ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4069 normal R KOG0504 General function prediction only FOG: Ankyrin repeat
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4069 1402940 1406383 1148
(1148 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR233c_2 [R] KOG0504 FOG: Ankyrin repeat 399 e-110
YGR233c_1 [P] KOG1161 Protein involved in vacuolar polyphosphate... 288 4e-77
YGR233c_3 [R] KOG2421 Predicted starch-binding protein 226 1e-58
7304338 [M] KOG4177 Ankyrin 81 8e-15
Hs10190676_2 [R] KOG0504 FOG: Ankyrin repeat 80 2e-14
YPL110c_2 [R] KOG0504 FOG: Ankyrin repeat 78 7e-14
Hs7657238 [R] KOG0504 FOG: Ankyrin repeat 77 2e-13
Hs10947054 [M] KOG4177 Ankyrin 75 8e-13
Hs10947052 [M] KOG4177 Ankyrin 75 8e-13
At2g26660 [P] KOG1161 Protein involved in vacuolar polyphosphate... 75 8e-13
At5g20150 [P] KOG1161 Protein involved in vacuolar polyphosphate... 74 1e-12
SPAC6C3.08 [O] KOG4412 26S proteasome regulatory complex subunit... 74 1e-12
Hs4502093 [M] KOG4177 Ankyrin 74 2e-12
Hs10947056 [M] KOG4177 Ankyrin 74 2e-12
Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 73 2e-12
Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 73 2e-12
Hs10947042 [M] KOG4177 Ankyrin 72 4e-12
Hs10947040 [M] KOG4177 Ankyrin 72 4e-12
Hs10947038 [M] KOG4177 Ankyrin 72 4e-12
Hs10947036 [M] KOG4177 Ankyrin 72 4e-12
CE06705 [M] KOG4177 Ankyrin 72 7e-12
CE06704 [M] KOG4177 Ankyrin 72 7e-12
CE06703 [M] KOG4177 Ankyrin 72 7e-12
CE06702 [M] KOG4177 Ankyrin 72 7e-12
7301133 [T] KOG4369 RTK signaling protein MASK/UNC-44 71 9e-12
At5g15330 [P] KOG1161 Protein involved in vacuolar polyphosphate... 70 1e-11
7295892 [M] KOG4177 Ankyrin 70 2e-11
7293416 [U] KOG1162 Predicted small molecule transporter 69 6e-11
Hs19923272 [U] KOG1162 Predicted small molecule transporter 68 9e-11
Hs20538133 [R] KOG0504 FOG: Ankyrin repeat 67 1e-10
Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 67 2e-10
YPL110c_1 [U] KOG1162 Predicted small molecule transporter 66 3e-10
YGR232w [O] KOG4412 26S proteasome regulatory complex subunit PS... 66 4e-10
Hs7705831 [R] KOG0504 FOG: Ankyrin repeat 65 6e-10
Hs6601590 [R] KOG0510 Ankyrin repeat protein 65 6e-10
7301689 [R] KOG0504 FOG: Ankyrin repeat 64 1e-09
Hs22064845 [T] KOG0192 Tyrosine kinase specific for activated (G... 64 2e-09
Hs14731279 [R] KOG0504 FOG: Ankyrin repeat 64 2e-09
Hs4885087 [R] KOG0504 FOG: Ankyrin repeat 63 2e-09
Hs20472035 [R] KOG0504 FOG: Ankyrin repeat 63 2e-09
7290442 [U] KOG1162 Predicted small molecule transporter 63 2e-09
7298635 [U] KOG1162 Predicted small molecule transporter 63 3e-09
7295202 [M] KOG4177 Ankyrin 63 3e-09
Hs16159328 [R] KOG0504 FOG: Ankyrin repeat 62 4e-09
7295413 [U] KOG1162 Predicted small molecule transporter 62 7e-09
Hs13129098 [R] KOG0504 FOG: Ankyrin repeat 61 9e-09
At2g45130 [P] KOG1161 Protein involved in vacuolar polyphosphate... 61 9e-09
CE23926 [T] KOG4369 RTK signaling protein MASK/UNC-44 61 1e-08
CE06305 [T] KOG4369 RTK signaling protein MASK/UNC-44 61 1e-08
7301132 [R] KOG0504 FOG: Ankyrin repeat 60 2e-08
At4g22990_1 [P] KOG1161 Protein involved in vacuolar polyphospha... 60 3e-08
Hs13376003 [M] KOG4177 Ankyrin 59 3e-08
Hs4758818 [T] KOG1217 Fibrillins and related proteins containing... 59 4e-08
Hs18640738 [R] KOG0504 FOG: Ankyrin repeat 59 4e-08
Hs16076877 [R] KOG0504 FOG: Ankyrin repeat 59 4e-08
Hs13386462 [R] KOG0504 FOG: Ankyrin repeat 59 4e-08
Hs14738291 [R] KOG0504 FOG: Ankyrin repeat 59 6e-08
Hs18252778 [R] KOG0504 FOG: Ankyrin repeat 58 1e-07
CE07175 [R] KOG0508 Ankyrin repeat protein 58 1e-07
Hs4507613 [M] KOG4177 Ankyrin 57 1e-07
Hs22062923 [R] KOG0504 FOG: Ankyrin repeat 57 1e-07
7301359 [M] KOG4177 Ankyrin 57 1e-07
At4g11810_1 [P] KOG1161 Protein involved in vacuolar polyphospha... 57 1e-07
7297920 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 57 2e-07
YFL004w_1 [P] KOG1161 Protein involved in vacuolar polyphosphate... 57 2e-07
Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GT... 56 3e-07
Hs7705278_2 [R] KOG0504 FOG: Ankyrin repeat 56 3e-07
CE19142 [U] KOG1162 Predicted small molecule transporter 55 5e-07
Hs4557349_2 [R] KOG0504 FOG: Ankyrin repeat 55 6e-07
CE26238_1 [M] KOG4177 Ankyrin 55 6e-07
Hs20556512 [T] KOG0507 CASK-interacting adaptor protein (caskin)... 55 8e-07
7291279 [R] KOG0502 Integral membrane ankyrin-repeat protein Kid... 55 8e-07
Hs18079216 [T] KOG0507 CASK-interacting adaptor protein (caskin)... 54 1e-06
At5g02620 [R] KOG0504 FOG: Ankyrin repeat 54 1e-06
SPAPB1E7.05_1 [R] KOG0504 FOG: Ankyrin repeat 54 2e-06
Hs13376842 [M] KOG4177 Ankyrin 53 2e-06
CE05814 [R] KOG0502 Integral membrane ankyrin-repeat protein Kid... 53 2e-06
CE05333 [R] KOG0510 Ankyrin repeat protein 53 2e-06
Hs22060186 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger do... 53 3e-06
At5g54710 [R] KOG0504 FOG: Ankyrin repeat 53 3e-06
7294632_2 [R] KOG0504 FOG: Ankyrin repeat 53 3e-06
Hs13899329 [R] KOG0504 FOG: Ankyrin repeat 52 4e-06
CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 52 5e-06
At3g03790 [S] KOG1426 FOG: RCC1 domain 52 5e-06
7296936 [R] KOG0504 FOG: Ankyrin repeat 52 5e-06
7293339 [R] KOG0504 FOG: Ankyrin repeat 52 5e-06
SPAC2F7.10 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger do... 52 7e-06
Hs7706377 [R] KOG0504 FOG: Ankyrin repeat 52 7e-06
At2g26650 [PT] KOG0498 K+-channel ERG and related proteins conta... 52 7e-06
Hs4506217 [O] KOG4412 26S proteasome regulatory complex subunit ... 51 9e-06
Hs13375989 [R] KOG0504 FOG: Ankyrin repeat 51 9e-06
7294199_2 [R] KOG0504 FOG: Ankyrin repeat 51 9e-06
>YGR233c_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 477
Score = 399 bits (1025), Expect = e-110
Identities = 227/484 (46%), Positives = 303/484 (61%), Gaps = 68/484 (14%)
Query: 358 FWKYGNEYIDLTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAF 417
F+K ++IDL+Y D +DD VF+R N+FHEAA CP + R F+L AL S + +E
Sbjct: 1 FYKSNQDHIDLSYCD-EDDQVFSRKNVFHEAASCPEKSRLFILDEAL---TTSKLSKETV 56
Query: 418 RKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIE 477
+KLLNAQDIH R+PLHYA ELGK FV L+ T L++++D +D+ SKTPLVL+I NNHI+
Sbjct: 57 QKLLNAQDIHSRVPLHYAAELGKLEFVHSLLITNLLEDVDPIDSDSKTPLVLAITNNHID 116
Query: 478 VTKILIAQGNVNLSP----------SLCEGTKPQFHPLNVACSNKNYEAAKVILE---KG 524
V + L+ G N SP ++ TK QF PLNVAC N++AAK++LE K
Sbjct: 117 VVRDLLTIGGANASPIEKPILDYSKNVISSTKVQFDPLNVACKFNNHDAAKLLLEIRSKQ 176
Query: 525 DINLSRLRDSQ------------GLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKW 572
+ + ++ + SQ GLC LHIVAK+GG +LI+LL+ YGADP+EIDGFNKW
Sbjct: 177 NADNAKNKSSQHLCQPLFKKNSTGLCTLHIVAKIGGDPQLIQLLIRYGADPNEIDGFNKW 236
Query: 573 PPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKR 632
PIFYA++ GH+ + LL+ A + ++D S +FYALWE H+ VLN LL +R
Sbjct: 237 TPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYALWESHVDVLNALL------QR 290
Query: 633 YSAFPDRPLAGSLRPSDPGELF------SDDQLSLNDSLKDIPDFTLPPPIIPLRKYGHN 686
P PL S L +DD+ L D IPDF LPPPIIPLRKYGHN
Sbjct: 291 PLNLPSAPLNEINSQSSTQRLNTIDLTPNDDKFDL-DIQDSIPDFALPPPIIPLRKYGHN 349
Query: 687 FLERKIFVKLSFKPGKESITLNKDDE-MMLSSPGRITLTSSVSNIIPRNIILPI------ 739
FLE+KIF+KL +PG ESI L +D+ +M SSPGRITL+S++ IIPRN+ILP+
Sbjct: 350 FLEKKIFIKLKLRPGLESIKLTQDNGIIMSSSPGRITLSSNLPEIIPRNVILPVRSGEIN 409
Query: 740 -------------------QEEDEKDIVFQIDSLDTFDIDIEIYPSFGTRLIAKTYALSD 780
++ D+ +I+FQ+DS+D F +D EI+PSFGTR+IAKT A+
Sbjct: 410 NFCKDISETNDEEDDDEISEDHDDGEIIFQVDSIDDFSMDFEIFPSFGTRIIAKTTAMPF 469
Query: 781 VFHK 784
+F K
Sbjct: 470 LFKK 473
>YGR233c_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 357
Score = 288 bits (736), Expect = 4e-77
Identities = 155/365 (42%), Positives = 230/365 (62%), Gaps = 16/365 (4%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRY 60
MKFGK+LE RQLEL EYN HFI+YKALKKLIKQL++P + + ++ + ++TLD+ DE I +
Sbjct: 1 MKFGKYLEARQLELAEYNSHFIDYKALKKLIKQLAIPTLKASSDLDLHLTLDDIDEKIIH 60
Query: 61 QSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKGKLTSKKSIAY 120
Q LQENKA+FFFKLERELEKVN +YL +E+DLR+KF++L+S+Y +YK GKL S ++ ++
Sbjct: 61 QRLQENKAAFFFKLERELEKVNGYYLARESDLRIKFNILHSKYKDYKINGKLNSNQATSF 120
Query: 121 RTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSHAKDFYLATVVSVQPVFTR 180
+ + KKF++DL LEQ+VELN+TGFSK LKKWDKRS SH KDFYLATVVS+QP+FTR
Sbjct: 121 KNLYAAFKKFQKDLRNLEQYVELNKTGFSKALKKWDKRSQSHDKDFYLATVVSIQPIFTR 180
Query: 181 NEVSKWNDA---VXXXXXXXXXXXXXXXVTGPNFYGPAGQISRTISRNSESGPSMSNIIA 237
+ K ND + + F + T + N + + +N
Sbjct: 181 DGPLKLNDETLHILLELNDIDNNNRRADIQSSTFTNDDDDDNNTSNNNKHNNNNNNN--- 237
Query: 238 PKPETRTSVSSDKSTFLIN---FSQGXXXXXXXXXXXXXXXGLFDIELEIESWYMEVLSI 294
+ +++ + L N + D+E+EIE+WY E+L+I
Sbjct: 238 ----NNNNNNNNNNNILHNNYELTTSKISENQLEHLFQASSSSLDMEMEIENWYKEILNI 293
Query: 295 SKLKDVEPRKTHIRTFVETKVQSFVDSHLSATRIDKNL--VIRDSITKIFNLLLASSIDD 352
+ +KDV+ + +R F ETK+ +++ + S+ KN+ ++++ +T +F LL+AS +DD
Sbjct: 294 ATVKDVQRKHALLRNFRETKIFTYLLQN-SSESFHKNVFSLLKECLTTLFLLLVASPLDD 352
Query: 353 ESLEV 357
SL +
Sbjct: 353 NSLHI 357
>YGR233c_3 [R] KOG2421 Predicted starch-binding protein
Length = 344
Score = 226 bits (577), Expect = 1e-58
Identities = 137/348 (39%), Positives = 191/348 (54%), Gaps = 16/348 (4%)
Query: 795 LTLPLFDTRLRNVGKFDVDFEVIFPYGGKSLEVTKYETYWKXXXXXXXXXXXXXXXXXXQ 854
+ LPLFDTRL N+G +D+++IFPY G L++ YE YWK
Sbjct: 5 MNLPLFDTRLNNIGSLTLDYQIIFPYPGNPLKIINYEPYWKSTGSDLMTSSKDG------ 58
Query: 855 SIVTASSLNGKYCTIGVIQLNDGTLIASTSLICHAGDVPLLFNDMNAKQLNSMLDQQISD 914
+ VT+SSLNG + ++ V LND T++A+ +L ND+ +QL ++D
Sbjct: 59 NFVTSSSLNGSFISVLVCALNDETIVAAPKPYVEFKGTKILLNDLTKEQLEKVVDYDFGK 118
Query: 915 IPANITSRLTLKTLLRDRYVLFEDLLNNVDPQIQLNIKVLFPTESEIQSIPMKVSPRYNL 974
I + +TLK L R V LL + QL I+V FPT+ EI +IP+K+SP N+
Sbjct: 119 IDGSF-DEVTLKQYLSSRVVPLRSLLEVIPGSAQLVIRVYFPTDKEIDTIPIKISPFINI 177
Query: 975 NCFIETVLSTTFEHVRKLRQ--MGSTRSIVFSSTNPRVCSILNWKQPNFPVLFDM-NVIS 1031
N FI+ +L FEH R LR GS R IVFSS N CSILNWKQPNFPVL M N++
Sbjct: 178 NQFIDKLLLIIFEHERFLRHSGSGSMRQIVFSSCNWEACSILNWKQPNFPVLLQMKNLLR 237
Query: 1032 ENSDGDLVKITSNDLASMALDTKDIIYGDPGTMSIKDAVIFANNNNLLGMILPINLLDIT 1091
+++ G V T N L +A++ + + Y + ++I V FA NNNLLG+ LP +L I
Sbjct: 238 DSTTGKFVGDTPNCLKELAVNPQKMSYLNTELINIHTMVQFAMNNNLLGVTLPYEVLKIC 297
Query: 1092 LQLVDQVLGHGLFLIGSTNGTISEHEQ--RDLGINGIQYKEELVIHEN 1137
L + +GL LI S + E++Q D G +GI Y EL+ N
Sbjct: 298 PSLARIIKQNGLLLIAS----VGENDQIPADGGYSGIYYACELLFENN 341
>7304338 [M] KOG4177 Ankyrin
Length = 1526
Score = 81.3 bits (199), Expect = 8e-15
Identities = 66/242 (27%), Positives = 105/242 (43%), Gaps = 47/242 (19%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
NA G PLH AC+ GK N V +L+ +ID TPL ++ N+ + ++
Sbjct: 534 NAVTKKGFTPLHLACKYGKQNVVQILLQNGA--SIDFQGKNDVTPLHVATHYNNPSIVEL 591
Query: 482 LIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPL 540
L+ G+ SP+LC + +++AC E A +L+ G D+N+ G PL
Sbjct: 592 LLKNGS---SPNLC--ARNGQCAIHIACKKNYLEIAMQLLQHGADVNII---SKSGFSPL 643
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGA----- 595
H+ A+ GG ++++LL+ YG N P+ A QEGH Q+LLE GA
Sbjct: 644 HLAAQ-GGNVDMVQLLLEYGVISAAAK--NGLTPLHVAAQEGHVLVSQILLEHGANISER 700
Query: 596 ----------------------------DVFMKDQQNLSQVFYALWEGHLSVLNVLLSYA 627
D+ M + + A +GH+ ++N+LL +
Sbjct: 701 TRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHK 760
Query: 628 GN 629
N
Sbjct: 761 AN 762
Score = 62.8 bits (151), Expect = 3e-09
Identities = 55/201 (27%), Positives = 100/201 (49%), Gaps = 13/201 (6%)
Query: 427 HGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG 486
H PLH AC+ GK + +LL+ ID TPL + + H+EV K L+ Q
Sbjct: 243 HNITPLHVACKWGKLSLCTLLLCRGA--KIDAATRDGLTPLHCASRSGHVEVIKHLLQQN 300
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLSRLRDSQGLCPLHIVAK 545
+P L + TK L++A ++ EAA ++L+ K ++ + L LH+ A
Sbjct: 301 ----APILTK-TKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTV---DYLTALHVAAH 352
Query: 546 MGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNL 605
G ++ KLL+ Y A+P+ N + P+ A ++ V++L++ GA++ + L
Sbjct: 353 C-GHVKVAKLLLDYKANPN-ARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGL 410
Query: 606 SQVFYALWEGHLSVLNVLLSY 626
+ + A + G ++++ LL +
Sbjct: 411 TPLHVASFMGCINIVIYLLQH 431
Score = 61.2 bits (147), Expect = 9e-09
Identities = 61/252 (24%), Positives = 108/252 (42%), Gaps = 26/252 (10%)
Query: 373 PDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIHGRMPL 432
P D++ H AA C H +LL ++ NA+ ++G PL
Sbjct: 335 PVDEVTVDYLTALHVAAHCGHVKVAKLLLD--------------YKANPNARALNGFTPL 380
Query: 433 HYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLSP 492
H AC+ + V LLI NI + TPL ++ I + L+ P
Sbjct: 381 HIACKKNRIKMVELLIKHGA--NIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLP 438
Query: 493 SLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSEL 552
++ T PL++A + +++L ++ +G PLH+ +++G +
Sbjct: 439 TIRGET-----PLHLAARANQADIIRILLRSAKVDAIA---REGQTPLHVASRLGN-INI 489
Query: 553 IKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYAL 612
I LL+ +GA+ + +K+ + A +EG VQVLLE GA+ ++ + + A
Sbjct: 490 IMLLLQHGAEINAQSN-DKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLAC 548
Query: 613 WEGHLSVLNVLL 624
G +V+ +LL
Sbjct: 549 KYGKQNVVQILL 560
Score = 60.1 bits (144), Expect = 2e-08
Identities = 54/220 (24%), Positives = 97/220 (43%), Gaps = 18/220 (8%)
Query: 413 QQEAFRKLLNAQDI-----HGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPL 467
Q + R LL + + G+ PLH A LG N + LL+ I+ N + L
Sbjct: 454 QADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGA--EINAQSNDKYSAL 511
Query: 468 VLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DI 526
++ + ++L+ G N + TK F PL++AC +++L+ G I
Sbjct: 512 HIAAKEGQENIVQVLLENGAENNAV-----TKKGFTPLHLACKYGKQNVVQILLQNGASI 566
Query: 527 NLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATT 586
+ D + PLH+ S +++LL+ G+ P+ + N I A ++ +
Sbjct: 567 DFQGKND---VTPLHVATHYNNPS-IVELLLKNGSSPN-LCARNGQCAIHIACKKNYLEI 621
Query: 587 VQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
LL+ GADV + + S + A G++ ++ +LL Y
Sbjct: 622 AMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEY 661
Score = 54.7 bits (130), Expect = 8e-07
Identities = 63/255 (24%), Positives = 103/255 (39%), Gaps = 36/255 (14%)
Query: 397 TFVLLAALYQYQNSIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNI 456
T + +A+L + I Q + +N Q ++G PL+ A + N L+ N
Sbjct: 85 TALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGA--NP 142
Query: 457 DLLDNTSKTPLVLSIINNHIEVTKILI---AQGNVNL---------------------SP 492
L TPL +++ H ++ +L+ +G V L P
Sbjct: 143 SLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDP 202
Query: 493 SLCEGTKPQFHPLNVACSNKNYEAAKVIL-EKGDINLSRLRDSQGLCPLHIVAKMGGGSE 551
+ +K F PL++A N + A ++L K D+N + PLH+ K G S
Sbjct: 203 NADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVA---KHNITPLHVACKWGKLS- 258
Query: 552 LIKLLVSYGADPDEI--DGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVF 609
L LL+ GA D DG P+ A + GH ++ LL+ A + K + LS +
Sbjct: 259 LCTLLLCRGAKIDAATRDGLT---PLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALH 315
Query: 610 YALWEGHLSVLNVLL 624
A H ++LL
Sbjct: 316 MAAQGEHDEAAHLLL 330
Score = 52.0 bits (123), Expect = 5e-06
Identities = 57/213 (26%), Positives = 91/213 (41%), Gaps = 14/213 (6%)
Query: 420 LLNAQDIHG--RMP-LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHI 476
+L D+ G R+P LH A + N LL+ + N D++ + TPL ++ ++
Sbjct: 167 VLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHD--PNADIVSKSGFTPLHIAAHYGNV 224
Query: 477 EVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQG 536
++ +L+ N + K PL+VAC ++L +G + RD G
Sbjct: 225 DIATLLL-----NNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRD--G 277
Query: 537 LCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGAD 596
L PLH ++ G E+IK L+ A P N + A Q H +LL+ A
Sbjct: 278 LTPLHCASR-SGHVEVIKHLLQQNA-PILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAP 335
Query: 597 VFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
V L+ + A GH+ V +LL Y N
Sbjct: 336 VDEVTVDYLTALHVAAHCGHVKVAKLLLDYKAN 368
Score = 51.6 bits (122), Expect = 7e-06
Identities = 59/224 (26%), Positives = 93/224 (41%), Gaps = 36/224 (16%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G LH A G+ + ++ LI N+ L+ TPL ++ NH + L+A G
Sbjct: 83 GNTALHIASLAGQHDVINQLILYNANVNVQSLNGF--TPLYMAAQENHDNCCRTLLANG- 139
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-----------------KGDINLSR 530
+PSL T+ F PL VA + + V+LE K D+N ++
Sbjct: 140 --ANPSL--STEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAK 195
Query: 531 LR----------DSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQ 580
L G PLHI A G ++ LL++ AD + + N P+ A +
Sbjct: 196 LLLQHDPNADIVSKSGFTPLHIAAHY-GNVDIATLLLNNKADVNYVAKHN-ITPLHVACK 253
Query: 581 EGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLL 624
G + +LL GA + + L+ + A GH+ V+ LL
Sbjct: 254 WGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLL 297
>Hs10190676_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 280
Score = 80.1 bits (196), Expect = 2e-14
Identities = 58/208 (27%), Positives = 102/208 (48%), Gaps = 16/208 (7%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N D GR P+H AC+ G+ N V +L+ + ++ L + PL + H+ + K
Sbjct: 26 VNEVDFEGRTPMHVACQHGQENIVRILLRRGV--DVSLQGKDAWLPLHYAAWQGHLPIVK 83
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEK-GDINLSRLRDSQGLCP 539
+L Q V+++ +G PL++A +Y A+++++ D+N+ L P
Sbjct: 84 LLAKQPGVSVNAQTLDGRT----PLHLAAQRGHYRVARILIDLCSDVNVCSL---LAQTP 136
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEI--DGFNKWPPIFYAIQEGHATTVQVLLELGADV 597
LH+ A+ G S +LL+ GA + DG+ + A + GH TV++L+E ADV
Sbjct: 137 LHVAAETGHTS-TARLLLHRGAGKKAVTSDGYT---ALHLAARNGHLATVKLLVEEKADV 192
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVLLS 625
+ N + + A GH V+ L+S
Sbjct: 193 LARGPLNQTALHLAAAHGHSEVVEELVS 220
Score = 55.1 bits (131), Expect = 6e-07
Identities = 51/179 (28%), Positives = 88/179 (48%), Gaps = 16/179 (8%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NAQ + GR PLH A + G +LI +L ++++ ++TPL ++ H +
Sbjct: 93 VNAQTLDGRTPLHLAAQRGHYRVARILI--DLCSDVNVCSLLAQTPLHVAAETGHTSTAR 150
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
+L+ +G + T + L++A N + K+++E+ L+R +Q L
Sbjct: 151 LLLHRGAGKKAV-----TSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQ--TAL 203
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKW--PPIFYAIQEGHATTVQVLLELGADV 597
H+ A G SE+++ LVS D ID F++ + A Q HA TV+ LL GA +
Sbjct: 204 HLAAAHGH-SEVVEELVS----ADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHI 257
>YPL110c_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 519
Score = 78.2 bits (191), Expect = 7e-14
Identities = 94/386 (24%), Positives = 162/386 (41%), Gaps = 54/386 (13%)
Query: 418 RKLLNAQDIHGRMPLHYACELGKTNFVSLLI---------NTELIDNIDLL-DNTSKTPL 467
R L D + R PLHY+C+ G + L+I N ID++ D S TPL
Sbjct: 115 RPCLFQHDNYKRTPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPL 174
Query: 468 VLSIINNHIEVTKILI--AQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGD 525
L ++ H + T++L+ NV L S L++A NY V+L
Sbjct: 175 HLCVLGAHPKTTEVLLQSLDPNVKLKSSSL---------LHLATEWNNYPLLHVLLSSKR 225
Query: 526 INLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHAT 585
+++ + PL++ ++ + LL + GAD + + W IF A EG
Sbjct: 226 FDINYQDNELHETPLYLACRLNFFEAAVCLLYN-GADLEIREKLFGWTAIFVAAAEGFTD 284
Query: 586 TVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSL 645
V++L+ A+ ++D+ + + +A+ GHL + +++ R P L
Sbjct: 285 IVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMVQI----RDELVTHPHSQLNSGS 340
Query: 646 RPSDP-GELFSDDQLSLNDSLKDIPDFTLPPPIIPLRKYGHNFL---ERKIFVKLSFKPG 701
+P E+ + + N++ +L P++ YGH FL E I + L
Sbjct: 341 EEKEPLNEISAGELNERNENGNGGNKGSLGKLAGPIKSYGHRFLDNNESLILITLG---- 396
Query: 702 KESITLNKDDEMMLSSPG-----------RITLTSSVSNIIPR-NIILPIQEEDEKDIV- 748
+ T NK + LSS ++L S ++ I + ++IL + +D D V
Sbjct: 397 -SNDTRNKSPSISLSSEALAKVIGLETDCALSLVISCNDSIDKSSVILDLPLDDNVDAVD 455
Query: 749 ----FQIDSLDTFDIDIEIYPSFGTR 770
F++D T D I P++GTR
Sbjct: 456 FKVPFKVDYSHTLYFD--IVPTYGTR 479
>Hs7657238 [R] KOG0504 FOG: Ankyrin repeat
Length = 1065
Score = 77.0 bits (188), Expect = 2e-13
Identities = 68/248 (27%), Positives = 102/248 (40%), Gaps = 42/248 (16%)
Query: 411 IIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLS 470
I+ LLN QD GR PLH+A G V +L + E NI DN +TPL +
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWA 262
Query: 471 IINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-------- 522
+ H ++ +L+ + PS +G PL+ A + E KV L+
Sbjct: 263 ALLGHAQIVHLLLERNKSGTIPSDSQGAT----PLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 523 --------------------------KGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLL 556
K DI+++ + D G LH A + G +KLL
Sbjct: 319 DLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDIN-MADKYGGTALH-AAALSGHVSTVKLL 376
Query: 557 VSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGH 616
+ A D D K P+F A + GH +Q L++ GA V + DQ S + +A G+
Sbjct: 377 LENNAQVDATD-VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGN 435
Query: 617 LSVLNVLL 624
V +L+
Sbjct: 436 ADVCQILI 443
Score = 54.7 bits (130), Expect = 8e-07
Identities = 49/218 (22%), Positives = 103/218 (46%), Gaps = 18/218 (8%)
Query: 425 DIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIA 484
D+ GR +A G + + +++ + +I++ D T L + ++ H+ K+L+
Sbjct: 319 DLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLL- 377
Query: 485 QGNVNLSPSLCEGTKPQFH-PLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIV 543
+ N + + T H PL AC + + + ++ KG + L D G LH
Sbjct: 378 ENNAQV-----DATDVMKHTPLFRACEMGHKDVIQTLI-KGGARVD-LVDQDGHSLLHWA 430
Query: 544 AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQ 603
A +GG +++ ++L+ +P+ D + P+ A G+ + VL+E AD ++D++
Sbjct: 431 A-LGGNADVCQILIENKINPNVQDYAGR-TPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 604 NLSQVFYALWEGHLSVLNVLLSYA-------GNRKRYS 634
+ + ++ G+L + +LL +A N +RY+
Sbjct: 489 GRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
>Hs10947054 [M] KOG4177 Ankyrin
Length = 1872
Score = 74.7 bits (182), Expect = 8e-13
Identities = 68/253 (26%), Positives = 115/253 (44%), Gaps = 40/253 (15%)
Query: 420 LLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVT 479
L++A+ + PLH A LGKT V LL+ + + + D TPL +S ++V
Sbjct: 489 LVDARAREEQTPLHIASRLGKTEIVQLLL--QHMAHPDAATTNGYTPLHISAREGQVDVA 546
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEK-------GDINLSRLR 532
+L+ G + SL TK F PL+VA + + AK++L++ G L+ L
Sbjct: 547 SVLLEAGAAH---SL--ATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLH 601
Query: 533 -----DSQ-------------------GLCPLHIVAKMGGGSELIKLLVSYGADPDEIDG 568
D+Q G PLHI AK ++ L++YGA+ + +
Sbjct: 602 VAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK-NQMQIASTLLNYGAETNIVTK 660
Query: 569 FNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAG 628
P+ A QEGH V +LL+ GA++ M + L+ + A E ++V ++L +
Sbjct: 661 -QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGA 719
Query: 629 NRKRYSAFPDRPL 641
++ ++ PL
Sbjct: 720 DQDAHTKLGYTPL 732
Score = 74.3 bits (181), Expect = 1e-12
Identities = 66/257 (25%), Positives = 113/257 (43%), Gaps = 25/257 (9%)
Query: 368 LTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIH 427
L + P DD+ H AA C H T +LL R NA+ ++
Sbjct: 352 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK--------------RANPNARALN 397
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G PLH AC+ + + LL+ +I + + TP+ ++ H+ + +L+ G
Sbjct: 398 GFTPLHIACKKNRIKVMELLVKYGA--SIQAITESGLTPIHVAAFMGHLNIVLLLLQNG- 454
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMG 547
SP + L++A E + +L G + +R R+ Q PLHI +++
Sbjct: 455 --ASPDVTNIRGET--ALHMAARAGQVEVVRCLLRNGALVDARAREEQ--TPLHIASRL- 507
Query: 548 GGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQ 607
G +E+++LL+ + A PD N + P+ + +EG VLLE GA + ++ +
Sbjct: 508 GKTEIVQLLLQHMAHPDAAT-TNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTP 566
Query: 608 VFYALWEGHLSVLNVLL 624
+ A G L V +LL
Sbjct: 567 LHVAAKYGSLDVAKLLL 583
Score = 64.7 bits (156), Expect = 8e-10
Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 19/202 (9%)
Query: 427 HGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG 486
+G PLH A + G TN V LL++ ID TPL + + H +V ++L+ +G
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRG--GQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 322
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEK----GDINLSRLRDSQGLCPLHI 542
+P L TK PL++A + E K +L+ D+ L L LH+
Sbjct: 323 ----APLLAR-TKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDY------LTALHV 371
Query: 543 VAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQ 602
A G + KLL+ A+P+ N + P+ A ++ +++L++ GA + +
Sbjct: 372 AAHC-GHYRVTKLLLDKRANPN-ARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITE 429
Query: 603 QNLSQVFYALWEGHLSVLNVLL 624
L+ + A + GHL+++ +LL
Sbjct: 430 SGLTPIHVAAFMGHLNIVLLLL 451
Score = 60.5 bits (145), Expect = 2e-08
Identities = 62/232 (26%), Positives = 92/232 (38%), Gaps = 44/232 (18%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G LH A G+ V +L+ NI+ TPL ++ NHI+V K L+ G
Sbjct: 97 GNTALHIASLAGQAEVVKVLVKEGA--NINAQSQNGFTPLYMAAQENHIDVVKYLLENG- 153
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE---KGDINLSRLR------------ 532
N S + T+ F PL VA + +A ++LE KG + L L
Sbjct: 154 ANQSTA----TEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAA 209
Query: 533 --------------------DSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKW 572
G PLHI A G + LL++ GA D N
Sbjct: 210 LLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHY-GNVNVATLLLNRGAAVD-FTARNGI 267
Query: 573 PPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLL 624
P+ A + G+ V++LL+ G + K + L+ + A GH V+ +LL
Sbjct: 268 TPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL 319
Score = 58.2 bits (139), Expect = 8e-08
Identities = 53/209 (25%), Positives = 92/209 (43%), Gaps = 27/209 (12%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDL--------LDNTSKTPLVLSIINNHIEVT 479
G PL A + G V++L+ + + L D+T L+L +N +
Sbjct: 163 GFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQS 222
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
K+++ + T+ F PL++A N A ++L +G R+ G+ P
Sbjct: 223 KMMVNRT-----------TESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN--GITP 269
Query: 540 LHIVAKMGGGSELIKLLVSYGA--DPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADV 597
LH+ +K G + ++KLL+ G D DG P+ A + GH V++LLE GA +
Sbjct: 270 LHVASKRGN-TNMVKLLLDRGGQIDAKTRDGLT---PLHCAARSGHDQVVELLLERGAPL 325
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
+ + LS + A H+ + LL +
Sbjct: 326 LARTKNGLSPLHMAAQGDHVECVKHLLQH 354
Score = 56.6 bits (135), Expect = 2e-07
Identities = 54/218 (24%), Positives = 94/218 (42%), Gaps = 15/218 (6%)
Query: 427 HGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG 486
+G PLH A LL+ + TPL ++ N +++ L+ G
Sbjct: 595 NGLTPLHVAAHYDNQKVALLLLEKGASPHATA--KNGYTPLHIAAKKNQMQIASTLLNYG 652
Query: 487 -NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVA 544
N+ TK PL++A + + ++L+KG +I++S GL LH+ A
Sbjct: 653 AETNIV------TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST---KSGLTSLHLAA 703
Query: 545 KMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQN 604
+ + + +L +GAD D + P+ A G+ V LL+ GA+V K +
Sbjct: 704 QEDKVN-VADILTKHGADQDAHTKLG-YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNG 761
Query: 605 LSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLA 642
+ + A +GH ++NVLL + +A + LA
Sbjct: 762 YTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALA 799
>Hs10947052 [M] KOG4177 Ankyrin
Length = 3957
Score = 74.7 bits (182), Expect = 8e-13
Identities = 68/253 (26%), Positives = 115/253 (44%), Gaps = 40/253 (15%)
Query: 420 LLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVT 479
L++A+ + PLH A LGKT V LL+ + + + D TPL +S ++V
Sbjct: 489 LVDARAREEQTPLHIASRLGKTEIVQLLL--QHMAHPDAATTNGYTPLHISAREGQVDVA 546
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEK-------GDINLSRLR 532
+L+ G + SL TK F PL+VA + + AK++L++ G L+ L
Sbjct: 547 SVLLEAGAAH---SL--ATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLH 601
Query: 533 -----DSQ-------------------GLCPLHIVAKMGGGSELIKLLVSYGADPDEIDG 568
D+Q G PLHI AK ++ L++YGA+ + +
Sbjct: 602 VAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK-NQMQIASTLLNYGAETNIVTK 660
Query: 569 FNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAG 628
P+ A QEGH V +LL+ GA++ M + L+ + A E ++V ++L +
Sbjct: 661 -QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGA 719
Query: 629 NRKRYSAFPDRPL 641
++ ++ PL
Sbjct: 720 DQDAHTKLGYTPL 732
Score = 74.3 bits (181), Expect = 1e-12
Identities = 66/257 (25%), Positives = 113/257 (43%), Gaps = 25/257 (9%)
Query: 368 LTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIH 427
L + P DD+ H AA C H T +LL R NA+ ++
Sbjct: 352 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK--------------RANPNARALN 397
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G PLH AC+ + + LL+ +I + + TP+ ++ H+ + +L+ G
Sbjct: 398 GFTPLHIACKKNRIKVMELLVKYGA--SIQAITESGLTPIHVAAFMGHLNIVLLLLQNG- 454
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMG 547
SP + L++A E + +L G + +R R+ Q PLHI +++
Sbjct: 455 --ASPDVTNIRGET--ALHMAARAGQVEVVRCLLRNGALVDARAREEQ--TPLHIASRL- 507
Query: 548 GGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQ 607
G +E+++LL+ + A PD N + P+ + +EG VLLE GA + ++ +
Sbjct: 508 GKTEIVQLLLQHMAHPDAAT-TNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTP 566
Query: 608 VFYALWEGHLSVLNVLL 624
+ A G L V +LL
Sbjct: 567 LHVAAKYGSLDVAKLLL 583
Score = 64.7 bits (156), Expect = 8e-10
Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 19/202 (9%)
Query: 427 HGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG 486
+G PLH A + G TN V LL++ ID TPL + + H +V ++L+ +G
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRG--GQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 322
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEK----GDINLSRLRDSQGLCPLHI 542
+P L TK PL++A + E K +L+ D+ L L LH+
Sbjct: 323 ----APLLAR-TKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDY------LTALHV 371
Query: 543 VAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQ 602
A G + KLL+ A+P+ N + P+ A ++ +++L++ GA + +
Sbjct: 372 AAHC-GHYRVTKLLLDKRANPN-ARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITE 429
Query: 603 QNLSQVFYALWEGHLSVLNVLL 624
L+ + A + GHL+++ +LL
Sbjct: 430 SGLTPIHVAAFMGHLNIVLLLL 451
Score = 60.5 bits (145), Expect = 2e-08
Identities = 62/232 (26%), Positives = 92/232 (38%), Gaps = 44/232 (18%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G LH A G+ V +L+ NI+ TPL ++ NHI+V K L+ G
Sbjct: 97 GNTALHIASLAGQAEVVKVLVKEGA--NINAQSQNGFTPLYMAAQENHIDVVKYLLENG- 153
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE---KGDINLSRLR------------ 532
N S + T+ F PL VA + +A ++LE KG + L L
Sbjct: 154 ANQSTA----TEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAA 209
Query: 533 --------------------DSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKW 572
G PLHI A G + LL++ GA D N
Sbjct: 210 LLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHY-GNVNVATLLLNRGAAVD-FTARNGI 267
Query: 573 PPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLL 624
P+ A + G+ V++LL+ G + K + L+ + A GH V+ +LL
Sbjct: 268 TPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL 319
Score = 58.2 bits (139), Expect = 8e-08
Identities = 53/209 (25%), Positives = 92/209 (43%), Gaps = 27/209 (12%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDL--------LDNTSKTPLVLSIINNHIEVT 479
G PL A + G V++L+ + + L D+T L+L +N +
Sbjct: 163 GFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQS 222
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
K+++ + T+ F PL++A N A ++L +G R+ G+ P
Sbjct: 223 KMMVNRT-----------TESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN--GITP 269
Query: 540 LHIVAKMGGGSELIKLLVSYGA--DPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADV 597
LH+ +K G + ++KLL+ G D DG P+ A + GH V++LLE GA +
Sbjct: 270 LHVASKRGN-TNMVKLLLDRGGQIDAKTRDGLT---PLHCAARSGHDQVVELLLERGAPL 325
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
+ + LS + A H+ + LL +
Sbjct: 326 LARTKNGLSPLHMAAQGDHVECVKHLLQH 354
Score = 56.6 bits (135), Expect = 2e-07
Identities = 54/218 (24%), Positives = 94/218 (42%), Gaps = 15/218 (6%)
Query: 427 HGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG 486
+G PLH A LL+ + TPL ++ N +++ L+ G
Sbjct: 595 NGLTPLHVAAHYDNQKVALLLLEKGASPHATA--KNGYTPLHIAAKKNQMQIASTLLNYG 652
Query: 487 -NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVA 544
N+ TK PL++A + + ++L+KG +I++S GL LH+ A
Sbjct: 653 AETNIV------TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST---KSGLTSLHLAA 703
Query: 545 KMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQN 604
+ + + +L +GAD D + P+ A G+ V LL+ GA+V K +
Sbjct: 704 QEDKVN-VADILTKHGADQDAHTKLG-YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNG 761
Query: 605 LSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLA 642
+ + A +GH ++NVLL + +A + LA
Sbjct: 762 YTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALA 799
>At2g26660 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 287
Score = 74.7 bits (182), Expect = 8e-13
Identities = 57/183 (31%), Positives = 99/183 (53%), Gaps = 16/183 (8%)
Query: 1 MKFGKHLEGRQLE-LPEYNGHFINYKALKKLIKQLSVPAVSSYTNS---NDYMTLDETDE 56
MKFGK L + E LPE+ F++YK LKK +K + +V + N +D ++D TD
Sbjct: 1 MKFGKSLSNQIEETLPEWRDKFLSYKELKKKLKLMEPRSVENRPNKRSRSDSNSVD-TDP 59
Query: 57 SIRYQSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKGKLTSKK 116
++ + + + F LE ELEK N F++E+E + ++ L + +K K ++++
Sbjct: 60 TV---GMTKEELDFISLLEDELEKFNSFFVEQEEEYIIRLKELKDQV----AKAKNSNEE 112
Query: 117 SIAYRTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSHAKDFYLATVVSVQP 176
I I+ I F ++ L + LN TG +K+LKK+DKR+ + + ++ V+ +P
Sbjct: 113 MI---NIKKEIVDFHGEMVLLMNYSALNYTGLAKILKKYDKRTGALIRLPFIQKVLQ-EP 168
Query: 177 VFT 179
FT
Sbjct: 169 FFT 171
>At5g20150 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 256
Score = 74.3 bits (181), Expect = 1e-12
Identities = 59/186 (31%), Positives = 93/186 (49%), Gaps = 17/186 (9%)
Query: 1 MKFGKHLEGR-QLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIR 59
MKFGK L + + LPE+ F++YK LKK +K + S T L + S+
Sbjct: 1 MKFGKSLSNQIEQTLPEWQDKFLSYKELKKRLK-----LIGSKTADRPVKRLRLDEFSV- 54
Query: 60 YQSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKGKLTSKKSIA 119
+ + + +F LE ELEK N F++EKE + ++ R +K K + +K I
Sbjct: 55 --GISKEEINFIQLLEDELEKFNNFFVEKEEEYIIRLKEFRDRI----AKAKDSMEKMIK 108
Query: 120 YRTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSHAKDFYLATVVSVQPVFT 179
IR I F ++ LE + LN TG K+LKK+DKR+ + ++ V+ QP +T
Sbjct: 109 ---IRKEIVDFHGEMVLLENYSALNYTGLVKILKKYDKRTGDLMRLPFIQKVLQ-QPFYT 164
Query: 180 RNEVSK 185
+ + K
Sbjct: 165 TDLLFK 170
>SPAC6C3.08 [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 234
Score = 73.9 bits (180), Expect = 1e-12
Identities = 59/199 (29%), Positives = 92/199 (45%), Gaps = 8/199 (4%)
Query: 406 QYQNSIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKT 465
+Y IQ + LNA D R PLH+AC +GK N + L+ I D D T
Sbjct: 17 EYVEQAIQNDP--NSLNAVDDDKRTPLHWACSVGKVNTIYFLLKQPNI-KPDEKDEAGWT 73
Query: 466 PLVLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGD 525
PL++SI N + I ++ P++ T+ L+ A +++ +K
Sbjct: 74 PLMISINNRSVPDNVIEELINRSDVDPTIT--TRGGQTCLHYAAGKGRLSIVQLLCDKAP 131
Query: 526 INLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHAT 585
L R +D QG PLH A + G +++K L+S A + D + + P+ +A+ EGH
Sbjct: 132 -ELIRKKDLQGQTPLHRAAAV-GKIQVVKYLISQRAPLNTSDSYG-FTPLHFALAEGHPD 188
Query: 586 TVQVLLELGADVFMKDQQN 604
L+ GAD KD +N
Sbjct: 189 VGVELVRAGADTLRKDSEN 207
>Hs4502093 [M] KOG4177 Ankyrin
Length = 1088
Score = 73.6 bits (179), Expect = 2e-12
Identities = 60/199 (30%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 431 PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNL 490
PLH + LGK + V L+ N + TPL LS H +V L+ G
Sbjct: 123 PLHISARLGKADIVQQLLQQGASPNA--ATTSGYTPLHLSAREGHEDVAAFLLDHG---- 176
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
SL TK F PL+VA E A ++L+K GL PLH+ A
Sbjct: 177 -ASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSAS--PDAAGKSGLTPLHVAAHYDN-Q 232
Query: 551 ELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFY 610
++ LL+ GA P N + P+ A ++ LLE GAD +Q ++ V
Sbjct: 233 KVALLLLDQGASPHAA-AKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 291
Query: 611 ALWEGHLSVLNVLLSYAGN 629
A EGH+ ++++LL N
Sbjct: 292 AAQEGHVDMVSLLLGRNAN 310
Score = 65.5 bits (158), Expect = 5e-10
Identities = 55/240 (22%), Positives = 112/240 (45%), Gaps = 18/240 (7%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
NA+ ++G PLH AC+ + + LL+ +I + + TP+ ++ H+ +
Sbjct: 15 NAKALNGFTPLHIACKKNRIKVMELLLKHGA--SIQAVTESGLTPIHVAAFMGHVNIVSQ 72
Query: 482 LIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLH 541
L+ G + ++ T L++A + E + +++ G ++ +D Q PLH
Sbjct: 73 LMHHGASPNTTNVRGET-----ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLH 125
Query: 542 IVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKD 601
I A++ G +++++ L+ GA P+ + + P+ + +EGH LL+ GA + +
Sbjct: 126 ISARL-GKADIVQQLLQQGASPNAAT-TSGYTPLHLSAREGHEDVAAFLLDHGASLSITT 183
Query: 602 QQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPSDPGELFSDDQLSL 661
++ + + A G L V N+LL + SA PD L P + + +++L
Sbjct: 184 KKGFTPLHVAAKYGKLEVANLLL-------QKSASPDAAGKSGLTPLHVAAHYDNQKVAL 236
>Hs10947056 [M] KOG4177 Ankyrin
Length = 4377
Score = 73.6 bits (179), Expect = 2e-12
Identities = 60/199 (30%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 431 PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNL 490
PLH + LGK + V L+ N + TPL LS H +V L+ G
Sbjct: 502 PLHISARLGKADIVQQLLQQGASPNA--ATTSGYTPLHLSAREGHEDVAAFLLDHG---- 555
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
SL TK F PL+VA E A ++L+K GL PLH+ A
Sbjct: 556 -ASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSAS--PDAAGKSGLTPLHVAAHYDN-Q 611
Query: 551 ELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFY 610
++ LL+ GA P N + P+ A ++ LLE GAD +Q ++ V
Sbjct: 612 KVALLLLDQGASPHAA-AKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 670
Query: 611 ALWEGHLSVLNVLLSYAGN 629
A EGH+ ++++LL N
Sbjct: 671 AAQEGHVDMVSLLLGRNAN 689
Score = 68.6 bits (166), Expect = 6e-11
Identities = 66/294 (22%), Positives = 131/294 (44%), Gaps = 32/294 (10%)
Query: 368 LTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIH 427
L ++ P DD+ H AA C H Y+ ++ ++A NA+ ++
Sbjct: 354 LQHNVPVDDVTNDYLTALHVAAHCGH-----------YKVAKVLLDKKANP---NAKALN 399
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G PLH AC+ + + LL+ +I + + TP+ ++ H+ + L+ G
Sbjct: 400 GFTPLHIACKKNRIKVMELLLKHGA--SIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMG 547
+ ++ T L++A + E + +++ G ++ +D Q PLHI A++
Sbjct: 458 SPNTTNVRGET-----ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARL- 509
Query: 548 GGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQ 607
G +++++ L+ GA P+ + + P+ + +EGH LL+ GA + + ++ +
Sbjct: 510 GKADIVQQLLQQGASPNAAT-TSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTP 568
Query: 608 VFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPSDPGELFSDDQLSL 661
+ A G L V N+LL + SA PD L P + + +++L
Sbjct: 569 LHVAAKYGKLEVANLLL-------QKSASPDAAGKSGLTPLHVAAHYDNQKVAL 615
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/246 (26%), Positives = 102/246 (40%), Gaps = 39/246 (15%)
Query: 409 NSIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLV 468
+ ++Q+EA ++A G LH A G+ V +L+ N++ TPL
Sbjct: 91 SELLQREAN---VDAATKKGNTALHIASLAGQAEVVKVLVTNGA--NVNAQSQNGFTPLY 145
Query: 469 LSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE---KGD 525
++ NH+EV K L+ G S SL T+ F PL VA + + ++LE KG
Sbjct: 146 MAAQENHLEVVKFLLDNG---ASQSLA--TEDGFTPLAVALQQGHDQVVSLLLENDTKGK 200
Query: 526 INLSRLR------------------------DSQGLCPLHIVAKMGGGSELIKLLVSYGA 561
+ L L G PLHI A G + LL++ A
Sbjct: 201 VRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGN-INVATLLLNRAA 259
Query: 562 DPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLN 621
D N P+ A + G+A V++LL+ GA + K + L+ + GH V+
Sbjct: 260 AVD-FTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVE 318
Query: 622 VLLSYA 627
+LL A
Sbjct: 319 MLLDRA 324
Score = 58.9 bits (141), Expect = 4e-08
Identities = 64/233 (27%), Positives = 102/233 (43%), Gaps = 20/233 (8%)
Query: 400 LLAALYQYQNSIIQQEAFRKLLNAQDIHG--RMP-LHYACELGKTNFVSLLINTELIDNI 456
L AL Q + ++ LL D G R+P LH A T +LL+ + +N
Sbjct: 177 LAVALQQGHDQVVS------LLLENDTKGKVRLPALHIAARKDDTKAAALLLQND--NNA 228
Query: 457 DLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEA 516
D+ + TPL ++ +I V +L+ N + ++ + PL+VA N
Sbjct: 229 DVESKSGFTPLHIAAHYGNINVATLLL-----NRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 517 AKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIF 576
K++L++G ++ RD GL PLH A+ G +++++L+ A P N P+
Sbjct: 284 VKLLLDRGAKIDAKTRD--GLTPLHCGAR-SGHEQVVEMLLDRAA-PILSKTKNGLSPLH 339
Query: 577 YAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
A Q H VQ+LL+ V L+ + A GH V VLL N
Sbjct: 340 MATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKAN 392
>Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1176
Score = 73.2 bits (178), Expect = 2e-12
Identities = 65/239 (27%), Positives = 108/239 (44%), Gaps = 14/239 (5%)
Query: 411 IIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLS 470
+IQ+ RK L H R L+ + + G+ V L++ L N + +TPL +
Sbjct: 603 VIQESERRKKLR---FHPRQ-LYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAA 658
Query: 471 IINNHIEVTKILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLS 529
+E+ +L+ G N+N K Q PL A N + E A+ ++++G S
Sbjct: 659 AQKGSVEICHVLLQAGANINAVD------KQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQV 589
+ D G LH AK+G E++ LL+S G W PI +A + H +++
Sbjct: 713 KEED--GSTCLHHAAKIGN-LEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRM 769
Query: 590 LLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPS 648
LL GADV + D + + +A + G ++ VLL+ + + D PL + R S
Sbjct: 770 LLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARES 828
>Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1210
Score = 73.2 bits (178), Expect = 2e-12
Identities = 65/239 (27%), Positives = 108/239 (44%), Gaps = 14/239 (5%)
Query: 411 IIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLS 470
+IQ+ RK L H R L+ + + G+ V L++ L N + +TPL +
Sbjct: 637 VIQESERRKKLR---FHPRQ-LYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAA 692
Query: 471 IINNHIEVTKILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLS 529
+E+ +L+ G N+N K Q PL A N + E A+ ++++G S
Sbjct: 693 AQKGSVEICHVLLQAGANINAVD------KQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQV 589
+ D G LH AK+G E++ LL+S G W PI +A + H +++
Sbjct: 747 KEED--GSTCLHHAAKIGN-LEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRM 803
Query: 590 LLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPS 648
LL GADV + D + + +A + G ++ VLL+ + + D PL + R S
Sbjct: 804 LLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARES 862
>Hs10947042 [M] KOG4177 Ankyrin
Length = 1719
Score = 72.4 bits (176), Expect = 4e-12
Identities = 65/236 (27%), Positives = 103/236 (43%), Gaps = 38/236 (16%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NA+ + PLH A +G TN V LL+ N +L TPL ++ H+E
Sbjct: 463 VNAKAKDDQTPLHCAARIGHTNMVKLLLENNA--NPNLATTAGHTPLHIAAREGHVETVL 520
Query: 481 ILIAQ---------------------GNVNLSPSLCE-------GTKPQFHPLNVACSNK 512
L+ + G V ++ L E K PL+VA +
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 513 NYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYG--ADPDEIDGFN 570
N + K++L +G S + G PLHI AK E+ + L+ YG A+ + + G
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWN--GYTPLHIAAKQNQ-VEVARSLLQYGGSANAESVQGVT 637
Query: 571 KWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
P+ A QEGHA V +LL A+ + ++ L+ + EGH+ V +VL+ +
Sbjct: 638 ---PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH 690
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 29/259 (11%)
Query: 368 LTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIH 427
L Y DD+ H AA C H VLL N++ ++
Sbjct: 325 LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDK--------------GAKPNSRALN 370
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G PLH AC+ + LL+ T +ID + + TPL ++ H+ + K L+ +G
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGA--SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 428
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLSRLRDSQGLCPLHIVAK 545
+ N+S E PL++A + E AK +L+ K +N ++ +D Q PLH A+
Sbjct: 429 SPNVSNVKVE------TPLHMAARAGHTEVAKYLLQNKAKVN-AKAKDDQ--TPLHCAAR 479
Query: 546 MGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNL 605
+ G + ++KLL+ A+P+ + P+ A +EGH TV LLE A ++
Sbjct: 480 I-GHTNMVKLLLENNANPN-LATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGF 537
Query: 606 SQVFYALWEGHLSVLNVLL 624
+ + A G + V +LL
Sbjct: 538 TPLHVAAKYGKVRVAELLL 556
Score = 70.5 bits (171), Expect = 1e-11
Identities = 70/296 (23%), Positives = 125/296 (41%), Gaps = 56/296 (18%)
Query: 410 SIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVL 469
+++++EA + + + G PLH A + GK LL+ + N TPL +
Sbjct: 521 ALLEKEASQACMTKK---GFTPLHVAAKYGKVRVAELLLERDAHPNA--AGKNGLTPLHV 575
Query: 470 SIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLS 529
++ +N++++ K+L+ +G SP+ T PL++A E A+ +L+ G +
Sbjct: 576 AVHHNNLDIVKLLLPRGGSPHSPAWNGYT-----PLHIAAKQNQVEVARSLLQYG--GSA 628
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQV 589
QG+ PLH+ A+ G +E++ LL+S A+ + + + P+ QEGH V
Sbjct: 629 NAESVQGVTPLHLAAQEGH-AEMVALLLSKQANGN-LGNKSGLTPLHLVAQEGHVPVADV 686
Query: 590 LLELG---------------------------------ADVFMKDQQNLSQVFYALWEGH 616
L++ G ADV K + S + A +GH
Sbjct: 687 LIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGH 746
Query: 617 LSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPSDPGELFSDDQLSLNDSLKDIPDFT 672
++ +LL + S+ PLA + R +S+ D LK + D T
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG---------YISVTDVLKVVTDET 793
Score = 65.9 bits (159), Expect = 4e-10
Identities = 64/245 (26%), Positives = 104/245 (42%), Gaps = 38/245 (15%)
Query: 413 QQEAFRKLLN------AQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTP 466
Q E R+L+N AQ G PL+ A + V L+ N+ D TP
Sbjct: 90 QDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF--TP 147
Query: 467 LVLSIINNHIEVTKILI---AQGNVNL---------------------SPSLCEGTKPQF 502
L +++ H V LI +G V L P+ +K F
Sbjct: 148 LAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGF 207
Query: 503 HPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGA 561
PL++A +N A+++L +G +N + G+ PLHI ++ G +++LL+ GA
Sbjct: 208 TPLHIAAHYENLNVAQLLLNRGASVNFT---PQNGITPLHIASRR-GNVIMVRLLLDRGA 263
Query: 562 DPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLN 621
E ++ P+ A + GH ++LL+ GA + K + LS + A HL +
Sbjct: 264 Q-IETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 322
Query: 622 VLLSY 626
+LL Y
Sbjct: 323 LLLQY 327
Score = 63.9 bits (154), Expect = 1e-09
Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 13/210 (6%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTEL-IDNIDLLDNTSKTPLVLSIINNHIEVT 479
+ A+ +G P+H A + + V LL+ + ID+I L TPL ++ H V
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL---DHLTPLHVAAHCGHHRVA 354
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
K+L+ +G S +L F PL++AC + +++L+ G ++ + +S GL P
Sbjct: 355 KVLLDKGAKPNSRAL-----NGFTPLHIACKKNHVRVMELLLKTG-ASIDAVTES-GLTP 407
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ + MG ++K L+ GA P+ + P+ A + GH + LL+ A V
Sbjct: 408 LHVASFMGH-LPIVKNLLQRGASPN-VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNA 465
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
K + + + + A GH +++ +LL N
Sbjct: 466 KAKDDQTPLHCAARIGHTNMVKLLLENNAN 495
Score = 60.5 bits (145), Expect = 2e-08
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 14/198 (7%)
Query: 429 RMP-LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
R+P LH A T ++L+ + N D+L T TPL ++ ++ V ++L+ +G
Sbjct: 173 RLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA 230
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
+VN +P + PL++A N +++L++G ++ +D L PLH A+
Sbjct: 231 SVNFTP------QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE--LTPLHCAAR- 281
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
G + ++L+ +GA P + N PI A Q H V++LL+ A++ +L+
Sbjct: 282 NGHVRISEILLDHGA-PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLT 340
Query: 607 QVFYALWEGHLSVLNVLL 624
+ A GH V VLL
Sbjct: 341 PLHVAAHCGHHRVAKVLL 358
>Hs10947040 [M] KOG4177 Ankyrin
Length = 1880
Score = 72.4 bits (176), Expect = 4e-12
Identities = 65/236 (27%), Positives = 103/236 (43%), Gaps = 38/236 (16%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NA+ + PLH A +G TN V LL+ N +L TPL ++ H+E
Sbjct: 463 VNAKAKDDQTPLHCAARIGHTNMVKLLLENNA--NPNLATTAGHTPLHIAAREGHVETVL 520
Query: 481 ILIAQ---------------------GNVNLSPSLCE-------GTKPQFHPLNVACSNK 512
L+ + G V ++ L E K PL+VA +
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 513 NYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYG--ADPDEIDGFN 570
N + K++L +G S + G PLHI AK E+ + L+ YG A+ + + G
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWN--GYTPLHIAAKQNQ-VEVARSLLQYGGSANAESVQGVT 637
Query: 571 KWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
P+ A QEGHA V +LL A+ + ++ L+ + EGH+ V +VL+ +
Sbjct: 638 ---PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH 690
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 29/259 (11%)
Query: 368 LTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIH 427
L Y DD+ H AA C H VLL N++ ++
Sbjct: 325 LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDK--------------GAKPNSRALN 370
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G PLH AC+ + LL+ T +ID + + TPL ++ H+ + K L+ +G
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGA--SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 428
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLSRLRDSQGLCPLHIVAK 545
+ N+S E PL++A + E AK +L+ K +N ++ +D Q PLH A+
Sbjct: 429 SPNVSNVKVE------TPLHMAARAGHTEVAKYLLQNKAKVN-AKAKDDQ--TPLHCAAR 479
Query: 546 MGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNL 605
+ G + ++KLL+ A+P+ + P+ A +EGH TV LLE A ++
Sbjct: 480 I-GHTNMVKLLLENNANPN-LATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGF 537
Query: 606 SQVFYALWEGHLSVLNVLL 624
+ + A G + V +LL
Sbjct: 538 TPLHVAAKYGKVRVAELLL 556
Score = 70.5 bits (171), Expect = 1e-11
Identities = 70/296 (23%), Positives = 125/296 (41%), Gaps = 56/296 (18%)
Query: 410 SIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVL 469
+++++EA + + + G PLH A + GK LL+ + N TPL +
Sbjct: 521 ALLEKEASQACMTKK---GFTPLHVAAKYGKVRVAELLLERDAHPNA--AGKNGLTPLHV 575
Query: 470 SIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLS 529
++ +N++++ K+L+ +G SP+ T PL++A E A+ +L+ G +
Sbjct: 576 AVHHNNLDIVKLLLPRGGSPHSPAWNGYT-----PLHIAAKQNQVEVARSLLQYG--GSA 628
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQV 589
QG+ PLH+ A+ G +E++ LL+S A+ + + + P+ QEGH V
Sbjct: 629 NAESVQGVTPLHLAAQEGH-AEMVALLLSKQANGN-LGNKSGLTPLHLVAQEGHVPVADV 686
Query: 590 LLELG---------------------------------ADVFMKDQQNLSQVFYALWEGH 616
L++ G ADV K + S + A +GH
Sbjct: 687 LIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGH 746
Query: 617 LSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPSDPGELFSDDQLSLNDSLKDIPDFT 672
++ +LL + S+ PLA + R +S+ D LK + D T
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG---------YISVTDVLKVVTDET 793
Score = 65.9 bits (159), Expect = 4e-10
Identities = 64/245 (26%), Positives = 104/245 (42%), Gaps = 38/245 (15%)
Query: 413 QQEAFRKLLN------AQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTP 466
Q E R+L+N AQ G PL+ A + V L+ N+ D TP
Sbjct: 90 QDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF--TP 147
Query: 467 LVLSIINNHIEVTKILI---AQGNVNL---------------------SPSLCEGTKPQF 502
L +++ H V LI +G V L P+ +K F
Sbjct: 148 LAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGF 207
Query: 503 HPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGA 561
PL++A +N A+++L +G +N + G+ PLHI ++ G +++LL+ GA
Sbjct: 208 TPLHIAAHYENLNVAQLLLNRGASVNFT---PQNGITPLHIASRR-GNVIMVRLLLDRGA 263
Query: 562 DPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLN 621
E ++ P+ A + GH ++LL+ GA + K + LS + A HL +
Sbjct: 264 Q-IETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 322
Query: 622 VLLSY 626
+LL Y
Sbjct: 323 LLLQY 327
Score = 63.9 bits (154), Expect = 1e-09
Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 13/210 (6%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTEL-IDNIDLLDNTSKTPLVLSIINNHIEVT 479
+ A+ +G P+H A + + V LL+ + ID+I L TPL ++ H V
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL---DHLTPLHVAAHCGHHRVA 354
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
K+L+ +G S +L F PL++AC + +++L+ G ++ + +S GL P
Sbjct: 355 KVLLDKGAKPNSRAL-----NGFTPLHIACKKNHVRVMELLLKTG-ASIDAVTES-GLTP 407
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ + MG ++K L+ GA P+ + P+ A + GH + LL+ A V
Sbjct: 408 LHVASFMGH-LPIVKNLLQRGASPN-VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNA 465
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
K + + + + A GH +++ +LL N
Sbjct: 466 KAKDDQTPLHCAARIGHTNMVKLLLENNAN 495
Score = 60.5 bits (145), Expect = 2e-08
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 14/198 (7%)
Query: 429 RMP-LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
R+P LH A T ++L+ + N D+L T TPL ++ ++ V ++L+ +G
Sbjct: 173 RLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA 230
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
+VN +P + PL++A N +++L++G ++ +D L PLH A+
Sbjct: 231 SVNFTP------QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE--LTPLHCAAR- 281
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
G + ++L+ +GA P + N PI A Q H V++LL+ A++ +L+
Sbjct: 282 NGHVRISEILLDHGA-PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLT 340
Query: 607 QVFYALWEGHLSVLNVLL 624
+ A GH V VLL
Sbjct: 341 PLHVAAHCGHHRVAKVLL 358
>Hs10947038 [M] KOG4177 Ankyrin
Length = 1881
Score = 72.4 bits (176), Expect = 4e-12
Identities = 65/236 (27%), Positives = 103/236 (43%), Gaps = 38/236 (16%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NA+ + PLH A +G TN V LL+ N +L TPL ++ H+E
Sbjct: 463 VNAKAKDDQTPLHCAARIGHTNMVKLLLENNA--NPNLATTAGHTPLHIAAREGHVETVL 520
Query: 481 ILIAQ---------------------GNVNLSPSLCE-------GTKPQFHPLNVACSNK 512
L+ + G V ++ L E K PL+VA +
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 513 NYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYG--ADPDEIDGFN 570
N + K++L +G S + G PLHI AK E+ + L+ YG A+ + + G
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWN--GYTPLHIAAKQNQ-VEVARSLLQYGGSANAESVQGVT 637
Query: 571 KWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
P+ A QEGHA V +LL A+ + ++ L+ + EGH+ V +VL+ +
Sbjct: 638 ---PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH 690
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 29/259 (11%)
Query: 368 LTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIH 427
L Y DD+ H AA C H VLL N++ ++
Sbjct: 325 LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDK--------------GAKPNSRALN 370
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G PLH AC+ + LL+ T +ID + + TPL ++ H+ + K L+ +G
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGA--SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 428
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLSRLRDSQGLCPLHIVAK 545
+ N+S E PL++A + E AK +L+ K +N ++ +D Q PLH A+
Sbjct: 429 SPNVSNVKVE------TPLHMAARAGHTEVAKYLLQNKAKVN-AKAKDDQ--TPLHCAAR 479
Query: 546 MGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNL 605
+ G + ++KLL+ A+P+ + P+ A +EGH TV LLE A ++
Sbjct: 480 I-GHTNMVKLLLENNANPN-LATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGF 537
Query: 606 SQVFYALWEGHLSVLNVLL 624
+ + A G + V +LL
Sbjct: 538 TPLHVAAKYGKVRVAELLL 556
Score = 70.5 bits (171), Expect = 1e-11
Identities = 70/296 (23%), Positives = 125/296 (41%), Gaps = 56/296 (18%)
Query: 410 SIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVL 469
+++++EA + + + G PLH A + GK LL+ + N TPL +
Sbjct: 521 ALLEKEASQACMTKK---GFTPLHVAAKYGKVRVAELLLERDAHPNA--AGKNGLTPLHV 575
Query: 470 SIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLS 529
++ +N++++ K+L+ +G SP+ T PL++A E A+ +L+ G +
Sbjct: 576 AVHHNNLDIVKLLLPRGGSPHSPAWNGYT-----PLHIAAKQNQVEVARSLLQYG--GSA 628
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQV 589
QG+ PLH+ A+ G +E++ LL+S A+ + + + P+ QEGH V
Sbjct: 629 NAESVQGVTPLHLAAQEGH-AEMVALLLSKQANGN-LGNKSGLTPLHLVAQEGHVPVADV 686
Query: 590 LLELG---------------------------------ADVFMKDQQNLSQVFYALWEGH 616
L++ G ADV K + S + A +GH
Sbjct: 687 LIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGH 746
Query: 617 LSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPSDPGELFSDDQLSLNDSLKDIPDFT 672
++ +LL + S+ PLA + R +S+ D LK + D T
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG---------YISVTDVLKVVTDET 793
Score = 65.9 bits (159), Expect = 4e-10
Identities = 64/245 (26%), Positives = 104/245 (42%), Gaps = 38/245 (15%)
Query: 413 QQEAFRKLLN------AQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTP 466
Q E R+L+N AQ G PL+ A + V L+ N+ D TP
Sbjct: 90 QDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF--TP 147
Query: 467 LVLSIINNHIEVTKILI---AQGNVNL---------------------SPSLCEGTKPQF 502
L +++ H V LI +G V L P+ +K F
Sbjct: 148 LAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGF 207
Query: 503 HPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGA 561
PL++A +N A+++L +G +N + G+ PLHI ++ G +++LL+ GA
Sbjct: 208 TPLHIAAHYENLNVAQLLLNRGASVNFT---PQNGITPLHIASRR-GNVIMVRLLLDRGA 263
Query: 562 DPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLN 621
E ++ P+ A + GH ++LL+ GA + K + LS + A HL +
Sbjct: 264 Q-IETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 322
Query: 622 VLLSY 626
+LL Y
Sbjct: 323 LLLQY 327
Score = 63.9 bits (154), Expect = 1e-09
Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 13/210 (6%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTEL-IDNIDLLDNTSKTPLVLSIINNHIEVT 479
+ A+ +G P+H A + + V LL+ + ID+I L TPL ++ H V
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL---DHLTPLHVAAHCGHHRVA 354
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
K+L+ +G S +L F PL++AC + +++L+ G ++ + +S GL P
Sbjct: 355 KVLLDKGAKPNSRAL-----NGFTPLHIACKKNHVRVMELLLKTG-ASIDAVTES-GLTP 407
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ + MG ++K L+ GA P+ + P+ A + GH + LL+ A V
Sbjct: 408 LHVASFMGH-LPIVKNLLQRGASPN-VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNA 465
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
K + + + + A GH +++ +LL N
Sbjct: 466 KAKDDQTPLHCAARIGHTNMVKLLLENNAN 495
Score = 60.5 bits (145), Expect = 2e-08
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 14/198 (7%)
Query: 429 RMP-LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
R+P LH A T ++L+ + N D+L T TPL ++ ++ V ++L+ +G
Sbjct: 173 RLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA 230
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
+VN +P + PL++A N +++L++G ++ +D L PLH A+
Sbjct: 231 SVNFTP------QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE--LTPLHCAAR- 281
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
G + ++L+ +GA P + N PI A Q H V++LL+ A++ +L+
Sbjct: 282 NGHVRISEILLDHGA-PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLT 340
Query: 607 QVFYALWEGHLSVLNVLL 624
+ A GH V VLL
Sbjct: 341 PLHVAAHCGHHRVAKVLL 358
>Hs10947036 [M] KOG4177 Ankyrin
Length = 1856
Score = 72.4 bits (176), Expect = 4e-12
Identities = 65/236 (27%), Positives = 103/236 (43%), Gaps = 38/236 (16%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NA+ + PLH A +G TN V LL+ N +L TPL ++ H+E
Sbjct: 463 VNAKAKDDQTPLHCAARIGHTNMVKLLLENNA--NPNLATTAGHTPLHIAAREGHVETVL 520
Query: 481 ILIAQ---------------------GNVNLSPSLCE-------GTKPQFHPLNVACSNK 512
L+ + G V ++ L E K PL+VA +
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 513 NYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYG--ADPDEIDGFN 570
N + K++L +G S + G PLHI AK E+ + L+ YG A+ + + G
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWN--GYTPLHIAAKQNQ-VEVARSLLQYGGSANAESVQGVT 637
Query: 571 KWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
P+ A QEGHA V +LL A+ + ++ L+ + EGH+ V +VL+ +
Sbjct: 638 ---PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH 690
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 29/259 (11%)
Query: 368 LTYSDPDDDLVFARHNMFHEAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIH 427
L Y DD+ H AA C H VLL N++ ++
Sbjct: 325 LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDK--------------GAKPNSRALN 370
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G PLH AC+ + LL+ T +ID + + TPL ++ H+ + K L+ +G
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGA--SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 428
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLSRLRDSQGLCPLHIVAK 545
+ N+S E PL++A + E AK +L+ K +N ++ +D Q PLH A+
Sbjct: 429 SPNVSNVKVE------TPLHMAARAGHTEVAKYLLQNKAKVN-AKAKDDQ--TPLHCAAR 479
Query: 546 MGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNL 605
+ G + ++KLL+ A+P+ + P+ A +EGH TV LLE A ++
Sbjct: 480 I-GHTNMVKLLLENNANPN-LATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGF 537
Query: 606 SQVFYALWEGHLSVLNVLL 624
+ + A G + V +LL
Sbjct: 538 TPLHVAAKYGKVRVAELLL 556
Score = 70.5 bits (171), Expect = 1e-11
Identities = 70/296 (23%), Positives = 125/296 (41%), Gaps = 56/296 (18%)
Query: 410 SIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVL 469
+++++EA + + + G PLH A + GK LL+ + N TPL +
Sbjct: 521 ALLEKEASQACMTKK---GFTPLHVAAKYGKVRVAELLLERDAHPNA--AGKNGLTPLHV 575
Query: 470 SIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLS 529
++ +N++++ K+L+ +G SP+ T PL++A E A+ +L+ G +
Sbjct: 576 AVHHNNLDIVKLLLPRGGSPHSPAWNGYT-----PLHIAAKQNQVEVARSLLQYG--GSA 628
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQV 589
QG+ PLH+ A+ G +E++ LL+S A+ + + + P+ QEGH V
Sbjct: 629 NAESVQGVTPLHLAAQEGH-AEMVALLLSKQANGN-LGNKSGLTPLHLVAQEGHVPVADV 686
Query: 590 LLELG---------------------------------ADVFMKDQQNLSQVFYALWEGH 616
L++ G ADV K + S + A +GH
Sbjct: 687 LIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGH 746
Query: 617 LSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPSDPGELFSDDQLSLNDSLKDIPDFT 672
++ +LL + S+ PLA + R +S+ D LK + D T
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG---------YISVTDVLKVVTDET 793
Score = 65.9 bits (159), Expect = 4e-10
Identities = 64/245 (26%), Positives = 104/245 (42%), Gaps = 38/245 (15%)
Query: 413 QQEAFRKLLN------AQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTP 466
Q E R+L+N AQ G PL+ A + V L+ N+ D TP
Sbjct: 90 QDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF--TP 147
Query: 467 LVLSIINNHIEVTKILI---AQGNVNL---------------------SPSLCEGTKPQF 502
L +++ H V LI +G V L P+ +K F
Sbjct: 148 LAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGF 207
Query: 503 HPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGA 561
PL++A +N A+++L +G +N + G+ PLHI ++ G +++LL+ GA
Sbjct: 208 TPLHIAAHYENLNVAQLLLNRGASVNFT---PQNGITPLHIASRR-GNVIMVRLLLDRGA 263
Query: 562 DPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLN 621
E ++ P+ A + GH ++LL+ GA + K + LS + A HL +
Sbjct: 264 Q-IETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 322
Query: 622 VLLSY 626
+LL Y
Sbjct: 323 LLLQY 327
Score = 63.9 bits (154), Expect = 1e-09
Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 13/210 (6%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTEL-IDNIDLLDNTSKTPLVLSIINNHIEVT 479
+ A+ +G P+H A + + V LL+ + ID+I L TPL ++ H V
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL---DHLTPLHVAAHCGHHRVA 354
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
K+L+ +G S +L F PL++AC + +++L+ G ++ + +S GL P
Sbjct: 355 KVLLDKGAKPNSRAL-----NGFTPLHIACKKNHVRVMELLLKTG-ASIDAVTES-GLTP 407
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ + MG ++K L+ GA P+ + P+ A + GH + LL+ A V
Sbjct: 408 LHVASFMGH-LPIVKNLLQRGASPN-VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNA 465
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
K + + + + A GH +++ +LL N
Sbjct: 466 KAKDDQTPLHCAARIGHTNMVKLLLENNAN 495
Score = 60.5 bits (145), Expect = 2e-08
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 14/198 (7%)
Query: 429 RMP-LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
R+P LH A T ++L+ + N D+L T TPL ++ ++ V ++L+ +G
Sbjct: 173 RLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA 230
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
+VN +P + PL++A N +++L++G ++ +D L PLH A+
Sbjct: 231 SVNFTP------QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE--LTPLHCAAR- 281
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
G + ++L+ +GA P + N PI A Q H V++LL+ A++ +L+
Sbjct: 282 NGHVRISEILLDHGA-PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLT 340
Query: 607 QVFYALWEGHLSVLNVLL 624
+ A GH V VLL
Sbjct: 341 PLHVAAHCGHHRVAKVLL 358
>CE06705 [M] KOG4177 Ankyrin
Length = 1815
Score = 71.6 bits (174), Expect = 7e-12
Identities = 64/206 (31%), Positives = 96/206 (46%), Gaps = 19/206 (9%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNID--LLDNTSKTPLVLSIINNHIEVT 479
NA PLH A + G+ +L++ N D LL TPL L+ ++EV
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAGILLD----HNADKTLLTKKGFTPLHLASKYGNLEVV 573
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
++L+ +G +P EG K Q PL+VA N + A ++LE G ++ G P
Sbjct: 574 RLLLERG----TPVDIEG-KNQVTPLHVAAHYNNDKVAMLLLENGAS--AKAAAKNGYTP 626
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEID--GFNKWPPIFYAIQEGHATTVQVLLELGADV 597
LHI AK E+ L+ + ADP+ GF P+ + QEGH +L+E G+DV
Sbjct: 627 LHIAAKKNQ-MEIASTLLQFKADPNAKSRAGFT---PLHLSAQEGHKEISGLLIENGSDV 682
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVL 623
K L+ + E H+ V +L
Sbjct: 683 GAKANNGLTAMHLCAQEDHVPVAQIL 708
Score = 67.4 bits (163), Expect = 1e-10
Identities = 57/213 (26%), Positives = 97/213 (44%), Gaps = 19/213 (8%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N Q H PLH A + G+TN +LL++ I ID TPL + + H +V
Sbjct: 253 VNYQARHNISPLHVATKWGRTNMANLLLSRGAI--IDSRTKDLLTPLHCAARSGHDQVVD 310
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVIL----EKGDINLSRLRDSQG 536
+L+ QG + TK PL++A + +AA+ +L D+ +
Sbjct: 311 LLVVQG-----APISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDY------ 359
Query: 537 LCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGAD 596
L PLH+ A G + KLL+ ADP+ N + P+ A ++ V++LL+ A
Sbjct: 360 LTPLHVAAHC-GHVRVAKLLLDRSADPNS-RALNGFTPLHIACKKNRIKVVELLLKYRAA 417
Query: 597 VFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ + L+ + A + G ++++ LL N
Sbjct: 418 IEATTESGLTPLHVAAFMGAINIVIYLLQQGAN 450
Score = 64.7 bits (156), Expect = 8e-10
Identities = 57/222 (25%), Positives = 98/222 (43%), Gaps = 15/222 (6%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPL-VLSIINNHIEVTK 480
+ + + G PLH A +T+ V +LI +D +TPL + S + N V
Sbjct: 452 DVETVRGETPLHLAARANQTDVVRVLIRNGA--KVDAQARELQTPLHIASRLGNTDIVIL 509
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSR-LRDSQGLCP 539
+L A N N + T+ + PL++A E A ++L D N + L +G P
Sbjct: 510 LLQAGANSNAT------TRDNYSPLHIAAKEGQEEVAGILL---DHNADKTLLTKKGFTP 560
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ +K G E+++LL+ G P +I+G N+ P+ A + +LLE GA
Sbjct: 561 LHLASKYGN-LEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
+ + + A + + + + LL + + S PL
Sbjct: 619 AAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPL 660
Score = 63.9 bits (154), Expect = 1e-09
Identities = 63/203 (31%), Positives = 91/203 (44%), Gaps = 25/203 (12%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G LH A G++ V++L+ N+++ TPL ++ NH EV K L+ G
Sbjct: 99 GNTALHIASLAGQSLIVTILVENGA--NVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGA 156
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQG---LCPLHIV 543
N LS T+ F PL VA + V+LE DS+G L LHI
Sbjct: 157 NQALS------TEDGFTPLAVALQQGHDRVVAVLLEN---------DSKGKVRLPALHIA 201
Query: 544 AKMGGGSELIKLLVS-YGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQ 602
AK + LL + + D GF P+ A GH Q+LLE GA+V + +
Sbjct: 202 AKKDDTTAATLLLQNEHNPDVTSKSGFT---PLHIAAHYGHENVGQLLLEKGANVNYQAR 258
Query: 603 QNLSQVFYALWEGHLSVLNVLLS 625
N+S + A G ++ N+LLS
Sbjct: 259 HNISPLHVATKWGRTNMANLLLS 281
>CE06704 [M] KOG4177 Ankyrin
Length = 1867
Score = 71.6 bits (174), Expect = 7e-12
Identities = 64/206 (31%), Positives = 96/206 (46%), Gaps = 19/206 (9%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNID--LLDNTSKTPLVLSIINNHIEVT 479
NA PLH A + G+ +L++ N D LL TPL L+ ++EV
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAGILLD----HNADKTLLTKKGFTPLHLASKYGNLEVV 573
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
++L+ +G +P EG K Q PL+VA N + A ++LE G ++ G P
Sbjct: 574 RLLLERG----TPVDIEG-KNQVTPLHVAAHYNNDKVAMLLLENGAS--AKAAAKNGYTP 626
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEID--GFNKWPPIFYAIQEGHATTVQVLLELGADV 597
LHI AK E+ L+ + ADP+ GF P+ + QEGH +L+E G+DV
Sbjct: 627 LHIAAKKNQ-MEIASTLLQFKADPNAKSRAGFT---PLHLSAQEGHKEISGLLIENGSDV 682
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVL 623
K L+ + E H+ V +L
Sbjct: 683 GAKANNGLTAMHLCAQEDHVPVAQIL 708
Score = 67.4 bits (163), Expect = 1e-10
Identities = 57/213 (26%), Positives = 97/213 (44%), Gaps = 19/213 (8%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N Q H PLH A + G+TN +LL++ I ID TPL + + H +V
Sbjct: 253 VNYQARHNISPLHVATKWGRTNMANLLLSRGAI--IDSRTKDLLTPLHCAARSGHDQVVD 310
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVIL----EKGDINLSRLRDSQG 536
+L+ QG + TK PL++A + +AA+ +L D+ +
Sbjct: 311 LLVVQG-----APISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDY------ 359
Query: 537 LCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGAD 596
L PLH+ A G + KLL+ ADP+ N + P+ A ++ V++LL+ A
Sbjct: 360 LTPLHVAAHC-GHVRVAKLLLDRSADPNS-RALNGFTPLHIACKKNRIKVVELLLKYRAA 417
Query: 597 VFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ + L+ + A + G ++++ LL N
Sbjct: 418 IEATTESGLTPLHVAAFMGAINIVIYLLQQGAN 450
Score = 64.7 bits (156), Expect = 8e-10
Identities = 57/222 (25%), Positives = 98/222 (43%), Gaps = 15/222 (6%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPL-VLSIINNHIEVTK 480
+ + + G PLH A +T+ V +LI +D +TPL + S + N V
Sbjct: 452 DVETVRGETPLHLAARANQTDVVRVLIRNGA--KVDAQARELQTPLHIASRLGNTDIVIL 509
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSR-LRDSQGLCP 539
+L A N N + T+ + PL++A E A ++L D N + L +G P
Sbjct: 510 LLQAGANSNAT------TRDNYSPLHIAAKEGQEEVAGILL---DHNADKTLLTKKGFTP 560
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ +K G E+++LL+ G P +I+G N+ P+ A + +LLE GA
Sbjct: 561 LHLASKYGN-LEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
+ + + A + + + + LL + + S PL
Sbjct: 619 AAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPL 660
Score = 63.9 bits (154), Expect = 1e-09
Identities = 63/203 (31%), Positives = 91/203 (44%), Gaps = 25/203 (12%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G LH A G++ V++L+ N+++ TPL ++ NH EV K L+ G
Sbjct: 99 GNTALHIASLAGQSLIVTILVENGA--NVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGA 156
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQG---LCPLHIV 543
N LS T+ F PL VA + V+LE DS+G L LHI
Sbjct: 157 NQALS------TEDGFTPLAVALQQGHDRVVAVLLEN---------DSKGKVRLPALHIA 201
Query: 544 AKMGGGSELIKLLVS-YGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQ 602
AK + LL + + D GF P+ A GH Q+LLE GA+V + +
Sbjct: 202 AKKDDTTAATLLLQNEHNPDVTSKSGFT---PLHIAAHYGHENVGQLLLEKGANVNYQAR 258
Query: 603 QNLSQVFYALWEGHLSVLNVLLS 625
N+S + A G ++ N+LLS
Sbjct: 259 HNISPLHVATKWGRTNMANLLLS 281
>CE06703 [M] KOG4177 Ankyrin
Length = 1809
Score = 71.6 bits (174), Expect = 7e-12
Identities = 64/206 (31%), Positives = 96/206 (46%), Gaps = 19/206 (9%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNID--LLDNTSKTPLVLSIINNHIEVT 479
NA PLH A + G+ +L++ N D LL TPL L+ ++EV
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAGILLD----HNADKTLLTKKGFTPLHLASKYGNLEVV 573
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
++L+ +G +P EG K Q PL+VA N + A ++LE G ++ G P
Sbjct: 574 RLLLERG----TPVDIEG-KNQVTPLHVAAHYNNDKVAMLLLENGAS--AKAAAKNGYTP 626
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEID--GFNKWPPIFYAIQEGHATTVQVLLELGADV 597
LHI AK E+ L+ + ADP+ GF P+ + QEGH +L+E G+DV
Sbjct: 627 LHIAAKKNQ-MEIASTLLQFKADPNAKSRAGFT---PLHLSAQEGHKEISGLLIENGSDV 682
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVL 623
K L+ + E H+ V +L
Sbjct: 683 GAKANNGLTAMHLCAQEDHVPVAQIL 708
Score = 67.4 bits (163), Expect = 1e-10
Identities = 57/213 (26%), Positives = 97/213 (44%), Gaps = 19/213 (8%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N Q H PLH A + G+TN +LL++ I ID TPL + + H +V
Sbjct: 253 VNYQARHNISPLHVATKWGRTNMANLLLSRGAI--IDSRTKDLLTPLHCAARSGHDQVVD 310
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVIL----EKGDINLSRLRDSQG 536
+L+ QG + TK PL++A + +AA+ +L D+ +
Sbjct: 311 LLVVQG-----APISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDY------ 359
Query: 537 LCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGAD 596
L PLH+ A G + KLL+ ADP+ N + P+ A ++ V++LL+ A
Sbjct: 360 LTPLHVAAHC-GHVRVAKLLLDRSADPNS-RALNGFTPLHIACKKNRIKVVELLLKYRAA 417
Query: 597 VFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ + L+ + A + G ++++ LL N
Sbjct: 418 IEATTESGLTPLHVAAFMGAINIVIYLLQQGAN 450
Score = 64.7 bits (156), Expect = 8e-10
Identities = 57/222 (25%), Positives = 98/222 (43%), Gaps = 15/222 (6%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPL-VLSIINNHIEVTK 480
+ + + G PLH A +T+ V +LI +D +TPL + S + N V
Sbjct: 452 DVETVRGETPLHLAARANQTDVVRVLIRNGA--KVDAQARELQTPLHIASRLGNTDIVIL 509
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSR-LRDSQGLCP 539
+L A N N + T+ + PL++A E A ++L D N + L +G P
Sbjct: 510 LLQAGANSNAT------TRDNYSPLHIAAKEGQEEVAGILL---DHNADKTLLTKKGFTP 560
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ +K G E+++LL+ G P +I+G N+ P+ A + +LLE GA
Sbjct: 561 LHLASKYGN-LEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
+ + + A + + + + LL + + S PL
Sbjct: 619 AAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPL 660
Score = 63.9 bits (154), Expect = 1e-09
Identities = 63/203 (31%), Positives = 91/203 (44%), Gaps = 25/203 (12%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G LH A G++ V++L+ N+++ TPL ++ NH EV K L+ G
Sbjct: 99 GNTALHIASLAGQSLIVTILVENGA--NVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGA 156
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQG---LCPLHIV 543
N LS T+ F PL VA + V+LE DS+G L LHI
Sbjct: 157 NQALS------TEDGFTPLAVALQQGHDRVVAVLLEN---------DSKGKVRLPALHIA 201
Query: 544 AKMGGGSELIKLLVS-YGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQ 602
AK + LL + + D GF P+ A GH Q+LLE GA+V + +
Sbjct: 202 AKKDDTTAATLLLQNEHNPDVTSKSGFT---PLHIAAHYGHENVGQLLLEKGANVNYQAR 258
Query: 603 QNLSQVFYALWEGHLSVLNVLLS 625
N+S + A G ++ N+LLS
Sbjct: 259 HNISPLHVATKWGRTNMANLLLS 281
>CE06702 [M] KOG4177 Ankyrin
Length = 2039
Score = 71.6 bits (174), Expect = 7e-12
Identities = 64/206 (31%), Positives = 96/206 (46%), Gaps = 19/206 (9%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNID--LLDNTSKTPLVLSIINNHIEVT 479
NA PLH A + G+ +L++ N D LL TPL L+ ++EV
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAGILLD----HNADKTLLTKKGFTPLHLASKYGNLEVV 573
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
++L+ +G +P EG K Q PL+VA N + A ++LE G ++ G P
Sbjct: 574 RLLLERG----TPVDIEG-KNQVTPLHVAAHYNNDKVAMLLLENGAS--AKAAAKNGYTP 626
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEID--GFNKWPPIFYAIQEGHATTVQVLLELGADV 597
LHI AK E+ L+ + ADP+ GF P+ + QEGH +L+E G+DV
Sbjct: 627 LHIAAKKNQ-MEIASTLLQFKADPNAKSRAGFT---PLHLSAQEGHKEISGLLIENGSDV 682
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVL 623
K L+ + E H+ V +L
Sbjct: 683 GAKANNGLTAMHLCAQEDHVPVAQIL 708
Score = 67.4 bits (163), Expect = 1e-10
Identities = 57/213 (26%), Positives = 97/213 (44%), Gaps = 19/213 (8%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N Q H PLH A + G+TN +LL++ I ID TPL + + H +V
Sbjct: 253 VNYQARHNISPLHVATKWGRTNMANLLLSRGAI--IDSRTKDLLTPLHCAARSGHDQVVD 310
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVIL----EKGDINLSRLRDSQG 536
+L+ QG + TK PL++A + +AA+ +L D+ +
Sbjct: 311 LLVVQG-----APISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDY------ 359
Query: 537 LCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGAD 596
L PLH+ A G + KLL+ ADP+ N + P+ A ++ V++LL+ A
Sbjct: 360 LTPLHVAAHC-GHVRVAKLLLDRSADPNS-RALNGFTPLHIACKKNRIKVVELLLKYRAA 417
Query: 597 VFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ + L+ + A + G ++++ LL N
Sbjct: 418 IEATTESGLTPLHVAAFMGAINIVIYLLQQGAN 450
Score = 64.7 bits (156), Expect = 8e-10
Identities = 57/222 (25%), Positives = 98/222 (43%), Gaps = 15/222 (6%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPL-VLSIINNHIEVTK 480
+ + + G PLH A +T+ V +LI +D +TPL + S + N V
Sbjct: 452 DVETVRGETPLHLAARANQTDVVRVLIRNGA--KVDAQARELQTPLHIASRLGNTDIVIL 509
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSR-LRDSQGLCP 539
+L A N N + T+ + PL++A E A ++L D N + L +G P
Sbjct: 510 LLQAGANSNAT------TRDNYSPLHIAAKEGQEEVAGILL---DHNADKTLLTKKGFTP 560
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ +K G E+++LL+ G P +I+G N+ P+ A + +LLE GA
Sbjct: 561 LHLASKYGN-LEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
+ + + A + + + + LL + + S PL
Sbjct: 619 AAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPL 660
Score = 63.9 bits (154), Expect = 1e-09
Identities = 63/203 (31%), Positives = 91/203 (44%), Gaps = 25/203 (12%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G LH A G++ V++L+ N+++ TPL ++ NH EV K L+ G
Sbjct: 99 GNTALHIASLAGQSLIVTILVENGA--NVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGA 156
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQG---LCPLHIV 543
N LS T+ F PL VA + V+LE DS+G L LHI
Sbjct: 157 NQALS------TEDGFTPLAVALQQGHDRVVAVLLEN---------DSKGKVRLPALHIA 201
Query: 544 AKMGGGSELIKLLVS-YGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQ 602
AK + LL + + D GF P+ A GH Q+LLE GA+V + +
Sbjct: 202 AKKDDTTAATLLLQNEHNPDVTSKSGFT---PLHIAAHYGHENVGQLLLEKGANVNYQAR 258
Query: 603 QNLSQVFYALWEGHLSVLNVLLS 625
N+S + A G ++ N+LLS
Sbjct: 259 HNISPLHVATKWGRTNMANLLLS 281
>7301133 [T] KOG4369 RTK signaling protein MASK/UNC-44
Length = 2441
Score = 71.2 bits (173), Expect = 9e-12
Identities = 63/200 (31%), Positives = 95/200 (47%), Gaps = 11/200 (5%)
Query: 432 LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLS 491
L AC G V LLIN NI+ D TPL+L+ H +V IL+ +
Sbjct: 757 LTLACAGGHEELVELLINRGA--NIEHRDKKGFTPLILAATAGHDKVVDILLKHSAELEA 814
Query: 492 PSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSE 551
S E TK PL++ACS YE +++L G R+ PL + A GG
Sbjct: 815 QS--ERTKDT--PLSLACSGGRYEVVELLLSVG--ANKEHRNVSDYTPLSLAAS-GGYVN 867
Query: 552 LIKLLVSYGADPDEIDGFNKW-PPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVF- 609
+IKLL+S+GA+ + G P+ A GH V++LL+ G+D+ + + N +
Sbjct: 868 IIKLLLSHGAEINSRTGSKLGISPLMLAAMNGHTPAVKLLLDQGSDINAQIETNRNTALT 927
Query: 610 YALWEGHLSVLNVLLSYAGN 629
A ++G V+++LL N
Sbjct: 928 LACFQGRHEVVSLLLDRRAN 947
Score = 57.8 bits (138), Expect = 1e-07
Identities = 54/226 (23%), Positives = 95/226 (41%), Gaps = 33/226 (14%)
Query: 431 PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG---- 486
PL A G N + LL++ N +PL+L+ +N H K+L+ QG
Sbjct: 856 PLSLAASGGYVNIIKLLLSHGAEINSRTGSKLGISPLMLAAMNGHTPAVKLLLDQGSDIN 915
Query: 487 -------NVNLSPSLCEG------------------TKPQFHPLNVACSNKNYEAAKVIL 521
N L+ + +G K PL A S E +V+L
Sbjct: 916 AQIETNRNTALTLACFQGRHEVVSLLLDRRANVEHRAKTGLTPLMEAASGGYIEVGRVLL 975
Query: 522 EKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQ 580
+KG D+N + + S+ +A G + ++LL+S A E+ P++ A
Sbjct: 976 DKGADVNAAPVPTSRDTALT--IAADKGHQKFVELLLSRNASV-EVKNKKGNSPLWLAAH 1032
Query: 581 EGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
GH + V++L + AD+ +D + +S + A +GH ++ ++ Y
Sbjct: 1033 GGHLSVVELLYDHNADIDSQDNRRVSCLMAAFRKGHTKIVKWMVQY 1078
>At5g15330 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 387
Score = 70.5 bits (171), Expect = 1e-11
Identities = 60/203 (29%), Positives = 92/203 (44%), Gaps = 19/203 (9%)
Query: 1 MKFGKHLEGRQLE-LPEYNGHFINYKALKKLIKQLSV------PAVSSYTNS-------- 45
MKFGK E LPE+ F+ YK LKKL+K PA S + +S
Sbjct: 70 MKFGKEFRTHLEETLPEWRDKFLCYKPLKKLLKYYPYYSADFGPANSDHNDSRPVFADTT 129
Query: 46 NDYMTLDETDESIRYQSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYE 105
N D+ + ++ + SF L ELEK N+FY++KE D ++ L R +
Sbjct: 130 NISSAADDGGVVPGVRPSEDLQGSFVRILNDELEKFNDFYVDKEEDFVIRLQELKERIEQ 189
Query: 106 YKSK-GKLTSKKSIA--YRTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSH 162
K K G+ S+ + IR + ++ L+ + LN G K+LKK+DKR+
Sbjct: 190 VKEKNGEFASESEFSEEMMDIRRDLVTIHGEMVLLKNYSSLNFAGLVKILKKYDKRTGGL 249
Query: 163 AKDFYLATVVSVQPVFTRNEVSK 185
+ +V QP FT +++
Sbjct: 250 LR-LPFTQLVLHQPFFTTEPLTR 271
>7295892 [M] KOG4177 Ankyrin
Length = 342
Score = 69.7 bits (169), Expect = 2e-11
Identities = 66/211 (31%), Positives = 99/211 (46%), Gaps = 15/211 (7%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
++ +D G PL A G T V L++ N L T TPL + H++V K
Sbjct: 57 VDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGT--TPLFFAAQGGHLDVVK 114
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
ILI G +PS GT PL VAC + + + +L+ G + ++D P+
Sbjct: 115 ILIKAGASVDTPSADGGT-----PLFVACQGGHVKIVRELLDCGANVNAHMKDRA--TPV 167
Query: 541 HIVAKMGGGSELIKLLVSYGADPD--EIDGFNKWPPIFYAIQEGHATTVQVLLELGADVF 598
I A+ G ++ LL+ GA+ D IDG P++ A Q G +VLL+ GA+V
Sbjct: 168 FISAQ-NGHRTVLSLLIQAGAEIDIKRIDGAT---PLWIAAQMGQDHICKVLLQNGANVD 223
Query: 599 MKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ +F A +GH +V+ VLL Y N
Sbjct: 224 TVRCDGATPLFKAAHKGHAAVITVLLKYRPN 254
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Query: 505 LNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPD 564
L++A + A +L+ G +++ +D G PL I+A GG + + L+ GADP+
Sbjct: 34 LHMAAMRGDEVALLRVLDSGKVHVD-CKDEDGTTPL-ILAAAGGHTYCVMELLDQGADPN 91
Query: 565 EIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLL 624
P+F+A Q GH V++L++ GA V + +F A GH+ ++ LL
Sbjct: 92 S-RRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELL 150
Query: 625 SYAGN 629
N
Sbjct: 151 DCGAN 155
>7293416 [U] KOG1162 Predicted small molecule transporter
Length = 681
Score = 68.6 bits (166), Expect = 6e-11
Identities = 45/168 (26%), Positives = 78/168 (45%), Gaps = 23/168 (13%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRY 60
MKF +HL PE+ +INY+ +K ++ Y + +++ ++ +
Sbjct: 1 MKFAEHLSAHIT--PEWRKQYINYEEMKAML----------YLAVEEAPSVESVEDDVLK 48
Query: 61 QSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKGKLTSKKSIAY 120
+ +FF ++EL+K+N FY EK A+ KF LN+ + + ++KKS +
Sbjct: 49 RHFANFDENFFHYCDKELKKINTFYSEKLAEATRKFATLNAELKTSIEESERSAKKSKGH 108
Query: 121 -----------RTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDK 157
R ++ +F L L+ + LN TGF K+LKK DK
Sbjct: 109 KRHAALPDRKARELKLAFSEFYLSLILLQNYQNLNHTGFRKILKKHDK 156
>Hs19923272 [U] KOG1162 Predicted small molecule transporter
Length = 696
Score = 67.8 bits (164), Expect = 9e-11
Identities = 54/205 (26%), Positives = 94/205 (45%), Gaps = 32/205 (15%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRY 60
MKF +HL PE+ +I Y+A K ++ Y+ + +++ TDE
Sbjct: 1 MKFAEHLSAHIT--PEWRKQYIQYEAFKDML----------YSAQDQAPSVEVTDEDTVK 48
Query: 61 QSLQENKASFFFKLERELEKVNEFYLEKEADLRMKF-----DLLNSRYYEYKSKG----- 110
+ + + FF E+EL K+N FY EK A+ + +F +L +S + +S G
Sbjct: 49 RYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLR 108
Query: 111 -------KLTSKKSIAYRTIRD---GIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSH 160
L+ ++ + +R I+D +F L L+ + LN TGF K+LKK DK
Sbjct: 109 QRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILE 168
Query: 161 SHAKDFYLATVVSVQPVFTRNEVSK 185
+ + V V P +T ++++
Sbjct: 169 TSRGADWRVAHVEVAPFYTCKKINQ 193
>Hs20538133 [R] KOG0504 FOG: Ankyrin repeat
Length = 899
Score = 67.4 bits (163), Expect = 1e-10
Identities = 52/212 (24%), Positives = 104/212 (48%), Gaps = 15/212 (7%)
Query: 431 PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG-NVN 489
PLH A G + +L+ + L ++D+ +++ +TPL L+ H+E +LI QG ++
Sbjct: 399 PLHLAAYHGHHQALEVLVQSLL--DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 456
Query: 490 LSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDI-NLSRLRDSQGLCPLHIVAKMGG 548
+ + + T P++ A +N + E ++++ + N ++D G PL +++ + G
Sbjct: 457 VKDYILKRT-----PIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPL-MLSVLNG 510
Query: 549 GSELIKLLVSYGADPDEIDGFNKW--PPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
++ + L++ GA+ +D +KW + GH V LL+ GA ++D + +
Sbjct: 511 HTDCVYSLLNKGAN---VDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRT 567
Query: 607 QVFYALWEGHLSVLNVLLSYAGNRKRYSAFPD 638
+ + GH+ VL LL A + A D
Sbjct: 568 PIHLSAACGHIGVLGALLQSAASMDANPATAD 599
Score = 63.5 bits (153), Expect = 2e-09
Identities = 54/215 (25%), Positives = 98/215 (45%), Gaps = 11/215 (5%)
Query: 424 QDIHGRMPLHYACELGKTNFVSLLINT--ELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
+D GR P+H + G + L+ + + N DN T L + N H ++
Sbjct: 561 RDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVEL 620
Query: 482 LIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLH 541
L+ Q + EG F PL+ A N N AA+++++ ++ DS+G PLH
Sbjct: 621 LLEQEVFQKT----EGNA--FSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLH 674
Query: 542 IVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLL-ELGADVFMK 600
A E ++LL+S+ A + +D K P+ A + G TV++L+ A++ ++
Sbjct: 675 -AAAFTDHVECLQLLLSHNAQVNSVDSTGK-TPLMMAAENGQTNTVEMLVSSASAELTLQ 732
Query: 601 DQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSA 635
D + + A +GH + ++L +R +A
Sbjct: 733 DNSKNTALHLACSKGHETSALLILEKITDRNLINA 767
Score = 63.2 bits (152), Expect = 2e-09
Identities = 60/220 (27%), Positives = 96/220 (43%), Gaps = 13/220 (5%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NA D R +H+A +G V LL++ + D S TPL + + I V K
Sbjct: 12 INAFDKKDRRAIHWAAYMGHIEVVKLLVSHGA--EVTCKDKKSYTPLHAAASSGMISVVK 69
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
L+ G P+ T PL+VAC N +++ G I ++ +G PL
Sbjct: 70 YLLDLGVDMNEPNAYGNT-----PLHVACYNGQDVVVNELIDCGAI--VNQKNEKGFTPL 122
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMK 600
H A G+ ++LLV GAD + K P+ G + Q +++ GA + +
Sbjct: 123 HFAAASTHGALCLELLVGNGADVNMKSKDGK-TPLHMTALHGRFSRSQTIIQSGAVIDCE 181
Query: 601 DQQNLSQVFYALWEGHLSVLNVLL-SYAGNRKR--YSAFP 637
D+ + + A GH ++N L+ S A KR + FP
Sbjct: 182 DKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFP 221
Score = 62.4 bits (150), Expect = 4e-09
Identities = 57/181 (31%), Positives = 87/181 (47%), Gaps = 16/181 (8%)
Query: 429 RMPLHYACELGKTNFVSLLI-NTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
R P+H A G + + LLI N E + +D+ D +TPL+LS++N H + L+ +G
Sbjct: 464 RTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGA 523
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
NV+ K L+ + E +L+ G L LRDS+G P+H+ A
Sbjct: 524 NVDAK------DKWGRTALHRGAVTGHEECVDALLQHGAKCL--LRDSRGRTPIHLSAAC 575
Query: 547 GGGSELIKLL---VSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQ 603
G L LL S A+P D + + + +A GH T V++LLE +VF K +
Sbjct: 576 GHIGVLGALLQSAASMDANPATADN-HGYTALHWACYNGHETCVELLLE--QEVFQKTEG 632
Query: 604 N 604
N
Sbjct: 633 N 633
Score = 59.7 bits (143), Expect = 3e-08
Identities = 55/221 (24%), Positives = 97/221 (43%), Gaps = 10/221 (4%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N + +G PLH AC G+ V+ LI+ I ++ + TPL + + H +
Sbjct: 78 MNEPNAYGNTPLHVACYNGQDVVVNELIDCGAI--VNQKNEKGFTPLHFAAASTHGALCL 135
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
L+ +++ +G P L++ + + ++ I++ G + D G PL
Sbjct: 136 ELLVGNGADVNMKSKDGKTP----LHMTALHGRFSRSQTIIQSGAV--IDCEDKNGNTPL 189
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMK 600
HI A+ G LI L++ GAD + G + P+ A G + + LL G D+
Sbjct: 190 HIAARYGH-ELLINTLITSGADTAK-RGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTP 247
Query: 601 DQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
D + + A G+L LN+LL+ + + F PL
Sbjct: 248 DDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPL 288
Score = 57.0 bits (136), Expect = 2e-07
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 8/173 (4%)
Query: 420 LLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVT 479
++NA D GR PLH A + LL++ ++ +D+T KTPL+++ N
Sbjct: 661 IVNATDSKGRTPLHAAAFTDHVECLQLLLSHNA--QVNSVDSTGKTPLMMAAENGQTNTV 718
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEK-GDINLSRLRDSQGLC 538
++L++ + L +L + +K L++ACS + +A +ILEK D NL ++
Sbjct: 719 EMLVSSASAEL--TLQDNSKNT--ALHLACSKGHETSALLILEKITDRNLINATNAALQT 774
Query: 539 PLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLL 591
PLH+ A+ G + +++ L+ GA +D P + A + A + ++L
Sbjct: 775 PLHVAAR-NGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALIL 826
>Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1267
Score = 67.0 bits (162), Expect = 2e-10
Identities = 49/210 (23%), Positives = 99/210 (46%), Gaps = 8/210 (3%)
Query: 432 LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLS 491
L+++ G+ V L++ + N + ++PL + H+++ +L+ Q N+
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLV-QAGANID 769
Query: 492 PSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSE 551
++ Q PL A N + EA K +++ G L +D++G LH+ AK G E
Sbjct: 770 TC----SEDQRTPLMEAAENNHLEAVKYLIKAGA--LVDPKDAEGSTCLHLAAKKGH-YE 822
Query: 552 LIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYA 611
+++ L+S G W P+ +A + H V++LL G+D+ ++D + + +A
Sbjct: 823 VVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWA 882
Query: 612 LWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
+ G + + +LL+ + + D PL
Sbjct: 883 AFSGCVDIAEILLAAKCDLHAVNIHGDSPL 912
>YPL110c_1 [U] KOG1162 Predicted small molecule transporter
Length = 303
Score = 66.2 bits (160), Expect = 3e-10
Identities = 54/204 (26%), Positives = 96/204 (46%), Gaps = 48/204 (23%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYT--NSNDY-------MTL 51
MKFGK ++ PE++ ++ YK+LKK+IK+++ Y N N Y
Sbjct: 1 MKFGKTFANHRI--PEWSSQYVGYKSLKKMIKEITRLQEDIYRAHNKNSYDEGRPPTKMR 58
Query: 52 DETDESIRY---QSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFD--LLNSRYYEY 106
D ++ + Y +Q+ ASFFF ++R++EKV+ FY + A+ + +F+ L ++++ E
Sbjct: 59 DSSNSAQNYLDSPKIQKLLASFFFAVDRDIEKVDTFYNSQYAEYKKRFERLLSSNQFNEI 118
Query: 107 KSKGKLTSKKSIAYRTI-------------------------RDGIKKFERDLAQLEQ-- 139
KS + + K A +D + + + LA+L +
Sbjct: 119 KSTLVVDANKEDAVAQTLLTKDTREMNMLLKGTSQASRLSYHKDDLIEIQSILAELRKQF 178
Query: 140 -----FVELNRTGFSKVLKKWDKR 158
+ ELN+ F K+LKK DK+
Sbjct: 179 RNLKWYAELNKRAFGKILKKLDKK 202
>YGR232w [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 228
Score = 65.9 bits (159), Expect = 4e-10
Identities = 56/197 (28%), Positives = 92/197 (46%), Gaps = 8/197 (4%)
Query: 420 LLNAQDIHGRMPLHYACELGKTNFVSLLINT-ELIDNIDLLDNTSKTPLVLSIINNHIEV 478
LL +D GR+PLH++ S L++ E ++ D D++ TP ++ ++EV
Sbjct: 28 LLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEV 87
Query: 479 TKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLC 538
K L + L P L + T L++A K +E ++ ++E G R++D
Sbjct: 88 VKSLYDRP---LKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGAS--VRIKDKFNQI 142
Query: 539 PLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLE-LGADV 597
PLH A +G +LI+LL G W P+F+A+ EGH +L+E GA+
Sbjct: 143 PLHRAASVGS-LKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEY 201
Query: 598 FMKDQQNLSQVFYALWE 614
+ D + AL E
Sbjct: 202 DLVDNKGAKAEDVALNE 218
>Hs7705831 [R] KOG0504 FOG: Ankyrin repeat
Length = 518
Score = 65.1 bits (157), Expect = 6e-10
Identities = 62/226 (27%), Positives = 102/226 (44%), Gaps = 15/226 (6%)
Query: 415 EAFRKLL------NAQDIHGRMPLHYACELGKTNFVSLLINTELIDN-IDLLDNTSKTPL 467
+ RKLL + D G MP+H A + +LIN + +N I + L
Sbjct: 24 KVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCAL 83
Query: 468 VLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDIN 527
L+ H ++ +IL+ G + +L E T PL +A N + +++L+ G N
Sbjct: 84 HLAASQGHWKIVQILLEAGADPNATTLEETT-----PLFLAVENGQIDVLRLLLQHG-AN 137
Query: 528 LSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTV 587
++ G LH A +E+IKLL+ GA+ + D F P+F A Q G ++
Sbjct: 138 VNGSHSMCGWNSLH-QASFQENAEIIKLLLRKGANKECQDDFGI-TPLFVAAQYGKLESL 195
Query: 588 QVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRY 633
+L+ GA+V + + +F A EGH + +LLS + Y
Sbjct: 196 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLY 241
>Hs6601590 [R] KOG0510 Ankyrin repeat protein
Length = 1119
Score = 65.1 bits (157), Expect = 6e-10
Identities = 54/193 (27%), Positives = 94/193 (47%), Gaps = 10/193 (5%)
Query: 412 IQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSI 471
+Q + ++L+ +D G PLHYAC G V+ L+ + +I K+PL +
Sbjct: 397 MQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNV--SIHSKSKDKKSPLHFAA 454
Query: 472 INNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRL 531
I + L+ +++ + L EG PL++A N + + +++L+KG + LS
Sbjct: 455 SYGRINTCQRLLQ--DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALFLS-- 510
Query: 532 RDSQGLCPLHIVAKMGGGSELIKLLVSYGAD-PDEIDGFNKWPPIFYAIQEGHATTVQVL 590
D G LH A MGG ++ +K+++ D +D + +A +EGHA V +L
Sbjct: 511 -DHNGWTALH-HASMGGYTQTMKVILDTNLKCTDRLDEDGN-TALHFAAREGHAKAVALL 567
Query: 591 LELGADVFMKDQQ 603
L AD+ + QQ
Sbjct: 568 LSHNADIVLNKQQ 580
Score = 57.0 bits (136), Expect = 2e-07
Identities = 47/168 (27%), Positives = 79/168 (46%), Gaps = 14/168 (8%)
Query: 432 LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG-NVNL 490
LHYA G+ + + ++ + +D+ TPL ++ N IE K L+++G N NL
Sbjct: 67 LHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNL 126
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
PL++A N E KV+LE I+++ L G + I+A S
Sbjct: 127 R------NFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVN-LEGENGNTAV-IIACTTNNS 178
Query: 551 ELIKLLVSYGADPDEIDGFNKWP--PIFYAIQEGHATTVQVLLELGAD 596
E +++L++ GA P + NKW PI A G ++++L G +
Sbjct: 179 EALQILLNKGAKPCK---SNKWGCFPIHQAAFSGSKECMEIILRFGEE 223
>7301689 [R] KOG0504 FOG: Ankyrin repeat
Length = 2119
Score = 63.9 bits (154), Expect = 1e-09
Identities = 62/208 (29%), Positives = 101/208 (47%), Gaps = 15/208 (7%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N D G PL A G + V LLI + IDL D +T L + + H ++ K
Sbjct: 1309 VNHADRDGWTPLRSASWGGHSEVVRLLI-AQPACKIDLADKEGRTALRAAAWSGHEDILK 1367
Query: 481 ILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNK-NYEAAKVILEKGDINLSRLRDSQGLC 538
+LI G +VN Q +A S +Y+ +++LE G N++ L D G
Sbjct: 1368 LLIESGADVN-------SVDRQGRTSLIAASYMGHYDIVEILLENG-ANVNHL-DLDGRS 1418
Query: 539 PLHIVAKMG--GGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGAD 596
L + A G G S++I L+ +GA+ D++D + P+ + EG+A ++LLE AD
Sbjct: 1419 ALCVAALCGSSGYSKVISTLLDHGANTDQLDN-DGMSPLLVSSFEGNAEVCELLLENAAD 1477
Query: 597 VFMKDQQNLSQVFYALWEGHLSVLNVLL 624
+ D + ++ A GH +V+ +LL
Sbjct: 1478 PDLADFMGRTPLWAACTAGHATVVKLLL 1505
Score = 60.5 bits (145), Expect = 2e-08
Identities = 68/275 (24%), Positives = 113/275 (40%), Gaps = 42/275 (15%)
Query: 377 LVFARHNMFHEAAL-----------CPHQPRTFVLLAA----------LYQYQNSIIQQE 415
L +A FHE L C ++ +T + LAA L +S + Q+
Sbjct: 1555 LHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGRLHCVQALLDIHSSFVDQK 1614
Query: 416 AFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNH 475
A G+ AC G + V L+ + +++ D S+T L + + N
Sbjct: 1615 AH---------DGKTAFRLACLEGHMDTVEFLL--KFCCDVNSKDADSRTTLYILALENK 1663
Query: 476 IEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDS 534
+E+ K L+ NV+++ EG L+VA + + K ++E G D+N D
Sbjct: 1664 LEIVKYLLDMTNVDVNIPDSEGRTA----LHVAAWQGHADMVKTLIEAGADVNSM---DL 1716
Query: 535 QGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELG 594
+ PLH A G +++ +L+ YGA D + + QEGH V LL+ G
Sbjct: 1717 EARTPLHSCAWQGN-HDVMNILLYYGALADHACKQGA-TALGISAQEGHEKCVIALLQFG 1774
Query: 595 ADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
A+ + D + + A S+L + SY N
Sbjct: 1775 ANPYKSDHCGRTPIKLAAKSSRTSILKIFESYTKN 1809
Score = 55.1 bits (131), Expect = 6e-07
Identities = 56/222 (25%), Positives = 100/222 (44%), Gaps = 21/222 (9%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLIN--------TELIDNIDL--LDNTSKTPLVLS 470
L +D +G+ L+ A G V LL++ T + +D+ D TPL +
Sbjct: 1264 LEIEDYNGQTALNIAARNGHLEVVKLLLSFSQPCNDGTGRMKRVDVNHADRDGWTPLRSA 1323
Query: 471 IINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLS 529
H EV ++LIAQ + + EG L A + + + K+++E G D+N
Sbjct: 1324 SWGGHSEVVRLLIAQPACKIDLADKEGRTA----LRAAAWSGHEDILKLLIESGADVNSV 1379
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAI--QEGHATTV 587
D QG L I A G +++++L+ GA+ + +D + A+ G++ +
Sbjct: 1380 ---DRQGRTSL-IAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVI 1435
Query: 588 QVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
LL+ GA+ D +S + + +EG+ V +LL A +
Sbjct: 1436 STLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAAD 1477
Score = 52.0 bits (123), Expect = 5e-06
Identities = 57/219 (26%), Positives = 95/219 (43%), Gaps = 17/219 (7%)
Query: 415 EAFRKLLNA------QDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLV 468
E R+LL+ +D G PLHYA G L+ + ID DN KT L
Sbjct: 1532 ETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGA--KIDECDNEGKTALH 1589
Query: 469 LSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DIN 527
L+ + + L+ + + +G K F +AC + + + +L+ D+N
Sbjct: 1590 LAAQEGRLHCVQALLDIHSSFVDQKAHDG-KTAFR---LACLEGHMDTVEFLLKFCCDVN 1645
Query: 528 LSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTV 587
+D+ L+I+A + E++K L+ I + A +GHA V
Sbjct: 1646 S---KDADSRTTLYILA-LENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMV 1701
Query: 588 QVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
+ L+E GADV D + + + W+G+ V+N+LL Y
Sbjct: 1702 KTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYY 1740
Score = 51.6 bits (122), Expect = 7e-06
Identities = 43/175 (24%), Positives = 79/175 (44%), Gaps = 29/175 (16%)
Query: 455 NIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNY 514
++++ D +T L ++ N H+EV K+L+ + S +GT
Sbjct: 1263 DLEIEDYNGQTALNIAARNGHLEVVKLLL-----SFSQPCNDGTGR-------------- 1303
Query: 515 EAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPP 574
+++ D+N + D G PL A GG SE+++LL++ A ++
Sbjct: 1304 ------MKRVDVNHA---DRDGWTPLR-SASWGGHSEVVRLLIAQPACKIDLADKEGRTA 1353
Query: 575 IFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ A GH +++L+E GADV D+Q + + A + GH ++ +LL N
Sbjct: 1354 LRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGAN 1408
>Hs22064845 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 722
Score = 63.5 bits (153), Expect = 2e-09
Identities = 61/226 (26%), Positives = 97/226 (41%), Gaps = 24/226 (10%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
++AQ+ G PLH A + N LL++ + N L + KTPL ++ H+ + K
Sbjct: 430 VDAQEREGWTPLHLAAQNNFENVARLLVSRQADPN--LHEAEGKTPLHVAAYFGHVSLVK 487
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
+L +QG L + PL++A A + +L+ G + D G PL
Sbjct: 488 LLTSQG-----AELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAV--PDALDQSGYGPL 540
Query: 541 H--------IVAKM-----GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTV 587
H ++ KM G E+I LL A+ + N W P+ A + G V
Sbjct: 541 HTAAARGKYLICKMLLSLQGPPGEIIHLLAESHANMGALGAVN-WTPLHLAARHGEEAVV 599
Query: 588 QVLLELGADVFMKDQQNLSQVFYALWEG-HLSVLNVLLSYAGNRKR 632
LL+ GAD +Q + + A+ LSV+N+L +A R
Sbjct: 600 SALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHAR 645
Score = 60.1 bits (144), Expect = 2e-08
Identities = 60/243 (24%), Positives = 103/243 (41%), Gaps = 23/243 (9%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
N + G+ PLH A G + V LL T +D +TPL L++ + +
Sbjct: 464 NLHEAEGKTPLHVAAYFGHVSLVKLL--TSQGAELDAQQRNLRTPLHLAVERGKVRAIQH 521
Query: 482 LIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE----KGDI---------NL 528
L+ G V P + + + PL+ A + Y K++L G+I N+
Sbjct: 522 LLKSGAV---PDALD--QSGYGPLHTAAARGKYLICKMLLSLQGPPGEIIHLLAESHANM 576
Query: 529 SRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQ 588
L + PLH+ A+ G + ++ L+ GADP+ + + W P+ A+Q +V
Sbjct: 577 GAL-GAVNWTPLHLAARHGEEA-VVSALLQCGADPNAAEQ-SGWTPLHLAVQRSTFLSVI 633
Query: 589 VLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPS 648
LLE A+V +++ + A +G+ ++L VL+ PL +LR
Sbjct: 634 NLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSR 693
Query: 649 DPG 651
G
Sbjct: 694 KQG 696
>Hs14731279 [R] KOG0504 FOG: Ankyrin repeat
Length = 743
Score = 63.5 bits (153), Expect = 2e-09
Identities = 58/217 (26%), Positives = 99/217 (44%), Gaps = 15/217 (6%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
N D GR+P A + G + V +L+ + NID + L ++ + H ++ ++
Sbjct: 188 NEIDNDGRIPFILASQEGHYDCVQILLENK--SNIDQRGYDGRNALRVAALEGHRDIVEL 245
Query: 482 LIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCP 539
L + G +VN + T L + A+ LE G ++ S D++G
Sbjct: 246 LFSHGADVNCKDADGRPT------LYILALENQLTMAEYFLENGANVEAS---DAEGRTA 296
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH V+ G E++++L++Y AD + D K + A +GH VQ+L+E GA V
Sbjct: 297 LH-VSCWQGHMEMVQVLIAYHADVNAADN-EKRSALQSAAWQGHVKVVQLLIEHGAVVDH 354
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAF 636
Q + + A EGH+ V+ VLL + + F
Sbjct: 355 TCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 391
Score = 60.1 bits (144), Expect = 2e-08
Identities = 59/214 (27%), Positives = 89/214 (41%), Gaps = 16/214 (7%)
Query: 421 LNAQDIHGRMPLHYAC-----ELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNH 475
+N +D+ GR L A G + VSLLI+ +D D TPL+++ H
Sbjct: 17 VNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGA--EVDHCDKDGMTPLLVAAYEGH 74
Query: 476 IEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQ 535
++V +L+ +G ++ + G P L A S + +L G S DS+
Sbjct: 75 VDVVDLLL-EGGADVDHTDNNGRTP----LLAAASMGHASVVNTLLFWGAAVDSI--DSE 127
Query: 536 GLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGA 595
G L I A G E+++ L+ G D + D W P+ A EGH + L+E GA
Sbjct: 128 GRTVLSI-ASAQGNVEVVRTLLDRGLDENHRDDAG-WTPLHMAAFEGHRLICEALIEQGA 185
Query: 596 DVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
D A EGH + +LL N
Sbjct: 186 RTNEIDNDGRIPFILASQEGHYDCVQILLENKSN 219
Score = 55.5 bits (132), Expect = 5e-07
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 13/206 (6%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
N +D G PLH A G LI N +DN + P +L+ H + +I
Sbjct: 155 NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNE--IDNDGRIPFILASQEGHYDCVQI 212
Query: 482 LIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPL 540
L+ + N+ +G + L VA + + +++ G D+N +D+ G L
Sbjct: 213 LL-ENKSNIDQRGYDGR----NALRVAALEGHRDIVELLFSHGADVNC---KDADGRPTL 264
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMK 600
+I+A + + + + GA+ + D + + + +GH VQVL+ ADV
Sbjct: 265 YILA-LENQLTMAEYFLENGANVEASDAEGR-TALHVSCWQGHMEMVQVLIAYHADVNAA 322
Query: 601 DQQNLSQVFYALWEGHLSVLNVLLSY 626
D + S + A W+GH+ V+ +L+ +
Sbjct: 323 DNEKRSALQSAAWQGHVKVVQLLIEH 348
>Hs4885087 [R] KOG0504 FOG: Ankyrin repeat
Length = 446
Score = 63.2 bits (152), Expect = 2e-09
Identities = 57/222 (25%), Positives = 102/222 (45%), Gaps = 12/222 (5%)
Query: 425 DIHGRMPLHYACELGKTNFVSLLINT--ELIDNIDLLDNTSKTPLVLSIINNHIEVTKIL 482
D G PLH A G V L+N + +D+ +N +TPL L++I V ++L
Sbjct: 124 DEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLL 183
Query: 483 IAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEK---GDINLSRLRDSQGLCP 539
+ G SP + + ++AC +++ + +L+ G ++L R+ GL
Sbjct: 184 VTAG---ASPMALD--RHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEA-RNYDGLTA 237
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ E ++LL+ GAD D +D + P+ +A++ + VQ+LL+ GA+V
Sbjct: 238 LHVAVNTEC-QETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNA 296
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
+ S + A G L ++ L+ + + D PL
Sbjct: 297 QMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPL 338
>Hs20472035 [R] KOG0504 FOG: Ankyrin repeat
Length = 361
Score = 63.2 bits (152), Expect = 2e-09
Identities = 71/273 (26%), Positives = 110/273 (40%), Gaps = 66/273 (24%)
Query: 415 EAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINN 474
EA+ + A + + PLH A +G + V L+ +D L TPL+++
Sbjct: 58 EAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA--VDCLKKADWTPLMMACTRK 115
Query: 475 HIEVTKILIAQGNVNLSPS------------------------LCEG-----TKPQFHPL 505
++ V + L+ G L + +C G +K + PL
Sbjct: 116 NLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPL 175
Query: 506 NVACSNKNYEAAKVILEK----------------------GDINLSRL-----------R 532
+ A + + EA KV+L++ G I+++RL
Sbjct: 176 HTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAE 235
Query: 533 DSQGLCPLHIVAKMGGGSELIKLLVS-YGADPDEIDGFNKWPPIFYAIQEGHATTVQVLL 591
DS G LH A + G E I+ LVS G D D + YA +EGH +T+Q LL
Sbjct: 236 DSLGAQALHRAA-VTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLL 294
Query: 592 ELGADVFMKDQQNLSQVFYALWEGHLSVLNVLL 624
LGAD+ KD++N S + A HL+ LL
Sbjct: 295 SLGADINSKDEKNRSALHLACAGQHLACAKFLL 327
>7290442 [U] KOG1162 Predicted small molecule transporter
Length = 649
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/176 (29%), Positives = 78/176 (43%), Gaps = 25/176 (14%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRY 60
MKFGK E E+ ++ Y LK+LIKQ V S S+DY + Y
Sbjct: 1 MKFGKTYESHLTI--EWRQQYMRYGDLKELIKQ-GVENAPSPLTSSDY------EVQAYY 51
Query: 61 QSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYK------------- 107
++ +E +F + + EL VN F+LEK + R K L + Y
Sbjct: 52 KAFEE---TFLTECQSELTGVNNFFLEKLLEARRKHGHLKLQLLAYSREPGHTGSDSSLS 108
Query: 108 SKGKLTSKKSIAYRTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSHA 163
+ + + KK + R +R +F L ++ + LN TGF K+ KK+DK S A
Sbjct: 109 QRAERSQKKLMTTRQLRYAYAEFYLSLVLIQNYQSLNETGFRKICKKYDKNMRSVA 164
>7298635 [U] KOG1162 Predicted small molecule transporter
Length = 599
Score = 62.8 bits (151), Expect = 3e-09
Identities = 53/181 (29%), Positives = 79/181 (43%), Gaps = 30/181 (16%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRY 60
MKFGK L+ L +PE+ ++NY LK++I+ A S SND Y
Sbjct: 1 MKFGKTLDN--LMVPEWRYQYMNYNELKQMIRNAVEKAPSGSRPSNDVAIG-------YY 51
Query: 61 QSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLN----SRYYEYKSKGKLTSKK 116
++ +E FF EL KVN F+ K+A+ K LN R + +G S+
Sbjct: 52 RNFEE---LFFNSCRVELTKVNYFFAHKQAEAHRKLATLNYQLDRRRAQQDPRGSTASRG 108
Query: 117 SIA--------------YRTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSH 162
S + + +R + +F L L+ + LN T F K+ KK+DK S
Sbjct: 109 SASSWSRQPEGKRKFPPIKKLRLAMSEFYLSLIMLQNYQTLNMTAFRKICKKYDKNLKSE 168
Query: 163 A 163
A
Sbjct: 169 A 169
>7295202 [M] KOG4177 Ankyrin
Length = 2443
Score = 62.8 bits (151), Expect = 3e-09
Identities = 67/250 (26%), Positives = 105/250 (41%), Gaps = 45/250 (18%)
Query: 410 SIIQQEAFRKLL-------NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNT 462
S+ QE KLL N Q +G PL+ A + V LL++ N L
Sbjct: 85 SLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGA--NQSLATED 142
Query: 463 SKTPLVLSIINNHIEVTKILI---AQGNVNLSPSLCEGTKPQ------------------ 501
TPL +++ H +V +L+ +G V L P+L K
Sbjct: 143 GFTPLAVAMQQGHDKVVAVLLESDTRGKVRL-PALHIAAKKDDVKAATLLLDNDHNPDVT 201
Query: 502 ----FHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLL 556
F PL++A N A ++++KG D+N S + PLH+ AK G + ++ LL
Sbjct: 202 SKSGFTPLHIASHYGNQNIANLLIQKGADVNYSA---KHNISPLHVAAKWGK-TNMVSLL 257
Query: 557 VSYGADPDEI--DGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWE 614
+ G + + DG P+ A + GH V +LLE GA + K + L+ + A
Sbjct: 258 LEKGGNIEAKTRDGLT---PLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQG 314
Query: 615 GHLSVLNVLL 624
H+ +LL
Sbjct: 315 EHVDAARILL 324
Score = 59.7 bits (143), Expect = 3e-08
Identities = 50/197 (25%), Positives = 86/197 (43%), Gaps = 11/197 (5%)
Query: 427 HGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG 486
+G PLH A + + + L+ + N + TPL LS H E++ +LI
Sbjct: 615 NGHTPLHIAARKNQMDIATTLLEYGALANAE--SKAGFTPLHLSSQEGHAEISNLLIEHK 672
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
P+ K P+++ N A+ ILEK N+ + G PLH+ +
Sbjct: 673 AAVNHPA-----KNGLTPMHLCAQEDNVNVAE-ILEKNGANID-MATKAGYTPLHVASHF 725
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
G + +++ L+ GA+ D + P+ Q+GH V +LLE A+ + +
Sbjct: 726 GQAN-MVRFLLQNGANVDAATSIG-YTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQT 783
Query: 607 QVFYALWEGHLSVLNVL 623
+ A G++SVL+ L
Sbjct: 784 PLHIARKLGYISVLDSL 800
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/203 (27%), Positives = 90/203 (43%), Gaps = 17/203 (8%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
G LH A G+ V LL+ N+ TPL ++ NH V ++L++ G
Sbjct: 77 GNTALHIASLAGQEEVVKLLLEHNASVNVQ--SQNGFTPLYMAAQENHDAVVRLLLSNGA 134
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
N +L+ T+ F PL VA + + V+LE S R L LHI AK
Sbjct: 135 NQSLA------TEDGFTPLAVAMQQGHDKVVAVLLE------SDTRGKVRLPALHIAAKK 182
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
+ LL+ +PD + + + P+ A G+ +L++ GADV + N+S
Sbjct: 183 DD-VKAATLLLDNDHNPD-VTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNIS 240
Query: 607 QVFYALWEGHLSVLNVLLSYAGN 629
+ A G +++++LL GN
Sbjct: 241 PLHVAAKWGKTNMVSLLLEKGGN 263
Score = 56.2 bits (134), Expect = 3e-07
Identities = 55/232 (23%), Positives = 101/232 (42%), Gaps = 16/232 (6%)
Query: 411 IIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLS 470
++Q+EA ++AQ +G PLH AC LL+ + TPL ++
Sbjct: 569 LLQKEAD---VDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATA--KNGHTPLHIA 623
Query: 471 IINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLS 529
N +++ L+ G + + S K F PL+++ + E + +++E K +N
Sbjct: 624 ARKNQMDIATTLLEYGALANAES-----KAGFTPLHLSSQEGHAEISNLLIEHKAAVNHP 678
Query: 530 RLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQV 589
GL P+H+ A+ + + ++L GA+ D + P+ A G A V+
Sbjct: 679 A---KNGLTPMHLCAQEDNVN-VAEILEKNGANIDMATKAG-YTPLHVASHFGQANMVRF 733
Query: 590 LLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
LL+ GA+V + + +GH ++N+LL + N + PL
Sbjct: 734 LLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPL 785
Score = 55.1 bits (131), Expect = 6e-07
Identities = 56/198 (28%), Positives = 89/198 (44%), Gaps = 14/198 (7%)
Query: 429 RMP-LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG- 486
R+P LH A + +LL++ + N D+ + TPL ++ + + +LI +G
Sbjct: 172 RLPALHIAAKKDDVKAATLLLDND--HNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGA 229
Query: 487 NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKM 546
+VN S K PL+VA ++LEKG ++ RD GL PLH A+
Sbjct: 230 DVNYS------AKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRD--GLTPLHCAAR- 280
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
G +++ +L+ GA P N P+ A Q H ++LL A V L+
Sbjct: 281 SGHEQVVDMLLERGA-PISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLT 339
Query: 607 QVFYALWEGHLSVLNVLL 624
+ A GH+ V +LL
Sbjct: 340 ALHVAAHCGHVRVAKLLL 357
Score = 53.1 bits (126), Expect = 2e-06
Identities = 38/140 (27%), Positives = 72/140 (51%), Gaps = 8/140 (5%)
Query: 485 QGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVA 544
+ N++++ S G + L++A + + +L +G I S + +G LHI A
Sbjct: 32 KNNIDINTSNANG----LNALHLASKDGHIHVVSELLRRGAIVDSATK--KGNTALHI-A 84
Query: 545 KMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQN 604
+ G E++KLL+ + A + + N + P++ A QE H V++LL GA+ + +
Sbjct: 85 SLAGQEEVVKLLLEHNASVN-VQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDG 143
Query: 605 LSQVFYALWEGHLSVLNVLL 624
+ + A+ +GH V+ VLL
Sbjct: 144 FTPLAVAMQQGHDKVVAVLL 163
>Hs16159328 [R] KOG0504 FOG: Ankyrin repeat
Length = 683
Score = 62.4 bits (150), Expect = 4e-09
Identities = 53/195 (27%), Positives = 88/195 (44%), Gaps = 10/195 (5%)
Query: 424 QDIHGRMPLHYACELGKTNFVSLLINTELID-NIDLLDNTSKTPLVLSIINNHIEVTKIL 482
+D GR PLHYA G ++S L+ L + + DN TPL + N + ++L
Sbjct: 439 KDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVL 498
Query: 483 IAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHI 542
+ Q + F PL+ A N + A ++L D ++ RD +G PLH
Sbjct: 499 LEQ------KCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLH- 551
Query: 543 VAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELG-ADVFMKD 601
A E ++LL+ + A + +D K + A + G A V +L+ AD+ +KD
Sbjct: 552 AAAFADHVECLQLLLRHSAPVNAVDNSGK-TALMMAAENGQAGAVDILVNSAQADLTVKD 610
Query: 602 QQNLSQVFYALWEGH 616
+ + + A +GH
Sbjct: 611 KDLNTPLHLACSKGH 625
Score = 62.4 bits (150), Expect = 4e-09
Identities = 55/201 (27%), Positives = 97/201 (47%), Gaps = 11/201 (5%)
Query: 429 RMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG-N 487
+ PLH A G + +L+ + L+D +D+ D +T L L+ H E + LI QG +
Sbjct: 275 KSPLHLAAYNGHHQALEVLLQS-LVD-LDIRDEKGRTALDLAAFKGHTECVEALINQGAS 332
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDI-NLSRLRDSQGLCPLHIVAKM 546
+ + ++ + T PL+ + N + +++LE D ++D++G PL ++A
Sbjct: 333 IFVKDNVTKRT-----PLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPL-MLAVA 386
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
G + + LL+ A+ D +D + I GH VQ+LLE + KD + +
Sbjct: 387 YGHIDAVSLLLEKEANVDTVDILG-CTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRT 445
Query: 607 QVFYALWEGHLSVLNVLLSYA 627
+ YA GH + L+ LL A
Sbjct: 446 PLHYAAARGHATWLSELLQMA 466
Score = 58.5 bits (140), Expect = 6e-08
Identities = 64/215 (29%), Positives = 100/215 (45%), Gaps = 12/215 (5%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDN-TSKTPLVLSIINNHIEVT 479
L+ +D GR L A G T V LIN +I + DN T +TPL S+IN H
Sbjct: 300 LDIRDEKGRTALDLAAFKGHTECVEALINQGA--SIFVKDNVTKRTPLHASVINGHTLCL 357
Query: 480 KILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
++L+ + N + K Q PL +A + + +A ++LEK + N+ + D G
Sbjct: 358 RLLLEIAD-NPEAVDVKDAKGQT-PLMLAVAYGHIDAVSLLLEK-EANVDTV-DILGCTA 413
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGA---D 596
LH M G E +++L+ D + P+ YA GHAT + LL++ D
Sbjct: 414 LHR-GIMTGHEECVQMLLEQEVSILCKDSRGR-TPLHYAAARGHATWLSELLQMALSEED 471
Query: 597 VFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRK 631
KD Q + + +A + G+ + + VLL RK
Sbjct: 472 CCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRK 506
Score = 53.9 bits (128), Expect = 1e-06
Identities = 75/302 (24%), Positives = 121/302 (39%), Gaps = 36/302 (11%)
Query: 355 LEVFWKYGNEY-IDLTYSDPDDDLVFARHNMF--HEAALCPHQPRTFVLLAALYQYQNSI 411
L V +YG+E I+ + D H+MF H AAL H LL++ +Y SI
Sbjct: 32 LHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGQKY--SI 89
Query: 412 IQQEAFRKLLNA------QDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKT 465
+ + +L+A D GR LH A G + LL ++ + D +T
Sbjct: 90 VSLFSNEHVLSAGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGA--DFHKKDKCGRT 147
Query: 466 PLVLSIINNHIEVTKILIAQG-NVN-------------------LSPSLCEGTKPQFHPL 505
PL + N H + L+ G NVN + ++ L
Sbjct: 148 PLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEEL 207
Query: 506 NVACSNKNYEAAKVI--LEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADP 563
A K EA + L + D N S +RD +G +H A G L LL +
Sbjct: 208 ERARELKEKEATLCLEFLLQNDANPS-IRDKEGYNSIHYAAAYGHRQCLELLLERTNSGF 266
Query: 564 DEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVL 623
+E D P+ A GH ++VLL+ D+ ++D++ + + A ++GH + L
Sbjct: 267 EESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEAL 326
Query: 624 LS 625
++
Sbjct: 327 IN 328
>7295413 [U] KOG1162 Predicted small molecule transporter
Length = 671
Score = 61.6 bits (148), Expect = 7e-09
Identities = 52/171 (30%), Positives = 79/171 (45%), Gaps = 26/171 (15%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRY 60
MKF +HL PE+ +INY+ +K ++ + S+ + +T RY
Sbjct: 1 MKFAEHLTAHIT--PEWRKQYINYEEMKAMLYAAIEQSPSAELVEREMVT--------RY 50
Query: 61 QSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKG---KLTS--- 114
+ + + FF ++EL K+N FY EK A+ K+ L S E G KL +
Sbjct: 51 FAKFDEE--FFHYCDKELAKINTFYSEKMAEATRKYGSLRSELTEALEMGHPKKLPAWKR 108
Query: 115 -----KKSIAYRTIRD---GIKKFERDLAQLEQFVELNRTGFSKVLKKWDK 157
KK++ R I+D +F L L+ + LN TGF K+LKK DK
Sbjct: 109 RTPLGKKNVPARKIQDLKLAFSEFYLGLILLQNYQNLNFTGFRKILKKHDK 159
>Hs13129098 [R] KOG0504 FOG: Ankyrin repeat
Length = 288
Score = 61.2 bits (147), Expect = 9e-09
Identities = 40/140 (28%), Positives = 74/140 (52%), Gaps = 7/140 (5%)
Query: 504 PLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGAD 562
PL+ AC + + +++LEKG ++N D LH A+ +++L+ YGA+
Sbjct: 56 PLHCACMVSDADCVELLLEKGAEVNAL---DGYNRTALHYAAEKD--EACVEVLLEYGAN 110
Query: 563 PDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNV 622
P+ +DG N+ P+ +A + +A V+ LLE GA V D N + + +A +G+L +++
Sbjct: 111 PNALDG-NRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSI 169
Query: 623 LLSYAGNRKRYSAFPDRPLA 642
LL Y + + P++
Sbjct: 170 LLDYGAEVRVINLIGQTPIS 189
>At2g45130 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 245
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 36/189 (19%)
Query: 1 MKFGKHLEGR-QLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIR 59
MKFGK ++ + Q LPE+ F+ YK LK LI S PA ESI
Sbjct: 1 MKFGKRIKEQIQESLPEWRDKFLRYKELKNLI---SSPAPV---------------ESI- 41
Query: 60 YQSLQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSK---GKLTSKK 116
F L E++K N F++E+E D + L R K S++
Sbjct: 42 ----------FVGLLNAEIDKFNAFFVEQEEDFIIHHKELQYRIQRLVEKCGHNDEMSRE 91
Query: 117 SIAYRTIRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSHAKDFYLATVVSVQP 176
+I+ IR I F ++ L + +N TG +K+LKK+DKR+ + ++ V+ QP
Sbjct: 92 NIS--EIRKDIVNFHGEMVLLVNYSNINYTGLAKILKKYDKRTRGGLRSPFIQKVLH-QP 148
Query: 177 VFTRNEVSK 185
F + VS+
Sbjct: 149 FFKTDLVSR 157
>CE23926 [T] KOG4369 RTK signaling protein MASK/UNC-44
Length = 2584
Score = 60.8 bits (146), Expect = 1e-08
Identities = 51/201 (25%), Positives = 93/201 (45%), Gaps = 11/201 (5%)
Query: 431 PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNL 490
PL AC G + V LL+ NI+ D +PL+++ H V ++L+ N
Sbjct: 1224 PLTIACANGHKDIVELLLKEGA--NIEHRDKKGFSPLIIAATAGHSSVVEVLLK----NH 1277
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
+ + + + L++ACS + +++L G R+ PL + A GG
Sbjct: 1278 AAIEAQSDRTKDTALSLACSGGRKDVVELLLAHG--ANKEHRNVSDYTPLSL-ASSGGYI 1334
Query: 551 ELIKLLVSYGADPDEIDGFNKW-PPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVF 609
E++ +L++ G++ + G P+ A GH +VLLE G+D+ + + N +
Sbjct: 1335 EIVNMLLTAGSEINSRTGSKLGISPLMLASMNGHREATRVLLEKGSDINAQIETNRNTAL 1394
Query: 610 -YALWEGHLSVLNVLLSYAGN 629
A ++G V+ +LL+Y N
Sbjct: 1395 TLASFQGRTEVVKLLLAYNAN 1415
Score = 53.1 bits (126), Expect = 2e-06
Identities = 50/202 (24%), Positives = 90/202 (43%), Gaps = 7/202 (3%)
Query: 424 QDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILI 483
+D G PL A G ++ V +L+ D T T L L+ +V ++L+
Sbjct: 1250 RDKKGFSPLIIAATAGHSSVVEVLLKNHAAIEAQS-DRTKDTALSLACSGGRKDVVELLL 1308
Query: 484 AQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIV 543
A G ++ + T PL++A S E ++L G SR G+ PL ++
Sbjct: 1309 AHGANKEHRNVSDYT-----PLSLASSGGYIEIVNMLLTAGSEINSRTGSKLGISPL-ML 1362
Query: 544 AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQ 603
A M G E ++L+ G+D + N+ + A +G V++LL A+V + +
Sbjct: 1363 ASMNGHREATRVLLEKGSDINAQIETNRNTALTLASFQGRTEVVKLLLAYNANVEHRAKT 1422
Query: 604 NLSQVFYALWEGHLSVLNVLLS 625
L+ + G++ V N+L++
Sbjct: 1423 GLTPLMECASGGYVDVGNLLIA 1444
>CE06305 [T] KOG4369 RTK signaling protein MASK/UNC-44
Length = 2606
Score = 60.8 bits (146), Expect = 1e-08
Identities = 51/201 (25%), Positives = 93/201 (45%), Gaps = 11/201 (5%)
Query: 431 PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNL 490
PL AC G + V LL+ NI+ D +PL+++ H V ++L+ N
Sbjct: 1224 PLTIACANGHKDIVELLLKEGA--NIEHRDKKGFSPLIIAATAGHSSVVEVLLK----NH 1277
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
+ + + + L++ACS + +++L G R+ PL + A GG
Sbjct: 1278 AAIEAQSDRTKDTALSLACSGGRKDVVELLLAHG--ANKEHRNVSDYTPLSL-ASSGGYI 1334
Query: 551 ELIKLLVSYGADPDEIDGFNKW-PPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVF 609
E++ +L++ G++ + G P+ A GH +VLLE G+D+ + + N +
Sbjct: 1335 EIVNMLLTAGSEINSRTGSKLGISPLMLASMNGHREATRVLLEKGSDINAQIETNRNTAL 1394
Query: 610 -YALWEGHLSVLNVLLSYAGN 629
A ++G V+ +LL+Y N
Sbjct: 1395 TLASFQGRTEVVKLLLAYNAN 1415
Score = 53.1 bits (126), Expect = 2e-06
Identities = 50/202 (24%), Positives = 90/202 (43%), Gaps = 7/202 (3%)
Query: 424 QDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILI 483
+D G PL A G ++ V +L+ D T T L L+ +V ++L+
Sbjct: 1250 RDKKGFSPLIIAATAGHSSVVEVLLKNHAAIEAQS-DRTKDTALSLACSGGRKDVVELLL 1308
Query: 484 AQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIV 543
A G ++ + T PL++A S E ++L G SR G+ PL ++
Sbjct: 1309 AHGANKEHRNVSDYT-----PLSLASSGGYIEIVNMLLTAGSEINSRTGSKLGISPL-ML 1362
Query: 544 AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQ 603
A M G E ++L+ G+D + N+ + A +G V++LL A+V + +
Sbjct: 1363 ASMNGHREATRVLLEKGSDINAQIETNRNTALTLASFQGRTEVVKLLLAYNANVEHRAKT 1422
Query: 604 NLSQVFYALWEGHLSVLNVLLS 625
L+ + G++ V N+L++
Sbjct: 1423 GLTPLMECASGGYVDVGNLLIA 1444
>7301132 [R] KOG0504 FOG: Ankyrin repeat
Length = 784
Score = 60.5 bits (145), Expect = 2e-08
Identities = 52/211 (24%), Positives = 95/211 (44%), Gaps = 14/211 (6%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NA G PL +AC G+ + V +L+ N++ + TPL+ + H+EV K
Sbjct: 55 VNAHCATGNTPLMFACAGGQVDVVKVLLKHGA--NVEEQNENGHTPLMEAASAGHVEVAK 112
Query: 481 ILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
+L+ G +N + + L +AC + + + +L+ G + + +
Sbjct: 113 VLLEHGAGIN-----THSNEFKESALTLACYKGHLDMVRFLLQAG---ADQEHKTDEMHT 164
Query: 540 LHIVAKMGGGSELIKLLVSYGADPD-EIDGFNKWPPIFYAIQEGHATTVQVLLELGADVF 598
+ A M G E+ +LL+ GA + D F P+ A GH +L+E GA++
Sbjct: 165 ALMEASMDGHVEVARLLLDSGAQVNMPTDSFES--PLTLAACGGHVELATLLIERGANIE 222
Query: 599 MKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ + + + A EGH ++ +LLS N
Sbjct: 223 EVNDEGYTPLMEAAREGHEEMVALLLSKGAN 253
Score = 57.4 bits (137), Expect = 1e-07
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 13/192 (6%)
Query: 456 IDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYE 515
+++ ++ ++PL L+ H+E+ +LI +G N+ EG + PL A + E
Sbjct: 188 VNMPTDSFESPLTLAACGGHVELATLLIERG-ANIEEVNDEG----YTPLMEAAREGHEE 242
Query: 516 AAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPP 574
++L KG +IN + + L A GG E+ L+ GA+ + P
Sbjct: 243 MVALLLSKGANINATTEETQETALTL---ACCGGFMEVAAFLIKEGANLE----LGASTP 295
Query: 575 IFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYS 634
+ A QEGH V LL+ A+V + Q + + +A GH VLLSY + S
Sbjct: 296 LMEASQEGHTDLVSFLLKKKANVHAETQTGDTALTHACENGHTDAAGVLLSYGAELEHES 355
Query: 635 AFPDRPLAGSLR 646
PL + R
Sbjct: 356 EGGRTPLMKACR 367
Score = 55.5 bits (132), Expect = 5e-07
Identities = 53/200 (26%), Positives = 83/200 (41%), Gaps = 12/200 (6%)
Query: 431 PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNL 490
PL A G + V LL+N N T TPL+ + ++V K+L+ G
Sbjct: 32 PLMEAASAGHLDIVKLLLNHNADVNAHCA--TGNTPLMFACAGGQVDVVKVLLKHG---- 85
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGG 549
++ E + PL A S + E AKV+LE G IN + L A G
Sbjct: 86 -ANVEEQNENGHTPLMEAASAGHVEVAKVLLEHGAGINTHSNEFKESALTL---ACYKGH 141
Query: 550 SELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVF 609
++++ L+ GAD + + A +GH ++LL+ GA V M S +
Sbjct: 142 LDMVRFLLQAGADQEHKTD-EMHTALMEASMDGHVEVARLLLDSGAQVNMPTDSFESPLT 200
Query: 610 YALWEGHLSVLNVLLSYAGN 629
A GH+ + +L+ N
Sbjct: 201 LAACGGHVELATLLIERGAN 220
Score = 54.7 bits (130), Expect = 8e-07
Identities = 50/190 (26%), Positives = 85/190 (44%), Gaps = 9/190 (4%)
Query: 435 ACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSL 494
AC G +L+ D S TPL+ + H+++ K+L+ N +++
Sbjct: 2 ACSAGYYELAQVLLAMSAAQVEDKGQKDS-TPLMEAASAGHLDIVKLLLNH-NADVNAHC 59
Query: 495 CEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIK 554
G P L AC+ + KV+L+ G N+ ++ G PL + A G E+ K
Sbjct: 60 ATGNTP----LMFACAGGQVDVVKVLLKHG-ANVEE-QNENGHTPL-MEAASAGHVEVAK 112
Query: 555 LLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWE 614
+L+ +GA + K + A +GH V+ LL+ GAD K + + + A +
Sbjct: 113 VLLEHGAGINTHSNEFKESALTLACYKGHLDMVRFLLQAGADQEHKTDEMHTALMEASMD 172
Query: 615 GHLSVLNVLL 624
GH+ V +LL
Sbjct: 173 GHVEVARLLL 182
>At4g22990_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 229
Score = 59.7 bits (143), Expect = 3e-08
Identities = 48/169 (28%), Positives = 81/169 (47%), Gaps = 27/169 (15%)
Query: 3 FGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRYQS 62
FGK L+ R ++ E+ G++INYK +KK +KQ Y E R
Sbjct: 4 FGKKLKERSIQ--EWQGYYINYKLMKKKVKQ--------------YSRQLEGGNLERRHV 47
Query: 63 LQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKGKLTSKKSIAYRT 122
L++ F L+ ++EK+ F LE++ L + L S L + I++ +
Sbjct: 48 LKD----FSRMLDNQIEKIALFMLEQQGLLASRLQTLRG------SHDALQEQPDISHMS 97
Query: 123 -IRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSHAKDFYLAT 170
+++ + +DL +L FVE+N G K+LKK+DKR ++Y+ T
Sbjct: 98 YLKEEYRAVGQDLLKLLFFVEMNAIGIRKILKKFDKRFGYRFTNYYVKT 146
>Hs13376003 [M] KOG4177 Ankyrin
Length = 274
Score = 59.3 bits (142), Expect = 3e-08
Identities = 47/154 (30%), Positives = 73/154 (46%), Gaps = 16/154 (10%)
Query: 411 IIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLS 470
+++ E ++NA+ G PLH A G+ +FV LL+ E +D L + TPL L+
Sbjct: 100 MLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLL--EFKAEVDPLSDKGTTPLQLA 157
Query: 471 IINNHIEVTKILI-AQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINL 528
II KIL+ N+++ L A N+ ++ L++G D NL
Sbjct: 158 IIREKSSCVKILLDHNANIDIQNGFL---------LRYAVIKSNHSYCRMFLQRGADTNL 208
Query: 529 SRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGAD 562
RL D Q PLH+ A + ++L +YGAD
Sbjct: 209 GRLEDGQ--TPLHLSA-LRDDVLCARMLYNYGAD 239
>Hs4758818 [T] KOG1217 Fibrillins and related proteins containing Ca2+-binding
EGF-like domains
Length = 2003
Score = 58.9 bits (141), Expect = 4e-08
Identities = 56/212 (26%), Positives = 87/212 (40%), Gaps = 10/212 (4%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G PLH A + L+ E N + D +TPL ++ + EV ++L+
Sbjct: 1634 GETPLHLAARFSRPTAARRLL--EAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQ 1691
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMG 547
+ +GT P +A + E +I + D+ RD G LH A +
Sbjct: 1692 TAVDARTEDGTTPLMLAARLAVEDLVEE---LIAAQADVGA---RDKWGKTALHWAAAVN 1745
Query: 548 GGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQ 607
+ + L+ GAD D D + P+F A +EG Q+LL LGA ++DQ L+
Sbjct: 1746 N-ARAARSLLQAGADKDAQDN-REQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAP 1803
Query: 608 VFYALWEGHLSVLNVLLSYAGNRKRYSAFPDR 639
A H +L +L R+ A P R
Sbjct: 1804 ADVAHQRNHWDLLTLLEGAGPPEARHKATPGR 1835
>Hs18640738 [R] KOG0504 FOG: Ankyrin repeat
Length = 475
Score = 58.9 bits (141), Expect = 4e-08
Identities = 55/187 (29%), Positives = 88/187 (46%), Gaps = 17/187 (9%)
Query: 456 IDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSLCEGT-------KPQFHPLNVA 508
I LD TS+ L I E K + G+V+L L + + + PL A
Sbjct: 27 IGYLDRTSQKLKRLLPIEEKKEKFKKAMTIGDVSLVQELLDSGISVDSNFQYGWTPLMYA 86
Query: 509 CSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSE-----LIKLLVSYGADP 563
S N E +V+L++G N S +D Q + I A GSE ++LL+S ADP
Sbjct: 87 ASVANAELVRVLLDRG-ANASFEKDKQSIL---ITACSAHGSEEQILKCVELLLSRNADP 142
Query: 564 DEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVL 623
+ + PI YA ++GH V +L+ GA+V +D+ + + +A +GH +++ L
Sbjct: 143 N-VACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKL 201
Query: 624 LSYAGNR 630
L N+
Sbjct: 202 LELGANK 208
>Hs16076877 [R] KOG0504 FOG: Ankyrin repeat
Length = 1101
Score = 58.9 bits (141), Expect = 4e-08
Identities = 61/254 (24%), Positives = 97/254 (38%), Gaps = 61/254 (24%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
++A G PL YA G + V LL +D LD + LV + + H+EV K
Sbjct: 12 VDASSESGLTPLGYAAAAGYLSIVVLLCKKRA--KVDHLDKNGQCALVHAALRGHLEVVK 69
Query: 481 IL--------------------------------------------------IAQGNVNL 490
L + + +N
Sbjct: 70 FLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINS 129
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
SL T L A E +++LE+G R +G PL + G
Sbjct: 130 FDSLWGETA-----LTAAAGRGKLEVCRLLLEQGAAVAQPNR--RGAVPLFSTVRQGHW- 181
Query: 551 ELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFY 610
+++ LL+++GAD + D + P+ A EGH TV LL GA + + D++ L+ + +
Sbjct: 182 QIVDLLLTHGADVNMADKQGR-TPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSW 240
Query: 611 ALWEGHLSVLNVLL 624
A +GHLSV+ L+
Sbjct: 241 ACLKGHLSVVRSLV 254
>Hs13386462 [R] KOG0504 FOG: Ankyrin repeat
Length = 435
Score = 58.9 bits (141), Expect = 4e-08
Identities = 53/211 (25%), Positives = 96/211 (45%), Gaps = 14/211 (6%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N+Q G L YAC G + V +L+N NI+ + TPL+ + H+EV +
Sbjct: 106 VNSQSATGNTALTYACAGGFVDIVKVLLNEGA--NIEDHNENGHTPLMEAASAGHVEVAR 163
Query: 481 ILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCP 539
+L+ G +N + + + L +AC + + + +LE G + + +
Sbjct: 164 VLLDHGAGINTHSNEFKESA-----LTLACYKGHLDMVRFLLEAG---ADQEHKTDEMHT 215
Query: 540 LHIVAKMGGGSELIKLLVSYGADPD-EIDGFNKWPPIFYAIQEGHATTVQVLLELGADVF 598
+ A M G E+ +LL+ GA + D F P+ A GH +L+E GA++
Sbjct: 216 ALMEACMDGHVEVARLLLDSGAQVNMPADSFES--PLTLAACGGHVELAALLIERGANLE 273
Query: 599 MKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+ + + + A EGH ++ +LL+ N
Sbjct: 274 EVNDEGYTPLMEAAREGHEEMVALLLAQGAN 304
Score = 57.8 bits (138), Expect = 1e-07
Identities = 55/191 (28%), Positives = 86/191 (44%), Gaps = 15/191 (7%)
Query: 435 ACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSL 494
AC G LL+++ +++ ++ ++PL L+ H+E+ +LI +G NL
Sbjct: 220 ACMDGHVEVARLLLDSGA--QVNMPADSFESPLTLAACGGHVELAALLIERG-ANLEEVN 276
Query: 495 CEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELI 553
EG + PL A + E ++L +G +IN + L A GG SE+
Sbjct: 277 DEG----YTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTL---ACCGGFSEVA 329
Query: 554 KLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALW 613
L+ GAD + P+ A QEGH V+ LL GA+V + + YA
Sbjct: 330 DFLIKAGADIE----LGCSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACE 385
Query: 614 EGHLSVLNVLL 624
GH V +VLL
Sbjct: 386 NGHTDVADVLL 396
Score = 51.2 bits (121), Expect = 9e-06
Identities = 57/216 (26%), Positives = 91/216 (41%), Gaps = 17/216 (7%)
Query: 416 AFRKLL------NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSK-TPLV 468
A RKLL N G L AC G +L+ N++ N TPL+
Sbjct: 28 AVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHA--NVEDRGNKGDITPLM 85
Query: 469 LSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINL 528
+ ++++ K+L+ S S T L AC+ + KV+L +G N+
Sbjct: 86 AASSGGYLDIVKLLLLHDADVNSQSATGNTA-----LTYACAGGFVDIVKVLLNEG-ANI 139
Query: 529 SRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQ 588
+ G PL + A G E+ ++L+ +GA + K + A +GH V+
Sbjct: 140 ED-HNENGHTPL-MEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 197
Query: 589 VLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLL 624
LLE GAD K + + + A +GH+ V +LL
Sbjct: 198 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLL 233
>Hs14738291 [R] KOG0504 FOG: Ankyrin repeat
Length = 1554
Score = 58.5 bits (140), Expect = 6e-08
Identities = 60/217 (27%), Positives = 96/217 (43%), Gaps = 15/217 (6%)
Query: 417 FRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHI 476
F L+ +G L YA G V LL + +D LD + LV S + H
Sbjct: 650 FGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGV--RVDHLDKKGQCALVHSALRGHG 707
Query: 477 EVTKILIAQGNVNLSPSLCE-GTKPQFHPLN----VACSNKNYEAAKVIL---EKGDINL 528
++ + L+ SP + GT + H L A S + + +L ++ ++ +
Sbjct: 708 DILQYLLT---CEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEV 764
Query: 529 SRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQ 588
+ G L A G E+ +LL+ +GA + PP+F A ++GH V+
Sbjct: 765 NGTDTLWGETALTAAAGRGK-LEVCELLLGHGAAVSRTNRRGV-PPLFCAARQGHWQIVR 822
Query: 589 VLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLS 625
+LLE G DV + D+Q + + A EGHLS + LLS
Sbjct: 823 LLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLS 859
>Hs18252778 [R] KOG0504 FOG: Ankyrin repeat
Length = 587
Score = 57.8 bits (138), Expect = 1e-07
Identities = 54/206 (26%), Positives = 90/206 (43%), Gaps = 12/206 (5%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G +PLH A G+ + +L ID +T + L+ H++ L+ G
Sbjct: 90 GWLPLHEAAYYGQVGCLKVL-QRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAG- 147
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLSRLRDSQGLCPLHIVAKM 546
P + K + PL AC KN EA K++++ D N R ++G LH
Sbjct: 148 --AEPDI--SNKSRETPLYKACERKNAEAVKILVQHNADTNH---RCNRGWTALHESVSR 200
Query: 547 GGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLS 606
E++++LVS GA + + + P+F A Q G ++ L + GAD+ + N S
Sbjct: 201 ND-LEVMQILVSGGAKVESKNAYGI-TPLFVAAQSGQLEALRFLAKYGADINTQASDNAS 258
Query: 607 QVFYALWEGHLSVLNVLLSYAGNRKR 632
++ A H V+ LLS + +
Sbjct: 259 ALYEACKNEHEEVVEFLLSQGADANK 284
>CE07175 [R] KOG0508 Ankyrin repeat protein
Length = 656
Score = 57.8 bits (138), Expect = 1e-07
Identities = 57/206 (27%), Positives = 90/206 (43%), Gaps = 17/206 (8%)
Query: 425 DIHGRMPLHYACELGKTNFVSLLINTEL---IDNIDLLDNTS---KTPLVLSIINNHIEV 478
D GR PL A G N V L+ + + DN + PL + HIE+
Sbjct: 45 DQDGRYPLVIAARNGHANVVEYLLEIGADPSVRGVVEFDNENIQGTPPLWAASAAGHIEI 104
Query: 479 TKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGL 537
K+LI + N +++ + T + PL AC + + + K +LEKG D ++ L
Sbjct: 105 VKLLIEKANADVN----QATNTRSTPLRGACYDGHLDIVKYLLEKGADPHIPNRHGHTCL 160
Query: 538 CPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADV 597
K+G EL+K + + + + A + G+ V++LL+ G+ V
Sbjct: 161 MIASYRNKVGIVEELLKTGIDVNKKTERGN-----TALHDAAESGNVEVVKILLKHGS-V 214
Query: 598 FMKDQQNLSQVFYALWEGHLSVLNVL 623
MKD Q + + A G L VLNVL
Sbjct: 215 LMKDIQGVDPLMGAALSGFLDVLNVL 240
>Hs4507613 [M] KOG4177 Ankyrin
Length = 1327
Score = 57.4 bits (137), Expect = 1e-07
Identities = 61/229 (26%), Positives = 97/229 (41%), Gaps = 34/229 (14%)
Query: 421 LNAQDIHGRM--PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEV 478
+NA+D+ GR PLH+A G+ + V L+ ++ N+ D+ PL + H EV
Sbjct: 207 VNAKDMAGRKSSPLHFAAGFGRKDVVEHLL--QMGANVHARDDGGLIPLHNACSFGHAEV 264
Query: 479 TKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGL 537
+L+ QG P+ + + PL+ A + V+L+ G D N+ R++ G
Sbjct: 265 VSLLLCQG---ADPNARDNWN--YTPLHEAAIKGKIDVCIVLLQHGADPNI---RNTDGK 316
Query: 538 CPLHIV--------------------AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFY 577
L + A+ G +L+ LL + DG K P+
Sbjct: 317 SALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDG-RKSTPLHL 375
Query: 578 AIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
A VQ+LL+ GADV KD+ L + A GH V +LL +
Sbjct: 376 AAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH 424
Score = 56.2 bits (134), Expect = 3e-07
Identities = 59/238 (24%), Positives = 101/238 (41%), Gaps = 34/238 (14%)
Query: 412 IQQEAFRKLLNAQDIHGR--MPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVL 469
++Q + +N +D+ GR PLH+A + + V L++ ++ D PL
Sbjct: 666 VKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGA--DVHAKDKGGLVPLHN 723
Query: 470 SIINNHIEVTKILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINL 528
+ H EV ++L+ G +VN++ +F PL+ A + YE K++L+ G
Sbjct: 724 ACSYGHYEVAELLVRHGASVNVADLW------KFTPLHEAAAKGKYEICKLLLKHGADPT 777
Query: 529 SRLRDSQGLCPLHIV--------------------AKMGGGSELIKLLVSYGADPDEIDG 568
+ RD G PL +V AK G + + KL + + G
Sbjct: 778 KKNRD--GNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQG 835
Query: 569 FNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
N P+ A + + LLE GADV +D+ L + A GH+ + +L+ Y
Sbjct: 836 RNS-TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKY 892
>Hs22062923 [R] KOG0504 FOG: Ankyrin repeat
Length = 794
Score = 57.4 bits (137), Expect = 1e-07
Identities = 57/226 (25%), Positives = 102/226 (44%), Gaps = 9/226 (3%)
Query: 401 LAALYQYQNSIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLD 460
LAA + + ++ F +NAQD GR P+H A + LL++ I ++++ D
Sbjct: 401 LAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDI-HLNVRD 459
Query: 461 NTSKTPLVLSI-INNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKV 519
TP ++ N+ IL + + + F L+VA N + E+
Sbjct: 460 RQGLTPFACAMTFKNNKSAEAILKRESG---AAEQVDNKGRNF--LHVAVQNSDIESVLF 514
Query: 520 ILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAI 579
++ SR++D+ L PLH+ A G +++ L+ GA +E+ ++ + A
Sbjct: 515 LISVHANVNSRVQDASKLTPLHL-AVQAGSEIIVRNLLLAGAKVNELTK-HRQTALHLAA 572
Query: 580 QEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLS 625
Q+ T VLLE G D D+ + + A+ G L+ + VLL+
Sbjct: 573 QQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLT 618
>7301359 [M] KOG4177 Ankyrin
Length = 1181
Score = 57.4 bits (137), Expect = 1e-07
Identities = 59/231 (25%), Positives = 92/231 (39%), Gaps = 32/231 (13%)
Query: 421 LNAQDIHGRM--PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEV 478
+NA+D GR PLH+A G+ V L+N+ +I D PL H EV
Sbjct: 48 VNARDTAGRKSTPLHFAAGYGRREVVEFLLNSGA--SIQACDEGGLHPLHNCCSFGHAEV 105
Query: 479 TKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLC 538
++L+ G SP+ + + PL+ A S + +L+ G + +R+S+
Sbjct: 106 VRLLLKAG---ASPNTTDNWN--YTPLHEAASKGKVDVCLALLQHGANHT--IRNSEQKT 158
Query: 539 PLHIV--------------------AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYA 578
PL + A+ G L+ LL + DG + P+ A
Sbjct: 159 PLELADEATRPVLTGEYRKDELLEAARSGAEDRLLALLTPLNVNCHASDG-RRSTPLHLA 217
Query: 579 IQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
V++LL GADV KD+ L + A GH V +L+ N
Sbjct: 218 AGYNRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFDVTKLLIQAGAN 268
Score = 57.0 bits (136), Expect = 2e-07
Identities = 58/227 (25%), Positives = 96/227 (41%), Gaps = 30/227 (13%)
Query: 421 LNAQDIHGR--MPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEV 478
+N +D+ GR PLH+A + V L+ E + D PL + H EV
Sbjct: 511 VNCRDLDGRHSTPLHFAAGFNRVPVVQFLL--EHGAEVYAADKGGLVPLHNACSYGHYEV 568
Query: 479 TKILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDS--- 534
T++L+ G NVN+S +F PL+ A + Y+ K++L+ G + + RD
Sbjct: 569 TELLVKHGANVNVSDLW------KFTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATP 622
Query: 535 ---------------QGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAI 579
+G L AK G + + +L+ + + G N P+ A
Sbjct: 623 ADLVKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPESINCRDAQGRNS-TPLHLAA 681
Query: 580 QEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
+ + LLE GADV +D+ L + A GHL + +L+ +
Sbjct: 682 GYNNFECAEYLLENGADVNAQDKGGLIPLHNASSYGHLDIAALLIKH 728
Score = 51.6 bits (122), Expect = 7e-06
Identities = 53/205 (25%), Positives = 88/205 (42%), Gaps = 24/205 (11%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N D+ PLH A GK + LL+ D + LV ++ E+ +
Sbjct: 579 VNVSDLWKFTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHDVAELLR 638
Query: 481 ----ILIAQGNVNL----------SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-D 525
+L A NL S + + PL++A N+E A+ +LE G D
Sbjct: 639 GPSALLDAAKKGNLARVQRLVTPESINCRDAQGRNSTPLHLAAGYNNFECAEYLLENGAD 698
Query: 526 INLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKW--PPIFYAIQEGH 583
+N +D GL PLH + G ++ LL+ + ++ +KW P+ A Q+G
Sbjct: 699 VNA---QDKGGLIPLHNASSYGH-LDIAALLIKHKT---VVNATDKWGFTPLHEAAQKGR 751
Query: 584 ATTVQVLLELGADVFMKDQQNLSQV 608
+LL GAD +MK+Q+ + +
Sbjct: 752 TQLCSLLLAHGADAYMKNQEGQTPI 776
>At4g11810_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 252
Score = 57.4 bits (137), Expect = 1e-07
Identities = 46/168 (27%), Positives = 81/168 (47%), Gaps = 25/168 (14%)
Query: 3 FGKHLEGRQLELPEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRYQS 62
FGK L+ R +E E+ ++INYK +KK +KQ Y + +LD R
Sbjct: 4 FGKKLKERSIE--EWQEYYINYKLMKKKVKQ--------YGPQIEVGSLD------RRHV 47
Query: 63 LQENKASFFFKLERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKGKLTSKKSIAYRT 122
L++ F L+ ++EK+ F LE++ L + L + + + L+
Sbjct: 48 LKD----FSRMLDHQIEKIALFMLEQQGLLSSRLQKLREWHDTLQDEPDLSQ-----IAK 98
Query: 123 IRDGIKKFERDLAQLEQFVELNRTGFSKVLKKWDKRSHSHAKDFYLAT 170
+R+ + +DL +L F+++N G K+LKK+DKR ++Y+ T
Sbjct: 99 LREAYRAVGQDLLKLLFFIDMNAIGIRKILKKFDKRFGYRFTNYYVKT 146
>7297920 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 585
Score = 57.0 bits (136), Expect = 2e-07
Identities = 53/214 (24%), Positives = 92/214 (42%), Gaps = 10/214 (4%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
L+A+D HG P H+ G + LI ++ L P+ + H V +
Sbjct: 114 LSARDRHGYTPAHWIALNGNVQLMRYLIERTAPIDLPCLGTQGPRPIHWACRKGHASVVQ 173
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
+L+ Q V ++ + +G PL++AC A +L G +N L D G L
Sbjct: 174 VLL-QAGVAVNAADFKG----LTPLHLACMYGRTATAAYLLGMGALN--NLTDINGDTAL 226
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELG-ADVFM 599
H A G ++L++LL+ G + + D F P+ A G+ T V++L E D+
Sbjct: 227 HWAA-YKGHADLMRLLMYSGVELQKTDNFGS-TPLHLACLSGNMTCVRLLCEKSQLDLEP 284
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRY 633
+D+ + + A H V+ +L + R+
Sbjct: 285 RDKNGKTPIMLAQAHQHQDVVRLLYGEVKKKSRW 318
Score = 52.8 bits (125), Expect = 3e-06
Identities = 43/154 (27%), Positives = 76/154 (48%), Gaps = 15/154 (9%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+NA D G PLH AC G+T + L+ ++N L D T L + H ++ +
Sbjct: 182 VNAADFKGLTPLHLACMYGRTATAAYLLGMGALNN--LTDINGDTALHWAAYKGHADLMR 239
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
+L+ G V L + G+ PL++AC + N +++ EK ++L RD G P+
Sbjct: 240 LLMYSG-VELQKTDNFGST----PLHLACLSGNMTCVRLLCEKSQLDLEP-RDKNGKTPI 293
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPP 574
++A+ ++++LL YG E+ ++W P
Sbjct: 294 -MLAQAHQHQDVVRLL--YG----EVKKKSRWIP 320
>YFL004w_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 675
Score = 56.6 bits (135), Expect = 2e-07
Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 21/143 (14%)
Query: 15 PEYNGHFINYKALKKLIKQLSVPAVSSYTNSNDYMTLDETDESIRYQSLQENKASFFFKL 74
P + G +INY+ LKK +K+ SV S+ D+ R+ E+K F +L
Sbjct: 13 PPWKGSYINYEGLKKFLKEDSVKDGSN-------------DKKARWDDSDESK--FVEEL 57
Query: 75 ERELEKVNEFYLEKEADLRMKFDLLNSRYYEYKSKGKLTSKKSIAYRTIRDGIKKFERDL 134
++ELEKV F L+K +L + L + ++ + + + A++ + +++ +
Sbjct: 58 DKELEKVYGFQLKKYNNLMERLSHLEK---QTDTEAAIKALDADAFQRV---LEELLSES 111
Query: 135 AQLEQFVELNRTGFSKVLKKWDK 157
+L+ F LN TGF+K++KK DK
Sbjct: 112 TELDNFKRLNFTGFAKIVKKHDK 134
>Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 835
Score = 56.2 bits (134), Expect = 3e-07
Identities = 56/237 (23%), Positives = 93/237 (38%), Gaps = 16/237 (6%)
Query: 401 LAALYQYQNSIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLD 460
+AA Y ++ F +N G PLH A G N LL+ +++ D
Sbjct: 173 IAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQD 232
Query: 461 NTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVI 520
N PL H ++ K L+ Q ++ + P + PL++AC N +E AK I
Sbjct: 233 NEDHVPLHFCSRFGHHDIVKYLL-QSDLEVQPHVVNIYGDT--PLHLACYNGKFEVAKEI 289
Query: 521 LEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQ 580
++ + H G +L+K L+ G + + A
Sbjct: 290 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 349
Query: 581 EGHATTVQVLLELGADVFM-----------KDQQNLSQVFYALWEGHLSVLNVLLSY 626
GH VQ LL+ GAD+ + KD+Q + +A +GH +++ +L Y
Sbjct: 350 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTC--LMWAYEKGHDAIVTLLKHY 404
>Hs7705278_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 860
Score = 56.2 bits (134), Expect = 3e-07
Identities = 53/206 (25%), Positives = 94/206 (44%), Gaps = 9/206 (4%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N QD GR P H A + LL++ I ++++ D TP ++ + +
Sbjct: 487 VNPQDAEGRTPCHVAISSQHGVIIQLLVSHP-ISSLNVRDKQGLTPFACAMTFKDNKSAE 545
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAA-KVILEKGDINLSRLRDSQGLCP 539
++ +G+ +G + L+VA N + E+ +I ++N SR +D+ L P
Sbjct: 546 AILKRGSGAAEQVDNKGR----NSLHVAVQNSDIESVLSLISVHANVN-SRAQDAPKLTP 600
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+V + G +++ L+ GA E+ K + A QE T VLLE D
Sbjct: 601 LHLVVQEGS-EIIVRNLLLAGAKVTELTKHRK-TALHLAAQEDLPTICSVLLENAVDFAA 658
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLS 625
D+ + + A+ G L+ + VLL+
Sbjct: 659 VDENGNNALHLAVMHGRLNNIRVLLT 684
>CE19142 [U] KOG1162 Predicted small molecule transporter
Length = 710
Score = 55.5 bits (132), Expect = 5e-07
Identities = 47/176 (26%), Positives = 76/176 (42%), Gaps = 37/176 (21%)
Query: 1 MKFGKHLEGRQLELPEYNGHFINYKALKKLI--KQLSVPAVSSYTNSNDYMTLDETDESI 58
MKFG+ L PE+ +I+Y+ LK L+ + VPA D+
Sbjct: 1 MKFGEQLASHLT--PEWRKQYIDYERLKNLLYDDMMEVPA----------------DDDR 42
Query: 59 RYQSLQENKASFFFKLERELEKVNEFYLEK-----------EADLRMKFDLLNSRYYEYK 107
R + + FF + ++EL K+N F+ +K + +L++ D+L SR
Sbjct: 43 REEHISRLDEKFFNECDQELTKINLFFSQKIAEGQGKHHELQTELQVFKDVLGSRSDTTG 102
Query: 108 SKGKLTSKKSIAYRTIRD------GIKKFERDLAQLEQFVELNRTGFSKVLKKWDK 157
+ + K T R+ +F L ++ F +LN TGF K+LKK DK
Sbjct: 103 IRRRFGGKDKFHKETTRNEQQLKLAFSEFYLSLVLVQNFQQLNATGFRKILKKHDK 158
>Hs4557349_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 162
Score = 55.1 bits (131), Expect = 6e-07
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 2/115 (1%)
Query: 527 NLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATT 586
N++ R+ +G LHI A + G ++ L+ G+DP+ D W P+ A GH
Sbjct: 10 NMAVKRNHRGETLLHI-ASIKGDIPSVEYLLQNGSDPNVKDHAG-WTPLHEACNHGHLKV 67
Query: 587 VQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
V++LL+ A V QN S + A GH+ ++ +LLSY +R + F RP+
Sbjct: 68 VELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPV 122
>CE26238_1 [M] KOG4177 Ankyrin
Length = 1294
Score = 55.1 bits (131), Expect = 6e-07
Identities = 53/217 (24%), Positives = 96/217 (43%), Gaps = 22/217 (10%)
Query: 422 NAQD--IHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPL----VLSIINNH 475
NA+D HG LH K F+S+L E D I + KT L + + N
Sbjct: 1071 NAEDENSHGMTALHLGA---KNGFISIL---EAFDKILWKRCSRKTGLNALHIAAFYGNS 1124
Query: 476 IEVTKILI-AQGNVNLSPSLCE-------GTKPQFHPLNVACSNKNYEAAKVILEKGDIN 527
V ++L Q V P + T+ F PL++A + + +++L +G +
Sbjct: 1125 DFVNEMLKHVQATVRSEPPIYNHHVNKEFSTEYGFTPLHLAAQSGHDSLVRMLLNQG-VQ 1183
Query: 528 LSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTV 587
+ + + PLH+ A+ G + ++ +L+S + P+ A Q GH V
Sbjct: 1184 VDATSTTMNVIPLHLAAQQGHIA-VVGMLLSRSTQQQHAKDWRGRTPLHLAAQNGHYEMV 1242
Query: 588 QVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLL 624
+L+ G+++ + DQ + + +A GHLSV+ + +
Sbjct: 1243 SLLIAQGSNINVMDQNGWTGLHFATRAGHLSVVKLFI 1279
Score = 54.7 bits (130), Expect = 8e-07
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 13/210 (6%)
Query: 423 AQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKIL 482
A+D G +P+H A + G N V LL++ + D T L L+ + +IE +
Sbjct: 405 AEDGDGSLPIHLAFKFGNVNIVELLLSGPSDEQTRKADGNGDTLLHLAARSGNIEAVRTA 464
Query: 483 IAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILE-KGDINLSRLRDSQGLCPLH 541
IA G N + G P V N K++ + + D N + D + P+H
Sbjct: 465 IAAGCDNANVQNRVGRTPLHEVAEVGDQN----MLKIMFKLRADAN---IHDKEDKTPVH 517
Query: 542 IVAKMGGGSELIKLLVSYGAD--PDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
+ A+ G S + L+ +G DG + A GH +T L+ G +FM
Sbjct: 518 VAAERGDTSMVESLIDKFGGSIRARTRDGSTL---LHIAACSGHTSTALAFLKRGVPLFM 574
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAGN 629
+++ + A G V+ +L++ N
Sbjct: 575 PNKKGALGLHSAAAAGFNDVVKMLIARGTN 604
Score = 54.3 bits (129), Expect = 1e-06
Identities = 46/179 (25%), Positives = 86/179 (47%), Gaps = 10/179 (5%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
N Q+ GR PLH E+G N + ++ NI D KTP+ ++ + +
Sbjct: 473 NVQNRVGRTPLHEVAEVGDQNMLKIMFKLRADANIH--DKEDKTPVHVAAERGDTSMVES 530
Query: 482 LIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLH 541
LI + S+ T+ L++A + + A L++G + L + + +G LH
Sbjct: 531 LIDK----FGGSIRARTRDGSTLLHIAACSGHTSTALAFLKRG-VPLF-MPNKKGALGLH 584
Query: 542 IVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMK 600
A G ++++K+L++ G + D + + + + A+Q G A+ V+ LL GAD+ +K
Sbjct: 585 SAA-AAGFNDVVKMLIARGTNVD-VRTRDNYTALHVAVQSGKASVVETLLGSGADIHVK 641
>Hs20556512 [T] KOG0507 CASK-interacting adaptor protein (caskin) and related
proteins with ankyrin repeats and SAM domain
Length = 765
Score = 54.7 bits (130), Expect = 8e-07
Identities = 58/225 (25%), Positives = 102/225 (44%), Gaps = 28/225 (12%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N D G PLH+A G + V +L+ + + N+ D+ PL L+ ++ +
Sbjct: 146 VNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNV--ADSKGCYPLHLAAWKGDAQIVR 203
Query: 481 ILIAQG----NVNLSPSLCEGTKPQFHPLNVACSNKNY---------------EAAKVIL 521
+LI QG VN +L ++ P + + KN E KV+L
Sbjct: 204 LLIHQGPSHTRVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKVLL 263
Query: 522 EKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEID-GFNKWPPIFYAIQ 580
E ++ +R+++ PL + A + G E++K+L++ A P+ + K P+ A +
Sbjct: 264 E--ELTDPTMRNNKFETPLDLAA-LYGRLEVVKMLLN--AHPNLLSCNTKKHTPLHLAAR 318
Query: 581 EGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLS 625
GH VQVLL+ G D + + S + A G V+ +LL+
Sbjct: 319 NGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 362
>7291279 [R] KOG0502 Integral membrane ankyrin-repeat protein Kidins220
(protein kinase D substrate)
Length = 1498
Score = 54.7 bits (130), Expect = 8e-07
Identities = 55/216 (25%), Positives = 102/216 (46%), Gaps = 13/216 (6%)
Query: 432 LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG-NVNL 490
L +A G + V LL+ N+ D T LV + ++E+ L+ G NV+
Sbjct: 164 LLWAAGRGYKDIVELLVQRGAKVNVG--DKYGTTALVWACRRGNVEIVDTLLKAGANVDT 221
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
+ + PL VA + + + ILEK N++ L D G+ L +A G
Sbjct: 222 AGMY------SWTPLLVAAAGGHTDCVSSILEKKP-NVNAL-DKDGMTAL-CIASREGFQ 272
Query: 551 ELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFY 610
++ L++ GA + I P+ +A++ GH T V+ LL+ ADV ++ + + ++
Sbjct: 273 DIAASLIAAGAYIN-IQDRGADTPLIHAVKAGHRTVVEALLKKHADVDIQGKDRKTAIYT 331
Query: 611 ALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSLR 646
A+ +GH ++ +LL+ + + + D PL ++R
Sbjct: 332 AVEKGHTPIVKLLLATNPDLESATKDGDTPLLRAVR 367
>Hs18079216 [T] KOG0507 CASK-interacting adaptor protein (caskin) and related
proteins with ankyrin repeats and SAM domain
Length = 1431
Score = 54.3 bits (129), Expect = 1e-06
Identities = 47/184 (25%), Positives = 86/184 (46%), Gaps = 17/184 (9%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+N QD G LH+A G T +SLL+ + +D+ DN PL + E K
Sbjct: 42 VNFQDPDGFSALHHAALNGNTELISLLLEAQAA--VDIKDNKGMRPLHYAAWQGRKEPMK 99
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
+++ G+ PS EG PL++A + +Y+ ++++L+ + + D+ G PL
Sbjct: 100 LVLKAGSAVNIPS-DEG----HIPLHLAAQHGHYDVSEMLLQHQ--SNPCMVDNSGKTPL 152
Query: 541 HIVAKMGGGSELIKLLVSYG-------ADPDEIDGFNKWPPIFYAIQEGHATTVQVLLEL 593
+ + G +++LL+S P + N P+ A + GH +++LL+
Sbjct: 153 DLACEFGRVG-VVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQA 211
Query: 594 GADV 597
G D+
Sbjct: 212 GIDI 215
>At5g02620 [R] KOG0504 FOG: Ankyrin repeat
Length = 517
Score = 53.9 bits (128), Expect = 1e-06
Identities = 53/206 (25%), Positives = 94/206 (44%), Gaps = 14/206 (6%)
Query: 431 PLHYACELGKTNFVSLLIN----TELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG 486
PLH A GKT+ + +I EL + + + + +T L ++ + ++ KIL+
Sbjct: 13 PLHTAVREGKTDLLLEMIGEHDGVELKELLAEQNQSGETALYVAAEYGYTDMVKILMKH- 71
Query: 487 NVNLSPSLCEGTKPQ--FHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVA 544
S S+ GTK + F ++A N N + V++E LS DS LH A
Sbjct: 72 ----SDSVLAGTKAKNGFDAFHIAAKNGNLQVLDVLIEANP-ELSFTFDSSKTTALHTAA 126
Query: 545 KMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMK-DQQ 603
G G E++ L+ G D I N + A + GH V+ L+E A + + D++
Sbjct: 127 SQGHG-EIVCFLLDKGVDLAAIARSNGKTALHSAARNGHTVIVKKLIEKKAGMVTRVDKK 185
Query: 604 NLSQVFYALWEGHLSVLNVLLSYAGN 629
+ + A+ + +++VL+ G+
Sbjct: 186 GQTALHMAVKGQNTEIVDVLMEADGS 211
>SPAPB1E7.05_1 [R] KOG0504 FOG: Ankyrin repeat
Length = 724
Score = 53.5 bits (127), Expect = 2e-06
Identities = 55/216 (25%), Positives = 90/216 (41%), Gaps = 17/216 (7%)
Query: 418 RKLLNAQDIHGRMPLHYACELGKTNFVSLL--INTELIDNIDL-------LDNTSKTPLV 468
R LL ++ G+ +H +LG S I + + D+ L D TPL
Sbjct: 245 RILLVERNSKGQSVMHSVAKLGWAGLCSKFCEIVSSIPDSEPLNWMLPCWRDVMHDTPLT 304
Query: 469 LSIINNHIEVTKILIAQGNVNLSPSLCEGTKP-QFHPLNVACSNKNYEAAKVILEKGDIN 527
L+I NH+E L++ + + TKP PL + C +Y+ L N
Sbjct: 305 LAIKGNHVEALHALLSAQDKETT-----STKPGPVPPLVLTCCVGDYDLIVEELILAGFN 359
Query: 528 LSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTV 587
+ + D+ LH + E +K+L+ GA+P D N W P+ A G + V
Sbjct: 360 PNEV-DASSNTALHTAVRYNR-PECVKMLLKLGANPSARDFLNSWTPLMLASATGLSEIV 417
Query: 588 QVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVL 623
+L+ GA V D + + A+ G+L + + L
Sbjct: 418 SILVASGASVDEVDSSGWTAMEQAVVRGYLHLADKL 453
>Hs13376842 [M] KOG4177 Ankyrin
Length = 1166
Score = 53.1 bits (126), Expect = 2e-06
Identities = 58/228 (25%), Positives = 93/228 (40%), Gaps = 32/228 (14%)
Query: 421 LNAQDIHGRM--PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEV 478
+N +DI GR PLH+A + + V L+ ++ D PL + H EV
Sbjct: 517 VNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGA--DVHAKDKGGLVPLHNACSYGHYEV 574
Query: 479 TKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLC 538
++L+ G V L + F PL+ A + YE K++L+ G + RD G
Sbjct: 575 AELLVKHGAVVNVADLWK-----FTPLHEAAAKGKYEICKLLLQHGADPTKKNRD--GNT 627
Query: 539 PLHIV--------------------AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYA 578
PL +V AK G + + KL + + G + P+ A
Sbjct: 628 PLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHS-TPLHLA 686
Query: 579 IQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLSY 626
+ + LL+ GADV +D+ L + A GH+ V +L+ Y
Sbjct: 687 AGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY 734
Score = 53.1 bits (126), Expect = 2e-06
Identities = 52/206 (25%), Positives = 84/206 (40%), Gaps = 23/206 (11%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
+ A+D G +PLH AC G V+LL+ N DN + TPL + I I+V
Sbjct: 84 VQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNAR--DNWNYTPLHEAAIKGKIDVCI 141
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPL 540
+L+ G +P + + + + + G+ L +S
Sbjct: 142 VLLQHG-----------AEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLES------ 184
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMK 600
A+ G +++ LL + DG K P+ A VQ+LL+ GADV K
Sbjct: 185 ---ARSGNEEKMMALLTPLNVNCHASDG-RKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 240
Query: 601 DQQNLSQVFYALWEGHLSVLNVLLSY 626
D+ +L + A GH V +L+ +
Sbjct: 241 DKGDLVPLHNACSYGHYEVTELLVKH 266
>CE05814 [R] KOG0502 Integral membrane ankyrin-repeat protein Kidins220
(protein kinase D substrate)
Length = 1398
Score = 53.1 bits (126), Expect = 2e-06
Identities = 75/360 (20%), Positives = 148/360 (40%), Gaps = 38/360 (10%)
Query: 425 DIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIA 484
D+ G PL +A + V LL+N + ++ D T L+ + H+ V ++L+
Sbjct: 126 DLMGWSPLMWAVYKNHLDVVDLLVNAK----VNACDKFGSTALIWAARKGHLPVVQLLLN 181
Query: 485 QGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIV 543
G + + T L +A + +++L + ++N++ D GL L +
Sbjct: 182 SGAEVDAVGMYSSTA-----LMLATRGNFIQVVELLLTREPNVNVA---DQNGLTALGMA 233
Query: 544 AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQ 603
A+ G +++ + L++ GA ++ D F W + A++ G+A V+++L+ AD+ +D +
Sbjct: 234 AR-DGYADICESLINSGAFVNQCDRFGNWI-LTSAVRSGNAAIVRMILDKFADINCQDSE 291
Query: 604 NLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPLAGSLRPSDPGELFSDDQLSLND 663
+ + A+ + + +LL N + + + PL LR + + L
Sbjct: 292 KRTPLHLAIDKSFNDIAYILLEKKPNLELKNKDGETPL---LRAAKCRHVHLCTYL---- 344
Query: 664 SLKDIPDFTLPPPIIPLRKYGHNFLERKIFVKLSFKPGKESITLNKDDEMMLSSPGRITL 723
+ + + G N L + ++ + +++ N D +L P ++
Sbjct: 345 -------MSFGAKLAAVDNCGDNALH--LALRARSRRLTQALLSNPSDSRLLYRPNKLGQ 395
Query: 724 T------SSVSNIIPRNIILPIQEEDEKDIVFQIDSLDTFDIDIEIYPSFGTRLIAKTYA 777
T S+ I+P I PI ED+ D D DI PS L YA
Sbjct: 396 TPYSIDLSNPQPILPL-IFGPIDAEDKMDTAMGYDVYSNVLADIVCEPSLSLPLTIGLYA 454
>CE05333 [R] KOG0510 Ankyrin repeat protein
Length = 1188
Score = 53.1 bits (126), Expect = 2e-06
Identities = 62/236 (26%), Positives = 104/236 (43%), Gaps = 33/236 (13%)
Query: 430 MPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGNVN 489
+PLH A ++ + VS LI E DNID++D TPL++++ ++ + + LIA+ N
Sbjct: 329 VPLHVAAQMNQLEVVSYLIEEEK-DNIDVVDEQGLTPLMMAVTHDSKKCVEYLIAK-KAN 386
Query: 490 LSPSLCEGTKPQF--HPLNVACS---------NKNYEAAKVILEKGDINLSRLR------ 532
L+ + + P F N S KN E + L+ N R+
Sbjct: 387 LTITDKDERTPVFIGAKFNALSSVEYILDHLRKKNKETERSALKSPTRNTLRIVSEDVRR 446
Query: 533 ------DSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATT 586
D P+HIVA G E+++LL +GA +++ + A+ A
Sbjct: 447 TMVNMVDRDQNTPMHIVAS-NGYLEMMQLLQKHGASITQVNEDEET-----ALHRA-AIG 499
Query: 587 VQVLLELGADVF-MKDQQNLSQVFYALWEGHLSVLNVLLSYAGNRKRYSAFPDRPL 641
V+ LLE + MKD+ S + A GH + VLL +++ +++ PL
Sbjct: 500 VRQLLEWDIRLLLMKDEMGNSALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPL 555
>Hs22060186 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 632
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Query: 505 LNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPD 564
L+ A N + K + KG I + +L PLH + G S +++L+ YGADP
Sbjct: 94 LHWAAINNRIDLVKYYISKGAI-VDQLGGDLNSTPLHWATRQGHLSMVVQLM-KYGADPS 151
Query: 565 EIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGH 616
IDG I A Q GH + V L+ G DV M DQ ++ + +A + H
Sbjct: 152 LIDG-EGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTH 202
>At5g54710 [R] KOG0504 FOG: Ankyrin repeat
Length = 652
Score = 52.8 bits (125), Expect = 3e-06
Identities = 57/236 (24%), Positives = 104/236 (43%), Gaps = 46/236 (19%)
Query: 420 LLNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVT 479
L++ ++ G PLH A E+G N + ++ T + + ++ +T +L+ +NN++
Sbjct: 94 LVSVTNVDGNTPLHLAAEIGNINILWKMLETGEAECMK-INKQGQTAFILACLNNNVNSA 152
Query: 480 KILIAQGNVNLS-----------------------PSL-CEGTKPQFHPLNVACSNKNYE 515
+IL+ +G +++ P+L + + Q L+ AC + N E
Sbjct: 153 RILV-EGTSSMTMVELNAAFSEQQQVIIDSILEKFPNLILDADEEQSTLLHKACKSGNLE 211
Query: 516 AAKVILEKGDIN--LSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWP 573
A+ +L+ D+N ++ D GL PLH A + G E++K + K P
Sbjct: 212 MARTLLDV-DVNQEIAEKVDKDGLTPLH-RAVINGSVEILKEFLC------------KAP 257
Query: 574 PIFYAIQEGHATTVQVLL----ELGADVFMKDQQNLSQVFYALWEGHLSVLNVLLS 625
F +G TV L + A +FM N+ Q+ Y+L +VL+V S
Sbjct: 258 SSFNITTQGTIETVFHLAAKYQKTKAFIFMAQSANIRQLLYSLDAEDNTVLHVAAS 313
>7294632_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 959
Score = 52.8 bits (125), Expect = 3e-06
Identities = 59/250 (23%), Positives = 105/250 (41%), Gaps = 10/250 (4%)
Query: 387 EAALCPHQPRTFVLLAALYQYQNSIIQQEAFRKLLNAQDIHGRMPLHYACELGKTNFVSL 446
+ L Q T ++LAA+ + + + A L DI R L +A +G + V
Sbjct: 462 DVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSLGQLDITQRCALVHAARMGHLSVVKY 521
Query: 447 LINTELIDNIDLLDNTSKTPLVLSIINN----HIEVTKILIAQGNVNLSPSLCEGTKPQF 502
L+ + D T L ++I H ++ + L+ + G +P
Sbjct: 522 LLACDWSPRPHSQDVTRSVALQQALIGAAAQAHCKILEDLLDLNETEFDLDV-NGMEPSS 580
Query: 503 HPLNVACSNKN--YEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYG 560
L + + ++ + ++L +G +R R QG L + K G S +++ L+ G
Sbjct: 581 GELALTAAARHGCIDVVGILLSRGAQIDARNR--QGYSALWLAVKEGHWS-VVEHLLQRG 637
Query: 561 ADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVL 620
A DE G + P+ A +EGH V +LL GA +D + + + +A GHL+
Sbjct: 638 ALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAA 697
Query: 621 NVLLSYAGNR 630
L+ + NR
Sbjct: 698 KTLIEHGCNR 707
>Hs13899329 [R] KOG0504 FOG: Ankyrin repeat
Length = 854
Score = 52.4 bits (124), Expect = 4e-06
Identities = 44/189 (23%), Positives = 81/189 (42%), Gaps = 9/189 (4%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQGN 487
G +P+HYA G + LL+ + ++ TPL L+ H+EVT+ L+ +
Sbjct: 138 GALPIHYAAAKGDFPSLRLLVE-HYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECG 196
Query: 488 VNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMG 547
+ +G P L+ A + ++ D++LS +D G +H A G
Sbjct: 197 ADPHARAHDGMTP----LHAAAQMGHSPVIVWLVSCTDVSLSE-QDKDGATAMHFAASRG 251
Query: 548 GGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQ 607
L LL+ G ++ G P+ A + G Q+L+ GA++ ++D+ +
Sbjct: 252 HTKVLSWLLLHGGEISADLWGGT---PLHDAAENGELECCQILVVNGAELDVRDRDGYTA 308
Query: 608 VFYALWEGH 616
+ + GH
Sbjct: 309 ADLSDFNGH 317
>CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 850
Score = 52.0 bits (123), Expect = 5e-06
Identities = 50/191 (26%), Positives = 83/191 (43%), Gaps = 11/191 (5%)
Query: 413 QQEAFRKLLNAQ---DIHGRM---PLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTP 466
Q+ A R L++A ++ G + P+H A G T+ LL+ + D + L D+
Sbjct: 195 QENAVRTLISASANLNLGGAVNDRPIHLAAAKGLTSITKLLLEAKA-DPL-LADDEGNQA 252
Query: 467 LVLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDI 526
L + + + + +LI Q + +C L+++C + + K IL+
Sbjct: 253 LHYAAKSGSLVILNMLIKQVR-GTNDRICARNLYGDTALHLSCYSGRLDIVKSILDSSPT 311
Query: 527 NLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSY-GADPDEIDGFNKWPPIFYAIQEGHAT 585
N+ + + PLH G EL+ L+ Y G DP+ G + + A GH
Sbjct: 312 NIVNMENVFSETPLHAACTGGKSIELVSFLMKYPGVDPN-YQGQDGHTALHSACYHGHLR 370
Query: 586 TVQVLLELGAD 596
VQ LLE GAD
Sbjct: 371 IVQYLLENGAD 381
>At3g03790 [S] KOG1426 FOG: RCC1 domain
Length = 1073
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/87 (35%), Positives = 50/87 (56%), Gaps = 2/87 (2%)
Query: 515 EAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPP 574
++A IL+K N++ LR++ GL PLHI A +++ L++ GADPD DG + W
Sbjct: 31 DSALSILKKTGGNIN-LRNAYGLTPLHI-AVWRNHIPIVRRLLAAGADPDARDGESGWSS 88
Query: 575 IFYAIQEGHATTVQVLLELGADVFMKD 601
+ A+ GH VL++ GA ++D
Sbjct: 89 LHRALHFGHLAVASVLIDSGASFTLED 115
>7296936 [R] KOG0504 FOG: Ankyrin repeat
Length = 600
Score = 52.0 bits (123), Expect = 5e-06
Identities = 48/179 (26%), Positives = 87/179 (47%), Gaps = 18/179 (10%)
Query: 420 LLNAQDIH-GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEV 478
L+NA+ + G+ LH A E LL+ T + NI+ D+ +TPL+ +I + ++V
Sbjct: 205 LVNAKTLSDGKTALHMAIESKCAESARLLLQTNI--NINDTDDDGETPLMAAIACSMLDV 262
Query: 479 TKILIAQG-NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGL 537
+ L+ +G +N+ K L A ++ + AK++LE+G +R SQ L
Sbjct: 263 AEELVKRGARINIQ------DKQNHTALQYAVRGRHTQMAKLLLERG----ARRLASQHL 312
Query: 538 CPLHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGAD 596
L + + + EL++LL+ YG + + + PI AI G ++ LL + +
Sbjct: 313 LHLAVESNV---KELVELLLQYG-ESLSVWNLKNFTPIMLAIHRGRHEMLEYLLNVAEE 367
>7293339 [R] KOG0504 FOG: Ankyrin repeat
Length = 1409
Score = 52.0 bits (123), Expect = 5e-06
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 16/174 (9%)
Query: 428 GRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSK----TPLVLSIINNHIEVTKILI 483
G + LHYA G + V LL+ ++D+ NT TP+ L+ H+EV K L+
Sbjct: 16 GALALHYAAARGCLDCVQLLVAA----SVDICANTQMDNDVTPVYLAAQEGHLEVLKFLV 71
Query: 484 AQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIV 543
+ +L +G P + C + K +++ ++ LRD G PLH
Sbjct: 72 LEAGGSLYVRARDGMAPIHAASQMGC----LDCLKWMVQDQGVD-PNLRDGDGATPLHFA 126
Query: 544 AKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADV 597
A G S +++ L+++GA +D + K PI A + + VL++ G V
Sbjct: 127 ASRGHLS-VVRWLLNHGAKL-SLDKYGK-SPINDAAENQQVECLNVLVQHGTSV 177
>SPAC2F7.10 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 642
Score = 51.6 bits (122), Expect = 7e-06
Identities = 49/201 (24%), Positives = 88/201 (43%), Gaps = 17/201 (8%)
Query: 432 LHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG-NVNL 490
L A G+ + V LI++E ID ++ D T L + +N I + K L+ G +VN
Sbjct: 4 LFLAASQGELDTVKNLISSEKID-VNATDEGGATALHWAALNQQIPICKFLLEHGADVNA 62
Query: 491 SPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDINLSRLRDSQGLCPLHIVAKMGGGS 550
G Q P++ A + + +++ G L L+D QG LH+
Sbjct: 63 I-----GGDLQAAPIHWAAKRGSVKTVHYLVQHGADPL--LKDKQGFNCLHLAVHAASPL 115
Query: 551 ELIKLL---VSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQ 607
++ LL +S D+ + P+ +A G+ LL GADV D+ ++
Sbjct: 116 LVVYLLHLDISVDLRDDQ-----QHTPLMWASYHGNEPITNCLLRWGADVLATDEDKMTP 170
Query: 608 VFYALWEGHLSVLNVLLSYAG 628
+ +++ G+L + ++L G
Sbjct: 171 LHWSIVGGNLKCMKLILKEGG 191
>Hs7706377 [R] KOG0504 FOG: Ankyrin repeat
Length = 335
Score = 51.6 bits (122), Expect = 7e-06
Identities = 58/229 (25%), Positives = 102/229 (44%), Gaps = 37/229 (16%)
Query: 406 QYQNSIIQQEAFRKLLNAQDIH-----GRMPLHYACELGKTNFVSLLINTELIDNIDLLD 460
Q S++Q+E++R +N + + PL A G + V LI +DL+D
Sbjct: 51 QTLRSLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGSCVDFLIRKGA--EVDLVD 108
Query: 461 NTSKTPLVLSIINNHIEVTKILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVI 520
+T L ++++N H+E T+IL+ G + + S + P +H V + K +
Sbjct: 109 VKGQTALYVAVVNGHLESTQILLEAG-ADPNGSRHHRSTPVYHASRVG----RADILKAL 163
Query: 521 LEKG---DIN----------LSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADPD--- 564
+ G D+N SR S +CPL+I A + +LL+ GA+PD
Sbjct: 164 IRYGADVDVNHHLTPDVQPRFSRRLTSLVVCPLYISAAY-HNLQCFRLLLLAGANPDFNC 222
Query: 565 ----EIDGFNKWPP---IFYAIQEG-HATTVQVLLELGADVFMKDQQNL 605
GF + P + ++ G A V +L+E GA++ + ++L
Sbjct: 223 NGPVNTQGFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESL 271
>At2g26650 [PT] KOG0498 K+-channel ERG and related proteins contain PAS/PAC
sensor domain
Length = 857
Score = 51.6 bits (122), Expect = 7e-06
Identities = 48/163 (29%), Positives = 71/163 (43%), Gaps = 15/163 (9%)
Query: 422 NAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKI 481
N D +GR PLH A G N V LL+ N D PL +++ H +V K+
Sbjct: 545 NESDNNGRTPLHIAASKGTLNCVLLLLEYHADPN--CRDAEGSVPLWEAMVEGHEKVVKV 602
Query: 482 LIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAK-VILEKGDINLSRLRDSQGLCPL 540
L+ G+ ++ G F A N + K ++L GD+ R + G L
Sbjct: 603 LLEHGS-----TIDAGDVGHF--ACTAAEQGNLKLLKEIVLHGGDVTRPR---ATGTSAL 652
Query: 541 HIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGH 583
H A E++K L+ GAD ++ D + W P A Q+GH
Sbjct: 653 H-TAVCEENIEMVKYLLEQGADVNKQD-MHGWTPRDLAEQQGH 693
>Hs4506217 [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 226
Score = 51.2 bits (121), Expect = 9e-06
Identities = 40/138 (28%), Positives = 67/138 (47%), Gaps = 6/138 (4%)
Query: 505 LNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLHIVAKMGGGSELIKLLVSYGADP 563
L+ ACS + E + +L+ G +N +D G PLHI A G E++K L+ GA
Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVND---KDDAGWSPLHIAAS-AGRDEIVKALLGKGAQV 99
Query: 564 DEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKDQQNLSQVFYALWEGHLSVLNVL 623
+ ++ N P+ YA + +LLE GA+ KD + + A +G+L ++++L
Sbjct: 100 NAVNQ-NGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 624 LSYAGNRKRYSAFPDRPL 641
L Y + + PL
Sbjct: 159 LYYKASTNIQDTEGNTPL 176
>Hs13375989 [R] KOG0504 FOG: Ankyrin repeat
Length = 278
Score = 51.2 bits (121), Expect = 9e-06
Identities = 68/278 (24%), Positives = 116/278 (41%), Gaps = 43/278 (15%)
Query: 429 RMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTKILIAQG-- 486
R P+H A + G++ + LI + N +D S TPL + + ++L+A G
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVNQVTVD--SITPLHAASLQGQARCVQLLLAAGAQ 77
Query: 487 ----NVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKG-DINLSRLRDSQGLCPLH 541
N++ S LC+ AC++ + E K+ L G +N S PLH
Sbjct: 78 VDARNIDGSTPLCD-----------ACASGSIECVKLSLSYGAKVNPPLYTAS----PLH 122
Query: 542 IVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFMKD 601
A M G SE ++LL+ GA+ + D + P+ A H V+VLL GA+V
Sbjct: 123 -EACMSGSSECVRLLIDVGANLEAHD-CHFGTPLHVACAREHLDCVKVLLNAGANV-NAA 179
Query: 602 QQNLSQVFYALWEGHLSVLNVLLSYAGN---RKRYSAFPDRPLAGSLRPSDPGELFSDDQ 658
+ + + + +A ++ ++ +L+ + GN R P S P+ E +
Sbjct: 180 KLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTP 239
Query: 659 LSLND-------------SLKDIPDFTLPPPIIPLRKY 683
L+L+ L+ I +PP +I Y
Sbjct: 240 LTLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSY 277
>7294199_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 708
Score = 51.2 bits (121), Expect = 9e-06
Identities = 54/209 (25%), Positives = 89/209 (41%), Gaps = 9/209 (4%)
Query: 421 LNAQDIHGRMPLHYACELGKTNFVSLLINTELIDNIDLLDNTSKTPLVLSIINNHIEVTK 480
LNA++ + LH A G N V L+ L + L D+ TPL +I H E+
Sbjct: 124 LNARNKRRQTSLHIAVNKGHLNVVKTLLT--LGCHPSLQDSEGDTPLHDAISKEHDEMLS 181
Query: 481 ILIAQGNVNLSPSLCEGTKPQFHPLNVACSNKNYEAAKVILEKGDIN-LSRLRDSQGLCP 539
+L+ G + F+ L+ A N A K++L K + + + G
Sbjct: 182 LLLDFG-----ADITLNNNNGFNALHHAALKGNPSAMKILLTKTNRPWIVEEKKDDGYTA 236
Query: 540 LHIVAKMGGGSELIKLLVSYGADPDEIDGFNKWPPIFYAIQEGHATTVQVLLELGADVFM 599
LH+ A + E+ +LLV G + N + A++ H V++L++ GAD+ +
Sbjct: 237 LHLAA-LNNHVEIAELLVHMGKANMDRQNVNLQTALHLAVERQHVQIVKLLVQDGADLNI 295
Query: 600 KDQQNLSQVFYALWEGHLSVLNVLLSYAG 628
D+ + + AL LS L L G
Sbjct: 296 PDKDGDTPLHEALRHHTLSQLKQLQDVEG 324
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,830,401
Number of Sequences: 60738
Number of extensions: 2804462
Number of successful extensions: 9548
Number of sequences better than 1.0e-05: 92
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 8601
Number of HSP's gapped (non-prelim): 471
length of query: 1148
length of database: 30,389,216
effective HSP length: 117
effective length of query: 1031
effective length of database: 23,282,870
effective search space: 24004638970
effective search space used: 24004638970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)