ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4411 good O KOG1364 Posttranslational modification, protein turnover, chaperones Predicted ubiquitin regulatory protein, contains UAS and UBX domains
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4411 1512395 1513936 514
(514 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR330w [O] KOG1364 Predicted ubiquitin regulatory protein conta... 469 e-132
SPAC2C4.15c [O] KOG1364 Predicted ubiquitin regulatory protein c... 162 9e-40
Hs22042348 [O] KOG1364 Predicted ubiquitin regulatory protein co... 100 7e-21
At1g14570 [O] KOG1364 Predicted ubiquitin regulatory protein con... 98 3e-20
7296919 [O] KOG1364 Predicted ubiquitin regulatory protein conta... 96 1e-19
>YDR330w [O] KOG1364 Predicted ubiquitin regulatory protein contains UAS and
UBX domains
Length = 500
Score = 469 bits (1208), Expect = e-132
Identities = 255/519 (49%), Positives = 323/519 (62%), Gaps = 32/519 (6%)
Query: 2 ISDEDISTFQGVCGTDNDELSRHFLEMAGGNLETAISLFFEHGGERQLXXXXXXXXXXXX 61
+S+ + F + G D+ ++ F+EMA GNL TAISLFFE+GG L
Sbjct: 1 MSEGKVDEFMAITGADDAAIATQFIEMADGNLNTAISLFFENGGAALLSSNNTPTPSNST 60
Query: 62 XXXXXXXXXXXXXDVEFAEELQRQAYQ----DEDQYRAPDQARHETLVETNVFPSVYGGI 117
D + AE LQR+AYQ D+D R PD+ARHE L ET+ FP YGGI
Sbjct: 61 PMAPTSVDSDA--DAQLAERLQREAYQQQQPDQDYVRPPDEARHEVLTETSGFPISYGGI 118
Query: 118 GGSFEPLRNARDMFDNSRPSGIFNQQLDTDLLRSGRSNNYHRXXXXXXXXXAFTDEENYP 177
GG FEPL DMFD RP IFNQ+LD N + ++EEN
Sbjct: 119 GGRFEPLHRVNDMFDEGRPESIFNQRLD--------DTNTNTYINDNSSDSLDSEEEN-- 168
Query: 178 SXXXXXXXXXXXXXXXXXXXXLREYTKWVKKPKPMSKETRLALLFRPPFDLMAKYDLDTA 237
++EYTK V+KPK +SKE +LALLFRPPF +M+K DLD A
Sbjct: 169 -DDDEYEYVEEPVIELDEDGNIKEYTKLVRKPKTISKEQKLALLFRPPFSIMSKLDLDAA 227
Query: 238 RQKAKKRNKWVMINIQCADIFQCQMLNRDLWSNAGIKSFIKQNFIFLQYQYESRLASAYV 297
+QKA+ + KW+MINIQ + IFQCQ LNRDLWS+ +K+ IK+NF+FLQYQYESR A Y+
Sbjct: 228 KQKARAKQKWIMINIQDSGIFQCQALNRDLWSSRPVKTIIKENFVFLQYQYESRNAQPYL 287
Query: 298 QRYGFNDKEDCPHIAILDPITGERLKFWSREVPTVENFRQELEIFLEEFSLDPTTTNPPV 357
Q Y N+K+D PHIAILDPITGER+K W+R VP E F E+ FL FSLDP NP V
Sbjct: 288 QFYHLNNKDDLPHIAILDPITGERVKQWNRVVPIPEQFISEINEFLASFSLDPKVPNPTV 347
Query: 358 KEPTPKIDPSTLSEEKQLELAIRESLGNQTPTTSDE----TNEKSDQVXXXXXXXXPDGA 413
EP PK+DP+TL+EE+Q+ELAI+ESL N + ++ E T E+ +V PD
Sbjct: 348 NEPLPKVDPTTLTEEQQMELAIKESLNNNSSKSNQEEVPSTGEEQKRV------QEPDP- 400
Query: 414 QWKLFDSIKPIEHAEPDNKPGITTRIQVRSGDGKRLVRRFDAMHDTVRTIYEVIKSHWPE 473
F +I+ H EP NKPGITTRIQ+R+GDG RLVRRF+A+ DTVRTIYEVIK+
Sbjct: 401 ----FSTIEARVHPEPPNKPGITTRIQIRTGDGSRLVRRFNALEDTVRTIYEVIKTEMDG 456
Query: 474 YSQDQFVLTTHTRENLIEKLDESINDAGLKNSSILLEKI 512
++ +F L H RE+LI+KL+ +I DAGLKNSS+LLEK+
Sbjct: 457 FADSRFTLNDHQREDLIDKLNMTIADAGLKNSSLLLEKL 495
>SPAC2C4.15c [O] KOG1364 Predicted ubiquitin regulatory protein contains UAS and
UBX domains
Length = 427
Score = 162 bits (411), Expect = 9e-40
Identities = 104/302 (34%), Positives = 160/302 (52%), Gaps = 20/302 (6%)
Query: 213 SKETRLALLFRPPFDLMAKYDLDTARQKAKKRNKWVMINIQCADIFQCQMLNRDLWSNAG 272
S+ +RLA LFRPP+D+++ LD AR +A + +W+++N+Q + F+CQ+LNRDLW +
Sbjct: 140 SRASRLAKLFRPPYDIISNLSLDEARIEASSQKRWILVNLQTSTSFECQVLNRDLWKDES 199
Query: 273 IKSFIKQNFIFLQYQYESRLASAYVQRYGFNDKEDCPHIAILDPITGERLKFWSREVPTV 332
+K I+ +F+FLQ + + + F PHIAILDP TGER+K WS+ T
Sbjct: 200 VKEVIRAHFLFLQLLDDEEPGMEFKR---FYPVRSTPHIAILDPRTGERVKEWSKSF-TP 255
Query: 333 ENFRQELEIFLEEFSLDPTTTNPPVKEPTPKIDPSTLSEEKQLELAIRESLGNQTPTTSD 392
+F L FLE +LD T+ + +SE++Q+ AI SLGN TT
Sbjct: 256 ADFVIALNDFLEGCTLDETSGRKNPLGAKSQKPVEAMSEDEQMHKAIAASLGNGNSTTES 315
Query: 393 ETNEKSDQVXXXXXXXXPDGAQWKLFDSIKPIEHAEPDNK---PG-ITTRIQVRSGDGKR 448
+ S Q D++ I+ AE D + PG TRIQ+R +G R
Sbjct: 316 QGESSSQQAESHGVAD----------DTVHKIDSAECDAEEPSPGPNVTRIQIRMPNGAR 365
Query: 449 LVRRFDAMHDTVRTIYEVIKSHWPEYSQDQFVLTTHTRENLIEKLDESINDAGLKNSSIL 508
+RRF ++ D V +Y +K + F L T R++L LD +I +AG++N+++
Sbjct: 366 FIRRF-SLTDPVSKVYAYVKGVAEGADKQPFSL-TFQRKSLWTSLDSTIKEAGIQNTALQ 423
Query: 509 LE 510
E
Sbjct: 424 FE 425
>Hs22042348 [O] KOG1364 Predicted ubiquitin regulatory protein contains UAS and
UBX domains
Length = 327
Score = 100 bits (248), Expect = 7e-21
Identities = 65/159 (40%), Positives = 89/159 (55%), Gaps = 14/159 (8%)
Query: 244 RNKWVMINIQCADIFQCQMLNRDLWSNAGIKSFIKQNFIFLQYQYESRLASAYVQRYGFN 303
+NKW+MINIQ F CQ LNRD+WSN +K+ I+++FIF Q ++S Y+Q Y
Sbjct: 2 QNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLG 61
Query: 304 DKEDCPHIAILDPITGERLKFWSREVPTVENFRQELEIFL-EEFSLDPTTTNPPVK--EP 360
D P+++ILDP TG++L W + V +F ++ FL E LD +++PP K
Sbjct: 62 ---DFPYVSILDPRTGQKLVEWHQ--LDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARS 116
Query: 361 TPKIDPSTLSEEKQLELAIRESLGNQTPTTSDETNEKSD 399
ID SE+ QLE AIR SL T D T K D
Sbjct: 117 ESLID---ASEDSQLEAAIRASL---QETHFDSTQTKQD 149
>At1g14570 [O] KOG1364 Predicted ubiquitin regulatory protein contains UAS and
UBX domains
Length = 485
Score = 97.8 bits (242), Expect = 3e-20
Identities = 79/311 (25%), Positives = 134/311 (42%), Gaps = 39/311 (12%)
Query: 218 LALLFRPPFDLMAKYDLDTARQKAKKRNKWVMINIQCADIFQCQMLNRDLWSNAGIKSFI 277
LA L+RPPF LM + + A+ + ++KW+++N+Q F MLNRD W+N + I
Sbjct: 188 LASLYRPPFHLMFQGSFEQAKTTSSSQDKWLLVNLQSTTEFSSHMLNRDTWANDAVSQTI 247
Query: 278 KQNFIFLQYQYESRLASAYVQRYGFNDKEDCPHIAILDPITGERLKFWSREVPTVENFRQ 337
K NFIF Q Y+ V Y E P + ++DP TG+R++ W+ V EN +
Sbjct: 248 KANFIFWQV-YDDTTEGRKVCTY--YKLESIPVVLVIDPTTGQRMRMWTGMVDP-ENLLE 303
Query: 338 ELEIFLE-----------------EFSLDPTTTNPPVKEPTPKIDPSTLSEEKQLELAIR 380
+L F++ FSL P PK D + EE++L+ A+
Sbjct: 304 DLVPFMDGGPREHFASLSKKRPRGSFSLTP--------HSKPKEDVAKDEEEEELQRALA 355
Query: 381 ESLGNQTPTTSDETNEKSDQVXXXXXXXXPDGAQWKLFDSIKPIEHAEPDNKPGITTRIQ 440
SL + S + DQ + + + P+ + R+
Sbjct: 356 ASLEDNNMKESSD-----DQSTIIPEEVAVEAVTSAVLPTFPPLPEEPKGGDRSLQCRVG 410
Query: 441 VRSGDGKRLVRRFDAMHDTVRTIYEVIKSHWPEYSQDQFVLTTHT----RENLIEKLDES 496
+R +G+RL R F DT++ ++ S E + + + T + L + + +
Sbjct: 411 IRLPNGQRLQRNF-LKTDTIQLLWSFCYSQLEESERKKPLKLTQAIPGESKTLEYESNLT 469
Query: 497 INDAGLKNSSI 507
+ +G+ NS I
Sbjct: 470 LEQSGVANSMI 480
>7296919 [O] KOG1364 Predicted ubiquitin regulatory protein contains UAS and
UBX domains
Length = 496
Score = 95.9 bits (237), Expect = 1e-19
Identities = 71/225 (31%), Positives = 107/225 (47%), Gaps = 43/225 (19%)
Query: 216 TRLALLFRPPFDLMAKYDLDTARQKAKKRNKWVMINIQCADIFQCQMLNRDLWSNAGIKS 275
+RL LFRPP D++ L AR+ A KR +W+++N+Q + FQ Q LNRD+WS+ +K
Sbjct: 170 SRLGDLFRPPTDILYSGSLTAAREFATKRQRWLLVNVQ-DENFQSQTLNRDVWSDKELKK 228
Query: 276 FIKQNFIFLQYQYESRLASAYVQRYGFNDKEDCPHIAILDPITGERLKFWSREVPTVENF 335
I++ F F Q ++ +V F P+I ++DP TGE + W P +EN
Sbjct: 229 LIRRQFTFWQVDNDTSEGRRFV---AFYHCATLPYICVIDPRTGEEV--WRSAEPKLENI 283
Query: 336 RQELEIFLEEFS-----------------------LDP----TTTNPPVKEPTPKIDPST 368
+L FL+E DP ++T + P +
Sbjct: 284 LPDLRQFLKEHRDFIQEDAPGTSKRSATYIDDDEVPDPEASCSSTASSKEMPKKRAKVLE 343
Query: 369 LSEEKQLELAIRESLGNQTPTTSDETNEKSDQVXXXXXXXXPDGA 413
L+EE+QLELAI+ S+ N+ E N+K+D PDGA
Sbjct: 344 LTEEEQLELAIKNSI-NENGGGGGEGNQKND---------SPDGA 378
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,348,205
Number of Sequences: 60738
Number of extensions: 1218464
Number of successful extensions: 3249
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3229
Number of HSP's gapped (non-prelim): 9
length of query: 514
length of database: 30,389,216
effective HSP length: 111
effective length of query: 403
effective length of database: 23,647,298
effective search space: 9529861094
effective search space used: 9529861094
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)