ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4115 good S KOG2111 Function unknown Uncharacterized conserved protein, contains WD40 repeats
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4115 1419922 1420938 339
(339 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR223c [S] KOG2111 Uncharacterized conserved protein contains W... 193 3e-49
7299116 [S] KOG2111 Uncharacterized conserved protein contains W... 123 3e-28
At2g40810 [S] KOG2111 Uncharacterized conserved protein contains... 107 3e-23
Hs9625016 [S] KOG2111 Uncharacterized conserved protein contains... 106 6e-23
Hs5901988 [S] KOG2111 Uncharacterized conserved protein contains... 105 7e-23
SPAC458.06 [S] KOG2111 Uncharacterized conserved protein contain... 105 9e-23
At3g62770 [S] KOG2111 Uncharacterized conserved protein contains... 99 1e-20
At3g56440 [S] KOG2111 Uncharacterized conserved protein contains... 92 1e-18
At5g05150 [S] KOG2111 Uncharacterized conserved protein contains... 90 4e-18
SPAC823.16c [S] KOG2110 Uncharacterized conserved protein contai... 89 7e-18
Hs8922208 [S] KOG2110 Uncharacterized conserved protein contains... 71 2e-12
Hs13626265 [S] KOG2111 Uncharacterized conserved protein contain... 71 3e-12
CE10268 [S] KOG2110 Uncharacterized conserved protein contains W... 69 1e-11
7298770 [S] KOG2110 Uncharacterized conserved protein contains W... 69 1e-11
CE28977 [S] KOG2111 Uncharacterized conserved protein contains W... 67 3e-11
7295146 [S] KOG2110 Uncharacterized conserved protein contains W... 65 2e-10
Hs22064307 [S] KOG2111 Uncharacterized conserved protein contain... 63 5e-10
Hs7706294 [S] KOG2110 Uncharacterized conserved protein contains... 63 7e-10
Hs7661580 [S] KOG2110 Uncharacterized conserved protein contains... 61 3e-09
YFR021w [S] KOG2110 Uncharacterized conserved protein contains W... 60 5e-09
SPAC589.07c [S] KOG2110 Uncharacterized conserved protein contai... 59 8e-09
>YGR223c [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 448
Score = 193 bits (490), Expect = 3e-49
Identities = 140/403 (34%), Positives = 193/403 (47%), Gaps = 87/403 (21%)
Query: 1 MLTRNPI--VPENHVSNPIVDYEFNQDQSCLIVSTPKSFDIYNVHPLKRIMSQEMPDAGT 58
M R PI N + FNQD SC V+ F I+N PL +S+ ++ T
Sbjct: 1 MDVRRPIREAVNNRRKPKFLSVSFNQDDSCFSVALENGFRIFNTDPLTSKLSKTFKESAT 60
Query: 59 ----------IRMLHRTNYIAFVSTKKELLH------IWDDVKKQDITRVKLDAAVKDLF 102
RML+RTNYIA V K H IWDD+ +++ +K +++KD+F
Sbjct: 61 NQSRGTGIGYTRMLYRTNYIALVGGGKRPRHALNKLIIWDDLLQKETITLKFMSSIKDVF 120
Query: 103 LSREFIVVSQGDVISIFKFGNPWNKITE--DIKFGG-----VCEFAN------------- 142
LSR IVV + I IF+F +I DI G VC +
Sbjct: 121 LSRIHIVVVLENTIEIFQFQTNPQRICPILDIPPNGSVDYVVCSSKHLQSQASQSQSKIL 180
Query: 143 GLLVYSNEFNLGQIHVTRL-------QTDAEQVVGKGVLVKAHANPVKMVRLNRKGDMVA 195
++ + + +GQI V L Q E + ++KAH NP+K+VRLNR+G MVA
Sbjct: 181 EIIAFPSNKCVGQIQVADLSQIKYNSQNPKESALLPTSIIKAHKNPIKLVRLNRQGTMVA 240
Query: 196 TCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAVVSDKWTLHVFEVF- 254
TCS GTLIR+F T NG L++EFRRG+D+ I +M +SP+GSKLAV+S+K TLH+F++F
Sbjct: 241 TCSVQGTLIRIFSTHNGTLIKEFRRGVDKADIYEMSFSPNGSKLAVLSNKQTLHIFQIFE 300
Query: 255 -----------NDAENKRHVLKDWI-----NIKYFQSEWSICNFKLK---VSKGSND--- 292
+ A H LK++I KY S WSICN LK ND
Sbjct: 301 TTNTETNTPDHSRANGSSHPLKNYIPKGLWRPKYLDSVWSICNAHLKNPIFDAHRNDNSG 360
Query: 293 ------------CKIAWISDT-------GLVIVWPNRRLADTF 316
C+I W D+ LV+VW N + + F
Sbjct: 361 DVTHDNEFYKDRCRIGWCQDSNNREQDDSLVLVWQNSGIWEKF 403
>7299116 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 340
Score = 123 bits (309), Expect = 3e-28
Identities = 89/292 (30%), Positives = 133/292 (45%), Gaps = 21/292 (7%)
Query: 7 IVPENHVSNPIVDYEFNQDQSCLIVSTPKSFDIYNVHPLKRIMSQEMPDAGT--IRMLHR 64
+ +N N ++ FNQDQ C +T F +YN PLK Q P+ G + ML R
Sbjct: 3 LTEQNPYGNGLLYAAFNQDQGCFACATDTGFRVYNCDPLKEKERQYFPEGGLSHVEMLFR 62
Query: 65 TNYIAFVSTKKELLH------IWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISI 118
NY+A V L+ +WDD+KK + + V+ + L R+ IVV VI +
Sbjct: 63 CNYLALVGGGIRPLYPPNKVIVWDDLKKSPAISLDFNQPVRAVRLRRDRIVVVLEGVIKV 122
Query: 119 FKFGNPWNKITEDIKFGGVCEFANGLLVYSNEFNLGQIHVTRLQTDAEQVVGKG------ 172
F F + + + NGL V N + +T Q+V
Sbjct: 123 FTF----TQQPQQLHVFETSSNPNGLCVLCPHSNKSLLAFPGRRTGHVQIVDLANTERAP 178
Query: 173 VLVKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRW 232
+ V AH + + LN +G +AT + GTLIR+F T++G V E RRG + +I + +
Sbjct: 179 LEVIAHEAGISCIALNLQGTRLATAGEKGTLIRIFDTESGKKVSELRRGSNHANIFCINF 238
Query: 233 SPDGSKLAVVSDKWTLHVFEVFNDAENKRHVLKDWINIKYFQSEWSICNFKL 284
+ + + V SD T+H VFN +NK I KYF S+WS F +
Sbjct: 239 NHQSTMVVVASDHGTIH---VFNLEDNKPRESSLPIIPKYFSSQWSFVKFSI 287
>At2g40810 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 369
Score = 107 bits (266), Expect = 3e-23
Identities = 76/250 (30%), Positives = 120/250 (47%), Gaps = 19/250 (7%)
Query: 17 IVDYEFNQDQSCLIVSTPKSFDIYNVHPLKRIMSQEMPDAG--TIRMLHRTNYIAFVSTK 74
+V +NQD SC T F IYN P K +E+ D G + ML R+N +A V
Sbjct: 8 LVSVCWNQDSSCFAAGTSHGFRIYNCEPFKETFRRELKDGGFKIVEMLFRSNILALVGGG 67
Query: 75 KELLH------IWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGNP--WN 126
+ IWDD + + I+ + ++ + L R+ IVV I ++ F + +
Sbjct: 68 PNSQYPSSKVLIWDDHQSRCISEFAFRSEIRAVKLRRDRIVVVLEHKIYVYNFMDLRLLH 127
Query: 127 KITEDIKFGGVC---EFANGLLVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVKAHANPVK 183
+I G+C +N ++ N G+I V + Q++ AH + +
Sbjct: 128 QIETQANPRGLCCLSHHSNTSVLACPGLNRGEIRVEHFGLNMVQIIN------AHDSSIA 181
Query: 184 MVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAVVS 243
+ L G ++AT S GTLIR+F T +G ++E RRG+DR I + SP+ LAV S
Sbjct: 182 CMTLTLDGLLLATASTKGTLIRIFNTMDGTRLQEVRRGVDRADIYSIALSPNVQWLAVSS 241
Query: 244 DKWTLHVFEV 253
DK T+H+F +
Sbjct: 242 DKGTVHIFSL 251
>Hs9625016 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 286
Score = 106 bits (264), Expect = 6e-23
Identities = 81/259 (31%), Positives = 127/259 (48%), Gaps = 22/259 (8%)
Query: 61 MLHRTNYIAFVSTKKELLH------IWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGD 114
ML R NY+A V K+ + IWDD+KK+ + ++ VK + L R+ IVV
Sbjct: 1 MLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDS 60
Query: 115 VISIFKFG-NPWNKITEDIKFG--GVCEFA----NGLLVYSNEFNLGQIHVTRLQTDAEQ 167
+I +F F NP + + G+C N LL + + G + + L + +
Sbjct: 61 MIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGT-HTGHVQLVDLASTEKP 119
Query: 168 VVGKGVLVKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSI 227
V + AH + + LN +G +AT S+ GTLIR+F T +G L++E RRG +I
Sbjct: 120 PVD----IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANI 175
Query: 228 IDMRWSPDGSKLAVVSDKWTLHVFEVFNDAENKRHVLKDWINI-KYFQSEWSICNFKLKV 286
+ ++ D S + V SD T+H+F + NK+ L + KYF S+WS F +V
Sbjct: 176 YCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKF--QV 233
Query: 287 SKGSNDCKIAWISDTGLVI 305
GS C A+ ++ VI
Sbjct: 234 PSGS-PCICAFGTEPNAVI 251
>Hs5901988 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 360
Score = 105 bits (263), Expect = 7e-23
Identities = 82/293 (27%), Positives = 135/293 (45%), Gaps = 28/293 (9%)
Query: 17 IVDYEFNQDQSCLIVSTPKSFDIYNVHPLKR---IMSQEMPDAGTIRMLHRTNYIAFVST 73
+ FNQDQSC + IYNV PL + +++ G + MLHR+N +A V
Sbjct: 9 VTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGG 68
Query: 74 KKE------LLHIWDDVKKQDITRVKL------DAAVKDLFLSREFIVVSQGDVISIFKF 121
+ IWDD ++ ++ KL V + + + IV+ + I ++ F
Sbjct: 69 GSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSF 128
Query: 122 GNPWNKITE-DIKFG--GVCEFANGL----LVYSNEFNLGQIHVTRLQTDAEQVVGKGVL 174
+ K+ E D + G+C+ L LV+ G + + L +
Sbjct: 129 PDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGH-KCGSLQLVDLASTKPGTSSAPFT 187
Query: 175 VKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSP 234
+ AH + + V LN+ G +VA+ SQ GTLIR+F T + + E RRG D ++ + +S
Sbjct: 188 INAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSH 247
Query: 235 DGSKLAVVSDKWTLHVFEVFNDAENKRHVLKDWINI-----KYFQSEWSICNF 282
D S L SDK T+H+F + + N+R L + +Y S+WS+ +F
Sbjct: 248 DSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASF 300
>SPAC458.06 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 364
Score = 105 bits (262), Expect = 9e-23
Identities = 65/258 (25%), Positives = 127/258 (49%), Gaps = 19/258 (7%)
Query: 23 NQDQSCLIVSTPKSFDIYNVHPLKRIMSQEMPDAGT--IRMLHRTNYIAFVST------K 74
NQD SC+ V+ + I+ ++PLK ++ D G ++ML R+N + V
Sbjct: 10 NQDASCMSVALDTGYKIFQINPLKLRAQRQFNDGGLSIVKMLFRSNVLLLVGGGGNPKYA 69
Query: 75 KELLHIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGN--PWNKITEDI 132
L +WDDVK++ + ++L+ +K + + + ++ + +++FGN + +
Sbjct: 70 PNKLIVWDDVKERPVKELELNFEIKGICFDGKLLAIATASKLFLYQFGNNLKLQRCLDTQ 129
Query: 133 KFGGVCEFANGL----LVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVKAHANPVKMVRLN 188
G+C + +V+ + +GQ+ + L D +V AH + + + ++
Sbjct: 130 NPKGLCAMVTTVEKTAIVFPSR-KVGQLQILFLFKDHMNTS----IVPAHDSEISCLGIS 184
Query: 189 RKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAVVSDKWTL 248
+ G +A+ S +GTLIR++ ++ G + EFRRG T++ + +SPD LA S K TL
Sbjct: 185 KTGSKIASSSTNGTLIRIWNSETGEKICEFRRGYQHTAVCQLAFSPDELLLACASKKETL 244
Query: 249 HVFEVFNDAENKRHVLKD 266
H+F + R + +
Sbjct: 245 HIFSLHGSPNTIRQLTSE 262
>At3g62770 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 432
Score = 98.6 bits (244), Expect = 1e-20
Identities = 85/324 (26%), Positives = 138/324 (42%), Gaps = 53/324 (16%)
Query: 5 NPIVPENHVSNP--IVDYEFNQDQSCLIVSTPKSFDIYNVHPLKRIMSQEMPDAG---TI 59
+P P V P ++ FNQD +C V T + F I N P + I ++ G +
Sbjct: 64 SPPTPNLPVMPPPSVLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVV 123
Query: 60 RMLHRTNYIAFVSTKKELLH------IWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQG 113
ML R N +A V + + IWDD + + I + + V+ + L R+ I+V
Sbjct: 124 EMLFRCNILALVGGGPDPQYPPNKVMIWDDHQGRCIGELSFRSDVRSVRLRRDRIIVVLE 183
Query: 114 DVISIFKFGNP--WNKITEDIKFGGVCEFANG---LLVYSNEFNLGQIHVTRLQTDAEQV 168
I ++ F + ++I G+C + G +++ GQ+ + + +
Sbjct: 184 QKIFVYNFSDLKLMHQIETIANPKGLCAVSQGVGSMVLVCPGLQKGQVRIEHYASKRTK- 242
Query: 169 VGKGVLVKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREF--------RR 220
V AH + + L + G ++AT S GTL+R+F T +G L +E +
Sbjct: 243 -----FVMAHDSRIACFALTQDGHLLATASSKGTLVRIFNTVDGTLRQESGTSEDEIGKE 297
Query: 221 GLDRTSIIDMRWSPDGSKLAVVSDKWTLHVFEVFNDAENKRHVLKDWINI---------- 270
G DR I + +S + LAV SDK T+HVF + N +KD I
Sbjct: 298 GADRAEIYSLAFSSNAQWLAVSSDKGTVHVFGL---KVNSGSQVKDSSRIAPDATPSSPS 354
Query: 271 ----------KYFQSEWSICNFKL 284
+YF SEWS+ F+L
Sbjct: 355 SSLSLFKVLPRYFSSEWSVAQFRL 378
>At3g56440 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 400
Score = 91.7 bits (226), Expect = 1e-18
Identities = 76/271 (28%), Positives = 121/271 (44%), Gaps = 41/271 (15%)
Query: 17 IVDYEFNQDQSCLIVSTPKSFDIYNVHPLKRIMSQEMPDAG--TIRMLHRTNYIAFV--- 71
+V +NQD SC T F IYN P K +E+ D G + ML R+N +A V
Sbjct: 36 LVSVSWNQDYSCFAAGTSHGFRIYNCEPFKETFRRELKDGGFKIVEMLFRSNILALVGGG 95
Query: 72 ---STKKELLHIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGNPWNKI 128
+ IWDD + + I+ + ++ + L R+ IVV I ++ F + ++
Sbjct: 96 PNSQYPSNKVLIWDDHQGRCISEFTFRSEIRAVKLRRDRIVVVLEHKIYVYNFMD--LRL 153
Query: 129 TEDIKFGGVCEFAN--GLLVYSNEFNLGQIHVTRLQTDAEQVVGKGV----LVKAHANPV 182
I+ AN GL S+ N + ++ +V G+ ++ AH + +
Sbjct: 154 LHQIE-----NMANPRGLCCLSHHMNTSVLACPGIRRGEVRVEHFGLNMVQIINAHDSNI 208
Query: 183 KMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVRE--------------------FRRGL 222
+ L G ++AT S GTLIR+F T +G ++E RRG+
Sbjct: 209 ACMTLTLDGLLLATASTKGTLIRIFNTMDGTRLQEDSVKVMVEQTSCHDLFRKTLVRRGV 268
Query: 223 DRTSIIDMRWSPDGSKLAVVSDKWTLHVFEV 253
DR I + SP+ LAV SDK T+H+F +
Sbjct: 269 DRADIYSIALSPNVQWLAVSSDKGTVHIFSL 299
>At5g05150 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 374
Score = 90.1 bits (222), Expect = 4e-18
Identities = 71/255 (27%), Positives = 127/255 (48%), Gaps = 21/255 (8%)
Query: 17 IVDYEFNQDQSCLIVSTPKSFDIYNVHPL-KRIMSQEMPDAG--TIRMLHRTNYIAFVST 73
++ +NQ S IV T F++Y+ P+ K+ +S+ ++G ML +N AFV
Sbjct: 33 VLSVAWNQVCSGFIVGTNHGFNVYSCKPMIKKSISRAPHESGFKVAEMLFLSNLFAFVGN 92
Query: 74 -------KKELLHIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGN-PW 125
+ +WDD + ++ + + V + L+RE +VV I ++ F N
Sbjct: 93 GYNNSEYPPNKVFVWDDYRNCCLSELTFKSEVIAVKLAREHVVVVLKQNIYVYTFNNLKV 152
Query: 126 NKITEDIKFG-GVC---EFANGLLVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVKAHANP 181
+++ E + G+C + ++ F+ GQ+ V L+ + + +KAH +
Sbjct: 153 DRVIETLMNPKGLCCVTHVESKAVLACPGFHPGQVQVHDLRWNVIK------FIKAHDSA 206
Query: 182 VKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAV 241
+ + L G ++AT S GTLIR+F +G L++EFRRG++R I ++ S + +A
Sbjct: 207 IACMTLTLDGSLLATASTKGTLIRIFNAVDGTLLQEFRRGVERAEIYNVAISSNLKWVAA 266
Query: 242 VSDKWTLHVFEVFND 256
S+K TLHVF + D
Sbjct: 267 SSEKGTLHVFRLRPD 281
>SPAC823.16c [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 335
Score = 89.4 bits (220), Expect = 7e-18
Identities = 65/237 (27%), Positives = 113/237 (47%), Gaps = 10/237 (4%)
Query: 22 FNQDQSCLIVSTPKSFDIYNVHPLKRIMSQEMPDAGTIRMLHRTNYIAFVSTKKE---LL 78
+NQD+ L + + + +Y +P S++ A ML+ ++ +AFV+ E LL
Sbjct: 10 WNQDRGFLSIGSENGYQVYRSNPFTLCFSKKANGASICEMLYESSLLAFVNISPESTRLL 69
Query: 79 HIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGNPWNKITEDIKFGGVC 138
+ D + + R+ + V + + +VV I ++ N T + G V
Sbjct: 70 KLVDIKRDIVLCRIFYPSPVLSVRFTWNRLVVLIKGSIYVYNLKNMELINTLNTSKGNVI 129
Query: 139 EFA--NGLLVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVKAHANPVKMVRLNRKGDMVAT 196
FA + Y++ N G I++ L T L+ H++ V++V + +G ++AT
Sbjct: 130 AFAVHENYVAYNSPTNPGDIYLASLDTAIPVT-----LIHCHSSAVQVVDFHPRGHLIAT 184
Query: 197 CSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAVVSDKWTLHVFEV 253
S GT+IRV T +G LV E RRG SI+ + + P LA S+ T+HVF++
Sbjct: 185 ASAKGTVIRVITTSDGELVTELRRGYIPASIVSISFHPVEPFLACASENGTIHVFKI 241
>Hs8922208 [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 441
Score = 71.2 bits (173), Expect = 2e-12
Identities = 62/258 (24%), Positives = 119/258 (46%), Gaps = 18/258 (6%)
Query: 9 PENHVSNPIVDYEFNQDQSCLIVSTPKSFDIYNVHPLKRIM----SQEMPDAGTIRMLHR 64
P V + + + FNQD + L T + ++++ ++++ S E+PD + L
Sbjct: 4 PPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFS 63
Query: 65 TNYIAFVS-TKKELLHIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGN 123
++ + VS TK ++++ K +I + + + L+R+ ++V + I I +
Sbjct: 64 SSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKD 123
Query: 124 -PWNKITEDIKFG--GVCEFA----NGLLVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVK 176
K DI G+C + N L Y G+I + ++ + V +
Sbjct: 124 MKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVL--YDGNSLKTV---CTIA 178
Query: 177 AHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDR-TSIIDMRWSPD 235
AH + + N G +A+ S+ GT+IRVF +G + EFRRG+ R +I + +S D
Sbjct: 179 AHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMD 238
Query: 236 GSKLAVVSDKWTLHVFEV 253
L S+ T+H+F++
Sbjct: 239 SQFLCASSNTETVHIFKL 256
>Hs13626265 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 230
Score = 70.9 bits (172), Expect = 3e-12
Identities = 60/226 (26%), Positives = 99/226 (43%), Gaps = 20/226 (8%)
Query: 61 MLHRTNYIAFVSTKKE------LLHIWDDVKKQDITRVKL------DAAVKDLFLSREFI 108
MLHR N +A V + IWDD ++ ++ +L V L + I
Sbjct: 1 MLHRCNLLALVGGGSSPKFSEISVLIWDDAREGKDSKERLVLEFIFTKPVLSLCMLHGKI 60
Query: 109 VVSQGDVISIFKFGNPWNKITE---DIKFGGVCEFANGL----LVYSNEFNLGQIHVTRL 161
V + I ++ F + K+ E + +C+ L LV+ G + + L
Sbjct: 61 VTVLKNRIYVYSFPDNPRKLFEFDTRVNPNRLCDLCPSLDKQLLVFPGH-KCGSLQLVDL 119
Query: 162 QTDAEQVVGKGVLVKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRG 221
+ + + AH + + V LN+ G +VA+ SQ+GTLIR+F T + E RG
Sbjct: 120 ASTKPGTMSAPFTINAHQSDITCVSLNQPGTVVASASQNGTLIRLFDTQFKEKLVELHRG 179
Query: 222 LDRTSIIDMRWSPDGSKLAVVSDKWTLHVFEVFNDAENKRHVLKDW 267
D ++ + +S D S L SDK T+H+F + + N+ L W
Sbjct: 180 TDPATLYCINFSHDSSFLCASSDKGTIHIFALKDTHLNRCSALAPW 225
>CE10268 [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 412
Score = 68.6 bits (166), Expect = 1e-11
Identities = 64/258 (24%), Positives = 111/258 (42%), Gaps = 38/258 (14%)
Query: 22 FNQDQSCLIVSTPKSFDIYNVHPL----------KRIMSQEMPDAGTIRMLHRTNYIAFV 71
FNQD + V + Y + + + + + I L + + +
Sbjct: 18 FNQDSKVICVGHKDGYMFYKTADILENNTLTYEGENLTHLGLNNCLIIERLFSSALMVVI 77
Query: 72 STKK-ELLHIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGN------- 123
S K +LH++ + I + + +V + L+R+ IVV D I I+ +
Sbjct: 78 SQKDPRVLHVYHFTSRNIICDHRFNKSVLTVRLNRDRIVVCLEDCIYIYNLKDMKMMHNI 137
Query: 124 ---PWNKITEDIKFGGVCEFA----NGLLVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVK 176
P NK+ GV + N L+ Y + G +H+ DA +
Sbjct: 138 MDTPTNKL-------GVLDLTSNPGNALIAYPGSTDTGSVHLF----DAINLSSVSTF-N 185
Query: 177 AHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDR-TSIIDMRWSPD 235
AH + ++ N++G+M+AT S GT+IRV+ NG + EFRRG+ R +I + +S D
Sbjct: 186 AHEGTIACLKFNQEGNMIATASTKGTVIRVYSVPNGHRLFEFRRGVTRCVNIYSLCFSSD 245
Query: 236 GSKLAVVSDKWTLHVFEV 253
L S+ T+HVF++
Sbjct: 246 SKYLTSSSNTETVHVFKL 263
>7298770 [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 466
Score = 68.6 bits (166), Expect = 1e-11
Identities = 63/246 (25%), Positives = 117/246 (46%), Gaps = 24/246 (9%)
Query: 22 FNQDQSCLIVSTP---KSFDIYNVHPLKRIMSQEMPDAGTI--RMLHRTNYIAFVSTKKE 76
FNQD + L V +P + F I + ++ I +++ + I R+ + + + + K
Sbjct: 3 FNQDFTSLSVLSPTGLRLFSISSQDKVEEIFAKDNTEQIRIVERLFNSSLVVLVTAQKPN 62
Query: 77 LLHIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGNPWNKITEDIKF-- 134
L + KKQDI + + + ++R+ ++V + I I + KI I+
Sbjct: 63 CLKMLHFKKKQDICNCFYPSEILCVRMNRQRLIVCLAESIHIHDIRDM--KILHSIENIA 120
Query: 135 ---GGVCEFA-NGLLVYSNEFNLGQIHV---TRLQTDAEQVVGKGVLVKAHANPVKMVRL 187
G+C + N L + G++ + ++L+T G+ ++AH + +
Sbjct: 121 PNEQGLCALSLNSHLAFPVCQTSGELRIFNASKLRT--------GMTIRAHDTSLSALAF 172
Query: 188 NRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAVVSDKWT 247
+ G ++AT S+ GT+IRVF NG V+EFRRG+ I + +S G L S+ T
Sbjct: 173 SPSGALLATASERGTVIRVFCVKNGQRVQEFRRGVSCVRIASLVFSASGDFLCASSNTET 232
Query: 248 LHVFEV 253
+HVF++
Sbjct: 233 VHVFKI 238
>CE28977 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 440
Score = 67.4 bits (163), Expect = 3e-11
Identities = 43/117 (36%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 151 FNLGQIHVTRLQTDAEQVVGKGVLVKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTD 210
F G + + L + ++++AH + V LN +G +VAT S GT+IRVF
Sbjct: 245 FKTGSVQIMHLNALTARESKSPIVIEAHLTDIAQVALNCQGTLVATGSTKGTVIRVFDAR 304
Query: 211 NGVLVREFRRGLDRTSIIDMRWSPDGSKLAVVSDKWTLHVFEVFNDAE--NKRHVLK 265
+ E RRG + + M +SP S LAV SDK TLH+F + DAE K++VL+
Sbjct: 305 TKGPLYELRRGTVQAHLQCMAFSPCSSYLAVASDKGTLHMFGI-RDAEPQKKKNVLE 360
>7295146 [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 442
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/251 (24%), Positives = 113/251 (44%), Gaps = 22/251 (8%)
Query: 22 FNQDQSCLIVSTPKSFDIYNV----HPLKRIMSQEMPDAGTIRMLHRTNYIAFVSTKK-E 76
FNQ+ + L V+T + +Y++ L +I + + I L ++ +A VS +
Sbjct: 19 FNQNITSLAVATSGGYSLYSLGSVDSTLDKIYHTKSDELFLIERLFESSLVAIVSQRAPR 78
Query: 77 LLHIWDDVKKQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGNPWNKITEDIKFG- 135
L + K+ +I + + L+RE ++V + + I + K+ I+
Sbjct: 79 KLKVCHFKKQSEICNYSYANTILAVKLNRERLIVCLEESLYIHNIQDM--KVVHTIRDTP 136
Query: 136 ----GVCEFANG----LLVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVKAHANPVKMVRL 187
G+C ++ L Y G++ + DA + K ++ AH P+ +
Sbjct: 137 CNPQGLCALSSSSEHCYLAYPGSVTAGEVQIF----DAINLHAK-TMIPAHDTPLAALAF 191
Query: 188 NRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDR-TSIIDMRWSPDGSKLAVVSDKW 246
+ G +AT S+ GT+IRVF + +G + E RRGL R SI+ + +S L S+
Sbjct: 192 SPSGTEIATASERGTVIRVFSSQDGSRLFELRRGLKRCVSIVSLSFSTCAEYLVSSSNTE 251
Query: 247 TLHVFEVFNDA 257
T+H+F + A
Sbjct: 252 TVHIFRLDRSA 262
>Hs22064307 [S] KOG2111 Uncharacterized conserved protein contains WD40 repeats
Length = 352
Score = 63.2 bits (152), Expect = 5e-10
Identities = 34/95 (35%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Query: 191 GDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAVVSDKWTLHV 250
G +AT S+ GTLI +F T +G L++E RRG +I + ++ D S + V SD T+H+
Sbjct: 205 GTRIATASEKGTLIGIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHI 264
Query: 251 FEVFNDAENKRHVLKDWINI-KYFQSEWSICNFKL 284
F + NK+ L + KYF +WS F++
Sbjct: 265 FAAEDLKRNKQSSLASASFLPKYFSYKWSFSKFQV 299
>Hs7706294 [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 438
Score = 62.8 bits (151), Expect = 7e-10
Identities = 55/222 (24%), Positives = 100/222 (44%), Gaps = 18/222 (8%)
Query: 43 HPLKRIMSQEMPDAGTIRMLHRTNYIAFVSTKK-ELLHIWDDVKKQDITRVKLDAAVKDL 101
H L ++S + D + L ++ +A VS K L + K +I + +
Sbjct: 58 HVLPFVISADTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAV 117
Query: 102 FLSREFIVVSQGDVISIFKFGNPWNKITEDIKF-----GGVCEFA----NGLLVYSNEFN 152
L+R+ ++V + + I + K+ I+ G+C + N L Y
Sbjct: 118 KLNRQRLIVCLEESLYIHNIRDM--KVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 175
Query: 153 LGQIHVTRLQTDAEQVVGKGVLVKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNG 212
+G++ V + ++ AH +P+ + + G +AT S+ GT+IRVF G
Sbjct: 176 IGEVQVFDTIN-----LRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG 230
Query: 213 VLVREFRRGLDR-TSIIDMRWSPDGSKLAVVSDKWTLHVFEV 253
+ EFRRG+ R SI + +S DG L+ S+ T+H+F++
Sbjct: 231 QKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKL 272
>Hs7661580 [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 454
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/231 (24%), Positives = 104/231 (44%), Gaps = 19/231 (8%)
Query: 35 KSFDIYNVHPLKRIMS-QEMPDAGTIRMLHRTNYIAFVSTKK-ELLHIWDDVKKQDITRV 92
K F + +V L++I + D + L ++ +A VS K L + K +I
Sbjct: 54 KFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNY 113
Query: 93 KLDAAVKDLFLSREFIVVSQGDVISIFKFGNPWNKITEDIKF-----GGVCEFA----NG 143
+ + L+R+ ++V + + I + K+ I+ G+C + N
Sbjct: 114 SYSNTILAVKLNRQRLIVCLEESLYIHNIRDM--KVLHTIRETPPNPAGLCALSINNDNC 171
Query: 144 LLVYSNEFNLGQIHVTRLQTDAEQVVGKGVLVKAHANPVKMVRLNRKGDMVATCSQDGTL 203
L Y +G++ V + ++ AH +P+ + + G +AT S+ GT+
Sbjct: 172 YLAYPGSATIGEVQVFDTIN-----LRAANMIPAHDSPLAALAFDASGTKLATASEKGTV 226
Query: 204 IRVFQTDNGVLVREFRRGLDR-TSIIDMRWSPDGSKLAVVSDKWTLHVFEV 253
IRVF G + EFRRG+ R SI + +S DG L+ S+ T+H+F++
Sbjct: 227 IRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKL 277
>YFR021w [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 500
Score = 60.1 bits (144), Expect = 5e-09
Identities = 28/89 (31%), Positives = 50/89 (55%)
Query: 173 VLVKAHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRW 232
++++AH + + ++ G ++AT S GT+IRVF + G + +FRRG T I + +
Sbjct: 239 MVIEAHKGEIAAMAISFDGTLMATASDKGTIIRVFDIETGDKIYQFRRGTYATRIYSISF 298
Query: 233 SPDGSKLAVVSDKWTLHVFEVFNDAENKR 261
S D LAV T+H+F++ + N +
Sbjct: 299 SEDSQYLAVTGSSKTVHIFKLGHSMSNNK 327
>SPAC589.07c [S] KOG2110 Uncharacterized conserved protein contains WD40 repeats
Length = 373
Score = 59.3 bits (142), Expect = 8e-09
Identities = 60/262 (22%), Positives = 107/262 (39%), Gaps = 34/262 (12%)
Query: 29 LIVSTPKSFDIYNVHPLKRIMSQEMPDAGTIRMLHRTNYIAFVST---KKELLHIWDDVK 85
L + T + IYN P + + + ML T+ +A V L + + K
Sbjct: 15 LSIGTFDGYKIYNCDPFGKCFHKIQGATSIVEMLFSTSLVALVEKDDGNNRKLKLINTKK 74
Query: 86 KQDITRVKLDAAVKDLFLSREFIVVSQGDVISIFKFGNPW--NKITEDIKFGGVCEFA-- 141
I + + + L+R+ ++ + I ++ N + I VC +
Sbjct: 75 STTICELTFPTPLLAVKLNRKRLLAVLEEQIYVYDISNMLLLHTIETTSNVFAVCALSPN 134
Query: 142 --NGLLVYSNEFNLGQIHVTRLQTDAEQ-------VVGKGVL-----------VKAHANP 181
N L Y + + H R + ++ V G+ +L ++AH +
Sbjct: 135 SENCYLAYPDSRD----HEPRTEGESSSPNVSNSAVSGQVILWDVINCKQITKIEAHKDS 190
Query: 182 VKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDGSKLAV 241
+ + N G M+AT S +G +IRVF +G + +FRRG I + + PD S L V
Sbjct: 191 LACLAFNSDGTMLATASDNGRIIRVFAIPSGQRLYQFRRGSLPAQIYSIAFHPDSSLLTV 250
Query: 242 VSDKWTLHVF---EVFNDAENK 260
S T+H+F EV+++ E +
Sbjct: 251 TSSTQTVHIFRLKEVYSNLERQ 272
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.138 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,308,019
Number of Sequences: 60738
Number of extensions: 904780
Number of successful extensions: 2293
Number of sequences better than 1.0e-05: 21
Number of HSP's better than 0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2246
Number of HSP's gapped (non-prelim): 24
length of query: 339
length of database: 30,389,216
effective HSP length: 107
effective length of query: 232
effective length of database: 23,890,250
effective search space: 5542538000
effective search space used: 5542538000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)