 7e-36
Identities = 95/300 (31%), Positives = 151/300 (49%), Gaps = 6/300 (2%)
Query: 2 TLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFL 61
T+ + Y G G + +V T T + +A+K+I L RE+K L
Sbjct: 15 TVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLL 74
Query: 62 QELKHVNVIELVDVFMAN-DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGV 120
+ L+H N+I L D+F++ +++ V E DL +++ + ++ ++ LRG+
Sbjct: 75 KHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTRPL--EKQFVQYFLYQILRGL 132
Query: 121 HHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
+ H ++HRDLKP+N+L+ + LKI DFGLAR+ PQ +T V TR+YRAPE++
Sbjct: 133 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQ-DPQ--MTGYVSTRYYRAPEIML 189
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+ Y VDIWS G IFAE++ P PGKD V Q ++ LG+P + S +
Sbjct: 190 TWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENT 249
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPT 300
+ P RF +A++L+ M++ +PKKR A L Y +PT
Sbjct: 250 LKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPT 309
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 148 bits (374), Expect = 9e-36
Identities = 81/279 (29%), Positives = 144/279 (51%), Gaps = 1/279 (0%)
Query: 15 KAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVD 74
K GEG+Y V K+TG+ +A+K I + + ++ A+RE+KFL++ H N++ L++
Sbjct: 9 KVGEGSYGTVMKCKHKNTGQIVAIK-IFYERPEQSVNKIAMREIKFLKQFHHENLVNLIE 67
Query: 75 VFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHRDLK 134
VF ++LV EF+ + ++ ++ ++ LR + + H N I+HRD+K
Sbjct: 68 VFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIK 127
Query: 135 PNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSV 194
P N+L++ G K+ DFG AR +A+P +I T V TRWYRAPEL+ Y VDIW++
Sbjct: 128 PENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPVDIWAL 187
Query: 195 GVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPSREE 254
G + E+ PYLP D+D ++ +G + S + + + +
Sbjct: 188 GCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKN 247
Query: 255 LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
R+++ +++ + ++P R + L +YF
Sbjct: 248 ARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYF 286
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 148 bits (374), Expect = 9e-36
Identities = 97/308 (31%), Positives = 167/308 (53%), Gaps = 24/308 (7%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K T+ Y E+ G G++ VV+ TG ++A+K++ + ++K+ RE++ ++
Sbjct: 68 KQTIS-YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN-------RELQTMR 119
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPAD---IKSWIL 114
L H NV+ L F + LNLVLE++P + +IK + + +K +
Sbjct: 120 LLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTY 179
Query: 115 MTLRGVHHCHRNF-ILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRW 172
R + + HR + HRD+KP NLL+ P Q+K+ DFG A+++ + + S + +R+
Sbjct: 180 QIFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNI-SYICSRY 238
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YT+A+D+WS G + AEL+L P PG+ VDQ+ + LGTPT +
Sbjct: 239 YRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 298
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ +++ + QI P + +R A++L+S ++ +P R A+ L
Sbjct: 299 KCMNPNYTEFKFPQIKAHPWHKIFHKRM---PPEAVDLVSRLLQYSPNLRCAALDSLVHP 355
Query: 292 YFQELPEP 299
+F EL +P
Sbjct: 356 FFDELRDP 363
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 148 bits (373), Expect = 1e-35
Identities = 98/293 (33%), Positives = 158/293 (53%), Gaps = 14/293 (4%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRS-IAVKEIKTSQFKDGLDMSALREVKFLQE 63
+T +Y K + GEGT+ V L K GR+ A+K K S+ K+GL ++ +REV+ L+
Sbjct: 17 ATKMEYEKIRIIGEGTFGQVILARK---GRARYALK--KVSKEKEGLSVTTIREVQVLRA 71
Query: 64 LKHVNVIELVDVFMA-NDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHH 122
+ H +++ L++V + ++ +V + P DL I+ + S +IK +GV +
Sbjct: 72 MGHPSIVRLIEVVVEPGGDIYMVFPYFPYDLNRFIRSNKMTCS--EIKHIFYQIAQGVCY 129
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLK N+LL IADFG+AR + T +VT WYRAPE+L G+
Sbjct: 130 IHSKGIMHRDLKSANILLDQKLNASIADFGMARY-TTKTGAYTPGMVTLWYRAPEILLGS 188
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYN 242
YT AVDIWS+G I E+ L G ++ Q+ + A G+ + +P V +
Sbjct: 189 SSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGSINENSYPGVQDLPGFR 248
Query: 243 KIQIYPPPSR-EELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
++ P R E + R+ A +A+EL+S M+ ++P KR + + S+YF+
Sbjct: 249 NFRLPQSPRRIEGIIRKHDA---SAVELVSKMLCLDPSKRITVEQVVGSKYFE 298
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 148 bits (373), Expect = 1e-35
Identities = 97/308 (31%), Positives = 167/308 (53%), Gaps = 24/308 (7%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K T+ Y E+ G G++ VV+ TG ++A+K++ + ++K+ RE++ ++
Sbjct: 64 KQTIS-YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN-------RELQTMR 115
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPAD---IKSWIL 114
L H NV+ L F + LNLVLE++P + +IK + + +K +
Sbjct: 116 LLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTY 175
Query: 115 MTLRGVHHCHRNF-ILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRW 172
R + + HR + HRD+KP NLL+ P Q+K+ DFG A+++ + + S + +R+
Sbjct: 176 QIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNI-SYICSRY 234
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YT+A+D+WS G + AEL+L P PG+ VDQ+ + LGTPT +
Sbjct: 235 YRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 294
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ +++ + QI P + +R A++L+S ++ +P R A+ L
Sbjct: 295 KCMNPNYTEFKFPQIKAHPWHKIFHKRM---PPEAVDLVSRLLQYSPNLRSAALDTLVHP 351
Query: 292 YFQELPEP 299
+F EL +P
Sbjct: 352 FFDELRDP 359
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 147 bits (372), Expect = 1e-35
Identities = 82/210 (39%), Positives = 121/210 (57%), Gaps = 5/210 (2%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVF 76
G GTY VY T +A+K I+ ++ K+G+ +ALRE+ L++L H N+I LV +
Sbjct: 11 GSGTYGEVYEAIDTETKEKVALKRIRLNE-KEGMPGTALREISILKKLSHRNIISLVSII 69
Query: 77 MANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHRDLKPN 136
+ L +V F+ +L+ I M + +I + + GVH+ HR ++HRDLKP
Sbjct: 70 HTDALLTMVFPFIDYELKKYIG----MNTGKNIMELVNQLICGVHYLHRMNVVHRDLKPQ 125
Query: 137 NLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGV 196
N+L+ DG LKIADFGL+R + +S VVT WYR+PELL G+ Y VDIWS+G
Sbjct: 126 NILVTSDGVLKIADFGLSRSLEIRVPPYSSEVVTLWYRSPELLMGSTSYRFYVDIWSLGC 185
Query: 197 IFAELMLRIPYLPGKDDVDQINVTFRALGT 226
I E++ P PG+ +Q+ + R GT
Sbjct: 186 IIYEMITLEPLFPGESKENQLTLIRRKAGT 215
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 147 bits (372), Expect = 1e-35
Identities = 110/318 (34%), Positives = 165/318 (51%), Gaps = 27/318 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSA-LREVKFLQELKHVN 68
Y ++ G+G+Y VV +G +A+K+I F+ D + LRE+K L+ L+H +
Sbjct: 126 YQIQEVIGKGSYGVVASAIDTHSGEKVAIKKIN-DVFEHVSDATRILREIKLLRLLRHPD 184
Query: 69 VIELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
++E+ V + ++ +V E + +DL +IK + +P + ++ LRG+
Sbjct: 185 IVEIKHVMLPPSRREFRDIYVVFELMESDLHQVIKANDDL-TPEHYQFFLYQLLRGLKFI 243
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMAS--PQEIL-TSNVVTRWYRAPELL- 179
H + HRDLKP N+L D +LKI DFGLAR+ + P I T V TRWYRAPEL
Sbjct: 244 HTANVFHRDLKPKNILANSDCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCG 303
Query: 180 -FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSF 238
F +K YT A+DIWS+G IFAE++ P PGK+ V Q+++ LGTP PE +
Sbjct: 304 SFFSK-YTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPP----PEAIAR 358
Query: 239 SNYNKIQIYPPPSREE----LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
K + Y R + +F AL L+ ++ +PK R A + L YF
Sbjct: 359 IRNEKARRYLGNMRRKPPVPFTHKFPHVDPLALRLLHRLLAFDPKDRPSAEEALADPYFY 418
Query: 295 ELP----EPTLPQDLPKL 308
L EP+ Q +PKL
Sbjct: 419 GLANVDREPS-TQPIPKL 435
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 147 bits (372), Expect = 1e-35
Identities = 101/316 (31%), Positives = 168/316 (52%), Gaps = 28/316 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
YT K G G++ VV+ TG +A+K++ + +FK+ RE++ +++L+H N
Sbjct: 548 YTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKN-------RELQIMRKLEHCN 600
Query: 69 VIELVDVFMANDN------LNLVLEFLPADLEIIIKD---TSIMFSPADIKSWILMTLRG 119
+++L+ F ++ LNLVLE++P + + + T I+ ++ R
Sbjct: 601 IVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRS 660
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ + H I HRD+KP NLLL P+ LK+ DFG A+ + + + S + +R+YRAPEL
Sbjct: 661 LAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNV-SYICSRYYRAPEL 719
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA +YT+ +D+WS G + AEL+L P PG VDQ+ + LGTPT E++ +
Sbjct: 720 IFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPN 779
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL- 296
++ + QI P ++ R I A+ L+S ++ P R +K +F EL
Sbjct: 780 YTEFKFPQIKSHPWQKVFR---IRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELR 836
Query: 297 --PEPTLP--QDLPKL 308
TLP +D+P L
Sbjct: 837 MEGNHTLPNGRDMPPL 852
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 147 bits (371), Expect = 2e-35
Identities = 100/317 (31%), Positives = 169/317 (52%), Gaps = 26/317 (8%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K T+ Y E+ G G++ +V+ TG S+A+K++ + ++K+ RE++ ++
Sbjct: 67 KQTIS-YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN-------RELQLMR 118
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPADI---KSWIL 114
+ H NV+ L F + LNLV+E++P L ++K + I K +
Sbjct: 119 LMDHPNVVSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTY 178
Query: 115 MTLRGVHHCHRN-FILHRDLKPNNLLLAP-DGQLKIADFGLARLMASPQEILTSNVVTRW 172
RG+ + H + HRD+KP NLL+ P Q K+ DFG A+++ + + S + +R+
Sbjct: 179 QIFRGLAYIHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLVKGEANI-SYICSRY 237
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YTS++DIWS G + AEL+L P PG++ VDQ+ + LGTPT +
Sbjct: 238 YRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEI 297
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ +++++ QI P + +R A++L S ++ +P R A++
Sbjct: 298 RCMNPNYTDFRFPQIKAHPWHKVFHKRM---PPEAIDLASRLLQYSPSLRCTALEACAHP 354
Query: 292 YFQELPEPT--LPQDLP 306
+F EL EP LP P
Sbjct: 355 FFNELREPNARLPNGRP 371
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 147 bits (371), Expect = 2e-35
Identities = 102/311 (32%), Positives = 163/311 (51%), Gaps = 25/311 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
Y E G G++ +V+ + TG +A+K++ + ++K+ RE++ +Q L H N
Sbjct: 82 YIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN-------RELQIMQMLDHPN 134
Query: 69 VIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPAD---IKSWILMTLRGV 120
V+ L F + LNLVLEF+P + + S M +K + RG+
Sbjct: 135 VVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGL 194
Query: 121 HHCHRNF-ILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ H + HRD+KP NLL+ P QLKI DFG A+++ + + S + +R+YRAPEL
Sbjct: 195 AYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNI-SYICSRYYRAPEL 253
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA YT+A+DIWS G + AEL+L P PG+ VDQ+ + LGTPT + ++ +
Sbjct: 254 IFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPN 313
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
++ + QI P P + ++R A++L+ +P R AV+ +F EL
Sbjct: 314 YTEFKFPQIKPHPWHKVFQKRL---PPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELR 370
Query: 298 EPT--LPQDLP 306
+P LP P
Sbjct: 371 DPNARLPNGRP 381
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 147 bits (371), Expect = 2e-35
Identities = 99/317 (31%), Positives = 171/317 (53%), Gaps = 26/317 (8%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K T+ Y E+ G G++ +V+ TG S+A+K++ + ++K+ RE++ ++
Sbjct: 65 KQTIS-YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN-------RELQLMR 116
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPADI---KSWIL 114
+ H NVI L F + + LNLV+E++P L +++ + I K +
Sbjct: 117 PMDHPNVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTY 176
Query: 115 MTLRGVHHCHR-NFILHRDLKPNNLLLAP-DGQLKIADFGLARLMASPQEILTSNVVTRW 172
RG+ + H + HRD+KP NLL+ P Q+K+ DFG A+++ + + S + +R+
Sbjct: 177 QIFRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNI-SYICSRY 235
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YT+++DIWS G + AEL+L P PG++ VDQ+ + LGTPT +
Sbjct: 236 YRAPELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEI 295
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ +++++ QI P + +R A++L S ++ +P R A++
Sbjct: 296 RCMNPNYTDFRFPQIKAHPWHKVFHKRM---PPEAIDLASRLLQYSPSLRCTALEACAHP 352
Query: 292 YFQELPEPT--LPQDLP 306
+F EL EP LP P
Sbjct: 353 FFNELREPNARLPNGRP 369
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 147 bits (370), Expect = 2e-35
Identities = 96/267 (35%), Positives = 131/267 (48%), Gaps = 11/267 (4%)
Query: 2 TLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFL 61
T+ + Y G G Y V TG +AVK++ RE++ L
Sbjct: 16 TIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 62 QELKHVNVIELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILM 115
+ +KH NVI L+DVF +L LV + ADL I+K + + ++ I
Sbjct: 76 KHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKL--TDDHVQFLIYQ 133
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRA 175
LRG+ + H I+HRDLKP+NL + D +LKI DFGLAR + +T V TRWYRA
Sbjct: 134 ILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR---HTDDEMTGYVATRWYRA 190
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEV 235
PE++ HY VDIWSVG I AEL+ PG D +DQ+ + R +GTP ++
Sbjct: 191 PEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
Query: 236 SSFSNYNKIQIYPPPSREELRRRFIAA 262
SS S N IQ + FI A
Sbjct: 251 SSESARNYIQSLTQMPKMNFANVFIGA 277
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 147 bits (370), Expect = 2e-35
Identities = 106/302 (35%), Positives = 158/302 (52%), Gaps = 22/302 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSA-LREVKFLQELKHVN 68
Y E+ G+G+Y VV TG +A+K+I F+ D + LRE+K L+ L+H +
Sbjct: 25 YRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDI-FEHVSDATRILREIKLLRLLRHPD 83
Query: 69 VIELVDVFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
++E+ + + ++ +V E + +DL +IK + +P + ++ LRG+ +
Sbjct: 84 IVEIKHILLPPSRREFRDIYVVFELMESDLHQVIKANDDL-TPEHYQFFLYQLLRGLKYI 142
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMAS--PQEIL-TSNVVTRWYRAPELL- 179
H + HRDLKP N+L D +LKI DFGLAR+ + P I T V TRWYRAPEL
Sbjct: 143 HTANVFHRDLKPKNILANADCKLKICDFGLARVAFNDTPTAIFWTDYVATRWYRAPELCG 202
Query: 180 -FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSF 238
F +K YT A+DIWS+G IFAEL+ P PGK+ V Q+++ LGTP+ E
Sbjct: 203 SFFSK-YTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPS----AEAIGR 257
Query: 239 SNYNKIQIYPPPSREE----LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
K + Y R++ +F AL L+ M+ PK R A + L YF+
Sbjct: 258 VRNEKARRYLSSMRKKKPIPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEALADVYFK 317
Query: 295 EL 296
L
Sbjct: 318 GL 319
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 146 bits (369), Expect = 3e-35
Identities = 94/290 (32%), Positives = 151/290 (51%), Gaps = 16/290 (5%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKH 66
++ Y K+ GEG + VY + S G A+K++ + + G +A+RE+K + + +
Sbjct: 1 MEKYENIKQVGEGAFGQVYKSRRTSDGAVFAIKKMPVDR-ETGFPFTAIREIKLCKSVIN 59
Query: 67 VNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRN 126
++I L ++ + +VLE++P DL ++ + S I+S + V H
Sbjct: 60 KHIIGLDEIVFEEGFIFVVLEYMPYDLTGLLA-SGAKLSTDQIRSITSQLIEAVSSMHGM 118
Query: 127 FILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYT 186
++HRD+KP+N+LL G LK+ DFGL R ++ ++T+ V T WYRAPELL G Y+
Sbjct: 119 GLVHRDIKPSNILLDCHGMLKLTDFGLTREISG---MMTNRVCTLWYRAPELLLGETSYS 175
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDA-DWPEVSSFSNYNKIQ 245
VD WSVG I E+ L P G D+V QI + F LG P D W ++ Y+K +
Sbjct: 176 LKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQDKYKWSDLLDVDIYSKSR 235
Query: 246 IYPPPSREEL--RRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
S EE+ R E L+++SG + + +KR + S+YF
Sbjct: 236 -----STEEIIAERYGHLFDEEELKVLSGFLCLTSRKR---LSVANSRYF 277
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 146 bits (368), Expect = 4e-35
Identities = 96/304 (31%), Positives = 158/304 (51%), Gaps = 23/304 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
YT K G G++ VVY +G +A+K++ + +FK+ RE++ +++L H N
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN-------RELQIMRKLDHCN 108
Query: 69 VIELVDVFMANDN------LNLVLEFLPADLEIIIKDTSIMFSPADI---KSWILMTLRG 119
++ L F ++ LNLVL+++P + + + S + K ++ R
Sbjct: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ + H I HRD+KP NLLL PD LK+ DFG A+ + + + S + +R+YRAPEL
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNV-SYICSRYYRAPEL 227
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA YTS++D+WS G + AEL+L P PG VDQ+ + LGTPT E++ +
Sbjct: 228 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 287
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
++ + QI P + R R A+ L S ++ P R ++ +F EL
Sbjct: 288 YTEFKFPQIKAHPWTKVFRPR---TPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELR 344
Query: 298 EPTL 301
+P +
Sbjct: 345 DPNV 348
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 145 bits (367), Expect = 6e-35
Identities = 99/307 (32%), Positives = 157/307 (50%), Gaps = 21/307 (6%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
+T + G G++ VY + IA+K+IK D RE+ + E+ H N+
Sbjct: 37 FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVD------DRFKSRELTIMHEMDHPNI 90
Query: 70 IELVDVF-MANDN-LNLVLEFLPADLEIIIKD---TSIMFSPADIKSWILMTLRGVHHCH 124
I L+ + M +N LN V+EF+P DL + + IK ++ LRG+ H
Sbjct: 91 IRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIKLYMFQLLRGIGFLH 150
Query: 125 RNFILHRDLKPNNLLL-APDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
+ I+HRD+KP NLL+ +G LKI DFG A+ + + +T + +R+YRAPEL+FG+K
Sbjct: 151 LHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITY-ICSRYYRAPELIFGSK 209
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
+Y +++D WSVG + EL+ P VD + + +A GTP+ D + NY
Sbjct: 210 NYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAK----WNYEY 265
Query: 244 IQIYPPPSREELRRRFIA--ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP-- 299
+ I ++FI + + LEL++ +M M+PK R + L YF +L +P
Sbjct: 266 VHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRIKPYEALTLPYFDDLRDPHY 325
Query: 300 TLPQDLP 306
LP P
Sbjct: 326 KLPSGAP 332
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 145 bits (366), Expect = 7e-35
Identities = 92/299 (30%), Positives = 144/299 (47%), Gaps = 17/299 (5%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y ++ G G + VV + +A+K+I ALRE++ +EL H N+
Sbjct: 44 YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSHENI 103
Query: 70 IELVDVFM----ANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
I DV M + ++ +V++ + DL ++K + + + + L+G+ + H
Sbjct: 104 INSTDVLMRESGSGQDIYIVMDLMETDLLSVLKSNQTL-NEKHFQYFFYQILKGLKYLHS 162
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI------------LTSNVVTRWY 173
I+HRDLKP NLLL D LKIADFG++R S + L+ V T WY
Sbjct: 163 AGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWY 222
Query: 174 RAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWP 233
RAPE+L Y + VDIWS G I AE++L P G D QI + LGTP +
Sbjct: 223 RAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIR 282
Query: 234 EVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
+ S S + I + P + F A+ A ++S M+ ++P KR+ A + L+ +
Sbjct: 283 RIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLLEEPF 341
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 144 bits (363), Expect = 2e-34
Identities = 99/317 (31%), Positives = 169/317 (53%), Gaps = 26/317 (8%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K T+ Y E+ G G++ +V+ TG ++A+K++ + ++K+ RE++ ++
Sbjct: 35 KQTIS-YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-------RELQLMR 86
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPAD---IKSWIL 114
+ H NV+ L F + + LNLV+E++P L ++K S +K ++
Sbjct: 87 VMDHPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMY 146
Query: 115 MTLRGVHHCHRNF-ILHRDLKPNNLLLAP-DGQLKIADFGLARLMASPQEILTSNVVTRW 172
RG+ + H + HRDLKP NLL+ P Q+KI DFG A+ + + + S + +R+
Sbjct: 147 QIFRGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANI-SYICSRF 205
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YT+++DIWS G + AEL+L P PG++ VDQ+ + LGTPT +
Sbjct: 206 YRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEI 265
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ ++++ QI P + +R A++ S ++ +P R A++
Sbjct: 266 RCMNPHYTDFRFPQIKAHPWHKIFHKRM---PPEAIDFASRLLQYSPSLRCTALEACAHP 322
Query: 292 YFQELPEPT--LPQDLP 306
+F EL EP LP P
Sbjct: 323 FFDELREPNARLPNGRP 339
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 144 bits (362), Expect = 2e-34
Identities = 101/299 (33%), Positives = 151/299 (49%), Gaps = 14/299 (4%)
Query: 14 KKAGEGTYAVVYLG--TKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK-HVNVI 70
K+ G G Y +V + + ++A+K++ K L +LRE+K L+ + H N+
Sbjct: 27 KEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 86
Query: 71 ELVD---VFMANDNLN---LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
L D VF + ++N L E + D+ IIK + + A +S+ L G+ + H
Sbjct: 87 CLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPL-TDAHYQSFTYQILCGLKYIH 145
Query: 125 RNFILHRDLKPNNLLLAPDGQLKIADFGLAR-LMASPQE---ILTSNVVTRWYRAPELLF 180
+LHRDLKP NLL+ D QLKI DFGLAR +P E LT V TRWYRAPE++
Sbjct: 146 SADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIML 205
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+ YT A+D+WS G I AE + P GKD V+Q+N + LGTP D + S +
Sbjct: 206 SYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNV 265
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEP 299
+ I + + A AL+L+ M+ +P+KR + L+ Y +P
Sbjct: 266 QDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDP 324
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 144 bits (362), Expect = 2e-34
Identities = 92/299 (30%), Positives = 154/299 (50%), Gaps = 23/299 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
YT K G G++ VVY T +A+K++ + +FK+ RE++ +++L H N
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN-------RELQIMRKLDHCN 171
Query: 69 VIELVDVFMANDN------LNLVLEFLPADLEIIIKD---TSIMFSPADIKSWILMTLRG 119
++ L F ++ LNLVLE++P + + + + +K ++ R
Sbjct: 172 IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRS 231
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ + H + HRD+KP NLL+ PD LK+ DFG A+ + + + S + +R+YRAPEL
Sbjct: 232 LAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNV-SYICSRYYRAPEL 290
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA YTS++D+WS G + AEL+L P PG VDQ+ + LGTPT E++ +
Sbjct: 291 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 350
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
++ + QI P + + R A+ L S ++ P R ++ +F EL
Sbjct: 351 YTEFKFPQIKAHPWTKVFKSR---TPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 144 bits (362), Expect = 2e-34
Identities = 92/299 (30%), Positives = 154/299 (50%), Gaps = 23/299 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
YT K G G++ VVY T +A+K++ + +FK+ RE++ +++L H N
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN-------RELQIMRKLDHCN 171
Query: 69 VIELVDVFMANDN------LNLVLEFLPADLEIIIKD---TSIMFSPADIKSWILMTLRG 119
++ L F ++ LNLVLE++P + + + + +K ++ R
Sbjct: 172 IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRS 231
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ + H + HRD+KP NLL+ PD LK+ DFG A+ + + + S + +R+YRAPEL
Sbjct: 232 LAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNV-SYICSRYYRAPEL 290
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA YTS++D+WS G + AEL+L P PG VDQ+ + LGTPT E++ +
Sbjct: 291 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 350
Query: 238 FSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
++ + QI P + + R A+ L S ++ P R ++ +F EL
Sbjct: 351 YTEFKFPQIKAHPWTKVFKSR---TPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 142 bits (359), Expect = 5e-34
Identities = 97/295 (32%), Positives = 155/295 (51%), Gaps = 10/295 (3%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSAL-REVKFLQELKHV 67
D ++ G G + VV+ T G+ +A+K++ + F++ + + RE+K L KH
Sbjct: 125 DIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMP-NVFQNLVSCKRVFRELKMLCFFKHD 183
Query: 68 NVIELVDVFMAN-----DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHH 122
NV+ +D+ + + +V E + +DL II + S +K ++ LRG+ +
Sbjct: 184 NVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSD-HVKVFLYQILRGLKY 242
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI-LTSNVVTRWYRAPELLFG 181
H ILHRD+KP NLL+ + LKI DFGLAR+ + +T VVT++YRAPE+L G
Sbjct: 243 LHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMG 302
Query: 182 AKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPT-DADWPEVSSFSN 240
++HY++A+DIWSVG IFAEL+ R + + Q+++ LGTP+ +A
Sbjct: 303 SRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKA 362
Query: 241 YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+ + PS L AT A+ L+ M++ +P KR A L Y E
Sbjct: 363 HILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 417
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 142 bits (359), Expect = 5e-34
Identities = 90/244 (36%), Positives = 124/244 (49%), Gaps = 11/244 (4%)
Query: 2 TLKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFL 61
T+ + Y G G Y V TG +AVK++ RE++ L
Sbjct: 16 TIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 62 QELKHVNVIELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILM 115
+ +KH NVI L+DVF +L LV + ADL I+K + + ++ I
Sbjct: 76 KHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKL--TDDHVQFLIYQ 133
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRA 175
LRG+ + H I+HRDLKP+NL + D +LKI DFGLAR + +T V TRWYRA
Sbjct: 134 ILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR---HTDDEMTGYVATRWYRA 190
Query: 176 PELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEV 235
PE++ HY VDIWSVG I AEL+ PG D +DQ+ + R +GTP ++
Sbjct: 191 PEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
Query: 236 SSFS 239
SS S
Sbjct: 251 SSES 254
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 142 bits (358), Expect = 6e-34
Identities = 100/301 (33%), Positives = 157/301 (51%), Gaps = 20/301 (6%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLD-MSALREVKFLQELKHVN 68
Y ++ G+G+Y VV TG +A+K++ T+ F+ D + LRE+K L+ L+H +
Sbjct: 16 YQIQEVVGKGSYGVVASAECPHTGGKVAIKKM-TNVFEHVSDAIRILREIKLLRLLRHPD 74
Query: 69 VIELVDVFMAN-----DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
++E+ + + ++ +V E + +DL ++K + +P + ++ LRG+
Sbjct: 75 IVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKVNDDL-TPQHHQFFLYQLLRGLKFM 133
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMA--SPQEIL-TSNVVTRWYRAPELLF 180
H + HRDLKP N+L D ++KI D GLAR+ SP + T V TRWYRAPEL
Sbjct: 134 HSAHVFHRDLKPKNILANADCKIKICDLGLARVSFTDSPSAVFWTDYVATRWYRAPELCG 193
Query: 181 GA-KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
+YT A+D+WSVG IFAE++ P PGK+ V Q+ + LGTP+ P S
Sbjct: 194 SFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPS----PITLSRI 249
Query: 240 NYNKIQIYPPPSREE----LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
K + Y R + +F AL+L+ ++ +PK R A + L YFQ
Sbjct: 250 RNEKARKYLGNMRRKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALADPYFQG 309
Query: 296 L 296
L
Sbjct: 310 L 310
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 141 bits (355), Expect = 1e-33
Identities = 96/310 (30%), Positives = 166/310 (52%), Gaps = 24/310 (7%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K T+ Y ++ G G++ VV+ TG +A+K++ + ++K+ RE++ ++
Sbjct: 133 KQTIS-YMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKN-------RELQIMR 184
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPADI---KSWIL 114
H NV+ L F + + LNLVLE++P + K + M I + +
Sbjct: 185 LQDHPNVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTY 244
Query: 115 MTLRGVHHCHRNF-ILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRW 172
R +++ HR + HRD+KP NLL+ P QLKI DFG A+++ P E S + +R+
Sbjct: 245 QICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLV-PGEPNISYICSRY 303
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YT+A+D+WS G + AEL+L P PG+ +DQ+ + LGTPT +
Sbjct: 304 YRAPELIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTREEI 363
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ +++ + QI P + +R A++L+S ++ +P R A++
Sbjct: 364 RCMNPNYTEFKFPQIKAHPWHKIFHKRM---PPEAVDLVSRLLQYSPNLRCTALEACAHP 420
Query: 292 YFQELPEPTL 301
+F +L +P +
Sbjct: 421 FFDDLRDPNV 430
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 140 bits (353), Expect = 2e-33
Identities = 88/298 (29%), Positives = 150/298 (49%), Gaps = 15/298 (5%)
Query: 6 TVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK 65
T+ D+ + G+G Y VY G+ A+K+I S +G+ S LRE+ ++ L
Sbjct: 34 TMKDFQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLA 93
Query: 66 ---HVNVIELVDVFMAND------NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMT 116
H N+I L VF D +N+++E DL +++ K
Sbjct: 94 RKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQI 153
Query: 117 LRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAP 176
+R + H + I+HRDLKP N+LL D +K+ADFGL++ ++ T+ VVT WYR+P
Sbjct: 154 VRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTAF-TTLVVTLWYRSP 212
Query: 177 ELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS 236
E+L + +Y S VD+W++G I +E+ R P G+++ +Q+ F+ +GTP DWP S
Sbjct: 213 EVLLQS-YYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSES 271
Query: 237 SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
+ + Y P + ++L + ++ A+E + + + KR A L + +
Sbjct: 272 VIAR-DSFPQYRPTNLKDLSPQM---SKQAIEFVQQCLRYDHSKRLSARGALSHPFLK 325
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 140 bits (352), Expect = 3e-33
Identities = 97/314 (30%), Positives = 160/314 (50%), Gaps = 30/314 (9%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELKHVN 68
YT K G G++ VVY +G +A+K++ + +FK+ RE++ +++L H N
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN-------RELQIMRKLDHCN 108
Query: 69 VIELVDVFMANDN------LNLVLEFLPADLEIIIKDTSIMFSPADI---KSWILMTLRG 119
++ L F ++ LNLVL+++P + + + S + K ++ R
Sbjct: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
Query: 120 VHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVVTRWYRAPEL 178
+ + H I HRD+KP NLLL PD LK+ DFG A+ + + + S + +R+YRAPEL
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNV-SYICSRYYRAPEL 227
Query: 179 LFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-S 237
+FGA YTS++D+WS G + AEL+L P PG VDQ+ + LGTPT E++ +
Sbjct: 228 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 287
Query: 238 FSNYNKIQIYPPPSREELR---------RRFIAAT-ENALELISGMMIMNPKKRWDAVKC 287
++ + QI P ++ R F T A+ L S ++ P R ++
Sbjct: 288 YTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEA 347
Query: 288 LQSQYFQELPEPTL 301
+F EL +P +
Sbjct: 348 CAHSFFDELRDPNV 361
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 139 bits (350), Expect = 5e-33
Identities = 99/323 (30%), Positives = 160/323 (48%), Gaps = 44/323 (13%)
Query: 4 KSTVDDYTKEKKA---------GEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMS 53
K D T EKK G G++ VV T IAVK + + ++K+
Sbjct: 10 KVVTDGTTGEKKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKN----- 64
Query: 54 ALREVKFLQELKHVNVIELVDVFMAND------NLNLVLEFLPADLEIIIKDTSIM---- 103
RE++ ++ + H N+I+L+ F ++ +L L+LE++P E + D
Sbjct: 65 --RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMP---ETVFDDMRWYTRRR 119
Query: 104 --FSPADIKSWILMTLRGVHHCHRNFILHRDLKPNNLLLA-PDGQLKIADFGLARLMASP 160
IK + R + + H + HRD+KP NLL+ G LK+ DFG A+++ P
Sbjct: 120 KSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLV-P 178
Query: 161 QEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVT 220
E S + +R+YRAPEL+FGA HYT+ +D+WS + AEL + P PG V+Q+
Sbjct: 179 SEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEI 238
Query: 221 FRALGTPTDADWPEVS----SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIM 276
R LGTP+ + E+S ++ N++ + P + T+NA++L+ M+
Sbjct: 239 IRVLGTPS---YHEISVMNPNYVNHSLPNVRPHTLESVMPHN---CTKNAMDLLHKMLTY 292
Query: 277 NPKKRWDAVKCLQSQYFQELPEP 299
P KR A++ L +F EL +P
Sbjct: 293 VPSKRISAIEVLTHPFFDELRDP 315
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 138 bits (347), Expect = 1e-32
Identities = 95/308 (30%), Positives = 161/308 (51%), Gaps = 23/308 (7%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K Y E G G++ VV+ T +A+K++ + ++K+ RE++ ++
Sbjct: 96 KDKTISYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKN-------RELQIMR 148
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPAD---IKSWIL 114
L H NV+EL F + LNLVLE++P + + + M I+ +
Sbjct: 149 MLDHPNVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTY 208
Query: 115 MTLRGVHHCHRNF-ILHRDLKPNNLLLAP-DGQLKIADFGLARLMASPQEILTSNVVTRW 172
R +++ H+ + HRD+KP NLL+ ++KI DFG A+++ P E S + +R+
Sbjct: 209 QICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLI-PGEPNISYICSRY 267
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YTSA+D+WSVG + AEL L P PG+ VDQ+ + LGTP +
Sbjct: 268 YRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEI 327
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ ++++ QI P + RR+ + A++L S ++ +P R A++
Sbjct: 328 KNMNPRYNDFKFPQIKAQPWHKIFRRQ---VSPEAMDLASRLLQYSPNLRCTALEACAHP 384
Query: 292 YFQELPEP 299
+F +L +P
Sbjct: 385 FFDDLRDP 392
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 138 bits (347), Expect = 1e-32
Identities = 91/287 (31%), Positives = 144/287 (49%), Gaps = 10/287 (3%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVF 76
G+G+Y VV TG +A+K+I + LREVK L+ L+H +++E+ +
Sbjct: 20 GKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRHPDIVEIKSIM 79
Query: 77 MAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHR 131
+ ++ +V E + +DL +IK + + + ++ LR + + H + HR
Sbjct: 80 LPPSKREFKDIYVVFELMESDLHQVIKANDDL-TREHHQFFLYQMLRALKYMHTANVYHR 138
Query: 132 DLKPNNLLLAPDGQLKIADFGLARLMAS--PQEIL-TSNVVTRWYRAPELLFG-AKHYTS 187
DLKP N+L + +LK+ DFGLAR+ + P + T V TRWYRAPEL YT
Sbjct: 139 DLKPKNILANANCKLKVCDFGLARVSFNDTPTTVFWTDYVATRWYRAPELCGSFCSKYTP 198
Query: 188 AVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIY 247
A+DIWS+G IFAE++ P PGK V Q+++ LGTP V + +
Sbjct: 199 AIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETIAGVRNEKARKYLNEM 258
Query: 248 PPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
+ ++F A AL L+ ++ +PK R A + L YF+
Sbjct: 259 RKKNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEALADPYFK 305
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 137 bits (345), Expect = 2e-32
Identities = 98/296 (33%), Positives = 152/296 (51%), Gaps = 24/296 (8%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKT--SQFKDGLDMSALREVKFLQELKHVNVIELVD 74
G+G+Y VV TG +A+K+I D L + LREVK L+ L+H +++E+
Sbjct: 20 GKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRI--LREVKLLRLLRHPDIVEIKS 77
Query: 75 VFMAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFIL 129
+ + ++ +V E + +DL +IK + + + ++ LR + H +
Sbjct: 78 IMLPPSKREFKDIYVVFELMESDLHQVIKANDDL-TREHHQFFLYQMLRALKFMHTANVY 136
Query: 130 HRDLKPNNLLLAPDGQLKIADFGLARLMAS--PQEIL-TSNVVTRWYRAPELL--FGAKH 184
HRDLKP N+L + +LK+ DFGLAR+ + P + T V TRWYRAPEL F +K
Sbjct: 137 HRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVFWTDYVATRWYRAPELCGSFFSK- 195
Query: 185 YTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
YT A+D+WS+G IFAE++ P PGK V Q+ + LGTP E S +K
Sbjct: 196 YTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKS----ETISGVRNDKA 251
Query: 245 QIYPPPSREE----LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
+ Y R++ ++F A AL L+ ++ +PK R + L YF+ L
Sbjct: 252 RKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADPYFKGL 307
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 137 bits (344), Expect = 3e-32
Identities = 100/302 (33%), Positives = 151/302 (49%), Gaps = 22/302 (7%)
Query: 17 GEGTYAVVYLGTKKSTGRS----IAVKEIKTSQFKDGLDMSALREVKFLQELK-HVNVIE 71
G+G Y V + K GRS IAVK+I K+ L A+RE+KF+ K H N++
Sbjct: 45 GKGAYGTVC--SVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVN 102
Query: 72 LVDVFMAN----DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNF 127
L+D+ + D L E + DL +I +S+ S IK ++ L G+ + H
Sbjct: 103 LIDLEIVTSSPYDGLYCYQELIDYDLAKVIH-SSVQLSEFHIKYFLYQILCGLKYIHSAD 161
Query: 128 ILHRDLKPNNLLLAPDGQLKIADFGLARLM--------ASPQEILTSNVVTRWYRAPELL 179
++HRDLKP N+L +G LKI DFGLAR + ++ Q +T+ V TRWYRAPELL
Sbjct: 162 VIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELL 221
Query: 180 FGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
+ Y+ +VDIW+VG I AE R P G+D + QI + LGTP + +
Sbjct: 222 LSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIK 281
Query: 240 NYN--KIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
+N K P + F A+ A+ LI ++ + R + + + + E+
Sbjct: 282 AWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVR 341
Query: 298 EP 299
+P
Sbjct: 342 KP 343
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 137 bits (344), Expect = 3e-32
Identities = 86/287 (29%), Positives = 145/287 (49%), Gaps = 15/287 (5%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK---HVNVIELV 73
G+G Y VY G+ A+K+I S +G+ S LRE+ ++ L H N+I L
Sbjct: 109 GKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISLK 168
Query: 74 DVFMAND------NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNF 127
VF D +N+++E DL +++ K +R + H +
Sbjct: 169 SVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHS 228
Query: 128 ILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTS 187
I+HRDLKP N+LL D +K+ADFGL++ ++ T+ VVT WYR+PE+L + +Y S
Sbjct: 229 IIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTAF-TTLVVTLWYRSPEVLLQS-YYNS 286
Query: 188 AVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIY 247
VD+W++G I +E+ R P G+++ +Q+ F+ +GTP DWP S + + Y
Sbjct: 287 TVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSESVIAR-DSFPQY 345
Query: 248 PPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
P + ++L + ++ A+E + + + KR A L + +
Sbjct: 346 RPTNLKDLSPQM---SKQAIEFVQQCLRYDHSKRLSARGALSHPFLK 389
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 137 bits (344), Expect = 3e-32
Identities = 94/308 (30%), Positives = 163/308 (52%), Gaps = 26/308 (8%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQ 62
K T+ Y E+ G+G++ +V+ TG ++A+K++ + ++K+ RE++ ++
Sbjct: 69 KQTIS-YMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKN-------RELQTMR 120
Query: 63 ELKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIKDTSIMFSPADI---KSWIL 114
L H NV+ L F + LNLVLE++P + + K S I K +
Sbjct: 121 LLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTY 180
Query: 115 MTLRGVHHCHRNF-ILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRW 172
R + + H + HRD+KP NLL+ P Q+K+ DFG A+++ + + S + +R+
Sbjct: 181 QICRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNI-SYICSRY 239
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADW 232
YRAPEL+FGA YT+ +DIWS G + AEL+L P PG+ VDQ+ + LGTPT +
Sbjct: 240 YRAPELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 299
Query: 233 PEVS-SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQ 291
++ +++ + QI P + +R A++L+S ++ +P R + +
Sbjct: 300 KCMNPNYTEFKFPQIKAHPWHKIFHKR---TPPEAVDLVSRLLQYSPNLR--STAAIVHP 354
Query: 292 YFQELPEP 299
+F EL +P
Sbjct: 355 FFDELRDP 362
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 137 bits (344), Expect = 3e-32
Identities = 98/294 (33%), Positives = 156/294 (52%), Gaps = 20/294 (6%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVF 76
G+G+Y VV TG +A+K+I LRE+K L+ L+H +++E+ +
Sbjct: 20 GKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHPDIVEIKHIM 79
Query: 77 MAND-----NLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHR 131
+ ++ +V E + +DL +IK + + + ++ LR + + H + HR
Sbjct: 80 LPPSRREFKDIYVVFELMESDLHQVIKANDDL-TREHYQFFLYQLLRALKYIHTANVYHR 138
Query: 132 DLKPNNLLLAPDGQLKIADFGLARLMAS--PQEIL-TSNVVTRWYRAPELL--FGAKHYT 186
DLKP N+L + +LKI DFGLAR+ + P I T V TRWYRAPEL F +K YT
Sbjct: 139 DLKPKNILANANCKLKICDFGLARVAFNDTPTTIFWTDYVATRWYRAPELCGSFYSK-YT 197
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQI 246
A+DIWS+G IFAE+++ P PGK+ V Q+++ LGTP+ +S N K +
Sbjct: 198 PAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPS---LDTISRVRN-EKARR 253
Query: 247 YPPPSREE----LRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQEL 296
Y R++ ++F A +L+L+ ++ +PK R A + L YF+ L
Sbjct: 254 YLTSMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEALADPYFKGL 307
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 134 bits (338), Expect = 1e-31
Identities = 96/291 (32%), Positives = 143/291 (48%), Gaps = 14/291 (4%)
Query: 15 KAGEGTYAVVYLGTKKSTGRS--IAVKEIKTSQFKDGLDMSALREVKFLQELK-HVNVIE 71
K G G+++++ T + +A+++I + LRE+K L+ L+ H N++
Sbjct: 28 KIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVW 87
Query: 72 LVD---VFMANDNLN---LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
L D VF N LN L E + DL II+ + A +S+I L + + H
Sbjct: 88 LFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRL-EDAHFQSFIYQILCALKYIHS 146
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEI----LTSNVVTRWYRAPELLFG 181
+LH DLKP NLL+ D QLKI +FGL+ + ++ + + + WY+APE+L
Sbjct: 147 ANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLN 206
Query: 182 AKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNY 241
+ T AVDIWS G I AEL+ R P GKD VD +N + LGTP + E++S Y
Sbjct: 207 YQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVY 266
Query: 242 NKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQY 292
N I + A ALEL+ M+ +PKKR L+ Y
Sbjct: 267 NYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPY 317
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 134 bits (337), Expect = 2e-31
Identities = 104/308 (33%), Positives = 154/308 (49%), Gaps = 24/308 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + K G G +V G ++AVK++ A RE+ L+ + H N+
Sbjct: 26 YQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I M + S++L L G+ H
Sbjct: 86 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TACTNFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-SFSNY 241
Y VDIWSVG I AE++L PG+D +DQ N LGTP+ ++ + NY
Sbjct: 200 MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNY 259
Query: 242 -NKIQIYPPPSREELRRRFIAATEN---------ALELISGMMIMNPKKRWDAVKCLQSQ 291
YP EEL +I +E+ A +L+S M++++P KR + L+
Sbjct: 260 VENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHP 319
Query: 292 YFQELPEP 299
Y +P
Sbjct: 320 YITVWYDP 327
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 134 bits (337), Expect = 2e-31
Identities = 104/308 (33%), Positives = 154/308 (49%), Gaps = 24/308 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + K G G +V G ++AVK++ A RE+ L+ + H N+
Sbjct: 26 YQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I M + S++L L G+ H
Sbjct: 86 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TACTNFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-SFSNY 241
Y VDIWSVG I AE++L PG+D +DQ N LGTP+ ++ + NY
Sbjct: 200 MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNY 259
Query: 242 -NKIQIYPPPSREELRRRFIAATEN---------ALELISGMMIMNPKKRWDAVKCLQSQ 291
YP EEL +I +E+ A +L+S M++++P KR + L+
Sbjct: 260 VENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHP 319
Query: 292 YFQELPEP 299
Y +P
Sbjct: 320 YITVWYDP 327
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 134 bits (336), Expect = 2e-31
Identities = 77/238 (32%), Positives = 125/238 (52%), Gaps = 13/238 (5%)
Query: 3 LKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQ 62
L+ + Y + G G + +V + S+ + +A+K++ + L LRE++ L+
Sbjct: 75 LERAAETYEPTQNIGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLARRTLREIRVLR 134
Query: 63 ELKHVNVIELVDVFMANDNLN----LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLR 118
+ H N++ L D+F L LV++ + +L II I +++ LR
Sbjct: 135 YINHPNIVPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLR 194
Query: 119 GVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE---------ILTSNVV 169
G+ + H I HRDLKP+NLL+ DG L+IADFG+A+ + + +T +V
Sbjct: 195 GLEYLHAACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHVA 254
Query: 170 TRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTP 227
T YRAPELLF +++AVD+W+VG IF E+++R LPG+ QI + LG P
Sbjct: 255 TLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQP 312
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 132 bits (331), Expect = 8e-31
Identities = 83/261 (31%), Positives = 137/261 (51%), Gaps = 27/261 (10%)
Query: 56 REVKFLQELKHVNVIELVDVFMAND------NLNLVLEFLPADLEIIIKDTSIM------ 103
RE++ ++ + H N+I+L+ F ++ +L L+LE++P E + D
Sbjct: 34 RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMP---ETVFDDMRWYTRRRKS 90
Query: 104 FSPADIKSWILMTLRGVHHCHRNFILHRDLKPNNLLLA-PDGQLKIADFGLARLMASPQE 162
IK + R + + H + HRD+KP NLL+ G LK+ DFG A+++ P E
Sbjct: 91 IPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLV-PSE 149
Query: 163 ILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFR 222
S + +R+YRAPEL+FGA HYT+ +D+WS + AEL + P PG V+Q+ R
Sbjct: 150 PNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIR 209
Query: 223 ALGTPTDADWPEVS----SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNP 278
LGTP+ + E+S ++ N++ + P + T+NA++L+ M+ P
Sbjct: 210 VLGTPS---YHEISVMNPNYVNHSLPNVRPHTLESVMPHN---CTKNAMDLLHKMLTYVP 263
Query: 279 KKRWDAVKCLQSQYFQELPEP 299
KR A++ L +F EL +P
Sbjct: 264 SKRISAIEVLTHPFFDELRDP 284
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 131 bits (329), Expect = 1e-30
Identities = 96/306 (31%), Positives = 150/306 (48%), Gaps = 33/306 (10%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + G G +V T +++A+K++ A RE K ++ + H N+
Sbjct: 24 YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNI 83
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++ F NL LV+E + A+L +I+ M D S++L L G+ H
Sbjct: 84 IGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ----MDLDHDRMSYLLYQMLCGIKH 139
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 140 LHSAGIIHRDLKPSNIVVKADCTLKILDFGLAR-TAGTTFMMTPYVVTRYYRAPEVILG- 197
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
YT VDIWSVG I E++ PG D +DQ N LGTP+ + +
Sbjct: 198 MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNY 257
Query: 237 ----------SFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVK 286
SF ++P + + RR+ +A L+S M++++P++R +
Sbjct: 258 VENRPRYTGYSFDRLFPDGLFPNDNNQNSRRK----ASDARNLLSKMLVIDPEQRISVDE 313
Query: 287 CLQSQY 292
L+ +Y
Sbjct: 314 ALKHEY 319
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 130 bits (326), Expect = 3e-30
Identities = 92/292 (31%), Positives = 145/292 (49%), Gaps = 24/292 (8%)
Query: 34 RSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVFMAND-----NLNLVLEF 88
R +A+K+++ F RE K LQ ++H N+I +D++ ++ ++ +V EF
Sbjct: 145 RYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEF 204
Query: 89 LPADLEIIIKDTSI----MFSPADIKSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDG 144
L I+K + + IK I +R + + H I+HRDLKP NL L D
Sbjct: 205 AGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDS 264
Query: 145 QLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF-GAKHYTSAVDIWSVGVIFAELML 203
L I DFGLAR + LT V TRWYR+PE+++ YT+ D+WS+G I AEL+
Sbjct: 265 DLMILDFGLARSLEKKDTSLTQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLT 324
Query: 204 RIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK------IQIYPPPSREELRR 257
P PG + Q + G+P D ++ N N IQ Y R R
Sbjct: 325 GEPLFPGDEPNAQYQRITQLCGSP---DEELLTKIENDNSSAIKAVIQSYTTHKRRNFRD 381
Query: 258 RFIA--ATENALELISGMMIMNPKKRWDAVKCLQSQYFQELPEPTLPQDLPK 307
F A +E+ ++L+ +++++P+KR + +Q Y L E +LP+D P+
Sbjct: 382 VFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPY---LAEFSLPEDEPR 430
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 129 bits (324), Expect = 5e-30
Identities = 89/302 (29%), Positives = 154/302 (50%), Gaps = 23/302 (7%)
Query: 6 TVD-DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQE 63
T+D Y + G G++ VV T + +A+K++ + ++K+ RE++ ++
Sbjct: 159 TIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKN-------RELETMKM 211
Query: 64 LKHVNVIELVDVFMANDN-----LNLVLEFLPADLEIIIK---DTSIMFSPADIKSWILM 115
L H N + L F D LNLVL+++P L ++ + + +IK +
Sbjct: 212 LCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQ 271
Query: 116 TLRGVHHCHR-NFILHRDLKPNNLLLAPDG-QLKIADFGLARLMASPQEILTSNVVTRWY 173
+ +++ H I HRD+KP NLL+ P KI DFG A+ + P + S + +R+Y
Sbjct: 272 LFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCL-KPDQPNVSYICSRYY 330
Query: 174 RAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWP 233
RAPEL+FGA +Y++ VD+WS + AEL+L P G+ +DQ+ + +G PT
Sbjct: 331 RAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTK---D 387
Query: 234 EVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYF 293
E+S + + ++P L F A + L+L++ + +P +R ++CL S YF
Sbjct: 388 EISGMNPNYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYF 447
Query: 294 QE 295
E
Sbjct: 448 DE 449
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 129 bits (324), Expect = 5e-30
Identities = 73/195 (37%), Positives = 104/195 (52%), Gaps = 4/195 (2%)
Query: 109 IKSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLAR-LMASPQE---IL 164
++ ++ LRG+ + H ++HRDLKP+NLL+ + +LKI DFG+AR L SP E +
Sbjct: 20 VRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFM 79
Query: 165 TSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRAL 224
T V TRWYRAPEL+ YT A+D+WSVG IF E++ R PGK+ V Q+ + L
Sbjct: 80 TEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVL 139
Query: 225 GTPTDADWPEVSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDA 284
GTP+ A V + IQ PP + A AL L+ M+ P R A
Sbjct: 140 GTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISA 199
Query: 285 VKCLQSQYFQELPEP 299
L+ + + +P
Sbjct: 200 AAALRHPFLAKYHDP 214
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 128 bits (322), Expect = 9e-30
Identities = 78/247 (31%), Positives = 123/247 (49%), Gaps = 26/247 (10%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQEL-KHV 67
Y ++ G+G Y +V+ + TG +A+K+I + F+D D RE+ LQE H
Sbjct: 13 YLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDA-FRDKTDAQRTFREITLLQEFGDHP 71
Query: 68 NVIELVDVFMANDN--LNLVLEFL--------PADLEIIIKDTSI--------MFSPADI 109
N+I L+DV A ++ + LV EF+ P + + DT + + +
Sbjct: 72 NIISLLDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAVIRKGGLLQDVHV 131
Query: 110 KSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQE-----IL 164
+S LR H ++HRD KP+N+LL + +K+ DFGLAR + E +
Sbjct: 132 RSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAV 191
Query: 165 TSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRAL 224
T V TRWYRAPE+L + YT VD+WS+G I E++ P PG + Q+ + +
Sbjct: 192 TEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETI 251
Query: 225 GTPTDAD 231
P++ D
Sbjct: 252 PPPSEED 258
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 127 bits (320), Expect = 2e-29
Identities = 102/308 (33%), Positives = 150/308 (48%), Gaps = 24/308 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + K G G +V G ++AVK++ A RE+ L+ + H N+
Sbjct: 26 YQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I M + S++L L G+ H
Sbjct: 86 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TACTNFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-SFSNY 241
Y VDIWSVG I EL+ G D +DQ N LGTP+ ++ + NY
Sbjct: 200 MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNY 259
Query: 242 -NKIQIYPPPSREELRRRFIAATEN---------ALELISGMMIMNPKKRWDAVKCLQSQ 291
YP EEL +I +E+ A +L+S M++++P KR + L+
Sbjct: 260 VENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHP 319
Query: 292 YFQELPEP 299
Y +P
Sbjct: 320 YITVWYDP 327
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 127 bits (320), Expect = 2e-29
Identities = 102/308 (33%), Positives = 150/308 (48%), Gaps = 24/308 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + K G G +V G ++AVK++ A RE+ L+ + H N+
Sbjct: 26 YQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I M + S++L L G+ H
Sbjct: 86 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TACTNFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-SFSNY 241
Y VDIWSVG I EL+ G D +DQ N LGTP+ ++ + NY
Sbjct: 200 MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNY 259
Query: 242 -NKIQIYPPPSREELRRRFIAATEN---------ALELISGMMIMNPKKRWDAVKCLQSQ 291
YP EEL +I +E+ A +L+S M++++P KR + L+
Sbjct: 260 VENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHP 319
Query: 292 YFQELPEP 299
Y +P
Sbjct: 320 YITVWYDP 327
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 127 bits (320), Expect = 2e-29
Identities = 102/308 (33%), Positives = 150/308 (48%), Gaps = 24/308 (7%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + K G G +V G ++AVK++ A RE+ L+ + H N+
Sbjct: 26 YQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I M + S++L L G+ H
Sbjct: 86 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TACTNFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-SFSNY 241
Y VDIWSVG I EL+ G D +DQ N LGTP+ ++ + NY
Sbjct: 200 MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNY 259
Query: 242 -NKIQIYPPPSREELRRRFIAATEN---------ALELISGMMIMNPKKRWDAVKCLQSQ 291
YP EEL +I +E+ A +L+S M++++P KR + L+
Sbjct: 260 VENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHP 319
Query: 292 YFQELPEP 299
Y +P
Sbjct: 320 YITVWYDP 327
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 127 bits (319), Expect = 2e-29
Identities = 89/291 (30%), Positives = 142/291 (48%), Gaps = 10/291 (3%)
Query: 9 DYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELK-HV 67
+Y K GEGT++ V G A K++K +F+ ++ LRE++ L+ L H
Sbjct: 3 NYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMK-QRFESIEQVNNLREIQALRRLNPHP 61
Query: 68 NVIELVDVFM--ANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
N++ L +V + +L L+ E + ++ +I+ S I ++ + + H HR
Sbjct: 62 NILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHR 121
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
N I HRD+KP N+L+ D LK+ DFG R + S Q T + TRWYRAPE L Y
Sbjct: 122 NGIFHRDVKPENILIKQD-VLKLGDFGSCRSVYSKQPY-TEYISTRWYRAPECLLTDGFY 179
Query: 186 TSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQ 245
T +D+WS G +F E+ P PG +++DQI+ +GTP ++ F +
Sbjct: 180 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQ---KILTKFKQSRAMN 236
Query: 246 I-YPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
+P + + L L+ M+ +P +R A + LQ YFQE
Sbjct: 237 FDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 126 bits (317), Expect = 3e-29
Identities = 93/323 (28%), Positives = 165/323 (50%), Gaps = 27/323 (8%)
Query: 8 DDYTKEKKAGEGTYAVVYLGTKKSTG---RSIAVKEIK-TSQFKDGLDMSALREVKFLQE 63
D Y ++K G+G++ VYL +K ++AVK++K +S+ K ++ LRE L++
Sbjct: 19 DRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRK 78
Query: 64 L-KHVNVIELVDVFM-ANDNLNLVLEFLPADL-EIIIKDTSIMFSPADIKSWILMTLRGV 120
+ KH +I+L++ FM N+ LV+EF+ +L ++ + +F+ + +L + G+
Sbjct: 79 ISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGI 138
Query: 121 HHCHRNFILHRDLKPNNLL--------LAPDGQLKIADFGLARLMASPQEILTSNVVTRW 172
H H++ +HRD+KP N+L ++ +K+ DFGLAR S + LT V TRW
Sbjct: 139 EHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVS-SDPLTEYVSTRW 197
Query: 173 YRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTP----- 227
YRAPELL + Y +VD+++ G I E+ P PG+++ DQ+N LG P
Sbjct: 198 YRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRNETDQLNRVCEILGNPGIDEL 257
Query: 228 -TDADWPEVSSFSNYNKIQIYPPPSREELRRRFIA--ATENALELISGMMIMNPKKRWDA 284
T W + + ++ PP++ ++ + E ++I ++ NP R A
Sbjct: 258 DTLHYWSQAKELA--KRLGFMLPPTKPYPIQKLLPQNCPEGHAKMIPCLLAWNPDVRPTA 315
Query: 285 VKCLQSQYFQELPEPTLPQDLPK 307
C + +F P + +P+
Sbjct: 316 KYC-KEVFFPLPPSASKSNSVPQ 337
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 125 bits (315), Expect = 6e-29
Identities = 96/322 (29%), Positives = 153/322 (46%), Gaps = 38/322 (11%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V R++A+K++ A RE+ ++ + H N+
Sbjct: 26 YQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF +L +V+E + A+L +I+ M + S++L L G+ H
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGTSFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
Y VD+WSVG I E++ PG+D +DQ N LGTP ++
Sbjct: 200 MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTY 259
Query: 237 -----SFSNYNKIQIYPP---PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
++ Y+ +++P P+ E + A +L+S M++++ KR + L
Sbjct: 260 VENRPKYAGYSFEKLFPDVLFPADSEHNK---LKASQARDLLSKMLVIDASKRISVDEAL 316
Query: 289 QSQYFQ--------ELPEPTLP 302
Q Y E P P +P
Sbjct: 317 QHPYINVWYDPSEAEAPPPKIP 338
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 125 bits (315), Expect = 6e-29
Identities = 96/322 (29%), Positives = 153/322 (46%), Gaps = 38/322 (11%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V R++A+K++ A RE+ ++ + H N+
Sbjct: 26 YQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF +L +V+E + A+L +I+ M + S++L L G+ H
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGTSFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
Y VD+WSVG I E++ PG+D +DQ N LGTP ++
Sbjct: 200 MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTY 259
Query: 237 -----SFSNYNKIQIYPP---PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
++ Y+ +++P P+ E + A +L+S M++++ KR + L
Sbjct: 260 VENRPKYAGYSFEKLFPDVLFPADSEHNK---LKASQARDLLSKMLVIDASKRISVDEAL 316
Query: 289 QSQYFQ--------ELPEPTLP 302
Q Y E P P +P
Sbjct: 317 QHPYINVWYDPSEAEAPPPKIP 338
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 125 bits (313), Expect = 1e-28
Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 38/322 (11%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V R++A+K++ A RE+ ++ + H N+
Sbjct: 26 YQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF +L +V+E + A+L +I+ M + S++L L G+ H
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGTSFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
Y VDIWSVG I E++ PG D +DQ N LGTP ++
Sbjct: 200 MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTY 259
Query: 237 -----SFSNYNKIQIYPP---PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
++ Y+ +++P P+ E + A +L+S M++++ KR + L
Sbjct: 260 VENRPKYAGYSFEKLFPDVLFPADSEHNK---LKASQARDLLSKMLVIDASKRISVDEAL 316
Query: 289 QSQYFQ--------ELPEPTLP 302
Q Y E P P +P
Sbjct: 317 QHPYINVWYDPSEAEAPPPKIP 338
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 125 bits (313), Expect = 1e-28
Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 38/322 (11%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V R++A+K++ A RE+ ++ + H N+
Sbjct: 26 YQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF +L +V+E + A+L +I+ M + S++L L G+ H
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGTSFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
Y VDIWSVG I E++ PG D +DQ N LGTP ++
Sbjct: 200 MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTY 259
Query: 237 -----SFSNYNKIQIYPP---PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
++ Y+ +++P P+ E + A +L+S M++++ KR + L
Sbjct: 260 VENRPKYAGYSFEKLFPDVLFPADSEHNK---LKASQARDLLSKMLVIDASKRISVDEAL 316
Query: 289 QSQYFQ--------ELPEPTLP 302
Q Y E P P +P
Sbjct: 317 QHPYINVWYDPSEAEAPPPKIP 338
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 124 bits (312), Expect = 1e-28
Identities = 95/311 (30%), Positives = 147/311 (46%), Gaps = 30/311 (9%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V R++A+K++ A RE+ ++ + H N+
Sbjct: 64 YQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 123
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I+ M + S++L L G+ H
Sbjct: 124 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKH 179
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 180 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGTSFMMTPYVVTRYYRAPEVILG- 237
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
Y VDIWSVG I E++ PG+D +DQ N LGTP ++
Sbjct: 238 MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNY 297
Query: 237 -----SFSNYNKIQIYPP---PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
++ +++P P+ E + A +L+S M++++P KR L
Sbjct: 298 VENRPKYAGLTFPKLFPDSLFPADSEHNK---LKASQARDLLSKMLVIDPAKRISVDDAL 354
Query: 289 QSQYFQELPEP 299
Q Y +P
Sbjct: 355 QHPYINVWYDP 365
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 124 bits (312), Expect = 1e-28
Identities = 95/311 (30%), Positives = 147/311 (46%), Gaps = 30/311 (9%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V R++A+K++ A RE+ ++ + H N+
Sbjct: 64 YQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 123
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I+ M + S++L L G+ H
Sbjct: 124 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKH 179
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 180 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGTSFMMTPYVVTRYYRAPEVILG- 237
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
Y VDIWSVG I E++ PG+D +DQ N LGTP ++
Sbjct: 238 MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNY 297
Query: 237 -----SFSNYNKIQIYPP---PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
++ +++P P+ E + A +L+S M++++P KR L
Sbjct: 298 VENRPKYAGLTFPKLFPDSLFPADSEHNK---LKASQARDLLSKMLVIDPAKRISVDDAL 354
Query: 289 QSQYFQELPEP 299
Q Y +P
Sbjct: 355 QHPYINVWYDP 365
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 124 bits (312), Expect = 1e-28
Identities = 95/311 (30%), Positives = 147/311 (46%), Gaps = 30/311 (9%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V R++A+K++ A RE+ ++ + H N+
Sbjct: 26 YQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I L++VF L LV+E + A+L +I+ M + S++L L G+ H
Sbjct: 86 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKH 141
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-TAGTSFMMTPYVVTRYYRAPEVILG- 199
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS------ 236
Y VDIWSVG I E++ PG+D +DQ N LGTP ++
Sbjct: 200 MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNY 259
Query: 237 -----SFSNYNKIQIYPP---PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCL 288
++ +++P P+ E + A +L+S M++++P KR L
Sbjct: 260 VENRPKYAGLTFPKLFPDSLFPADSEHNK---LKASQARDLLSKMLVIDPAKRISVDDAL 316
Query: 289 QSQYFQELPEP 299
Q Y +P
Sbjct: 317 QHPYINVWYDP 327
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 124 bits (311), Expect = 2e-28
Identities = 79/229 (34%), Positives = 127/229 (54%), Gaps = 11/229 (4%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSI-AVKEIKTSQFKDGLDMSALREVKFLQEL-KHV 67
Y +K G+GT+ VYL T K+ + + A+K +K K D + LREV L L ++
Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVS-DATRLREVHSLLRLSENE 94
Query: 68 NVIELVDVFMANDN-LNLVLEFLPADL-EIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
N++ + D+++ L++V+EFL +L ++I + + ++ + +G++H H
Sbjct: 95 NIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHT 154
Query: 126 NFILHRDLKPNNLLLAPDGQ-----LKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
N HRD+KP N+L++ + +KIADFGLAR + S + T V TRWYRAPELL
Sbjct: 155 NGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINS-RPPYTEYVSTRWYRAPELLL 213
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTD 229
+Y+ VDI++ G + E+ P PG DD DQ+ LG+P +
Sbjct: 214 RDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDE 262
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 122 bits (305), Expect = 9e-28
Identities = 89/298 (29%), Positives = 143/298 (47%), Gaps = 31/298 (10%)
Query: 19 GTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVFMA 78
G V + T + +A+K+++ A RE L +KH N+I L++ F
Sbjct: 47 GAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTP 106
Query: 79 NDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHRD 132
+ +L+ LV+E + +L +I + + ++ +L + H H + ++HRD
Sbjct: 107 DTSLSTFREVYLVMELMTHNLHEVIH--RLRLDHKTLSFFVYQSLCAIKHLHNSGVIHRD 164
Query: 133 LKPNNLLLAPDGQLKIADFGLARLMASPQEILTSN-VVTRWYRAPELLFGAKHYTSAVDI 191
LKP+N+++ LK+ DFGLAR + S+ VVTR+YRAPE++ G Y+ VDI
Sbjct: 165 LKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGLP-YSEKVDI 223
Query: 192 WSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPS 251
WSVG IFAE++ PGKD +DQ + LGTP D +S + + P
Sbjct: 224 WSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDD---HFISQLGQSAAMYVRSLP- 279
Query: 252 REELR--------RRFIAATEN---------ALELISGMMIMNPKKRWDAVKCLQSQY 292
R + R F+ TEN A +L+ M+ +NP++R+ L Y
Sbjct: 280 RHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPY 337
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 120 bits (302), Expect = 2e-27
Identities = 94/302 (31%), Positives = 149/302 (49%), Gaps = 37/302 (12%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELK 65
+ +Y K GEG++ V L +TG+ +A+K I K K + RE+ +L+ L+
Sbjct: 52 IGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR 111
Query: 66 HVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
H ++I+L DV + D + +V+E+ +L I M S + + + + V +CHR
Sbjct: 112 HPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKM-SEQEARRFFQQIISAVEYCHR 170
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
+ I+HRDLKP NLLL +KIADFGL+ +M + TS + Y APE++ G +
Sbjct: 171 HKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTS-CGSPNYAAPEVISGKLYA 229
Query: 186 TSAVDIWSVGVI-FAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKI 244
VD+WS GVI + L R+P+ D + I V F+ + N +
Sbjct: 230 GPEVDVWSCGVILYVMLCRRLPF-----DDESIPVLFKNIS----------------NGV 268
Query: 245 QIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ-ELPEPTLPQ 303
P +F+ + A LI M+I+NP R + +Q +F+ +LPE LP
Sbjct: 269 YTLP---------KFL--SPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPP 317
Query: 304 DL 305
DL
Sbjct: 318 DL 319
>CE20405 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 119 bits (298), Expect = 6e-27
Identities = 97/314 (30%), Positives = 146/314 (45%), Gaps = 43/314 (13%)
Query: 19 GTYAVVYLGTKKS-TGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL---KHVNVIELVD 74
G ++ VY G ++ + + I + KT G M EVK L +L KH N++ L+
Sbjct: 35 GAFSNVYRGVAQTESNQEIDIVIKKTWPRHKGCPM----EVKILGQLGKLKHRNIVRLLY 90
Query: 75 VFMANDN----LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILH 130
+ L L+ E++P +L +KD + ++K + RG H + I H
Sbjct: 91 SYQKQHEGRICLALIFEYIPLNLYQFLKDKNRRIDIVEVKLIVWQLFRGQAHLEKADICH 150
Query: 131 RDLKPNNLLL-APDGQLKIADFGLARLMA--SPQEILTSNVVTRWYRAPELLFGAKHYTS 187
RD+KP NLL A G LKI+DFG + + + SPQ+ S VTR+YR PEL+ G+K+Y
Sbjct: 151 RDIKPQNLLYNAETGLLKISDFGSSSIQSTKSPQQ---SYHVTRYYRPPELILGSKYYGC 207
Query: 188 AVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDAD----------WPEVSS 237
+D WS G +F EL+ L GK +Q V F LG PTD+D EV
Sbjct: 208 KIDTWSCGCVFGELLKGGIILAGKSSNNQAEVIFDMLGYPTDSDVSSMKVSSTKLQEVLD 267
Query: 238 FSNYNKIQ-------------IYPPPSREELRRRFIAATE--NALELISGMMIMNPKKRW 282
YNK + IY R + I + ++ ++ +++ NP KR
Sbjct: 268 SYEYNKSKTTADLTYLYTQTVIYQKDRRTTVYNTKIEQDDMKESVAVLLQILVYNPNKRL 327
Query: 283 DAVKCLQSQYFQEL 296
++ L YF L
Sbjct: 328 SGIEILTHPYFNVL 341
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 119 bits (297), Expect = 7e-27
Identities = 72/201 (35%), Positives = 116/201 (56%), Gaps = 4/201 (1%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALR-EVKFLQELK 65
V+DY + GEG++ VY G +K TG+++A+K I Q K D+ +LR E++ L++LK
Sbjct: 3 VEDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIM-KQGKTDKDIHSLRQEIEILRKLK 61
Query: 66 HVNVIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHR 125
H N+IE++D F +V EF +L I++D + +++ ++ + + H
Sbjct: 62 HENIIEMLDSFENAREFCVVTEFAQGELFEILEDDKCL-PEEQVQAIAKQLVKALDYLHS 120
Query: 126 NFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHY 185
N I+HRD+KP N+L+ +K+ DFG AR M++ +L S T Y APEL+ + Y
Sbjct: 121 NRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELV-KEQPY 179
Query: 186 TSAVDIWSVGVIFAELMLRIP 206
VD+WS+GVI EL + P
Sbjct: 180 DRTVDLWSLGVILYELYVGQP 200
>CE01612 [G] KOG0658 Glycogen synthase kinase-3
Length = 410
Score = 117 bits (294), Expect = 2e-26
Identities = 78/234 (33%), Positives = 121/234 (51%), Gaps = 7/234 (2%)
Query: 4 KSTVDDYTKEKKAGEGTYAVVYLGTKKST-GRSIAVKEIKTSQFKDGLDMSALREVKFLQ 62
K+T + K G G ++ VY G S + +AVK + + L S E++ L
Sbjct: 21 KTTKKAISAHKLCGSGRFSNVYCGQMISPIEKEVAVKNVWSDTETRHLATSEYPEIQILS 80
Query: 63 ELKHVNVIELVDVFMANDN---LN-LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLR 118
+L H + L+ + N N +N LVL++LP DL + +D + F D K +
Sbjct: 81 KLFHPAISNLLYFYSRNANDKVINCLVLDYLPQDLARL-RDQGVKFDVLDAKLYTFQLFC 139
Query: 119 GVHHCHRNFILHRDLKPNNLLL-APDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPE 177
+ H I+H D+KP N+++ G+LK+ADFG AR + + ++ ++ VTR+YR PE
Sbjct: 140 AISHLTSKNIVHMDIKPQNVVMDRMAGRLKLADFGNARRLETNEKTGSAYQVTRFYRPPE 199
Query: 178 LLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDAD 231
LLFG + +T+++DIWS + EL GKD DQI + G PTD D
Sbjct: 200 LLFGCEKFTASIDIWSATCVAFELFANRVLFKGKDTKDQIVLITGVFGYPTDDD 253
>CE05377 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 117 bits (293), Expect = 2e-26
Identities = 91/313 (29%), Positives = 149/313 (47%), Gaps = 41/313 (13%)
Query: 19 GTYAVVYLG---TKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDV 75
G ++ VY G T+ + I +K+ L++ L + L +LKH N++ L+
Sbjct: 35 GAFSNVYRGIARTESNHQMEIVIKKTWPRHKGCPLEVKILGK---LGKLKHKNIVRLLFS 91
Query: 76 FMANDN----LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHR 131
+ L L+ E++P +L +KD + ++K + RG H ++ I HR
Sbjct: 92 YQKQHEGRICLGLIFEYIPMNLHQFLKDNNRRVDIIEVKLIVWQLFRGQAHLEKSEICHR 151
Query: 132 DLKPNNLLLAPD-GQLKIADFGLARL--MASPQEILTSNVVTRWYRAPELLFGAKHYTSA 188
D+KP NLL D G LKI+D+G + + + +PQ+ S VTR+YR PELL G+K+Y
Sbjct: 152 DIKPQNLLYNADTGLLKISDYGSSAIESVKTPQQ---SYHVTRYYRPPELLLGSKNYGCK 208
Query: 189 VDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPT--DADWPEVSSFSNYNKIQI 246
+D WS G +F EL+ +L GK +Q V F G PT D VS+ IQ
Sbjct: 209 IDTWSCGCVFGELLKGGIFLAGKSAKNQAEVVFDMFGVPTAEDVSSMNVSNTKYKEIIQS 268
Query: 247 YPPPSREEL----------------RRRFIAAT-------ENALELISGMMIMNPKKRWD 283
Y P + + RR + T ++++EL+ +++ NP +R
Sbjct: 269 YEPDTSKRTADLAYLYNQTASFQRDRRSTVYNTKIDYSDMKDSVELLRQVLVYNPSRRLC 328
Query: 284 AVKCLQSQYFQEL 296
++ L + +F L
Sbjct: 329 GIEFLTNPFFTVL 341
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 115 bits (287), Expect = 1e-25
Identities = 95/320 (29%), Positives = 149/320 (45%), Gaps = 31/320 (9%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y + G G +V +A+K++ A RE+K + + H N+
Sbjct: 119 YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNI 178
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWIL-MTLRGVHH 122
I +++ F L+ +V+E + A+L +I+ M + S++L L G+ H
Sbjct: 179 IGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ----MDLDHERLSYLLYQMLCGIRH 234
Query: 123 CHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGA 182
H I+HRDLKP+N+++ D LKI DFGLAR A ++T VVTR+YRAPE++ G
Sbjct: 235 LHSAGIIHRDLKPSNIVVRSDCTLKILDFGLAR-TAIEAFMMTPYVVTRYYRAPEVILG- 292
Query: 183 KHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVS-SFSNY 241
Y VD+WS+G IF EL+ PG D +DQ LGTP + + + NY
Sbjct: 293 MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNY 352
Query: 242 --NKIQIYPPPSREELRRRFIAATEN--------ALELISGMMIMNPKKRWDAVKCLQSQ 291
N+ + P T + A +L+S M++++P++R L+
Sbjct: 353 VENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHP 412
Query: 292 Y----FQEL---PEPTLPQD 304
Y F E+ P LP D
Sbjct: 413 YVNVWFDEIEVYAPPPLPYD 432
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 114 bits (286), Expect = 1e-25
Identities = 80/302 (26%), Positives = 148/302 (48%), Gaps = 25/302 (8%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G G +V+ + +A+K+I + + ALRE+K ++ L H N+
Sbjct: 20 YMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSV--KHALREIKIIRRLDHDNI 77
Query: 70 IELVDVFMAN--------------DNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILM 115
+++ ++ + +++ +V E++ DL +++ ++ A + ++
Sbjct: 78 VKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARL--FMYQ 135
Query: 116 TLRGVHHCHRNFILHRDLKPNNLLL-APDGQLKIADFGLARLMA---SPQEILTSNVVTR 171
LRG+ + H +LHRDLKP NL + D LKI DFGLAR+M S + L+ +VT+
Sbjct: 136 LLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTK 195
Query: 172 WYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDAD 231
WYR+P LL +YT A+D+W+ G IFAE++ G +++Q+ + ++ + D
Sbjct: 196 WYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEED 255
Query: 232 WPE-VSSFSNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQS 290
E +S Y + + P + L + + AL+ + ++ +P R A + L
Sbjct: 256 RQELLSVIPVYIRNDMTEP--HKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSH 313
Query: 291 QY 292
Y
Sbjct: 314 PY 315
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 114 bits (284), Expect = 2e-25
Identities = 85/284 (29%), Positives = 132/284 (45%), Gaps = 34/284 (11%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNVIELVDVF 76
G G + V+ T+KSTG +A K IK KD D+ E+ + +L HVN+I+L D F
Sbjct: 498 GGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVK--NEINIMNQLSHVNLIQLYDAF 555
Query: 77 MANDNLNLVLEFLPA-DLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHRDLKP 135
+ + LV+E++ +L I D + D+ + GVH+ H+++ILH DLKP
Sbjct: 556 ESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKP 615
Query: 136 NNLLLA--PDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWS 193
N+L Q+KI DFGLAR P+E L N T + APE++ + + D+WS
Sbjct: 616 ENILCVNQTGHQIKIIDFGLAR-RYKPREKLKVNFGTPEFLAPEVV-NYEFVSFPTDMWS 673
Query: 194 VGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPPPSRE 253
VGVI L+ + G+ D + +N DAD
Sbjct: 674 VGVITYMLLSGLSPFLGETDAETMNFIVNC-SWDFDAD---------------------- 710
Query: 254 ELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQELP 297
F +E A + +S +++ R A +CL+ ++ LP
Sbjct: 711 ----TFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLP 750
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 113 bits (283), Expect = 3e-25
Identities = 85/312 (27%), Positives = 145/312 (46%), Gaps = 38/312 (12%)
Query: 17 GEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMS-ALREVKFLQELKHVNVIELVDV 75
G G +V R +AVK+I S D M ALRE+K ++ L H N++++ +V
Sbjct: 27 GFGVNGLVLSAVDSRACRKVAVKKIALS---DARSMKHALREIKIIRRLDHDNIVKVYEV 83
Query: 76 FMANDN-----------LNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCH 124
+V E++ DL +++ ++ A K ++ LRG+ + H
Sbjct: 84 LGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEEHA--KLFMYQLLRGLKYIH 141
Query: 125 RNFILHRDLKPNNLLLAP-DGQLKIADFGLARLMA---SPQEILTSNVVTRWYRAPELLF 180
+LHRDLKP N+ ++ D LKI DFGLAR++ S + L+ +VT+WYR+P LL
Sbjct: 142 SANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLL 201
Query: 181 GAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSN 240
+YT A+D+W+ G I AE++ G +++Q+ + + + D E+
Sbjct: 202 SPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDEL----- 256
Query: 241 YNKIQIYPP------PSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQ 294
+++ P + LR+ A++ + ++ NP R A LQ Y
Sbjct: 257 ---LRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMS 313
Query: 295 ELPEPTLPQDLP 306
+ P+D P
Sbjct: 314 PY---SCPEDEP 322
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 112 bits (280), Expect = 7e-25
Identities = 72/220 (32%), Positives = 119/220 (53%), Gaps = 27/220 (12%)
Query: 51 DMSALREVKFLQELK-HVNVIELVDVFMANDN--LNLVLEFLPADLEIIIKDTSI-MFSP 106
D + +RE+KF+ + + ++I++ +VF+ ++N L++V+E + +L ++K +FS
Sbjct: 108 DYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSI 167
Query: 107 ADIKSWILMTLRGVHHCHRNFILHRDLKPNNLLLAPDGQ-----------------LKIA 149
+KS + L G+ H H + HRDLKP N+L+ P Q +K+A
Sbjct: 168 PSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLA 227
Query: 150 DFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLP 209
DFGLAR + + T+ V TRWYR+PE+L + +Y+ +DIW+ G + E+ + P
Sbjct: 228 DFGLARHVENKNPY-TAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFP 286
Query: 210 GKDDVDQINVTFRALGTPTDADWPEVSSFSNYNKIQIYPP 249
G +++DQI LGTP + S F N N I PP
Sbjct: 287 GANEIDQIWKILEVLGTPI-----KRSDFVNTNHITAPPP 321
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 112 bits (280), Expect = 7e-25
Identities = 91/323 (28%), Positives = 144/323 (44%), Gaps = 37/323 (11%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
Y K G +V + T + +A+K+++ A RE L LKH N+
Sbjct: 29 YVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFILLTTLKHPNI 88
Query: 70 IELVDVFMANDNLN------LVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
I L++ F + +L+ LV+EF+ +L +I + + + +L + H
Sbjct: 89 IRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIH--RLRLDHETLSFLVYQSLCAIKHL 146
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H +HRDLKP+N+++ LK+ DFGLAR + ++ V TR+YRAPE++ G
Sbjct: 147 HNLGFIHRDLKPSNIVVNERCVLKVLDFGLAR-RRNVDMRMSDYVGTRYYRAPEVILGL- 204
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFSNYNK 243
+Y+ VDIWSVG I AE++ PGKD DQ L TP D ++
Sbjct: 205 NYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHFINQLEPIG---- 260
Query: 244 IQIYPPPSREELRR---------RFIAATEN---------ALELISGMMIMNPKKRWDAV 285
+Y + L R F+ TEN A +L+ M+ +NP++R+
Sbjct: 261 -AVYVRSLPQHLARAFNEIVPDSNFLPETENPKDHLTLHMARDLLFNMLKINPEERYSVE 319
Query: 286 KCLQSQYFQE----LPEPTLPQD 304
L Y + P +P D
Sbjct: 320 DALNHPYTMDDEVNAPASEIPDD 342
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 111 bits (278), Expect = 1e-24
Identities = 90/296 (30%), Positives = 136/296 (45%), Gaps = 37/296 (12%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
STV ++ G G + +VY G + TGR +A+K I +F + EV LQ L
Sbjct: 578 STVYQIFPDEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNL 637
Query: 65 KHVNVIELVDVFMANDNLNLVLEFLPAD-LEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H V+ L +F + + +V+E L D LE+I+ K I L + H
Sbjct: 638 HHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHL 697
Query: 124 HRNFILHRDLKPNNLLLA---PDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
H I+H DLKP N+LLA P Q+K+ DFG AR++ + S V T Y APE+L
Sbjct: 698 HFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGE-KSFRRSVVGTPAYLAPEVLR 756
Query: 181 GAKHYTSAVDIWSVGV-IFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
K Y ++D+WSVGV I+ L P+ +D DQI
Sbjct: 757 N-KGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQ--------------------- 794
Query: 240 NYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
N +YPP +E+ + A++LI+ ++ + +KR+ K L + Q+
Sbjct: 795 --NAAFMYPPNPWKEI-------SHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQD 841
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 110 bits (275), Expect = 3e-24
Identities = 90/297 (30%), Positives = 136/297 (45%), Gaps = 39/297 (13%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
+TV ++ G G + VVY G + TGR +AVK I +F + EV LQ L
Sbjct: 546 ATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSL 605
Query: 65 KHVNVIELVDVFMANDNLNLVLEFLPAD-LEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
+H ++ L +F + + +V+E L D LE+I+ K I L + H
Sbjct: 606 RHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHL 665
Query: 124 HRNFILHRDLKPNNLLLA---PDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
H I+H DLKP N+LLA P Q+K+ DFG AR++ + S V T Y APE+L
Sbjct: 666 HFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGE-KSFRRSVVGTPAYLAPEVLL 724
Query: 181 GAKHYTSAVDIWSVGVI-FAELMLRIPYLPGKDDVDQI-NVTFRALGTPTDADWPEVSSF 238
+ Y ++D+WSVGVI + L P+ +D DQI N F +P W +S+
Sbjct: 725 N-QGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASP----WSHISA- 778
Query: 239 SNYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
A++LI+ ++ + +KR+ K L + QE
Sbjct: 779 --------------------------GAIDLINNLLQVKMRKRYSVDKSLSHPWLQE 809
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 110 bits (274), Expect = 3e-24
Identities = 87/296 (29%), Positives = 136/296 (45%), Gaps = 37/296 (12%)
Query: 5 STVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQEL 64
STV ++ G G + +VY G + TGR +A+K I +F + EV LQ L
Sbjct: 571 STVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNL 630
Query: 65 KHVNVIELVDVFMANDNLNLVLEFLPAD-LEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H ++ L +F + + +V+E L D LE+I+ K + L + +
Sbjct: 631 HHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNL 690
Query: 124 HRNFILHRDLKPNNLLLA---PDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLF 180
H I+H DLKP N+LLA P Q+K+ DFG AR++ + S V T Y APE+L
Sbjct: 691 HFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGE-KSFRRSVVGTPAYLAPEVL- 748
Query: 181 GAKHYTSAVDIWSVGV-IFAELMLRIPYLPGKDDVDQINVTFRALGTPTDADWPEVSSFS 239
+K Y ++D+WSVGV I+ L P+ +D DQI
Sbjct: 749 RSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQ--------------------- 787
Query: 240 NYNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRWDAVKCLQSQYFQE 295
N +YPP E+ + A++LI+ ++ + +KR+ K L + Q+
Sbjct: 788 --NAAFMYPPNPWREI-------SGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQD 834
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 109 bits (273), Expect = 4e-24
Identities = 61/194 (31%), Positives = 108/194 (55%), Gaps = 6/194 (3%)
Query: 10 YTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVNV 69
YTK +K G+G VY + STG +A+K++ SQ + E+ ++E KH NV
Sbjct: 430 YTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQ--QPKKELIINEILVMRENKHPNV 487
Query: 70 IELVDVFMANDNLNLVLEFLPA-DLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFI 128
+ +D ++ ++ L +V+E+LP L ++ +T + I + L+ + H N +
Sbjct: 488 VNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCM--DEGQIAAVCREVLQALEFLHANQV 545
Query: 129 LHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSA 188
+HRD+K +N+LL DG +K+ DFG ++ Q T+ V T ++ APE++ K Y
Sbjct: 546 IHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVV-TRKQYGPK 604
Query: 189 VDIWSVGVIFAELM 202
VD+WS+G++ E++
Sbjct: 605 VDLWSLGIMAIEMV 618
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 109 bits (272), Expect = 6e-24
Identities = 69/203 (33%), Positives = 112/203 (54%), Gaps = 7/203 (3%)
Query: 3 LKSTVDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKD-GLDMSALREVKFL 61
L S + +Y K G G++A V L +TG +A+K + S+ K+ G+++ RE+K L
Sbjct: 12 LVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKIL 71
Query: 62 QELKHVNVIELVDVFMANDNLNLVLEFLPAD--LEIIIKDTSIMFSPADIKSWILMTLRG 119
+ L H ++I +V +++ +V+E++ + + I++ + A + + G
Sbjct: 72 RFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEA--RHLFQQIISG 129
Query: 120 VHHCHRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELL 179
V +CHRN I+HRDLKP N+LL +KI DFGL+ +M + TS + Y APE++
Sbjct: 130 VEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTS-CGSPNYAAPEVI 188
Query: 180 FGAKHYTSAVDIWSVGVIFAELM 202
G K Y VDIWS GVI L+
Sbjct: 189 SG-KPYGPDVDIWSCGVILYALL 210
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 109 bits (272), Expect = 6e-24
Identities = 67/206 (32%), Positives = 105/206 (50%), Gaps = 6/206 (2%)
Query: 10 YTKEKKAGEGTYAVVYLGTK-KSTGRSIAVKEIKTSQFKDGLDMSALREVKFLQELKHVN 68
Y K G G +A VY ++ G S+A+K ++ + KDGL RE+ ++ L+H +
Sbjct: 28 YDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKREISVMRRLRHPH 87
Query: 69 VIELVDVFMANDNLNLVLEFLPADLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFI 128
++ L +V + V+E E+ + TS F+ + + + + V +CH +
Sbjct: 88 IVLLSEVLATKTKIYFVMELAKGG-ELFSRVTSNRFTESLSRKYFRQLISAVRYCHARGV 146
Query: 129 LHRDLKPNNLLLAPDGQLKIADFGLARL--MASPQEILTSNVVTRWYRAPELLFGAKHYT 186
HRDLKP NLLL + LK++DFGL+ + P +L + T Y APELL +
Sbjct: 147 FHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDG 206
Query: 187 SAVDIWSVGVIFAELMLRIPYLPGKD 212
S DIWS GV+ +L YLP +D
Sbjct: 207 SKADIWSCGVVL--FLLNAGYLPFRD 230
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 109 bits (272), Expect = 6e-24
Identities = 63/191 (32%), Positives = 105/191 (53%), Gaps = 4/191 (2%)
Query: 14 KKAGEGTYAVVYLGTKKSTGRSIAVKEIKTSQFKDGLDMSALR-EVKFLQELKHVNVIEL 72
KK G+GTY V LG K TG+ +A+K IK + + D+ +R EV+ + + H N+I +
Sbjct: 86 KKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHI 145
Query: 73 VDVFMANDNLNLVLEFLPA-DLEIIIKDTSIMFSPADIKSWILMTLRGVHHCHRNFILHR 131
+VF + + LV+EF +L + + ++ + + + V++CH++ I HR
Sbjct: 146 YEVFENREKMVLVMEFAAGGELYDYLSERKVL-TEEEARRIFRQVATAVYYCHKHKICHR 204
Query: 132 DLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAKHYTSAVDI 191
DLK N+LL G KIADFGL+ + Q +L + + Y +PE++ G + VD
Sbjct: 205 DLKLENILLDEKGNAKIADFGLSNVF-DDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDC 263
Query: 192 WSVGVIFAELM 202
WS+GV+ L+
Sbjct: 264 WSLGVLLYTLV 274
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 108 bits (271), Expect = 8e-24
Identities = 68/206 (33%), Positives = 109/206 (52%), Gaps = 7/206 (3%)
Query: 7 VDDYTKEKKAGEGTYAVVYLGTKKSTGRSIAVKEI-KTSQFKDGLDMSALREVKFLQELK 65
V Y + GEGT+A V TG ++A+K + K++ K+ + RE+ ++ ++
Sbjct: 8 VGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVR 67
Query: 66 HVNVIELVDVFMANDNLNLVLEFLPAD--LEIIIKDTSIMFSPADIKSWILMTLRGVHHC 123
H N++ L +V + + +VLEF+ + I+ + ++ + + + V HC
Sbjct: 68 HPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRL--EESESRKYFQQLVDAVAHC 125
Query: 124 HRNFILHRDLKPNNLLLAPDGQLKIADFGLARLMASPQEILTSNVVTRWYRAPELLFGAK 183
H + HRDLKP NLLL +G LK++DFGL+ L E+L + T Y APE+L G
Sbjct: 126 HCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQG 185
Query: 184 HYTSAVDIWSVGVIFAELMLRIPYLP 209
+ SA DIWS GVI ++ YLP
Sbjct: 186 YDGSAADIWSCGVIL--FVILAGYLP 209
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 107 bits (268), Expect = 2e-23
Identities = 87/314 (27%), Positives = 156/314 (48%), Gaps = 32/314 (10%)
Query: 2 TLKSTVDDYTKEKKAGEGTYAVVYLGT-KKSTGRSIAVKEIKT-SQFKDGLDMSALREVK 59
T + V +Y K + GT YL KK+ A+K++ +++K RE++
Sbjct: 30 TRRMLVKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKS-------RELQ 82
Query: 60 FLQELKHVNVIELVDVFM---ANDNL---NLVLEFLPADLEIIIKD--TSIMFSPAD-IK 110
L+ H N+++L F DN +L +E LP L+I I T+ + P I+
Sbjct: 83 ILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIR 142
Query: 111 SWILMTLRGVHHCHRNFILHRDLKPNNLLLAPD-GQLKIADFGLARLMASPQEILTSNVV 169
+ RG+ + H + HRD+KP+N+L+ P+ G LKI DFG A+ + Q + S +
Sbjct: 143 LYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSI-SYIC 201
Query: 170 TRWYRAPELLFGAKHYTSAVDIWSVGVIFAELMLRIPYLPGKDDVDQINVTFRALGTPTD 229
+R+YRAPEL+ G YT+ +DIW +G + E+++ G++ + Q+ + LG P
Sbjct: 202 SRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPD- 260
Query: 230 ADWPEVSSFSN-------YNKIQIYPPPSREELRRRFIAATENALELISGMMIMNPKKRW 282
FSN ++K ++ S++ + F + + ++L+ +++ P++R
Sbjct: 261 ---KRFIFFSNPAYDGPLFSK-PLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRL 316
Query: 283 DAVKCLQSQYFQEL 296
+ L Q+F EL
Sbjct: 317 SPRRILAHQFFNEL 330
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,737,669
Number of Sequences: 60738
Number of extensions: 781560
Number of successful extensions: 7183
Number of sequences better than 1.0e-05: 1622
Number of HSP's better than 0.0 without gapping: 373
Number of HSP's successfully gapped in prelim test: 1249
Number of HSP's that attempted gapping in prelim test: 3712
Number of HSP's gapped (non-prelim): 1841
length of query: 310
length of database: 30,389,216
effective HSP length: 106
effective length of query: 204
effective length of database: 23,950,988
effective search space: 4886001552
effective search space used: 4886001552
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)