ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4051 suspect: LH KTDL KOG2043 Cell cycle control, cell division, chromosome partitioning Signaling protein SWIFT and related BRCT domain proteins
r_klactV4051 suspect: LH KTDL KOG2043 Replication, recombination and repair Signaling protein SWIFT and related BRCT domain proteins
r_klactV4051 suspect: LH KTDL KOG2043 Signal transduction mechanisms Signaling protein SWIFT and related BRCT domain proteins
r_klactV4051 suspect: LH KTDL KOG2043 Transcription Signaling protein SWIFT and related BRCT domain proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4051 1400625 1397953 -891
(891 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR154w [KTDL] KOG2043 Signaling protein SWIFT and related BRCT ... 233 1e-60
SPBC582.05c [KTDL] KOG2043 Signaling protein SWIFT and related B... 83 2e-15
>YHR154w [KTDL] KOG2043 Signaling protein SWIFT and related BRCT domain
proteins
Length = 1070
Score = 233 bits (594), Expect = 1e-60
Identities = 183/638 (28%), Positives = 292/638 (45%), Gaps = 78/638 (12%)
Query: 1 MSESSIFSNLRILVVKSSELSKDALDDIINTTKKNGALECVVYDLSQDETNNTSYVDKGQ 60
MS S +F L L++ ++E N C +Y+L + + DK
Sbjct: 1 MSTSLLFEQLNFLILVAAEAELPIAHSTRKLLMDNSCNNCQIYELYNENLKDVK-TDKDW 59
Query: 61 FLSQFSEQ-IHCIISKSIDFSFYRTAAFDFLIPVVDPKWIDHCLQFKRLMRTTCYSPDPM 119
F+++F Q +H +IS +I+F FY+ FD LIPVV W+ ++ KR +RT YSP+P
Sbjct: 60 FMNKFGPQTVHFVISNTINFPFYKIVYFDLLIPVVSHTWVQDSVKTKRHLRTNMYSPNPF 119
Query: 120 HFLKDCYIYVSKHSLNVVEYQLYCAIVSVFGGTCMDYLSTKATHIITWDKNDVAIKAMQK 179
H L+DC +Y+SK S N EY LY ++ + GGT ++Y+S + TH+I D I + K
Sbjct: 120 HLLRDCQVYISKSSFNKCEYILYSDLLHLLGGTLVNYISNRTTHVIVQSPQDPIIATVSK 179
Query: 180 F----------HKYTV------IYLMPNWLVDCLCGLEYIK-EDEYLINVNEDDLALKEK 222
+K+T ++ P W++ + +K E L ++ D + ++
Sbjct: 180 LTFGSFSSSSTNKHTEKPLREWKFVYPIWILYHFKMAKPLKGELATLCELDMQDTSEEQL 239
Query: 223 SQKLWDRTL----NSIDDWKVIPGFQLGKK--IILGDDLALPGTSYKFLLNWIKKCLGAQ 276
K W+ + S + P L K + DL Y FL +I+ L +
Sbjct: 240 FAK-WEEVIGDKQTSSSQLTLHPNKTLFKNHHFAISPDLNFFTPLYWFLKGFIED-LDGK 297
Query: 277 ITLVAGPSQLKK-----SQADLYIGYSANTEGVKNANECR--IVCANIPWLFYVWQMHKF 329
+T ++ LK D YIG+SAN+ ++ + I N+ WLFY++ + KF
Sbjct: 298 VTPLSFSDDLKSVYQAFPDIDCYIGHSANSPILEKTKSIKPEIHVGNVSWLFYMFALQKF 357
Query: 330 IH-PMXXXXXXXXXXXIFSNNELKATYTNYYGEQRYYIQLLVEALGGICSTELTKKNTHL 388
+F++ EL YTNY+G QR+YIQ LVE LGG+ + ELT+KNTHL
Sbjct: 358 TPVSQCKLIHQPFHAKLFTSKELTVAYTNYFGSQRFYIQRLVEILGGLSTPELTRKNTHL 417
Query: 389 ISPIASGKKFEXXXX-----XXXXXXXNHLWLEQCYKSGQKLDPQLEEFQQFPVNGGLSR 443
I+ GKKF+ NH+WLEQCY + KL+P+ FQ F ++ +
Sbjct: 418 ITKSTIGKKFKVAKKWSLDPQNAIIVTNHMWLEQCYMNNSKLNPKDSRFQNFKLDDNMGW 477
Query: 444 SLGQMSLMDHIE------------NQSDLDEKPSQEPPEEELRDSQQLNKEHPISMPTTP 491
++GQ+ MDH + + EKP PP + D N TP
Sbjct: 478 NIGQIG-MDHSSLPTPKNLSMVTYDTQSISEKP---PPTNDQMDQINDNTNVLSKKDGTP 533
Query: 492 ------AAEEHLTQTSKSSNHDVSLTNAPEDEQGDVTQVPKSSNNDTSLTKFP----KEL 541
+ +E + + K S +V++T++ + E+ V++ ++S FP K+
Sbjct: 534 ISSFENSIDEKIDKLQKISG-EVAVTHSGDLERSFVSRPSRAS--------FPVVDSKKS 584
Query: 542 QEEAKESTPVESPEMSVHQENGTIESKNDKGSIATPIT 579
+ K+S S E V E K ++ PIT
Sbjct: 585 NLQKKDSNSDISMETEVFCEG---HEKREEKEFTKPIT 619
Score = 200 bits (509), Expect = 7e-51
Identities = 141/464 (30%), Positives = 228/464 (48%), Gaps = 41/464 (8%)
Query: 447 QMSLMDHIENQSDLDEKPSQEPPEEELRDSQQLNKEHPISMPTTPAAEEHLTQTSKSSNH 506
+ + + ++D+D K +E E +++ Q+ +E T E +T++
Sbjct: 626 KQEIREQSRKKNDIDYKKEEEETELQVQLGQRTKREIK-----TSKKNEKEKETNECHIE 680
Query: 507 DVSLTNAPEDEQGD---VTQVPKSSNNDTSLTKFPKELQEEAKESTPVESPEMSVHQENG 563
+TN + E+ ++ +S DT KF + + + + +V+ +
Sbjct: 681 VDQMTNEKQGEESTGKLISTEDVTSKKDTD--KFSHLFEGLSDNDDHINDEKPAVNSKYT 738
Query: 564 TIE-SKNDKGSIATPITSRXXXXXXXXXXXXNPSQPLTPMSDTXXXXXXXXXXXLHEDIE 622
T + S+N + TP T++ +Q P S LH DIE
Sbjct: 739 TPKTSQNITSGVDTPTTAQ--------------TQVFMPSSGNSRLAKTQAAKRLHTDIE 784
Query: 623 SLNEFQKINKRKR--SPEL-LPEAIQEIKKQKALDSKADEMVSYLNISHKPYKIKAVLTN 679
SLNEFQK KRKR S E+ L + ++ K L +KA+++++ N Y +KAV T
Sbjct: 785 SLNEFQKNFKRKRIDSEEISLSQDVERSNNNKELATKAEKILARFN-ELPNYDLKAVCTG 843
Query: 680 C-HENLSNLDILILSKIGVIITPEIESFT--NTIIAPKKARTAXXXXXXXXXXXXYALTP 736
C H+ + +DI IL+++G+ I I+ N I APK RT +AL P
Sbjct: 844 CFHDGFNEVDIEILNQLGIKIFDNIKETDKLNCIFAPKILRTEKFLKSLSFEPLKFALKP 903
Query: 737 MFITNILTNINKEKP----VELEMSKYFIPDIDSKVLERTKLPTKVFARHGFTHVNISDD 792
FI ++L I+ +K + + + Y I I+ ++ +TKLPTKVF R +N+ +D
Sbjct: 904 EFIIDLLKQIHSKKDKLSQININLFDYEINGINESIISKTKLPTKVFERANIRCINLVND 963
Query: 793 IPGGYKLISSILKCHSMEEVNAI-GKKFQLEDLVENKSKKKSPN----YVLIASKASMAK 847
IPGG I S+LK H +E++N + KK ED++ N K+ YVLI +KAS K
Sbjct: 964 IPGGVDTIGSVLKAHGIEKINVLRSKKCTFEDIIPNDVSKQENGGIFKYVLIVTKASQVK 1023
Query: 848 KFNKCVKDADKNKKVFVVEWNWCVKSIFDLDINLEDHEYVIYNK 891
KF K + D DKN+ + +VEWNWCV+SIF L+++ + V+Y K
Sbjct: 1024 KFTKLINDRDKNETILIVEWNWCVESIFHLNVDFTSKKNVLYQK 1067
>SPBC582.05c [KTDL] KOG2043 Signaling protein SWIFT and related BRCT domain
proteins
Length = 878
Score = 83.2 bits (204), Expect = 2e-15
Identities = 106/469 (22%), Positives = 178/469 (37%), Gaps = 59/469 (12%)
Query: 98 WIDHCLQFKRLMRTTCYSPDPMHFLKDCYIYVSKHSLNVVEYQLYCAIVSVFGGTCMDYL 157
WI C+ L+ + YS +P K I S ++ + L + FGG L
Sbjct: 86 WIRDCVDKNTLLNYSFYSCNPYLLFKG--ICASSCQIDSYQSSLIDDALETFGGRFSKGL 143
Query: 158 STKATHIITWDKNDVAIKAMQKFHKYTVIYLMPNWLVDCLCGLEYIKEDEYLINVNEDDL 217
TH+ T+ K + ++ + P WL+DCL + I +D YL
Sbjct: 144 MKSMTHLFTYSGMGAKCKKVLDKPSLSIKLIHPQWLLDCLQFGQLIDQDPYL-------- 195
Query: 218 ALKEKSQKLWDRTLNSIDDWKVIPGFQLGKKIILGDDLALPGTSYKFLLNWIKKCLGAQI 277
S K D +++ + + GK+I +DL LP T+++ L +GA+I
Sbjct: 196 -FPNPSYKKNDSSISKAEPTSLFRNVLHGKRIYFSNDLNLP-TNFRHSLQKFSVGIGAKI 253
Query: 278 TLVAGPSQLKKSQADLYIGYSANTEGVKNANECRIVCANIPWLFYVWQMHKFIHPMXXXX 337
+ D++IG +T A+ I WL ++ + + P+
Sbjct: 254 A-------ESINDCDIFIGLKRDTIEFNLASNKNTTIGTISWLLNLFVLGSWKSPLLNAL 306
Query: 338 XXXXXXXIFSNNELKATYTNYYGEQRYYIQLLVEALGGICSTELTKKNTHLISPIASGKK 397
F +++ A TNY R Y++ L+ A G + +L NT LI+ + G+K
Sbjct: 307 HYPFPSVGFLKDQMVAV-TNYTDAARIYLEKLLLACGATYTKDLKPTNTLLIAASSYGQK 365
Query: 398 FEXXXXXXXXXXXNHLWLEQCYKSGQKLDPQLEEFQQFPV------------------NG 439
+ +H WL Y S + L Q F FPV G
Sbjct: 366 Y-GAAKVWNIPTVHHSWL---YSSFKNLSSQ--AFTDFPVPLDDSYMDFIFPCPLNVEKG 419
Query: 440 GLSRSLGQMSLMDHIENQSDLDEKPSQEPPEEELRDSQQLNKEHPISMPTTPAAEEHLTQ 499
+L + E D PS + + +++L KE T+ +H+
Sbjct: 420 SFEDTLKSSLTKGNSEVLLDDLSDPSVSSIKGN-KTNEELEKEF---KSTSDNFGKHIIL 475
Query: 500 TSKSSNH--DVSLTNAPEDEQGDVTQVPKSSNNDTSLTKFPKELQEEAK 546
TS SN D + A ED++ D +++T +ELQ+E +
Sbjct: 476 TSSFSNQSADKGSSLAAEDDRND---------EGSTITGVNRELQDEGR 515
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,314,218
Number of Sequences: 60738
Number of extensions: 2244381
Number of successful extensions: 8184
Number of sequences better than 1.0e-05: 2
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 8168
Number of HSP's gapped (non-prelim): 8
length of query: 891
length of database: 30,389,216
effective HSP length: 115
effective length of query: 776
effective length of database: 23,404,346
effective search space: 18161772496
effective search space used: 18161772496
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)