ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4324 check: MH R KOG0509 General function prediction only Ankyrin repeat and DHHC-type Zn-finger domain containing proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4324 1484752 1487007 752
(752 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR264c [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 642 0.0
YOR034c [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 428 e-119
SPAC2F7.10 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger do... 207 4e-53
Hs22060186 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger do... 186 1e-46
7294202 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 150 5e-36
Hs9506623 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger dom... 132 1e-30
CE21005 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 111 5e-24
At5g20350 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger dom... 93 1e-18
CE02585 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 81 7e-15
Hs10947056 [M] KOG4177 Ankyrin 74 1e-12
Hs20538133 [R] KOG0504 FOG: Ankyrin repeat 72 3e-12
Hs4502093 [M] KOG4177 Ankyrin 72 4e-12
7298956 [R] KOG0510 Ankyrin repeat protein 72 4e-12
Hs14731279 [R] KOG0504 FOG: Ankyrin repeat 71 7e-12
7304338 [M] KOG4177 Ankyrin 71 7e-12
Hs13376842 [M] KOG4177 Ankyrin 70 9e-12
7295202 [M] KOG4177 Ankyrin 70 1e-11
Hs7657238 [R] KOG0504 FOG: Ankyrin repeat 70 2e-11
Hs4507613 [M] KOG4177 Ankyrin 68 5e-11
CE07175 [R] KOG0508 Ankyrin repeat protein 68 5e-11
Hs4506217 [O] KOG4412 26S proteasome regulatory complex subunit ... 68 6e-11
7297920 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 67 1e-10
7299952 [R] KOG0508 Ankyrin repeat protein 65 3e-10
Hs10947054 [M] KOG4177 Ankyrin 64 9e-10
Hs10947052 [M] KOG4177 Ankyrin 64 9e-10
7294194 [OT] KOG0505 Myosin phosphatase regulatory subunit 64 9e-10
CE06705 [M] KOG4177 Ankyrin 63 1e-09
CE06704 [M] KOG4177 Ankyrin 63 1e-09
CE06703 [M] KOG4177 Ankyrin 63 1e-09
CE06702 [M] KOG4177 Ankyrin 63 1e-09
Hs22064845 [T] KOG0192 Tyrosine kinase specific for activated (G... 62 3e-09
Hs17864094 [R] KOG0508 Ankyrin repeat protein 62 3e-09
At1g07710 [R] KOG0504 FOG: Ankyrin repeat 61 6e-09
Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 61 7e-09
Hs10947042 [M] KOG4177 Ankyrin 60 9e-09
Hs10947040 [M] KOG4177 Ankyrin 60 9e-09
Hs10947038 [M] KOG4177 Ankyrin 60 9e-09
Hs10947036 [M] KOG4177 Ankyrin 60 9e-09
Hs4557799 [T] KOG1217 Fibrillins and related proteins containing... 60 1e-08
Hs14249672 [OT] KOG0505 Myosin phosphatase regulatory subunit 60 1e-08
At2g14250 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger dom... 60 2e-08
CE26238_1 [M] KOG4177 Ankyrin 59 3e-08
Hs18551475 [R] KOG0504 FOG: Ankyrin repeat 59 4e-08
Hs14770818 [OT] KOG0505 Myosin phosphatase regulatory subunit 59 4e-08
7301689 [R] KOG0504 FOG: Ankyrin repeat 59 4e-08
7290390 [T] KOG1217 Fibrillins and related proteins containing C... 59 4e-08
7294199_2 [R] KOG0504 FOG: Ankyrin repeat 59 4e-08
Hs14744423 [R] KOG0504 FOG: Ankyrin repeat 58 5e-08
Hs13540484 [R] KOG0504 FOG: Ankyrin repeat 58 5e-08
Hs21264330_2 [R] KOG0504 FOG: Ankyrin repeat 58 5e-08
7298524_2 [R] KOG0504 FOG: Ankyrin repeat 58 6e-08
ECU10g0720 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger do... 57 8e-08
7301359 [M] KOG4177 Ankyrin 57 8e-08
Hs6601590 [R] KOG0510 Ankyrin repeat protein 57 1e-07
Hs14720884 [R] KOG0504 FOG: Ankyrin repeat 57 1e-07
CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 57 1e-07
Hs14764060 [R] KOG0508 Ankyrin repeat protein 57 1e-07
7291939 [R] KOG0510 Ankyrin repeat protein 57 1e-07
CE05814 [R] KOG0502 Integral membrane ankyrin-repeat protein Kid... 56 2e-07
CE05333 [R] KOG0510 Ankyrin repeat protein 56 2e-07
Hs18561834 [M] KOG4177 Ankyrin 56 2e-07
CE00274 [T] KOG1217 Fibrillins and related proteins containing C... 55 3e-07
7301583 [R] KOG0504 FOG: Ankyrin repeat 55 4e-07
Hs7656961 [R] KOG0504 FOG: Ankyrin repeat 55 5e-07
Hs13129098 [R] KOG0504 FOG: Ankyrin repeat 55 5e-07
At3g04710_1 [R] KOG0504 FOG: Ankyrin repeat 55 5e-07
YIL112w [R] KOG0504 FOG: Ankyrin repeat 54 7e-07
CE27598 [R] KOG0504 FOG: Ankyrin repeat 54 1e-06
Hs22047178 [R] KOG0504 FOG: Ankyrin repeat 53 2e-06
Hs21450703 [R] KOG0504 FOG: Ankyrin repeat 53 2e-06
Hs14149971 [R] KOG0504 FOG: Ankyrin repeat 53 2e-06
At5g60070 [R] KOG0504 FOG: Ankyrin repeat 53 2e-06
HsM14249476 [R] KOG1311 DHHC-type Zn-finger proteins 53 2e-06
Hs7662406 [R] KOG0504 FOG: Ankyrin repeat 53 2e-06
Hs21361910 [R] KOG1311 DHHC-type Zn-finger proteins 53 2e-06
Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 53 2e-06
Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 53 2e-06
Hs16159328 [R] KOG0504 FOG: Ankyrin repeat 53 2e-06
CE23926 [T] KOG4369 RTK signaling protein MASK/UNC-44 53 2e-06
CE19676 [R] KOG0504 FOG: Ankyrin repeat 53 2e-06
CE06305 [T] KOG4369 RTK signaling protein MASK/UNC-44 53 2e-06
Hs16076877 [R] KOG0504 FOG: Ankyrin repeat 52 3e-06
Hs14150169 [I] KOG0817 Acyl-CoA-binding protein 52 3e-06
Hs13375989 [R] KOG0504 FOG: Ankyrin repeat 52 3e-06
7291279 [R] KOG0502 Integral membrane ankyrin-repeat protein Kid... 52 3e-06
Hs7705831 [R] KOG0504 FOG: Ankyrin repeat 52 4e-06
Hs10190676_2 [R] KOG0504 FOG: Ankyrin repeat 52 4e-06
Hs22054847_2 [R] KOG0504 FOG: Ankyrin repeat 51 6e-06
Hs20472035 [R] KOG0504 FOG: Ankyrin repeat 51 7e-06
Hs18252778 [R] KOG0504 FOG: Ankyrin repeat 51 7e-06
Hs13249344 [T] KOG1217 Fibrillins and related proteins containin... 51 7e-06
CE16523 [R] KOG0504 FOG: Ankyrin repeat 51 7e-06
At5g40160 [R] KOG0504 FOG: Ankyrin repeat 51 7e-06
At2g03430 [O] KOG4412 26S proteasome regulatory complex subunit ... 51 7e-06
CE16688 [R] KOG0504 FOG: Ankyrin repeat 50 1e-05
>YDR264c [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 764
Score = 642 bits (1656), Expect = 0.0
Identities = 342/771 (44%), Positives = 479/771 (61%), Gaps = 47/771 (6%)
Query: 2 TAEEVDKESDPAIEDVKSDYDAIELGXXXXXXXXVVSLDSMKAVISRASSELKHENDQGE 61
T ++ DP+ D + D I LG + SL S+KA+ R+ +E + N+Q
Sbjct: 13 TLTNEEQTVDPSNNDSQED---ISLGDSNE----ITSLASLKAI--RSGNEEESGNEQVN 63
Query: 62 ERDLGSVEKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNR 121
D E+DP+L RYH AC++GD+ T++EM+ K+++++ND D E ++GLHWA INNR
Sbjct: 64 HND--EAEEDPLLTRYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNR 121
Query: 122 LSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLH 181
LS V +L GA+VN + G L ATPLHWA++ G VYIVD LLK GADP +TD QG+NLLH
Sbjct: 122 LSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLH 181
Query: 182 TSVFSSNIMLVIYVLFFVVD-GKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVK 240
SV SSNIMLV+YVLF VV G D+D DP RT+L WA YQ D+LTV LLKF A +K
Sbjct: 182 LSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIK 241
Query: 241 NADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLY 300
AD GFT LHWGTVKG V+ LI+ G+DFFQ T+ GK+CF I +E+ ++ SL +L
Sbjct: 242 IADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLREALT 301
Query: 301 KNGFDKNGFPLPQYFSAST-GKMLTFFLPWVLIPLVFYIFSKITFFIALLINTIVLVISG 359
+GFD +G+P+ ++F S K++TF P++ + + F +FS I +++ ++ + +
Sbjct: 302 HSGFDYHGYPIKKWFKKSQHAKLVTFITPFLFLGIAFALFSHINPLFVIIVLFLLAIATN 361
Query: 360 LVLSRLVVPSYLLSKRH--PILNSPLLAGILSGTIAIAFFIWFTKISILTFTEKPVGNII 417
L++ V+PSY H +L SPLL+G+ GT+ +WF K+ TF+++ NI+
Sbjct: 362 KGLNKFVLPSYGRMGVHNVTLLRSPLLSGVFFGTLLWVTIVWFFKVMPRTFSDEQYTNIL 421
Query: 418 MLGFFIGLITLFIGLMKSDPGYIPGTVDHDKVRETIKELLSLGKFDAKHFCVHTWIRIPL 477
ML + + LF L+ DPG +P DH+ VR+TI LL +GKFD K+FC+ TWIR PL
Sbjct: 422 MLVILVSVFYLFGQLVIMDPGCLPEETDHENVRQTISNLLEIGKFDTKNFCIETWIRKPL 481
Query: 478 RSKYDRDSACLISAFDHFCPWVYNQIGLLNHKLFYMFVVLLEISVWWFLPLMMEYFDELE 537
RSK+ + +++ FDH+CPW++N +GL NHK F F+ L+E ++ FL L +EYFDELE
Sbjct: 482 RSKFSPLNNAVVARFDHYCPWIFNDVGLKNHKAFIFFITLMESGIFTFLALCLEYFDELE 541
Query: 538 DYLENRKGKHFGDCHFLGDEDLCFGLHHDTFNFLLLCWVIFQAFWVLCLIAVQTVQMLKG 597
D E+ K+ G C LG DLC GL +D F FL+L W + Q+ WV LI VQ Q+ KG
Sbjct: 542 DAHEDTSQKN-GKCFILGASDLCSGLIYDRFVFLILLWALLQSIWVASLIFVQAFQICKG 600
Query: 598 VTDYEFVQINKKLKS---NGTTTEDIFSSTPPELMSEELIAELDAPALDPRQ-------- 646
+T+ EF + K+ KS +G + + F++TP E AP++DP +
Sbjct: 601 MTNTEFNVLMKESKSIGPDGLSFNENFNTTP----------EGFAPSIDPGEESNDTVLA 650
Query: 647 -VP------QRTCFTVCCTLLGLDKLVTMIKSVLRLKSDEPXXXXXXXXXXXXIPTDYGW 699
VP RTCF VC + G+D+ + +IK + +K IPT+YGW
Sbjct: 651 PVPGSTIRKPRTCFGVCYAVTGMDQWLAVIKETIGIKD---STGHNVYSITSRIPTNYGW 707
Query: 700 KQNLKDFWLLPDTSSPLWRRILLPPKDSHALLNGMEVDYYTLYTLPNATEE 750
K+N+KDFWL D ++PLWRRIL PP S ALLNG+EVDY+ LY LPN E
Sbjct: 708 KRNVKDFWLTSDINAPLWRRILYPPSGSKALLNGIEVDYFKLYKLPNKDVE 758
>YOR034c [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 749
Score = 428 bits (1100), Expect = e-119
Identities = 247/734 (33%), Positives = 396/734 (53%), Gaps = 32/734 (4%)
Query: 44 AVISRASSELKHENDQGEERDLGSVEK-DPILERYHAACKQGDMKTLREMVESKVIDLSN 102
AV++ + ++D + + LG + +++ + A K GD+K ++++VES +D++N
Sbjct: 20 AVVTDVAQHAVSDSDNNKAQLLGDGSNTEYVVDIFIEAAKDGDLKVVKDVVESGAVDINN 79
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
D + +SGLHWACINNR S K+L GA N G AT LHWA++ G +YIVD L
Sbjct: 80 DRI--DELSGLHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLL 137
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE--DVDQPDPHQRTALQWA 220
LK GADP + D QG N++H SV+SSNI+LV+YVL+FVV+ + D+D D + RT L WA
Sbjct: 138 LKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWA 197
Query: 221 TYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGK 280
YQ D LTVE LLKF + V D+ GF ALH V G V+ LI G++F++ N +
Sbjct: 198 AYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANFYERNNQKQ 257
Query: 281 NCFTIGKELYSIGSLEASLYKNGFDKNGFPLPQYFSASTGKMLTFFL-PWVLIPLVFYIF 339
+CF + + + + E +L +G+D+ G + F S+ T FL P++L+ ++ I
Sbjct: 258 DCFDLAEGMGTKSLFEQALQHHGYDRLGNQKDKLFKKSSHAQFTIFLSPFLLMVYIYLIS 317
Query: 340 SKITFFIALLINTIVLVISGLVLSRLVVPSYLLSKRHPI--LNSPLLAGILSGTIAIAFF 397
++ +A++++ +V V+ L + V+P + + +P +G+ T +
Sbjct: 318 LVLSPVLAIMLSLLVTVVMVNTLKKFVLPCLPRKNTYKVSLTRTPFFSGLFLSTFCFLIY 377
Query: 398 IWFTKISILTFTEKPVGNIIMLGFFIGLITLFIGLMKSDPGYIPGTVDHDKVRETIKELL 457
IW K+ + ++ + N+ L + LF+ L++SDPG + ++ETIK+L+
Sbjct: 378 IWTKKLYPYSVSDYTMKNVQFLVTSFLTVVLFLRLVRSDPGCLKTDDSLTSIQETIKQLI 437
Query: 458 SLGKFDAKHFCVHTWIRIPLRSKYDRDSACLISAFDHFCPWVYNQIGLLNHKLFYMFVVL 517
LGKFD ++FCV T R PLRSKY S L++ +DH+CPW+YN +GL NHKLF F V
Sbjct: 438 DLGKFDRENFCVETLERKPLRSKYSFFSGALVARYDHYCPWIYNDVGLKNHKLFVFFAVT 497
Query: 518 LEISVWWFLPLMMEYFDELEDYLENRKGKHFGDCHFLGDEDLCFGLHHDTFNFLLLCWVI 577
++ ++ F+ L + YF + E + + + C L +E LC G ++D F L W+
Sbjct: 498 VQYHMFLFMWLCLAYFKKTNYIYE--QVEEYARCALLKNETLCKGSNYDPSTFFLFIWIS 555
Query: 578 FQAFWVLCLIAVQTVQMLKGVTDYE-FVQINKKLKSNGTT----TEDIFSSTPPELMSEE 632
W+ ++ VQ Q+LKG+T E F+ I ++ K+ I++S + +
Sbjct: 556 VNFIWLGAMLIVQFFQILKGITTPELFILIKEEHKAKFINLIPFENSIYTSESKGVEDSD 615
Query: 633 LIAE----------LDAPALDPRQVPQRTCFTVCCTLLGLDKLVTMIKSVLR----LKSD 678
+I E + L+PR +R + C +++G+++ + IK ++ L
Sbjct: 616 MIPEGPSATTITHTISIDGLEPRN-RRRAILSACFSMMGINQWLVTIKEIVGITHILHGQ 674
Query: 679 EPXXXXXXXXXXXXIPTDYGWKQNLKDFWLLPDTSSPLWRRILLPPKDSHALLNGMEVDY 738
P + WK NL DFWL D ++PLW+R S A+L G EVDY
Sbjct: 675 VPQQHHSSLLRSFLVTNH--WKTNLTDFWLNSDVTAPLWQRFFYSSDTSKAMLGGTEVDY 732
Query: 739 YTLYTLPNATEELV 752
Y LY P E++
Sbjct: 733 YELYEYPAREGEVL 746
>SPAC2F7.10 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 642
Score = 207 bits (528), Expect = 4e-53
Identities = 158/546 (28%), Positives = 255/546 (45%), Gaps = 65/546 (11%)
Query: 80 ACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKG 139
A QG++ T++ ++ S+ ID++ + + LHWA +N ++ K+L GA+VN G
Sbjct: 7 AASQGELDTVKNLISSEKIDVNAT--DEGGATALHWAALNQQIPICKFLLEHGADVNAIG 64
Query: 140 GELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFV 199
G+L A P+HWA+K G V V L++ GADP + D QG+N LH +V +++ +LV+Y+L
Sbjct: 65 GDLQAAPIHWAAKRGSVKTVHYLVQHGADPLLKDKQGFNCLHLAVHAASPLLVVYLLHLD 124
Query: 200 VDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSI 259
+ VD D Q T L WA+Y + LL++ ADV D+ T LHW V G++
Sbjct: 125 I----SVDLRDDQQHTPLMWASYHGNEPITNCLLRWGADVLATDEDKMTPLHWSIVGGNL 180
Query: 260 PVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGS-LEAS-LYKNGFDKNGFPLPQYFSA 317
M L++K G T N K +++ S L S L+K NG + +
Sbjct: 181 KCMKLILKEGG--IPCTAVTANLSGQLKTPWALASELRVSHLFKQALISNGLKVKETSEE 238
Query: 318 STGKMLTFFLPWVLIPLVFYIFSKITFFIALLINTIVLV--------ISGLVLSRLVVPS 369
WV++P F FS+ TF I +++ ++ I +V+S ++ P
Sbjct: 239 PE--------KWVVVPSKFQ-FSQKTFIIFCFLSSFIITGVFFFIMSICPMVISLIIAPL 289
Query: 370 YL--------------LSKRHPILNSPLLAGILSGTIAIAFFIWFTKISIL---TFTEKP 412
++ + H L +P LAGI S +I F++W + + T KP
Sbjct: 290 WIYFTFKYITTCIHANIDIVHFYLETPFLAGIFS---SIFFWVWCHSLLYIVPKTLPIKP 346
Query: 413 VGNIIMLGFFIGLITLFIGLMKSDPGYIPGTVDHDKVRETIKELLSLGKFDAKHFCVHTW 472
+ +++ + I L++ +PGY+ + RE I +LL F+ H+C+ +
Sbjct: 347 LSSLLFVLISFTCIGLYVRTAFQNPGYVDKIGAVVQRREEISKLLDKDLFNQSHYCLKCF 406
Query: 473 IRIPLRSKYDRDSACLISAFDHFCPWVYNQIGLLNHKLFYMFVVLLEISVWWFLPLMMEY 532
P RS + I+ +DH CPW N +G NH+ F +FV L L+ Y
Sbjct: 407 QVKPPRSYHCGACKRCINRYDHHCPWTGNCVGARNHRTFLLFVFTLS-------TLIPIY 459
Query: 533 FDELEDYLEN---RKGKHFGDCHFLGDEDLCFGLHHDTF-------NFLLLCWVIFQAFW 582
F YL+N +K C F+ +C D F F+ CWV+ AF
Sbjct: 460 FYVAFYYLQNIPIQKKYESYRCLFISG-TICQWSLKDMFVLVASLTLFVNWCWVVVLAFT 518
Query: 583 VLCLIA 588
+C +A
Sbjct: 519 QICQVA 524
>Hs22060186 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 632
Score = 186 bits (472), Expect = 1e-46
Identities = 141/464 (30%), Positives = 217/464 (46%), Gaps = 33/464 (7%)
Query: 80 ACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKG 139
A + G + RE+VE+ D KE V+ LHWA INNR+ VKY GA V+ G
Sbjct: 64 ATQYGIYERCRELVEAGYDVRQPD---KENVTLLHWAAINNRIDLVKYYISKGAIVDQLG 120
Query: 140 GELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFV 199
G+L++TPLHWA++ G + +V +L+K GADP++ D +G + +H + + +V Y +
Sbjct: 121 GDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAY----L 176
Query: 200 VDGKEDVDQPDPHQRTALQWATYQADAL-TVENLLKFNADVKNADD-AGFTALHWGTVKG 257
+ +DVD D + T L WA Y+ ++ LL FN V D TALHW + G
Sbjct: 177 IAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAG 236
Query: 258 SIPVMDLLIKHGSDFFQTTNDGKNCFTIGKE---LYSIGSLEASLYKNGFDKNGFPLPQY 314
+ V+ LL++ G++ G++ + K+ ++ I L+ + G+D F
Sbjct: 237 NTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLK 296
Query: 315 FSASTGKMLTFFLPWVLIPLVFYIFSKITFFIALLINTIVLVISGLVLSRLVVPSYLLSK 374
+ + P+++I LV +I +N +I GL+ + LSK
Sbjct: 297 ADKEFRQKVMLGTPFLVIWLVGFIAD---------LNIDSWLIKGLMYGGVWATVQFLSK 347
Query: 375 R--HPILNSPLLAGILSGT---IAIAFFIWFTKISILTFTEKPVGNIIMLGFFIGLITLF 429
++S L GI T + + +F WF F P L + L F
Sbjct: 348 SFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLP-----FLANSVALFYNF 402
Query: 430 IGLMKSDPGYIPGTVDHDKVRETIKELLSLGKFDAKHFCVHTWIRIPLRSKYDRDSACLI 489
KSDPG I T + K +TI EL G D FC IR P+RSK+ I
Sbjct: 403 GKSWKSDPGIIKATEEQKK--KTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCI 460
Query: 490 SAFDHFCPWVYNQIGLLNHKLFYMFVVLLEISVWWFLPLMMEYF 533
+ FDH CPWV N +G NH+ F ++ L + W + + Y+
Sbjct: 461 AKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYW 504
>7294202 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 637
Score = 150 bits (380), Expect = 5e-36
Identities = 154/534 (28%), Positives = 235/534 (43%), Gaps = 55/534 (10%)
Query: 80 ACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKG 139
A + G + +RE+VES + E V+ LHWA INNR ++Y GA V+ G
Sbjct: 52 ATQYGAIARVRELVES---GWDVNQPDSETVTLLHWAAINNRRDIIRYFLEKGATVDAVG 108
Query: 140 GELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFV 199
GEL+ATPLHWA++ G + V L+ AGADP I D++G + +H + ++ LV Y F+
Sbjct: 109 GELNATPLHWATRQGHLGAVVLLMAAGADPRIRDAEGCSCIHIAAQFAHTALVAY---FI 165
Query: 200 VDGKEDVDQPDPHQRTALQWATYQADAL-TVENLLKFNADVKNAD-DAGFTALHWGTV-K 256
G D D D TAL WA ++ AL V LL A+ D G TALHW + +
Sbjct: 166 AKG-VDPDLQDRGGMTALMWAAWKVCALDPVRLLLTLGANPAMVDYTHGNTALHWAILAR 224
Query: 257 GSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYS---IGSLEASLYKNGFDKNGFPLPQ 313
+ + L++K + G+ ++ + IG+ K +
Sbjct: 225 NATAISTLVLKSKASLDVPNLRGETPLSMLESQTGAIWIGAKVMDRVKEAALTSQQRRSL 284
Query: 314 YFSASTGKMLTFFLPWVLIPLVFYIFSKITFFIALLINTIVLVISGLVLSRLVVPSYLLS 373
K L + W ++ F F++A IV ++ L + + + L S
Sbjct: 285 LSKLRHDKRLRW---WSMVACPF-----TAFYLA----GIVFTVNTLYIIKFFLLGCLYS 332
Query: 374 KRHPI---LNSPLLAGILSGTIAIAFFIWFTKISILTFTEKPVGNIIMLGFFIGLITLFI 430
H I L L +L ++ +A WF ++ L + + V + F I + L++
Sbjct: 333 IFHTIGKALFDEHLMALLPLSVYLATKAWF-YVTWLMYIDDAVSFTATVCFLISSLLLWV 391
Query: 431 GLMKS---DPGYIPGTVDHDKVRETIKELLSLG--KFDAKHFCVHTWIRIPLRSKYDRDS 485
+KS DPG I T ++ +TI EL G F+ FC +R P+RSK+
Sbjct: 392 CFLKSWKGDPGIIRPT--REQRFKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVC 449
Query: 486 ACLISAFDHFCPWVYNQIGLLNHKLFYMFVVLLEISVWWFLPLMMEYFDELEDYLENRKG 545
++ FDH CPWV N IGL NH F F+ +L I W L +Y+ + R
Sbjct: 450 DRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYY---VNQCNVRFD 506
Query: 546 KHFGDCHFLGDEDLCFGLHHDTFNFLLLCWVIFQAF----WVLCLIAVQTVQML 595
G +G+ D G WV+ A WV+ L QT Q++
Sbjct: 507 DFLGAMRAIGNCDAWVG------------WVMGNALLHMSWVILLTICQTYQVI 548
>Hs9506623 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 481
Score = 132 bits (333), Expect = 1e-30
Identities = 117/456 (25%), Positives = 196/456 (42%), Gaps = 46/456 (10%)
Query: 80 ACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKG 139
A + G + +E+VE+ D KE VS LHWA INNRL V++ GA V+ G
Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPD---KENVSLLHWAAINNRLDLVRFYISKGAVVDQLG 112
Query: 140 GELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFV 199
G+L++TPLHWA + G + +V LL+ GADP + D +G++ +H +V ++ ++ Y +
Sbjct: 113 GDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAY----L 168
Query: 200 VDGKEDVDQPDPHQRTALQWATYQADALTVEN-LLKFNADVKNADDA-GFTALHWGTVKG 257
+ + V+ D + +T L + ++ LLKFN + D T LHW G
Sbjct: 169 ISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAG 228
Query: 258 SIPVMDLLIKHGSDFFQTTNDGKNCFTIGKE-----LYSIGSLEASLYKNGFDKNGFPLP 312
++ +D L++ GS G+ + + + + EA + N F L
Sbjct: 229 NVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRAN----QKFRLW 284
Query: 313 QYFSASTGKMLTFFLPWVLIPLVFYIFSKITFFIALLINTIVLVISGLVLSRL-----VV 367
++ + FL +L + + I F N+ ++ G +L L +
Sbjct: 285 RWL-----QKCELFLLLMLSVITMWAIGYILDF-----NSDSWLLKGCLLVTLFFLTSLF 334
Query: 368 PSYLLSKRHPILNSPLLAGILSGTIAIAFFIWFTKISILTFTEKPVGNIIMLGFFIGLIT 427
P +L+ ++ + L L ++ F WF + F G F ++
Sbjct: 335 PRFLVGYKNLVY---LPTAFLLSSVFWIFMTWF-----ILFFPDLAGAPFYFSFIFSIVA 386
Query: 428 ---LFIGLMKSDPGYIPGTVDHDKVRETIKELLSLGKFDAKHFCVHTWIRIPLRSKYDRD 484
F +DPG+ + + KV I L G D + FC IR PLRS +
Sbjct: 387 FLYFFYKTWATDPGFTKASEEEKKV--NIITLAETGSLDFRTFCTSCLIRKPLRSLHCHV 444
Query: 485 SACLISAFDHFCPWVYNQIGLLNHKLFYMFVVLLEI 520
C ++ +D C W IG NH + F+ L +
Sbjct: 445 CNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSM 480
>CE21005 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 783
Score = 111 bits (277), Expect = 5e-24
Identities = 117/495 (23%), Positives = 212/495 (42%), Gaps = 79/495 (15%)
Query: 65 LGSVEKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSA 124
L E D + + AC+ G+++T+R ++ V +N++D E LHWA INN+L
Sbjct: 137 LRGAEMDSKMHQAVRACQIGEIQTVRFLLNGHVS--ANEFD-HEGCGLLHWAAINNKLDI 193
Query: 125 VKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSV 184
++ L A++N GG + +TPLHWA + V L+K GADP I + G LH +
Sbjct: 194 IQLLLSHRADINLIGGNMKSTPLHWACYNSQFGAVMALVKNGADPTIKNINGETPLHLAA 253
Query: 185 FSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADAL-TVENLLKFNADVKNAD 243
+ N +++ Y+L V D D R+AL A ++ L + K +A + D
Sbjct: 254 CTGNFIIIAYLL---VKFDNIKDTRDNLGRSALMMAADKSFGLFPIRIFTKVDAYLDFTD 310
Query: 244 D-AGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTI--------------GKE 288
D G TALH + ++ + LI G+D +T N+G + + +
Sbjct: 311 DEKGNTALHILAARQNLKGVVELICSGADDTKTDNNGVSARDLMDNKFRNLVDKQVTARN 370
Query: 289 LYSIGSLEASLYKNGFDKNGFPLPQYFSASTGKMLTFFL---PWVLIPLVFYIFSKITFF 345
+ +G++ + F L Q+F+A+ L F+ V+I ++ F+
Sbjct: 371 ICELGTICEKVTSRWF------LGQFFTATISGYLAFYFTIKDCVMIGAATGLYFLTNFW 424
Query: 346 IALLINTIVLVISGLVLSRLVVPSYLLSKRHPILNSPLLAGILSGTIAIAFFIW--FTKI 403
+ V+ GL L+ L++ ++L +R + G + + + W +
Sbjct: 425 V---------VLGGLALTALLL--FILVQRRQMDQ--------FGCLPVTYIFWMGIAEF 465
Query: 404 SILTFTEKPVGN-----------IIMLGFFIGLITLFI-------GLMKSDPGYIPGTVD 445
++L F + + +I F+ + T + L+ ++PG +P +
Sbjct: 466 ALLIFNSNGLVHWSVLIFVCSIWVISASFYWIMFTTILRIDYIDFSLILTNPGVLPRST- 524
Query: 446 HDKVRETIKELLSLGKFDAKHFCVHTWIRIPLRSKYDRDSAC--LISAFDHFCPWVYNQI 503
++ IK+ L + +C W IP S S C + FDH CPW++ +
Sbjct: 525 -TPFKDFIKD---LEEKQIDRYCFTCW--IPKTSSSHHCSQCDKCVDGFDHHCPWIHKCV 578
Query: 504 GLLNHKLFYMFVVLL 518
N + F F + +
Sbjct: 579 YRKNLRAFVFFCLTI 593
>At5g20350 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 592
Score = 93.2 bits (230), Expect = 1e-18
Identities = 59/212 (27%), Positives = 98/212 (45%), Gaps = 7/212 (3%)
Query: 58 DQGEERDLGSVEKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWAC 117
+ GE G +E++ + + A GD++ L +VE + +S L W+
Sbjct: 17 ENGESSSKG-IEEESLKNDVYTAAAYGDLEKLHRLVECEGSSVSE--PDALGYYALQWSA 73
Query: 118 INNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGY 177
+NNR++ +YL G +VN T LHW++ G + + + LL+ GA + TD GY
Sbjct: 74 LNNRVAVAQYLIEHGGDVN-ATDHTGQTALHWSAVRGAIQVAELLLQEGARVDATDMYGY 132
Query: 178 NLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNA 237
H + + +V V D D PD R+ L WA Y+ A ++ LL +A
Sbjct: 133 QATHVAAQYGQTAFLCHV---VSKWNADPDVPDNDGRSPLHWAAYKGFADSIRLLLFLDA 189
Query: 238 DVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
D G T LHW ++G++ +L++ G
Sbjct: 190 YRGRQDKEGCTPLHWAAIRGNLEACTVLVQAG 221
Score = 51.2 bits (121), Expect = 6e-06
Identities = 24/65 (36%), Positives = 35/65 (52%)
Query: 206 VDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLL 265
V +PD ALQW+ + L++ DV D G TALHW V+G+I V +LL
Sbjct: 58 VSEPDALGYYALQWSALNNRVAVAQYLIEHGGDVNATDHTGQTALHWSAVRGAIQVAELL 117
Query: 266 IKHGS 270
++ G+
Sbjct: 118 LQEGA 122
Score = 50.8 bits (120), Expect = 7e-06
Identities = 36/117 (30%), Positives = 55/117 (46%), Gaps = 15/117 (12%)
Query: 413 VGNIIMLGFFIGLITLFI--GLMKSDPGYIPGTVDHDKVRETIKELLSLGKFDAKH---- 466
+G + LGF + LF+ + DPGYI + HD +T+K+ L K + +
Sbjct: 281 IGALAWLGFILATAGLFLFYRCSRKDPGYIRMNI-HDP--QTMKDDEPLLKIELNNPALL 337
Query: 467 ------FCVHTWIRIPLRSKYDRDSACLISAFDHFCPWVYNQIGLLNHKLFYMFVVL 517
C I PLR+K+ + FDH CPWV N +G N F++F++L
Sbjct: 338 AGNWTQLCATCKIIRPLRAKHCSTCDRCVEQFDHHCPWVSNCVGKKNKWEFFLFLLL 394
>CE02585 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 209
Score = 80.9 bits (198), Expect = 7e-15
Identities = 56/179 (31%), Positives = 86/179 (47%), Gaps = 18/179 (10%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
+E AA KQG LS + + S LHWA INNRL + L A
Sbjct: 36 VESVEAALKQG---------------LSPNTTDDDGCSLLHWAAINNRLEVARLLISYNA 80
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
+ N GG L ++P+HWA+++GLV + L+K GA N+ D QGY +H ++ +++ LV
Sbjct: 81 DANLIGGVLASSPIHWAARNGLVAMCAVLVKGGAVCNVRDIQGYTPIHLAIQGNHVPLVA 140
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADD-AGFTALH 251
Y L K+ D + A+ A + +++ AD+ + +G TALH
Sbjct: 141 YFLLKFEYAKDISD--NSGMTPAMMCAKRSFTMFPLRLIVRAGADLSLKEHFSGNTALH 197
>Hs10947056 [M] KOG4177 Ankyrin
Length = 4377
Score = 73.6 bits (179), Expect = 1e-12
Identities = 62/209 (29%), Positives = 91/209 (42%), Gaps = 14/209 (6%)
Query: 74 LERYHAACKQGDMKTLREMVESKV---IDLSNDYDPKERVSGLHWACINNRLSAVKYLAG 130
L H A G K + +++ K N + P LH AC NR+ ++ L
Sbjct: 368 LTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTP------LHIACKKNRIKVMELLLK 421
Query: 131 AGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIM 190
GA + E TP+H A+ G V IV +L+ GA PN T+ +G LH + S
Sbjct: 422 HGASIQAVT-ESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAE 480
Query: 191 LVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTAL 250
+V Y+ V DG + V+ +T L + A V+ LL+ A A +G+T L
Sbjct: 481 VVRYL---VQDGAQ-VEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPL 536
Query: 251 HWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
H +G V L+ HG+ TT G
Sbjct: 537 HLSAREGHEDVAAFLLDHGASLSITTKKG 565
Score = 58.9 bits (141), Expect = 3e-08
Identities = 51/177 (28%), Positives = 75/177 (41%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
D+ + ++ LH A + VK L GA+++ K + TPLH ++SG +V+ L
Sbjct: 262 DFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRD-GLTPLHCGARSGHEQVVEML 320
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
L A G + LH + ++ V +L V VD TAL A +
Sbjct: 321 LDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP----VDDVTNDYLTALHVAAH 376
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL A+ GFT LH K I VM+LL+KHG+ T G
Sbjct: 377 CGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESG 433
Score = 57.8 bits (138), Expect = 6e-08
Identities = 53/197 (26%), Positives = 81/197 (40%), Gaps = 6/197 (3%)
Query: 111 SGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPN 170
+ LH A + + V+YL GA+V K + D TPLH +++ G IV +LL+ GA PN
Sbjct: 468 TALHMAARSGQAEVVRYLVQDGAQVEAKAKD-DQTPLHISARLGKADIVQQLLQQGASPN 526
Query: 171 ITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVE 230
+ GY LH S + V F++D + T L A
Sbjct: 527 AATTSGYTPLHLSAREGH----EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVAN 582
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELY 290
LL+ +A A +G T LH + V LL+ G+ +G I +
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 642
Query: 291 SIGSLEASLYKNGFDKN 307
+ + +L + G D N
Sbjct: 643 QM-DIATTLLEYGADAN 658
Score = 56.6 bits (135), Expect = 1e-07
Identities = 52/204 (25%), Positives = 86/204 (41%), Gaps = 12/204 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACI--NNRLSAVKYLAGAGAEV 135
H A K G ++ +++ S D K ++ LH A N +++ + GA
Sbjct: 570 HVAAKYGKLEVANLLLQKSA---SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 626
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
K G TPLH A+K + I LL+ GAD N QG +H + ++ +V +
Sbjct: 627 AAKNGY---TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
L +V+ + T L A + E L+ A V G+T LH G
Sbjct: 684 L----GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCH 739
Query: 256 KGSIPVMDLLIKHGSDFFQTTNDG 279
G+I +++ L++H + T +G
Sbjct: 740 YGNIKIVNFLLQHSAKVNAKTKNG 763
Score = 52.0 bits (123), Expect = 3e-06
Identities = 48/188 (25%), Positives = 73/188 (38%), Gaps = 8/188 (4%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A K+ M ++E + ++ ++ +H A + V L G A VN
Sbjct: 636 HIAAKKNQMDIATTLLE---YGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNL 692
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
+ TPLH A++ V + + L+ GA + GY LH NI +V
Sbjct: 693 SN-KSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV----N 747
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
F++ V+ + T L A Q + LL+ NA G TAL G
Sbjct: 748 FLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLG 807
Query: 258 SIPVMDLL 265
I V+D L
Sbjct: 808 YISVVDTL 815
>Hs20538133 [R] KOG0504 FOG: Ankyrin repeat
Length = 899
Score = 72.0 bits (175), Expect = 3e-12
Identities = 48/158 (30%), Positives = 79/158 (49%), Gaps = 8/158 (5%)
Query: 125 VKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSV 184
VK L GA +N + D +HWA+ G + +V L+ GA+ D + Y LH +
Sbjct: 2 VKLLLSRGANIN-AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA 60
Query: 185 FSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADD 244
S I +V Y+L D D+++P+ + T L A Y + V L+ A V ++
Sbjct: 61 SSGMISVVKYLL----DLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNE 116
Query: 245 AGFTALHW--GTVKGSIPVMDLLIKHGSDFFQTTNDGK 280
GFT LH+ + G++ ++LL+ +G+D + DGK
Sbjct: 117 KGFTPLHFAAASTHGAL-CLELLVGNGADVNMKSKDGK 153
Score = 66.6 bits (161), Expect = 1e-10
Identities = 52/170 (30%), Positives = 79/170 (45%), Gaps = 7/170 (4%)
Query: 102 NDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDE 161
N +D K+R +HWA + VK L GAEV K + TPLH A+ SG++ +V
Sbjct: 13 NAFDKKDR-RAIHWAAYMGHIEVVKLLVSHGAEVTCK-DKKSYTPLHAAASSGMISVVKY 70
Query: 162 LLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWAT 221
LL G D N ++ G LH + ++ ++V ++D V+Q + T L +A
Sbjct: 71 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNE----LIDCGAIVNQKNEKGFTPLHFAA 126
Query: 222 YQA-DALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGS 270
AL +E L+ ADV G T LH + G +I+ G+
Sbjct: 127 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 176
Score = 62.0 bits (149), Expect = 3e-09
Identities = 54/204 (26%), Positives = 93/204 (45%), Gaps = 17/204 (8%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERV--SGLHWACINNRLSAVKYLAGAGAEV 135
HAA G+++ L + +++ D++ K++ S LH+A N + L G+GA V
Sbjct: 256 HAAAAGGNLECL-----NLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 310
Query: 136 NFKGGELDATPLHWASKSGLV-YIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIY 194
N E TPLH+A+ S ++ LL+ A+P I D QGYN +H S + + +
Sbjct: 311 NDLD-ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQL 369
Query: 195 V-------LFFVVDGKEDVDQPDPHQR-TALQWATYQADALTVENLLKFNADVKNADDAG 246
+ + G + + D + L A Y +E L++ D+ + +G
Sbjct: 370 IASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSG 429
Query: 247 FTALHWGTVKGSIPVMDLLIKHGS 270
T L KG + +D+LI G+
Sbjct: 430 RTPLDLAAFKGHVECVDVLINQGA 453
Score = 58.9 bits (141), Expect = 3e-08
Identities = 56/199 (28%), Positives = 85/199 (42%), Gaps = 4/199 (2%)
Query: 70 KDPILER--YHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKY 127
KD IL+R HAA G + LR ++ + + D + L + +N V
Sbjct: 458 KDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYS 517
Query: 128 LAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSS 187
L GA V+ K + T LH + +G VD LL+ GA + DS+G +H S
Sbjct: 518 LLNKGANVDAKD-KWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACG 576
Query: 188 NIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGF 247
+I ++ +L + D H TAL WA Y VE LL+ K +A F
Sbjct: 577 HIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNA-F 635
Query: 248 TALHWGTVKGSIPVMDLLI 266
+ LH + + ++LI
Sbjct: 636 SPLHCAVINDNEGAAEMLI 654
Score = 58.5 bits (140), Expect = 4e-08
Identities = 60/227 (26%), Positives = 95/227 (41%), Gaps = 9/227 (3%)
Query: 78 HAACKQ--GDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEV 135
H C Q L ++E+ D+ +D D + +S LH A + A++ L + ++
Sbjct: 363 HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDL 422
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
+ + TPL A+ G V VD L+ GA + D Y L T + ++
Sbjct: 423 DVRNSS-GRTPLDLAAFKGHVECVDVLINQGASILVKD---YILKRTPIHAAATNGHSEC 478
Query: 196 LFFVVDGKED---VDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHW 252
L ++ E VD D + +T L + V +LL A+V D G TALH
Sbjct: 479 LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHR 538
Query: 253 GTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASL 299
G V G +D L++HG+ + G+ + IG L A L
Sbjct: 539 GAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 585
Score = 57.8 bits (138), Expect = 6e-08
Identities = 48/206 (23%), Positives = 89/206 (42%), Gaps = 11/206 (5%)
Query: 78 HAACKQGDMKTLREMVE-SKVIDLSNDYDPKERVSGLHWACINNRLS-AVKYLAGAGAEV 135
H AC G + E+++ +++ N+ + + LH+A + + ++ L G GA+V
Sbjct: 90 HVACYNGQDVVVNELIDCGAIVNQKNE----KGFTPLHFAAASTHGALCLELLVGNGADV 145
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
N K + TPLH + G ++++GA + D G LH + + +L+ +
Sbjct: 146 NMKSKD-GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 204
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
+ D + H L A + LL D+ DD G T LH
Sbjct: 205 ----ITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAA 260
Query: 256 KGSIPVMDLLIKHGSDFFQTTNDGKN 281
G++ ++LL+ G+DF + G++
Sbjct: 261 GGNLECLNLLLNTGADFNKKDKFGRS 286
>Hs4502093 [M] KOG4177 Ankyrin
Length = 1088
Score = 71.6 bits (174), Expect = 4e-12
Identities = 54/167 (32%), Positives = 78/167 (46%), Gaps = 5/167 (2%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC NR+ ++ L GA + E TP+H A+ G V IV +L+ GA PN T
Sbjct: 25 LHIACKKNRIKVMELLLKHGASIQAVT-ESGLTPIHVAAFMGHVNIVSQLMHHGASPNTT 83
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+ +G LH + S +V Y+ V DG + V+ +T L + A V+ L
Sbjct: 84 NVRGETALHMAARSGQAEVVRYL---VQDGAQ-VEAKAKDDQTPLHISARLGKADIVQQL 139
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
L+ A A +G+T LH +G V L+ HG+ TT G
Sbjct: 140 LQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG 186
Score = 57.8 bits (138), Expect = 6e-08
Identities = 53/197 (26%), Positives = 81/197 (40%), Gaps = 6/197 (3%)
Query: 111 SGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPN 170
+ LH A + + V+YL GA+V K + D TPLH +++ G IV +LL+ GA PN
Sbjct: 89 TALHMAARSGQAEVVRYLVQDGAQVEAKAKD-DQTPLHISARLGKADIVQQLLQQGASPN 147
Query: 171 ITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVE 230
+ GY LH S + V F++D + T L A
Sbjct: 148 AATTSGYTPLHLSAREGH----EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVAN 203
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELY 290
LL+ +A A +G T LH + V LL+ G+ +G I +
Sbjct: 204 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 263
Query: 291 SIGSLEASLYKNGFDKN 307
+ + +L + G D N
Sbjct: 264 QM-DIATTLLEYGADAN 279
Score = 56.6 bits (135), Expect = 1e-07
Identities = 52/204 (25%), Positives = 86/204 (41%), Gaps = 12/204 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACI--NNRLSAVKYLAGAGAEV 135
H A K G ++ +++ S D K ++ LH A N +++ + GA
Sbjct: 191 HVAAKYGKLEVANLLLQKSA---SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 247
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
K G TPLH A+K + I LL+ GAD N QG +H + ++ +V +
Sbjct: 248 AAKNGY---TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 304
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
L +V+ + T L A + E L+ A V G+T LH G
Sbjct: 305 L----GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCH 360
Query: 256 KGSIPVMDLLIKHGSDFFQTTNDG 279
G+I +++ L++H + T +G
Sbjct: 361 YGNIKIVNFLLQHSAKVNAKTKNG 384
Score = 52.0 bits (123), Expect = 3e-06
Identities = 48/188 (25%), Positives = 73/188 (38%), Gaps = 8/188 (4%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A K+ M ++E + ++ ++ +H A + V L G A VN
Sbjct: 257 HIAAKKNQMDIATTLLE---YGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNL 313
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
+ TPLH A++ V + + L+ GA + GY LH NI +V
Sbjct: 314 SN-KSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV----N 368
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
F++ V+ + T L A Q + LL+ NA G TAL G
Sbjct: 369 FLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLG 428
Query: 258 SIPVMDLL 265
I V+D L
Sbjct: 429 YISVVDTL 436
>7298956 [R] KOG0510 Ankyrin repeat protein
Length = 914
Score = 71.6 bits (174), Expect = 4e-12
Identities = 50/166 (30%), Positives = 83/166 (49%), Gaps = 5/166 (3%)
Query: 122 LSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLH 181
L A+ A A V E ++T LH A+ G V VD LL GAD + + +G+ LH
Sbjct: 228 LEALLNAPNADANVRICIREKESTALHLAADEGNVECVDLLLAKGADAKLKNHRGFTPLH 287
Query: 182 TSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADAL--TVENLLKFNADV 239
+ +S++ V +L +G D + D RT L A +++ +E L+++ A+V
Sbjct: 288 LAARTSSLDCVESLLR---NGNADANAEDFDHRTPLHAAVGKSENAYDIMETLIQWGANV 344
Query: 240 KNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTI 285
+ D GFTALH + G + +++LI HG+D + G + +
Sbjct: 345 NHKDIYGFTALHLAALDGLVQCVEMLIFHGADVTTKSKKGTSALNV 390
>Hs14731279 [R] KOG0504 FOG: Ankyrin repeat
Length = 743
Score = 70.9 bits (172), Expect = 7e-12
Identities = 58/188 (30%), Positives = 88/188 (45%), Gaps = 6/188 (3%)
Query: 123 SAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHT 182
S V L GAEV+ + TPL A+ G V +VD LL+ GAD + TD+ G L
Sbjct: 43 SVVSLLIDRGAEVDHCDKD-GMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLA 101
Query: 183 SVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNA 242
+ + +V +LF+ VD D RT L A+ Q + V LL D +
Sbjct: 102 AASMGHASVVNTLLFWGAA----VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHR 157
Query: 243 DDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASL-YK 301
DDAG+T LH +G + + LI+ G+ + NDG+ F + + ++ L K
Sbjct: 158 DDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENK 217
Query: 302 NGFDKNGF 309
+ D+ G+
Sbjct: 218 SNIDQRGY 225
Score = 61.6 bits (148), Expect = 4e-09
Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 5/161 (3%)
Query: 147 LHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDV 206
L A+ G IV+ L GAD N D+ G L+ + + + Y L + +V
Sbjct: 231 LRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL----ENGANV 286
Query: 207 DQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLI 266
+ D RTAL + +Q V+ L+ ++ADV AD+ +AL +G + V+ LLI
Sbjct: 287 EASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLI 346
Query: 267 KHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKNGFDKN 307
+HG+ T N G I + I ++ L ++G D N
Sbjct: 347 EHGAVVDHTCNQGATALCIAAQEGHIDVVQV-LLEHGADPN 386
>7304338 [M] KOG4177 Ankyrin
Length = 1526
Score = 70.9 bits (172), Expect = 7e-12
Identities = 58/202 (28%), Positives = 89/202 (43%), Gaps = 8/202 (3%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A G++ ++ +K +Y K ++ LH AC +LS L GA+++
Sbjct: 216 HIAAHYGNVDIATLLLNNKA---DVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDA 272
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
+ TPLH AS+SG V ++ LL+ A G + LH + + +L
Sbjct: 273 ATRD-GLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLL- 330
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
D K VD+ TAL A + + LL + A+ GFT LH K
Sbjct: 331 ---DNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKN 387
Query: 258 SIPVMDLLIKHGSDFFQTTNDG 279
I +++LLIKHG++ TT G
Sbjct: 388 RIKMVELLIKHGANIGATTESG 409
Score = 68.2 bits (165), Expect = 5e-11
Identities = 53/202 (26%), Positives = 95/202 (46%), Gaps = 9/202 (4%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A K+G ++ ++E+ N+ K+ + LH AC + + V+ L GA ++F
Sbjct: 512 HIAAKEGQENIVQVLLENGA---ENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDF 568
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
+G D TPLH A+ IV+ LLK G+ PN+ G +H + + + + + +L
Sbjct: 569 QGKN-DVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLL- 626
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
DV+ + L A + V+ LL++ + A G T LH +G
Sbjct: 627 ---QHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEG 682
Query: 258 SIPVMDLLIKHGSDFFQTTNDG 279
+ V +L++HG++ + T +G
Sbjct: 683 HVLVSQILLEHGANISERTRNG 704
Score = 67.8 bits (164), Expect = 6e-11
Identities = 57/250 (22%), Positives = 108/250 (42%), Gaps = 36/250 (14%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H ACK G ++ ++++ S D+ K V+ LH A N S V+ L G+ N
Sbjct: 545 HLACKYGKQNVVQILLQNGA---SIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNL 601
Query: 138 --KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
+ G+ +H A K + I +LL+ GAD NI G++ LH + N+ +V +
Sbjct: 602 CARNGQC---AIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLL 658
Query: 196 LFF----------------------------VVDGKEDVDQPDPHQRTALQWATYQADAL 227
L + +++ ++ + + T L A +
Sbjct: 659 LEYGVISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLD 718
Query: 228 TVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGK 287
V+ ++ +AD++ + + G+T LH +G I +++LL++H ++ T DG I
Sbjct: 719 LVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIAS 778
Query: 288 ELYSIGSLEA 297
L + +E+
Sbjct: 779 NLGYVTVMES 788
Score = 62.4 bits (150), Expect = 2e-09
Identities = 61/216 (28%), Positives = 92/216 (42%), Gaps = 11/216 (5%)
Query: 110 VSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADP 169
++ LH A + K L A N + TPLH A K + +V+ L+K GA+
Sbjct: 344 LTALHVAAHCGHVKVAKLLLDYKANPNARALN-GFTPLHIACKKNRIKMVELLIKHGANI 402
Query: 170 NITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTV 229
T G LH + F I +VIY+L + D P T L A +A+ +
Sbjct: 403 GATTESGLTPLHVASFMGCINIVIYLL----QHEASADLPTIRGETPLHLAA-RANQADI 457
Query: 230 ENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTI---- 285
+L +A V G T LH + G+I ++ LL++HG++ +ND + I
Sbjct: 458 IRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKE 517
Query: 286 GKELYSIGSLEASLYKNGFDKNGFPLPQYFSASTGK 321
G+E LE N K GF P + + GK
Sbjct: 518 GQENIVQVLLENGAENNAVTKKGF-TPLHLACKYGK 552
Score = 52.4 bits (124), Expect = 3e-06
Identities = 48/188 (25%), Positives = 79/188 (41%), Gaps = 9/188 (4%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H ACK+ ++ ++++ + K S LH A + V+ L G V
Sbjct: 611 HIACKKNYLEIAMQLLQHGA---DVNIISKSGFSPLHLAAQGGNVDMVQLLLEYG--VIS 665
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
+ TPLH A++ G V + LL+ GA+ + GY LH + ++ LV
Sbjct: 666 AAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVK---- 721
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
F ++ D++ T L A Q + + LL+ A+ G TALH + G
Sbjct: 722 FFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLG 781
Query: 258 SIPVMDLL 265
+ VM+ L
Sbjct: 782 YVTVMESL 789
>Hs13376842 [M] KOG4177 Ankyrin
Length = 1166
Score = 70.5 bits (171), Expect = 9e-12
Identities = 62/222 (27%), Positives = 95/222 (41%), Gaps = 28/222 (12%)
Query: 71 DPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSG-LHWACINNRLSAVKYLA 129
+P AC+ GD++ ++ +V + + N D R S LH+A R V+YL
Sbjct: 22 EPAARELFEACRNGDVERVKRLVTPEKV---NSRDTAGRKSTPLHFAAGFGRKDVVEYLL 78
Query: 130 GAGAEVNFK--GGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSS 187
GA V + GG + PLH A G +V+ LL+ GADPN D+ Y LH +
Sbjct: 79 QNGANVQARDDGGLI---PLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKG 135
Query: 188 NIMLVIYVL-------FFVVDGKEDVDQPDPHQRTALQWATYQADAL-----------TV 229
I + I +L DG+ +D DP + L Y+ D L +
Sbjct: 136 KIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLT-GEYKKDELLESARSGNEEKMM 194
Query: 230 ENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
L N + +D T LH + ++ LL++HG+D
Sbjct: 195 ALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 236
>7295202 [M] KOG4177 Ankyrin
Length = 2443
Score = 70.1 bits (170), Expect = 1e-11
Identities = 52/177 (29%), Positives = 78/177 (43%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
+Y K +S LH A + + V L G + K + TPLH A++SG +VD L
Sbjct: 232 NYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRD-GLTPLHCAARSGHEQVVDML 290
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
L+ GA + G LH + ++ +L+ + VD+ TAL A +
Sbjct: 291 LERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYH----RAPVDEVTVDYLTALHVAAH 346
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL NAD GFT LH K + V++LL++HG+ TT G
Sbjct: 347 CGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESG 403
Score = 58.5 bits (140), Expect = 4e-08
Identities = 49/169 (28%), Positives = 73/169 (42%), Gaps = 5/169 (2%)
Query: 110 VSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADP 169
++ LH A + K L A+ N + TPLH A K + +V+ LL+ GA
Sbjct: 338 LTALHVAAHCGHVRVAKLLLDRNADANARALN-GFTPLHIACKKNRLKVVELLLRHGASI 396
Query: 170 NITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTV 229
+ T G LH + F + +VIY+L D DV P T L A +
Sbjct: 397 SATTESGLTPLHVAAFMGCMNIVIYLLQH--DASPDV--PTVRGETPLHLAARANQTDII 452
Query: 230 ENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTND 278
LL+ A V T LH + G++ ++ LL++HG+ TT D
Sbjct: 453 RILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKD 501
Score = 55.1 bits (131), Expect = 4e-07
Identities = 62/251 (24%), Positives = 102/251 (39%), Gaps = 37/251 (14%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWAC-INNRLSAVKYLA-GAGAEV 135
H K G +K + +++ + D K V+ LH AC NN+ A+ L GA
Sbjct: 555 HLTAKYGHIKVAQLLLQKEA---DVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHA 611
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFS-----SNIM 190
K G TPLH A++ + I LL+ GA N G+ LH S SN++
Sbjct: 612 TAKNGH---TPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLL 668
Query: 191 LV------------------------IYVLFFVVDGKEDVDQPDPHQRTALQWATYQADA 226
+ + V + ++D T L A++ A
Sbjct: 669 IEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQA 728
Query: 227 LTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIG 286
V LL+ A+V A G+T LH +G +++LL++H ++ T +G+ I
Sbjct: 729 NMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIA 788
Query: 287 KELYSIGSLEA 297
++L I L++
Sbjct: 789 RKLGYISVLDS 799
>Hs7657238 [R] KOG0504 FOG: Ankyrin repeat
Length = 1065
Score = 69.7 bits (169), Expect = 2e-11
Identities = 64/218 (29%), Positives = 98/218 (44%), Gaps = 13/218 (5%)
Query: 67 SVEKDPILE---RYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLS 123
SV+ D LE + A +G LR M+ K D+ + K + LH A ++ +S
Sbjct: 313 SVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS-DIDINMADKYGGTALHAAALSGHVS 371
Query: 124 AVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTS 183
VK L A+V+ + TPL A + G ++ L+K GA ++ D G++LLH +
Sbjct: 372 TVKLLLENNAQVDATD-VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWA 430
Query: 184 VFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNAD 243
N V +++ K + + D RT LQ A Y + L++ NAD D
Sbjct: 431 ALGGNAD----VCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQD 486
Query: 244 DAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKN 281
G TALHW G + + LL+ DF N +N
Sbjct: 487 KEGRTALHWSCNNGYLDAIKLLL----DFAAFPNQMEN 520
Score = 57.8 bits (138), Expect = 6e-08
Identities = 50/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 111 SGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPN 170
S +H A +N A++ L + + K + TPL + + + D LLKAGAD N
Sbjct: 16 SQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVN 75
Query: 171 ITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVE 230
TD LH + N + +L + + Q D + T L T +
Sbjct: 76 KTDHSQRTALHLAAQKGNYRFMKLLL----TRRANWMQKDLEEMTPLHLTTRHRSPKCLA 131
Query: 231 NLLKFNA--DVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGK 280
LLKF A +V D TALHW + + LLIKH S+ +GK
Sbjct: 132 LLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGK 183
Score = 57.0 bits (136), Expect = 1e-07
Identities = 47/180 (26%), Positives = 81/180 (44%), Gaps = 5/180 (2%)
Query: 73 ILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAG 132
+ + HAA GD L+ ++ D + + + L + + +RL L AG
Sbjct: 14 LASQVHAAAVNGDKGALQRLIVGN--SALKDKEDQFGRTPLMYCVLADRLDCADALLKAG 71
Query: 133 AEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLV 192
A+VN K T LH A++ G + LL A+ D + LH + + +
Sbjct: 72 ADVN-KTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCL 130
Query: 193 IYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHW 252
+L F+ G +VD D +++TAL W+ Y + V+ L+K ++++ D G LHW
Sbjct: 131 ALLLKFMAPG--EVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHW 188
>Hs4507613 [M] KOG4177 Ankyrin
Length = 1327
Score = 68.2 bits (165), Expect = 5e-11
Identities = 59/212 (27%), Positives = 92/212 (42%), Gaps = 26/212 (12%)
Query: 80 ACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFK- 138
AC+ GD+ ++ +V++ ++ + K S LH+A R V++L GA V+ +
Sbjct: 189 ACRNGDVSRVKRLVDAANVNAKDMAGRKS--SPLHFAAGFGRKDVVEHLLQMGANVHARD 246
Query: 139 -GGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVL- 196
GG + PLH A G +V LL GADPN D+ Y LH + I + I +L
Sbjct: 247 DGGLI---PLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 303
Query: 197 ------FFVVDGKEDVDQPDPHQRTALQWATYQADAL-----------TVENLLKFNADV 239
DGK +D DP + L Y+ D L + L N +
Sbjct: 304 HGADPNIRNTDGKSALDLADPSAKAVLT-GEYKKDELLEAARSGNEEKLMALLTPLNVNC 362
Query: 240 KNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
+D T LH + ++ LL++HG+D
Sbjct: 363 HASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD 394
>CE07175 [R] KOG0508 Ankyrin repeat protein
Length = 656
Score = 68.2 bits (165), Expect = 5e-11
Identities = 53/163 (32%), Positives = 77/163 (46%), Gaps = 12/163 (7%)
Query: 116 ACINNRLSAVKYLAGAGAE------VNFKGGELDATPLHWA-SKSGLVYIVDELL-KAGA 167
A N + V+YL GA+ V F + TP WA S +G + IV L+ KA A
Sbjct: 55 AARNGHANVVEYLLEIGADPSVRGVVEFDNENIQGTPPLWAASAAGHIEIVKLLIEKANA 114
Query: 168 DPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADAL 227
D N + L + + ++ +V Y+L + D P+ H T L A+Y+
Sbjct: 115 DVNQATNTRSTPLRGACYDGHLDIVKYLL----EKGADPHIPNRHGHTCLMIASYRNKVG 170
Query: 228 TVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGS 270
VE LLK DV + G TALH G++ V+ +L+KHGS
Sbjct: 171 IVEELLKTGIDVNKKTERGNTALHDAAESGNVEVVKILLKHGS 213
>Hs4506217 [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 226
Score = 67.8 bits (164), Expect = 6e-11
Identities = 54/203 (26%), Positives = 86/203 (41%), Gaps = 12/203 (5%)
Query: 89 LREMVESKVIDLS----NDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDA 144
L E+ ES + D S D D + + LHWAC V++L G VN K +
Sbjct: 19 LEELKESILADKSLATRTDQDSR---TALHWACSAGHTEIVEFLLQLGVPVNDKD-DAGW 74
Query: 145 TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE 204
+PLH A+ +G IV LL GA N + G LH + + + + +L +G
Sbjct: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL----EGGA 130
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
+ D D ++ TA+ A + + + LL + A D G T LH + + L
Sbjct: 131 NPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
Query: 265 LIKHGSDFFQTTNDGKNCFTIGK 287
L+ G+ + + K + K
Sbjct: 191 LVSQGASIYIENKEEKTPLQVAK 213
>7297920 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 585
Score = 66.6 bits (161), Expect = 1e-10
Identities = 45/186 (24%), Positives = 83/186 (44%), Gaps = 8/186 (4%)
Query: 82 KQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKG-G 140
K G++ + +V+ ++ + D + + HW +N + ++YL A ++ G
Sbjct: 95 KNGEVSEVENLVDKFGMECLSARD-RHGYTPAHWIALNGNVQLMRYLIERTAPIDLPCLG 153
Query: 141 ELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVL-FFV 199
P+HWA + G +V LL+AG N D +G LH + Y+L
Sbjct: 154 TQGPRPIHWACRKGHASVVQVLLQAGVAVNAADFKGLTPLHLACMYGRTATAAYLLGMGA 213
Query: 200 VDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSI 259
++ D++ TAL WA Y+ A + L+ +++ D+ G T LH + G++
Sbjct: 214 LNNLTDINGD-----TALHWAAYKGHADLMRLLMYSGVELQKTDNFGSTPLHLACLSGNM 268
Query: 260 PVMDLL 265
+ LL
Sbjct: 269 TCVRLL 274
Score = 53.5 bits (127), Expect = 1e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Query: 434 KSDPGYIPGTVDHDKVRETIKELLSLGKFDAKH-----FCVHTWIRIPLRSKYDRDSACL 488
+ DPGYIP + D IK++ K ++ C PLR+K+ R
Sbjct: 390 RRDPGYIP--LSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRC 447
Query: 489 ISAFDHFCPWVYNQIGLLNHKLFYMFVVLLEIS 521
+S FDH CP++YN +GL N F++FV+ + ++
Sbjct: 448 VSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVN 480
>7299952 [R] KOG0508 Ankyrin repeat protein
Length = 662
Score = 65.5 bits (158), Expect = 3e-10
Identities = 52/163 (31%), Positives = 75/163 (45%), Gaps = 12/163 (7%)
Query: 116 ACINNRLSAVKYL---AGAGAE----VNFKGGEL-DATPLHWASKSGLVYIVDELLKAGA 167
+C N V+YL A E V+F G + DA PL A+ +G + IV L++ GA
Sbjct: 46 SCRNGHYDIVEYLLTKCRANVEQVGSVSFDGEPIEDAPPLWCAAAAGHLGIVKMLVRRGA 105
Query: 168 DPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADAL 227
+ N T L + F + +V Y+ V D + + H T L A Y+
Sbjct: 106 NVNSTTRTNSTPLRAACFDGHYEIVKYL----VHHGADFEVANRHGHTCLMIACYKGHFR 161
Query: 228 TVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGS 270
+ LL NADV G TALH GS+ ++ LL+KHG+
Sbjct: 162 IAQYLLSLNADVNRCSVKGNTALHDCAESGSLQILQLLLKHGA 204
>Hs10947054 [M] KOG4177 Ankyrin
Length = 1872
Score = 63.9 bits (154), Expect = 9e-10
Identities = 53/186 (28%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 107 KERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAG 166
K + LH A N++ L GAE N + TPLH AS+ G +V LL G
Sbjct: 627 KNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQ-GVTPLHLASQEGHTDMVTLLLDKG 685
Query: 167 ADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR---TALQWATYQ 223
A+ +++ G LH + + + + K DQ D H + T L A +
Sbjct: 686 ANIHMSTKSGLTSLHLAAQEDKVNVADILT------KHGADQ-DAHTKLGYTPLIVACHY 738
Query: 224 ADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCF 283
+ V LLK A+V G+T LH +G ++++L++HG+ TT +G
Sbjct: 739 GNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTAL 798
Query: 284 TIGKEL 289
I K L
Sbjct: 799 AIAKRL 804
Score = 62.8 bits (151), Expect = 2e-09
Identities = 51/177 (28%), Positives = 78/177 (43%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
D+ + ++ LH A + VK L G +++ K + TPLH A++SG +V+ L
Sbjct: 260 DFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD-GLTPLHCAARSGHDQVVELL 318
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
L+ GA G + LH + ++ V ++L K VD TAL A +
Sbjct: 319 LERGAPLLARTKNGLSPLHMAAQGDHVECVKHLL----QHKAPVDDVTLDYLTALHVAAH 374
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL A+ GFT LH K I VM+LL+K+G+ T G
Sbjct: 375 CGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESG 431
Score = 58.5 bits (140), Expect = 4e-08
Identities = 48/167 (28%), Positives = 77/167 (45%), Gaps = 5/167 (2%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC NR+ ++ L GA + E TP+H A+ G + IV LL+ GA P++T
Sbjct: 402 LHIACKKNRIKVMELLVKYGASIQAIT-ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT 460
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+ +G LH + + + +V +L VD ++T L A+ V+ L
Sbjct: 461 NIRGETALHMAARAGQVEVVRCLL----RNGALVDARAREEQTPLHIASRLGKTEIVQLL 516
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
L+ A A G+T LH +G + V +L++ G+ T G
Sbjct: 517 LQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKG 563
Score = 54.7 bits (130), Expect = 5e-07
Identities = 54/212 (25%), Positives = 95/212 (44%), Gaps = 16/212 (7%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
L H A K+G + ++E++ S D K+ + LH A + + VK L GA
Sbjct: 65 LNALHLAAKEGHVGLVQELLGR---GSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA 121
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
+N + + TPL+ A++ + +V LL+ GA+ + G+ L ++ + V
Sbjct: 122 NINAQS-QNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVA 180
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKN------ADDAGF 247
+L GK + P A + ++ AL ++N NADV++ ++GF
Sbjct: 181 ILLENDTKGKVRL----PALHIAARKDDTKSAALLLQN--DHNADVQSKMMVNRTTESGF 234
Query: 248 TALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
T LH G++ V LL+ G+ T +G
Sbjct: 235 TPLHIAAHYGNVNVATLLLNRGAAVDFTARNG 266
Score = 52.0 bits (123), Expect = 3e-06
Identities = 39/131 (29%), Positives = 62/131 (46%), Gaps = 6/131 (4%)
Query: 150 ASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGK-EDVDQ 208
A+++G + V E LK G D N + G N LH + ++ LV +L G+ VD
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELL-----GRGSSVDS 92
Query: 209 PDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKH 268
TAL A+ A V+ L+K A++ GFT L+ + I V+ L+++
Sbjct: 93 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLEN 152
Query: 269 GSDFFQTTNDG 279
G++ T DG
Sbjct: 153 GANQSTATEDG 163
>Hs10947052 [M] KOG4177 Ankyrin
Length = 3957
Score = 63.9 bits (154), Expect = 9e-10
Identities = 53/186 (28%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 107 KERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAG 166
K + LH A N++ L GAE N + TPLH AS+ G +V LL G
Sbjct: 627 KNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQ-GVTPLHLASQEGHTDMVTLLLDKG 685
Query: 167 ADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR---TALQWATYQ 223
A+ +++ G LH + + + + K DQ D H + T L A +
Sbjct: 686 ANIHMSTKSGLTSLHLAAQEDKVNVADILT------KHGADQ-DAHTKLGYTPLIVACHY 738
Query: 224 ADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCF 283
+ V LLK A+V G+T LH +G ++++L++HG+ TT +G
Sbjct: 739 GNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTAL 798
Query: 284 TIGKEL 289
I K L
Sbjct: 799 AIAKRL 804
Score = 62.8 bits (151), Expect = 2e-09
Identities = 51/177 (28%), Positives = 78/177 (43%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
D+ + ++ LH A + VK L G +++ K + TPLH A++SG +V+ L
Sbjct: 260 DFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD-GLTPLHCAARSGHDQVVELL 318
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
L+ GA G + LH + ++ V ++L K VD TAL A +
Sbjct: 319 LERGAPLLARTKNGLSPLHMAAQGDHVECVKHLL----QHKAPVDDVTLDYLTALHVAAH 374
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL A+ GFT LH K I VM+LL+K+G+ T G
Sbjct: 375 CGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESG 431
Score = 58.5 bits (140), Expect = 4e-08
Identities = 48/167 (28%), Positives = 77/167 (45%), Gaps = 5/167 (2%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC NR+ ++ L GA + E TP+H A+ G + IV LL+ GA P++T
Sbjct: 402 LHIACKKNRIKVMELLVKYGASIQAIT-ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT 460
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+ +G LH + + + +V +L VD ++T L A+ V+ L
Sbjct: 461 NIRGETALHMAARAGQVEVVRCLL----RNGALVDARAREEQTPLHIASRLGKTEIVQLL 516
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
L+ A A G+T LH +G + V +L++ G+ T G
Sbjct: 517 LQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKG 563
Score = 54.7 bits (130), Expect = 5e-07
Identities = 54/212 (25%), Positives = 95/212 (44%), Gaps = 16/212 (7%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
L H A K+G + ++E++ S D K+ + LH A + + VK L GA
Sbjct: 65 LNALHLAAKEGHVGLVQELLGR---GSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA 121
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
+N + + TPL+ A++ + +V LL+ GA+ + G+ L ++ + V
Sbjct: 122 NINAQS-QNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVA 180
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKN------ADDAGF 247
+L GK + P A + ++ AL ++N NADV++ ++GF
Sbjct: 181 ILLENDTKGKVRL----PALHIAARKDDTKSAALLLQN--DHNADVQSKMMVNRTTESGF 234
Query: 248 TALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
T LH G++ V LL+ G+ T +G
Sbjct: 235 TPLHIAAHYGNVNVATLLLNRGAAVDFTARNG 266
Score = 52.0 bits (123), Expect = 3e-06
Identities = 39/131 (29%), Positives = 62/131 (46%), Gaps = 6/131 (4%)
Query: 150 ASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGK-EDVDQ 208
A+++G + V E LK G D N + G N LH + ++ LV +L G+ VD
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELL-----GRGSSVDS 92
Query: 209 PDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKH 268
TAL A+ A V+ L+K A++ GFT L+ + I V+ L+++
Sbjct: 93 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLEN 152
Query: 269 GSDFFQTTNDG 279
G++ T DG
Sbjct: 153 GANQSTATEDG 163
>7294194 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 1023
Score = 63.9 bits (154), Expect = 9e-10
Identities = 61/239 (25%), Positives = 110/239 (45%), Gaps = 30/239 (12%)
Query: 47 SRASSELKHENDQGEERDLGSVEKDPILERYHAACKQGDMKTLREMVESKV-IDLSNDYD 105
+RA+ +HE+ + + G V + AAC GD + ++++ I+ +N
Sbjct: 28 NRAAPTPRHEHGRRIKFSSGCV--------FLAACLSGDKDEVVQLLDQGADINTAN--- 76
Query: 106 PKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKA 165
+ ++ LH ACI++ L V++L GA++N + E TPLH + G V I L++
Sbjct: 77 -VDGLTALHQACIDDNLDMVEFLVERGADINRQDNE-GWTPLHATASCGFVSIARYLVEN 134
Query: 166 GADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTAL-----QWA 220
GAD +S G L ++ ++ ++ Y+ V + +VD+ + A+ +W
Sbjct: 135 GADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKW- 193
Query: 221 TYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
++DA V+ + G TALH KG V+ LL+ + + NDG
Sbjct: 194 -LRSDAAEVD---------RPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDG 242
>CE06705 [M] KOG4177 Ankyrin
Length = 1815
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACI--NNRLSAVKYLAGAGAEV 135
H A K G+++ +R ++E D + K +V+ LH A N++++ + GA A+
Sbjct: 562 HLASKYGNLEVVRLLLERGT---PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
K G TPLH A+K + I LL+ ADPN G+ LH S + +
Sbjct: 619 AAKNGY---TPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKE----I 671
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
+++ DV + TA+ + + L A++ + +AG+T LH
Sbjct: 672 SGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACH 731
Query: 256 KGSIPVMDLLIKHGSDFFQTT 276
G + ++ L+++G+D + T
Sbjct: 732 FGQLNMVKFLVENGADVGEKT 752
Score = 58.2 bits (139), Expect = 5e-08
Identities = 49/177 (27%), Positives = 77/177 (42%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
+Y + +S LH A R + L GA ++ + +L TPLH A++SG +VD L
Sbjct: 254 NYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDL-LTPLHCAARSGHDQVVDLL 312
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
+ GA + G LH + ++ +L+ + VD T L A +
Sbjct: 313 VVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYH----RAPVDDVTVDYLTPLHVAAH 368
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL +AD + GFT LH K I V++LL+K+ + TT G
Sbjct: 369 CGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESG 425
Score = 53.9 bits (128), Expect = 9e-07
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 5/163 (3%)
Query: 145 TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE 204
TPLH ASK G + +V LL+ G +I LH + +N + + +L +
Sbjct: 559 TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLL----ENGA 614
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
+ T L A + LL+F AD AGFT LH +G + L
Sbjct: 615 SAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGL 674
Query: 265 LIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKNGFDKN 307
LI++GSD N+G + + + + LY NG + N
Sbjct: 675 LIENGSDVGAKANNGLTAMHLCAQEDHV-PVAQILYNNGAEIN 716
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 150 ASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQP 209
A+++G + V ELL+AG D N +++ G N LH + + +V + + + VD
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVREL----IKRQAQVDAA 95
Query: 210 DPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
TAL A+ +L V L++ A+V GFT L+ + V+ L+KHG
Sbjct: 96 TRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 270 SDFFQTTNDG 279
++ +T DG
Sbjct: 156 ANQALSTEDG 165
>CE06704 [M] KOG4177 Ankyrin
Length = 1867
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACI--NNRLSAVKYLAGAGAEV 135
H A K G+++ +R ++E D + K +V+ LH A N++++ + GA A+
Sbjct: 562 HLASKYGNLEVVRLLLERGT---PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
K G TPLH A+K + I LL+ ADPN G+ LH S + +
Sbjct: 619 AAKNGY---TPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKE----I 671
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
+++ DV + TA+ + + L A++ + +AG+T LH
Sbjct: 672 SGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACH 731
Query: 256 KGSIPVMDLLIKHGSDFFQTT 276
G + ++ L+++G+D + T
Sbjct: 732 FGQLNMVKFLVENGADVGEKT 752
Score = 58.2 bits (139), Expect = 5e-08
Identities = 49/177 (27%), Positives = 77/177 (42%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
+Y + +S LH A R + L GA ++ + +L TPLH A++SG +VD L
Sbjct: 254 NYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDL-LTPLHCAARSGHDQVVDLL 312
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
+ GA + G LH + ++ +L+ + VD T L A +
Sbjct: 313 VVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYH----RAPVDDVTVDYLTPLHVAAH 368
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL +AD + GFT LH K I V++LL+K+ + TT G
Sbjct: 369 CGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESG 425
Score = 53.9 bits (128), Expect = 9e-07
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 5/163 (3%)
Query: 145 TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE 204
TPLH ASK G + +V LL+ G +I LH + +N + + +L +
Sbjct: 559 TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLL----ENGA 614
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
+ T L A + LL+F AD AGFT LH +G + L
Sbjct: 615 SAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGL 674
Query: 265 LIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKNGFDKN 307
LI++GSD N+G + + + + LY NG + N
Sbjct: 675 LIENGSDVGAKANNGLTAMHLCAQEDHV-PVAQILYNNGAEIN 716
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 150 ASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQP 209
A+++G + V ELL+AG D N +++ G N LH + + +V + + + VD
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVREL----IKRQAQVDAA 95
Query: 210 DPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
TAL A+ +L V L++ A+V GFT L+ + V+ L+KHG
Sbjct: 96 TRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 270 SDFFQTTNDG 279
++ +T DG
Sbjct: 156 ANQALSTEDG 165
>CE06703 [M] KOG4177 Ankyrin
Length = 1809
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACI--NNRLSAVKYLAGAGAEV 135
H A K G+++ +R ++E D + K +V+ LH A N++++ + GA A+
Sbjct: 562 HLASKYGNLEVVRLLLERGT---PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
K G TPLH A+K + I LL+ ADPN G+ LH S + +
Sbjct: 619 AAKNGY---TPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKE----I 671
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
+++ DV + TA+ + + L A++ + +AG+T LH
Sbjct: 672 SGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACH 731
Query: 256 KGSIPVMDLLIKHGSDFFQTT 276
G + ++ L+++G+D + T
Sbjct: 732 FGQLNMVKFLVENGADVGEKT 752
Score = 58.2 bits (139), Expect = 5e-08
Identities = 49/177 (27%), Positives = 77/177 (42%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
+Y + +S LH A R + L GA ++ + +L TPLH A++SG +VD L
Sbjct: 254 NYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDL-LTPLHCAARSGHDQVVDLL 312
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
+ GA + G LH + ++ +L+ + VD T L A +
Sbjct: 313 VVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYH----RAPVDDVTVDYLTPLHVAAH 368
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL +AD + GFT LH K I V++LL+K+ + TT G
Sbjct: 369 CGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESG 425
Score = 53.9 bits (128), Expect = 9e-07
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 5/163 (3%)
Query: 145 TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE 204
TPLH ASK G + +V LL+ G +I LH + +N + + +L +
Sbjct: 559 TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLL----ENGA 614
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
+ T L A + LL+F AD AGFT LH +G + L
Sbjct: 615 SAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGL 674
Query: 265 LIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKNGFDKN 307
LI++GSD N+G + + + + LY NG + N
Sbjct: 675 LIENGSDVGAKANNGLTAMHLCAQEDHV-PVAQILYNNGAEIN 716
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 150 ASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQP 209
A+++G + V ELL+AG D N +++ G N LH + + +V + + + VD
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVREL----IKRQAQVDAA 95
Query: 210 DPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
TAL A+ +L V L++ A+V GFT L+ + V+ L+KHG
Sbjct: 96 TRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 270 SDFFQTTNDG 279
++ +T DG
Sbjct: 156 ANQALSTEDG 165
>CE06702 [M] KOG4177 Ankyrin
Length = 2039
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACI--NNRLSAVKYLAGAGAEV 135
H A K G+++ +R ++E D + K +V+ LH A N++++ + GA A+
Sbjct: 562 HLASKYGNLEVVRLLLERGT---PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKA 618
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
K G TPLH A+K + I LL+ ADPN G+ LH S + +
Sbjct: 619 AAKNGY---TPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKE----I 671
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
+++ DV + TA+ + + L A++ + +AG+T LH
Sbjct: 672 SGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACH 731
Query: 256 KGSIPVMDLLIKHGSDFFQTT 276
G + ++ L+++G+D + T
Sbjct: 732 FGQLNMVKFLVENGADVGEKT 752
Score = 58.2 bits (139), Expect = 5e-08
Identities = 49/177 (27%), Positives = 77/177 (42%), Gaps = 5/177 (2%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDEL 162
+Y + +S LH A R + L GA ++ + +L TPLH A++SG +VD L
Sbjct: 254 NYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDL-LTPLHCAARSGHDQVVDLL 312
Query: 163 LKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATY 222
+ GA + G LH + ++ +L+ + VD T L A +
Sbjct: 313 VVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYH----RAPVDDVTVDYLTPLHVAAH 368
Query: 223 QADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
+ LL +AD + GFT LH K I V++LL+K+ + TT G
Sbjct: 369 CGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESG 425
Score = 53.9 bits (128), Expect = 9e-07
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 5/163 (3%)
Query: 145 TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE 204
TPLH ASK G + +V LL+ G +I LH + +N + + +L +
Sbjct: 559 TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLL----ENGA 614
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
+ T L A + LL+F AD AGFT LH +G + L
Sbjct: 615 SAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGL 674
Query: 265 LIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKNGFDKN 307
LI++GSD N+G + + + + LY NG + N
Sbjct: 675 LIENGSDVGAKANNGLTAMHLCAQEDHV-PVAQILYNNGAEIN 716
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 150 ASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQP 209
A+++G + V ELL+AG D N +++ G N LH + + +V + + + VD
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVREL----IKRQAQVDAA 95
Query: 210 DPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
TAL A+ +L V L++ A+V GFT L+ + V+ L+KHG
Sbjct: 96 TRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 270 SDFFQTTNDG 279
++ +T DG
Sbjct: 156 ANQALSTEDG 165
>Hs22064845 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 722
Score = 62.0 bits (149), Expect = 3e-09
Identities = 52/186 (27%), Positives = 81/186 (42%), Gaps = 16/186 (8%)
Query: 100 LSNDYDPK----ERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGL 155
+S DP E + LH A +S VK L GAE++ + L TPLH A + G
Sbjct: 457 VSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNL-RTPLHLAVERGK 515
Query: 156 VYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVL----------FFVVDGKED 205
V + LLK+GA P+ D GY LHT+ ++ +L + + +
Sbjct: 516 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLSLQGPPGEIIHLLAESHAN 575
Query: 206 VDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGS-IPVMDL 264
+ T L A + V LL+ AD A+ +G+T LH + + + V++L
Sbjct: 576 MGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINL 635
Query: 265 LIKHGS 270
L H +
Sbjct: 636 LEHHAN 641
Score = 54.7 bits (130), Expect = 5e-07
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH+A N + L GA V+ + E TPLH A+++ + L+ ADPN+
Sbjct: 408 LHFAAQNGDDGTARLLLDHGACVDAQERE-GWTPLHLAAQNNFENVARLLVSRQADPNLH 466
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+++G LH + + ++ LV + ++D + RT L A + +++L
Sbjct: 467 EAEGKTPLHVAAYFGHVSLV----KLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHL 522
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSIPVMDLLI 266
LK A D +G+ LH +G + +L+
Sbjct: 523 LKSGAVPDALDQSGYGPLHTAAARGKYLICKMLL 556
>Hs17864094 [R] KOG0508 Ankyrin repeat protein
Length = 617
Score = 62.0 bits (149), Expect = 3e-09
Identities = 42/138 (30%), Positives = 65/138 (46%), Gaps = 5/138 (3%)
Query: 132 GAEVNFKGGELDATPLHWA-SKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIM 190
G VNF G ++ P WA S +G + +V LL GA N T L + F ++
Sbjct: 71 GGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLE 130
Query: 191 LVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTAL 250
+V Y+ V+ K D++ + H T L + Y+ + LL+ ADV G TAL
Sbjct: 131 IVKYL----VEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTAL 186
Query: 251 HWGTVKGSIPVMDLLIKH 268
H GS+ +M +L+ +
Sbjct: 187 HDCAESGSLDIMKMLLMY 204
>At1g07710 [R] KOG0504 FOG: Ankyrin repeat
Length = 543
Score = 61.2 bits (147), Expect = 6e-09
Identities = 57/204 (27%), Positives = 91/204 (43%), Gaps = 21/204 (10%)
Query: 75 ERYHAACKQGDMKTLREMVESK-----VIDLSNDYDPKERVSGLHWACINNRLSAVKYLA 129
+ +H A KQGD+ L+ + E+ +DLSN + LH A V +L
Sbjct: 103 DAFHIAAKQGDLDVLKVLAEAHSELAMTVDLSN-------TTALHTAATQGHTEVVNFLL 155
Query: 130 GAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT---DSQGYNLLHTSVFS 186
G+ + T LH AS++G V ++ LL ++P I D +G LH +V
Sbjct: 156 ELGSSLAGIAKSNGKTALHSASRNGHVKVIKALL--ASEPAIAIRMDKKGQTALHMAVKG 213
Query: 187 SNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFN-ADVKNADDA 245
+N+ +V + + + ++ D TAL A + + V+ LL N D K + +
Sbjct: 214 TNVEVVEEL---IKADRSSINIADTKGNTALHIAARKGRSQIVKLLLANNMTDTKAVNRS 270
Query: 246 GFTALHWGTVKGSIPVMDLLIKHG 269
G TAL G+ V +L KHG
Sbjct: 271 GETALDTAEKIGNPEVALILQKHG 294
>Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1267
Score = 60.8 bits (146), Expect = 7e-09
Identities = 51/193 (26%), Positives = 92/193 (47%), Gaps = 7/193 (3%)
Query: 75 ERYHAACKQGDM-KTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
++ + + +QG++ K L +V+ ID + + + + S LH A + L AGA
Sbjct: 709 KQLYFSARQGELQKVLLMLVDG--IDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGA 766
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
++ E TPL A+++ + V L+KAGA + D++G LH + + +V
Sbjct: 767 NID-TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQ 825
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWG 253
Y+L +G+ DV+ D T + WAT V+ LL +D+ D+ LHW
Sbjct: 826 YLLS---NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWA 882
Query: 254 TVKGSIPVMDLLI 266
G + + ++L+
Sbjct: 883 AFSGCVDIAEILL 895
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/233 (25%), Positives = 100/233 (42%), Gaps = 12/233 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
HAA + G + +V++ + D +++ + L A NN L AVKYL AGA V+
Sbjct: 747 HAAAEAGHVDICHMLVQAGA---NIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 803
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGA-DPNITDSQGYNLLHTSVFSSNIMLVIYVL 196
K E +T LH A+K G +V LL G D N D G+ + + ++ LV +L
Sbjct: 804 KDAE-GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLL 862
Query: 197 FFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVK 256
D++ D + L WA + E LL D+ + G + LH +
Sbjct: 863 ----SKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARE 918
Query: 257 GSIPVMDLLIKHGSDFFQTTNDGK---NCFTIGKELYSIGSLEASLYKNGFDK 306
+ L + SD +G+ C ++ +++S + +L + D+
Sbjct: 919 NRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDR 971
Score = 53.5 bits (127), Expect = 1e-06
Identities = 52/197 (26%), Positives = 87/197 (43%), Gaps = 8/197 (4%)
Query: 90 REMVESKVIDLSNDYDPKERV--SGLHWACINNRLSAVKYLAGAGAEVNFKGGELDA-TP 146
+E +ES +I L ++ K R L+++ L V + G + NFK + +P
Sbjct: 686 KETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSP 745
Query: 147 LHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDV 206
LH A+++G V I L++AGA+ + L + ++++ V Y+ + V
Sbjct: 746 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYL----IKAGALV 801
Query: 207 DQPDPHQRTALQWATYQADALTVENLLKFNA-DVKNADDAGFTALHWGTVKGSIPVMDLL 265
D D T L A + V+ LL DV DD G+T + W T + ++ LL
Sbjct: 802 DPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLL 861
Query: 266 IKHGSDFFQTTNDGKNC 282
+ GSD N+ C
Sbjct: 862 LSKGSDINIRDNEENIC 878
>Hs10947042 [M] KOG4177 Ankyrin
Length = 1719
Score = 60.5 bits (145), Expect = 9e-09
Identities = 62/204 (30%), Positives = 88/204 (42%), Gaps = 17/204 (8%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC N + ++ L GA ++ E TPLH AS G + IV LL+ GA PN++
Sbjct: 375 LHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+ + LH + + + + Y+L K V+ +T L A V+ L
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLL----QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSI-PVMDLLIKHGSDFFQTTNDGKNCFT------- 284
L+ NA+ A AG T LH +G + V+ LL K S T K FT
Sbjct: 490 LENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT----KKGFTPLHVAAK 545
Query: 285 IGKELYSIGSLEASLYKNGFDKNG 308
GK + LE + N KNG
Sbjct: 546 YGKVRVAELLLERDAHPNAAGKNG 569
Score = 58.5 bits (140), Expect = 4e-08
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 12/206 (5%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
L H A K+G +K + E++ ++I + K+ + LH A + + V+ L GA
Sbjct: 46 LNGLHLASKEGHVKMVVELLHKEII---LETTTKKGNTALHIAALAGQDEVVRELVNYGA 102
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
VN + + TPL+ A++ + +V LL+ GA+ N+ G+ L ++ + +V
Sbjct: 103 NVNAQS-QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 161
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWG 253
+++ + GK + AL A D T LL+ + + GFT LH
Sbjct: 162 HLINYGTKGKV--------RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIA 213
Query: 254 TVKGSIPVMDLLIKHGSDFFQTTNDG 279
++ V LL+ G+ T +G
Sbjct: 214 AHYENLNVAQLLLNRGASVNFTPQNG 239
Score = 58.5 bits (140), Expect = 4e-08
Identities = 52/212 (24%), Positives = 81/212 (37%), Gaps = 41/212 (19%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A KQ ++ R +++ S + + + V+ LH A V L A N
Sbjct: 607 HIAAKQNQVEVARSLLQ---YGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL 663
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G + TPLH ++ G V + D L+K G + T GY LH + NI LV +
Sbjct: 664 -GNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKF--- 719
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
LL+ ADV G++ LH +G
Sbjct: 720 ----------------------------------LLQHQADVNAKTKLGYSPLHQAAQQG 745
Query: 258 SIPVMDLLIKHGSDFFQTTNDGKNCFTIGKEL 289
++ LL+K+G+ + ++DG I K L
Sbjct: 746 HTDIVTLLLKNGASPNEVSSDGTTPLAIAKRL 777
Score = 58.2 bits (139), Expect = 5e-08
Identities = 55/202 (27%), Positives = 85/202 (41%), Gaps = 8/202 (3%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A ++G ++T+ ++E + S K+ + LH A ++ + L A N
Sbjct: 508 HIAAREGHVETVLALLEKEA---SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPN- 563
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G+ TPLH A + IV LL G P+ GY LH + + + + +L
Sbjct: 564 AAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQ 623
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
+ + Q T L A + A V LL A+ + +G T LH +G
Sbjct: 624 YGGSANAESVQ----GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 679
Query: 258 SIPVMDLLIKHGSDFFQTTNDG 279
+PV D+LIKHG TT G
Sbjct: 680 HVPVADVLIKHGVMVDATTRMG 701
Score = 53.9 bits (128), Expect = 9e-07
Identities = 44/159 (27%), Positives = 71/159 (43%), Gaps = 9/159 (5%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH A KYL A+VN K + D TPLH A++ G +V LL+ A+PN+
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKD-DQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR--TALQWATYQADALTVE 230
+ G+ LH + ++ V+ +L +++ Q ++ T L A E
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALL------EKEASQACMTKKGFTPLHVAAKYGKVRVAE 553
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
LL+ +A A G T LH ++ ++ LL+ G
Sbjct: 554 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
>Hs10947040 [M] KOG4177 Ankyrin
Length = 1880
Score = 60.5 bits (145), Expect = 9e-09
Identities = 62/204 (30%), Positives = 88/204 (42%), Gaps = 17/204 (8%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC N + ++ L GA ++ E TPLH AS G + IV LL+ GA PN++
Sbjct: 375 LHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+ + LH + + + + Y+L K V+ +T L A V+ L
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLL----QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSI-PVMDLLIKHGSDFFQTTNDGKNCFT------- 284
L+ NA+ A AG T LH +G + V+ LL K S T K FT
Sbjct: 490 LENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT----KKGFTPLHVAAK 545
Query: 285 IGKELYSIGSLEASLYKNGFDKNG 308
GK + LE + N KNG
Sbjct: 546 YGKVRVAELLLERDAHPNAAGKNG 569
Score = 58.5 bits (140), Expect = 4e-08
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 12/206 (5%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
L H A K+G +K + E++ ++I + K+ + LH A + + V+ L GA
Sbjct: 46 LNGLHLASKEGHVKMVVELLHKEII---LETTTKKGNTALHIAALAGQDEVVRELVNYGA 102
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
VN + + TPL+ A++ + +V LL+ GA+ N+ G+ L ++ + +V
Sbjct: 103 NVNAQS-QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 161
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWG 253
+++ + GK + AL A D T LL+ + + GFT LH
Sbjct: 162 HLINYGTKGKV--------RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIA 213
Query: 254 TVKGSIPVMDLLIKHGSDFFQTTNDG 279
++ V LL+ G+ T +G
Sbjct: 214 AHYENLNVAQLLLNRGASVNFTPQNG 239
Score = 58.5 bits (140), Expect = 4e-08
Identities = 52/212 (24%), Positives = 81/212 (37%), Gaps = 41/212 (19%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A KQ ++ R +++ S + + + V+ LH A V L A N
Sbjct: 607 HIAAKQNQVEVARSLLQ---YGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL 663
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G + TPLH ++ G V + D L+K G + T GY LH + NI LV +
Sbjct: 664 -GNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKF--- 719
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
LL+ ADV G++ LH +G
Sbjct: 720 ----------------------------------LLQHQADVNAKTKLGYSPLHQAAQQG 745
Query: 258 SIPVMDLLIKHGSDFFQTTNDGKNCFTIGKEL 289
++ LL+K+G+ + ++DG I K L
Sbjct: 746 HTDIVTLLLKNGASPNEVSSDGTTPLAIAKRL 777
Score = 58.2 bits (139), Expect = 5e-08
Identities = 55/202 (27%), Positives = 85/202 (41%), Gaps = 8/202 (3%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A ++G ++T+ ++E + S K+ + LH A ++ + L A N
Sbjct: 508 HIAAREGHVETVLALLEKEA---SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPN- 563
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G+ TPLH A + IV LL G P+ GY LH + + + + +L
Sbjct: 564 AAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQ 623
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
+ + Q T L A + A V LL A+ + +G T LH +G
Sbjct: 624 YGGSANAESVQ----GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 679
Query: 258 SIPVMDLLIKHGSDFFQTTNDG 279
+PV D+LIKHG TT G
Sbjct: 680 HVPVADVLIKHGVMVDATTRMG 701
Score = 53.9 bits (128), Expect = 9e-07
Identities = 44/159 (27%), Positives = 71/159 (43%), Gaps = 9/159 (5%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH A KYL A+VN K + D TPLH A++ G +V LL+ A+PN+
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKD-DQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR--TALQWATYQADALTVE 230
+ G+ LH + ++ V+ +L +++ Q ++ T L A E
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALL------EKEASQACMTKKGFTPLHVAAKYGKVRVAE 553
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
LL+ +A A G T LH ++ ++ LL+ G
Sbjct: 554 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
>Hs10947038 [M] KOG4177 Ankyrin
Length = 1881
Score = 60.5 bits (145), Expect = 9e-09
Identities = 62/204 (30%), Positives = 88/204 (42%), Gaps = 17/204 (8%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC N + ++ L GA ++ E TPLH AS G + IV LL+ GA PN++
Sbjct: 375 LHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+ + LH + + + + Y+L K V+ +T L A V+ L
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLL----QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSI-PVMDLLIKHGSDFFQTTNDGKNCFT------- 284
L+ NA+ A AG T LH +G + V+ LL K S T K FT
Sbjct: 490 LENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT----KKGFTPLHVAAK 545
Query: 285 IGKELYSIGSLEASLYKNGFDKNG 308
GK + LE + N KNG
Sbjct: 546 YGKVRVAELLLERDAHPNAAGKNG 569
Score = 58.5 bits (140), Expect = 4e-08
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 12/206 (5%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
L H A K+G +K + E++ ++I + K+ + LH A + + V+ L GA
Sbjct: 46 LNGLHLASKEGHVKMVVELLHKEII---LETTTKKGNTALHIAALAGQDEVVRELVNYGA 102
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
VN + + TPL+ A++ + +V LL+ GA+ N+ G+ L ++ + +V
Sbjct: 103 NVNAQS-QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 161
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWG 253
+++ + GK + AL A D T LL+ + + GFT LH
Sbjct: 162 HLINYGTKGKV--------RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIA 213
Query: 254 TVKGSIPVMDLLIKHGSDFFQTTNDG 279
++ V LL+ G+ T +G
Sbjct: 214 AHYENLNVAQLLLNRGASVNFTPQNG 239
Score = 58.5 bits (140), Expect = 4e-08
Identities = 52/212 (24%), Positives = 81/212 (37%), Gaps = 41/212 (19%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A KQ ++ R +++ S + + + V+ LH A V L A N
Sbjct: 607 HIAAKQNQVEVARSLLQ---YGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL 663
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G + TPLH ++ G V + D L+K G + T GY LH + NI LV +
Sbjct: 664 -GNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKF--- 719
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
LL+ ADV G++ LH +G
Sbjct: 720 ----------------------------------LLQHQADVNAKTKLGYSPLHQAAQQG 745
Query: 258 SIPVMDLLIKHGSDFFQTTNDGKNCFTIGKEL 289
++ LL+K+G+ + ++DG I K L
Sbjct: 746 HTDIVTLLLKNGASPNEVSSDGTTPLAIAKRL 777
Score = 58.2 bits (139), Expect = 5e-08
Identities = 55/202 (27%), Positives = 85/202 (41%), Gaps = 8/202 (3%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A ++G ++T+ ++E + S K+ + LH A ++ + L A N
Sbjct: 508 HIAAREGHVETVLALLEKEA---SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPN- 563
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G+ TPLH A + IV LL G P+ GY LH + + + + +L
Sbjct: 564 AAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQ 623
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
+ + Q T L A + A V LL A+ + +G T LH +G
Sbjct: 624 YGGSANAESVQ----GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 679
Query: 258 SIPVMDLLIKHGSDFFQTTNDG 279
+PV D+LIKHG TT G
Sbjct: 680 HVPVADVLIKHGVMVDATTRMG 701
Score = 53.9 bits (128), Expect = 9e-07
Identities = 44/159 (27%), Positives = 71/159 (43%), Gaps = 9/159 (5%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH A KYL A+VN K + D TPLH A++ G +V LL+ A+PN+
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKD-DQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR--TALQWATYQADALTVE 230
+ G+ LH + ++ V+ +L +++ Q ++ T L A E
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALL------EKEASQACMTKKGFTPLHVAAKYGKVRVAE 553
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
LL+ +A A G T LH ++ ++ LL+ G
Sbjct: 554 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
>Hs10947036 [M] KOG4177 Ankyrin
Length = 1856
Score = 60.5 bits (145), Expect = 9e-09
Identities = 62/204 (30%), Positives = 88/204 (42%), Gaps = 17/204 (8%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC N + ++ L GA ++ E TPLH AS G + IV LL+ GA PN++
Sbjct: 375 LHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
+ + LH + + + + Y+L K V+ +T L A V+ L
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLL----QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSI-PVMDLLIKHGSDFFQTTNDGKNCFT------- 284
L+ NA+ A AG T LH +G + V+ LL K S T K FT
Sbjct: 490 LENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT----KKGFTPLHVAAK 545
Query: 285 IGKELYSIGSLEASLYKNGFDKNG 308
GK + LE + N KNG
Sbjct: 546 YGKVRVAELLLERDAHPNAAGKNG 569
Score = 58.5 bits (140), Expect = 4e-08
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 12/206 (5%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
L H A K+G +K + E++ ++I + K+ + LH A + + V+ L GA
Sbjct: 46 LNGLHLASKEGHVKMVVELLHKEII---LETTTKKGNTALHIAALAGQDEVVRELVNYGA 102
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
VN + + TPL+ A++ + +V LL+ GA+ N+ G+ L ++ + +V
Sbjct: 103 NVNAQS-QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 161
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWG 253
+++ + GK + AL A D T LL+ + + GFT LH
Sbjct: 162 HLINYGTKGKV--------RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIA 213
Query: 254 TVKGSIPVMDLLIKHGSDFFQTTNDG 279
++ V LL+ G+ T +G
Sbjct: 214 AHYENLNVAQLLLNRGASVNFTPQNG 239
Score = 58.5 bits (140), Expect = 4e-08
Identities = 52/212 (24%), Positives = 81/212 (37%), Gaps = 41/212 (19%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A KQ ++ R +++ S + + + V+ LH A V L A N
Sbjct: 607 HIAAKQNQVEVARSLLQ---YGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL 663
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G + TPLH ++ G V + D L+K G + T GY LH + NI LV +
Sbjct: 664 -GNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKF--- 719
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
LL+ ADV G++ LH +G
Sbjct: 720 ----------------------------------LLQHQADVNAKTKLGYSPLHQAAQQG 745
Query: 258 SIPVMDLLIKHGSDFFQTTNDGKNCFTIGKEL 289
++ LL+K+G+ + ++DG I K L
Sbjct: 746 HTDIVTLLLKNGASPNEVSSDGTTPLAIAKRL 777
Score = 58.2 bits (139), Expect = 5e-08
Identities = 55/202 (27%), Positives = 85/202 (41%), Gaps = 8/202 (3%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A ++G ++T+ ++E + S K+ + LH A ++ + L A N
Sbjct: 508 HIAAREGHVETVLALLEKEA---SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPN- 563
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
G+ TPLH A + IV LL G P+ GY LH + + + + +L
Sbjct: 564 AAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQ 623
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKG 257
+ + Q T L A + A V LL A+ + +G T LH +G
Sbjct: 624 YGGSANAESVQ----GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 679
Query: 258 SIPVMDLLIKHGSDFFQTTNDG 279
+PV D+LIKHG TT G
Sbjct: 680 HVPVADVLIKHGVMVDATTRMG 701
Score = 53.9 bits (128), Expect = 9e-07
Identities = 44/159 (27%), Positives = 71/159 (43%), Gaps = 9/159 (5%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH A KYL A+VN K + D TPLH A++ G +V LL+ A+PN+
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKD-DQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR--TALQWATYQADALTVE 230
+ G+ LH + ++ V+ +L +++ Q ++ T L A E
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALL------EKEASQACMTKKGFTPLHVAAKYGKVRVAE 553
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHG 269
LL+ +A A G T LH ++ ++ LL+ G
Sbjct: 554 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
>Hs4557799 [T] KOG1217 Fibrillins and related proteins containing Ca2+-binding
EGF-like domains
Length = 2321
Score = 60.1 bits (144), Expect = 1e-08
Identities = 52/177 (29%), Positives = 80/177 (44%), Gaps = 8/177 (4%)
Query: 123 SAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHT 182
S + L GA++ + T LH A++ LL AGAD N D G LHT
Sbjct: 1819 SIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHT 1878
Query: 183 SVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNA 242
+V +++ V +L + + D+D TAL A A VE L+ +ADV
Sbjct: 1879 AV-TADAQGVFQIL--IRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAV 1935
Query: 243 DDAGFTALHWGTVKGSIPVMDLLIKHGSD-FFQTTNDGKNCFTIGKELYSIGSLEAS 298
D+ G +ALHW ++ L+K+G++ Q + + F +E GS EA+
Sbjct: 1936 DELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAARE----GSYEAA 1988
>Hs14249672 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 528
Score = 60.1 bits (144), Expect = 1e-08
Identities = 56/218 (25%), Positives = 98/218 (44%), Gaps = 31/218 (14%)
Query: 80 ACKQGDMKTLREMVESKVI-DLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFK 138
A + D++ +R+ + S V DL+N+ + ++ LH CI++ V+ L AGA +N
Sbjct: 78 AAARNDLEEVRQFLGSGVSPDLANE----DGLTALHQCCIDDFREMVQQLLEAGANINAC 133
Query: 139 GGELDATPLHWASKSGLVYIVDELLKAGA-------DPNIT-----DSQGYNLLHTSVFS 186
E TPLH A+ G +++V+ L+ +GA D N+ D Q + L T++
Sbjct: 134 DSEC-WTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMAD 192
Query: 187 SNI-------------MLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLL 233
I + ++ + + D+ P H T L A + LL
Sbjct: 193 RGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLL 252
Query: 234 KFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
+ A + D G+ LH G +P+++LL+ HG+D
Sbjct: 253 EHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGAD 290
>At2g14250 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 192
Score = 59.7 bits (143), Expect = 2e-08
Identities = 34/90 (37%), Positives = 48/90 (52%), Gaps = 1/90 (1%)
Query: 182 TSVFSSNIMLVIYVL-FFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVK 240
T VFS++ ++ L FV V PD + ALQWA + +++ DV
Sbjct: 26 TDVFSASAYGDLHQLKHFVEHNGSSVSLPDDNGFYALQWAALNNSLHVAQYIIQHGGDVN 85
Query: 241 NADDAGFTALHWGTVKGSIPVMDLLIKHGS 270
+AD+ T LHW VKGSI V DLL++HG+
Sbjct: 86 SADNIQQTPLHWAAVKGSIDVADLLLQHGA 115
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/192 (26%), Positives = 73/192 (37%), Gaps = 26/192 (13%)
Query: 67 SVEKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVK 126
S + P + +A GD+ L+ VE +S D L WA +NN L +
Sbjct: 18 SPTESPTITDVFSASAYGDLHQLKHFVEHNGSSVSLPDD--NGFYALQWAALNNSLHVAQ 75
Query: 127 YLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFS 186
Y+ G +VN + TPLHWA+ G + + D LL+ GA D G+ +
Sbjct: 76 YIIQHGGDVN-SADNIQQTPLHWAAVKGSIDVADLLLQHGARIEAVDVNGFR----ACCC 130
Query: 187 SNIMLVIYVLF------FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVK 240
+ L I V F FVV Q Y A ++ + AD
Sbjct: 131 CDHRLQILVRFCRSTTCFVVQAVHVASQ-------------YGQTAFVNHIIVDYAADYN 177
Query: 241 NADDAGFTALHW 252
D G + LHW
Sbjct: 178 ALDIEGRSPLHW 189
>CE26238_1 [M] KOG4177 Ankyrin
Length = 1294
Score = 58.9 bits (141), Expect = 3e-08
Identities = 43/159 (27%), Positives = 75/159 (47%), Gaps = 9/159 (5%)
Query: 103 DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVD-- 160
D ++ + LH A + + S V+ L G+GA+++ KGGEL T LH A+ D
Sbjct: 606 DVRTRDNYTALHVAVQSGKASVVETLLGSGADIHVKGGELGQTALHIAASLNGAESRDCA 665
Query: 161 -ELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQW 219
LLK+G P++ G LH + S N ++ +L D K + + A +
Sbjct: 666 MMLLKSGGQPDVAQMDGETCLHIAARSGNKDIMRLLLDENADSKISSKIGETPLQVAAKS 725
Query: 220 ATYQADALTVENLL------KFNADVKNADDAGFTALHW 252
++A ++ +++L + V + + GFTALH+
Sbjct: 726 CNFEAASMILKHLSEVLTQEQLKEHVNHRTNDGFTALHY 764
>Hs18551475 [R] KOG0504 FOG: Ankyrin repeat
Length = 258
Score = 58.5 bits (140), Expect = 4e-08
Identities = 50/170 (29%), Positives = 76/170 (44%), Gaps = 7/170 (4%)
Query: 74 LERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGA 133
L + H A +G L M++ +DL N D K+R + L+WAC N V L
Sbjct: 39 LRKIHKAASRGQAWKLERMMKKTTMDL-NIRDAKKRTA-LYWACANGHAEVVTLLVDRKC 96
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVI 193
+++ GE + T L A + + L+ +GADPNI D G +H +V S N+ +V
Sbjct: 97 QLDVLDGE-NRTILMKALQCQREACANILIDSGADPNIVDVYGNTAVHYAVNSENLSVVA 155
Query: 194 YVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNAD 243
+L D++ + T L A + VE LL NA+ D
Sbjct: 156 KLL----SCGADIEVKNKAGHTPLLLAIRKRSEEIVEFLLTKNANANAVD 201
>Hs14770818 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 567
Score = 58.5 bits (140), Expect = 4e-08
Identities = 71/281 (25%), Positives = 113/281 (39%), Gaps = 43/281 (15%)
Query: 36 VVSLDSMKAVISRASSELK----HEND-------QGEERDLGSVEKDPILERYHA---AC 81
V +L+ ++A R + +LK +E D +R G K E A A
Sbjct: 17 VPTLERLRAAQKRRAQQLKKWAQYEQDLQHRKRKHERKRSTGGRRKKVSFEASVALLEAS 76
Query: 82 KQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGE 141
+ D + +R +++KV S D ++ ++ LH CI+N VK L GA VN K E
Sbjct: 77 LRNDAEEVRYFLKNKV---SPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNE 133
Query: 142 LDATPLHWASKSGLVYIVDELLKAGADPNITDSQG------------YNLLHTSVFSSNI 189
L TPLH A+ G + +V L++ GAD +S G +++ T + I
Sbjct: 134 L-WTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGI 192
Query: 190 -------------MLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFN 236
+I + ++ +D+D D T L A E LL
Sbjct: 193 TQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHG 252
Query: 237 ADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTN 277
V D G+ LH G + + +LL+ HG+ T+
Sbjct: 253 VRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTS 293
>7301689 [R] KOG0504 FOG: Ankyrin repeat
Length = 2119
Score = 58.5 bits (140), Expect = 4e-08
Identities = 54/195 (27%), Positives = 86/195 (43%), Gaps = 10/195 (5%)
Query: 78 HAACKQGDMKTLREMVES--KVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEV 135
H A +G + +++ES K+ + N E + LH A RL V+ L +
Sbjct: 1556 HYAAFEGFHEVCLQLLESGAKIDECDN-----EGKTALHLAAQEGRLHCVQALLDIHSSF 1610
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
+ T A G + V+ LLK D N D+ L+ + + +V Y+
Sbjct: 1611 VDQKAHDGKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYL 1670
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTV 255
L DV+ PD RTAL A +Q A V+ L++ ADV + D T LH
Sbjct: 1671 LDMT---NVDVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAW 1727
Query: 256 KGSIPVMDLLIKHGS 270
+G+ VM++L+ +G+
Sbjct: 1728 QGNHDVMNILLYYGA 1742
Score = 55.5 bits (132), Expect = 3e-07
Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 4/155 (2%)
Query: 145 TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE 204
+PL +S G + + LL+ ADP++ D G L + + + +V +LF+
Sbjct: 1454 SPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCG--- 1510
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
+D D RT L Q + TV LL D + D+AG+T LH+ +G V
Sbjct: 1511 -IDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQ 1569
Query: 265 LIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASL 299
L++ G+ + N+GK + + + ++A L
Sbjct: 1570 LLESGAKIDECDNEGKTALHLAAQEGRLHCVQALL 1604
>7290390 [T] KOG1217 Fibrillins and related proteins containing Ca2+-binding
EGF-like domains
Length = 2634
Score = 58.5 bits (140), Expect = 4e-08
Identities = 54/171 (31%), Positives = 79/171 (45%), Gaps = 8/171 (4%)
Query: 128 LAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSS 187
L GAE+N + T LH A++ LL AGAD N D+ G LH +V ++
Sbjct: 1936 LLAQGAELNATMDKTGETSLHLAARFARADAAKRLLDAGADANCQDNTGRTPLHAAV-AA 1994
Query: 188 NIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGF 247
+ M V +L + + +++ T L A A VE+L+ +AD+ AD++G
Sbjct: 1995 DAMGVFQIL--LRNRATNLNARMHDGTTPLILAARLAIEGMVEDLITADADINAADNSGK 2052
Query: 248 TALHW-GTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEA 297
TALHW V + V LL+ H + Q D F +E GS EA
Sbjct: 2053 TALHWAAAVNNTEAVNILLMHHANRDAQDDKDETPLFLAARE----GSYEA 2099
>7294199_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 708
Score = 58.5 bits (140), Expect = 4e-08
Identities = 48/194 (24%), Positives = 91/194 (46%), Gaps = 11/194 (5%)
Query: 79 AACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFK 138
AA + G ++ ++ ++ V + + K+ +H A + + ++ LA AGA++N +
Sbjct: 71 AASQNGHIEVIQVLLRHAV---DVEIEDKDGDRAVHHAAFGDEAAVIEILAKAGADLNAR 127
Query: 139 GGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFF 198
T LH A G + +V LL G P++ DS+G LH ++ + + L
Sbjct: 128 NKRRQ-TSLHIAVNKGHLNVVKTLLTLGCHPSLQDSEGDTPLHDAISKEHDEM----LSL 182
Query: 199 VVDGKEDVDQPDPHQRTALQWATYQADALTVENLL-KFNAD--VKNADDAGFTALHWGTV 255
++D D+ + + AL A + + ++ LL K N V+ D G+TALH +
Sbjct: 183 LLDFGADITLNNNNGFNALHHAALKGNPSAMKILLTKTNRPWIVEEKKDDGYTALHLAAL 242
Query: 256 KGSIPVMDLLIKHG 269
+ + +LL+ G
Sbjct: 243 NNHVEIAELLVHMG 256
Score = 54.7 bits (130), Expect = 5e-07
Identities = 64/246 (26%), Positives = 101/246 (41%), Gaps = 11/246 (4%)
Query: 64 DLGSVEKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLS 123
D+ +KD +HAA GD + E++ DL+ K R + LH A L+
Sbjct: 90 DVEIEDKDGDRAVHHAAF--GDEAAVIEILAKAGADLNARN--KRRQTSLHIAVNKGHLN 145
Query: 124 AVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTS 183
VK L G + + E D TPLH A ++ LL GAD + ++ G+N LH +
Sbjct: 146 VVKTLLTLGCHPSLQDSEGD-TPLHDAISKEHDEMLSLLLDFGADITLNNNNGFNALHHA 204
Query: 184 VFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLL---KFNADVK 240
N + +L + V++ TAL A E L+ K N D +
Sbjct: 205 ALKGNPS-AMKILLTKTNRPWIVEEKKDDGYTALHLAALNNHVEIAELLVHMGKANMDRQ 263
Query: 241 NADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLY 300
N + TALH + + ++ LL++ G+D DG +++ L+
Sbjct: 264 NVNLQ--TALHLAVERQHVQIVKLLVQDGADLNIPDKDGDTPLHEALRHHTLSQLKQLQD 321
Query: 301 KNGFDK 306
GF K
Sbjct: 322 VEGFGK 327
Score = 53.1 bits (126), Expect = 2e-06
Identities = 43/168 (25%), Positives = 68/168 (39%), Gaps = 16/168 (9%)
Query: 126 KYLAGA------------GAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITD 173
+YLAGA G +VN G T L AS++G + ++ LL+ D I D
Sbjct: 36 EYLAGAAQPSTSSASPSSGPDVNVNGVFAGHTALQAASQNGHIEVIQVLLRHAVDVEIED 95
Query: 174 SQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLL 233
G +H + F V+ + D++ + ++T+L A + V+ LL
Sbjct: 96 KDGDRAVHHAAFGDEAA----VIEILAKAGADLNARNKRRQTSLHIAVNKGHLNVVKTLL 151
Query: 234 KFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKN 281
D G T LH K ++ LL+ G+D N+G N
Sbjct: 152 TLGCHPSLQDSEGDTPLHDAISKEHDEMLSLLLDFGADITLNNNNGFN 199
>Hs14744423 [R] KOG0504 FOG: Ankyrin repeat
Length = 333
Score = 58.2 bits (139), Expect = 5e-08
Identities = 56/245 (22%), Positives = 92/245 (36%), Gaps = 45/245 (18%)
Query: 36 VVSLDSMKAVISRASSELKHENDQGEERDLGSVEKDPILERYHAACKQGDMKTLREMVES 95
++ L + R + HE E G V+++ L+ A +G MK + + +
Sbjct: 88 LIELRKKRKQKKRDALAASHEPPPEPEEITGPVDEETFLK----AAVEGKMKVIEKFLAD 143
Query: 96 KVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGL 155
S D + R + LH A + + ++ L GA V+F+ LD T +HWA + G
Sbjct: 144 GG---SADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQD-RLDCTAMHWACRGGH 199
Query: 156 VYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRT 215
+ +V L GAD N+ D LH +V + + +
Sbjct: 200 LEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEI------------------------ 235
Query: 216 ALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQT 275
VE+ L ++ D G TALH ++ LL+ HG+D
Sbjct: 236 -------------VEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTK 282
Query: 276 TNDGK 280
GK
Sbjct: 283 NLAGK 287
>Hs13540484 [R] KOG0504 FOG: Ankyrin repeat
Length = 333
Score = 58.2 bits (139), Expect = 5e-08
Identities = 56/245 (22%), Positives = 92/245 (36%), Gaps = 45/245 (18%)
Query: 36 VVSLDSMKAVISRASSELKHENDQGEERDLGSVEKDPILERYHAACKQGDMKTLREMVES 95
++ L + R + HE E G V+++ L+ A +G MK + + +
Sbjct: 88 LIELRKKRKQKKRDALAASHEPPPEPEEITGPVDEETFLK----AAVEGKMKVIEKFLAD 143
Query: 96 KVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGL 155
S D + R + LH A + + ++ L GA V+F+ LD T +HWA + G
Sbjct: 144 GG---SADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQD-RLDCTAMHWACRGGH 199
Query: 156 VYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRT 215
+ +V L GAD N+ D LH +V + + +
Sbjct: 200 LEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEI------------------------ 235
Query: 216 ALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQT 275
VE+ L ++ D G TALH ++ LL+ HG+D
Sbjct: 236 -------------VEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTK 282
Query: 276 TNDGK 280
GK
Sbjct: 283 NLAGK 287
>Hs21264330_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 500
Score = 58.2 bits (139), Expect = 5e-08
Identities = 52/191 (27%), Positives = 91/191 (47%), Gaps = 14/191 (7%)
Query: 84 GDMKTLREMVESKV-IDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGEL 142
G ++ +R +++++ +DL +D E + LH+A + N+ A + L AG +
Sbjct: 21 GQVELIRLLLQARAGVDLPDD----EGNTALHYAALGNQPEATRVLLSAGCRADAINST- 75
Query: 143 DATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFS-SNIMLVIYVLFFVVD 201
+T LH A + G + +V L + G D N+ D+ LH+++ + + ++ VL V +
Sbjct: 76 QSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPN 135
Query: 202 GKEDVDQPDPHQRTALQWATYQADALTVENLL---KFNADVKNADDAGFTALHWGTVKGS 258
DV + T L A+ + AL V +L + D K D GFTALH +
Sbjct: 136 --IDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKED--GFTALHLAALNNH 191
Query: 259 IPVMDLLIKHG 269
V +LI+ G
Sbjct: 192 REVAQILIREG 202
>7298524_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 611
Score = 57.8 bits (138), Expect = 6e-08
Identities = 46/166 (27%), Positives = 74/166 (43%), Gaps = 9/166 (5%)
Query: 107 KERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAG 166
KE S LH+A N+ + ++ L GAEVNF + LH + + V ELL+
Sbjct: 57 KEGDSALHYAAFGNQPATMRVLLQHGAEVNFLNSS-HCSALHICAHKKTPHCVRELLQHN 115
Query: 167 ADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR--TALQWATYQA 224
A+ NI DS G LH ++ N +V ++ ++D + R L A +
Sbjct: 116 ANVNIQDSYGDTALHDAIGKENTEVV-----ELLCNAPNLDFTVKNNRGFNVLHHAALKG 170
Query: 225 DALTVENLLKFNADVKNA-DDAGFTALHWGTVKGSIPVMDLLIKHG 269
+ + +L + + N D GF ALH + G V++ L+ G
Sbjct: 171 NVVAARRILLLSRQLVNVRKDDGFAALHLAALNGHAQVVETLVTEG 216
>ECU10g0720 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 393
Score = 57.4 bits (137), Expect = 8e-08
Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 4/121 (3%)
Query: 100 LSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIV 159
+ NDY + +HWA + N L + L G VN GG LD++PL++A + ++
Sbjct: 52 IPNDYRFSDGTGLIHWASMYNNLDVCRRLVGCHGAVNSVGGVLDSSPLYYALYNSNYRVM 111
Query: 160 DELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQW 219
L++ GAD + G LLHT +++ ++ +L D+ D +RT +
Sbjct: 112 KLLIEHGADITYVNKSGLGLLHTCARFDDVLGMVLLL----SHGADIGVRDTRKRTLWTY 167
Query: 220 A 220
A
Sbjct: 168 A 168
>7301359 [M] KOG4177 Ankyrin
Length = 1181
Score = 57.4 bits (137), Expect = 8e-08
Identities = 54/221 (24%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 71 DPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAG 130
DP+ E + A CK G++ +++++ + ++ + K + LH+A R V++L
Sbjct: 22 DPLRELFEA-CKTGEIAKVKKLITPQTVNARDTAGRKS--TPLHFAAGYGRREVVEFLLN 78
Query: 131 AGAEVNF--KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSN 188
+GA + +GG PLH G +V LLKAGA PN TD+ Y LH +
Sbjct: 79 SGASIQACDEGG---LHPLHNCCSFGHAEVVRLLLKAGASPNTTDNWNYTPLHEAASKGK 135
Query: 189 IMLVIYVLFFVV-------DGKEDVDQPDPHQRTALQWATYQADAL-----------TVE 230
+ + + +L + K ++ D R L Y+ D L +
Sbjct: 136 VDVCLALLQHGANHTIRNSEQKTPLELADEATRPVLT-GEYRKDELLEAARSGAEDRLLA 194
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
L N + +D T LH I ++++L+ +G+D
Sbjct: 195 LLTPLNVNCHASDGRRSTPLHLAAGYNRIGIVEILLANGAD 235
>Hs6601590 [R] KOG0510 Ankyrin repeat protein
Length = 1119
Score = 57.0 bits (136), Expect = 1e-07
Identities = 66/232 (28%), Positives = 99/232 (42%), Gaps = 15/232 (6%)
Query: 78 HAACKQGDMKTLREMVESKV--IDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEV 135
H A QG + ++ M+ S +D+ N D LH A + + YL GA++
Sbjct: 277 HFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETM-LHRASLFDHHELADYLISVGADI 335
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
N E +PL A+ S IV+ LL GA +I D+ G N LH +V + +
Sbjct: 336 NKIDSE-GRSPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRP 394
Query: 196 LFFVVDG-KEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGT 254
F + KE V D T L +A Q +V NLL FN + + + LH+
Sbjct: 395 EFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAA 454
Query: 255 VKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKNGFDK 306
G I L++ SD + N+G +L+ + L + KNG DK
Sbjct: 455 SYGRINTCQRLLQDISD-TRLLNEG--------DLHGMTPLHLAA-KNGHDK 496
Score = 51.6 bits (122), Expect = 4e-06
Identities = 55/179 (30%), Positives = 80/179 (43%), Gaps = 12/179 (6%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H AC+QG ++ ++ V S D K S LH+A R++ + L ++
Sbjct: 418 HYACRQGGPGSVNNLLGFNVSIHSKSKDKK---SPLHFAASYGRINTCQRLLQDISDTRL 474
Query: 138 KG-GELDA-TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
G+L TPLH A+K+G +V LLK GA ++D G+ LH + + +
Sbjct: 475 LNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVI 533
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNAD-VKNADDAGF--TALH 251
L + D+ D TAL +A + A V LL NAD V N A F ALH
Sbjct: 534 L---DTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALH 589
>Hs14720884 [R] KOG0504 FOG: Ankyrin repeat
Length = 823
Score = 57.0 bits (136), Expect = 1e-07
Identities = 55/212 (25%), Positives = 86/212 (39%), Gaps = 7/212 (3%)
Query: 70 KDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLA 129
+D L++ H A +GD + + + DL D K+ + LH AC + + V L
Sbjct: 30 RDSELQKIHRAAVKGDAAEVERCLARRSGDL--DARDKQHRTALHLACASGHVQVVTLLV 87
Query: 130 GAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNI 189
+++ E + TPL A LLK GA+PN+ D G LH +V+S +
Sbjct: 88 NRKCQIDICDKE-NRTPLIQAVHCQEEACAVILLKHGANPNLKDIYGNTALHYAVYSEST 146
Query: 190 MLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTA 249
L +L ++ D T L +A VE LLK A D +A
Sbjct: 147 SLAEKLL----SHGAHIEALDKDSNTPLLFAIICKKEKMVEFLLKKKASTHAVDRLRRSA 202
Query: 250 LHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKN 281
L S ++ +L+K D F G++
Sbjct: 203 LMLAVYYDSPGIVSILLKQNIDVFAQDMCGRD 234
>CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 850
Score = 57.0 bits (136), Expect = 1e-07
Identities = 52/199 (26%), Positives = 94/199 (47%), Gaps = 7/199 (3%)
Query: 73 ILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAG 132
+L H A GD + L ++ S D+ + LH A + +AV+ L A
Sbjct: 150 LLPALHLAAMIGDSEMLTILLNSGANIHVTDF---VHFTALHCATYFGQENAVRTLISAS 206
Query: 133 AEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLV 192
A +N GG ++ P+H A+ GL I LL+A ADP + D +G LH + S +++++
Sbjct: 207 ANLNL-GGAVNDRPIHLAAAKGLTSITKLLLEAKADPLLADDEGNQALHYAAKSGSLVIL 265
Query: 193 IYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFN-ADVKNADDA-GFTAL 250
++ V + + + + TAL + Y V+++L + ++ N ++ T L
Sbjct: 266 NMLIKQVRGTNDRICARNLYGDTALHLSCYSGRLDIVKSILDSSPTNIVNMENVFSETPL 325
Query: 251 HWGTVKG-SIPVMDLLIKH 268
H G SI ++ L+K+
Sbjct: 326 HAACTGGKSIELVSFLMKY 344
>Hs14764060 [R] KOG0508 Ankyrin repeat protein
Length = 669
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/153 (28%), Positives = 69/153 (44%), Gaps = 11/153 (7%)
Query: 122 LSAVKYLAG-------AGAEVNFKGGELDATPLHWA-SKSGLVYIVDELLKAGADPNITD 173
L V+YL AG V+F G ++ P WA S +G + +V LL+ GA N T
Sbjct: 54 LDVVEYLVDRCGASVEAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTT 113
Query: 174 SQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLL 233
L + F ++ +V Y+ V + + D++ + H T L + Y+ LL
Sbjct: 114 RTNSTPLRAACFDGHLEVVRYL---VGEHQADLEVANRHGHTCLMISCYKGHREIARYLL 170
Query: 234 KFNADVKNADDAGFTALHWGTVKGSIPVMDLLI 266
+ A V G TALH GS+ ++ LL+
Sbjct: 171 EQGAQVNRRSAKGNTALHDCAESGSLEILQLLL 203
>7291939 [R] KOG0510 Ankyrin repeat protein
Length = 904
Score = 56.6 bits (135), Expect = 1e-07
Identities = 58/208 (27%), Positives = 87/208 (40%), Gaps = 8/208 (3%)
Query: 102 NDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDE 161
N +D ++ V+ LH A + + + L A +N G + LH+A V V+
Sbjct: 167 NRWDARKEVTSLHCAASSKSVECILLLLRRKASINI--GIEKRSALHYAIDVNAVDCVEI 224
Query: 162 LLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWAT 221
LLK GADPN LHT+ + V +L D + + + TAL A
Sbjct: 225 LLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNADVRSQFGEG---KVTALHLAA 281
Query: 222 YQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKN 281
LL+ A+V + + T LH + SI +DLLI +G++ DG+
Sbjct: 282 ENDYVECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTVDLLISYGANVNAVYRDGRT 341
Query: 282 CF--TIGKELYSIGSLEASLYKNGFDKN 307
I K+ S+ A L K G D N
Sbjct: 342 ALHAAIVKQSRSLDCCNA-LLKAGADVN 368
>CE05814 [R] KOG0502 Integral membrane ankyrin-repeat protein Kidins220
(protein kinase D substrate)
Length = 1398
Score = 56.2 bits (134), Expect = 2e-07
Identities = 40/123 (32%), Positives = 64/123 (51%), Gaps = 7/123 (5%)
Query: 150 ASKSGLVYIVDELLKAGADP-NITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQ 208
A +SG + +L + D + TD++G++ L + ++ +V ++D VDQ
Sbjct: 69 AVRSGNTAVAKQLAQLDPDAIDETDNEGWSALLNAAHCGHVDIVR----LLIDNGASVDQ 124
Query: 209 PDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKH 268
PD + L WA Y+ + L V +LL NA V D G TAL W KG +PV+ LL+
Sbjct: 125 PDLMGWSPLMWAVYK-NHLDVVDLL-VNAKVNACDKFGSTALIWAARKGHLPVVQLLLNS 182
Query: 269 GSD 271
G++
Sbjct: 183 GAE 185
>CE05333 [R] KOG0510 Ankyrin repeat protein
Length = 1188
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 16/203 (7%)
Query: 69 EKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYL 128
E D + H + ++G++ L+E + L+ + + ++ LH+A AVK L
Sbjct: 28 EADNLRSIIHQSAREGNVNALQEALLKA--PLAVNAQDGDFMTPLHYAARYGNYDAVKLL 85
Query: 129 AGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSN 188
A N K E D TPLH ASK +Y ++ + ++ YN + ++
Sbjct: 86 LSKNALPNTKNREGD-TPLHIASK--YIYGYSDICSIIDEDQADSARKYNTATKKIINA- 141
Query: 189 IMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFT 248
+V ++D + +Q T L +A +++ + L+K ADV DD T
Sbjct: 142 ----------LVSENAEIDPVNKYQLTPLHYAAMKSNFSALHALIKLKADVDAEDDNKMT 191
Query: 249 ALHWGTVKGSIPVMDLLIKHGSD 271
L V GS ++ LIK S+
Sbjct: 192 PLLLACVHGSQEIIQELIKANSN 214
>Hs18561834 [M] KOG4177 Ankyrin
Length = 568
Score = 55.8 bits (133), Expect = 2e-07
Identities = 46/175 (26%), Positives = 84/175 (47%), Gaps = 8/175 (4%)
Query: 77 YHAACKQGDMKTLREMVESKV-IDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEV 135
+ A K ++ + ++ E KV I++ N+ + + LH+A N LSAV +L A V
Sbjct: 72 FQNAAKSNNLDLMEKLFEKKVNINVVNNMNR----TALHFAVGRNHLSAVDFLLKHKARV 127
Query: 136 NFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYV 195
+ + T +H A+ SG + ++ L+KAGAD + G + LH + S+++ +V Y+
Sbjct: 128 DV-ADKHGLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYL 186
Query: 196 LFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTAL 250
+ + +D++QPD R A + +E L N D ++ L
Sbjct: 187 IQDL--HLKDLNQPDEKGRKPFLLAAERGHVEMIEKLTFLNLHTSEKDKIQWSTL 239
Score = 53.9 bits (128), Expect = 9e-07
Identities = 35/98 (35%), Positives = 52/98 (52%), Gaps = 3/98 (3%)
Query: 95 SKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSG 154
S+ +DL +PKE S LH INN ++ V L A +++ + TPLH A+ G
Sbjct: 334 SENVDLHQKVEPKE--SPLHLVVINNHITVVNSLLSAQHDIDILN-QKQQTPLHVAADRG 390
Query: 155 LVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLV 192
V +V+ LLKAG D D QG L + S++ ++V
Sbjct: 391 NVELVETLLKAGCDLKAVDKQGKTALAVASRSNHSLVV 428
Score = 50.4 bits (119), Expect = 1e-05
Identities = 36/155 (23%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 150 ASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQP 209
A+KS + ++++L + + N+ ++ LH +V +++ V ++L K VD
Sbjct: 75 AAKSNNLDLMEKLFEKKVNINVVNNMNRTALHFAVGRNHLSAVDFLL----KHKARVDVA 130
Query: 210 DPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIK-- 267
D H T + A + + L+K AD + + G +ALH+ T + +++ LI+
Sbjct: 131 DKHGLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYLIQDL 190
Query: 268 HGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKN 302
H D Q G+ F + E + +E + N
Sbjct: 191 HLKDLNQPDEKGRKPFLLAAERGHVEMIEKLTFLN 225
>CE00274 [T] KOG1217 Fibrillins and related proteins containing Ca2+-binding
EGF-like domains
Length = 1429
Score = 55.5 bits (132), Expect = 3e-07
Identities = 57/219 (26%), Positives = 97/219 (44%), Gaps = 25/219 (11%)
Query: 102 NDYDPKERVSGLHWACINNR--------LSAVKYLAGAGAEVNFKGGELDATPLHWASKS 153
N DP+ + LHW N+ + K AGA+VN + + TPL A +
Sbjct: 1046 NIIDPRHNRTVLHWIASNSSAEKSEDLIVHEAKECIAAGADVNAMDCD-ENTPLMLAVLA 1104
Query: 154 GLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQ 213
+V L+KAGADP I + + LH + + + +++Y+L K D+++ D +
Sbjct: 1105 RRRRLVAYLMKAGADPTIYNKSERSALHQAAANRDFGMMVYML-NSTKLKGDIEELDRNG 1163
Query: 214 RTALQWATYQ-------ADALTVENLLKFNADVKNADDA----GFTALHWGTVKGSIPVM 262
TAL + + L VE K + D D+ G TALH+ ++P++
Sbjct: 1164 MTALMIVAHNEGRDQVASAKLLVEKGAKVDYDGAARKDSEKYKGRTALHYAAQVSNMPIV 1223
Query: 263 DLLI-KHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLY 300
L+ + GS+ + DGK + + G +E +Y
Sbjct: 1224 KYLVGEKGSNKDKQDEDGKTPIMLAAQ---EGRIEVVMY 1259
>7301583 [R] KOG0504 FOG: Ankyrin repeat
Length = 1162
Score = 55.1 bits (131), Expect = 4e-07
Identities = 52/171 (30%), Positives = 71/171 (41%), Gaps = 19/171 (11%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH A I L+ V L A+VN E + +HWA+ G V + +L AGA
Sbjct: 75 LHLAVIQGNLAMVNLLLANKADVNAVDNEGHSV-VHWATVCGEVESLRAVLAAGASVAKP 133
Query: 173 DSQGYNLLH-----------------TSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRT 215
D+ G LH +S SS + L I + + + VD D R
Sbjct: 134 DANGGTPLHYAAQMCGASKQDSKQQASSSNSSRLSLEILGIL-LSHPQSSVDVQDKDGRQ 192
Query: 216 ALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLI 266
L WA A V L+K A V+++D G TALH +G +D LI
Sbjct: 193 PLLWAASAGSAKAVIALVKAGARVESSDKDGLTALHCAGSRGHTECIDTLI 243
>Hs7656961 [R] KOG0504 FOG: Ankyrin repeat
Length = 319
Score = 54.7 bits (130), Expect = 5e-07
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 10/166 (6%)
Query: 92 MVESKVIDLSN-DYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWA 150
+VE + D +N D + + + LH AC+ L+ V+ L AGA++ F+ L++T +HWA
Sbjct: 135 VVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRD-MLESTAIHWA 193
Query: 151 SKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPD 210
S+ G + ++ LL GA + D LH +V + + + ++ + D++ D
Sbjct: 194 SRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEH----LIACEADLNAKD 249
Query: 211 PHQRTALQWATYQADALTVENLLKFNADVKNADDAGFT----ALHW 252
T L A + L+ + AD+ + AG T LHW
Sbjct: 250 REGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHW 295
>Hs13129098 [R] KOG0504 FOG: Ankyrin repeat
Length = 288
Score = 54.7 bits (130), Expect = 5e-07
Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 6/138 (4%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH AC+ + V+ L GAEVN G + T LH+A++ V+ LL+ GA+PN
Sbjct: 57 LHCACMVSDADCVELLLEKGAEVNALDG-YNRTALHYAAEKDEA-CVEVLLEYGANPNAL 114
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
D LH + F +N V +L + V+ D + T L WA + + +V L
Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALL----ESGASVNALDYNNDTPLSWAAMKGNLESVSIL 170
Query: 233 LKFNADVKNADDAGFTAL 250
L + A+V+ + G T +
Sbjct: 171 LDYGAEVRVINLIGQTPI 188
Score = 53.9 bits (128), Expect = 9e-07
Identities = 40/147 (27%), Positives = 68/147 (46%), Gaps = 7/147 (4%)
Query: 125 VKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSV 184
V+ L GA+VN G L PLH A V+ LL+ GA+ N D LH +
Sbjct: 37 VEDLIRGGADVNCTHGTLK--PLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAA 94
Query: 185 FSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADD 244
+ + +++ + + D ++ T L WA ++ +A V LL+ A V D
Sbjct: 95 EKDEACVEV-----LLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDY 149
Query: 245 AGFTALHWGTVKGSIPVMDLLIKHGSD 271
T L W +KG++ + +L+ +G++
Sbjct: 150 NNDTPLSWAAMKGNLESVSILLDYGAE 176
>At3g04710_1 [R] KOG0504 FOG: Ankyrin repeat
Length = 333
Score = 54.7 bits (130), Expect = 5e-07
Identities = 55/212 (25%), Positives = 94/212 (43%), Gaps = 23/212 (10%)
Query: 70 KDPILERYHAACKQGDMKTLREMVE--------SKVIDLSNDYDPKERVSGLHWACINNR 121
++ + + +AAC G+++ L+ + + +K ++ D + + LH+A +
Sbjct: 12 REKVQQILNAACT-GNLEFLKNVAKQLDEGKDLTKTVESIKDANKR---GALHFAAREGQ 67
Query: 122 LSAVKYLAGA---GAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYN 178
+YL A+ + G+ TPL A++ G + V LL+ GADPNI G
Sbjct: 68 TEICRYLLEELKLNADAKDETGD---TPLVHAARQGQIETVKYLLEQGADPNIASELGAT 124
Query: 179 LLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNAD 238
LH + + I L+ +L V VD + T L WA VE LL+ NA+
Sbjct: 125 ALHHAAGTGEIELLKELLSRGV----PVDS-ESESGTPLIWAAGHDQKNAVEVLLEHNAN 179
Query: 239 VKNADDAGFTALHWGTVKGSIPVMDLLIKHGS 270
+ T L GS+ ++LL+K G+
Sbjct: 180 PNAETEDNITPLLSAVAAGSLSCLELLVKAGA 211
Score = 50.8 bits (120), Expect = 7e-06
Identities = 37/103 (35%), Positives = 55/103 (52%), Gaps = 5/103 (4%)
Query: 105 DPKERVSGLHWACINNRLSAVKYLAGAGAEVN-FKGGELDATPLHWASKSGLVYIVDELL 163
+ ++ ++ L A LS ++ L AGA+ N F GG ATPLH A+ G + +++ LL
Sbjct: 183 ETEDNITPLLSAVAAGSLSCLELLVKAGAKANVFAGG---ATPLHIAADIGNLELINCLL 239
Query: 164 KAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDV 206
KAGADPN D +G L + N V+ +LF + E V
Sbjct: 240 KAGADPNQKDEEGNRPLEVAAARDN-RKVVEILFPLTTKPETV 281
>YIL112w [R] KOG0504 FOG: Ankyrin repeat
Length = 1083
Score = 54.3 bits (129), Expect = 7e-07
Identities = 37/102 (36%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Query: 76 RYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEV 135
R AC +G +++M+E D+ ND D + LH A + + V+ L GA+V
Sbjct: 333 RLQIACDKGKYDVVKKMIEEGGYDI-NDQDNAGNTA-LHEAALQGHIEIVELLIENGADV 390
Query: 136 NFKGGELDA-TPLHWASKSGLVYIVDELLKAGADPNITDSQG 176
N K E+ TPL AS +G + +V LLK GADP I +++G
Sbjct: 391 NIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKG 432
>CE27598 [R] KOG0504 FOG: Ankyrin repeat
Length = 840
Score = 53.5 bits (127), Expect = 1e-06
Identities = 46/172 (26%), Positives = 71/172 (40%), Gaps = 11/172 (6%)
Query: 107 KERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAG 166
+E+ +H+A + L +K + A + TPL A +G + D L G
Sbjct: 34 EEKKVAIHYAAASGDLKTLKLVFLADRSLLDVKDATGQTPLLCALMAGKIENADFLANTG 93
Query: 167 ADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQR-TALQWATYQAD 225
AD D QG N LH +V + L + ++ +V+ D +QR T L +AT D
Sbjct: 94 ADAECHDEQGRNALHWAVVCGQ----LDSLNWAINKNVEVNAKDQYQRCTPLHYATCSED 149
Query: 226 ------ALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
+ LLK AD D T +HW + G++ + L G D
Sbjct: 150 IAPEVSQAILITLLKHGADPNAIDADDRTPIHWCSSNGNLEAIKALYNSGGD 201
Score = 51.6 bits (122), Expect = 4e-06
Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 9/177 (5%)
Query: 102 NDYDPKERVSGLHWACINNRLSA------VKYLAGAGAEVNFKGGELDATPLHWASKSGL 155
N D +R + LH+A + ++ + L GA+ N + D TP+HW S +G
Sbjct: 130 NAKDQYQRCTPLHYATCSEDIAPEVSQAILITLLKHGADPNAIDAD-DRTPIHWCSSNGN 188
Query: 156 VYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRT 215
+ + L +G D D + +LH + ++ + L V K +D+ D T
Sbjct: 189 LEAIKALYNSGGDLLCRDKEHLTILHCAASHGYHEVIEFALKHV--NKPFIDEIDRAGHT 246
Query: 216 ALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDF 272
AL +A + LL+ NA+ + D TA H KG + ++ LL + + F
Sbjct: 247 ALFYAISFGHYESALKLLQNNANPNHQDQRLATAAHSAASKGQMRMLKLLKQFNASF 303
>Hs22047178 [R] KOG0504 FOG: Ankyrin repeat
Length = 264
Score = 53.1 bits (126), Expect = 2e-06
Identities = 57/220 (25%), Positives = 90/220 (40%), Gaps = 13/220 (5%)
Query: 70 KDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLA 129
+D L + H A +GD + + + DL + D K+R LH C + R+ V L
Sbjct: 31 RDWELRKIHRAAIKGDAAEVEHCLTRRFRDL-DARDRKDRTV-LHLTCAHGRVEVVTLLL 88
Query: 130 GAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNI 189
++N L+ TPL A LL+ GA+PNI D LH +V++
Sbjct: 89 SRRCQINIYD-RLNRTPLMKAVHCQEEACAIILLEHGANPNIKDIYSNTALHYAVYNKGT 147
Query: 190 MLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTA 249
L +L +++ + T L +A VE LLK A++ D+ TA
Sbjct: 148 SLAEKLL----SHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQANLHAIDNFRRTA 203
Query: 250 LHWGTVKGSIPVMDLLIKHGSDFF------QTTNDGKNCF 283
L S ++ LL++ + F QT D C+
Sbjct: 204 LMLAVQHNSSSIVSLLLQQNINIFSQDLFGQTAEDYAVCY 243
>Hs21450703 [R] KOG0504 FOG: Ankyrin repeat
Length = 258
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/83 (38%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 102 NDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDE 161
N +D R + LHWAC+ V L AGA V+ + LD TP+ WA + G + I+ +
Sbjct: 138 NAHDKLHRTA-LHWACLKGHSQLVNKLLVAGATVDARD-LLDRTPVFWACRGGHLVILKQ 195
Query: 162 LLKAGADPNITDSQGYNLLHTSV 184
LL GA N D G LH +V
Sbjct: 196 LLNQGARVNARDKIGSTPLHVAV 218
>Hs14149971 [R] KOG0504 FOG: Ankyrin repeat
Length = 823
Score = 53.1 bits (126), Expect = 2e-06
Identities = 54/212 (25%), Positives = 86/212 (40%), Gaps = 7/212 (3%)
Query: 70 KDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLA 129
+D L++ H A +GD + + + DL D K+ + LH AC + + V L
Sbjct: 30 RDSELQKIHRAAVKGDAAEVERCLARRSGDL--DALDKQHRTALHLACASGHVQVVTLLV 87
Query: 130 GAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNI 189
+++ E + TPL A LL+ GA+PN D G LH +V+S +
Sbjct: 88 NRKCQIDVCDKE-NRTPLIQAVHCQEEACAVILLEHGANPNFKDIYGNTALHYAVYSEST 146
Query: 190 MLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTA 249
L +L ++ D T L +A VE LLK A D +A
Sbjct: 147 SLAEKLL----SHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSA 202
Query: 250 LHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKN 281
L S ++++L+K D F G++
Sbjct: 203 LMLAVYYDSPGIVNILLKQNIDVFAQDMCGRD 234
>At5g60070 [R] KOG0504 FOG: Ankyrin repeat
Length = 548
Score = 53.1 bits (126), Expect = 2e-06
Identities = 55/203 (27%), Positives = 86/203 (42%), Gaps = 20/203 (9%)
Query: 77 YHAACKQGDMKTLREMVE-----SKVIDLSNDYDPKERVSGLHWACINNRLSAVKY-LAG 130
+H A KQG++ LR ++E S +DLSN + LH A + V+Y L
Sbjct: 112 FHIAAKQGELDVLRVLMEEHPELSMTVDLSN-------TTALHTAAAQGHVEVVEYLLEA 164
Query: 131 AGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGAD-PNITDSQGYNLLHTSVFSSNI 189
AG+ + T LH A+++G +V ++ D TD +G LH +V +I
Sbjct: 165 AGSSLAAIAKSNGKTALHSAARNGHAEVVKAIVAVEPDTATRTDKKGQTPLHMAVKGQSI 224
Query: 190 MLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFN---ADVKNADDAG 246
+V+ ++ + ++ D TAL AT + VE LL N K + AG
Sbjct: 225 DVVVELM---KGHRSSLNMADSKGNTALHVATRKGRIKIVELLLDNNETSPSTKAINRAG 281
Query: 247 FTALHWGTVKGSIPVMDLLIKHG 269
T L G + +L G
Sbjct: 282 ETPLDTAEKTGHPQIAAVLKTRG 304
>HsM14249476 [R] KOG1311 DHHC-type Zn-finger proteins
Length = 215
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/147 (23%), Positives = 70/147 (46%), Gaps = 11/147 (7%)
Query: 387 ILSGTIAIAFFIWFTKISILTFTEKPVGNIIMLGFFIGLITLFIGLMKSDPGYI---PGT 443
+L+ I + F+ T++ + + + L +G + L++ + DPGY+ P
Sbjct: 19 VLTWGITLVLFLHDTELRQWEEQGELLLPLTFLLLVLGSLLLYLAVSLMDPGYVNVQPQP 78
Query: 444 VDHDKVRET--IKELLSLGKFDAKHFCVHTWIRIPLRSKYDRDSACLISAFDHFCPWVYN 501
+ K +T + + L + C + + PLR+++ R+ + +DH CPW+ N
Sbjct: 79 QEELKEEQTAMVPPAIPLRR------CRYCLVLQPLRARHCRECRRCVRRYDHHCPWMEN 132
Query: 502 QIGLLNHKLFYMFVVLLEISVWWFLPL 528
+G NH LF +++ L + + W L L
Sbjct: 133 CVGERNHPLFVVYLALQLVVLLWGLYL 159
>Hs7662406 [R] KOG0504 FOG: Ankyrin repeat
Length = 692
Score = 52.8 bits (125), Expect = 2e-06
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 4/141 (2%)
Query: 145 TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKE 204
TPLH A+ G + +V LLKAG D ++ D LH + N ++ ++ +G
Sbjct: 44 TPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIH---EGCA 100
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
+D+ D TAL A++ + + + L+K A+V + AG TALH +
Sbjct: 101 -LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRV 159
Query: 265 LIKHGSDFFQTTNDGKNCFTI 285
L+ GS N G C +
Sbjct: 160 LLLAGSRADLKNNAGDTCLHV 180
>Hs21361910 [R] KOG1311 DHHC-type Zn-finger proteins
Length = 267
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/147 (23%), Positives = 70/147 (46%), Gaps = 11/147 (7%)
Query: 387 ILSGTIAIAFFIWFTKISILTFTEKPVGNIIMLGFFIGLITLFIGLMKSDPGYI---PGT 443
+L+ I + F+ T++ + + + L +G + L++ + DPGY+ P
Sbjct: 19 VLTWGITLVLFLHDTELRQWEEQGELLLPLTFLLLVLGSLLLYLAVSLMDPGYVNVQPQP 78
Query: 444 VDHDKVRET--IKELLSLGKFDAKHFCVHTWIRIPLRSKYDRDSACLISAFDHFCPWVYN 501
+ K +T + + L + C + + PLR+++ R+ + +DH CPW+ N
Sbjct: 79 QEELKEEQTAMVPPAIPLRR------CRYCLVLQPLRARHCRECRRCVRRYDHHCPWMEN 132
Query: 502 QIGLLNHKLFYMFVVLLEISVWWFLPL 528
+G NH LF +++ L + + W L L
Sbjct: 133 CVGERNHPLFVVYLALQLVVLLWGLYL 159
>Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1176
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 9/175 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
HAA ++G ++ ++++ + D K++ + L A +NN L +Y+ G V
Sbjct: 656 HAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAG-ADPNITDSQGYNLLHTSVFSSNIMLVIYVL 196
K E +T LH A+K G + +V LL G D N DS G+ T + + I V+
Sbjct: 713 KE-EDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGW----TPIIWAAEHKHIEVI 767
Query: 197 FFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALH 251
++ DV D + L WA++ A E LL D+ + G T LH
Sbjct: 768 RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLH 822
>Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1210
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 9/175 (5%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
HAA ++G ++ ++++ + D K++ + L A +NN L +Y+ G V
Sbjct: 690 HAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAG-ADPNITDSQGYNLLHTSVFSSNIMLVIYVL 196
K E +T LH A+K G + +V LL G D N DS G+ T + + I V+
Sbjct: 747 KE-EDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGW----TPIIWAAEHKHIEVI 801
Query: 197 FFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALH 251
++ DV D + L WA++ A E LL D+ + G T LH
Sbjct: 802 RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLH 856
>Hs16159328 [R] KOG0504 FOG: Ankyrin repeat
Length = 683
Score = 52.8 bits (125), Expect = 2e-06
Identities = 41/167 (24%), Positives = 82/167 (48%), Gaps = 10/167 (5%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH A + +K L +GA+ + K + TPLH+A+ + + ++ L+ GA+ N T
Sbjct: 116 LHAAAAGGNVECIKLLQSSGADFH-KKDKCGRTPLHYAAANCHFHCIETLVTTGANVNET 174
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
D G LH + +S++ +L D E++++ A + +A L +E L
Sbjct: 175 DDWGRTALHYAA-ASDMDRNKTILGNAHDNSEELER-------ARELKEKEA-TLCLEFL 225
Query: 233 LKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDG 279
L+ +A+ D G+ ++H+ G ++LL++ + F+ ++ G
Sbjct: 226 LQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSG 272
>CE23926 [T] KOG4369 RTK signaling protein MASK/UNC-44
Length = 2584
Score = 52.8 bits (125), Expect = 2e-06
Identities = 47/161 (29%), Positives = 71/161 (43%), Gaps = 2/161 (1%)
Query: 111 SGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPN 170
+ L AC R V+ L GA + D TPL AS G + IV+ LL AG++ N
Sbjct: 1290 TALSLACSGGRKDVVELLLAHGANKEHRNVS-DYTPLSLASSGGYIEIVNMLLTAGSEIN 1348
Query: 171 ITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVE 230
+ + S N + G + Q + ++ TAL A++Q V+
Sbjct: 1349 SRTGSKLGISPLMLASMNGHREA-TRVLLEKGSDINAQIETNRNTALTLASFQGRTEVVK 1407
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
LL +NA+V++ G T L G + V +LLI G+D
Sbjct: 1408 LLLAYNANVEHRAKTGLTPLMECASGGYVDVGNLLIAAGAD 1448
>CE19676 [R] KOG0504 FOG: Ankyrin repeat
Length = 597
Score = 52.8 bits (125), Expect = 2e-06
Identities = 50/203 (24%), Positives = 90/203 (43%), Gaps = 13/203 (6%)
Query: 77 YHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGL---HWACINNRLSAVKYLAGAGA 133
+H A K G +L+ ++ D+ N+ + GL H A AV YL GA
Sbjct: 178 FHVAAKNGQSFSLKLLLSVIPPDIKNEVINVQNTHGLTALHVAIRTGDPDAVHYLMNHGA 237
Query: 134 EVNFKGGELDATPLHWASKSGLVYIVDELLKAGA----DPNITDSQGYNLLHTSVFSSNI 189
+++ +T LH+ + I E+L+ D N +S+G+ +H +V +
Sbjct: 238 KIDISDNH-GSTALHYLGDAYNESIFKEILEPSRGQRFDVNQLNSEGFAPIHVAVRRLKL 296
Query: 190 MLVIYVLFFVVDGKEDVDQPDPHQ-RTALQWATYQADALTVENLLKFNADVKNADDAGFT 248
L+ +++ +D D + R AL A D T++ L++ + D++G T
Sbjct: 297 SLIE----MLIEAGALIDFLDTEKKRNALMHAIEMNDFETIQLLVERGSGTNIEDESGET 352
Query: 249 ALHWGTVKGSIPVMDLLIKHGSD 271
AL + PV+ LL+ +G+D
Sbjct: 353 ALSLAVKNVNYPVIGLLLDNGAD 375
>CE06305 [T] KOG4369 RTK signaling protein MASK/UNC-44
Length = 2606
Score = 52.8 bits (125), Expect = 2e-06
Identities = 47/161 (29%), Positives = 71/161 (43%), Gaps = 2/161 (1%)
Query: 111 SGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPN 170
+ L AC R V+ L GA + D TPL AS G + IV+ LL AG++ N
Sbjct: 1290 TALSLACSGGRKDVVELLLAHGANKEHRNVS-DYTPLSLASSGGYIEIVNMLLTAGSEIN 1348
Query: 171 ITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVE 230
+ + S N + G + Q + ++ TAL A++Q V+
Sbjct: 1349 SRTGSKLGISPLMLASMNGHREA-TRVLLEKGSDINAQIETNRNTALTLASFQGRTEVVK 1407
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
LL +NA+V++ G T L G + V +LLI G+D
Sbjct: 1408 LLLAYNANVEHRAKTGLTPLMECASGGYVDVGNLLIAAGAD 1448
>Hs16076877 [R] KOG0504 FOG: Ankyrin repeat
Length = 1101
Score = 52.0 bits (123), Expect = 3e-06
Identities = 48/169 (28%), Positives = 68/169 (39%), Gaps = 5/169 (2%)
Query: 102 NDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDE 161
N +D + L A +L + L GA V + A PL + G IVD
Sbjct: 128 NSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVA-QPNRRGAVPLFSTVRQGHWQIVDL 186
Query: 162 LLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWAT 221
LL GAD N+ D QG L + ++ V ++L G + D TAL WA
Sbjct: 187 LLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLL---AQGAS-IALMDKEGLTALSWAC 242
Query: 222 YQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGS 270
+ V +L+ A +AD G T L G V+ L+ HG+
Sbjct: 243 LKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGA 291
>Hs14150169 [I] KOG0817 Acyl-CoA-binding protein
Length = 282
Score = 52.0 bits (123), Expect = 3e-06
Identities = 32/96 (33%), Positives = 52/96 (53%), Gaps = 3/96 (3%)
Query: 81 CKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGG 140
C++ ++ + + ++SK +D+ N D + R LHWAC V L A++N +
Sbjct: 166 CRENNIDHITKAIKSKNVDV-NVKDEEGRAL-LHWACDRGHKELVTVLLQHRADINCQDN 223
Query: 141 ELDATPLHWASKSGLVYIVDELLKAGADPNITDSQG 176
E T LH+AS + IV+ LL++GADP + D G
Sbjct: 224 E-GQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258
>Hs13375989 [R] KOG0504 FOG: Ankyrin repeat
Length = 278
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/213 (26%), Positives = 97/213 (44%), Gaps = 14/213 (6%)
Query: 68 VEKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKY 127
VE+ P+ H A ++G+ L++++ES D ++ LH A + + V+
Sbjct: 18 VERTPV----HEAAQRGESLQLQQLIESGACVNQVTVDS---ITPLHAASLQGQARCVQL 70
Query: 128 LAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSS 187
L AGA+V+ + + +TPL A SG + V L GA N + LH + S
Sbjct: 71 LLAAGAQVDARNID-GSTPLCDACASGSIECVKLSLSYGAKVN-PPLYTASPLHEACMSG 128
Query: 188 NIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGF 247
+ V ++D +++ D H T L A + V+ LL A+V NA
Sbjct: 129 SSECVR----LLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANV-NAAKLHE 183
Query: 248 TALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGK 280
TALH ++ ++++LI+ G + + N GK
Sbjct: 184 TALHHAAKVKNVDLIEMLIEFGGNIYARDNRGK 216
>7291279 [R] KOG0502 Integral membrane ankyrin-repeat protein Kidins220
(protein kinase D substrate)
Length = 1498
Score = 52.0 bits (123), Expect = 3e-06
Identities = 52/189 (27%), Positives = 89/189 (46%), Gaps = 11/189 (5%)
Query: 85 DMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSA-VKYLAGAGAEVNFKGGELD 143
D+ LR +++S+ + + D E + + L+A V+ GA+V + +LD
Sbjct: 39 DISGLRAILDSRHLTID---DRDENATTVLMVVAGRGLTAFVREFLARGADVQAE--DLD 93
Query: 144 A-TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDG 202
T L AS++G + +V LL GA+ D G+ L + + + LV +L DG
Sbjct: 94 NWTALLCASRNGHLDVVQLLLDHGAEVEHRDMGGWTSLMWAAYRGHTELVRLLLDKGADG 153
Query: 203 KEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVM 262
+ + AL WA + VE L++ A V D G TAL W +G++ ++
Sbjct: 154 NAHGN----YHLGALLWAAGRGYKDIVELLVQRGAKVNVGDKYGTTALVWACRRGNVEIV 209
Query: 263 DLLIKHGSD 271
D L+K G++
Sbjct: 210 DTLLKAGAN 218
>Hs7705831 [R] KOG0504 FOG: Ankyrin repeat
Length = 518
Score = 51.6 bits (122), Expect = 4e-06
Identities = 66/265 (24%), Positives = 117/265 (43%), Gaps = 29/265 (10%)
Query: 80 ACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF-K 138
A ++G++K LR++++ S D +H A +N + ++ L A + N+ K
Sbjct: 17 AAREGNVKVLRKLLKK---GRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 73
Query: 139 GGELDA-TPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
+ LH A+ G IV LL+AGADPN T + L +V + I ++ +L
Sbjct: 74 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLL- 132
Query: 198 FVVDGKEDVDQPDPHQR---TALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGT 254
+ + H +L A++Q +A ++ LL+ A+ + DD G T L
Sbjct: 133 -----QHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAA 187
Query: 255 VKGSIPVMDLLIKHGSDF-FQTTNDGKNCFTIGKE--------LYSIGSLEASLYKNGFD 305
G + + +LI G++ Q + F +E L S G+ + LY N
Sbjct: 188 QYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGA-DPDLYCN--- 243
Query: 306 KNGFPLPQYFSASTG--KMLTFFLP 328
++ + LP + +A G K+L +P
Sbjct: 244 EDSWQLPIHAAAQMGHTKILDLLIP 268
>Hs10190676_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 280
Score = 51.6 bits (122), Expect = 4e-06
Identities = 50/195 (25%), Positives = 82/195 (41%), Gaps = 9/195 (4%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A + GD + R ++E D++ + + +H AC + + + V+ L G +V+
Sbjct: 5 HFAAQNGDESSTRLLLEKNASVNEVDFEGR---TPMHVACQHGQENIVRILLRRGVDVSL 61
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKA-GADPNITDSQGYNLLHTSVFSSNIMLVIYVL 196
+G + PLH+A+ G + IV L K G N G LH + + V
Sbjct: 62 QGKDA-WLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYR----VA 116
Query: 197 FFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVK 256
++D DV+ +T L A T LL A K G+TALH
Sbjct: 117 RILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARN 176
Query: 257 GSIPVMDLLIKHGSD 271
G + + LL++ +D
Sbjct: 177 GHLATVKLLVEEKAD 191
Score = 51.6 bits (122), Expect = 4e-06
Identities = 46/159 (28%), Positives = 70/159 (43%), Gaps = 8/159 (5%)
Query: 113 LHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNIT 172
LH A + L ++VN L TPLH A+++G LL GA
Sbjct: 104 LHLAAQRGHYRVARILIDLCSDVNVCS-LLAQTPLHVAAETGHTSTARLLLHRGAGKKAV 162
Query: 173 DSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENL 232
S GY LH + + ++ V +V+ K DV P +TAL A + VE L
Sbjct: 163 TSDGYTALHLAARNGHLATV----KLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEEL 218
Query: 233 LKFNADVKNA-DDAGFTALHWGTVKGSIPVMDLLIKHGS 270
+ +ADV + D+ G +ALH ++ L++HG+
Sbjct: 219 V--SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 255
>Hs22054847_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 324
Score = 51.2 bits (121), Expect = 6e-06
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 5/161 (3%)
Query: 111 SGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPN 170
+ LH AC+N+ + + LA ++ + E + TPL A + + L+ +G PN
Sbjct: 1 TALHGACVNSHVEVITLLADRKCRLDVRDSE-NRTPLMKALQCWREAYANILVDSGPSPN 59
Query: 171 ITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVE 230
I D G LH +V+S N+ +V +L D+ + T L + VE
Sbjct: 60 IVDVYGNMALHYAVYSENLSVVAKLL----SRGADIQVKNKACLTPLLLVITKRSEEIVE 115
Query: 231 NLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSD 271
L+ NA D TAL GS+ + +L++ D
Sbjct: 116 FLVTKNASANAVDKFKCTALMLAVCHGSLERVSILLQQDID 156
>Hs20472035 [R] KOG0504 FOG: Ankyrin repeat
Length = 361
Score = 50.8 bits (120), Expect = 7e-06
Identities = 55/197 (27%), Positives = 88/197 (43%), Gaps = 12/197 (6%)
Query: 78 HAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNF 137
H A + G L + E+ +D+ +R LH A V+YL G GA V+
Sbjct: 42 HCAARHGHRDVLAYLAEAWGMDIEATNRDYKRP--LHEAASMGHRDCVRYLLGRGAAVDC 99
Query: 138 KGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLF 197
+ D TPL A + ++ EL++ GA+P + + G+N H + + +++ Y+L
Sbjct: 100 LK-KADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLL- 157
Query: 198 FVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLK---FNADVKNADDAGFTALHWGT 254
V G + +RT L A V+ LLK + D + D+ G TAL
Sbjct: 158 TVCPGAWKTE--SKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYR--DNCGVTALMDAI 213
Query: 255 VKGSIPVMDLLI-KHGS 270
G I V LL+ +HG+
Sbjct: 214 QCGHIDVARLLLDEHGA 230
>Hs18252778 [R] KOG0504 FOG: Ankyrin repeat
Length = 587
Score = 50.8 bits (120), Expect = 7e-06
Identities = 49/204 (24%), Positives = 95/204 (46%), Gaps = 20/204 (9%)
Query: 78 HAACKQGDMKTLREMVESKV-IDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVN 136
H + + D++ ++ +V ++ N Y ++ L A + +L A+++LA GA++N
Sbjct: 195 HESVSRNDLEVMQILVSGGAKVESKNAYG----ITPLFVAAQSGQLEALRFLAKYGADIN 250
Query: 137 FKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVL 196
+ + +A+ L+ A K+ +V+ LL GAD N T+ G LH + N +V +L
Sbjct: 251 TQASD-NASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309
Query: 197 FFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNA---------DDAGF 247
V + + + + L A + +E LL DV +D
Sbjct: 310 --PVTSRTRIRRSGV---SPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRS 364
Query: 248 TALHWGTVKGSIPVMDLLIKHGSD 271
+AL++ V ++ +LL++HG+D
Sbjct: 365 SALYFAVVNNNVYATELLLQHGAD 388
>Hs13249344 [T] KOG1217 Fibrillins and related proteins containing Ca2+-binding
EGF-like domains
Length = 2471
Score = 50.8 bits (120), Expect = 7e-06
Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 3/140 (2%)
Query: 132 GAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIML 191
GA + + LH A++ LL AGAD N D+ G LH +V +++
Sbjct: 1866 GASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAV-AADAQG 1924
Query: 192 VIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALH 251
V +L + + D+D T L A A V L+ ADV DD G +ALH
Sbjct: 1925 VFQIL--IRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALH 1982
Query: 252 WGTVKGSIPVMDLLIKHGSD 271
W ++ LL+K+G++
Sbjct: 1983 WAAAVNNVEATLLLLKNGAN 2002
>CE16523 [R] KOG0504 FOG: Ankyrin repeat
Length = 991
Score = 50.8 bits (120), Expect = 7e-06
Identities = 44/203 (21%), Positives = 84/203 (40%), Gaps = 8/203 (3%)
Query: 80 ACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKG 139
A QG ++ ++ + ++ D+ D + L WA IN V++L G++ K
Sbjct: 634 AASQGQLEAVQFLTKTAKADV--DAIDNNGRTALQWAAINGHPEVVEFLCSVGSDEGHKD 691
Query: 140 GELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFV 199
+ A LH+A V +V L D G + + + + N+ ++ Y++
Sbjct: 692 ND-GAVALHYAVTHDHVELVKHLTNQHT-VEAKDRYGQHPMMIAAANGNLKVLEYLMGI- 748
Query: 200 VDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSI 259
+ ++QPD RTAL A+ A ++ + D D G H + I
Sbjct: 749 ---SDIINQPDHEGRTALSLASMAAHTSIIDLISPRITDWSQRDHDGTPLAHTLILSNLI 805
Query: 260 PVMDLLIKHGSDFFQTTNDGKNC 282
V ++ + HG++ + G+ C
Sbjct: 806 FVAEVYLGHGANSSDSDAHGRTC 828
>At5g40160 [R] KOG0504 FOG: Ankyrin repeat
Length = 315
Score = 50.8 bits (120), Expect = 7e-06
Identities = 35/136 (25%), Positives = 63/136 (45%), Gaps = 6/136 (4%)
Query: 146 PLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGK-E 204
PL + S + ++D L++ G D + D LH ++ ++ ++L + +
Sbjct: 155 PLQTLALSMQIQLMDNLIENGLDIDDVDKDNQTALHKAIIGKKEAVISHLLRKGANPHLQ 214
Query: 205 DVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDL 264
D D P + +A TV+ L K+N DV AD+ G+T LH + + +
Sbjct: 215 DRDGAAP-----IHYAVQVGALQTVKLLFKYNVDVNVADNEGWTPLHIAVQSRNRDITKI 269
Query: 265 LIKHGSDFFQTTNDGK 280
L+ +G+D + T DGK
Sbjct: 270 LLTNGADKTRRTKDGK 285
>At2g03430 [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 247
Score = 50.8 bits (120), Expect = 7e-06
Identities = 52/174 (29%), Positives = 74/174 (41%), Gaps = 19/174 (10%)
Query: 86 MKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFK--GGELD 143
+K L E+K + S D E + LH A V+ L GA+VN K GG
Sbjct: 63 VKLLSSSDEAKTVINSKD---DEGWAPLHSAASIGNAELVEVLLTRGADVNAKNNGGR-- 117
Query: 144 ATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGK 203
T LH+A+ G + I LL GA NITD G LH + + V F+++
Sbjct: 118 -TALHYAASKGRLEIAQLLLTHGAKINITDKVGCTPLHRAASVGK----LEVCEFLIEEG 172
Query: 204 EDVDQPDPHQRTALQWATYQADALTVEN-------LLKFNADVKNADDAGFTAL 250
++D D +TAL + D + L++ ADV D G+T L
Sbjct: 173 AEIDATDKMGQTALMHSVICDDKQLKVSMDQVAFLLIRHGADVDVEDKEGYTVL 226
>CE16688 [R] KOG0504 FOG: Ankyrin repeat
Length = 633
Score = 50.4 bits (119), Expect = 1e-05
Identities = 45/170 (26%), Positives = 72/170 (41%), Gaps = 10/170 (5%)
Query: 107 KERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAG 166
++ ++ LH A L AV+ L G+ V+ E TPLH+A++ G IV LL G
Sbjct: 247 RDGMTALHIAVAARNLEAVQLLIELGSSVDLVDNE-QRTPLHYAAEQGYPEIVKFLLCNG 305
Query: 167 ADPNITDSQGYNLLH-TSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQAD 225
A + D G H + FS + +++ + + D R+ L WA +
Sbjct: 306 ARNSTRDHIGATPAHYAAQFSVECLKILFA------ESKITEVNDNEGRSCLMWAVCAGN 359
Query: 226 ALTVENLLKFNADVKNA--DDAGFTALHWGTVKGSIPVMDLLIKHGSDFF 273
+ L++ K A D G+TALH + G V +L + F
Sbjct: 360 IEVINYLIQREDAPKRAACDKNGYTALHLAAMVGHEKVCKILTNQPTSIF 409
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.140 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,857,365
Number of Sequences: 60738
Number of extensions: 2028467
Number of successful extensions: 7264
Number of sequences better than 1.0e-05: 95
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 6080
Number of HSP's gapped (non-prelim): 543
length of query: 752
length of database: 30,389,216
effective HSP length: 114
effective length of query: 638
effective length of database: 23,465,084
effective search space: 14970723592
effective search space used: 14970723592
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)