ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3987 good R KOG0370 General function prediction only Multifunctional pyrimidine synthesis protein CAD (includes carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3987 1370741 1377424 2228
(2228 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein... 3516 0.0
SPAC22G7.06c [R] KOG0370 Multifunctional pyrimidine synthesis pr... 2763 0.0
Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 2020 0.0
7293258 [R] KOG0370 Multifunctional pyrimidine synthesis protein... 1942 0.0
CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein... 1849 0.0
Hs21361331 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 1430 0.0
HsM4503019 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 1409 0.0
SPBC215.08c [R] KOG0370 Multifunctional pyrimidine synthesis pro... 1095 0.0
YJR109c [R] KOG0370 Multifunctional pyrimidine synthesis protein... 1055 0.0
YOR303w [R] KOG0370 Multifunctional pyrimidine synthesis protein... 343 2e-93
SPBC56F2.09c [R] KOG0370 Multifunctional pyrimidine synthesis pr... 334 1e-90
At1g29900 [R] KOG0370 Multifunctional pyrimidine synthesis prote... 287 1e-76
At3g20330 [R] KOG0370 Multifunctional pyrimidine synthesis prote... 241 1e-62
At3g27740 [R] KOG0370 Multifunctional pyrimidine synthesis prote... 234 2e-60
At1g75330 [E] KOG1504 Ornithine carbamoyltransferase OTC/ARG3 86 7e-16
Hs9257234 [E] KOG1504 Ornithine carbamoyltransferase OTC/ARG3 78 1e-13
SPAC4G9.10 [E] KOG1504 Ornithine carbamoyltransferase OTC/ARG3 76 7e-13
YBR208c_2 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 66 6e-10
Hs4557833 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 59 1e-07
SPBC17G9.11c [C] KOG0369 Pyruvate carboxylase 56 8e-07
Hs4505627 [C] KOG0369 Pyruvate carboxylase 54 2e-06
At1g03090 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 54 2e-06
YMR207c [I] KOG0368 Acetyl-CoA carboxylase 53 5e-06
7303838 [C] KOG0369 Pyruvate carboxylase 53 5e-06
>YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2214
Score = 3516 bits (9118), Expect = 0.0
Identities = 1750/2219 (78%), Positives = 1969/2219 (87%), Gaps = 22/2219 (0%)
Query: 14 MESTGDRMITLELKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVIT 73
MESTGDR++TLELKDGT LQGYSFGAE + AGELVFQTGMVGYPES+TDPSYEGQILVIT
Sbjct: 14 MESTGDRLVTLELKDGTVLQGYSFGAEKSVAGELVFQTGMVGYPESVTDPSYEGQILVIT 73
Query: 74 FPLVGNYGVPDRKLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKE 133
+PLVGNYGVPD L DE VE LPRYFESNRIH+AGLVI+HYT+EYSH+L +SSLG WL+
Sbjct: 74 YPLVGNYGVPDMHLRDELVEELPRYFESNRIHIAGLVISHYTDEYSHYLRKSSLGKWLQN 133
Query: 134 SNVPAVYGIDSRSLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVD 193
+PAVYG+D+RSLTKHLR+AGSMLGR +L+K G+ + S+ W S F+ PEWVDPNV
Sbjct: 134 EGIPAVYGVDTRSLTKHLRDAGSMLGRLSLEKSGSDRTISRSSSWRSAFDVPEWVDPNVQ 193
Query: 194 NLVAKVSLKAPKLFVP--NHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLV 251
NLV+KVS+ PKL+VP ++ I+L GPDGK LRI+A+DVGMKYNQIRCF+KRGVEL V
Sbjct: 194 NLVSKVSINEPKLYVPPADNKHIELQTGPDGKVLRILAIDVGMKYNQIRCFIKRGVELKV 253
Query: 252 VPWDYDFTTEEYDGLFISNGPGNPAILQEVSDRLTKVLDAKKTPVFGICLGHQLLARASG 311
VPW+YDFT E+YDGLFISNGPG+P++L ++S RL+ VL+AKKTPVFGICLGHQL+ARA+G
Sbjct: 254 VPWNYDFTKEDYDGLFISNGPGDPSVLDDLSQRLSNVLEAKKTPVFGICLGHQLIARAAG 313
Query: 312 ASTLKMKFGNRGHNIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGI 371
ASTLK+KFGNRGHNIPCTST+SGRCYITSQNHGFAVD +LT+GWK LF NAND SNEGI
Sbjct: 314 ASTLKLKFGNRGHNIPCTSTISGRCYITSQNHGFAVDVDTLTSGWKPLFVNANDDSNEGI 373
Query: 372 YHSELPYFSVQFHPESTPGPRDTEFLFDVFIQSVLDFKQTGVLKQVEFPGGNIEENLAAH 431
YHSELPYFSVQFHPESTPGPRDTEFLFDVFIQ+V +FK T VLK + FPGG +E+N+ AH
Sbjct: 374 YHSELPYFSVQFHPESTPGPRDTEFLFDVFIQAVKEFKYTQVLKPIAFPGGLLEDNVKAH 433
Query: 432 PREDXXXXXXXXXXXXXIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLAD 491
PR + IGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLAD
Sbjct: 434 PRIEAKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLAD 493
Query: 492 KVYFLPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIEMKDEFETLGVKVLGTPIDTVI 551
KVYF+PVTAEFVRKVILHERPDAIYVTFGGQTALSVGI MKDEFE LGVKVLGTPIDT+I
Sbjct: 494 KVYFVPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIAMKDEFEALGVKVLGTPIDTII 553
Query: 552 TTEDRELFANAMDEINXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASN 611
TTEDRELF+NA+DEIN +IGFPVIVRAAYALGGLGSGFA+N
Sbjct: 554 TTEDRELFSNAIDEINEKCAKSQAANSVDEALAAVKEIGFPVIVRAAYALGGLGSGFANN 613
Query: 612 EKELVDLCNVAFASSPQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGD 671
EKELVDLCNVAF+SSPQVLVE+SMKGWKE+EYEVVRDAFDNCITVCNMENFDPLGIHTGD
Sbjct: 614 EKELVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCNMENFDPLGIHTGD 673
Query: 672 SIVIAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXX 731
SIV+APSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNP SK+YCIIEVN
Sbjct: 674 SIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKDYCIIEVNARLSRS 733
Query: 732 XXXXXXXTGYPLAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKFT 791
TGYPLAYTAAKLGLNIPL EVKNSVT+STCACFEPSLDYCVVKMPRWDLKKFT
Sbjct: 734 SALASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYCVVKMPRWDLKKFT 793
Query: 792 RVSTLLSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYSNIGFSETDDELDIDYELSNPSDM 851
RVST LSSSMKSVGEVMSIGRTFEEAIQKAIRSTEY+N+GF+ETD ++DIDYEL+NP+DM
Sbjct: 794 RVSTELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLDIDIDYELNNPTDM 853
Query: 852 RIFAIANAFAKFGYSIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALVLKQA 911
R+FAIANAFAK GYS+D+VWE T IDKWFLNKL+ L++F++KISS+G+KE LP+LVL+QA
Sbjct: 854 RVFAIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFGTKEELPSLVLRQA 913
Query: 912 KQLGFEDRQIAKFLNSNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYNAAAH 971
KQLGF+DRQIA+FL+SNEVAIRRLRKEYGI PFVKQIDTVAAEFPA+TNYLY+TYNA +H
Sbjct: 914 KQLGFDDRQIARFLDSNEVAIRRLRKEYGITPFVKQIDTVAAEFPAYTNYLYMTYNADSH 973
Query: 972 DLDFNDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEA 1031
DL F+DHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLR NN KTIMVNYNPETVSTDYDEA
Sbjct: 974 DLSFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVNYNPETVSTDYDEA 1033
Query: 1032 DRLYFETINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMIDSAE 1091
DRLYFETINLER++DIYE+E+S+GVVVSMGGQTSNNIAM+LHRENVKILGTSP+MIDSAE
Sbjct: 1034 DRLYFETINLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVKILGTSPDMIDSAE 1093
Query: 1092 NRYKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDD 1151
NRYKFSRMLDQI VDQPAWKELTSMDEAE FAEKV YPVLVRPSYVLSGAAMNTVYSK+D
Sbjct: 1094 NRYKFSRMLDQIGVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVLSGAAMNTVYSKND 1153
Query: 1152 LESYLNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDAT 1211
LESYLNQAVEVSR+YPVVITKYIENAKEIEMDAVA +GEL+MHVVSEHVENAGVHSGDAT
Sbjct: 1154 LESYLNQAVEVSRDYPVVITKYIENAKEIEMDAVARNGELVMHVVSEHVENAGVHSGDAT 1213
Query: 1212 LIVPPQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNNEIKVIECNVRASRSFPFI 1271
LIVPPQDL PETV RIV ATAKIG+AL+ITGPYNIQFIAK+NEIKVIECNVRASRSFPFI
Sbjct: 1214 LIVPPQDLAPETVDRIVVATAKIGKALKITGPYNIQFIAKDNEIKVIECNVRASRSFPFI 1273
Query: 1272 SKVVGVNLIEMATKAIMGIPVTPYPVEKLPDDYVAIKVPQFSFPRLAGADPVLGVEMAST 1331
SKVVGVNLIE+ATKAIMG+P+TPYPVEKLPDDYVA+KVPQFSFPRLAGADPVLGVEMAST
Sbjct: 1274 SKVVGVNLIELATKAIMGLPLTPYPVEKLPDDYVAVKVPQFSFPRLAGADPVLGVEMAST 1333
Query: 1332 GEVAAFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLPGVKKLYNMGYKLFAT 1391
GEVA FGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELL V+KLYNMGYKLFAT
Sbjct: 1334 GEVATFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLSSVQKLYNMGYKLFAT 1393
Query: 1392 AGTADFISEHGIPVQYLEVLN-EEDDEKSEYSLTQHLANNKIDLYINLPSANRFRRPASY 1450
+GTADF+SEHGI VQYLEVLN ++DD+KSEYSLTQHLANN+IDLYINLPSANRFRRPASY
Sbjct: 1394 SGTADFLSEHGIAVQYLEVLNKDDDDQKSEYSLTQHLANNEIDLYINLPSANRFRRPASY 1453
Query: 1451 VSKGYRTRRMAVDFSVPLVTNVKCAKLLIEALSRNMSLDVSERDAQTSHRTVTIPGLINI 1510
VSKGY+TRR+AVD+SVPLVTNVKCAKLLIEA+SRN++LDVSERDAQTSHRT+T+PGLINI
Sbjct: 1454 VSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISRNITLDVSERDAQTSHRTITLPGLINI 1513
Query: 1511 SAYVPNISNVLLGPAELKEVTRLSVESGFTYSQIMPKSSSGPVITDAASLKVANSVVKDS 1570
+ YVPN S+V+ GPAELKE TRL +ESGFTY Q+MP+S SGPVITD ASLK ANSV +DS
Sbjct: 1514 ATYVPNASHVIKGPAELKETTRLFLESGFTYCQLMPRSISGPVITDVASLKAANSVSQDS 1573
Query: 1571 AYTNFGFTVAATPNNIDTVSAVANEATSLFLPYRELSNNVPAVSEHLKHWPLDKPVIAEA 1630
+YT+F FT+A T +N +V+ A++ T+LFLP REL N + AV+E L WP +K VIAEA
Sbjct: 1574 SYTDFSFTIAGTAHNAHSVTQSASKVTALFLPLRELKNKITAVAELLNQWPTEKQVIAEA 1633
Query: 1631 KTSDLASVILLASLQNRSIHITAVSNKEDLSLVMAVKEKQSNVTCDVNIHSLFVSQDDYP 1690
KT+DLASV+LL SLQNRSIHIT VSNKEDL+L+M VK K VTCDVNI+SLF++QDDYP
Sbjct: 1634 KTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNIYSLFIAQDDYP 1693
Query: 1691 EAKFLPTKEDQEFFWSNLESIDAFSIGSLPTALAAVTGNEIVTGLGIKEALPLLLSAVND 1750
EA FLPTKEDQEFFW+NL+SIDAFS+G+LP ALA VTGN++ G+GIK++LPLLL+AV +
Sbjct: 1694 EAVFLPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGMGIKDSLPLLLAAVEE 1753
Query: 1751 GRLTIDDIVERLHINPAKIFSIPEQNSAVEVDLDFTFRHTKRWSPYQKGGLTGGIQRVLI 1810
G+LTIDDIV RLH NPAKIF+IP Q+S VE+DLD++FR KRWSP+ K + GGI+RV+
Sbjct: 1754 GKLTIDDIVLRLHDNPAKIFNIPTQDSVVEIDLDYSFRRNKRWSPFNK-DMNGGIERVVY 1812
Query: 1811 NEETIVLSGDLVATEAKGQPIL-PSKFTPTTPAVAKETPLAAVGTPILGAISTSRKRFSF 1869
N ET+VLSG+LV+ AKG+ I+ PS + T A + T ++++RFS
Sbjct: 1813 NGETLVLSGELVSPGAKGKCIVNPSPASITASAELQST--------------SAKRRFSI 1858
Query: 1870 SNERRLSINSMDGDDEEAILDQPLEQRLMSSRPPKELSAPSVLINLIRTKNPFLRRNILS 1929
+ E +++D E+AI +QPLEQ+LMSSRPP+EL AP + NLIR+ NPF R+ILS
Sbjct: 1859 TEE--AIADNLDA-AEDAIPEQPLEQKLMSSRPPRELVAPGAIQNLIRSNNPFRGRHILS 1915
Query: 1930 VNQFKRSDFHALFAVAQELRAGVEREGVLDVMKSRVLTTMFYEPSTRTSSSFIAAMERLG 1989
+ QFKRSDFH LFAVAQELRA V REGVLD+MK V+TT+F+EPSTRT SSFIAAMERLG
Sbjct: 1916 IKQFKRSDFHVLFAVAQELRAAVAREGVLDLMKGHVITTIFFEPSTRTCSSFIAAMERLG 1975
Query: 1990 GRTVNINTSASSVKKGETLQDTIRTLACYSDAIVLRHPDEMSAHIAAKYSPVPIINGGNG 2049
GR VN+N SSVKKGETLQDTIRTLACYSDAIV+RH +EMS HIAAKYSPVPIINGGNG
Sbjct: 1976 GRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVPIINGGNG 2035
Query: 2050 SREHPTQAFLDLFTIREELGTVNGITVTFMGDLKFGRPVHSLCRLLQHYQVRINLIAPKE 2109
SREHPTQAFLDLFTIREE+GTVNGITVTFMGDLK GR VHSLCRLL HYQVRINL++P E
Sbjct: 2036 SREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRINLVSPPE 2095
Query: 2110 LRLPNALRKELQDSGLLGIESETLTPEIISKSDVLYCTRVQQERFETEEDYLKLKDTYIV 2169
LRLP LR+EL+ +GLLG+ES LTP IISK+DVLYCTRVQ+ERF + E+Y +LKDTYIV
Sbjct: 2096 LRLPEGLREELRKAGLLGVESIELTPHIISKTDVLYCTRVQEERFNSPEEYARLKDTYIV 2155
Query: 2170 DNKILSHAKQQMVVMHPLPRVNEIREEVDYDHRAAYFRQMRYGLFVRMALLAMVMGVEL 2228
DNKIL+HAK+ M +MHPLPRVNEI+EEVDYDHRAAYFRQM+YGLFVRMALLAMVMGV++
Sbjct: 2156 DNKILAHAKENMAIMHPLPRVNEIKEEVDYDHRAAYFRQMKYGLFVRMALLAMVMGVDM 2214
>SPAC22G7.06c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2244
Score = 2763 bits (7162), Expect = 0.0
Identities = 1397/2220 (62%), Positives = 1713/2220 (76%), Gaps = 52/2220 (2%)
Query: 20 RMITLELKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVGN 79
+++ LEL+D + LQGYSFGA+ + +GELVFQTGMVGYPES+TDPSY GQILV TFP VGN
Sbjct: 57 KLMALELEDKSVLQGYSFGADHSVSGELVFQTGMVGYPESLTDPSYRGQILVFTFPTVGN 116
Query: 80 YGVPDRKLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKESNVPAV 139
YGVPDR+++DE + GLP+YFESN+IHVA ++I+ Y++ YSH+LA SSLG WLKE +P +
Sbjct: 117 YGVPDRRILDE-ISGLPKYFESNQIHVAAIIISSYSQNYSHFLAHSSLGEWLKEQGIPGI 175
Query: 140 YGIDSRSLTKHLREAGSMLGRFALQKPGTSFEDAN----SAEWMSYFETPEWVDPNVDNL 195
+GID+R+LTK +R+ GSMLGR +QK + ++ +W + FE W +PN +NL
Sbjct: 176 FGIDTRALTKKIRDQGSMLGRLLIQKDESPINPSSITGLGKDWSTAFEDIPWKNPNTENL 235
Query: 196 VAKVSLKAPKLFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWD 255
++VS+K PKL+ P HP ++ DGK +RI+ +DVGMKYNQIRCF+ RGVELLVVPWD
Sbjct: 236 TSQVSIKEPKLYEP-HPTT-AIKKADGKIIRILVIDVGMKYNQIRCFLNRGVELLVVPWD 293
Query: 256 YDFTTEEYDGLFISNGPGNPAILQEVSDRLTKVLDAKKTPVFGICLGHQLLARASGASTL 315
YDFT E YDGLFISNGPG+P+++ V DR+ +VL++K PVFGIC GHQ++ARA+GAST
Sbjct: 294 YDFTKETYDGLFISNGPGDPSLMDLVVDRVKRVLESKTVPVFGICFGHQIMARAAGASTT 353
Query: 316 KMKFGNRGHNIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHSE 375
KMKFGNRGHNIPCT +SGRCYITSQNHG+AVD +SL+NGWK LF NANDGSNEGIY++E
Sbjct: 354 KMKFGNRGHNIPCTCMISGRCYITSQNHGYAVDASSLSNGWKELFVNANDGSNEGIYNTE 413
Query: 376 LPYFSVQFHPESTPGPRDTEFLFDVFIQSVLDFKQTGVLKQVEFPGGNIEENLAAHPRED 435
P+FSVQFHPESTPGPRDTEFLFDVFI V L+ + PGG IEEN + HP D
Sbjct: 414 YPFFSVQFHPESTPGPRDTEFLFDVFIDVVKRSADAKSLQPFKLPGGTIEENRSRHPLVD 473
Query: 436 XXXXXXXXXXXXXIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYF 495
IGQAGEFDYSGSQAIKAL+EEGIYTILINPNIATIQTSKGLADKVYF
Sbjct: 474 AKRVLILGSGGLSIGQAGEFDYSGSQAIKALREEGIYTILINPNIATIQTSKGLADKVYF 533
Query: 496 LPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIEMKDEFETLGVKVLGTPIDTVITTED 555
LPV A+FVRKVI ERPD+IYVTFGGQTAL+VGIE+KDEFE LGVKVLGTPIDT+ITTED
Sbjct: 534 LPVNADFVRKVIKQERPDSIYVTFGGQTALNVGIELKDEFEQLGVKVLGTPIDTIITTED 593
Query: 556 RELFANAMDEINXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASNEKEL 615
RELFA AMDEIN DI FPVIVRAAYALGGLGSGFA NE EL
Sbjct: 594 RELFARAMDEINEKCAKSASASSIEEAIKVSKDISFPVIVRAAYALGGLGSGFADNEAEL 653
Query: 616 VDLCNVAFASSPQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVI 675
+DLC +AFA+SPQVL+ERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIV+
Sbjct: 654 IDLCTLAFATSPQVLIERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVV 713
Query: 676 APSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXXXXXX 735
APSQTL+DEDYNMLRTTAVNVIRHLGVVGECNIQYALNP +KEYCIIEVN
Sbjct: 714 APSQTLTDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPFTKEYCIIEVNARLSRSSALA 773
Query: 736 XXXTGYPLAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKFTRVST 795
TGYPLA+TAAKLGLNIPL EVKNSVT+ TCACFEPSLDY VVK+PRWDLKKFTRVST
Sbjct: 774 SKATGYPLAFTAAKLGLNIPLNEVKNSVTKVTCACFEPSLDYVVVKIPRWDLKKFTRVST 833
Query: 796 LLSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYSNIGFSETDDELDIDYELSNPSDMRIFA 855
LSS+MKSVGEVMSIGRTFEEAIQKAIR+ +YSN GF+ D + ID EL PSD R+FA
Sbjct: 834 QLSSAMKSVGEVMSIGRTFEEAIQKAIRAIDYSNTGFNVKDALMSIDTELQTPSDQRLFA 893
Query: 856 IANAFAKFGYSIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALVLKQAKQLG 915
IANA A GYS+D++WE T IDKWFL KL LI+ S IS + +LP +LK AKQLG
Sbjct: 894 IANAMAS-GYSVDRIWELTRIDKWFLEKLMGLIRTSQLISKH-DISSLPISLLKTAKQLG 951
Query: 916 FEDRQIAKFLNSNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYNAAAHDLDF 975
F D QIA F+NS E+A+RR+R E GI PFVKQIDTVAAEFPA TNYLY TYNA HD+ F
Sbjct: 952 FADVQIAAFMNSTELAVRRIRTEAGIRPFVKQIDTVAAEFPAFTNYLYTTYNAVEHDIHF 1011
Query: 976 NDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLY 1035
ND GVMVLGSGVYRIGSSVEFDWCAV AVRTLR KTIMVNYNPETVSTDYDEADRLY
Sbjct: 1012 NDKGVMVLGSGVYRIGSSVEFDWCAVRAVRTLRDRGVKTIMVNYNPETVSTDYDEADRLY 1071
Query: 1036 FETINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMIDSAENRYK 1095
FE I LE ++DIYE ESS+G++++MGGQT+NNIA+ LHRENVKILGTSPEMID AENR+K
Sbjct: 1072 FENIGLETVLDIYEQESSSGIIIAMGGQTANNIALPLHRENVKILGTSPEMIDGAENRFK 1131
Query: 1096 FSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLESY 1155
FSRMLD I VDQP WKELTS DEA+ F + V YPVLVRPSYVLSGAAMNTVYS+ DL SY
Sbjct: 1132 FSRMLDDIGVDQPKWKELTSFDEADKFCDTVGYPVLVRPSYVLSGAAMNTVYSQSDLHSY 1191
Query: 1156 LNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLIVP 1215
L QAV +++++PVVI+KYIENAKEIE+DAVA +G+++MHV+SEHVENAGVHSGDATL++P
Sbjct: 1192 LQQAVAINKDHPVVISKYIENAKEIELDAVAREGKMVMHVISEHVENAGVHSGDATLVLP 1251
Query: 1216 PQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNNEIKVIECNVRASRSFPFISKVV 1275
PQDL P T+ RIV+A AKIG AL ITGPYNIQFIAK+NEIKVIECNVRASRSFPF+SKV+
Sbjct: 1252 PQDLAPTTIERIVDAAAKIGEALNITGPYNIQFIAKDNEIKVIECNVRASRSFPFVSKVI 1311
Query: 1276 GVNLIEMATKAIMGIPVTPYPVEKLPDDYVAIKVPQFSFPRLAGADPVLGVEMASTGEVA 1335
GV++I MAT IMG P+ PYP LP DYVA+KVPQFSF RL+GADPVLGVEMASTGEVA
Sbjct: 1312 GVDMISMATDVIMGNPIQPYPDVDLPRDYVAVKVPQFSFSRLSGADPVLGVEMASTGEVA 1371
Query: 1336 AFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLPGVKKLYNMGYKLFATAGTA 1395
FGH+K+EAYLK++++TGF+LPKKNIL+SIGSYKEK ELLP VKKLY Y +FATAGT+
Sbjct: 1372 CFGHNKFEAYLKAMISTGFRLPKKNILISIGSYKEKAELLPYVKKLYENNYNIFATAGTS 1431
Query: 1396 DFISEHGIPVQYLEVLNEEDDEKSEYSLTQHLANNKIDLYINLPSANRFRRPASYVSKGY 1455
D+ E G+P +YL L E + +EYSL+ HLANN ID+YINLPS NR+RRPA+Y+S GY
Sbjct: 1432 DYFMESGVPCKYLADLPAE-EANNEYSLSAHLANNMIDMYINLPSNNRYRRPANYISSGY 1490
Query: 1456 RTRRMAVDFSVPLVTNVKCAKLLIEALSRNMSLDVSERDAQTSHRTVTIPGLINISAYVP 1515
++RR+A+D+SVPLVTNVKCAKL+IEA+ RN+ +S D Q+S +T +PGLINISA++P
Sbjct: 1491 KSRRLAIDYSVPLVTNVKCAKLMIEAICRNLDFSLSTVDFQSSFQTANLPGLINISAFLP 1550
Query: 1516 NISNVLLGPAELKEVTRLSVESGFTYSQIMPKSSSGPVITDAASLKVANSVVKDSAYTNF 1575
++ + + T+ + SGFT ++ +P S+S + D SL + D A+ ++
Sbjct: 1551 EFTS-----EAVSDYTKECIASGFTMARFLPFSTSS-TLADKDSLSAVKKLALDHAHCDY 1604
Query: 1576 GFTVAATPNNIDTVSAVANEATSLFLPYRELS---NNVPAVSEHLKHWPLDKPVIAEAKT 1632
F+V A+ N T+S + +E+ LF + + ++V AV+ H WP + V+ +AK+
Sbjct: 1605 NFSVIASSTNEVTISELTSESGCLFFHFEKDDSGIDHVTAVASHFNVWPDTQTVMTDAKS 1664
Query: 1633 SDLASVILLASLQNRSIHITAVSNKEDLSLVMAVKEKQSNVTCDVNIHSLFVSQDDYPEA 1692
+ LAS++LLASL NR IHIT VS+K+DL+L++ K++ VT DV+++SLF++Q+DYP A
Sbjct: 1665 TTLASLLLLASLHNRRIHITNVSSKDDLNLIVLAKQRSLPVTFDVSVYSLFLNQNDYPGA 1724
Query: 1693 KFLPTKEDQEFFWSNLESIDAFSIGSLPTALAAVTGNEIVTGLGIKEALPLLLSAVNDGR 1752
FLPT +DQ W+ L ID FSIGS+P+ LA GN TG G++EA+PLLL+AVN+GR
Sbjct: 1725 TFLPTADDQVEIWNKLSYIDCFSIGSIPSRLAKFVGNTAFTGFGVREAIPLLLTAVNEGR 1784
Query: 1753 LTIDDIVERLHINPAKIFSIPEQ-NSAVEVDLDFTFR-HTKRWSPYQKGGLTGGIQRVLI 1810
LT+ D+V+R + NP IF + +Q +S V++++D + +K W+P+ L G IQ V
Sbjct: 1785 LTLKDVVDRFYSNPKAIFRLHDQDDSGVQLEVDRSVSWSSKDWTPFNGKKLYGSIQSVQF 1844
Query: 1811 NEETIVLSGDLVATEAKGQPILPSKFTPTTPAVAKETPLAAVGTPILGAISTSRKRFSFS 1870
+ + G+L G+ + + A K + L + G P A + + F +
Sbjct: 1845 DGHDVFFDGELNFEHTYGRDYSSASLADKSKATRKVSALMSPGLP--HAAPSLAEAFGQA 1902
Query: 1871 NERR----LSINSMDGDDEEAILDQPLEQRLMSSRPPKELSAPSVLINLIRTKNPFLRRN 1926
E + +S+N + +P E L+ LI + +PF R++
Sbjct: 1903 PENKAHPDISLNMTP-----------------NFKPSHE------LVQLINS-SPFYRKH 1938
Query: 1927 ILSVNQFKRSDFHALFAVAQELRAGVEREGVLDVMKSRVLTTMFYEPSTRTSSSFIAAME 1986
I+SV+Q RSD H LFA+A ++R VER+GV+D+ ++L TMF+EPSTRTSSSF AAM+
Sbjct: 1939 IISVHQVTRSDLHVLFAIAHQMRIIVERQGVIDLCYGKLLCTMFFEPSTRTSSSFDAAMQ 1998
Query: 1987 RLGGRTVNINTSASSVKKGETLQDTIRTLACYSDAIVLRHPDEMSAHIAAKYSPVPIING 2046
RLGG+ V + SASSV KGE+L DTIRTL CY DAIVLRHP SA IAA +SPVPIING
Sbjct: 1999 RLGGKVVAVTASASSVNKGESLADTIRTLGCYGDAIVLRHPSIESARIAANFSPVPIING 2058
Query: 2047 GNGSREHPTQAFLDLFTIREELGTVNGITVTFMGDLKFGRPVHSLCRLLQHYQVRINLIA 2106
GNGS+EHPTQAFLDL+TIREELG+VNG+T+TF+GDLK+GR VHSL RLL + V ++L++
Sbjct: 2059 GNGSKEHPTQAFLDLYTIREELGSVNGLTITFIGDLKYGRTVHSLARLLAFWHVELHLVS 2118
Query: 2107 PKELRLPNALRKELQDSGLLGIESETLTPEIISKSDVLYCTRVQQERFETEEDYLKLKDT 2166
P++L LP+ ++ +++ +GL IE LT E++++SDVLYCTRVQ+ERF + ++Y KLKD+
Sbjct: 2119 PEQLALPDDVKDDIRANGLNFIEHRELTKEVVAQSDVLYCTRVQKERFASVDEYEKLKDS 2178
Query: 2167 YIVDNKILSHAKQQMVVMHPLPRVNEIREEVDYD-HRAAYFRQMRYGLFVRMALLAMVMG 2225
+IVDN +L+ AK +VMHPLPR EI EEVD+D RAAYFRQMRYGL++RMALLA VMG
Sbjct: 2179 FIVDNSVLASAKSHCIVMHPLPRNREISEEVDFDQRRAAYFRQMRYGLYIRMALLACVMG 2238
>Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2225
Score = 2020 bits (5234), Expect = 0.0
Identities = 1109/2284 (48%), Positives = 1476/2284 (64%), Gaps = 140/2284 (6%)
Query: 21 MITLELKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVGNY 80
M L L+DG+ L+G FGA + AGE+VFQTGMVGYPE++TDPSY+ QILV+T+PL+GNY
Sbjct: 1 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY 60
Query: 81 GVPDRKLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKESNVPAVY 140
G+P + MDE+ GL ++FES+ IHVA LV+ SHW A +L WL++ +P +
Sbjct: 61 GIPPDE-MDEF--GLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQ 117
Query: 141 GIDSRSLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDNLVAKVS 200
G+D+R LTK LRE GS+LG+ N E S ++DPN LV +VS
Sbjct: 118 GVDTRELTKKLREQGSLLGKLV----------QNGTEPSSL----PFLDPNARPLVPEVS 163
Query: 201 LKAPKLFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWDYDFTT 260
+K P++F G RI+A+D G+KYNQIRC +RG E+ VVPWD+ +
Sbjct: 164 IKTPRVF------------NTGGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALDS 211
Query: 261 EEYDGLFISNGPGNPAILQEVSDRLTKVL-DAKKTPVFGICLGHQLLARASGASTLKMKF 319
+EY+GLF+SNGPG+PA V L++VL + PVFGICLGHQLLA A GA T KM++
Sbjct: 212 QEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRY 271
Query: 320 GNRGHNIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHSELPYF 379
GNRGHN PC SGRC++TSQNHGFAV+ SL W LFTNANDGSNEGI H+ LP+F
Sbjct: 272 GNRGHNQPCLLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPFF 331
Query: 380 SVQFHPESTPGPRDTEFLFDVFIQSVLDFKQTGVLKQVEFPGGN-IEENLAAH------- 431
SVQFHPE GP D E LFD+F+++V + PGG + E L
Sbjct: 332 SVQFHPEHQAGPSDMELLFDIFLETVKEATAGN-------PGGQTVRERLTERLCPPGIP 384
Query: 432 --------PREDXXXXXXXXXXXXXIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATI 483
PR+ IGQAGEFDYSGSQAIKALKEE I T+LINPNIAT+
Sbjct: 385 TPGSGLPPPRK----VLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATV 440
Query: 484 QTSKGLADKVYFLPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIEMKDE--FETLGVK 541
QTS+GLADKVYFLP+T +V +VI +ERPD + +TFGGQTAL+ G+E+ GV+
Sbjct: 441 QTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVR 500
Query: 542 VLGTPIDTVITTEDRELFANAMDEINXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYAL 601
VLGTP++T+ TEDR FA M EI +G+PV+VRAA+AL
Sbjct: 501 VLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFAL 560
Query: 602 GGLGSGFASNEKELVDLCNVAFASSPQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMEN 661
GGLGSGFASN +EL L AFA + QVLV++S+KGWKEIEYEVVRDA+ NC+TVCNMEN
Sbjct: 561 GGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMEN 620
Query: 662 FDPLGIHTGDSIVIAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCI 721
DPLGIHTG+SIV+APSQTL+D +Y +LR TA+ V +HLG+VGECN+QYALNP S++Y I
Sbjct: 621 LDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYI 680
Query: 722 IEVNXXXXXXXXXXXXXTGYPLAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVK 781
IEVN TGYPLAY AAKL L IPL E++NSVT T A FEPS+DYCVVK
Sbjct: 681 IEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAA-FEPSVDYCVVK 739
Query: 782 MPRWDLKKFTRVSTLLSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYSNIGFSETDDELDI 841
+PRWDL KF RVST + S MKSVGEVM IGR+FEEA QKA+R + + +GF T +
Sbjct: 740 IPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVS- 798
Query: 842 DYELSNPSDMRIFAIANAFAKFGYSIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKE 901
D EL P+D RIF +A A GYS+D+++E T ID+WFL+++ +I + + + +
Sbjct: 799 DMELETPTDKRIFVVAAALWA-GYSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQP 857
Query: 902 NLPALVLKQAKQLGFEDRQIAKFLNSNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNY 961
LP +L+QAK LGF D+QIA + S E+A+R+LR+E GI P VKQIDTVAAE+PA TNY
Sbjct: 858 -LPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNY 916
Query: 962 LYLTYNAAAHDLDFNDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNP 1021
LYLTY HDL F V+VLGSGVYRIGSSVEFDWCAV ++ LRK +KTIMVNYNP
Sbjct: 917 LYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNP 976
Query: 1022 ETVSTDYDEADRLYFETINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILG 1081
ETVSTDYD DRLYF+ I+ E +MDIYELE+ GV++SMGGQ NN+AM+LHR+ ++LG
Sbjct: 977 ETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLG 1036
Query: 1082 TSPEMIDSAENRYKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGA 1141
TSPE IDSAENR+KFSR+LD I + QP W+EL+ ++ A F + V YP +VRPSYVLSGA
Sbjct: 1037 TSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGA 1096
Query: 1142 AMNTVYSKDDLESYLNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVE 1201
AMN Y+ DLE +L+ A VS+E+PVVI+K+I+ AKEI++DAVA DG + +SEHVE
Sbjct: 1097 AMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVE 1156
Query: 1202 NAGVHSGDATLIVPPQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNNEIKVIECN 1261
NAGVHSGDATL+ PPQD+ +T+ RI +G+ LQ+TGP+N+Q IAK++++KVIECN
Sbjct: 1157 NAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECN 1216
Query: 1262 VRASRSFPFISKVVGVNLIEMATKAIMGIPVTPYPVEKLPDDYVAIKVPQFSFPRLAGAD 1321
VR SRSFPF+SK +GV+L+ +AT+ IMG V P + V +KVPQFSF RLAGAD
Sbjct: 1217 VRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGL-MTGSGVVGVKVPQFSFSRLAGAD 1275
Query: 1322 PVLGVEMASTGEVAAFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLPGVKKL 1381
VLGVEM STGEVA FG S+ EAYLK++L+TGFK+PKKNILL+IGSYK K ELLP V+ L
Sbjct: 1276 VVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLL 1335
Query: 1382 YNMGYKLFATAGTADFISEHGIPVQYLEVLNEE--DDE-KSEYSLTQHLANNKIDLYINL 1438
++GY L+A+ GTADF +EHG+ V ++ EE D E + S+ + LA +L INL
Sbjct: 1336 ESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFELVINL 1395
Query: 1439 PSANR-FRRPASYVSKGYRTRRMAVDFSVPLVTNVKCAKLLIEALSR-----NMSLDVSE 1492
RR +S+V+KGYRTRR+A DFSVPL+ ++KC KL +EAL + + + V
Sbjct: 1396 SMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHV-- 1453
Query: 1493 RDAQTSHRTVTIPGLINISAYVPNISNVLLGPAELKEVTRLSVESGFTYSQIMPKSSSGP 1552
D TS + V +PGLI++ ++ + T ++ G T MP ++ P
Sbjct: 1454 -DCMTSQKLVRLPGLIDVHVHLREPGGT--HKEDFASGTAAALAGGITMVCAMP--NTRP 1508
Query: 1553 VITDAASLKVANSVVKDSAYTNFGFTVAATPNNIDTVSAVANEATSLFLPYRELSNNVPA 1612
I DA +L +A + + A +F + A+ N T+ VA A L L E + +
Sbjct: 1509 PIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETFSELRL 1568
Query: 1613 VS-----EHLKHWPLDKPVIAEAKTSDLASVILLASLQNRSIHITAVSNKEDLSLVMAVK 1667
S EH + WP P++A A+ +A+V+++A L RS+HI V+ KE++ L+ A K
Sbjct: 1569 DSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILLIKAAK 1628
Query: 1668 EKQSNVTCDVNIHSLFVSQDDY-----------PEAKFLPTKEDQEFFWSNLESIDAFSI 1716
+ VTC+V H LF+S DD PE L +++D E W N+ ID F+
Sbjct: 1629 ARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPE---LGSRQDVEALWENMAVIDCFAS 1685
Query: 1717 GSLPTALAAVTGNEIVTGL-GIKEALPLLLSAVNDGRLTIDDIVERLHINPAKIFSI-PE 1774
P L G+ G G++ LPLLL+AV++GRL++DD+++RLH NP +IF + P+
Sbjct: 1686 DHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQ 1745
Query: 1775 QNSAVEVDLDFTFR-------HTKRWSPYQKGGLTGGIQRVLINEETIVLSGDLVATEAK 1827
+++ VEVDL+ + W+P++ + G ++RV++ E + G ++
Sbjct: 1746 EDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGY 1805
Query: 1828 GQPI------LPSKFTPTTPAVAKETPLAAVGTPILGAISTSRKRFSF------------ 1869
GQ + + P+ PA ++ T P G RF
Sbjct: 1806 GQDVRKWPQGAVPQLPPSAPATSEMT--TTPERPRRGIPGLPDGRFHLPPRIHRASDPGL 1863
Query: 1870 -------SNERRLSINSMDGDDEEAILDQPLEQRLMSSRPPKELSAPSVL-INLIRTKNP 1921
+ R+++ + G + P R S P+ L P +L +
Sbjct: 1864 PAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQAS---PQNLGTPGLLHPQTSPLLHS 1920
Query: 1922 FLRRNILSVNQFKRSDFHALFAVAQELRAGVEREGVLDVMKSRVLTTMFYEPSTRTSSSF 1981
+ ++ILSV QF + LF VA LR V++E LD++K +V+ +MFYE STRTSSSF
Sbjct: 1921 LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF 1980
Query: 1982 IAAMERLGGRTVNINTSASSVKKGETLQDTIRTLACYSDAIVLRHPDEMSAHIAAKYSPV 2041
AAM RLGG ++ + + SSV+KGE+L D+++T++CY+D +VLRHP + +AAK+
Sbjct: 1981 AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR 2040
Query: 2042 PIINGGNGSREHPTQAFLDLFTIREELGTVNGITVTFMGDLKFGRPVHSLCRLLQHYQVR 2101
P+IN G+G EHPTQA LD+FTIREELGTVNG+T+T +GDLK GR VHSL LL Y+V
Sbjct: 2041 PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS 2100
Query: 2102 INLIAPKELRLPNALRKELQDSGLLGIESETLTPEIISKSDVLYCTRVQQERFETEEDYL 2161
+ +AP LR+P +R + G E E++ E + +DVLY TR+Q+ERF + ++Y
Sbjct: 2101 LRYVAPPSLRMPPTVRAFVASRGTKQEEFESI-EEALPDTDVLYMTRIQKERFGSTQEYE 2159
Query: 2162 KLKDTYIVDNKILSHAKQQMVVMHPLPRVNEIREEVDYDHRAAYFRQMRYGLFVRMALLA 2221
+I+ I++ AK++MVVMHP+PRVNEI EVD D RAAYFRQ G+++RMALLA
Sbjct: 2160 ACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLA 2219
Query: 2222 MVMG 2225
V+G
Sbjct: 2220 TVLG 2223
>7293258 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2189
Score = 1942 bits (5031), Expect = 0.0
Identities = 1065/2261 (47%), Positives = 1439/2261 (63%), Gaps = 144/2261 (6%)
Query: 24 LELKDGTTLQGYSFG-------AETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPL 76
L L+DGT L GYSFG ++ GE+VFQTGMVGY E++TD SY GQILV+T+PL
Sbjct: 8 LALEDGTVLPGYSFGYVPSENESKVGFGGEVVFQTGMVGYTEALTDRSYSGQILVLTYPL 67
Query: 77 VGNYGVPDRKLMDEYVEGLPRYFESNR--IHVAGLVIAHYTEEYSHWLAQSSLGTWLKES 134
+GNYGVP DE GLP +FE + + LV+ EE HW +L WLK+
Sbjct: 68 IGNYGVP---APDEDEHGLPLHFEWMKGVVQATALVVGEVAEEAFHWRKWKTLPDWLKQH 124
Query: 135 NVPAVYGIDSRSLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDN 194
VP + ID+R+LTK LRE GSMLG+ +KP +S +VDPNV N
Sbjct: 125 KVPGIQDIDTRALTKKLREQGSMLGKIVYEKPPVEGLPKSS-----------FVDPNVRN 173
Query: 195 LVAKVSLKAPKLFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPW 254
L + S+K +++ P+GK RI +D G+K NQ+RC ++RG + ++PW
Sbjct: 174 LAKECSVKERQVY----------GNPNGKGPRIAILDCGLKLNQLRCLLQRGASVTLLPW 223
Query: 255 DYDFTTEEYDGLFISNGPGNPAILQEVSDRLTKVLDAKKTPVFGICLGHQLLARASGAST 314
E++D LF+SNGPGNP ++ ++ KV++ + PVFGICLGHQLLA+A G ST
Sbjct: 224 SARLEDEQFDALFLSNGPGNPESCDQIVQQVRKVIEEGQKPVFGICLGHQLLAKAIGCST 283
Query: 315 LKMKFGNRGHNIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHS 374
KMK+GNRGHN+PC +GRC +TSQNHG+AVD L +GW LF NANDG+NEGI H+
Sbjct: 284 YKMKYGNRGHNLPCLHRATGRCLMTSQNHGYAVDLEQLPDGWSELFVNANDGTNEGIVHA 343
Query: 375 ELPYFSVQFHPESTPGPRDTEFLFDVFIQSVL--DFKQTGVLKQVEFPGGNIEENLAAHP 432
PYFSVQFHPE GP+DTEFLFDVF++S+ D +++Q P ++ P
Sbjct: 344 SKPYFSVQFHPEHHAGPQDTEFLFDVFMESIQQKDLTIPQLIEQRLRPTTPAIDSAPVMP 403
Query: 433 REDXXXXXXXXXXXXXIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADK 492
R+ IGQAGEFDYSGSQAIKA++E I T+LINPNIAT+QTSKG+ADK
Sbjct: 404 RK----VLILGSGGLSIGQAGEFDYSGSQAIKAMRESNIQTVLINPNIATVQTSKGMADK 459
Query: 493 VYFLPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIEMKDE--FETLGVKVLGTPIDTV 550
YFLP+T +V +VI ERP+ + +TFGGQTAL+ G++++ F V++LGTPI ++
Sbjct: 460 CYFLPLTPHYVEQVIKSERPNGVLLTFGGQTALNCGVQLERAGVFSKYNVRILGTPIQSI 519
Query: 551 ITTEDRELFANAMDEINXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFAS 610
I TEDR+LFA ++EI +G+PV+ RAA++LGGLGSGFA+
Sbjct: 520 IETEDRKLFAERVNEIGEQVAPSEAVYSVAQALDAASRLGYPVMARAAFSLGGLGSGFAN 579
Query: 611 NEKELVDLCNVAFASSPQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTG 670
NE+EL L A A S Q++V++S+KGWKE+EYEVVRDA++NCITVCNMENFDPLGIHTG
Sbjct: 580 NEEELQSLAQQALAHSSQLIVDKSLKGWKEVEYEVVRDAYNNCITVCNMENFDPLGIHTG 639
Query: 671 DSIVIAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXX 730
+SIV+APSQTLSD +Y MLR+TA+ VIRH GVVGECNIQYAL P S++Y IIEVN
Sbjct: 640 ESIVVAPSQTLSDREYQMLRSTALKVIRHFGVVGECNIQYALCPHSEQYYIIEVNARLSR 699
Query: 731 XXXXXXXXTGYPLAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKF 790
TGYPLAY AAKL L +PL ++KNSVT +T ACFEPSLDYCVVK+PRWDL KF
Sbjct: 700 SSALASKATGYPLAYVAAKLALGLPLPDIKNSVTGNTTACFEPSLDYCVVKIPRWDLAKF 759
Query: 791 TRVSTLLSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYSNIGFSETDDELDIDY---ELSN 847
RVS + SSMKSVGEVM+IGR FEEA QKA+R + +GF L+ + +LS
Sbjct: 760 VRVSKHIGSSMKSVGEVMAIGRNFEEAFQKALRMVDSDVLGFDPDVVPLNKEQLAEQLSE 819
Query: 848 PSDMRIFAIANAFAKFGYSIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALV 907
P+D R F IA A + G S+ ++ + TNID WFL KL +I ++ GS+ + A +
Sbjct: 820 PTDRRPFVIAAAL-QLGMSLRELHQLTNIDYWFLEKLERIILLQSLLTRNGSRTD--AAL 876
Query: 908 LKQAKQLGFEDRQIAKFLNSNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYN 967
L +AK+ GF D+QIAK++ S E+A+R R+E+GI P VKQIDTVA E+PA TNYLY TYN
Sbjct: 877 LLKAKRFGFSDKQIAKYIKSTELAVRHQRQEFGIRPHVKQIDTVAGEWPASTNYLYHTYN 936
Query: 968 AAAHDLDFNDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTD 1027
+ HD+DF +V+GSGVYRIGSSVEFDWCAV +R LRK TIM+NYNPETVSTD
Sbjct: 937 GSEHDVDFPGGHTIVVGSGVYRIGSSVEFDWCAVGCLRELRKLQRPTIMINYNPETVSTD 996
Query: 1028 YDEADRLYFETINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMI 1087
YD DRLYFE I+ E +MDIYE+E+S G+++SMGGQ NNIAM LHR+ K+LGTSPE I
Sbjct: 997 YDMCDRLYFEEISFEVVMDIYEMENSEGIILSMGGQLPNNIAMDLHRQQAKVLGTSPESI 1056
Query: 1088 DSAENRYKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVY 1147
D AENR+KFSRMLD+ + QP WKELT++ A +F E+V YP LVRPSYVLSGAAMN Y
Sbjct: 1057 DCAENRFKFSRMLDRKGILQPRWKELTNLQSAIEFCEEVGYPCLVRPSYVLSGAAMNVAY 1116
Query: 1148 SKDDLESYLNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHS 1207
S DLE+YLN A EVSRE+PVVI+K++ AKEI++DAVA DG ++ VSEHVENAGVHS
Sbjct: 1117 SNQDLETYLNAASEVSREHPVVISKFLTEAKEIDVDAVASDGRILCMAVSEHVENAGVHS 1176
Query: 1208 GDATLIVPPQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNNEIKVIECNVRASRS 1267
GDATL+ PPQDL+ ET+ I T + L +TGP+N+Q IAKNNE+KVIECNVR SRS
Sbjct: 1177 GDATLVTPPQDLNAETLEAIKRITCDLASVLDVTGPFNMQLIAKNNELKVIECNVRVSRS 1236
Query: 1268 FPFISKVVGVNLIEMATKAIMGIPVTPYPVEKLPDDYVAIKVPQFSFPRLAGADPVLGVE 1327
FPF+SK + + + AT+AI+G+ V P V V +KVPQFSF RLAGAD LGVE
Sbjct: 1237 FPFVSKTLDHDFVATATRAIVGLDVEPLDVLH-GVGKVGVKVPQFSFSRLAGADVQLGVE 1295
Query: 1328 MASTGEVAAFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLPGVKKLYNMGYK 1387
MASTGEVA FG ++YEAYLK++++TGF++PK +LLSIGS+K K ELLP ++ L MGYK
Sbjct: 1296 MASTGEVACFGDNRYEAYLKAMMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKMGYK 1355
Query: 1388 LFATAGTADFISEHGIPVQYLEVLNEEDDEKSEYSLTQHLANNKIDLYINLPSANRFRRP 1447
L+A+ GT DF + + ++ DE+ +
Sbjct: 1356 LYASMGTGDFYA-------XVRPGHQPPDER-----------------------RGCQAV 1385
Query: 1448 ASYVSKGYRTRRMAVDFSVPLVTNVKCAKLLIEALSRNMSLD--VSERDAQTSHRTVTIP 1505
+S+++ GYRTRR+AVD+S+PLVT+VKC KLL+E++ N + D TS R V +P
Sbjct: 1386 SSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVESMRMNGGKPPMKTHTDCMTSRRIVKLP 1445
Query: 1506 GLINISAYV--PNISNVLLGPAELKEVTRLSVESGFTYSQIMPKSSSGPVITDAASLKVA 1563
G I++ ++ P ++ + T ++ G T MP ++ P I D +
Sbjct: 1446 GFIDVHVHLREPGATH----KEDFASGTAAALAGGVTLVCAMP--NTNPSIVDRETFTQF 1499
Query: 1564 NSVVKDSAYTNFGFTVAATPNNIDTVSAVANEATSLFLPYREL-----SNNVPAVSEHLK 1618
+ K A ++ V A+ +N V+ +A+ A L + + +++ + HL
Sbjct: 1500 QELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGTLKLSDMTSWQRHLS 1559
Query: 1619 HWPLDKPVIAEAKTSDLASVILLASLQNRSIHITAVSNKEDLSLVMAVKEKQSNVTCDVN 1678
HWP P++ A+ A+VI+LA L +RS+HI V+ KE++ L+ + KEK VTC+V
Sbjct: 1560 HWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKGVKVTCEVC 1619
Query: 1679 IHSLFVSQDDYPE--------AKFLPTKEDQEFFWSNLESIDAFSIGSLPTALAAVTGNE 1730
H LF+S D L + EDQE W N++ ID F+ P LA
Sbjct: 1620 PHHLFLSTKDVERLGHGMSEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKRSER 1679
Query: 1731 IVTGL-GIKEALPLLLSAVNDGRLTIDDIVERLHINPAKIFSIPEQ-NSAVEVDLDFTFR 1788
G G++ LPLLL AV++GRLT++DI + H NP IF++P+Q + VEVDLD +
Sbjct: 1680 PPPGFPGVETILPLLLQAVHEGRLTMEDIKRKFHRNPKIIFNLPDQAQTYVEVDLDEEWT 1739
Query: 1789 HT-------KRWSPYQKGGLTGGIQRVLINEETIVLSGDLVATEAKGQPILPSKFTPTTP 1841
T W+P++ + G + RV++ E + G ++ GQ + P
Sbjct: 1740 ITGNEMKSKSGWTPFEGTKVKGRVHRVVLRGEVAFVDGQVLVQPGFGQNVRP-------- 1791
Query: 1842 AVAKETPLAA-VGTPILGAISTSRKRFSFSNERRLSINSMDGDDEEAI------LDQPLE 1894
K++PLA+ +L + + + F+ RL + G I +D
Sbjct: 1792 ---KQSPLASEASQDLLPSDNDANDTFT-----RLLTSEGPGGGVHGISTKVHFVDGANF 1843
Query: 1895 QRLMSSRPPKELSAPS---VLINLIRTKN------PFLRRNILSVNQFKRSDFHALFAVA 1945
R S P L + S + L RT N + ++IL+V+ F + + +F +A
Sbjct: 1844 LRPNSPSPRIRLDSASNTTLREYLQRTTNSNPVAHSLMGKHILAVDMFNKDHLNDIFNLA 1903
Query: 1946 QELR-AGVEREGVLDVMKSRVLTTMFYEPSTRTSSSFIAAMERLGGRTVNINTSASSVKK 2004
Q L+ G + V +++ +++ ++FYE STRT SF AAM RLGGR ++++ SSVKK
Sbjct: 1904 QLLKLRGTKDRPVDELLPGKIMASVFYEVSTRTQCSFAAAMLRLGGRVISMDNITSSVKK 1963
Query: 2005 GETLQDTIRTLACYSDAIVLRHPDEMSAHIAAKYSPVPIINGGNGSREHPTQAFLDLFTI 2064
GE+L+D+I+ ++ Y+D +VLRHP + AA +S P+IN G+G EHPTQA LD+FTI
Sbjct: 1964 GESLEDSIKVVSSYADVVVLRHPSPGAVARAATFSRKPLINAGDGVGEHPTQALLDIFTI 2023
Query: 2065 REELGTVNGITVTFMGDLKFGRPVHSLCRLLQHYQVRINLIAPKELRLPNALRKELQDSG 2124
REE GTVNG+T+T +GDLK GR VHSL RLL Y V + +AP L++P+ + + + G
Sbjct: 2024 REEFGTVNGLTITMVGDLKNGRTVHSLARLLTLYNVNLQYVAPNSLQMPDEVVQFVHQRG 2083
Query: 2125 LLGIESETLTPEIISKSDVLYCTRVQQERFETEEDYLKLKDTYIVDNKILSHAKQQMVVM 2184
+ + + L ++ +DVLY TR+Q+ERF+ EDY K ++ + + AK++ +V+
Sbjct: 2084 VKQLFARDL-KNVLPDTDVLYMTRIQRERFDNVEDYEKCCGHLVLTPEHMMRAKKRSIVL 2142
Query: 2185 HPLPRVNEIREEVDYDHRAAYFRQMRYGLFVRMALLAMVMG 2225
HPLPR+NEI E+D D RAAYFRQ YG+++RMALLAMV+G
Sbjct: 2143 HPLPRLNEISREIDSDPRAAYFRQAEYGMYIRMALLAMVVG 2183
>CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2198
Score = 1849 bits (4789), Expect = 0.0
Identities = 1023/2268 (45%), Positives = 1423/2268 (62%), Gaps = 142/2268 (6%)
Query: 23 TLELKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVGNYGV 82
TL L+DG+T G +GA + GE+VFQTGMVGY ES+TDPSY Q+L +T+PL+GNYGV
Sbjct: 4 TLHLEDGSTFVGSIYGATKSVVGEIVFQTGMVGYVESLTDPSYAKQLLTLTYPLIGNYGV 63
Query: 83 PDRKLMDEYVEGLPRYFESNRIHVAGLVIAHYTE--EYSHWLAQSSLGTWLKESNVPAVY 140
P +++D++ LP FES+RI A L++ E+SHW A SL WL++++VP +
Sbjct: 64 PSAEILDQFK--LPAEFESDRIWPAALIVEKICVDGEHSHWQAVQSLSEWLRKADVPCLS 121
Query: 141 GIDSRSLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDNLVAKVS 200
GID R L K +RE G+M + ++ D +VD N +NLV VS
Sbjct: 122 GIDVRQLVKKIRETGTMKAKLVIESDNAQNFD--------------YVDVNAENLVDFVS 167
Query: 201 LKAPKLFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWDYDFTT 260
K P +V G +T I+AVD G+K NQIRC KRG + VVPW++ T
Sbjct: 168 RKEP-----------VVYGSGDQT--ILAVDCGLKNNQIRCLAKRGFRVKVVPWNHPIDT 214
Query: 261 E-EYDGLFISNGPGNPAILQEVSDRLTKVLDAKKTPVFGICLGHQLLARASGASTLKMKF 319
E +YDGLF+SNGPG+P I + DRL KV+ P+FGICLGHQ+L+RA GA T K+K+
Sbjct: 215 ESDYDGLFLSNGPGDPEICAPLVDRLAKVIARGDKPIFGICLGHQILSRAIGAKTYKLKY 274
Query: 320 GNRGHNIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHSELPYF 379
GNRGHN PCT +GRCYITSQNHG+AVD SL WK+LFTN ND +NEGI HS P+F
Sbjct: 275 GNRGHNQPCTHYATGRCYITSQNHGYAVDPDSLPADWKALFTNENDKTNEGIVHSSKPFF 334
Query: 380 SVQFHPESTPGPRDTEFLFDVFIQSVLDFKQTGVLKQVEFPGGNIEENLAAHPREDXXXX 439
SVQFHPE T GP D EFLFDVF SV K +G V+ + + ++
Sbjct: 335 SVQFHPEHTAGPTDCEFLFDVFADSVRQAK-SGTFMNVDQELTRLMTFTPIYHAKEQRKV 393
Query: 440 XXXXXXXXXIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFLPVT 499
IGQAGEFDYSG+QA+KAL+EEGI T+LINPNIAT+QTSKG AD YFLP+T
Sbjct: 394 LVLGSGGLTIGQAGEFDYSGAQALKALREEGIRTVLINPNIATVQTSKGFADFTYFLPIT 453
Query: 500 AEFVRKVILHERPDAIYVTFGGQTALSVGIEMKDE--FETLGVKVLGTPIDTVITTEDRE 557
E+V VI ERP I TFGGQTAL+ I++ + FE V+VLGT I+T++ TEDR+
Sbjct: 454 KEYVTDVIKKERPTGILCTFGGQTALNCAIDLYKDGIFEQYDVQVLGTQINTIMKTEDRD 513
Query: 558 LFANAMDEINXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASNEKELVD 617
LF + I ++G+PV+VRAAYALGGLGSGFA N +EL+
Sbjct: 514 LFNQEISAIGEKVAPSKAATTMEGAIEAAEELGYPVLVRAAYALGGLGSGFADNREELIA 573
Query: 618 LCNVAFASSPQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVIAP 677
+ A A S QVLV++S+KGWKE+EYEVVRDA+DNCITVCNMEN DPLGIHTG+S+V+AP
Sbjct: 574 IAQQALAHSNQVLVDKSLKGWKEVEYEVVRDAYDNCITVCNMENVDPLGIHTGESVVVAP 633
Query: 678 SQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXXXXXXXX 737
SQTLSD +YN LRT A+ VIRHLG++GECNIQYAL+P S Y IIEVN
Sbjct: 634 SQTLSDREYNALRTCAIKVIRHLGIIGECNIQYALDPYSLTYYIIEVNARLSRSSALASK 693
Query: 738 XTGYPLAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKFTRVSTLL 797
TGYPLAY AAKL L L ++NSVT +T ACFEPSLDYCVVK+PRWDL KF RVST +
Sbjct: 694 ATGYPLAYVAAKLALGQHLPVIRNSVTGTTTACFEPSLDYCVVKIPRWDLGKFARVSTQI 753
Query: 798 SSSMKSVGEVMSIGRTFEEAIQKAIRSTEYSNIGFSE-TDDELDIDYELSNPSDMRIFAI 856
SSMKSVGEVM IGR FEEA+QKA+R GFS T +LS P+D R+FA+
Sbjct: 754 GSSMKSVGEVMGIGRCFEEALQKALRMVSDHADGFSPYTFSRPTTADDLSKPTDKRMFAL 813
Query: 857 ANAFAKFGYSIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALVLKQAKQLGF 916
A + +++ E T ID+WFL ++ +++ ++ + A +L +AKQ GF
Sbjct: 814 ARGMYYGDFDVEKAHELTRIDRWFLFRMQNIVDIYHRLEKT-DVNTVSAELLLEAKQAGF 872
Query: 917 EDRQIAKFLNSNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYNAAAHDLDFN 976
DRQIAK + SNE +R R GI P VKQIDTVA E+PA TNYLY T+N +D+ FN
Sbjct: 873 SDRQIAKKIGSNEYTVREARFVKGITPCVKQIDTVAGEWPAQTNYLYTTFNGIENDVSFN 932
Query: 977 -DHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLY 1035
+ VMVLGSGVYRIGSSVEFD V +R L+ + TI VN NPETVSTDYD DRLY
Sbjct: 933 MKNAVMVLGSGVYRIGSSVEFDSSCVGCIRELKALGYSTITVNCNPETVSTDYDICDRLY 992
Query: 1036 FETINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMIDSAENRYK 1095
FE I+ E ++D+Y LE GV+++ GGQ NNIAMSL R VKI GTSP ID+AE+R+K
Sbjct: 993 FEEISFETVLDVYHLEKPKGVILAFGGQAPNNIAMSLSRAQVKIFGTSPNDIDNAEDRFK 1052
Query: 1096 FSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLESY 1155
FSR L+ + + QP WK+ +M++A++F +V YP L+RPSYVLSGAAMN ++ +DLE +
Sbjct: 1053 FSRKLESLKISQPQWKKSENMEDAKNFCAQVGYPCLIRPSYVLSGAAMNVAHNAEDLEVF 1112
Query: 1156 LNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLIVP 1215
L QA V++E+PVV++K+I AKE+++DAVALDG+L++ VSEH+ENAGVHSGDATL+ P
Sbjct: 1113 LKQAAVVAKEHPVVVSKFINEAKELDVDAVALDGKLVVMAVSEHIENAGVHSGDATLVTP 1172
Query: 1216 PQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNNEIKVIECNVRASRSFPFISKVV 1275
QD++ T+ RI + T +I A +TGP+N+Q IAKNNE+KVIECN+R SRSFPF+SK +
Sbjct: 1173 AQDMNKLTLDRIKDITFRIAEAFNVTGPFNMQLIAKNNELKVIECNLRVSRSFPFVSKTL 1232
Query: 1276 GVNLIEMATKAIM-----GIPVTPYPVEKL--PDDYVAIKVPQFSFPRLAGADPVLGVEM 1328
+ + +AT+A+M I T P L V +KVPQFSF RLAGAD +LGVEM
Sbjct: 1233 DYDFVALATRAMMASDSPAIRATIKPTATLLKGKGRVGVKVPQFSFSRLAGADVMLGVEM 1292
Query: 1329 ASTGEVAAFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLPGVKKLYNMGYKL 1388
ASTGEVA FG S+ +AYLK+LL+TGF +PK+NI +SIG Y K E+L V+ L +GY+L
Sbjct: 1293 ASTGEVACFGTSRCDAYLKALLSTGFVVPKQNIFISIGGYHAKAEMLKSVEALLKLGYEL 1352
Query: 1389 FATAGTADFISEHGIPVQYLEVLNEE--DDEKS---EYSLTQHLANNKIDLYINLP-SAN 1442
+ + GTAD+ + I V+ ++ EE DEK+ S+ + L N + L INLP +
Sbjct: 1353 YGSKGTADYFQSNKINVKPVDWPFEEGSSDEKTASGTRSVVEFLENKEFHLVINLPIRGS 1412
Query: 1443 RFRRPASYVSKGYRTRRMAVDFSVPLVTNVKCAKLLIEAL---SRNMSLDVSERDAQTSH 1499
R +++ + GY+TRRMA+D +PL+T++KCAK I+AL + +++ S D TS
Sbjct: 1413 GAYRVSAFRTHGYKTRRMAIDNGIPLITDIKCAKTFIQALEMVGKRPTMN-SLVDCVTSK 1471
Query: 1500 RTVTIPGLINISAYV--PNISNVLLGPAELKEVTRLSVESGFTYSQIMPKSSSGPVITDA 1557
+PG+++I +V P ++ + ++ ++ G T MP +S PV+ D
Sbjct: 1472 SLKRLPGMVDIHVHVREPGATH----KEDWATCSKAALAGGVTTILAMPNTS--PVLVDT 1525
Query: 1558 ASLKVANSVVKDSAYTNFGFTVAATPNNIDTVSAVANEATSLFLPYREL-----SNNVPA 1612
S + + ++ + ATPNN + A++A L + E +N+
Sbjct: 1526 DSFYQTEQLASAKSVVDYALYIGATPNNSKFAAEFADKAAGLKMYLNETFSTLKMDNISD 1585
Query: 1613 VSEHLKHWPLDKPVIAEAKTSDLASVILLASLQNRSIHITAVSNKEDLSLVMAVKEKQSN 1672
++HL +P ++P++ A+ LA+++ +A + NR++HI V+ ++++LV K++ N
Sbjct: 1586 WAKHLSAFPANRPIVCHAEKQTLAAILCMAQMANRAVHIAHVATADEINLVKEAKQRGWN 1645
Query: 1673 VTCDVNIHSLFVSQDDYPEA-----KFLPTKEDQEFFWSNLESIDAFSIGSLPTALAAVT 1727
VTC+V H LF+ ++D P+ L ED++ W N+E ID F+ P A T
Sbjct: 1646 VTCEVCPHHLFLIEEDLPDGIREVRPRLVKPEDRQALWDNMEYIDCFATDHAPHTWAEKT 1705
Query: 1728 GNE--IVTGL-GIKEALPLLLSAVNDGRLTIDDIVERLHINPAKIFSIPEQNSA-VEVDL 1783
G + I G G++ LPLLL+AV+DG+LT+ ++ +R+ NP +IF++P Q+ +EVDL
Sbjct: 1706 GKDGKIPPGFPGVEYMLPLLLTAVHDGKLTMKELTDRMSTNPRRIFNLPPQDDTYIEVDL 1765
Query: 1784 DFTF-------RHTKRWSPYQKGGLTGGIQRVLINEETIVLSGDLVATEAKGQPILPSKF 1836
+ + + W+P+ + G + V+I E V+ G +VA G+ + +
Sbjct: 1766 NEEWTIPENGGQSKAGWTPFAGRKVFGKVHNVIIRGEEAVIDGRIVAIPGFGKNV---RL 1822
Query: 1837 TPTTPAVAKETPLAAVGTPILGAISTSRKRFSFSNERRLSINSMDGDDEEAILDQPLEQR 1896
P + GT G D D ++ + +P+ Q+
Sbjct: 1823 YPHS------------GTAHRG----------------------DSDFDQIL--EPIPQQ 1846
Query: 1897 LMSSRPPKE--LSAPSVLINLIRTKNPFLRRNILSVNQFKRSDFHALFAVAQELRAGVER 1954
++ S ++ L P I L +N +SV + + +F +A + VE+
Sbjct: 1847 MIESSSDEQSPLHTPPRAHTPIAFPGELLAKNCISVKHLDKGQINRIFELADRYKHDVEK 1906
Query: 1955 -EGVLDVMKSRVLTTMFYEPSTRTSSSFIAAMERLGGRTVNINTSASSVKKGETLQDTIR 2013
+ ++ +VL +FYE STRTS SF AAM+RLGG +++++ +SSV+KGETL+DT++
Sbjct: 1907 GHPLTHILNGKVLVNLFYEVSTRTSCSFSAAMQRLGGSVISVDSQSSSVQKGETLEDTVQ 1966
Query: 2014 TLACYSDAIVLRHPDEMSAHIAAKYSPVPIINGGNGSREHPTQAFLDLFTIREELGTVNG 2073
L Y D +VLR + +A AA+ P+INGG+G+ EHPTQA LD++TIR+E+GTVNG
Sbjct: 1967 VLGSYGDILVLRSNENGAADRAARVCDQPVINGGDGTGEHPTQALLDVYTIRQEMGTVNG 2026
Query: 2074 ITVTFMGDLKFGRPVHSLCRLLQHYQ-VRINLIAPK-ELRLPNALRKELQDSGLLGIESE 2131
+T+ +GDLK GR VHSL +LL Y+ + ++ +AP EL +P + + +
Sbjct: 2027 LTIALVGDLKNGRTVHSLAKLLCLYKDITLHYVAPSTELEMPQEVLDYVSSKSNFVQKKF 2086
Query: 2132 TLTPEIISKSDVLYCTRVQQERFETEEDYLKLKDTYIVDNKILSHAKQQM---------- 2181
T E I+ DV+Y TR+Q+ERF + ++Y K+K +Y+++ K+L+ A + +
Sbjct: 2087 TSLAEGINHVDVVYVTRIQKERFSSPDEYNKVKGSYVINAKLLNEAARDVEEPSSLLVPA 2146
Query: 2182 ----VVMHPLPRVNEIREEVDYDHRAAYFRQMRYGLFVRMALLAMVMG 2225
+VMHPLPRV+EI E+D+D RAAYFRQ + G+FVRM++L++++G
Sbjct: 2147 RSLPIVMHPLPRVDEIAVELDHDERAAYFRQAKNGVFVRMSILSLLLG 2194
>Hs21361331 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1500
Score = 1430 bits (3702), Expect = 0.0
Identities = 729/1484 (49%), Positives = 1007/1484 (67%), Gaps = 69/1484 (4%)
Query: 26 LKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVGNYGVPDR 85
L+DGT ++GYSFG ++ AGE+VF TG+ GYPE+ITDP+Y+GQIL + P++GN G PD
Sbjct: 50 LEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDT 109
Query: 86 KLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKESNVPAVYGIDSR 145
+DE GL +Y ESN I V+GL++ Y+++Y+HWLA SLG WL+E VPA+YG+D+R
Sbjct: 110 TALDEL--GLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTR 167
Query: 146 SLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDNLVAKVSLKAPK 205
LTK +R+ G+MLG+ + F VDPN NL+A+VS K K
Sbjct: 168 MLTKIIRDKGTMLGKIEFEGQPVDF-----------------VDPNKQNLIAEVSTKDVK 210
Query: 206 LFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWDYDFTTEEYDG 265
++ +P ++VAVD G+K N IR VKRG E+ +VPW++DFT EYDG
Sbjct: 211 VYGKGNPT------------KVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDG 258
Query: 266 LFISNGPGNPAILQEVSDRLTKVLDA-KKTPVFGICLGHQLLARASGASTLKMKFGNRGH 324
+ I+ GPGNPA+ + + + K+L++ +K P+FGI G+ + A+GA T KM NRG
Sbjct: 259 ILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQ 318
Query: 325 NIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHSELPYFSVQFH 384
N P + + + +IT+QNHG+A+D T L GWK LF N ND +NEGI H P+F+VQFH
Sbjct: 319 NQPVLNITNKQAFITAQNHGYALDNT-LPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFH 377
Query: 385 PESTPGPRDTEFLFDVFIQSVLDFKQTGVLKQVEFPGGNIEENLAAHPREDXXXXXXXXX 444
PE TPGP DTE+LFD F + K T + + P R +
Sbjct: 378 PEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPA-------LVASRVEVSKVLILGS 430
Query: 445 XXXXIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSK-GL--ADKVYFLPVTAE 501
IGQAGEFDYSGSQA+KA+KEE + T+L+NPNIA++QT++ GL AD VYFLP+T +
Sbjct: 431 GGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQ 490
Query: 502 FVRKVILHERPDAIYVTFGGQTALSVGIEM--KDEFETLGVKVLGTPIDTVITTEDRELF 559
FV +VI E+PD + + GGQTAL+ G+E+ + + GVKVLGT +++++ TEDR+LF
Sbjct: 491 FVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLF 550
Query: 560 ANAMDEINXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASNEKELVDLC 619
++ ++EIN IG+PV++R+AYALGGLGSG N + L+DL
Sbjct: 551 SDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLS 610
Query: 620 NVAFASSPQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVIAPSQ 679
AFA + Q+LVE+S+ GWKEIEYEVVRDA DNC+TVCNMEN D +G+HTGDS+V+AP+Q
Sbjct: 611 TKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQ 670
Query: 680 TLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXXXXXXXXXT 739
TLS+ ++ MLR T++NV+RHLG+VGECNIQ+AL+PTS EYCIIEVN T
Sbjct: 671 TLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKAT 730
Query: 740 GYPLAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKFTRVSTLLSS 799
GYPLA+ AAK+ L IPL E+KN V+ T ACFEPSLDY V K+PRWDL +F S+ + S
Sbjct: 731 GYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGS 790
Query: 800 SMKSVGEVMSIGRTFEEAIQKAIRSTEYSNIGFS-------ETDDELDIDYELSNPSDMR 852
SMKSVGEVM+IGRTFEE+ QKA+R S GF+ E LD+ ELS PS R
Sbjct: 791 SMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTR 850
Query: 853 IFAIANAFAKFGYSIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALVLKQAK 912
I+AIA A S+D++ + T IDKWFL K+ ++ + S E++ LK+AK
Sbjct: 851 IYAIAKAIDD-NMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNS-ESMTEETLKRAK 908
Query: 913 QLGFEDRQIAKFLNSNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYNAAAHD 972
++GF D+QI+K L E R LR + I P+VKQIDT+AAE+P+ TNYLY+TYN HD
Sbjct: 909 EIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHD 968
Query: 973 LDFNDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEAD 1032
++F+DHG+MVLG G Y IGSSVEFDWCAV+++RTLR+ KT++VN NPETVSTD+DE D
Sbjct: 969 VNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECD 1028
Query: 1033 RLYFETINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMIDSAEN 1092
+LYFE ++LERI+DIY E+ G ++S+GGQ NN+A+ L++ VKI+GTSP ID AE+
Sbjct: 1029 KLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAED 1088
Query: 1093 RYKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDL 1152
R FS +LD++ V Q WK + +++EA +FA+ V YP L+RPSYVLSG+AMN V+S+D++
Sbjct: 1089 RSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEM 1148
Query: 1153 ESYLNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATL 1212
+ +L +A VS+E+PVV+TK++E A+E+EMDAV DG +I H +SEHVE+AGVHSGDATL
Sbjct: 1149 KKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATL 1208
Query: 1213 IVPPQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNNEIKVIECNVRASRSFPFIS 1272
++P Q + + ++ +AT KI +A I+GP+N+QF+ K N++ VIECN+RASRSFPF+S
Sbjct: 1209 MLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVS 1268
Query: 1273 KVVGVNLIEMATKAIMG-------IPVTPYPVEKLPDDYVAIKVPQFSFPRLAGADPVLG 1325
K +GV+ I++ATK ++G +P +P+ +P DYVAIK P FS+PRL ADP+L
Sbjct: 1269 KTLGVDFIDVATKVMIGENVDEKHLPTLDHPI--IPADYVAIKAPMFSWPRLRDADPILR 1326
Query: 1326 VEMASTGEVAAFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLPGVKKLYNMG 1385
EMASTGEVA FG + A+LK++L+TGFK+P+K IL+ I + L ++L+N G
Sbjct: 1327 CEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEG 1385
Query: 1386 YKLFATAGTADFISEHGIPVQYLEVLNEEDDEKSEYSLTQHLANNKIDLYINLPSANRFR 1445
+KLFAT T+D+++ + +P + ++E S S+ + + + IDL INLP+ N
Sbjct: 1386 FKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNN--- 1442
Query: 1446 RPASYVSKGYRTRRMAVDFSVPLVTNVKCAKLLIEALSRNMSLD 1489
+V Y RR AVD +PL+TN + KL EA+ ++ +D
Sbjct: 1443 --TKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVD 1484
>HsM4503019 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1500
Score = 1409 bits (3646), Expect = 0.0
Identities = 722/1484 (48%), Positives = 1000/1484 (66%), Gaps = 69/1484 (4%)
Query: 26 LKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVGNYGVPDR 85
L+DGT ++GYSFG ++ AGE+VF TG+ GYPE+ITDP+Y+GQIL + P++GN G PD
Sbjct: 50 LEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDT 109
Query: 86 KLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKESNVPAVYGIDSR 145
+DE GL +Y ESN I V+GL++ Y+++Y+HWLA SLG WL+E VPA+YG+D+R
Sbjct: 110 TSLDEL--GLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTR 167
Query: 146 SLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDNLVAKVSLKAPK 205
LTK +R+ G+MLG+ + F VDPN NL+A+VS K K
Sbjct: 168 MLTKIIRDKGTMLGKIEFEGQPVDF-----------------VDPNKQNLIAEVSTKDVK 210
Query: 206 LFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWDYDFTTEEYDG 265
++ +P ++VAVD G+K N IR VKRG E+ +VPW++DFT EYDG
Sbjct: 211 VYGKGNPT------------KVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDG 258
Query: 266 LFISNGPGNPAILQEVSDRLTKVLDA-KKTPVFGICLGHQLLARASGASTLKMKFGNRGH 324
+ I+ GPGNPA+ + + + K+L++ +K P+FGI G+ + A+GA T KM NRG
Sbjct: 259 ILIAGGPGNPALAEPLIQNVQKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQ 318
Query: 325 NIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHSELPYFSVQFH 384
N P + + + +IT+QNH +A+D T L GWK LF N ND +NEGI H P+F+VQFH
Sbjct: 319 NQPVLNITNKQAFITAQNHCYALDNT-LPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFH 377
Query: 385 PESTPGPRDTEFLFDVFIQSVLDFKQTGVLKQVEFPGGNIEENLAAHPREDXXXXXXXXX 444
PE TPGP DTE+LFD F + K T + + P R +
Sbjct: 378 PEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPA-------LVASRVEVSKVLILGS 430
Query: 445 XXXXIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSK-GL--ADKVYFLPVTAE 501
IGQAGEFDYSGSQA+KA+KEE + T+L+NPNIA++QT++ GL AD VYFLP+T +
Sbjct: 431 GGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQ 490
Query: 502 FVRKVILHERPDAIYVTFGGQTALSVGIEM--KDEFETLGVKVLGTPIDTVITTEDRELF 559
FV +VI E+PD + + GGQTAL+ G+E+ + + GVKVLGT +++++ TEDR+LF
Sbjct: 491 FVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLF 550
Query: 560 ANAMDEINXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASNEKELVDLC 619
++ ++EIN IG+PV++R+AYALGGLGSG N + L+DL
Sbjct: 551 SDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLS 610
Query: 620 NVAFASSPQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVIAPSQ 679
AFA + Q+LVE+S+ GWKEIEYEVVRDA DNC+TVCNMEN D +G+HTGDS+V+AP+Q
Sbjct: 611 TKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQ 670
Query: 680 TLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXXXXXXXXXT 739
TLS+ ++ MLR T++NV+RHLG+VGECNIQ+AL+PTS EYCIIEVN T
Sbjct: 671 TLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNAKMSPNSALASKTT 730
Query: 740 GYPLAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKFTRVSTLLSS 799
GYPLA+ AAK+ L IPL +KN V+ T ACFEPSLDY V K+PRWDL +F S+ + S
Sbjct: 731 GYPLAFIAAKIALGIPLPGIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGS 790
Query: 800 SMKSVGEVMSIGRTFEEAIQKAIRSTEYSNIGFS-------ETDDELDIDYELSNPSDMR 852
SMKSVGEVM+IGRTFEE+ QKA+R S GF+ E LD+ ELS PS R
Sbjct: 791 SMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTR 850
Query: 853 IFAIANAFAKFGYSIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALVLKQAK 912
I+AIA A S+D++ + T IDKWFL K+ ++ + S E++ LK+AK
Sbjct: 851 IYAIAKAIDD-NMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNS-ESMTEETLKRAK 908
Query: 913 QLGFEDRQIAKFLNSNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYNAAAHD 972
++GF D+QI+K L E R LR + I P+VKQIDT+AAE+P+ TNYLY+TYN HD
Sbjct: 909 EIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHD 968
Query: 973 LDFNDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEAD 1032
++F+DHG+MVLG G Y IGSSVEFDWCAV+++RTLR+ KT++VN NPETVSTD+DE D
Sbjct: 969 VNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECD 1028
Query: 1033 RLYFETINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMIDSAEN 1092
+LYFE ++LERI+DIY E+ G ++S+GGQ NN+A+ L++ VKI+GTSP ID AE+
Sbjct: 1029 KLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAED 1088
Query: 1093 RYKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDL 1152
R FS +LD++ V Q WK + +++EA +FA+ V YP L+RPSYVLSG+AMN V+S+D++
Sbjct: 1089 RSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEM 1148
Query: 1153 ESYLNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATL 1212
+ +L +A VS+ PVV+TK++E A+E+EMDAV DG +I H +SEHVE+AGVHS +ATL
Sbjct: 1149 KKFLEEATRVSQATPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSENATL 1208
Query: 1213 IVPPQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNNEIKVIECNVRASRSFPFIS 1272
++P Q + + ++ +AT KI +A I+GP+N+QF+ K N++ V ECN+RASRSFP +S
Sbjct: 1209 MLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVNECNLRASRSFPSVS 1268
Query: 1273 KVVGVNLIEMATKAIMG-------IPVTPYPVEKLPDDYVAIKVPQFSFPRLAGADPVLG 1325
K +GV+ I++ATK ++G +P +P+ +P DYVAIK P FS+PRL ADP+L
Sbjct: 1269 KTLGVDFIDVATKVLIGENVDEKHLPTLDHPI--IPVDYVAIKAPMFSWPRLRDADPILR 1326
Query: 1326 VEMASTGEVAAFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLPGVKKLYNMG 1385
EMASTGEVA FG + A+LK++L+TGFK+P+K IL+ I + L ++L+N G
Sbjct: 1327 CEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEG 1385
Query: 1386 YKLFATAGTADFISEHGIPVQYLEVLNEEDDEKSEYSLTQHLANNKIDLYINLPSANRFR 1445
+KLFAT T+D+++ + +P + ++E S S+ + + + IDL INLP+ N
Sbjct: 1386 FKLFATEATSDWLNANNVPANPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNN--- 1442
Query: 1446 RPASYVSKGYRTRRMAVDFSVPLVTNVKCAKLLIEALSRNMSLD 1489
+V Y RR AVD +PL+TN + KL EA+ ++ +D
Sbjct: 1443 --TKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVD 1484
>SPBC215.08c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1160
Score = 1095 bits (2832), Expect = 0.0
Identities = 575/1062 (54%), Positives = 744/1062 (69%), Gaps = 26/1062 (2%)
Query: 449 IGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFLPVTAEFVRKVIL 508
IGQAGEFDYSG+QAIKAL+E ++TILINPNIATIQ+S LAD++YFLPVTAE++ +I
Sbjct: 99 IGQAGEFDYSGAQAIKALRESSVHTILINPNIATIQSSHSLADEIYFLPVTAEYLTHLIE 158
Query: 509 HERPDAIYVTFGGQTALSVGIEMKDE--FETLGVKVLGTPIDTVITTEDRELFANAMDEI 566
E PD I +TFGGQTAL+VGI++ D F VKVLGTPI T+ T+EDR+LFA A++EI
Sbjct: 159 RENPDGILLTFGGQTALNVGIQLDDMGVFARNHVKVLGTPISTLKTSEDRDLFAKALNEI 218
Query: 567 NXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASNEKELVDLCNVAFASS 626
N + +PVI+R+AY+LGGLGSGFA+N++EL + + + +
Sbjct: 219 NIPIAESVAVSTVDEALQAAEKVSYPVIIRSAYSLGGLGSGFANNKEELQSMAAKSLSLT 278
Query: 627 PQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVIAPSQTLSDEDY 686
PQ+LVE+S+KGWKE+EYEVVRDA +NCITVCNMENFDPLGIHTGDSIV+APSQTLSDE+Y
Sbjct: 279 PQILVEKSLKGWKEVEYEVVRDAANNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEEY 338
Query: 687 NMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXXXXXXXXXTGYPLAYT 746
+MLRT A+ +IRHLGVVGECN+QYAL+P S EY +IEVN TGYPLAYT
Sbjct: 339 HMLRTAAIKIIRHLGVVGECNVQYALSPNSLEYRVIEVNARLSRSSALASKATGYPLAYT 398
Query: 747 AAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKFTRVSTLLSSSMKSVGE 806
AAK+ L L E+ N+VT++T A FEPSLDY V K+PRWDL KF V+ + SSMKSVGE
Sbjct: 399 AAKIALGHTLPELPNAVTKTTTANFEPSLDYVVTKIPRWDLSKFQYVNREIGSSMKSVGE 458
Query: 807 VMSIGRTFEEAIQKAIRSTEYSNIGFSETDDELDIDYELSNPSDMRIFAIANAFAKFGYS 866
VM++GRTFEE++QKA+R + S +GF + D+D LS P+D R FA+ A GYS
Sbjct: 459 VMAVGRTFEESLQKALRQVDPSFLGFMAMPFK-DLDNALSVPTDRRFFAVVEAMLNQGYS 517
Query: 867 IDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALVLKQAKQLGFEDRQIAKFLN 926
ID++ + T IDKWFL+KL ++ K ++ GS L ++ +AK+ GF D QI+K +
Sbjct: 518 IDKIHDLTKIDKWFLSKLANMAKVYKELEEIGSLYGLNKEIMLRAKKTGFSDLQISKLVG 577
Query: 927 SNEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYNAAAHDLDFNDHGVMVLGSG 986
++E+ +R RK + P+VK+IDT+AAEFPAHTNYLY +YNA++HD+DFN+HG MVLGSG
Sbjct: 578 ASELDVRARRKRLDVHPWVKKIDTLAAEFPAHTNYLYTSYNASSHDIDFNEHGTMVLGSG 637
Query: 987 VYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYFETINLERIMD 1046
VYRIGSSVEFDWC V+ RTLRK TIMVNYNPETVSTD+DE +RLYFE ++ ER+MD
Sbjct: 638 VYRIGSSVEFDWCGVSCARTLRKLGHSTIMVNYNPETVSTDFDECERLYFEELSYERVMD 697
Query: 1047 IYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMIDSAENRYKFSRMLDQIDVD 1106
IYE+E+++G+VVS+GGQ NIA+ L K+LGT P MIDSAE+R+KFS++LD+I VD
Sbjct: 698 IYEMETASGIVVSVGGQLPQNIALKLQETGAKVLGTDPLMIDSAEDRHKFSQILDKIGVD 757
Query: 1107 QPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLESYLNQAVEVSREY 1166
QPAWKELTS+ EA FA V YPVLVRPSYVLSGAAM+ + + L+ L A VS ++
Sbjct: 758 QPAWKELTSVAEASKFANAVGYPVLVRPSYVLSGAAMSVIRDESSLKDKLENASAVSPDH 817
Query: 1167 PVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLIVPPQDLDPETVRR 1226
PVVITK+IE A+E+++DAVA G+L++H VSEHVENAGVHSGDAT+ +PP L + + R
Sbjct: 818 PVVITKFIEGARELDVDAVASKGKLLVHAVSEHVENAGVHSGDATIALPPYSLSEDILSR 877
Query: 1227 IVEATAKIGRALQITGPYNIQFIAKNN-------EIKVIECNVRASRSFPFISKVVGVNL 1279
E K+ +A QITGPYN+Q I N ++KVIECN+RASRSFPF+SK +GVN
Sbjct: 878 CKEIAEKVCKAFQITGPYNMQIILAQNPDKPDTPDLKVIECNLRASRSFPFVSKTLGVNF 937
Query: 1280 IEMATKAIMGIPV-TPYPVEKLPDDYVAIKVPQFSFPRLAGADPVLGVEMASTGEVAAFG 1338
I++AT++I+ V + + DYV +KVPQFS+ RLAGADP LGVEM+STGEVA FG
Sbjct: 938 IDVATRSIIDQEVPAARDLMAVHRDYVCVKVPQFSWTRLAGADPYLGVEMSSTGEVACFG 997
Query: 1339 HSKYEAYLKSLLAT-GFKLPKKNILLSIGSYKEKQELLPGVKKLYNMGYKLF-ATAGTAD 1396
EAY +L +T FK+P + +G ++ EL L +GYKL+ A A
Sbjct: 998 KDVKEAYWAALQSTQNFKIPLPGQGILLGG--DRPELAGIAADLSKLGYKLYVANKDAAK 1055
Query: 1397 FISEHGIPVQYLEVLNEEDDEKSEYSLTQHLANNKIDLYINLPSANRFRRPASYVSKGYR 1456
+ V V K + +L I NL SA R + + + Y
Sbjct: 1056 LLQPTSAEVVEFPV-------KDKRALRAIFEKYNIRSVFNLASA----RGKNVLDQDYV 1104
Query: 1457 TRRMAVDFSVPLVTNVKCAKLLIEALSRNMSLDVSERDAQTS 1498
RR AVDF+V L+ +V CAKL +E+L + +SE+ S
Sbjct: 1105 MRRNAVDFNVTLINDVNCAKLFVESLKEKLPSVLSEKKEMPS 1146
Score = 194 bits (492), Expect = 2e-48
Identities = 129/432 (29%), Positives = 221/432 (50%), Gaps = 25/432 (5%)
Query: 980 VMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYFETI 1039
V+V+GSG IG + EFD+ A++ LR+++ TI++N N T+ + + AD +YF +
Sbjct: 89 VVVVGSGGLSIGQAGEFDYSGAQAIKALRESSVHTILINPNIATIQSSHSLADEIYFLPV 148
Query: 1040 NLERIMDIYELESSAGVVVSMGGQTSNNIAMSLH------RENVKILGTSPEMIDSAENR 1093
E + + E E+ G++++ GGQT+ N+ + L R +VK+LGT + ++E+R
Sbjct: 149 TAEYLTHLIERENPDGILLTFGGQTALNVGIQLDDMGVFARNHVKVLGTPISTLKTSEDR 208
Query: 1094 YKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLE 1153
F++ L++I++ ++++DEA AEKVSYPV++R +Y L G +K++L+
Sbjct: 209 DLFAKALNEINIPIAESVAVSTVDEALQAAEKVSYPVIIRSAYSLGGLGSGFANNKEELQ 268
Query: 1154 SYLNQAVEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVS-EHVENAGVHSGDATL 1212
S +++ ++ + +++ K ++ KE+E + V + V + E+ + G+H+GD+ +
Sbjct: 269 SMAAKSLSLTPQ--ILVEKSLKGWKEVEYEVVRDAANNCITVCNMENFDPLGIHTGDSIV 326
Query: 1213 IVPPQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNN--EIKVIECNVRASRSFPF 1270
+ P Q L E + A KI R L + G N+Q+ N E +VIE N R SRS
Sbjct: 327 VAPSQTLSDEEYHMLRTAAIKIIRHLGVVGECNVQYALSPNSLEYRVIEVNARLSRSSAL 386
Query: 1271 ISKVVGVNLIEMATKAIMG--IPVTPYPVEKLPD-------DYVAIKVPQFSFPRLAGAD 1321
SK G L A K +G +P P V K DYV K+P++ + +
Sbjct: 387 ASKATGYPLAYTAAKIALGHTLPELPNAVTKTTTANFEPSLDYVVTKIPRWDLSKFQYVN 446
Query: 1322 PVLGVEMASTGEVAAFGHSKYEAYLKSLLAT-----GFKLPKKNILLSIGSYKEKQELLP 1376
+G M S GEV A G + E+ K+L GF L + S +
Sbjct: 447 REIGSSMKSVGEVMAVGRTFEESLQKALRQVDPSFLGFMAMPFKDLDNALSVPTDRRFFA 506
Query: 1377 GVKKLYNMGYKL 1388
V+ + N GY +
Sbjct: 507 VVEAMLNQGYSI 518
>YJR109c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1118
Score = 1055 bits (2727), Expect = 0.0
Identities = 548/1053 (52%), Positives = 729/1053 (69%), Gaps = 18/1053 (1%)
Query: 449 IGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFLPVTAEFVRKVIL 508
IGQAGEFDYSGSQAIKALKE+ +TIL+NPNIAT QTS LADK+Y+LPVT E++ +I
Sbjct: 41 IGQAGEFDYSGSQAIKALKEDNKFTILVNPNIATNQTSHSLADKIYYLPVTPEYITYIIE 100
Query: 509 HERPDAIYVTFGGQTALSVGIEMKDE--FETLGVKVLGTPIDTVITTEDRELFANAMDEI 566
ERPDAI +TFGGQT L+ G+ + + VKVLGTPI T+IT+EDR+LFA+A+ +I
Sbjct: 101 LERPDAILLTFGGQTGLNCGVALDESGVLAKYNVKVLGTPIKTLITSEDRDLFASALKDI 160
Query: 567 NXXXXXXXXXXXXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASNEKELVDLCNVAFASS 626
N + +PVIVR+AYALGGLGSGFA+N E+ +L + + +
Sbjct: 161 NIPIAESFACETVDEALEAAERVKYPVIVRSAYALGGLGSGFANNASEMKELAAQSLSLA 220
Query: 627 PQVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVIAPSQTLSDEDY 686
PQ+LVE+S+KGWKE+EYEVVRD NCITVCNMENFDPLG+HTGDS+V APSQTLSDE++
Sbjct: 221 PQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGVHTGDSMVFAPSQTLSDEEF 280
Query: 687 NMLRTTAVNVIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXXXXXXXXXTGYPLAYT 746
+MLR+ A+ +IRHLGV+GECN+QYAL P +Y +IEVN TGYPLAYT
Sbjct: 281 HMLRSAAIKIIRHLGVIGECNVQYALQPDGLDYRVIEVNARLSRSSALASKATGYPLAYT 340
Query: 747 AAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVKMPRWDLKKFTRVSTLLSSSMKSVGE 806
AAK+GL L E+ N +T++T A FEPSLDY V K+P+WDL KF V + SSMKSVGE
Sbjct: 341 AAKIGLGYTLPELPNPITKTTVANFEPSLDYIVAKIPKWDLSKFQYVDRSIGSSMKSVGE 400
Query: 807 VMSIGRTFEEAIQKAIRSTEYSNIGFSETDDELD-IDYELSNPSDMRIFAIANAFAKFGY 865
VM+IGR +EEA QKA+R + S +GF + + D +D L P+D R+ AI A Y
Sbjct: 401 VMAIGRNYEEAFQKALRQVDPSLLGFQGSTEFGDQLDEALRTPTDRRVLAIGQALIHENY 460
Query: 866 SIDQVWEKTNIDKWFLNKLYSLIKFSDKISSYGSKENLPALVLKQAKQLGFEDRQIAKFL 925
++++V E + IDKWFL K +++ ++ S S +L +L++AK+LGF D+QIA +
Sbjct: 461 TVERVNELSKIDKWFLYKCMNIVNIYKELESVKSLSDLSKDLLQRAKKLGFSDKQIAVTI 520
Query: 926 NS------NEVAIRRLRKEYGIIPFVKQIDTVAAEFPAHTNYLYLTYNAAAHDLDFNDHG 979
N NE+ IR LRK GIIPFVK+IDT+AAEFPA TNYLY TYNA +D++FN++G
Sbjct: 521 NKHASTNINELEIRSLRKTLGIIPFVKRIDTLAAEFPAQTNYLYTTYNATKNDVEFNENG 580
Query: 980 VMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYFETI 1039
++VLGSGVYRIGSSVEFDWCAV +TLR KTIM+NYNPETVSTD+DE DRLYFE +
Sbjct: 581 MLVLGSGVYRIGSSVEFDWCAVNTAKTLRDQGKKTIMINYNPETVSTDFDEVDRLYFEEL 640
Query: 1040 NLERIMDIYELESSAGVVVSMGGQTSNNIAMSLHRENVKILGTSPEMIDSAENRYKFSRM 1099
+ ER+MDIYELE S G ++S+GGQ NIA+ L+ I+GT+P ID AENR+KFS +
Sbjct: 641 SYERVMDIYELEQSEGCIISVGGQLPQNIALKLYDNGCNIMGTNPNDIDRAENRHKFSSI 700
Query: 1100 LDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLESYLNQA 1159
LD IDVDQP W ELTS++EA+ FA KV+YPVL+RPSYVLSGAAM+ V ++++L++ L A
Sbjct: 701 LDSIDVDQPEWSELTSVEEAKLFASKVNYPVLIRPSYVLSGAAMSVVNNEEELKAKLTLA 760
Query: 1160 VEVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLIVPPQDL 1219
+VS ++PVV++K+IE A+EI++DAVA +G +++H +SEHVENAGVHSGDA+L++PPQ L
Sbjct: 761 SDVSPDHPVVMSKFIEGAQEIDVDAVAYNGNVLVHAISEHVENAGVHSGDASLVLPPQHL 820
Query: 1220 DPETVRRIVEATAKIGRALQITGPYNIQFIAK-NNEIKVIECNVRASRSFPFISKVVGVN 1278
+ + + K+ +A +ITGP+N+Q I + +KVIECN+RASRSFPF+SKV+GVN
Sbjct: 821 SDDVKIALKDIADKVAKAWKITGPFNMQIIKDGEHTLKVIECNIRASRSFPFVSKVLGVN 880
Query: 1279 LIEMATKAIMGIPVTPYPVEKLPD---DYVAIKVPQFSFPRLAGADPVLGVEMASTGEVA 1335
IE+A KA +G + P PV+ + + DYVA KVPQFSF RLAGADP LGVEMASTGEVA
Sbjct: 881 FIEIAVKAFLGGDIVPKPVDLMLNKKYDYVATKVPQFSFTRLAGADPFLGVEMASTGEVA 940
Query: 1336 AFGHSKYEAYLKSLLAT-GFKLPKKNILLSIGSYKEKQELLPGVKKLYNMGYKLFATAGT 1394
+FG E+Y ++ +T F +P + G ++ L + +GY+++ T T
Sbjct: 941 SFGRDLIESYWTAIQSTMNFHVPLPPSGILFGGDTSREYLGQVASIVATIGYRIYTTNET 1000
Query: 1395 ADFISEHGIPVQYLEVLNEEDDEKSEYSLTQHLANNKIDLYINLPSANRFRRPASYVSKG 1454
+ I + +V + + + L + I NL S +R S
Sbjct: 1001 TKTYLQEHIKEKNAKVSLIKFPKNDKRKLRELFQEYDIKAVFNLAS----KRAESTDDVD 1056
Query: 1455 YRTRRMAVDFSVPLVTNVKCAKLLIEALSRNMS 1487
Y RR A+DF++PL + A L + L ++
Sbjct: 1057 YIMRRNAIDFAIPLFNEPQTALLFAKCLKAKIA 1089
Score = 183 bits (464), Expect = 3e-45
Identities = 122/390 (31%), Positives = 201/390 (51%), Gaps = 20/390 (5%)
Query: 978 HGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYFE 1037
+ V+V+GSG IG + EFD+ A++ L+++N TI+VN N T T + AD++Y+
Sbjct: 29 NSVLVIGSGGLSIGQAGEFDYSGSQAIKALKEDNKFTILVNPNIATNQTSHSLADKIYYL 88
Query: 1038 TINLERIMDIYELESSAGVVVSMGGQTSNNIAMSLH------RENVKILGTSPEMIDSAE 1091
+ E I I ELE ++++ GGQT N ++L + NVK+LGT + + ++E
Sbjct: 89 PVTPEYITYIIELERPDAILLTFGGQTGLNCGVALDESGVLAKYNVKVLGTPIKTLITSE 148
Query: 1092 NRYKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDD 1151
+R F+ L I++ ++DEA + AE+V YPV+VR +Y L G + +
Sbjct: 149 DRDLFASALKDINIPIAESFACETVDEALEAAERVKYPVIVRSAYALGGLGSGFANNASE 208
Query: 1152 LESYLNQAVEVSREYPVVITKYIENAKEIEMDAVA-LDGELIMHVVSEHVENAGVHSGDA 1210
++ Q++ ++ + +++ K ++ KE+E + V G I E+ + GVH+GD+
Sbjct: 209 MKELAAQSLSLAPQ--ILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGVHTGDS 266
Query: 1211 TLIVPPQDLDPETVRRIVEATAKIGRALQITGPYNIQFIAKNN--EIKVIECNVRASRSF 1268
+ P Q L E + A KI R L + G N+Q+ + + + +VIE N R SRS
Sbjct: 267 MVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALQPDGLDYRVIEVNARLSRSS 326
Query: 1269 PFISKVVGVNLIEMATKAIMG--IPVTPYPVEKLPD-------DYVAIKVPQFSFPRLAG 1319
SK G L A K +G +P P P+ K DY+ K+P++ +
Sbjct: 327 ALASKATGYPLAYTAAKIGLGYTLPELPNPITKTTVANFEPSLDYIVAKIPKWDLSKFQY 386
Query: 1320 ADPVLGVEMASTGEVAAFGHSKYEAYLKSL 1349
D +G M S GEV A G + EA+ K+L
Sbjct: 387 VDRSIGSSMKSVGEVMAIGRNYEEAFQKAL 416
>YOR303w [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 411
Score = 343 bits (880), Expect = 2e-93
Identities = 182/389 (46%), Positives = 234/389 (59%), Gaps = 33/389 (8%)
Query: 23 TLELKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVGNYGV 82
T +++G + +G SFGA + AGE VF T +VGYPES+TDPSY GQILV T PL+GNYGV
Sbjct: 9 TFCIQNGPSFEGISFGANKSVAGETVFTTSLVGYPESMTDPSYRGQILVFTQPLIGNYGV 68
Query: 83 PDRKLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKESNVPAVYGI 142
P + DEY L +YFES IHV G+V+A Y +YSHW A SL W + V A+ G+
Sbjct: 69 PSGEARDEY--NLLKYFESPHIHVVGIVVAEYAYQYSHWTAVESLAQWCQREGVAAITGV 126
Query: 143 DSRSLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDNLVAKVSLK 202
D+R L ++LRE GS LGR L + +V+P NLVA+V+ K
Sbjct: 127 DTRELVQYLREQGSSLGRITLAD----------------HDPVPYVNPMKTNLVAQVTTK 170
Query: 203 APKLFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWDYDF--TT 260
P + P + +D G+K N IRC VKRG + V P+DY
Sbjct: 171 KP---------FHVSALPGKAKANVALIDCGVKENIIRCLVKRGANVTVFPYDYRIQDVA 221
Query: 261 EEYDGLFISNGPGNPAILQEVSDRLTKVLDAKK---TPVFGICLGHQLLARASGASTLKM 317
E+DG+F+SNGPGNP + Q + ++L+ P+FGICLGHQLLA ASGAST K+
Sbjct: 222 SEFDGIFLSNGPGNPELCQATISNVRELLNNPVYDCIPIFGICLGHQLLALASGASTHKL 281
Query: 318 KFGNRGHNIPCTSTVSGRCYITSQNHGFAVD-ETSLTNGWKSLFTNANDGSNEGIYHSEL 376
K+GNR HNIP +G+C+ITSQNHG+AVD ET + WK F N ND SNEG+ H +
Sbjct: 282 KYGNRAHNIPAMDLTTGQCHITSQNHGYAVDPETLPKDQWKPYFVNLNDKSNEGMIHLQR 341
Query: 377 PYFSVQFHPESTPGPRDTEFLFDVFIQSV 405
P FS QFHPE+ GP DT LFD F ++
Sbjct: 342 PIFSTQFHPEAKGGPLDTAILFDKFFDNI 370
>SPBC56F2.09c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 415
Score = 334 bits (856), Expect = 1e-90
Identities = 176/395 (44%), Positives = 242/395 (60%), Gaps = 27/395 (6%)
Query: 19 DRMITLELKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVG 78
+ + TL +++G G SFGA +GE VF T VGY ES+TDPSY+ QIL+ T PL+G
Sbjct: 43 NEIATLTIRNGPIFHGTSFGANRNVSGEAVFTTSPVGYVESLTDPSYKQQILIFTQPLIG 102
Query: 79 NYGVPDRKLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKESNVPA 138
NYGVPD K DE GL R+FES I AG+V+ Y +YSHW A SLG W V A
Sbjct: 103 NYGVPDCKKRDE--NGLLRHFESPHIQCAGVVVNDYATKYSHWTAVESLGEWCAREGVAA 160
Query: 139 VYGIDSRSLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDNLVAK 198
+ G+D+R++ LRE GS L + ++ G + DAN E +++P NLV++
Sbjct: 161 ITGVDTRAIVTFLREQGSSLAKISI---GEEY-DANDDE--------AFINPEEVNLVSQ 208
Query: 199 VSLKAPKLFVPNHPDIDLVQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWDYDF 258
VS + P V G DG L I +D G+K N +R V RG + V P+DY
Sbjct: 209 VSTREPFF----------VSGGDGM-LNIAVIDCGVKENILRSLVSRGASVTVFPFDYPI 257
Query: 259 --TTEEYDGLFISNGPGNPAILQEVSDRLTKVLDAKKTPVFGICLGHQLLARASGASTLK 316
YDG+F++NGPG+P L + + L ++++ P+ GIC+GHQLLA ++GA T+K
Sbjct: 258 QNVASNYDGIFLTNGPGDPTHLTKTVNNLRELMNTYNGPIMGICMGHQLLALSTGAKTIK 317
Query: 317 MKFGNRGHNIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHSEL 376
+K+GNRGHNIP SG C+ITSQNHG+AVD ++L WK+ +TN ND SNEGI H
Sbjct: 318 LKYGNRGHNIPALDIASGNCHITSQNHGYAVDASTLPAEWKATWTNLNDQSNEGIAHVSR 377
Query: 377 PYFSVQFHPESTPGPRDTEFLFDVFIQSVLDFKQT 411
P SVQFHPE+ GP DT +LFD +I+ + ++++
Sbjct: 378 PISSVQFHPEARGGPMDTFYLFDNYIKEAIKYQKS 412
>At1g29900 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 956
Score = 287 bits (735), Expect = 1e-76
Identities = 153/339 (45%), Positives = 206/339 (60%), Gaps = 6/339 (1%)
Query: 449 IGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFLPVTAEFVRKVIL 508
IGQA EFDYSG+QA KAL+EEG ILIN N ATI T A++ Y P+T E V +VI
Sbjct: 111 IGQACEFDYSGTQACKALREEGYEVILINSNPATIMTDPETANRTYIAPMTPELVEQVIE 170
Query: 509 HERPDAIYVTFGGQTALSVGIEMKDE--FETLGVKVLGTPIDTVITTEDRELFANAMDEI 566
ERPDA+ T GGQTAL++ + + + E GV+++G + + EDRELF +AM I
Sbjct: 171 KERPDALLPTMGGQTALNLAVALAESGALEKYGVELIGAKLGAIKKAEDRELFKDAMKNI 230
Query: 567 NXXXXXXXXXXXXXXXXXXXXDIG-FPVIVRAAYALGGLGSGFASNEKELVDLCNVAFAS 625
IG FP+I+R A+ LGG G G A N++E +C A+
Sbjct: 231 GLKTPPSGIGTTLDECFDIAEKIGEFPLIIRPAFTLGGTGGGIAYNKEEFESICKSGLAA 290
Query: 626 SP--QVLVERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVIAPSQTLSD 683
S QVLVE+S+ GWKE E EV+RD DN + +C++EN DP+G+HTGDSI +AP+QTL+D
Sbjct: 291 SATSQVLVEKSLLGWKEYELEVMRDLADNVVIICSIENIDPMGVHTGDSITVAPAQTLTD 350
Query: 684 EDYNMLRTTAVNVIRHLGV-VGECNIQYALNPTSKEYCIIEVNXXXXXXXXXXXXXTGYP 742
+Y LR ++ +IR +GV G N+Q+A+NP E IIE+N TG+P
Sbjct: 351 REYQRLRDYSIAIIREIGVECGGSNVQFAVNPVDGEVMIIEMNPRVSRSSALASKATGFP 410
Query: 743 LAYTAAKLGLNIPLYEVKNSVTRSTCACFEPSLDYCVVK 781
+A AAKL + L ++ N +TR T A FEPS+DY V K
Sbjct: 411 IAKMAAKLSVGYTLDQIPNDITRKTPASFEPSIDYVVTK 449
Score = 281 bits (718), Expect = 1e-74
Identities = 169/487 (34%), Positives = 269/487 (54%), Gaps = 26/487 (5%)
Query: 1012 FKTIMVNYNPETVSTDYDEADRLYFETINLERIMDIYELESSAGVVVSMGGQTSNNIAMS 1071
++TIM+N NPETVSTDYD +DRLYFE + +E ++++ +LE G++V GGQT +A+
Sbjct: 453 YETIMLNSNPETVSTDYDTSDRLYFEPLTIEDVLNVIDLEKPDGIIVQFGGQTPLKLALP 512
Query: 1072 LHRE-------------NVKILGTSPEMIDSAENRYKFSRMLDQIDVDQPAWKELTSMDE 1118
+ V+I GTSP+ ID+AE+R +F+ +LD++ ++QP S +
Sbjct: 513 IKHYLDKHMPMSLSGAGPVRIWGTSPDSIDAAEDRERFNAILDELKIEQPKGGIAKSEAD 572
Query: 1119 AEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLESYLNQAVEVSREYPVVITKYIENAK 1178
A A++V YPV+VRPSYVL G AM VY L +YL AV+V E PV++ KY+ +A
Sbjct: 573 ALAIAKEVGYPVVVRPSYVLGGRAMEIVYDDSRLITYLENAVQVDPERPVLVDKYLSDAI 632
Query: 1179 EIEMDAVALD-GELIMHVVSEHVENAGVHSGDATLIVPPQDLDPETVRRIVEATAKIGRA 1237
EI++D + G +++ + EH+E AGVHSGD+ ++P Q + ++ I T K+ +
Sbjct: 633 EIDVDTLTDSYGNVVIGGIMEHIEQAGVHSGDSACMLPTQTIPASCLQTIRTWTTKLAKK 692
Query: 1238 LQITGPYNIQF-IAKNNEIKVIECNVRASRSFPFISKVVGVNLIEMATKAIMGIPVTPYP 1296
L + G N Q+ I + ++ ++E N RASR+ PF+SK +G L + A + G +
Sbjct: 693 LNVCGLMNCQYAITTSGDVFLLEANPRASRTVPFVSKAIGHPLAKYAALVMSGKSLKDLN 752
Query: 1297 VEK-LPDDYVAIKVPQFSFPRLAGADPVLGVEMASTGEVAAFGHSKYEAYLKSLLATGFK 1355
EK + +V++K F F + G D +LG EM STGEV + A+ + +A G K
Sbjct: 753 FEKEVIPKHVSVKEAVFPFEKFQGCDVILGPEMRSTGEVMSISSEFSSAFAMAQIAAGQK 812
Query: 1356 LPKKNILLSIGSYKEKQELLPGVKKLYNMGYKLFATAGTADFISEHGIPVQYLEVLNEED 1415
LP + + K L +G+K+ AT+GTA F+ GIPV+ + L+E
Sbjct: 813 LPLSGTVFLSLNDMTKPHLEKIAVSFLELGFKIVATSGTAHFLELKGIPVERVLKLHEGR 872
Query: 1416 DEKSEYSLTQHLANNKIDLYINLPSANRFRRPASYVSKGYRTRRMAVDFSVPLVTNVKCA 1475
++ +AN +I L + S + + G + R+MA+ + VP++T V A
Sbjct: 873 PHAADM-----VANGQIHLMLITSSGDALDQ-----KDGRQLRQMALAYKVPVITTVAGA 922
Query: 1476 KLLIEAL 1482
E +
Sbjct: 923 LATAEGI 929
Score = 164 bits (415), Expect = 1e-39
Identities = 99/335 (29%), Positives = 176/335 (51%), Gaps = 16/335 (4%)
Query: 980 VMVLGSGVYRIGSSVEFDWCAVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYFETI 1039
+M+LG+G IG + EFD+ A + LR+ ++ I++N NP T+ TD + A+R Y +
Sbjct: 101 IMILGAGPIVIGQACEFDYSGTQACKALREEGYEVILINSNPATIMTDPETANRTYIAPM 160
Query: 1040 NLERIMDIYELESSAGVVVSMGGQTSNNIAM------SLHRENVKILGTSPEMIDSAENR 1093
E + + E E ++ +MGGQT+ N+A+ +L + V+++G I AE+R
Sbjct: 161 TPELVEQVIEKERPDALLPTMGGQTALNLAVALAESGALEKYGVELIGAKLGAIKKAEDR 220
Query: 1094 YKFSRMLDQIDVDQPAWKELTSMDEAEDFAEKV-SYPVLVRPSYVLSGAAMNTVYSKDDL 1152
F + I + P T++DE D AEK+ +P+++RP++ L G Y+K++
Sbjct: 221 ELFKDAMKNIGLKTPPSGIGTTLDECFDIAEKIGEFPLIIRPAFTLGGTGGGIAYNKEEF 280
Query: 1153 ESYLNQAVEVSREYPVVITKYIENAKEIEMDAVA-LDGELIMHVVSEHVENAGVHSGDAT 1211
ES + S V++ K + KE E++ + L +++ E+++ GVH+GD+
Sbjct: 281 ESICKSGLAASATSQVLVEKSLLGWKEYELEVMRDLADNVVIICSIENIDPMGVHTGDSI 340
Query: 1212 LIVPPQDLDPETVRRIVEATAKIGRALQI-TGPYNIQFIAK--NNEIKVIECNVRASRSF 1268
+ P Q L +R+ + + I R + + G N+QF + E+ +IE N R SRS
Sbjct: 341 TVAPAQTLTDREYQRLRDYSIAIIREIGVECGGSNVQFAVNPVDGEVMIIEMNPRVSRSS 400
Query: 1269 PFISKVVGVNLIEMATKAIMGIPVTPYPVEKLPDD 1303
SK G + +MA K +G Y ++++P+D
Sbjct: 401 ALASKATGFPIAKMAAKLSVG-----YTLDQIPND 430
Score = 156 bits (394), Expect = 4e-37
Identities = 108/368 (29%), Positives = 170/368 (45%), Gaps = 24/368 (6%)
Query: 467 KEEGIYTILINPNIATIQTSKGLADKVYFLPVTAEFVRKVILHERPDAIYVTFGGQTALS 526
K+ G TI++N N T+ T +D++YF P+T E V VI E+PD I V FGGQT L
Sbjct: 449 KDAGYETIMLNSNPETVSTDYDTSDRLYFEPLTIEDVLNVIDLEKPDGIIVQFGGQTPLK 508
Query: 527 VGIEMK---DEFETLG------VKVLGTPIDTVITTEDRELFANAMDEINXXXXXXXXXX 577
+ + +K D+ + V++ GT D++ EDRE F +DE+
Sbjct: 509 LALPIKHYLDKHMPMSLSGAGPVRIWGTSPDSIDAAEDRERFNAILDELKIEQPKGGIAK 568
Query: 578 XXXXXXXXXXDIGFPVIVRAAYALGGLGSGFASNEKELVDLCNVAFASSPQ--VLVERSM 635
++G+PV+VR +Y LGG ++ L+ A P+ VLV++ +
Sbjct: 569 SEADALAIAKEVGYPVVVRPSYVLGGRAMEIVYDDSRLITYLENAVQVDPERPVLVDKYL 628
Query: 636 KGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVIAPSQTLSDEDYNMLRTTAVN 695
EI+ + + D++ N + ME+ + G+H+GDS + P+QT+ +RT
Sbjct: 629 SDAIEIDVDTLTDSYGNVVIGGIMEHIEQAGVHSGDSACMLPTQTIPASCLQTIRTWTTK 688
Query: 696 VIRHLGVVGECNIQYALNPTSKEYCIIEVNXXXXXXXXXXXXXTGYPLAYTAAKLGLNIP 755
+ + L V G N QYA+ TS + ++E N G+PLA AA +
Sbjct: 689 LAKKLNVCGLMNCQYAIT-TSGDVFLLEANPRASRTVPFVSKAIGHPLAKYAALVMSGKS 747
Query: 756 LYEVKNSVTRSTCACFEPSL--DYCVVKMPRWDLKKFTRVSTLLSSSMKSVGEVMSIGRT 813
L ++ FE + + VK + +KF +L M+S GEVMSI
Sbjct: 748 LKDLN----------FEKEVIPKHVSVKEAVFPFEKFQGCDVILGPEMRSTGEVMSISSE 797
Query: 814 FEEAIQKA 821
F A A
Sbjct: 798 FSSAFAMA 805
>At3g20330 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 390
Score = 241 bits (614), Expect = 1e-62
Identities = 134/312 (42%), Positives = 200/312 (63%), Gaps = 5/312 (1%)
Query: 1917 RTKNPFLRRNILSVNQFKRSDFHALFAVAQELRAGVEREGVLDVMKSRVLTTMFYEPSTR 1976
R F +++ QF R A+F VA+E+ + +++K ++ T+FYEPSTR
Sbjct: 77 RELKKFELSDVIEGKQFDREMLSAIFDVAREMEKIEKSSSQSEILKGYLMATLFYEPSTR 136
Query: 1977 TSSSFIAAMERLGGRTVNINTSA--SSVKKGETLQDTIRTLACYSDAIVLRHPDEMSAHI 2034
T SF +AM+RLGG + + SS KGETL+DTIRT+ YSD IV+RH + +A
Sbjct: 137 TRLSFESAMKRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSDIIVMRHFESGAARK 196
Query: 2035 AAKYSPVPIINGGNGSREHPTQAFLDLFTIREELGTVNGITVTFMGDLKFGRPVHSLCRL 2094
AA + +P+IN G+G EHPTQA LD++TI+ E+G ++GI+V +GDL GR V SL L
Sbjct: 197 AAATANIPVINAGDGPGEHPTQALLDVYTIQSEIGKLDGISVALVGDLANGRTVRSLAYL 256
Query: 2095 LQHYQ-VRINLIAPKELRLPNALRKELQDSGLLGIESETLTPEIISKSDVLYCTRVQQER 2153
L ++ V+I ++P+ +++ + ++ L SG+ ES L E+ SK DV+Y TR+Q+ER
Sbjct: 257 LAKFKDVKIYFVSPEIVKMKDDIKDYLTSSGVEWEESSDLM-EVASKCDVVYQTRIQRER 315
Query: 2154 FETEED-YLKLKDTYIVDNKILSHAKQQMVVMHPLPRVNEIREEVDYDHRAAYFRQMRYG 2212
F D Y + YIVD +L +++ ++MHPLPR++EI +VD D RAAYFRQ + G
Sbjct: 316 FGERLDLYEAARGKYIVDKDLLGVMQKKAIIMHPLPRLDEITADVDADPRAAYFRQAKNG 375
Query: 2213 LFVRMALLAMVM 2224
LF+RMALL +++
Sbjct: 376 LFIRMALLKLLL 387
>At3g27740 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 428
Score = 234 bits (596), Expect = 2e-60
Identities = 143/394 (36%), Positives = 218/394 (55%), Gaps = 30/394 (7%)
Query: 24 LELKDGTTLQGYSFGAETTAAGELVFQTGMVGYPESITDPSYEGQILVITFPLVGNYGV- 82
L L+DG+ SFGA T ELVF T + GY E +TDPSY GQ +++T P +GN GV
Sbjct: 58 LVLEDGSIWPAKSFGAPGTRIAELVFNTSLTGYQEILTDPSYAGQFVLMTNPQIGNTGVN 117
Query: 83 PDRKLMDEYVEGLPRYFESNRIHVAGLVIAHYTEEYSHWLAQSSLGTWLKESNVPAVYGI 142
PD DE ES + + GLVI + + S+W +L +L E ++ VY +
Sbjct: 118 PD----DE---------ESGQCFLTGLVIRNLSISTSNWRCTKTLADYLTERDIMGVYDL 164
Query: 143 DSRSLTKHLREAGSMLGRFALQKPGTSFEDANSAEWMSYFETPEWVDPNVDNLVAKVSLK 202
D+R++T+ LRE GS++G + ++ T E + W +D L++ VS K
Sbjct: 165 DTRAITRRLREDGSLIGVLSTEQSKTDDELLQMSR--------SWDIVGID-LISDVSCK 215
Query: 203 APKLFVPN-HPDIDL-VQGPDGKTLRIVAVDVGMKYNQIRCFVKRGVELLVVPWDY---D 257
+P +V + + D DGK+ +++A D G+K N +R G ++ VVP + +
Sbjct: 216 SPYEWVDKTNAEWDFNTNSRDGKSYKVIAYDFGIKQNILRRLSSYGCQITVVPSTFPAAE 275
Query: 258 FTTEEYDGLFISNGPGNPAILQEVSDRLTKVLDAKKTPVFGICLGHQLLARASGASTLKM 317
DG+ SNGPG+P+ + + + ++L K PV+GIC+GHQLL +A G T KM
Sbjct: 276 ALKMNPDGILFSNGPGDPSAVPYAVETVKELLG--KVPVYGICMGHQLLGQALGGKTFKM 333
Query: 318 KFGNRGHNIPCTSTVSGRCYITSQNHGFAVDETSLTNGWKSLFTNANDGSNEGIYHSELP 377
KFG+ G N P + +G+ I++QNH +AVD SL G + N NDGS G+ E+
Sbjct: 334 KFGHHGGNHPVRNNRTGQVEISAQNHNYAVDPASLPGGVEVTHVNLNDGSCAGLSFPEMN 393
Query: 378 YFSVQFHPESTPGPRDTEFLFDVFIQSVLDFKQT 411
S+Q+HPE++PGP D++ F FI+ + KQ+
Sbjct: 394 VMSLQYHPEASPGPHDSDNAFREFIELMKRSKQS 427
>At1g75330 [E] KOG1504 Ornithine carbamoyltransferase OTC/ARG3
Length = 375
Score = 85.9 bits (211), Expect = 7e-16
Identities = 95/389 (24%), Positives = 158/389 (40%), Gaps = 21/389 (5%)
Query: 1842 AVAKETPLAAVGTPILGAISTSRKRFSFSNERRLSINSMDGDDEEAILDQPLEQRLMSSR 1901
A A + ++ +P L S+S F + RR S S L P RL S
Sbjct: 2 AAAMASHVSTARSPALSFSSSSSSFFPGTTLRRFSAVS---------LPSPALPRLRVSC 52
Query: 1902 PPKELSAPSVLINLIRTKNPFLRRNILSVNQFKRSDFHALFAVAQELRAGVEREGVLDVM 1961
+++PS ++ K ++ L+++ F + + A E++A + + G + +
Sbjct: 53 QASSVTSPSSPSDV---KGKSDLKDFLAIDDFDTATIKTILDKASEVKA-LLKSGERNYL 108
Query: 1962 --KSRVLTTMFYEPSTRTSSSFIAAMERLGGRTVNINTSASSVKKGETLQDTIRTLACYS 2019
K + ++ +F +PS RT SF LGG + + + + K E +D R L+ Y+
Sbjct: 109 PFKGKSMSMIFAKPSMRTRVSFETGFFLLGGHALYLGPNDIQMGKREETRDVARVLSRYN 168
Query: 2020 DAIVLRHPDEMSAHIAAKYSPVPIINGGNGSREHPTQAFLDLFTIREELGTVNGITVTFM 2079
D I+ R A YS VP++NG HP Q D T+ E +G V G V ++
Sbjct: 169 DIIMARVFAHQDILDLANYSSVPVVNGLT-DHNHPCQIMADALTMIEHIGQVEGTKVVYV 227
Query: 2080 GDLKFGRPVHSLCRLLQHYQVRINLIAPKELRLPNALRKELQDSGLLGIESETLTPEIIS 2139
GD VHS L PK + + +GL IE E +
Sbjct: 228 GD--GNNMVHSWLELASVIPFHFVCACPKGYEPDKERVSKAKQAGLSKIEITNDPKEAVI 285
Query: 2140 KSDVLYC-TRVQQERFETEEDYLKLKDTYIVDNKILSHAKQQMVVMHPLP--RVNEIREE 2196
+DV+Y + + E K + VD ++ A Q+ MH LP R E+
Sbjct: 286 GADVVYSDVWASMGQKDEAEARRKAFQGFQVDEALMKLAGQKAYFMHCLPAERGVEVTNG 345
Query: 2197 VDYDHRAAYFRQMRYGLFVRMALLAMVMG 2225
V + F Q + + A++ ++G
Sbjct: 346 VVEAPYSIVFPQAENRMHAQNAIMLHLLG 374
>Hs9257234 [E] KOG1504 Ornithine carbamoyltransferase OTC/ARG3
Length = 354
Score = 78.2 bits (191), Expect = 1e-13
Identities = 70/306 (22%), Positives = 133/306 (42%), Gaps = 9/306 (2%)
Query: 1925 RNILSVNQFKRSDFHALFAVAQELRAGVEREG-VLDVMKSRVLTTMFYEPSTRTSSSFIA 1983
R++L++ F + + ++ +L+ ++++G L +++ + L +F + STRT S
Sbjct: 40 RDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTET 99
Query: 1984 AMERLGGRTVNINTSASSVKKGETLQDTIRTLACYSDAIVLRHPDEMSAHIAAKYSPVPI 2043
LGG T + E+L DT R L+ +DA++ R + AK + +PI
Sbjct: 100 GFALLGGHPCFPTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPI 159
Query: 2044 INGGNGSREHPTQAFLDLFTIREELGTVNGITVTFMGDLKFGRPVHSLCRLLQHYQVRIN 2103
IN G HP Q D T++E ++ G+T++ GD +HS+ + + +
Sbjct: 160 IN-GLSDLYHPIQILADYLTLQEHYSSLKGLTLSCFGD--GNNILHSIMMSAAKFGMHLQ 216
Query: 2104 LIAPKELRLPNALRKELQDSGLLGIESETLTPEIISKSD----VLYCTRVQQERFETEED 2159
PK ++ K + LT + + + ++ T + R E ++
Sbjct: 217 AATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGREEEKKK 276
Query: 2160 YLKLKDTYIVDNKILSHAKQQMVVMHPLPR-VNEIREEVDYDHRAAYFRQMRYGLFVRMA 2218
L+ Y V K A +H LPR E+ +EV Y R+ F + + MA
Sbjct: 277 RLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMA 336
Query: 2219 LLAMVM 2224
++ ++
Sbjct: 337 VMVSLL 342
>SPAC4G9.10 [E] KOG1504 Ornithine carbamoyltransferase OTC/ARG3
Length = 327
Score = 75.9 bits (185), Expect = 7e-13
Identities = 71/311 (22%), Positives = 137/311 (43%), Gaps = 14/311 (4%)
Query: 1925 RNILSVNQFKRSDFHALFAVAQELRAGVE------REGVLDVMKSRVLTTMFYEPSTRTS 1978
R++LS+ R + L + E++ + R + + S+ + +F + STRT
Sbjct: 8 RHLLSIRDLSRGEIVKLIDRSSEIKQAYKQNFQNRRSVQMSGLSSQNVAMIFSKRSTRTR 67
Query: 1979 SSFIAAMERLGGRTVNINTSASSVKKGETLQDTIRTLACYSDAIVLRHPDEMSAHIAAKY 2038
S +A+ LGG + + + E+L DT + ++ IV R AK+
Sbjct: 68 VSVESAVSCLGGNAMFLGKDDIQLGVNESLYDTSKVISSMVSGIVARVNKYSDVATLAKH 127
Query: 2039 SPVPIINGGNGSREHPTQAFLDLFTIREELGTVNGITVTFMGDLKFGRPVHSLCRLLQHY 2098
+ P+IN G HP QA DL TI+E + +G+ V ++GD +H L
Sbjct: 128 ASCPVIN-GLCDTFHPLQALADLLTIKETFKSFDGLKVAWVGDA--NNVLHDLMIANAKV 184
Query: 2099 QVRINLIAPKELRLPNALRKELQDSGLLGIESETLT--PEIISKSD--VLYCTRVQQERF 2154
+ ++ PK++ + + + + ++ + + P++ K+ V+ T + +
Sbjct: 185 GIHTSVAKPKDVNVRDDILSIVNEAANENGSTFEIVNDPKVAVKNADIVVTDTWISMGQE 244
Query: 2155 ETEEDYLKLKDTYIVDNKILSHAKQQMVVMHPLPR-VNEIREEVDYDHRAAYFRQMRYGL 2213
+E LK + V +I+ AK MH LPR E+ +EV Y + F++
Sbjct: 245 AEKEQRLKQFTGFQVTGEIMKLAKPSCKFMHCLPRHPEEVSDEVFYGENSLVFQEAENRK 304
Query: 2214 FVRMALLAMVM 2224
+ +A+L ++
Sbjct: 305 WTTVAVLEALL 315
>YBR208c_2 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 1200
Score = 66.2 bits (160), Expect = 6e-10
Identities = 65/300 (21%), Positives = 138/300 (45%), Gaps = 21/300 (7%)
Query: 1000 AVTAVRTLRKNNFKTIMVNYNPETVS---TDYDEADRLYFET-----INLERIMDIYELE 1051
AV ++TL+K +++ V +P+ S TD D + L+ T +++ +I+D +
Sbjct: 10 AVRIIKTLKKLGIRSVAVYSDPDKYSQHVTDADVSVPLHGTTAAQTYLDMNKIIDAAKQT 69
Query: 1052 SSAGVVVSMGGQTSN-NIAMSLHRENVKILGTSPEMIDSAENRYKFSRMLDQIDVDQ-PA 1109
++ ++ G + N + + + + +G S ++I ++ ++ + V P
Sbjct: 70 NAQAIIPGYGFLSENADFSDACTSAGITFVGPSGDIIRGLGLKHSARQIAQKAGVPLVPG 129
Query: 1110 WKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDL----ESYLNQAVEVSRE 1165
+TS++EA+ A ++ YPV+V+ + G + V S++D+ E+ +Q +
Sbjct: 130 SLLITSVEEAKKVAAELEYPVMVKSTAGGGGIGLQKVDSEEDIEHIFETVKHQGETFFGD 189
Query: 1166 YPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLI--VPPQDLDPET 1223
V + ++IENA+ +E V L G+ ++ + + + +I P +L +T
Sbjct: 190 AGVFLERFIENARHVE---VQLMGDGFGKAIALGERDCSLQRRNQKVIEETPAPNLPEKT 246
Query: 1224 VRRIVEATAKIGRALQITGPYNIQFI--AKNNEIKVIECNVRASRSFPFISKVVGVNLIE 1281
+ +A +G L ++FI K +E +E N R P V G++L+E
Sbjct: 247 RLALRKAAESLGSLLNYKCAGTVEFIYDEKKDEFYFLEVNTRLQVEHPITEMVTGLDLVE 306
>Hs4557833 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 703
Score = 58.5 bits (140), Expect = 1e-07
Identities = 59/311 (18%), Positives = 129/311 (40%), Gaps = 21/311 (6%)
Query: 1000 AVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYF--------ETINLERIMDIYELE 1051
A +RT +K KT+ ++ + + S AD +N++ IM+ +
Sbjct: 50 ACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKT 109
Query: 1052 SSAGVVVSMGGQTSNN-IAMSLHRENVKILGTSPEMIDSAENRYKFSRMLDQIDVDQ-PA 1109
+ V G + N A L E+V +G I + ++ + + + +V+ P
Sbjct: 110 RAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPG 169
Query: 1110 WKELTS-MDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVY----SKDDLESYLNQAVEVSR 1164
+ + +EA A ++ YPV+++ S G M + ++D +A
Sbjct: 170 FDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFG 229
Query: 1165 EYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLI--VPPQDLDPE 1222
+ ++I K+I+N + IE+ + G+ + + + + + ++ P LD E
Sbjct: 230 DDRLLIEKFIDNPRHIEIQVL---GDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAE 286
Query: 1223 TVRRIVEATAKIGRALQITGPYNIQFIAKNNE-IKVIECNVRASRSFPFISKVVGVNLIE 1281
T R + E + RA++ + ++F+ + + +E N R P + G++L++
Sbjct: 287 TRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQ 346
Query: 1282 MATKAIMGIPV 1292
+ G P+
Sbjct: 347 EMIRVAKGYPL 357
>SPBC17G9.11c [C] KOG0369 Pyruvate carboxylase
Length = 1185
Score = 55.8 bits (133), Expect = 8e-07
Identities = 63/303 (20%), Positives = 128/303 (41%), Gaps = 26/303 (8%)
Query: 1000 AVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLY-----------FETINLERIMDIY 1048
A+ RT + + T+ + + +S +AD Y + ++ I+ I
Sbjct: 45 AIRVFRTAHELSMHTVAIYSYEDRLSMHRQKADESYPIGKVGQYSPVGAYLAIDEIVSIA 104
Query: 1049 ELESSAGVVVSMGGQTSNN--IAMSLHRENVKILGTSPEMIDSAENRYKFSRMLDQ--ID 1104
+ + A +V G S N A ++ ++ +G SPE+IDS ++ K + + +
Sbjct: 105 K-RTGANLVHPGYGFLSENAEFARKVNEAGMQFVGPSPEVIDSLGDKTKARAIAIRCGVP 163
Query: 1105 VDQPAWKELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDL----ESYLNQAV 1160
V + +EAE F ++ PV+++ + G M V S D L E ++A+
Sbjct: 164 VVPGTPGPVEHYEEAEAFVKEYGLPVIIKAAMGGGGRGMRVVRSADTLKESFERARSEAL 223
Query: 1161 EVSREYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATL--IVPPQD 1218
+ V I ++++ K IE+ +A ++H+ H + V + I P +D
Sbjct: 224 ASFGDGTVFIERFLDKPKHIEIQLMADKAGNVIHL---HERDCSVQRRHQKVVEIAPAKD 280
Query: 1219 LDPETVRRIVEATAKIGRALQITGPYNIQFIA-KNNEIKVIECNVRASRSFPFISKVVGV 1277
LDP+ + + + KI + ++ +F+ + IE N R ++ GV
Sbjct: 281 LDPKIRQALYDDAIKIAKEVKYCNAGTAEFLLDQKGRHYFIEINPRIQVEHTITEEITGV 340
Query: 1278 NLI 1280
+++
Sbjct: 341 DIV 343
>Hs4505627 [C] KOG0369 Pyruvate carboxylase
Length = 1178
Score = 54.3 bits (129), Expect = 2e-06
Identities = 58/298 (19%), Positives = 119/298 (39%), Gaps = 18/298 (6%)
Query: 1000 AVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYFETINLE------RIMDIYEL--E 1051
A+ R + +T+ + +T +AD Y L I DI ++ E
Sbjct: 49 AIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKE 108
Query: 1052 SSAGVVVSMGGQTSN--NIAMSLHRENVKILGTSPEMIDSAENRYKFSRMLDQIDVDQPA 1109
++ V G S + A + V+ +G SPE++ ++ + + V
Sbjct: 109 NNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVP 168
Query: 1110 WKE--LTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLES----YLNQAVEVS 1163
+ +TS+ EA +F+ +P++ + +Y G M V+S ++LE ++A+
Sbjct: 169 GTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAF 228
Query: 1164 REYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLIVPPQDLDPET 1223
+ + K+IE + IE+ + I+H+ H I P LDP+
Sbjct: 229 GNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQ-KVVEIAPAAHLDPQL 287
Query: 1224 VRRIVEATAKIGRALQITGPYNIQFIA-KNNEIKVIECNVRASRSFPFISKVVGVNLI 1280
R+ + K+ + + ++F+ ++ + IE N R ++ V+L+
Sbjct: 288 RTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLV 345
>At1g03090 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 734
Score = 54.3 bits (129), Expect = 2e-06
Identities = 42/185 (22%), Positives = 84/185 (44%), Gaps = 11/185 (5%)
Query: 1116 MDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYS-KDDLESYLNQAVEVSREY---PVVIT 1171
+D + AEK+ YP++++P++ G M V S KD +S+L E + + +++
Sbjct: 177 IDHMKSEAEKIGYPIIIKPTHGGGGKGMRIVQSGKDFADSFLGAQREAAASFGVNTILLE 236
Query: 1172 KYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLI--VPPQDLDPETVRRIVE 1229
KYI + IE V + G+ +V+ + + V +I P ++ + + +
Sbjct: 237 KYITRPRHIE---VQIFGDKHGNVLHLYERDCSVQRRHQKIIEEAPAPNISEKFRANLGQ 293
Query: 1230 ATAKIGRALQITGPYNIQFI--AKNNEIKVIECNVRASRSFPFISKVVGVNLIEMATKAI 1287
A RA+ ++FI ++++ +E N R P +VG +L+E +
Sbjct: 294 AAVSAARAVGYYNAGTVEFIVDTESDQFYFMEMNTRLQVEHPVTEMIVGQDLVEWQIRVA 353
Query: 1288 MGIPV 1292
G P+
Sbjct: 354 NGEPL 358
>YMR207c [I] KOG0368 Acetyl-CoA carboxylase
Length = 2123
Score = 53.1 bits (126), Expect = 5e-06
Identities = 40/190 (21%), Positives = 84/190 (44%), Gaps = 21/190 (11%)
Query: 1114 TSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLESYLNQAVEVSREYPVVITKY 1173
+S ++A + A+ + +PV+++ S G + V ++DD + QAV + P+ + K
Sbjct: 159 SSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKV 218
Query: 1174 IENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATL---------IVPPQDLDPETV 1224
+ +A+ +E+ +A ++ N + D ++ P PET
Sbjct: 219 VTDARHLEVQLLA----------DQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETF 268
Query: 1225 RRIVEATAKIGRALQITGPYNIQFI--AKNNEIKVIECNVRASRSFPFISKVVGVNLIEM 1282
+R+ A ++G + ++++ K+++ +E N R P + GVNL
Sbjct: 269 QRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPAT 328
Query: 1283 ATKAIMGIPV 1292
+ MGIP+
Sbjct: 329 QLQIAMGIPM 338
>7303838 [C] KOG0369 Pyruvate carboxylase
Length = 1181
Score = 53.1 bits (126), Expect = 5e-06
Identities = 64/322 (19%), Positives = 128/322 (38%), Gaps = 24/322 (7%)
Query: 1000 AVTAVRTLRKNNFKTIMVNYNPETVSTDYDEADRLYFETINL---ERIMDIYEL-----E 1051
A+ R + K++ V + + +AD Y L E ++I EL E
Sbjct: 51 AIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKGLPPVEAYLNIPELIRVCKE 110
Query: 1052 SSAGVVVSMGGQTS--NNIAMSLHRENVKILGTSPEMIDSAENRYKFSRMLDQIDVDQPA 1109
+ V G S ++ A ++ ++ +G SPE++ + K + + I+ P
Sbjct: 111 NDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGD--KVAARVAAIEAGVPI 168
Query: 1110 WK----ELTSMDEAEDFAEKVSYPVLVRPSYVLSGAAMNTVYSKDDLESYLNQAVEVSR- 1164
+T+ +EA +F +K PV+ + +Y G M V +D+E +A ++
Sbjct: 169 VPGTDGPVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESFQRASSEAKA 228
Query: 1165 ---EYPVVITKYIENAKEIEMDAVALDGELIMHVVSEHVENAGVHSGDATLIVPPQDLDP 1221
+ I K+IE + IE+ + ++H+ H I P L
Sbjct: 229 AFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQ-KVVEIAPAPRLPI 287
Query: 1222 ETVRRIVEATAKIGRALQITGPYNIQFIA-KNNEIKVIECNVRASRSFPFISKVVGVNLI 1280
E ++ EA ++ R + ++F+ ++ IE N R ++ G++L+
Sbjct: 288 EIRDKMTEAAVRLARHVGYENAGTVEFLCDESGNFYFIEVNARLQVEHTVTEEITGIDLV 347
Query: 1281 EMATKAIMG--IPVTPYPVEKL 1300
+ + G +P Y +K+
Sbjct: 348 QSQIRVAEGMTLPELGYTQDKI 369
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126,213,880
Number of Sequences: 60738
Number of extensions: 5478743
Number of successful extensions: 14051
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 13768
Number of HSP's gapped (non-prelim): 55
length of query: 2228
length of database: 30,389,216
effective HSP length: 122
effective length of query: 2106
effective length of database: 22,979,180
effective search space: 48394153080
effective search space used: 48394153080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)