ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4428 check: MH T KOG0583 Signal transduction mechanisms Serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4428 1518279 1515724 -852
(852 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR082c [T] KOG0583 Serine/threonine protein kinase 650 0.0
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 176 1e-43
YDR247w [T] KOG0583 Serine/threonine protein kinase 123 1e-27
YPL026c [T] KOG0583 Serine/threonine protein kinase 112 3e-24
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 107 1e-22
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 106 2e-22
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 102 2e-21
At2g26980 [T] KOG0583 Serine/threonine protein kinase 101 4e-21
YGR052w [T] KOG0583 Serine/threonine protein kinase 100 2e-20
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 100 2e-20
7299437 [R] KOG0586 Serine/threonine protein kinase 99 2e-20
At5g07070 [T] KOG0583 Serine/threonine protein kinase 98 5e-20
At1g30270 [T] KOG0583 Serine/threonine protein kinase 98 6e-20
YCL024w [T] KOG0583 Serine/threonine protein kinase 97 8e-20
At4g18700 [T] KOG0583 Serine/threonine protein kinase 97 8e-20
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 97 1e-19
CE27768 [R] KOG0586 Serine/threonine protein kinase 97 1e-19
CE23838 [R] KOG0586 Serine/threonine protein kinase 97 1e-19
At5g58380 [T] KOG0583 Serine/threonine protein kinase 97 1e-19
At5g57630 [T] KOG0583 Serine/threonine protein kinase 97 1e-19
YDR507c [D] KOG0588 Serine/threonine protein kinase 97 1e-19
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 96 2e-19
CE28218 [D] KOG0588 Serine/threonine protein kinase 96 2e-19
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 96 3e-19
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 96 3e-19
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 96 3e-19
At4g24400 [T] KOG0583 Serine/threonine protein kinase 96 3e-19
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 95 4e-19
At5g35410 [T] KOG0583 Serine/threonine protein kinase 95 4e-19
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 95 5e-19
CE21025 [D] KOG0580 Serine/threonine protein kinase 95 5e-19
7302464 [R] KOG0586 Serine/threonine protein kinase 95 5e-19
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 94 7e-19
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 94 9e-19
7302570 [R] KOG0586 Serine/threonine protein kinase 94 9e-19
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 94 1e-18
At2g25090 [T] KOG0583 Serine/threonine protein kinase 94 1e-18
At1g48260 [T] KOG0583 Serine/threonine protein kinase 94 1e-18
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 94 1e-18
At5g45810 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
7297080 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
At1g01140 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 92 3e-18
7290249 [R] KOG0586 Serine/threonine protein kinase 92 3e-18
CE17284 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 92 4e-18
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 92 4e-18
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 92 4e-18
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 92 4e-18
CE00847 [T] KOG0583 Serine/threonine protein kinase 92 4e-18
At1g29230 [T] KOG0583 Serine/threonine protein kinase 92 4e-18
7294217 [D] KOG0588 Serine/threonine protein kinase 92 4e-18
YPL209c [D] KOG0580 Serine/threonine protein kinase 91 6e-18
At5g25110 [T] KOG0583 Serine/threonine protein kinase 91 6e-18
At2g34180 [T] KOG0583 Serine/threonine protein kinase 91 6e-18
At2g30360 [T] KOG0583 Serine/threonine protein kinase 91 6e-18
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 91 6e-18
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 91 8e-18
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 91 8e-18
CE28643 [T] KOG0583 Serine/threonine protein kinase 91 8e-18
CE28479 [T] KOG0583 Serine/threonine protein kinase 91 8e-18
CE07458 [T] KOG0583 Serine/threonine protein kinase 91 8e-18
7303211 [T] KOG4717 Serine/threonine protein kinase 91 8e-18
YMR291w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 91 1e-17
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 91 1e-17
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 91 1e-17
At5g45820 [T] KOG0583 Serine/threonine protein kinase 91 1e-17
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 90 1e-17
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 90 1e-17
CE24761 [D] KOG0580 Serine/threonine protein kinase 90 1e-17
At5g10930 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 90 1e-17
7290150 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 90 2e-17
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 90 2e-17
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 90 2e-17
At4g30960 [T] KOG0583 Serine/threonine protein kinase 90 2e-17
7299438 [R] KOG0586 Serine/threonine protein kinase 90 2e-17
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 2e-17
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 89 3e-17
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 89 3e-17
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 89 3e-17
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 4e-17
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 4e-17
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 88 5e-17
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 88 5e-17
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 5e-17
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 88 5e-17
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 88 6e-17
At3g29160 [T] KOG0583 Serine/threonine protein kinase 88 6e-17
At3g01090 [T] KOG0583 Serine/threonine protein kinase 88 6e-17
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 87 8e-17
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 87 8e-17
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 87 8e-17
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 87 1e-16
At5g01810 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 87 1e-16
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 87 1e-16
YDR477w [T] KOG0583 Serine/threonine protein kinase 87 1e-16
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 87 1e-16
At2g45490 [D] KOG0580 Serine/threonine protein kinase 87 1e-16
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 1e-16
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 2e-16
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 86 2e-16
At3g17510 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 86 2e-16
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 86 2e-16
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 86 2e-16
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 86 2e-16
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 86 2e-16
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 86 2e-16
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 2e-16
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 86 3e-16
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 86 3e-16
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 86 3e-16
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 86 3e-16
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 86 3e-16
CE16081 [T] KOG0583 Serine/threonine protein kinase 86 3e-16
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 86 3e-16
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 85 4e-16
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 85 5e-16
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 85 5e-16
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 5e-16
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 5e-16
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 85 5e-16
YKL101w [D] KOG0588 Serine/threonine protein kinase 84 7e-16
YJL165c [D] KOG0590 Checkpoint kinase and related serine/threoni... 84 7e-16
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 7e-16
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 84 7e-16
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 7e-16
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 84 7e-16
YPL141c [T] KOG0583 Serine/threonine protein kinase 84 9e-16
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 84 9e-16
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 84 9e-16
7296128 [T] KOG0583 Serine/threonine protein kinase 84 9e-16
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 84 1e-15
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 84 1e-15
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 1e-15
CE17343 [T] KOG0583 Serine/threonine protein kinase 84 1e-15
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 1e-15
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 1e-15
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 84 1e-15
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 1e-15
YLR096w [T] KOG0583 Serine/threonine protein kinase 83 2e-15
YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 83 2e-15
At5g39440 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
At3g23000 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
YPL150w [T] KOG0583 Serine/threonine protein kinase 83 2e-15
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 83 2e-15
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 83 2e-15
At4g32830 [D] KOG0580 Serine/threonine protein kinase 83 2e-15
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 83 2e-15
YBL105c [T] KOG0694 Serine/threonine protein kinase 82 3e-15
SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2 82 3e-15
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 82 3e-15
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 82 3e-15
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 82 3e-15
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 3e-15
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 82 3e-15
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 82 3e-15
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
YDR122w [T] KOG0583 Serine/threonine protein kinase 82 3e-15
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 82 3e-15
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 82 3e-15
At5g01820 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 82 5e-15
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 5e-15
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 82 5e-15
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 5e-15
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 82 5e-15
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 81 6e-15
YHR102w [T] KOG0201 Serine/threonine protein kinase 81 6e-15
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 81 6e-15
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 6e-15
At3g15220 [T] KOG0201 Serine/threonine protein kinase 81 6e-15
At1g53165 [T] KOG0201 Serine/threonine protein kinase 81 6e-15
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 6e-15
7299536 [D] KOG0580 Serine/threonine protein kinase 81 6e-15
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 81 8e-15
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 81 8e-15
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 81 8e-15
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 80 1e-14
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 80 1e-14
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 80 1e-14
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 80 1e-14
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 80 1e-14
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
At2g38490 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
YLR113w [T] KOG0660 Mitogen-activated protein kinase 80 1e-14
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 80 1e-14
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 80 1e-14
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
At2g25880 [D] KOG0580 Serine/threonine protein kinase 80 1e-14
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 80 1e-14
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 80 2e-14
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 2e-14
YDR283c [J] KOG1035 eIF-2alpha kinase GCN2 80 2e-14
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 80 2e-14
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 80 2e-14
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 80 2e-14
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 2e-14
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 80 2e-14
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 80 2e-14
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 80 2e-14
YOR267c [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 2e-14
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 79 2e-14
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 79 2e-14
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 79 2e-14
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 79 3e-14
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 79 3e-14
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 3e-14
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 3e-14
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 79 3e-14
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 79 3e-14
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 79 3e-14
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
YOR233w [T] KOG0583 Serine/threonine protein kinase 79 4e-14
YKL168c [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 4e-14
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 79 4e-14
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 79 4e-14
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 4e-14
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 4e-14
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 79 4e-14
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 78 5e-14
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 78 5e-14
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 5e-14
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 5e-14
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 78 7e-14
7300098 [T] KOG4250 TANK binding protein kinase TBK1 78 7e-14
7297611 [T] KOG0614 cGMP-dependent protein kinase 78 7e-14
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 78 7e-14
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 77 9e-14
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 77 9e-14
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 77 9e-14
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 77 1e-13
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 77 1e-13
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 1e-13
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
CE18454 [T] KOG4717 Serine/threonine protein kinase 77 1e-13
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 77 1e-13
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 77 1e-13
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 77 1e-13
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 77 1e-13
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 76 2e-13
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 76 2e-13
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 76 2e-13
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 76 2e-13
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 76 2e-13
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 76 2e-13
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 76 2e-13
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
7290147 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 76 2e-13
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 76 2e-13
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 76 2e-13
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 76 2e-13
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 76 2e-13
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 76 2e-13
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 75 3e-13
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 75 3e-13
SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/thr... 75 3e-13
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 75 3e-13
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 75 3e-13
Hs20128768 [OUT] KOG0595 Serine/threonine-protein kinase involve... 75 3e-13
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 75 3e-13
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 75 3e-13
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 75 3e-13
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 75 3e-13
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 75 3e-13
At4g14580 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 75 3e-13
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 75 3e-13
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
7300224 [T] KOG0201 Serine/threonine protein kinase 75 3e-13
7299793 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
7295638 [T] KOG0603 Ribosomal protein S6 kinase 75 3e-13
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 75 4e-13
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 75 4e-13
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 4e-13
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 4e-13
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 75 4e-13
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 75 4e-13
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 75 4e-13
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 75 6e-13
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 75 6e-13
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 75 6e-13
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 75 6e-13
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 75 6e-13
Hs4507361 [T] KOG0192 Tyrosine kinase specific for activated (GT... 75 6e-13
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 75 6e-13
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 6e-13
Hs21735566 [T] KOG0192 Tyrosine kinase specific for activated (G... 75 6e-13
Hs21735564 [T] KOG0192 Tyrosine kinase specific for activated (G... 75 6e-13
Hs21735562 [T] KOG0192 Tyrosine kinase specific for activated (G... 75 6e-13
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 75 6e-13
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 75 6e-13
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 75 6e-13
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 75 6e-13
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 6e-13
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 75 6e-13
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 75 6e-13
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 75 6e-13
YDL214c [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 7e-13
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 74 7e-13
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 74 7e-13
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 74 7e-13
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 74 7e-13
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 74 7e-13
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 74 7e-13
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 74 7e-13
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 74 7e-13
7300413 [T] KOG0583 Serine/threonine protein kinase 74 7e-13
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 74 7e-13
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 74 9e-13
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 74 9e-13
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 74 9e-13
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 74 9e-13
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 74 9e-13
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 9e-13
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 9e-13
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 9e-13
7297776 [D] KOG0580 Serine/threonine protein kinase 74 9e-13
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 74 1e-12
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 74 1e-12
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 74 1e-12
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 74 1e-12
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 74 1e-12
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 74 1e-12
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 74 1e-12
Hs11140819 [T] KOG1151 Tousled-like protein kinase 74 1e-12
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 74 1e-12
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 74 1e-12
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 74 1e-12
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 74 1e-12
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 74 1e-12
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 74 1e-12
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 74 1e-12
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 74 1e-12
At3g50730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 1e-12
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 1e-12
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 74 1e-12
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 73 2e-12
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 73 2e-12
Hs4506539 [T] KOG0192 Tyrosine kinase specific for activated (GT... 73 2e-12
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 73 2e-12
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 73 2e-12
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 73 2e-12
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 73 2e-12
CE23205 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 73 2e-12
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 2e-12
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 73 2e-12
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 73 2e-12
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 73 2e-12
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 73 2e-12
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 73 2e-12
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 2e-12
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 73 2e-12
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 73 2e-12
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 2e-12
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 2e-12
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 2e-12
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 73 2e-12
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 73 2e-12
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 73 2e-12
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 73 2e-12
At3g04810 [R] KOG0589 Serine/threonine protein kinase 73 2e-12
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 73 2e-12
At1g54510 [R] KOG0589 Serine/threonine protein kinase 73 2e-12
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 2e-12
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 73 2e-12
7295585 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 73 2e-12
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 73 2e-12
SPBC6B1.02 [T] KOG1989 ARK protein kinase family 72 3e-12
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 72 3e-12
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 72 3e-12
Hs22068996 [T] KOG1345 Serine/threonine kinase 72 3e-12
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 3e-12
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 3e-12
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 72 3e-12
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 3e-12
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 72 3e-12
At5g28290 [R] KOG0589 Serine/threonine protein kinase 72 3e-12
At5g23170 [T] KOG1187 Serine/threonine protein kinase 72 3e-12
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 72 3e-12
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 72 3e-12
YDL025c [D] KOG0590 Checkpoint kinase and related serine/threoni... 72 4e-12
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 72 4e-12
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 72 4e-12
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 72 4e-12
Hs22055520 [R] KOG0584 Serine/threonine protein kinase 72 4e-12
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 72 4e-12
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 72 4e-12
CE28674 [T] KOG0201 Serine/threonine protein kinase 72 4e-12
CE24994 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 72 4e-12
CE07510 [T] KOG0201 Serine/threonine protein kinase 72 4e-12
7293601 [T] KOG0577 Serine/threonine protein kinase 72 4e-12
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 72 4e-12
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 72 5e-12
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 72 5e-12
Hs7019547 [T] KOG4250 TANK binding protein kinase TBK1 72 5e-12
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 72 5e-12
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 72 5e-12
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 72 5e-12
CE18366 [T] KOG0583 Serine/threonine protein kinase 72 5e-12
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 72 5e-12
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 72 5e-12
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 72 5e-12
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 72 5e-12
YNL183c [D] KOG0590 Checkpoint kinase and related serine/threoni... 71 6e-12
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 71 6e-12
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 71 6e-12
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 71 6e-12
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 71 6e-12
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 71 6e-12
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
Hs19923134 [T] KOG4250 TANK binding protein kinase TBK1 71 6e-12
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 71 6e-12
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 71 6e-12
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 71 6e-12
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 71 6e-12
7296166 [T] KOG0614 cGMP-dependent protein kinase 71 6e-12
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 71 6e-12
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 8e-12
SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/thr... 71 8e-12
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 8e-12
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 71 8e-12
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 71 8e-12
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 71 8e-12
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 8e-12
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 8e-12
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 71 8e-12
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 71 8e-12
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 71 8e-12
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 71 8e-12
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 71 8e-12
CE20717 [T] KOG0583 Serine/threonine protein kinase 71 8e-12
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 71 8e-12
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 71 8e-12
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 71 8e-12
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 71 8e-12
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 71 8e-12
7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 71 8e-12
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 70 1e-11
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 70 1e-11
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 70 1e-11
Hs20553830 [J] KOG1035 eIF-2alpha kinase GCN2 70 1e-11
Hs12711660 [R] KOG0584 Serine/threonine protein kinase 70 1e-11
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 70 1e-11
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 70 1e-11
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 70 1e-11
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 70 1e-11
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 70 1e-11
CE02604 [T] KOG0695 Serine/threonine protein kinase 70 1e-11
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 70 1e-11
7296749 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 70 1e-11
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 70 1e-11
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 70 1e-11
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 70 1e-11
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 70 1e-11
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 70 1e-11
At5g20930 [T] KOG1151 Tousled-like protein kinase 70 1e-11
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
At3g50720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 1e-11
>YHR082c [T] KOG0583 Serine/threonine protein kinase
Length = 1029
Score = 650 bits (1678), Expect = 0.0
Identities = 435/1055 (41%), Positives = 543/1055 (51%), Gaps = 234/1055 (22%)
Query: 1 MTLDYEVYKEGGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDD----- 55
MTLDYE+YKEGG+L +RY+ IEDISEGSYGYVSLA D + K+LVAVKYIFK EDD
Sbjct: 1 MTLDYEIYKEGGILNNRYQKIEDISEGSYGYVSLAKDVREKRLVAVKYIFKLEDDGQYDG 60
Query: 56 ----------KGNDTKDGVMVIGDEKDDETNNTVN---SSQEKKQRLLKHQKSLISDKVL 102
D + V D ++E N + SS+EKK L KH+KSLIS KV
Sbjct: 61 PQDDENDCDSSDCDDDEDTKVDTDRHENENGNASSNNGSSREKKHNLYKHKKSLISSKVK 120
Query: 103 SRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDSYIIMEYCSGGDLYEAIKDDMVPRK 162
SR SNN+C EA+YEVDIQTKIG+H+NI L DFFDSYIIMEYCSGGDLYEAIK D VP+K
Sbjct: 121 SRLSNNICLEAMYEVDIQTKIGRHQNIAALLDFFDSYIIMEYCSGGDLYEAIKADAVPKK 180
Query: 163 TKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG-NWNIKLTDWGLATTDKTSMERN 221
TK++T+II QI+DA+EYVH++GIYHRDIKPENILI+G +W IKLTDWGLATTDKTSM+RN
Sbjct: 181 TKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRN 240
Query: 222 VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFC 281
VGSERYM+PELF+SNLD +ER + YDCAKVD+WA+GIV LNIVFHKNPF++ANQ+DK+FC
Sbjct: 241 VGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIANQSDKSFC 300
Query: 282 YFAANREALFDVFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSL 341
YFAANREALFDVFSTM+YDFFQVLR++LTIDP NR+L+ +RTE++ LSEYT+DDEYYN+L
Sbjct: 301 YFAANREALFDVFSTMAYDFFQVLRYSLTIDPANRDLKMMRTELQNLSEYTLDDEYYNNL 360
Query: 342 DSDEESVFYNYXXXXXXXXXXXXXXXXXXXXXXXXLHSXXXXXXXXXXSGIISTVSAVGE 401
D E + H + V E
Sbjct: 361 DEGYEETMIDGLPPQPVPPSSAPVSLPTPISSSNKQHMPEFKKDF--------NFNNVNE 412
Query: 402 TGQTPQKPPAITVEEITPEPSVKQNKEPVPRFTFTKRSHNRSKSNGYQXXXXXXXXXPAK 461
++ +PS +Q K + T +H R+KS K
Sbjct: 413 RKRSDVSQNQNVASGFFKKPSTQQQKFFNQGYNTTLSTHERAKS--------APKFKFKK 464
Query: 462 HDAYGAGGYKNYKSXXXXXXXXXXXXXXXXSRKPLAIPTPNTHINNFFHEYKSRDDVDDF 521
+ YG N S SRKPL IPTPNTH+NNFFH+YK+R D+F
Sbjct: 465 RNKYGR--TDNQFSKPVNIEDRKKSKILKKSRKPLGIPTPNTHMNNFFHDYKAR---DEF 519
Query: 522 NTRDYFTPPSVHNRYMEGVFSKKNKRFNQWSKSPKXXXXXXXXXXXXSFNQDNTGN---- 577
NTRD+FTPPSV +RYMEG + NK++ Q +++ ++N N GN
Sbjct: 520 NTRDFFTPPSVQHRYMEGFSNNNNKQYRQ-NRNYNNNNNNSNNNHGSNYNNFNNGNSYIK 578
Query: 578 ------RKYVPP-------------------HSRKSFDVG-------------------- 592
KY P H+ S G
Sbjct: 579 GWNKNFNKYRRPSSSSYTGKSPLSRYNMSYNHNNNSSINGYARRGSTTTVQHSPGAYIPP 638
Query: 593 -------SPSIPHLSSKHEEQPPIHTM--------TYHEQHALSVDNEPELDDVLFTLEE 637
SP+ L P I T+ ++ Q ++ + + + DDVLFTLEE
Sbjct: 639 NARNHHVSPTNQFLRVPQSTAPDISTVLGGKPSYQEHYTQDSMDSEGDHDSDDVLFTLEE 698
Query: 638 SDGFDGFINDMSDLSIN-----TQQSSH-------SVNLTANG----------------- 668
D F+N M +LSIN T SH S N NG
Sbjct: 699 GD--HDFVNGMDNLSINDHLPHTTVGSHNEVFVHASTNHNNNGNNNHIDTNSTTNQYHRQ 756
Query: 669 -------------NNNQGPHGLPDLFKSPQVSHVNIN------DPL---NNHVTLAHSA- 705
NNN + LPDL KSP S ++N DP+ N +HS+
Sbjct: 757 YIPPPLTTSLHINNNNNESNELPDLLKSPASSEAHLNLSSGPIDPILTGNIGNRYSHSSD 816
Query: 706 ------RRPTTSSDKGISGVYVPPHHRKSFNIG-------------------HDNLVPGQ 740
R + K +GVYVPPHHRKSFN+G H+++ G
Sbjct: 817 SKELEQERRLSMEQKFKNGVYVPPHHRKSFNLGTQVPPMNMKTSNEATLSVSHNSVNFGG 876
Query: 741 HTNGLKRNSFGNRKP---XXXXXXXXXXLNAQDRFI------LPHNPYLSAASTSLQKND 791
N +R+S P A+ F+ LP N S+ + +LQ D
Sbjct: 877 SYNS-RRSSANESNPLHMNKALEKLSSSPGAKSSFVGFPKPLLPRNH--SSTTIALQNED 933
Query: 792 VFID--NDAVFFEDDE--------PHFFSAGRVNSPG----------------------- 818
VF D NDA+ FED+E H G N
Sbjct: 934 VFADSNNDAIIFEDEEYEGESDKMAHGKMEGGDNESSSTSPDERQIFGPYEIYAQTFAGS 993
Query: 819 ----KIRTGRKSSSKQDEVVGSLEQYKNNWLMLQQ 849
K+ GRK+S QDE+VGSLEQYKNNWL+LQQ
Sbjct: 994 THDKKLGAGRKTSI-QDEMVGSLEQYKNNWLILQQ 1027
>SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase
Length = 474
Score = 176 bits (447), Expect = 1e-43
Identities = 98/247 (39%), Positives = 145/247 (58%), Gaps = 19/247 (7%)
Query: 114 LYEVDI--QTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPR---KTK 164
L EV+I Q +H+NI + F+ Y+++EYC GDLYE I ++ P + +
Sbjct: 53 LQEVNILRQLSRSRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPE 112
Query: 165 NVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWN-----IKLTDWGLATTDKTSME 219
+ NI QI+D V ++HS GIYHRD+KPEN L++ + + +K++D+GLA DK S +
Sbjct: 113 MIKNIFLQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLACRDKISYD 172
Query: 220 RNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKA 279
GS+RYMAPE FE E Y DIWA+GI +LN++F +NPFT ++ D
Sbjct: 173 FGTGSDRYMAPEQFE-----EVDGAGYSPRAADIWALGICLLNLIFARNPFTYPHEKDPI 227
Query: 280 FCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEYTMDDEYYN 339
F + + LFDVF T+S D + VLR L + P R+L K R + ++++T DDE
Sbjct: 228 FADYMLDAMTLFDVFPTLSQDTYNVLRACLCVSPEKRSLAKTREAVLAVTKWTTDDEELE 287
Query: 340 SLDSDEE 346
S ++EE
Sbjct: 288 SFVNEEE 294
>YDR247w [T] KOG0583 Serine/threonine protein kinase
Length = 461
Score = 123 bits (309), Expect = 1e-27
Identities = 96/341 (28%), Positives = 168/341 (49%), Gaps = 37/341 (10%)
Query: 16 DRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDET 75
+ Y + I EG+YG V A D + + A+K + +S GV D +D+
Sbjct: 10 NNYLITSQIGEGAYGLVYRALDIRTDRQYAIKAVVQSY---------GVSKEADMGNDKI 60
Query: 76 NNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALY-------EVDIQTKIGKHKN 128
+ Q+K +L K K+++ + S E + E+ + ++ HKN
Sbjct: 61 HKNSVKLQKKLAKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKN 120
Query: 129 ITELYDFFDS----YIIMEYCSGGDLYEAIKDDM-VPRKTKNVTNIINQILDAVEYVHSR 183
I +++ S +I+M+Y DL+ +I D+ V + QI A+ Y H
Sbjct: 121 IVTIHEVLQSAVCTFIVMDYYPT-DLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEH 179
Query: 184 GIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV--GSERYMAPE--LFESNLDR 239
GIYH DIKPEN+L+ N+ L D+GL+TT T ++ NV GS YM PE F+ +
Sbjct: 180 GIYHCDIKPENLLLDTEDNVFLCDFGLSTT-STYIKPNVCIGSSYYMPPERISFDGRVS- 237
Query: 240 EERTDAYDCAKV------DIWAIGIVMLNIVFHKNPFTVANQT-DKAFCYFAANREALFD 292
++ + KV D+W++GI+++N+ +NP+ A++T D + YF + L
Sbjct: 238 SSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQ 297
Query: 293 VFSTMSYDFFQVLRHALTIDPTNR-NLEKVRTEIKRLSEYT 332
+ +S DF+ +L L ++P NR +L+++ E+ ++ +T
Sbjct: 298 IL-PLSDDFYSLLSKILQVNPKNRMSLQELMKEVSSITSFT 337
>YPL026c [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 112 bits (279), Expect = 3e-24
Identities = 97/347 (27%), Positives = 162/347 (45%), Gaps = 38/347 (10%)
Query: 14 LRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDD 73
L + +++ I G+YG V D + AVK +FKS K+G+
Sbjct: 6 LLNNFRITAQIGSGAYGLVFHVVDILTSREYAVKTVFKSSSMDEFYNKNGL--------- 56
Query: 74 ETNNTVNSSQEKKQRLLKH-----QKSLIS-----DKVLSRFSNNVCFEALY-EVDIQTK 122
NN+ + Q L H QK L D +L N + Y E+ Q +
Sbjct: 57 -NNNSQVARTTLLQTQLYHFFKSFQKKLFLPSVDLDSILQLTENELNRLPHYREIAFQLR 115
Query: 123 IGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDM-VPRKTKNVTNIINQILDAV 177
+ H NI +++ +S +I+M+Y DL+ +I DD + + Q+ A+
Sbjct: 116 VQSHGNIVKIHQVLESSIATFIVMDYYDR-DLFTSIVDDKHFVNHGILIKKVFLQLCSAL 174
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDK-TSMERNVGSERYMAPELF--- 233
++ H GIYH DIKPEN+L+ N N L D+GL+T K + VGS YMAPE
Sbjct: 175 DHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLSTKSKYLAPNVCVGSSYYMAPERILYC 234
Query: 234 ----ESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQ-TDKAFCYFAANRE 288
+ + +E + DIW++GI+++N+ +NP+ A+Q D F +FA +
Sbjct: 235 LNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPWLKAHQKEDNTFQHFANDNN 294
Query: 289 ALFDVFSTMSYDFFQVLRHALTIDPTNR-NLEKVRTEIKRLSEYTMD 334
L + +S + F VL L ++P R +++ + +E+ L+ +T +
Sbjct: 295 VLKKIL-PISDELFTVLTKILQLNPYTRIDMKTLMSEVSSLTSFTRE 340
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 107 bits (266), Expect = 1e-22
Identities = 78/240 (32%), Positives = 124/240 (51%), Gaps = 25/240 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV +Q+K KH N+ L D S +II+E GGDL++ I+ D V +
Sbjct: 65 EVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPD-VGVDSDVAQFYFQ 123
Query: 172 QILDAVEYVHSR-GIYHRDIKPENILIAGNWNIKLTDWGLAT-------TDKTSMERNVG 223
Q++ A+ Y+H G+ HRDIKPENIL+ N N+KL D+GLA+ T + SM++ G
Sbjct: 124 QLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQR-G 182
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYF 283
S YMAPE+ S + Y + DIW+IGI++ ++ + P+ + + ++ F +F
Sbjct: 183 SPPYMAPEVLYSE-------EGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFF 235
Query: 284 AANREAL-FDVFSTMSYDFFQVLRHALTIDPTNR---NLEKVRTEIKRLSEYTMDDEYYN 339
N L + +S + + +LR L DP R K+ + R + ++ DD N
Sbjct: 236 IENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWVLRRASFSGDDGLCN 295
>SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase
Length = 470
Score = 106 bits (264), Expect = 2e-22
Identities = 87/327 (26%), Positives = 144/327 (43%), Gaps = 73/327 (22%)
Query: 11 GGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDE 70
G +L D + + I G+YG V A D L AVK + KDG+
Sbjct: 11 GQVLGDSLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKAL----------CKDGL------ 54
Query: 71 KDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNIT 130
N Q+K Q E+ + ++ H I
Sbjct: 55 ---------NEKQKKLQAR--------------------------ELALHARVSSHPYII 79
Query: 131 ELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKN-VTNIINQILDAVEYVHSRGI 185
L+ ++ Y++++YC GDL+ I + V + + + + Q++ AVE+ HS GI
Sbjct: 80 TLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSVGI 139
Query: 186 YHRDIKPENILIAGNWN-IKLTDWGLATTDKTSMERNVGSERYMAPELFE-----SNLDR 239
YHRD+KPENI++ + N + L D+GLATT+ S + GS YM+PE S+L
Sbjct: 140 YHRDLKPENIMVGNDVNTVYLADFGLATTEPYSSDFGCGSLFYMSPECQREVKKLSSLSD 199
Query: 240 ---------EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVA-NQTDKAFCYFAANREA 289
E ++ ++ A D+WA+GI+++N+ +NP+ A +QTD + + N
Sbjct: 200 MLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWKRACSQTDGTYRSYVHNPST 259
Query: 290 LFDVFSTMSYDFFQVLRHALTIDPTNR 316
L + +S + +L +P R
Sbjct: 260 LLSIL-PISRELNSLLNRIFDRNPKTR 285
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 102 bits (254), Expect = 2e-21
Identities = 63/207 (30%), Positives = 105/207 (50%), Gaps = 10/207 (4%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ I ++ H I +L D F+S +++ E C G+L++ + +V K I+
Sbjct: 77 EISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTS-VVTLSEKKTRTIMR 135
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA--TTDKTSMERNVGSERYMA 229
QI + VEY+H++ I HRD+KPENIL+ N N+K+TD+G A + + G+ Y+A
Sbjct: 136 QIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLA 195
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREA 289
PE + N+ E + Y +VDIWA G++M ++ PF Q
Sbjct: 196 PETLKCNM--FEGSPGYS-QEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSF 252
Query: 290 LFDVFSTMSYDFFQVLRHALTIDPTNR 316
++ +S D ++R L +DP+ R
Sbjct: 253 TSPEWADISEDPKDLIRKCLVVDPSQR 279
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 101 bits (252), Expect = 4e-21
Identities = 63/213 (29%), Positives = 106/213 (49%), Gaps = 34/213 (15%)
Query: 71 KDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNIT 130
++ ET V K+++LKH+ + E + K+ KH N+
Sbjct: 32 RNSETGEPVALKILDKEKVLKHKMA----------------EQIRREIATMKLIKHPNVV 75
Query: 131 ELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIY 186
+LY+ S +II+EY +GG+L++ I +D K Q++ AV+Y HSRG+Y
Sbjct: 76 QLYEVMASKTKIFIILEYVTGGELFDKIVNDG-RMKEDEARRYFQQLIHAVDYCHSRGVY 134
Query: 187 HRDIKPENILIAGNWNIKLTDWGLA-----TTDKTSMERNVGSERYMAPELFESNLDREE 241
HRD+KPEN+L+ N+K++D+GL+ D + + G+ Y+APE+
Sbjct: 135 HRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDR----- 189
Query: 242 RTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
YD A D+W+ G+V+ ++ PF +N
Sbjct: 190 ---GYDGATADMWSCGVVLYVLLAGYLPFDDSN 219
>YGR052w [T] KOG0583 Serine/threonine protein kinase
Length = 369
Score = 99.8 bits (247), Expect = 2e-20
Identities = 63/175 (36%), Positives = 88/175 (50%), Gaps = 21/175 (12%)
Query: 119 IQTKIGKHKNITELYDFF--DSYIIM--EYCSGGDLYEAI---KDDMVPRKTK----NVT 167
I + H NI + DF+ DSY IM EYC GDLY+ + K P ++
Sbjct: 52 ILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQ 111
Query: 168 NIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNVGSERY 227
II Q+ A+ + HS GI HRDIKPENIL+ N +IKL DWG A S + +G++ Y
Sbjct: 112 KIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNY 171
Query: 228 MAPE---------LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVA 273
APE F+ N DR Y+ + D W++G + ++F F V+
Sbjct: 172 RAPETFSGRVSNSCFKKNFDRSS-APLYNTYQADYWSLGATIFYLMFGDCLFRVS 225
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 99.8 bits (247), Expect = 2e-20
Identities = 77/280 (27%), Positives = 131/280 (46%), Gaps = 31/280 (11%)
Query: 78 TVNSSQEKKQRLLKHQKS--LISDKVLSRFS-NNVCFEALYEVDIQTKIGKHKNITELYD 134
T+ K +L +H + ++ K++ + N + L+ KI H NI +L++
Sbjct: 65 TIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 124
Query: 135 FFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDI 190
++ Y++MEY SGG++++ + K K QI+ AV+Y H + I HRD+
Sbjct: 125 VIETEKTLYLVMEYASGGEVFDYLVAHG-RMKEKEARAKFRQIVSAVQYCHQKYIVHRDL 183
Query: 191 KPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDC 248
K EN+L+ G+ NIK+ D+G + T ++ GS Y APELF+ YD
Sbjct: 184 KAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGK--------KYDG 235
Query: 249 AKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHA 308
+VD+W++G+++ +V PF N + F MS D +L+
Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKL 291
Query: 309 LTIDPTNR-NLEKVRT--------EIKRLSEYTMDDEYYN 339
L ++P R +LE++ E + L YT D +N
Sbjct: 292 LVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFN 331
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 99.4 bits (246), Expect = 2e-20
Identities = 69/218 (31%), Positives = 108/218 (48%), Gaps = 23/218 (10%)
Query: 107 NNVCFEALY-EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYE-AIKDDMVP 160
N + + LY EV+I K+ H NI L +S Y++MEY SGG+L+ +K+ +
Sbjct: 100 NTIARQKLYREVNIMKKLN-HPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMR 158
Query: 161 RKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATT--DKTSM 218
+ V + Q++ A+EY HS+ I HRD+K EN+L+ +K+ D+G +TT K +
Sbjct: 159 ERDARV--LFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPL 216
Query: 219 ERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDK 278
E GS Y APELF R Y +VD W++G+V+ +V PF N +
Sbjct: 217 ETFCGSPPYAAPELF--------RGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKEL 268
Query: 279 AFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ V S + ++R L ++PT R
Sbjct: 269 RDRVLRGKYRVPYYV----SIECESLIRKFLVLNPTQR 302
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 98.2 bits (243), Expect = 5e-20
Identities = 53/162 (32%), Positives = 85/162 (51%), Gaps = 19/162 (11%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
+I KH N+ ELY+ + Y ++EYC GG+L+ + + K Q++ AV
Sbjct: 65 RIAKHPNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGKL--KEDVAWKYFYQLISAV 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS-----MERNVGSERYMAPEL 232
++ HSRG+YHRDIKPEN+L+ N N+K++D+GL+ + G+ Y+APE+
Sbjct: 123 DFCHSRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
Y+ K DIW+ G+V+ ++ PF N
Sbjct: 183 INRK--------GYEGTKADIWSCGVVLFVLLAGYLPFHDTN 216
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 97.8 bits (242), Expect = 6e-20
Identities = 50/162 (30%), Positives = 90/162 (54%), Gaps = 16/162 (9%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ KH N+ +++ S Y ++E+ +GG+L++ I + K Q+++AV
Sbjct: 84 KLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNG-RLKEDEARKYFQQLINAV 142
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS---MERNVGSERYMAPELFE 234
+Y HSRG+YHRD+KPEN+L+ N +K++D+GL+ + + G+ Y+APE+
Sbjct: 143 DYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVIN 202
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQT 276
+ YD AK D+W+ G+++ ++ PF +N T
Sbjct: 203 NK--------GYDGAKADLWSCGVILFVLMAGYLPFEDSNLT 236
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 97.4 bits (241), Expect = 8e-20
Identities = 65/257 (25%), Positives = 120/257 (46%), Gaps = 27/257 (10%)
Query: 78 TVNSSQEKKQRLLKHQKS-------LISDKVLSRFSNNVCFEALYEVDIQT-----KIGK 125
T+ K +L +H+++ +IS + + N+ +++ +I+ K+
Sbjct: 26 TLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLS 85
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H N+ LYD +++ Y+I+EY G+L+ + D P + N QI+ + Y H
Sbjct: 86 HPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHG-PLPEREAINCFRQIIIGISYCH 144
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDR 239
+ GI HRD+KPEN+L+ +NIK+ D+G+A TD +E + GS Y APE+
Sbjct: 145 ALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGL--- 201
Query: 240 EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSY 299
Y+ D+W+ G+++ ++ + PF N + + + +S
Sbjct: 202 -----PYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISR 256
Query: 300 DFFQVLRHALTIDPTNR 316
D ++ L +DP R
Sbjct: 257 DAQDLIGKILVVDPRQR 273
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 97.4 bits (241), Expect = 8e-20
Identities = 66/246 (26%), Positives = 113/246 (45%), Gaps = 31/246 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ I ++ +H NI +L++ + Y +MEY GG+L+ + + K +
Sbjct: 74 EISILRRV-RHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRL--KEEVARKYFQ 130
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSER 226
Q++ AV + H+RG+YHRD+KPEN+L+ N N+K++D+GL+ + + G+
Sbjct: 131 QLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA 190
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ YD AKVDIW+ G+++ ++ PF N +
Sbjct: 191 YVAPEVLARK--------GYDAAKVDIWSCGVILFVLMAGYLPFHDRN----VMAMYKKI 238
Query: 287 REALFDVFSTMSYDFFQVLRHALTIDPTNR-------NLEKVRTEIKRLSEYTMDDEYYN 339
F S + ++L L +P R + K + Y DD+ N
Sbjct: 239 YRGEFRCPRWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFKKGFKHIKFYVEDDKLCN 298
Query: 340 SLDSDE 345
+D DE
Sbjct: 299 VVDDDE 304
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 97.1 bits (240), Expect = 1e-19
Identities = 68/239 (28%), Positives = 119/239 (49%), Gaps = 26/239 (10%)
Query: 122 KIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAI-KDDMVPRKTKNVTNIINQILDA 176
K+ +H +I +LY D +++MEY SGG+L++ I K+ + K + QIL
Sbjct: 71 KLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESR--RLFQQILSG 128
Query: 177 VEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFE 234
V+Y H + HRD+KPEN+L+ + N K+ D+GL+ +D + + GS Y APE+
Sbjct: 129 VDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVIS 188
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVF 294
L Y +VDIW+ G+++ ++ PF D F + +F
Sbjct: 189 GRL--------YAGPEVDIWSSGVILYALLCGTLPF----DDDHVPTLFKKICDGIFYTP 236
Query: 295 STMSYDFFQVLRHALTIDPTNR-NLEKVRTE---IKRLSEYTM-DDEYYNSLDSDEESV 348
++ +L+H L +DP R +++ +R + L +Y +D Y+S D+E++
Sbjct: 237 QYLNPSVISLLKHMLQVDPMKRASIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEAL 295
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 97.1 bits (240), Expect = 1e-19
Identities = 72/251 (28%), Positives = 122/251 (47%), Gaps = 26/251 (10%)
Query: 78 TVNSSQEKKQRLLKHQKS--LISDKVLSRFSNNVCFEALYEVDIQTKIGK---HKNITEL 132
T+ K +L KH + ++ K++ + + N +L ++ + KI K H NI +L
Sbjct: 127 TIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNP--SSLQKLFREVKIMKQLDHPNIVKL 184
Query: 133 YDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHR 188
Y ++ Y+++EY SGG++++ + K K QI+ AV+Y+HS+ I HR
Sbjct: 185 YQVMETEQTLYLVLEYASGGEVFDYLVAHG-RMKEKEARAKFRQIVSAVQYLHSKNIIHR 243
Query: 189 DIKPENILIAGNWNIKLTDWGLATTDK--TSMERNVGSERYMAPELFESNLDREERTDAY 246
D+K EN+L+ + NIK+ D+G + T ++ GS Y APELF Y
Sbjct: 244 DLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGK--------KY 295
Query: 247 DCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLR 306
D +VD+W++G+++ +V PF N + F MS D +L+
Sbjct: 296 DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLK 351
Query: 307 HALTIDPTNRN 317
L I+P R+
Sbjct: 352 KFLVINPQRRS 362
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 97.1 bits (240), Expect = 1e-19
Identities = 72/251 (28%), Positives = 122/251 (47%), Gaps = 26/251 (10%)
Query: 78 TVNSSQEKKQRLLKHQKS--LISDKVLSRFSNNVCFEALYEVDIQTKIGK---HKNITEL 132
T+ K +L KH + ++ K++ + + N +L ++ + KI K H NI +L
Sbjct: 175 TIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNP--SSLQKLFREVKIMKQLDHPNIVKL 232
Query: 133 YDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHR 188
Y ++ Y+++EY SGG++++ + K K QI+ AV+Y+HS+ I HR
Sbjct: 233 YQVMETEQTLYLVLEYASGGEVFDYLVAHG-RMKEKEARAKFRQIVSAVQYLHSKNIIHR 291
Query: 189 DIKPENILIAGNWNIKLTDWGLATTDK--TSMERNVGSERYMAPELFESNLDREERTDAY 246
D+K EN+L+ + NIK+ D+G + T ++ GS Y APELF Y
Sbjct: 292 DLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGK--------KY 343
Query: 247 DCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLR 306
D +VD+W++G+++ +V PF N + F MS D +L+
Sbjct: 344 DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLK 399
Query: 307 HALTIDPTNRN 317
L I+P R+
Sbjct: 400 KFLVINPQRRS 410
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 97.1 bits (240), Expect = 1e-19
Identities = 52/162 (32%), Positives = 86/162 (52%), Gaps = 19/162 (11%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
+I +H N+ ELY+ + Y +MEYC GG+L+ + + + Q+++AV
Sbjct: 65 RIARHPNVVELYEVMATKTRIYFVMEYCKGGELFNKVAKGKL--RDDVAWKYFYQLINAV 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS-----MERNVGSERYMAPEL 232
++ HSR +YHRDIKPEN+L+ N N+K++D+GL+ + G+ Y+APE+
Sbjct: 123 DFCHSREVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
YD K DIW+ G+V+ ++ PF +N
Sbjct: 183 INRK--------GYDGTKADIWSCGVVLFVLLAGYLPFHDSN 216
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 97.1 bits (240), Expect = 1e-19
Identities = 53/166 (31%), Positives = 94/166 (55%), Gaps = 17/166 (10%)
Query: 112 EALYEVDIQT-KIGKHKNITELYDFFDSY----IIMEYCSGGDLYEAIKDDMVPRKTKNV 166
E+ + +I+T K+ H NI ++++ + I+MEY SGG L + + + K +
Sbjct: 54 ESQVKREIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKM--KESDA 111
Query: 167 TNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS--MERNVGS 224
+ Q++DAV+Y H+RG+YHRD+KP+N+L+ N+K++D+GL+ K+ + GS
Sbjct: 112 RKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGDMLSTACGS 171
Query: 225 ERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
Y+APEL + Y A VD+W+ G+++ ++ PF
Sbjct: 172 PCYIAPELIMNK--------GYSGAAVDVWSCGVILFELLAGYPPF 209
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 96.7 bits (239), Expect = 1e-19
Identities = 77/305 (25%), Positives = 129/305 (42%), Gaps = 52/305 (17%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
+KL E + GS G V LA + + AVK I K+ + GN + G ++G D
Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVS--GTSIVGSTTPDALPY 76
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF- 136
+ ++ +I K+L+ H N+ LYD +
Sbjct: 77 GI-------------EREIIIMKLLN----------------------HPNVLRLYDVWE 101
Query: 137 ---DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPE 193
D Y+++EY G+L+ + + P QI+ V Y H+ GI HRD+KPE
Sbjct: 102 TNTDLYLVLEYAEKGELFNLLVE-RGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPE 160
Query: 194 NILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKV 251
N+L+ +NIK+ D+G+A T+ +E + GS Y APE+ Y
Sbjct: 161 NLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSG--------IPYQGFAS 212
Query: 252 DIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTI 311
D+W+ G+++ ++ + PF + + E +S + ++R LT+
Sbjct: 213 DVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTV 272
Query: 312 DPTNR 316
DP R
Sbjct: 273 DPERR 277
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 96.3 bits (238), Expect = 2e-19
Identities = 58/212 (27%), Positives = 107/212 (50%), Gaps = 23/212 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNI-I 170
E+ + HKNI Y+ ++ ++++E+ GGDL++ I+ D+ ++V
Sbjct: 61 EIQLHKLCNGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDV--GIDEDVAQFYF 118
Query: 171 NQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATT-----DKTSMERNVGSE 225
Q+++ + ++HS+G+ HRD+KPENIL+ N N+K++D+G A+ + VGS
Sbjct: 119 AQLMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSP 178
Query: 226 RYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVA-NQTDKAFCYFA 284
Y APE+ T YD +KVD+W+ GI++ ++ P+ A + T Y
Sbjct: 179 PYAAPEI----------TQQYDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKK 228
Query: 285 ANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ ++ +S + ++ L DP R
Sbjct: 229 QCERPSYHPWNLLSPGAYSIITGMLRSDPFKR 260
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 95.9 bits (237), Expect = 2e-19
Identities = 63/236 (26%), Positives = 114/236 (47%), Gaps = 42/236 (17%)
Query: 94 KSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGD 149
K +S+ VL + + L E H ++ LYD +++ Y+++E+ SGG+
Sbjct: 80 KEKLSESVLQKVEREIAIMKLIE---------HPHVLHLYDVYENKKYLYLLLEHVSGGE 130
Query: 150 LYEAIKDDMVPRK----TKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKL 205
L+ D + RK +K QI+ A+++ H+ I HRD+KPEN+L+ NIK+
Sbjct: 131 LF-----DYLVRKGRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIKV 185
Query: 206 TDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNI 263
D+G+A+ + + +E + GS Y PE+ R + YD K D+W+ G+++ +
Sbjct: 186 ADFGMASLQVEGSMLETSCGSPHYACPEVI--------RGEKYDGRKADVWSCGVILYAL 237
Query: 264 VFHKNPF---TVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ PF + N +K + +F + + D +LR + +DP R
Sbjct: 238 LVGALPFDDDNLRNLLEKV-------KRGVFHIPHFVPADVQSLLRAMIEVDPGKR 286
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 95.5 bits (236), Expect = 3e-19
Identities = 73/278 (26%), Positives = 126/278 (45%), Gaps = 32/278 (11%)
Query: 78 TVNSSQEKKQRLLKH--QKSLISDKVLSRFS-NNVCFEALYEVDIQTKIGKHKNITELYD 134
T+ K +L +H ++ K++ + N+ + L+ K+ H NI +L++
Sbjct: 25 TIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE 84
Query: 135 FFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDI 190
++ Y++MEY SGG++++ + K K QI+ AV+Y H + I HRD+
Sbjct: 85 VIETEKTLYLVMEYASGGEVFDYLVAHG-RMKEKEARAKFRQIVSAVQYCHQKFIVHRDL 143
Query: 191 KPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDC 248
K EN+L+ + NIK+ D+G + T ++ GS Y APELF+ YD
Sbjct: 144 KAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK--------KYDG 195
Query: 249 AKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHA 308
+VD+W++G+++ +V PF N + F MS D +L+
Sbjct: 196 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKF 251
Query: 309 LTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSLDSDEE 346
L ++P+ R E M D + N D+E
Sbjct: 252 LILNPSKRG----------TLEQIMKDRWMNVGHEDDE 279
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 95.5 bits (236), Expect = 3e-19
Identities = 73/278 (26%), Positives = 126/278 (45%), Gaps = 32/278 (11%)
Query: 78 TVNSSQEKKQRLLKH--QKSLISDKVLSRFS-NNVCFEALYEVDIQTKIGKHKNITELYD 134
T+ K +L +H ++ K++ + N+ + L+ K+ H NI +L++
Sbjct: 25 TIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE 84
Query: 135 FFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDI 190
++ Y++MEY SGG++++ + K K QI+ AV+Y H + I HRD+
Sbjct: 85 VIETEKTLYLVMEYASGGEVFDYLVAHG-RMKEKEARAKFRQIVSAVQYCHQKFIVHRDL 143
Query: 191 KPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDC 248
K EN+L+ + NIK+ D+G + T ++ GS Y APELF+ YD
Sbjct: 144 KAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK--------KYDG 195
Query: 249 AKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHA 308
+VD+W++G+++ +V PF N + F MS D +L+
Sbjct: 196 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKF 251
Query: 309 LTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSLDSDEE 346
L ++P+ R E M D + N D+E
Sbjct: 252 LILNPSKRG----------TLEQIMKDRWMNVGHEDDE 279
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 95.5 bits (236), Expect = 3e-19
Identities = 73/278 (26%), Positives = 126/278 (45%), Gaps = 32/278 (11%)
Query: 78 TVNSSQEKKQRLLKH--QKSLISDKVLSRFS-NNVCFEALYEVDIQTKIGKHKNITELYD 134
T+ K +L +H ++ K++ + N+ + L+ K+ H NI +L++
Sbjct: 58 TIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE 117
Query: 135 FFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDI 190
++ Y++MEY SGG++++ + K K QI+ AV+Y H + I HRD+
Sbjct: 118 VIETEKTLYLVMEYASGGEVFDYLVAHG-RMKEKEARAKFRQIVSAVQYCHQKFIVHRDL 176
Query: 191 KPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDC 248
K EN+L+ + NIK+ D+G + T ++ GS Y APELF+ YD
Sbjct: 177 KAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK--------KYDG 228
Query: 249 AKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHA 308
+VD+W++G+++ +V PF N + F MS D +L+
Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKF 284
Query: 309 LTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSLDSDEE 346
L ++P+ R E M D + N D+E
Sbjct: 285 LILNPSKRG----------TLEQIMKDRWMNVGHEDDE 312
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 95.5 bits (236), Expect = 3e-19
Identities = 67/246 (27%), Positives = 124/246 (50%), Gaps = 31/246 (12%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ +H + LY+ S YII+EY +GG+L++ I + +++ +Q++D V
Sbjct: 62 KLVRHPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESE-ARKYFHQLIDGV 120
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDK---TSMERNVGSERYMAPELFE 234
+Y HS+G+YHRD+KPEN+L+ N+K++D+GL+ + T ++ G+ Y+APE+
Sbjct: 121 DYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLS 180
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVF 294
Y+ A DIW+ G+++ ++ PF ++ D Y ++ A F
Sbjct: 181 HK--------GYNGAVADIWSCGVILYVLMAGYLPF---DEMDLPTLYSKIDK-AEFSCP 228
Query: 295 STMSYDFFQVLRHALTIDPTNR-NLEKVRTEIKRLSEYT----MD------DEYYNSLDS 343
S + ++ L +P R + ++R + L +YT +D D+ Y + D
Sbjct: 229 SYFALGAKSLINRILDPNPETRITIAEIRKDEWFLKDYTPVQLIDYEHVNLDDVYAAFDD 288
Query: 344 DEESVF 349
EE +
Sbjct: 289 PEEQTY 294
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 95.1 bits (235), Expect = 4e-19
Identities = 78/269 (28%), Positives = 125/269 (45%), Gaps = 37/269 (13%)
Query: 61 KDGVMVIGDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEV--- 117
K G V+GD T+ K ++ +HQ L KV + N +L V
Sbjct: 12 KIGHYVLGD--------TLGVGTFGKVKIGEHQ--LTGHKVAVKILNRQKIRSLDVVGKI 61
Query: 118 --DIQT-KIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAI-KDDMVPRKTKNVTNI 169
+IQ K+ +H +I +LY D +++MEY SGG+L++ I K V + +
Sbjct: 62 KREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRV--EEMEARRL 119
Query: 170 INQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERY 227
QIL AV+Y H + HRD+KPEN+L+ + N K+ D+GL+ +D + + GS Y
Sbjct: 120 FQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNY 179
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANR 287
APE+ L Y +VDIW+ G+++ ++ PF + F R
Sbjct: 180 TAPEVISGRL--------YAGPEVDIWSCGVILYALLCGTLPF----DDEHVPTLFKKIR 227
Query: 288 EALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+F + ++ +L H L +DP R
Sbjct: 228 GGVFYIPEYLNRSVATLLMHMLQVDPLKR 256
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 95.1 bits (235), Expect = 4e-19
Identities = 51/157 (32%), Positives = 89/157 (56%), Gaps = 16/157 (10%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
KI +H NI LY+ S YI++E+ +GG+L++ I ++++ Q++DAV
Sbjct: 64 KIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESES-RKYFQQLVDAV 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSME---RNVGSERYMAPELFE 234
+ H +G+YHRD+KPEN+L+ N N+K++D+GL+ + +E G+ Y+APE+
Sbjct: 123 AHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLS 182
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFT 271
YD + DIW+ G+++ I+ PF+
Sbjct: 183 G--------QGYDGSAADIWSCGVILFVILAGYLPFS 211
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 94.7 bits (234), Expect = 5e-19
Identities = 64/207 (30%), Positives = 103/207 (48%), Gaps = 20/207 (9%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
KI H NI +L++ ++ Y+IMEY SGG +++ + K K + QI+ AV
Sbjct: 108 KILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHG-RMKEKEARSKFRQIVSAV 166
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFES 235
+Y H + I HRD+K EN+L+ + NIK+ D+G + T ++ GS Y APELF+
Sbjct: 167 QYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQG 226
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFS 295
YD +VD+W++G+++ +V PF N + F
Sbjct: 227 K--------KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF---- 274
Query: 296 TMSYDFFQVLRHALTIDPTNR-NLEKV 321
MS D +L+ L ++P R LE++
Sbjct: 275 YMSTDCENLLKRFLVLNPIKRGTLEQI 301
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 94.7 bits (234), Expect = 5e-19
Identities = 64/201 (31%), Positives = 106/201 (51%), Gaps = 21/201 (10%)
Query: 82 SQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS--- 138
S+EKK + + K L ++L V + E++IQ + +H NI LY +F
Sbjct: 61 SREKKTKRIIALKVLFKTQLLQL---GVSHQLKREIEIQYHL-RHPNILTLYGYFHDDKR 116
Query: 139 -YIIMEYCSGGDLYEAIKDDMVPRKTKNVTN-IINQILDAVEYVHSRGIYHRDIKPENIL 196
++I++Y S G+L+ ++ + + + + Q+ +A+ Y HS+G+ HRDIKPEN+L
Sbjct: 117 VFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLL 176
Query: 197 IAGNWNIKLTDWGLA-TTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWA 255
+ N+KL D+G + D + G+ Y+APE+ SN + VDIWA
Sbjct: 177 LDSKLNLKLADFGWSVVADHSKRHTLCGTMDYLAPEMV-SNQPHD--------FNVDIWA 227
Query: 256 IGIVMLNIVFHKNPFTVANQT 276
IGI++ ++ PF ANQT
Sbjct: 228 IGILLFEMLVGYAPF--ANQT 246
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 94.7 bits (234), Expect = 5e-19
Identities = 82/311 (26%), Positives = 133/311 (42%), Gaps = 81/311 (26%)
Query: 17 RYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETN 76
+YKLI+ I +G++ V LA K VA+K I K++ + G
Sbjct: 150 KYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPG------------------- 190
Query: 77 NTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF 136
S +K R ++ K L H NI +L+
Sbjct: 191 -----SLQKLFREVRIMKML----------------------------DHPNIVKLFQVI 217
Query: 137 DS----YIIMEYCSGGDLYE--AIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDI 190
++ Y+IMEY SGG++++ + M K K QI+ AV+Y H + I HRD+
Sbjct: 218 ETEKTLYLIMEYASGGEVFDYLVLHGRM---KEKEARVKFRQIVSAVQYCHQKRIIHRDL 274
Query: 191 KPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDC 248
K EN+L+ NIK+ D+G + T + ++ GS Y APELF+ YD
Sbjct: 275 KAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGK--------KYDG 326
Query: 249 AKVDIWAIGIVMLNIVFHKNPF---TVANQTDKAFCYFAANREALFDVFSTMSYDFFQVL 305
+VD+W++G+++ +V PF T+ ++ + + MS D +L
Sbjct: 327 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVL-------RGKYRIPFYMSTDCENLL 379
Query: 306 RHALTIDPTNR 316
R L ++P R
Sbjct: 380 RKFLVLNPAKR 390
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 94.4 bits (233), Expect = 7e-19
Identities = 70/242 (28%), Positives = 110/242 (44%), Gaps = 28/242 (11%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H NI +L++ ++ Y++MEY S G++++ + K K QI+ AV Y H
Sbjct: 115 HPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHG-RMKEKEARAKFRQIVSAVHYCH 173
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDR 239
+ I HRD+K EN+L+ NIK+ D+G + T + ++ GS Y APELF+
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGK--- 230
Query: 240 EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSY 299
YD +VDIW++G+++ +V PF N + F MS
Sbjct: 231 -----KYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF----YMST 281
Query: 300 DFFQVLRHALTIDPTNR-NLEKVRT--------EIKRLSEYTMDDEYYNSLDSDEESVFY 350
D +LR L ++P R LE++ E + L YT +E + E V
Sbjct: 282 DCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGM 341
Query: 351 NY 352
Y
Sbjct: 342 GY 343
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 94.0 bits (232), Expect = 9e-19
Identities = 74/265 (27%), Positives = 121/265 (44%), Gaps = 70/265 (26%)
Query: 14 LRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDD 73
L+ RY+L E + +G+YG V A++ ++VA+K I K DK D +D V +
Sbjct: 51 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRK---DKIKDEQDMVHI------- 100
Query: 74 ETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELY 133
E++I + + H +I +Y
Sbjct: 101 ----------------------------------------RREIEIMSSLN-HPHIISIY 119
Query: 134 DFFDS----YIIMEYCSGGDLYEAIKDD--MVPRKTKNVTNIINQILDAVEYVHSRGIYH 187
+ F++ IIMEY S G+LY+ I + + R+T++ QI+ AV Y H G+ H
Sbjct: 120 EVFENKDKIVIIMEYASKGELYDYISERRRLSERETRH---FFRQIVSAVHYCHKNGVVH 176
Query: 188 RDIKPENILIAGNWNIKLTDWGLATTDKTS--MERNVGSERYMAPELFESNLDREERTDA 245
RD+K ENIL+ N NIK+ D+GL+ + ++ GS Y +PE+
Sbjct: 177 RDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGR--------P 228
Query: 246 YDCAKVDIWAIGIVMLNIVFHKNPF 270
Y +VD WA+G+++ +V+ PF
Sbjct: 229 YRGPEVDSWALGVLLYTLVYGTMPF 253
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 94.0 bits (232), Expect = 9e-19
Identities = 64/215 (29%), Positives = 108/215 (49%), Gaps = 23/215 (10%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
+H +IT LY+ +S Y++ EY G++++ + + K + Q++ AV Y
Sbjct: 96 RHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANG-RMKEPEAARVFTQLVSAVHYC 154
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLD 238
H RG+ HRD+K EN+L+ + NIKL D+G + + +++ GS Y APE+F+
Sbjct: 155 HRRGVVHRDLKAENVLLDKDMNIKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGL-- 212
Query: 239 REERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREAL--FDVFST 296
YD K DIW++G+V+ +V PF D +R L F +
Sbjct: 213 ------EYDGPKSDIWSLGVVLYALVCGALPF------DGKTILELKSRVVLGKFRIPFF 260
Query: 297 MSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEY 331
MS + Q++R+ L ++P R K + + LSE+
Sbjct: 261 MSQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSEW 295
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 93.6 bits (231), Expect = 1e-18
Identities = 73/244 (29%), Positives = 118/244 (47%), Gaps = 27/244 (11%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALY-------EVDIQTKIGKHKNITELYDFFD----SY 139
K +S+++ K L+ + C A+ EV++ K+ H NI +YD+ SY
Sbjct: 190 KSDRSVVAIKQLNTQFSTRCSRAIAKTRDIRNEVEVMKKLS-HPNIVAIYDWITVAKYSY 248
Query: 140 IIMEYCSGGDLYEAIKDDMVPRKTKNVT---NIINQILDAVEYVHSRGIYHRDIKPENIL 196
+++EY GG+ + + D R + Q++DA+ Y+HS GI HRDIKPENIL
Sbjct: 249 MVIEYVGGGEFFSKVVDSKYNRMGLGESLGKYFAFQLIDAILYLHSVGICHRDIKPENIL 308
Query: 197 I---AGNWNIKLTDWGLATTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDI 253
A +KLTD+G+A M+ G+ Y APE+ + + E T KVDI
Sbjct: 309 CSDKAERCILKLTDFGMAKNSVNRMKTRCGTPSYNAPEIVAN--EGVEYT-----PKVDI 361
Query: 254 WAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDV-FSTMSYDFFQVLRHALTID 312
W++G V+ I F P TD +F + ++ + +++ LT++
Sbjct: 362 WSLGCVLF-ITFSGYPPFSEEYTDMTMDEQVLTGRLIFHAQWRRITVETQNMIKWMLTVE 420
Query: 313 PTNR 316
P+NR
Sbjct: 421 PSNR 424
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 93.6 bits (231), Expect = 1e-18
Identities = 57/182 (31%), Positives = 93/182 (50%), Gaps = 33/182 (18%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAI-KDDMVPRKTKNVTNIINQILDAVEY 179
+H N+ EL + + + +MEY +GG+L+E I +D +P Q++ AV++
Sbjct: 72 RHPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLAR--KYFQQLISAVDF 129
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT------------TDKTSMERNVGSERY 227
HSRG++HRDIKPEN+L+ G ++K+TD+GL+ + + G+ Y
Sbjct: 130 CHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAY 189
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIV------FHKNPFTVANQTDKAFC 281
+APE+ R YD A DIW+ GIV+ ++ +N T+ + KA C
Sbjct: 190 VAPEVL--------RNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAEC 241
Query: 282 YF 283
F
Sbjct: 242 EF 243
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 93.6 bits (231), Expect = 1e-18
Identities = 57/176 (32%), Positives = 95/176 (53%), Gaps = 19/176 (10%)
Query: 108 NVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKT 163
NV F+ E+ K+ KH NI L++ S Y+++E +GGDL++ I +T
Sbjct: 51 NVSFQIKREIRT-LKVLKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSET 109
Query: 164 KNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV- 222
+ + Q++D V Y H++G++HRD+K EN+L+ +IK+TD+GL+ + E +
Sbjct: 110 QG-RKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLL 168
Query: 223 ----GSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
GS Y+APE+ + + YD A DIW+ G+++ I+ PF AN
Sbjct: 169 HTTCGSPNYVAPEVLAN--------EGYDGAASDIWSCGVILYVILTGCLPFDDAN 216
>7291707 [T] KOG1152 Signal transduction serine/threonine kinase with
PAS/PAC sensor domain
Length = 1005
Score = 93.6 bits (231), Expect = 1e-18
Identities = 68/210 (32%), Positives = 109/210 (51%), Gaps = 19/210 (9%)
Query: 79 VNSSQEKKQRLLKHQKSLISDKVLSRF--SNNVCFEALYEVDIQTKIGKHKNITELYDFF 136
VN + RLL K ++ +K+ S+F + C E E+ + + HKNI + D F
Sbjct: 590 VNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTLN-HKNIVSVLDVF 648
Query: 137 DS----YIIME-YCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIK 191
++ ++ME + SG DL+ I+ + + K + I Q+ DAV Y+H + I HRDIK
Sbjct: 649 ENDLFYQLVMEKHGSGMDLWTFIERRPLMDE-KLGSYIFRQVADAVNYLHEQKILHRDIK 707
Query: 192 PENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCA 249
ENI+I N+ IKL D+G AT + G+ Y +PE+ N Y
Sbjct: 708 DENIIIDQNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGN--------RYVGP 759
Query: 250 KVDIWAIGIVMLNIVFHKNPFTVANQTDKA 279
+++IWA+G+ + ++F +NPF +T KA
Sbjct: 760 ELEIWALGVTLYVLMFFENPFIDVEETLKA 789
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 93.2 bits (230), Expect = 2e-18
Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 20/164 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ I ++ +H NI +L++ + Y +MEY GG+L+ + + K +
Sbjct: 76 EISILRRV-RHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRL--KEEMARKYFQ 132
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSER 226
Q++ AV + H RG+YHRD+KPEN+L+ N N+K++D+GL+ + + G+
Sbjct: 133 QLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA 192
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
Y+APE+ YD AKVDIW+ G+++ ++ PF
Sbjct: 193 YVAPEVLARK--------GYDGAKVDIWSCGVILFVLMAGFLPF 228
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 93.2 bits (230), Expect = 2e-18
Identities = 53/160 (33%), Positives = 86/160 (53%), Gaps = 20/160 (12%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H+N+ Y ++ Y+IM+ G L + +++ + ++ T + Q++ AVEY+H
Sbjct: 125 HENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRT-LFKQLVSAVEYIH 183
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-------GSERYMAPELFE 234
S+G+ HRDIK EN+L+ NWN+KL D+G A D + + V GS Y +PE+ +
Sbjct: 184 SKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILK 243
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
AYD DIWA G+V +VF + P+ +N
Sbjct: 244 G--------VAYDPFMSDIWACGVVCYAMVFGRLPYDGSN 275
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 92.8 bits (229), Expect = 2e-18
Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 23/201 (11%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYE-AIKDDMVPRKTKNVTNIINQILDAVEY 179
+H++I +LY ++ ++++EYC GG+L++ I D + + V + QI+ AV Y
Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRV--VFRQIVSAVAY 122
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV----GSERYMAPELFES 235
VHS+G HRD+KPEN+L +KL D+GL K + + ++ GS Y APEL +
Sbjct: 123 VHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQG 182
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFS 295
+Y ++ D+W++GI++ ++ PF D + +DV
Sbjct: 183 K--------SYLGSEADVWSMGILLYVLMCGFLPF----DDDNVMALYKKIMRGKYDVPK 230
Query: 296 TMSYDFFQVLRHALTIDPTNR 316
+S +L+ L +DP R
Sbjct: 231 WLSPSSILLLQQMLQVDPKKR 251
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 92.8 bits (229), Expect = 2e-18
Identities = 50/162 (30%), Positives = 86/162 (52%), Gaps = 18/162 (11%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ KH N+ E+ + S YI++E +GG+L++ I K Q+++AV
Sbjct: 72 KLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQG-RLKEDEARRYFQQLINAV 130
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSERYMAPEL 232
+Y HSRG+YHRD+KPEN+++ N +K++D+GL+ + E + G+ Y+APE+
Sbjct: 131 DYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEV 190
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
YD A D+W+ G+++ ++ PF N
Sbjct: 191 LSDK--------GYDGAAADVWSCGVILFVLMAGYLPFDEPN 224
>CE12478 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 484
Score = 92.4 bits (228), Expect = 3e-18
Identities = 60/223 (26%), Positives = 115/223 (50%), Gaps = 24/223 (10%)
Query: 116 EVDIQTKIGKHKNITELY----DFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ IQ + H+N+ ++ D Y+ +EY GGDLYE I + +
Sbjct: 73 EITIQESLTGHENVIQVLGKESDAQFCYMFLEYADGGDLYEKITSGC-SFSLEEAHSYFK 131
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNW-----NIKLTDWGLATTDKTS-----MERN 221
Q+++ ++++H R + HRDIKPEN+++ + ++K+ D+GLAT + E+
Sbjct: 132 QLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAELIFEQR 191
Query: 222 VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFC 281
GS Y+APE++ Y ++DIW+ G+V+L ++ + P+ T+K +
Sbjct: 192 CGSVEYVAPEIYTG--------AQYRGPQIDIWSAGVVLLAMLTRQLPWEFPCMTNKRYF 243
Query: 282 YFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR-NLEKVRT 323
++ NR A D ++ +S ++L L+ NR +E++++
Sbjct: 244 FWMKNRVAHIDAWNELSCRAKKLLWKMLSPGSENRATIEEIQS 286
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 92.4 bits (228), Expect = 3e-18
Identities = 72/242 (29%), Positives = 121/242 (49%), Gaps = 31/242 (12%)
Query: 86 KQRLLKHQKSL-ISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YI 140
+ R+ K++ ++ I DK S+ + EV+I ++ KH +I +LY ++ YI
Sbjct: 159 RHRITKNEVAIKIIDK--SQLDQTNLQKVYREVEIMKRL-KHPHIIKLYQVMETKNMIYI 215
Query: 141 IMEYCSGGDLYEAIKDDMVPRKTKNVTNI-INQILDAVEYVHSRGIYHRDIKPENILIAG 199
+ EY S G++++ I R +++ QI+ AVEY H +GI HRD+K EN+L+
Sbjct: 216 VSEYASQGEIFDYIAK--YGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDL 273
Query: 200 NWNIKLTDWGLATTDKTS--MERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIG 257
N NIK+ D+G + K + GS Y APE+FE Y ++DIW++G
Sbjct: 274 NMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGK--------QYTGPEIDIWSLG 325
Query: 258 IVMLNIVFHKNPF---TVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPT 314
+V+ +V PF T+ + D+ F + MS + ++R L ++PT
Sbjct: 326 VVLYVLVCGALPFDGSTLQSLRDRVL-------SGRFRIPFFMSSECEHLIRRMLVLEPT 378
Query: 315 NR 316
R
Sbjct: 379 RR 380
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 92.0 bits (227), Expect = 3e-18
Identities = 51/159 (32%), Positives = 87/159 (54%), Gaps = 27/159 (16%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTK----NVTNIINQILDAV 177
H+NI LY + ++ +I+MEYCSGG+++ D + RK + + Q++ A+
Sbjct: 66 HQNICRLYHYIETEDKFFIVMEYCSGGEMF-----DYIVRKERLEESEARHFFRQLVSAI 120
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT------TDKTSMERNVGSERYMAPE 231
+VHS+G HRD+KPEN+L+ + ++KL D+GL DK +++ GS Y APE
Sbjct: 121 AFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSPAYAAPE 180
Query: 232 LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
L + Y + D+W++GI++ ++ PF
Sbjct: 181 LIQGL--------QYKGNEADVWSMGILLYTLLVGALPF 211
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 91.7 bits (226), Expect = 4e-18
Identities = 73/229 (31%), Positives = 125/229 (53%), Gaps = 37/229 (16%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYE-AIKDDMVPRKTKNVTNII 170
E+DI + H + + ++ F++ +I+MEY GGDL + I + + + + ++
Sbjct: 219 EIDILKSL-HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQ--DCKPLL 275
Query: 171 NQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATT---DKTSMERNVGSERY 227
Q+L+ + ++H +G+ HRDIKPENILI ++++K++D+GLA T +E G+ Y
Sbjct: 276 KQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGY 335
Query: 228 MAPELFES---NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFA 284
+APE+ +S NLD YD KVDIW++G V+ ++ PF ++Q A C
Sbjct: 336 LAPEVLKSKNVNLD-----GGYD-DKVDIWSLGCVLYVMLTASIPFASSSQ---AKC--- 383
Query: 285 ANREALFDVFSTMSYDFFQVLRHALT---IDPTNRNLEKVRTEIKRLSE 330
++ S +Y +L + ++ ID NR LE + E KR+SE
Sbjct: 384 ------IELISKGAYPIEPLLENEISEEGIDLINRMLE-INPE-KRISE 424
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 91.7 bits (226), Expect = 4e-18
Identities = 72/248 (29%), Positives = 121/248 (48%), Gaps = 27/248 (10%)
Query: 78 TVNSSQEKKQRLLKHQKS--LISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF 135
T+ + RL KH K+ L + K++ ++ E L ++ +H NI LYD
Sbjct: 17 TLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYASIGMEIL-----MMRLLRHPNILRLYDV 71
Query: 136 FDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIK 191
+ Y+ +EY G+L+ I+ P + + ++QILDAV + H HRD+K
Sbjct: 72 WTDHQHMYLALEYVPDGELFHYIRKHG-PLSEREAAHYLSQILDAVAHCHRFRFRHRDLK 130
Query: 192 PENILIAGN-WNIKLTDWGLATTD--KTSMERNVGSERYMAPELFESNLDREERTDAYDC 248
ENILI N IK+ D+G+AT + + +E GS Y+APE+ Y
Sbjct: 131 LENILIKVNEQQIKIADFGMATVEPNDSCLENYCGSLHYLAPEIVSHK--------PYRG 182
Query: 249 AKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHA 308
A D+W+ G+++ +++ +K PF N TD + R +D+ S++S +L
Sbjct: 183 APADVWSCGVILYSLLSNKLPFGGQN-TD---VIYNKIRHGAYDLPSSISSAAQDLLHRM 238
Query: 309 LTIDPTNR 316
L ++P+ R
Sbjct: 239 LDVNPSTR 246
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 91.7 bits (226), Expect = 4e-18
Identities = 53/173 (30%), Positives = 94/173 (53%), Gaps = 20/173 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I ++ KH +I ELY++F+ Y+++E C G++ +K+ + P + ++
Sbjct: 60 EVKIHCQL-KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMH 118
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN---VGSERYM 228
QI+ + Y+HS GI HRD+ N+L+ N NIK+ D+GLAT K E++ G+ Y+
Sbjct: 119 QIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYI 178
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF---TVANQTDK 278
+PE+ T + + D+W++G + ++ + PF TV N +K
Sbjct: 179 SPEI---------ATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNK 222
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 91.7 bits (226), Expect = 4e-18
Identities = 53/173 (30%), Positives = 94/173 (53%), Gaps = 20/173 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I ++ KH +I ELY++F+ Y+++E C G++ +K+ + P + ++
Sbjct: 60 EVKIHCQL-KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMH 118
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN---VGSERYM 228
QI+ + Y+HS GI HRD+ N+L+ N NIK+ D+GLAT K E++ G+ Y+
Sbjct: 119 QIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYI 178
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF---TVANQTDK 278
+PE+ T + + D+W++G + ++ + PF TV N +K
Sbjct: 179 SPEI---------ATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNK 222
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 91.7 bits (226), Expect = 4e-18
Identities = 72/243 (29%), Positives = 116/243 (47%), Gaps = 33/243 (13%)
Query: 116 EVDIQTKIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAI--KDDMVPRKTKNVTNI 169
E+D K+ H +IT L+ D +++ME SGG+L+ I K + R+++
Sbjct: 72 EIDNLQKL-THPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRY--- 127
Query: 170 INQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERY 227
QI+ V Y H+ I HRD+KPEN+L+ N NIK+ D+GL+ TD + GS Y
Sbjct: 128 FQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTACGSPNY 187
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANR 287
APEL + L Y +VD+W+ G+++ ++ PF N FA +
Sbjct: 188 AAPELISNKL--------YVGPEVDLWSCGVILYAMLCGTLPFDDQNVP----TLFAKIK 235
Query: 288 EALFDVFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRL---SEYTMDDEYYNSLDSD 344
+ V +M ++ L +DP R ++KR+ S + +D YY + +
Sbjct: 236 SGRYTVPYSMEKQAADLISTMLQVDPVK------RADVKRIVNHSWFRIDLPYYLFPECE 289
Query: 345 EES 347
ES
Sbjct: 290 NES 292
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 91.7 bits (226), Expect = 4e-18
Identities = 47/164 (28%), Positives = 86/164 (51%), Gaps = 20/164 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ I ++ +H I L++ + Y +MEY GG+L+ + +P +T
Sbjct: 122 EISILRRV-RHPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAKGRLPEETAR--RYFQ 178
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSER 226
Q++ +V + H RG+YHRD+KPEN+L+ N+K++D+GL+ + + + G+
Sbjct: 179 QLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPA 238
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
Y+APE+ YD AK D+W+ G+++ ++ PF
Sbjct: 239 YIAPEVLTRK--------GYDAAKADVWSCGVILFVLMAGHIPF 274
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 91.7 bits (226), Expect = 4e-18
Identities = 61/230 (26%), Positives = 117/230 (50%), Gaps = 26/230 (11%)
Query: 97 ISDKVLSR--FSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDL 150
++ K+++R S +V + E+ I K+ H ++ L D +++ Y+I+E+ SGG+L
Sbjct: 44 VAIKIINREKLSESVLMKVEREIAIM-KLIDHPHVLGLSDVYENKKYLYLILEHVSGGEL 102
Query: 151 YEAI--KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDW 208
++ + K + P++ + QI+ A+++ HS I HRD+KPEN+L+ NIK+ D+
Sbjct: 103 FDYLVKKGRLTPKEARK---FFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADF 159
Query: 209 GLATTDK--TSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFH 266
G+A+ + +E + GS Y PE+ R + YD K D+W+ G+++ ++
Sbjct: 160 GMASLQPAGSMLETSCGSPHYACPEVI--------RGEKYDGRKADVWSCGVILYALLVG 211
Query: 267 KNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
PF D + +F + + D +LR + ++P R
Sbjct: 212 ALPF----DDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRR 257
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 91.3 bits (225), Expect = 6e-18
Identities = 68/209 (32%), Positives = 106/209 (50%), Gaps = 25/209 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV+IQT + H N+T+ Y +F Y++MEY G++Y+ ++ P ++ I
Sbjct: 152 EVEIQTSLN-HPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHG-PFNDILASDYIY 209
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV--GSERYMA 229
QI +A++Y+H + I HRDIKPENILI N IKLTD+G + + R G+ Y++
Sbjct: 210 QIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLS 269
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREA 289
PE+ ES YD +D WA+G++ ++ PF D + R A
Sbjct: 270 PEMVESR--------EYD-HTIDAWALGVLAFELLTGAPPFE-EEMKDTTY-----KRIA 314
Query: 290 LFDVF--STMSYDFFQVLRHALTIDPTNR 316
D+ S +S D ++ L DP +R
Sbjct: 315 ALDIKMPSNISQDAQDLILKLLKYDPKDR 343
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 91.3 bits (225), Expect = 6e-18
Identities = 58/204 (28%), Positives = 104/204 (50%), Gaps = 23/204 (11%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
++ +H NI EL + + + IMEY GG+L+ I + K + Q++ AV
Sbjct: 68 RLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGKL--KEDSARKYFQQLISAV 125
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSERYMAPEL 232
++ HSRG+ HRD+KPEN+L+ N ++K++D+GL+ + ++ + G+ Y+APE+
Sbjct: 126 DFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEV 185
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
R YD AK DIW+ GI++ ++ PF Q + + ++ F+
Sbjct: 186 L--------RKKGYDGAKGDIWSCGIILYVLLAGFLPF----QDENLMKMYRKIFKSEFE 233
Query: 293 VFSTMSYDFFQVLRHALTIDPTNR 316
S + +++ L +DP R
Sbjct: 234 YPPWFSPESKRLISKLLVVDPNKR 257
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 91.3 bits (225), Expect = 6e-18
Identities = 72/270 (26%), Positives = 117/270 (42%), Gaps = 62/270 (22%)
Query: 10 EGGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGD 69
+G +L D+Y++ + + GS+ V LA + + VA+K I DK K G
Sbjct: 49 QGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVI-----DKEKIVKSG------ 97
Query: 70 EKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNI 129
L H K IS +L R + L + +TKI
Sbjct: 98 -------------------LAGHIKREIS--ILRRVRHPYIVHLLEVMATKTKI------ 130
Query: 130 TELYDFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRD 189
YI+MEY GG+LY + + T Q++ +V + HSRG+YHRD
Sbjct: 131 ---------YIVMEYVRGGELYNTVARGRLREGTAR--RYFQQLISSVAFCHSRGVYHRD 179
Query: 190 IKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSERYMAPELFESNLDREERTD 244
+K EN+L+ N+K++D+GL+ + + + G+ Y+APE+
Sbjct: 180 LKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRK-------- 231
Query: 245 AYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
Y+ AK DIW+ G+++ ++ PF N
Sbjct: 232 GYEGAKADIWSCGVILFVLMAGYLPFDDKN 261
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 91.3 bits (225), Expect = 6e-18
Identities = 62/193 (32%), Positives = 105/193 (54%), Gaps = 28/193 (14%)
Query: 92 HQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSG 147
++K L+++ L+ NN+ E+ I ++ H NI +L++ + + ME+ G
Sbjct: 53 NKKKLLTNPALA---NNI----KREISIMRRLS-HPNIVKLHEVMATKSKIFFAMEFVKG 104
Query: 148 GDLYEAIKDDMVPRKTKNVTN-IINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLT 206
G+L+ I R +++++ Q++ AV Y H+RG+YHRD+KPEN+LI N N+K++
Sbjct: 105 GELFNKISKH--GRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVS 162
Query: 207 DWGL-ATTDKTS----MERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVML 261
D+GL A TD+ + G+ Y+APE+ Y+ AKVD+W+ GIV+
Sbjct: 163 DFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKK--------GYEGAKVDVWSCGIVLF 214
Query: 262 NIVFHKNPFTVAN 274
+V PF N
Sbjct: 215 VLVAGYLPFNDPN 227
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 91.3 bits (225), Expect = 6e-18
Identities = 71/263 (26%), Positives = 118/263 (43%), Gaps = 68/263 (25%)
Query: 15 RDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDE 74
+ R+++ + + G+YG VSLA D + + VAVK I KS
Sbjct: 72 KHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKS---------------------- 109
Query: 75 TNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYD 134
+ E K L++ ++ + +++S + H NI ++Y+
Sbjct: 110 -------AIESKADLVRIRREI---RIMSALN-------------------HPNIIQIYE 140
Query: 135 FFDS----YIIMEYCSGGDLYEAI-KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRD 189
F++ ++MEY SGG+LY+ + + +P I QI AV Y H + HRD
Sbjct: 141 VFENKDKIILVMEYSSGGELYDYVSRCGSLPEA--EARRIFRQITSAVLYCHKHRVAHRD 198
Query: 190 IKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYD 247
+K ENIL+ N N K+ D+GL+ DK + GS Y +PE+ Y
Sbjct: 199 LKLENILLDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGT--------PYK 250
Query: 248 CAKVDIWAIGIVMLNIVFHKNPF 270
+VD W++GI++ +V+ PF
Sbjct: 251 GPEVDCWSLGILLYTLVYGSMPF 273
>SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 781
Score = 90.9 bits (224), Expect = 8e-18
Identities = 63/186 (33%), Positives = 94/186 (49%), Gaps = 30/186 (16%)
Query: 125 KHKNITELYDF-FDSYI----------IMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQI 173
+H N+ + YD DS+I +M++C GDL I+D K+ +I QI
Sbjct: 509 EHPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQI 568
Query: 174 LDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATT------DKTSMERN----VG 223
L + Y+HS+GI HRDIKPENILI+ +++TD+G D T++E G
Sbjct: 569 LRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFG 628
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFC-Y 282
S+ YMAPE+ +Y+ D+W+ IV+ + F PF A+Q D+ + Y
Sbjct: 629 SDPYMAPEILTPG--------SYNAFFADMWSTAIVLHCLYFRTYPFRKASQNDQLYAKY 680
Query: 283 FAANRE 288
A RE
Sbjct: 681 CKAWRE 686
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 90.9 bits (224), Expect = 8e-18
Identities = 70/267 (26%), Positives = 122/267 (45%), Gaps = 67/267 (25%)
Query: 9 KEGGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIG 68
KE L D +++ + +G +G V LA + Q K ++A+K +FK++ +K
Sbjct: 124 KEAVALED-FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG---------- 172
Query: 69 DEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKN 128
++HQ L R EV+IQ+ + +H N
Sbjct: 173 ---------------------VEHQ--------LRR-----------EVEIQSHL-RHPN 191
Query: 129 ITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRG 184
I LY +F Y+I+EY G +Y ++ + + N+ N+I +A+ Y HS+
Sbjct: 192 ILRLYGYFHDATRVYLILEYAPLGTVYRELQK-LSKFDEQRTANLYNRIANALSYCHSKR 250
Query: 185 IYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-GSERYMAPELFESNLDREERT 243
+ HRDIKPEN+L+ +K+ D+G + +S + G+ Y+ PE+ E + E
Sbjct: 251 VIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDE--- 307
Query: 244 DAYDCAKVDIWAIGIVMLNIVFHKNPF 270
KVD+W++G++ + K PF
Sbjct: 308 ------KVDLWSLGVLCYEFLVGKPPF 328
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 90.9 bits (224), Expect = 8e-18
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 21/199 (10%)
Query: 125 KHKNITELYDFF----DSYIIMEYCSGGDLYEAI-KDDMVPRKTKNVTNIINQILDAVEY 179
+H +I LY D ++IME+ SGG+L++ I K + KT QI+ V+Y
Sbjct: 81 RHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRL--KTAEARRFFQQIISGVDY 138
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNL 237
H + HRD+KPEN+L+ N+K+ D+GL+ TD + + GS Y APE+ L
Sbjct: 139 CHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKL 198
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
Y +VD+W+ G+++ ++ PF + F + +F +
Sbjct: 199 --------YAGPEVDVWSCGVILYALLCGTLPF----DDEHVPSLFRKIKSGVFPTPDFL 246
Query: 298 SYDFFQVLRHALTIDPTNR 316
+L H L +DP R
Sbjct: 247 ERPIVNLLHHMLCVDPMKR 265
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 90.9 bits (224), Expect = 8e-18
Identities = 61/169 (36%), Positives = 90/169 (53%), Gaps = 20/169 (11%)
Query: 112 EALYEVDIQTKIGK---HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTK 164
E L +++ + KI K H +I + Y+ YI+ EYCS G+LYE + + R +
Sbjct: 55 ENLIKLEREVKIVKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEK--GRVAE 112
Query: 165 NVTNI-INQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERN 221
NV ++ AV Y+HS+GI HRD+K ENIL+ N NIK+ D+G + T +
Sbjct: 113 NVARKWFSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQTGDQLLNTW 172
Query: 222 VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
GS Y APEL N +YD K DIW++G+++ +V PF
Sbjct: 173 CGSPPYAAPELLLGN--------SYDGMKADIWSMGVLLYILVAGGFPF 213
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 90.9 bits (224), Expect = 8e-18
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 21/199 (10%)
Query: 125 KHKNITELYDFF----DSYIIMEYCSGGDLYEAI-KDDMVPRKTKNVTNIINQILDAVEY 179
+H +I LY D ++IME+ SGG+L++ I K + KT QI+ V+Y
Sbjct: 81 RHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRL--KTAEARRFFQQIISGVDY 138
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNL 237
H + HRD+KPEN+L+ N+K+ D+GL+ TD + + GS Y APE+ L
Sbjct: 139 CHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKL 198
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
Y +VD+W+ G+++ ++ PF + F + +F +
Sbjct: 199 --------YAGPEVDVWSCGVILYALLCGTLPF----DDEHVPSLFRKIKSGVFPTPDFL 246
Query: 298 SYDFFQVLRHALTIDPTNR 316
+L H L +DP R
Sbjct: 247 ERPIVNLLHHMLCVDPMKR 265
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 90.9 bits (224), Expect = 8e-18
Identities = 60/202 (29%), Positives = 95/202 (46%), Gaps = 19/202 (9%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ +H N+ LY+ D+ Y+++E GGDLY+ I + QIL A+
Sbjct: 72 KLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAI 131
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN-IKLTDWGLATT--DKTSMERNVGSERYMAPELFE 234
Y H + HRD+KPEN++ +KLTD+G + +E GS Y APE+
Sbjct: 132 TYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILL 191
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVF 294
D+YD VDIW++G+++ +V + PF AN ++ + + V
Sbjct: 192 G--------DSYDAPAVDIWSLGVILYMLVCGQAPFEKANDSET----LTMIMDCKYTVP 239
Query: 295 STMSYDFFQVLRHALTIDPTNR 316
S +S D ++ L DP R
Sbjct: 240 SHVSTDCRDLIASMLVRDPKKR 261
>YMR291w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 586
Score = 90.5 bits (223), Expect = 1e-17
Identities = 71/264 (26%), Positives = 118/264 (43%), Gaps = 47/264 (17%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H +I +L+D+F++ +I + C GDLYE I ++ VT+ ++ +E++H
Sbjct: 113 HHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLH 172
Query: 182 SRGIYHRDIKPENILIAGNWN----------------------IKLTDWGLA----TTDK 215
S+GI HRD+K EN+L N + L D+GLA T+
Sbjct: 173 SQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKV 232
Query: 216 TSMERNVGSERYMAPELF------ESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNP 269
S++ VG+ Y+APE+ E D+ + D Y C VDIWA+G++ + F P
Sbjct: 233 NSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGC-PVDIWALGVLTYFMAFGYTP 291
Query: 270 FTVANQTDKAFCYFAANREALFDVFSTMSYD-FFQVLRHALTIDPTNRNLEKVRTEIKRL 328
F + C + + Y+ F+ ++ TIDP VR K L
Sbjct: 292 FDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPA------VRRSAKNL 345
Query: 329 SEYTMDDEYY---NSLDSDEESVF 349
++ +Y+ NSL++ + F
Sbjct: 346 KQHPFIKDYFATSNSLNTKDTPNF 369
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 90.5 bits (223), Expect = 1e-17
Identities = 58/173 (33%), Positives = 89/173 (50%), Gaps = 25/173 (14%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
KH+NI LYDF + Y++MEYC+GGDL + + M + + QI A+ +
Sbjct: 71 KHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHA-MRTLSEDTIRLFLQQIAGAMRLL 129
Query: 181 HSRGIYHRDIKPENILIA---------GNWNIKLTDWGLATTDKTSMERNV--GSERYMA 229
HS+GI HRD+KP+NIL++ + +K+ D+G A +++M GS YMA
Sbjct: 130 HSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMA 189
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCY 282
PE+ S YD K D+W+IG ++ + K PF ++ D Y
Sbjct: 190 PEVIMS--------QHYD-GKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFY 233
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 90.5 bits (223), Expect = 1e-17
Identities = 58/211 (27%), Positives = 109/211 (51%), Gaps = 21/211 (9%)
Query: 125 KHKNITELY----DFFDSYIIMEYCSGGDLYEAIK-DDMVPRKTKNVTNIINQILDAVEY 179
KHKNI ++Y D Y+ E+ +GGDL+E I ++ +P V + Q++ ++Y
Sbjct: 62 KHKNIVKMYGMSMDTEFCYLFQEFVTGGDLFEKIDFENGMP--VNQVKGYLKQLMSGLKY 119
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT-----TDKTSMERNVGSERYMAPELFE 234
+H GI HRDIKP+N+LI + +K+ D+GL+T + + +G+ +MAPELF
Sbjct: 120 IHGCGIVHRDIKPDNLLINSSDALKIADFGLSTRFIVDDKEILLHERIGTTPFMAPELFA 179
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVF 294
R VDIW+ GI++ +++ P+ ++D + + N+ + ++
Sbjct: 180 KKKHRG--------PPVDIWSAGILVFSLLTGNLPWDEPKESDILYSQWMNNKTSKNCIW 231
Query: 295 STMSYDFFQVLRHALTIDPTNR-NLEKVRTE 324
+S + L+ L + R +E++ ++
Sbjct: 232 YGLSTPVVRFLKKLLKENVNERATIEEIESD 262
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 90.5 bits (223), Expect = 1e-17
Identities = 48/162 (29%), Positives = 87/162 (53%), Gaps = 19/162 (11%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
++ +H ++ L++ S Y MEY GG+L++ + + K Q++ A+
Sbjct: 65 RLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKL--KENIARKYFQQLIGAI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSERYMAPEL 232
+Y HSRG+YHRD+KPEN+L+ N ++K++D+GL+ ++ + + G+ Y+APE+
Sbjct: 123 DYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
YD AK D+W+ G+V+ ++ PF N
Sbjct: 183 IGKK--------GYDGAKADVWSCGVVLYVLLAGFLPFHEQN 216
>YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 560
Score = 90.1 bits (222), Expect = 1e-17
Identities = 60/229 (26%), Positives = 112/229 (48%), Gaps = 43/229 (18%)
Query: 78 TVNSSQEKKQRLLKH--QKSLISDKVLSRFSNNVCFEALYEVDIQT--------KIGKHK 127
T+ + Q K +L + +L++ K+L+RF + +V+ K H+
Sbjct: 55 TLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHE 114
Query: 128 NITELYDFFDS------YIIMEYCSGGDLYEAIKDDMVPRKT-------KNVTNIINQIL 174
N+ ELY+ + Y+++EYCS G + ++ M + + ++ ++
Sbjct: 115 NVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVV 174
Query: 175 DAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS------------MERNV 222
+EY+HS+GI HRDIKP N+LI+ N +K++D+G+A + T R +
Sbjct: 175 SGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRAL 234
Query: 223 GSERYMAPELFESNLDREERTDAYDCAK-VDIWAIGIVMLNIVFHKNPF 270
G+ + APEL + + Y C+ +DIW++G+ + ++F K PF
Sbjct: 235 GTPAFFAPELCSTEKE-------YSCSSAIDIWSLGVTIYCLLFGKLPF 276
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 90.1 bits (222), Expect = 1e-17
Identities = 68/212 (32%), Positives = 111/212 (52%), Gaps = 25/212 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ + KI KH+NI L D ++S Y++M+ SGG+L++ I + V + K+ + +I
Sbjct: 68 EIAVLKKI-KHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTE-KDASLVIQ 125
Query: 172 QILDAVEYVHSRGIYHRDIKPENILI---AGNWNIKLTDWGLATTDKTS-MERNVGSERY 227
Q+L AV+Y+H GI HRD+KPEN+L N I +TD+GL+ ++ M G+ Y
Sbjct: 126 QVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGY 185
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF---TVANQTDKAFCYFA 284
+APE+ L ++ + A DC W+IG++ ++ PF T + +K +
Sbjct: 186 VAPEV----LAQKPYSKAVDC-----WSIGVITYILLCGYPPFYEETESKLFEKIKEGYY 236
Query: 285 ANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+D S + DF + H L DP R
Sbjct: 237 EFESPFWDDISESAKDF---ICHLLEKDPNER 265
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 90.1 bits (222), Expect = 1e-17
Identities = 62/215 (28%), Positives = 113/215 (51%), Gaps = 25/215 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVT--NI 169
E++IQ+ + H NI +LY +F Y+++EY GG++Y+ + V ++ T
Sbjct: 78 EIEIQSHLN-HPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLT---VSKRFSEPTAAKY 133
Query: 170 INQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-GSERYM 228
+ +I DA+ Y H + + HRDIKPEN+LI +K+ D+G + ++ + + G+ Y+
Sbjct: 134 MYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYL 193
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANRE 288
PE+ ++ + +DA VD+WAIG++ + K PF +Q+ +AA +
Sbjct: 194 PPEM----VNGADHSDA-----VDLWAIGVLCYEFLVGKPPFEHEDQSKT----YAAIKA 240
Query: 289 ALFDVFSTMSYDFFQVLRHALTIDPTNR-NLEKVR 322
A F ++ ++ L +DP R LE+V+
Sbjct: 241 ARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVK 275
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 90.1 bits (222), Expect = 1e-17
Identities = 58/204 (28%), Positives = 102/204 (49%), Gaps = 23/204 (11%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ +H NI EL + + + +ME+ GG+L+ I + Q++ AV
Sbjct: 66 KLVRHPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAAR--RYFQQLISAV 123
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-----GSERYMAPEL 232
+Y HSRG+ HRD+KPEN+L+ N ++K++D+GL+ + ++ + G+ Y+APE+
Sbjct: 124 DYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEV 183
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ YD AK DIW+ G+V+ ++ PF N + F A+ F+
Sbjct: 184 LKKK--------GYDGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRAD----FE 231
Query: 293 VFSTMSYDFFQVLRHALTIDPTNR 316
S + +++ L +DP R
Sbjct: 232 FPPWFSPEARRLISKLLVVDPDRR 255
>7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1726
Score = 90.1 bits (222), Expect = 1e-17
Identities = 62/233 (26%), Positives = 114/233 (48%), Gaps = 13/233 (5%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCS 146
K QK + K+ + + E+DI ++I KH NI ELY+ F ++++EYC
Sbjct: 57 KEQKRFAAAKMCQLEDEENLSDHMVEIDILSEI-KHPNIVELYEAFSIDDKLWMLIEYCD 115
Query: 147 GGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLT 206
GG L + + P + + + + + ++H + HRD+K N+L+ +KL
Sbjct: 116 GGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLA 175
Query: 207 DWGLATTDKTSMERN---VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNI 263
D+G++ +K +M+++ +G+ +MAPEL L R + YD KVDIW++GI ++ +
Sbjct: 176 DFGVSAKNKHTMQKHDTFIGTPYWMAPELV---LCETFRDNPYD-HKVDIWSLGITLIEL 231
Query: 264 VFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ P + + + + + S S +F L+ +L DP R
Sbjct: 232 AQMEPPNSEMSPM-RVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVR 283
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 90.1 bits (222), Expect = 1e-17
Identities = 58/208 (27%), Positives = 103/208 (48%), Gaps = 20/208 (9%)
Query: 122 KIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ +H +I +LY D ++IMEY SGG+L++ I ++ + QI+ V
Sbjct: 81 KLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQ-ARRFFQQIISGV 139
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFES 235
+Y H I HRD+KPEN+L+ N ++K+ D+GL+ D + + GS Y APE+
Sbjct: 140 DYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISG 199
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFS 295
L Y +VDIW+ G+++ ++ PF + F + +F +
Sbjct: 200 KL--------YAGPEVDIWSCGVILYALLCGTLPF----DDEHVPTLFRKIKSGIFPIPE 247
Query: 296 TMSYDFFQVLRHALTIDPTNR-NLEKVR 322
++ ++ L +DP R N+E+++
Sbjct: 248 YLNKQVVNLVCQMLQVDPLKRANIEEIK 275
>YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 1142
Score = 89.7 bits (221), Expect = 2e-17
Identities = 74/308 (24%), Positives = 134/308 (43%), Gaps = 83/308 (26%)
Query: 1 MTLDYEVYKEGGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDT 60
++L Y+ + +L + Y++I+++ G +G V LA D K+LVA+K + + E
Sbjct: 117 ISLTYDPVSKRKVL-NTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHE------- 168
Query: 61 KDGVMVIGDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQ 120
Q K +K K +DK+ E+ I
Sbjct: 169 --------------------KKQRKFFTFIKSSKISENDKIKR------------EIAIM 196
Query: 121 TKIGKHKNITELYDFFDS------YIIMEYCSGGDLYEAIKDDMVPRKT-------KNVT 167
K HK++ +L + D Y+++EYCS G++ D M +
Sbjct: 197 KKC-HHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETR 255
Query: 168 NIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA-------------TTD 214
I+ ++ +EY+H +GI HRDIKP N+LI+G+ +K++D+G++ + D
Sbjct: 256 EILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLD 315
Query: 215 KTSMERNVGSERYMAPELFESNLDREERTDAYDCAK------------VDIWAIGIVMLN 262
+ + + VG+ + APE+ E+ Y+ K +DIWA+G+ +
Sbjct: 316 ELELAKTVGTPAFFAPEMCLG----EDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYC 371
Query: 263 IVFHKNPF 270
++F PF
Sbjct: 372 LLFGMLPF 379
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 89.7 bits (221), Expect = 2e-17
Identities = 60/198 (30%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 90 LKHQKSLISDKVLSRFSNNVCFEALY-----EVDIQTKIGKHKNITELYDFFDS----YI 140
LK +++ KVL F + + E L E++IQ + +H NI LY++F Y+
Sbjct: 28 LKESHFIVALKVL--FKSQIEKEGLEHQLRREIEIQAHL-QHPNILRLYNYFHDARRVYL 84
Query: 141 IMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGN 200
I+EY G+LY+ ++ + + T II ++ DA+ Y H + + HRDIKPEN+L+
Sbjct: 85 ILEYAPRGELYKELQKSEKLDEQRTAT-IIEEVADALTYCHDKKVIHRDIKPENLLLGFR 143
Query: 201 WNIKLTDWGLAT-TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIV 259
+K+ D+G + T + G+ Y+ PE+ E YD KVD+W IG++
Sbjct: 144 GEVKIADFGWSVHTPLPERKTMCGTLDYLPPEMIEGR--------TYD-EKVDLWCIGVL 194
Query: 260 MLNIVFHKNPFTVANQTD 277
++ PF A+ ++
Sbjct: 195 CYELLVGYPPFESASHSE 212
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 89.7 bits (221), Expect = 2e-17
Identities = 59/237 (24%), Positives = 126/237 (52%), Gaps = 27/237 (11%)
Query: 97 ISDKVLSR--FSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDL 150
++ K+++R S +V + E+ I K+ +H ++ +L+D +++ Y+++E+ SGG+L
Sbjct: 77 VAIKIVNREKLSESVLMKVEREIAI-LKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGEL 135
Query: 151 YEAI--KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDW 208
++ + K + P++ + QI+ A+++ HS I HRD+KPEN+L+ NI++ D+
Sbjct: 136 FDYLVKKGRLTPKEARK---FFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADF 192
Query: 209 GLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFH 266
G+A+ + +E + GS Y PE+ + + YD + D+W+ G+++ ++
Sbjct: 193 GMASLQVGDSLLETSCGSPHYACPEVIKG--------EKYDGRRADMWSCGVILFALLVG 244
Query: 267 KNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR-NLEKVR 322
PF D + +F + + D +LR + ++P R +LE+++
Sbjct: 245 ALPF----DDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQ 297
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 89.7 bits (221), Expect = 2e-17
Identities = 67/236 (28%), Positives = 111/236 (46%), Gaps = 26/236 (11%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
KH NI EL++ S Y ME GG+L+ + + V Q++ AV++
Sbjct: 80 KHPNIVELHEVMASKSKIYFAMELVRGGELFAKVAKGRLREDVARV--YFQQLISAVDFC 137
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGL-ATTDKTS----MERNVGSERYMAPELFES 235
HSRG+YHRD+KPEN+L+ N+K+TD+GL A T+ + G+ Y+APE+
Sbjct: 138 HSRGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILK 197
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFS 295
YD AK D+W+ G+++ ++ PF Q D + F
Sbjct: 198 K--------GYDGAKADLWSCGVILFVLLAGYLPF----QDDNLVNMYRKIYRGDFKCPG 245
Query: 296 TMSYDFFQVLRHALTIDPTNR-NLEKVRTE--IKRLSEYTMDDEYYNSLDSDEESV 348
+S D +++ L +P R +EKV K+ + + ++ ++ + EE V
Sbjct: 246 WLSSDARRLVTKLLDPNPNTRITIEKVMDSPWFKKQATRSRNEPVAATITTTEEDV 301
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 89.7 bits (221), Expect = 2e-17
Identities = 55/171 (32%), Positives = 87/171 (50%), Gaps = 17/171 (9%)
Query: 107 NNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYE-AIKDDMVPR 161
N + LY K+ H NI L+ +S Y++MEY S G+L++ +K+ +
Sbjct: 135 NTSARQKLYREVKIMKLLNHPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRE 194
Query: 162 KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATT--DKTSME 219
+ V I Q++ A++Y HS+ + HRD+K EN+L+ + NIK+ D+G T +E
Sbjct: 195 RDARV--IFRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFGNTFDPNAQLE 252
Query: 220 RNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
GS Y APELF Y +VD W++G+V+ +V PF
Sbjct: 253 TFCGSPPYAAPELFMGR--------KYAGPEVDAWSLGVVLYTLVSGSLPF 295
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 89.4 bits (220), Expect = 2e-17
Identities = 78/318 (24%), Positives = 143/318 (44%), Gaps = 73/318 (22%)
Query: 15 RDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDE 74
R YK++E + +GS+G V L +L + +VK K G K
Sbjct: 340 RKEYKVVEHLCKGSFGQVHLC---ELTRNPSVKVAVKEVAVSGKSRK------------- 383
Query: 75 TNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYD 134
N T + K R L +KIG H+N+ ++
Sbjct: 384 -NLTAVQKEYKIHRRL------------------------------SKIG-HENVIQMMK 411
Query: 135 FFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDI 190
++ ++MEY GGDL++ +K+ + K+ + Q++ ++++H +GI HRDI
Sbjct: 412 MIETPKFYSLVMEYADGGDLFDELKEQEKFSR-KDAHSYFKQLIKGLKFIHEQGIVHRDI 470
Query: 191 KPENILIAGN------WNIKLTDWGLATT-----DKTSMERNVGSERYMAPELFESNLDR 239
K EN+L+ + +K+TD+GLAT ++ + + GS+ Y APE+ N
Sbjct: 471 KLENLLLVYSESEDDPGTLKITDFGLATKYRKDGEEIMLSEDCGSKPYAAPEVCTGN--- 527
Query: 240 EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN-QTDKAFCYFAANREALFDVFSTMS 298
Y VDIW+ G+V++ ++ ++ + VAN + D A+ + ++ ++++ +S
Sbjct: 528 -----DYRGPPVDIWSAGVVLMTMLVGEHSWKVANKEKDAAYSNWINAKDEKANLWNVIS 582
Query: 299 YDFFQVLRHALTIDPTNR 316
+LR L +P R
Sbjct: 583 GPTTALLRKLLHANPEKR 600
Score = 82.8 bits (203), Expect = 2e-15
Identities = 63/226 (27%), Positives = 105/226 (45%), Gaps = 27/226 (11%)
Query: 100 KVLSRFSNNVCF--EALYEVDIQTKIGK--HKNITELYDFFDS----YIIMEYCSGGDLY 151
K +S + CF E IQ ++ K H N+ L++ + +I+ Y GGDL+
Sbjct: 48 KEISIVGKDECFMESIKRECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLF 107
Query: 152 EAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA 211
E I + Q++D + ++H G+ HRDIKPEN+L+ + +K+ D+G A
Sbjct: 108 EKINQHG-GLGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFA 166
Query: 212 TTDKTS-----MERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFH 266
T + + + GS Y+APE+ + +D Y VDIW+ G+V++ ++
Sbjct: 167 TMHRFNGAEQMLNAYCGSPPYIAPEVL-TGID-------YRGPAVDIWSAGVVLIAMIAG 218
Query: 267 KNPFTVANQTD---KAFCYFAANREALFDVFSTMSYDFFQVLRHAL 309
P+ A+ D +C F N +S MS +LR L
Sbjct: 219 AVPWEQADHFDIFQSRYCSFRRNGRK--GAWSRMSQQVISLLRKIL 262
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 89.0 bits (219), Expect = 3e-17
Identities = 68/267 (25%), Positives = 122/267 (45%), Gaps = 66/267 (24%)
Query: 16 DRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDET 75
D +++ + +G +G V LA + + +VA+K +FKS+ +K +GV
Sbjct: 75 DDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEK-----EGV----------- 118
Query: 76 NNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF 135
+HQ L R E++IQ + H NI LY++
Sbjct: 119 ---------------EHQ--------LRR-----------EIEIQAHL-HHPNILRLYNY 143
Query: 136 FDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIK 191
F Y+I+EY G+LY+ ++ + + T I+ ++ DA+ Y H + + HRDIK
Sbjct: 144 FYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTAT-IMEELADALMYCHGKKVIHRDIK 202
Query: 192 PENILIAGNWNIKLTDWGLATTDKTSMERNV-GSERYMAPELFESNLDREERTDAYDCAK 250
PEN+L+ +K+ D+G + + + + G+ Y+ PE+ E + E K
Sbjct: 203 PENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNE---------K 253
Query: 251 VDIWAIGIVMLNIVFHKNPFTVANQTD 277
VD+W IG++ ++ PF A+ +
Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNE 280
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 89.0 bits (219), Expect = 3e-17
Identities = 62/213 (29%), Positives = 103/213 (48%), Gaps = 19/213 (8%)
Query: 110 CFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKN 165
C + ++ I + + H +I L +F S ++I EY G LY+ I P K K
Sbjct: 105 CDQRVFREVIISSVLNHPHIARLKNFLYSPTHYFLIFEYVKGRQLYDIIISSG-PLKEKE 163
Query: 166 VTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVG 223
Q+L A++Y+H + HRD+K ENILI N N+KL D+GL+ +KT + G
Sbjct: 164 GQRYFRQLLSAIDYIHRNSVVHRDLKIENILIDENDNVKLIDFGLSNFYDNKTLLNTFCG 223
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYF 283
S + APEL + Y ++D+W++G+V+ I+ PF +
Sbjct: 224 SLYFAAPELLQG--------QRYCGPEIDVWSLGVVLYAILCGCVPF----DDEDVQGLQ 271
Query: 284 AANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
A +A F T+S + +++R + P++R
Sbjct: 272 AKIMDADFKFCKTISREAMELIRGMIVAQPSSR 304
>7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 520
Score = 89.0 bits (219), Expect = 3e-17
Identities = 75/250 (30%), Positives = 125/250 (50%), Gaps = 29/250 (11%)
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF- 136
TV ++ KKQR H + LS+ S + E+ + ++ KHK I L DFF
Sbjct: 22 TVYKARHKKQRTY-HAIKYVEMSTLSQTSRE---NLITEIRLLREL-KHKYIVTLQDFFW 76
Query: 137 ---DSYIIMEYCSGGDLYEAIKDDM-VPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKP 192
+ YI++EYC+ G+L I+ +P T + Q+ AV+Y+ + + H D+KP
Sbjct: 77 DDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRY--FLRQLAAAVQYMRANDVSHFDLKP 134
Query: 193 ENILI---AGNWNIKLTDWGLATTDKTS--MERNVGSERYMAPELFESNLDREERTDAYD 247
+N+L+ A N ++K+ D+G A K ++ GS YMAPE+ R YD
Sbjct: 135 QNLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIV--------RKHQYD 186
Query: 248 CAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREAL-FDVFSTMSYDFFQVLR 306
AK D+W+IG+++ +F K P+ +++T + EA+ + +S + +LR
Sbjct: 187 -AKADLWSIGVILYECLFGKAPY--SSRTIEELLLRIRKAEAITLPPNARISNECHDLLR 243
Query: 307 HALTIDPTNR 316
L +PT R
Sbjct: 244 RLLAHEPTAR 253
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 88.6 bits (218), Expect = 4e-17
Identities = 69/247 (27%), Positives = 118/247 (46%), Gaps = 24/247 (9%)
Query: 82 SQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALY-EVDIQTKIGKHKNITELYDFFDS-- 138
S + K+ LK Q+ + S+ ++ + E + EV I + H+N+ + YD F+
Sbjct: 160 SAKFKKGELKDQEVAVKVIPKSKMTSAISIEDVRREVKILRALSGHQNLVQFYDAFEDNA 219
Query: 139 --YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
YI+ME C GG+L + I + ++ QIL+ V + H +G+ HRD+KPEN L
Sbjct: 220 NVYIVMELCGGGELLDRILARGGKYSEDDAKAVLIQILNVVAFCHLQGVVHRDLKPENFL 279
Query: 197 IAG---NWNIKLTDWGLATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKV 251
N +K+ D+GL+ + N VGS Y+APE+ L R T+A
Sbjct: 280 YTSKEENSMLKVIDFGLSDFVRPDERLNDIVGSAYYVAPEV----LHRSYTTEA------ 329
Query: 252 DIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD--VFSTMSYDFFQVLRHAL 309
D+W+IG++ ++ PF +T+ + FD + ++S++ ++ L
Sbjct: 330 DVWSIGVIAYILLCGSRPFWA--RTESGIFRAVLKADPSFDEPPWPSLSFEAKDFVKRLL 387
Query: 310 TIDPTNR 316
DP R
Sbjct: 388 YKDPRKR 394
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 88.6 bits (218), Expect = 4e-17
Identities = 77/335 (22%), Positives = 140/335 (40%), Gaps = 68/335 (20%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYI-FKSEDDKGNDTKDGVMVIGDEKDDETN 76
+ L + + EG+YG V L + Q + VA+K + K D N + V +
Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCI---------- 71
Query: 77 NTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF 136
+ ++ DK + RF GK +
Sbjct: 72 -----------------QKMLQDKHILRF-----------------FGKRSQGSV----- 92
Query: 137 DSYIIMEYCSGGDLYEAIKDDM-VPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENI 195
YI +EY +GG+L++ I ++ V Q+L + Y+H RGI HRD+KPEN+
Sbjct: 93 -EYIFLEYAAGGELFDRIGEEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENL 151
Query: 196 LIAGNWNIKLTDWGLATTDKTS-----MERNVGSERYMAPELFESNLDREERTDAYDCAK 250
L+ + N+K++D+G+AT + +++ G+ Y+APE+ + AY
Sbjct: 152 LLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQK---------AYHAQP 202
Query: 251 VDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANRE-ALFDVFSTMSYDFFQVLRHAL 309
D+W+ G++++ ++ + P+ + F + N L +S + +LR L
Sbjct: 203 ADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLL 262
Query: 310 TIDP-TNRNLEKVRTEIKRLSEYTMDDEYYNSLDS 343
P T LEK ++ ++ Y+ +DS
Sbjct: 263 ATSPGTRLTLEKTLDHKWCNMQFADNERSYDLVDS 297
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 88.2 bits (217), Expect = 5e-17
Identities = 71/260 (27%), Positives = 119/260 (45%), Gaps = 69/260 (26%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
Y + E + EGS+G V LA+ + ++ VA+K+I
Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFI---------------------------- 65
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF- 136
+Q L K + ++ +S K+ +H +I +LYD
Sbjct: 66 -------SRQLLKKSDMHMRVEREISYL----------------KLLRHPHIIKLYDVIT 102
Query: 137 ---DSYIIMEYCSGGDLYEAIKDDMVPRKTKNV-TNIINQILDAVEYVHSRGIYHRDIKP 192
D +++EY +GG+L++ I + R T++ QI+ A+EY H I HRD+KP
Sbjct: 103 TPTDIVMVIEY-AGGELFDYIVEKK--RMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKP 159
Query: 193 ENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAK 250
EN+L+ N N+K+ D+GL+ TD ++ + GS Y APE+ L Y +
Sbjct: 160 ENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKL--------YAGPE 211
Query: 251 VDIWAIGIVMLNIVFHKNPF 270
VD+W+ GIV+ ++ + PF
Sbjct: 212 VDVWSCGIVLYVMLVGRLPF 231
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 88.2 bits (217), Expect = 5e-17
Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 10/209 (4%)
Query: 114 LYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNI 169
L EVDI K+ H NI +L D +++ +++ + G+L++ + + V K I
Sbjct: 72 LKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEK-VTLSEKETRKI 130
Query: 170 INQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS--MERNVGSERY 227
+ +L+ + +H I HRD+KPENIL+ N NIKLTD+G + + + G+ Y
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSY 190
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANR 287
+APE+ E +++ + Y +VD+W+ G++M ++ PF Q + N
Sbjct: 191 LAPEIIECSMNEDH--PGYG-KEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNY 247
Query: 288 EALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ + S ++ L + P NR
Sbjct: 248 QFGSPEWDDYSDTVKDLVSRFLVVQPQNR 276
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 88.2 bits (217), Expect = 5e-17
Identities = 59/213 (27%), Positives = 102/213 (47%), Gaps = 26/213 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPR---KTKNVTN 168
EV+I + KH NI + F+ Y++ME C GG+L++ I V R + +
Sbjct: 114 EVEIMRCLPKHPNIVSFKEAFEDKDAVYLVMEICEGGELFDRI----VSRGHYTERAAAS 169
Query: 169 IINQILDAVEYVHSRGIYHRDIKPENILIAGNW---NIKLTDWGLATTDKTSMERN--VG 223
+ IL+ V+ H G+ HRD+KPEN L + +K D+GL+ K + N VG
Sbjct: 170 VAKTILEVVKVCHEHGVIHRDLKPENFLFSNGTETAQLKAIDFGLSIFFKPAQRFNEIVG 229
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYF 283
S YMAPE+ N E +D+W+ G+++ ++ PF + A
Sbjct: 230 SPYYMAPEVLRRNYGPE----------IDVWSAGVILYILLCGVPPFWAETEEGIAHAIV 279
Query: 284 AANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
N + D + +S++ +++++ L +P +R
Sbjct: 280 RGNIDFERDPWPKVSHEAKELVKNMLDANPYSR 312
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 88.2 bits (217), Expect = 5e-17
Identities = 75/310 (24%), Positives = 133/310 (42%), Gaps = 74/310 (23%)
Query: 15 RDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDE 74
R+RYK +++ +G+ G V +A+D Q + VAVK I D K +KD +
Sbjct: 290 RERYKTTQEVGKGASGIVFIAADLQNESQVAVKTI----DMKNQSSKDLI---------- 335
Query: 75 TNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYD 134
L +VL F+ HKN+ D
Sbjct: 336 ---------------------LTEIRVLKDFN-------------------HKNLVNFLD 355
Query: 135 FF------DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHR 188
+ +++MEY GG L + + + ++ K + + + + L A+ ++H++GI HR
Sbjct: 356 AYLLEPEDQLWVVMEYMDGGPLTDVVTETVM--KERQIACVCRETLYAISFLHAKGIIHR 413
Query: 189 DIKPENILIAGNWNIKLTDWGLATTDKTSMERN--VGSERYMAPELFESNLDREERTDAY 246
DIK +N+L+ + ++K+TD+G + +R VG+ +MAPE+ T
Sbjct: 414 DIKSDNVLLGMDGSVKVTDFGFCANIEGDEKRQTMVGTPYWMAPEVV---------TRKK 464
Query: 247 DCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLR 306
KVDIW+IGI+ + ++ + P+ +A AAN + +S + L
Sbjct: 465 YGKKVDIWSIGIMAIEMIEGQPPYLYETPL-RALYLIAANGRPDIKSWDKLSPNLQDFLD 523
Query: 307 HALTIDPTNR 316
L ++ R
Sbjct: 524 RCLQVEVDRR 533
>CE20636 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 687
Score = 87.8 bits (216), Expect = 6e-17
Identities = 47/141 (33%), Positives = 81/141 (57%), Gaps = 16/141 (11%)
Query: 139 YIIMEYCSGGDLYEAIKDDMVPRKTKNVTN-IINQILDAVEYVHSRGIYHRDIKPENILI 197
++IMEY GGDL++ I + R T + + Q++ + Y+HS+G+ HRDIKPEN+++
Sbjct: 409 FLIMEYADGGDLFDKISSEY--RLTSSQAHGYFKQLIAGLRYIHSKGVTHRDIKPENLML 466
Query: 198 AGNWNIKLTDWGLATT-----DKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVD 252
+K+TD+GL T +++ M+ G+ +Y APE+ N Y VD
Sbjct: 467 TKAGVLKITDFGLGTLHIIKGEESLMDTRCGTPQYAAPEVLVGN--------QYRGPPVD 518
Query: 253 IWAIGIVMLNIVFHKNPFTVA 273
IW+ G+V++N++ +P+ A
Sbjct: 519 IWSAGVVLINMLTGHSPWKKA 539
Score = 79.0 bits (193), Expect = 3e-14
Identities = 74/324 (22%), Positives = 145/324 (43%), Gaps = 74/324 (22%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
Y ++ +SEG+YG VSL E K D K V I
Sbjct: 21 YNVVRFLSEGTYGQVSLY-----------------ESSKNPDVKIAVKQI---------- 53
Query: 78 TVNSSQEKKQRLLKHQKSLIS-DKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF- 135
S+ + +R ++H K+ + K LS KIG H+N+ + +
Sbjct: 54 ---STAGQSERFVEHIKTEFAIHKGLS------------------KIGGHRNVISMMEMR 92
Query: 136 --FDSYIIM-EYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKP 192
D Y ++ EY GGDL++ ++ + + ++N Q++ ++++H I HRDIK
Sbjct: 93 KGSDCYTLLKEYADGGDLFKKLETEG-EQYSENAQCFFKQLISGLKFIHEHEIVHRDIKL 151
Query: 193 ENILIAGNWN------IKLTDWGLATT-----DKTSMERNVGSERYMAPELFESNLDREE 241
EN+L+ + + +K+ D+GLAT ++ + N GS Y APE++ R
Sbjct: 152 ENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAAPEVYSKQGHRGP 211
Query: 242 RTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDF 301
T D+W+ G++++ ++ P+ A++ D + + + ++++ +S
Sbjct: 212 PT--------DVWSSGVILMAMLTAGLPWDCAHRKDVDYAAWIDKKFRTDNLWNDISDRA 263
Query: 302 FQVLRHALTIDPTNR-NLEKVRTE 324
+LR L ++ + R ++E++ +
Sbjct: 264 LALLRKILCVNVSERVSIEQIEAD 287
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 87.8 bits (216), Expect = 6e-17
Identities = 55/197 (27%), Positives = 96/197 (47%), Gaps = 19/197 (9%)
Query: 126 HKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H +I Y+ D Y++MEY G+L++ I + ++ + N QI+ VEY H
Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDE-ARNFFQQIISGVEYCH 135
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLATT--DKTSMERNVGSERYMAPELFESNLDR 239
+ HRD+KPEN+L+ NIK+ D+GL+ D ++ + GS Y APE+ L
Sbjct: 136 RNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKL-- 193
Query: 240 EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSY 299
Y +VD+W+ G+++ ++ PF N + F + ++ + S +S
Sbjct: 194 ------YAGPEVDVWSCGVILYALLCGTLPFDDENIPN----LFKKIKGGIYTLPSHLSS 243
Query: 300 DFFQVLRHALTIDPTNR 316
+ ++ L +DP R
Sbjct: 244 EARDLIPRMLIVDPVKR 260
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 87.8 bits (216), Expect = 6e-17
Identities = 55/197 (27%), Positives = 97/197 (48%), Gaps = 19/197 (9%)
Query: 126 HKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H +I LY+ D Y++MEY + G+L++ I + ++ + N QI+ VEY H
Sbjct: 76 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDE-ARNFFQQIISGVEYCH 134
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDR 239
+ HRD+KPEN+L+ N+K+ D+GL+ D ++ + GS Y APE+ L
Sbjct: 135 RNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKL-- 192
Query: 240 EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSY 299
Y +VD+W+ G+++ ++ PF N + F + ++ + S +S
Sbjct: 193 ------YAGPEVDVWSCGVILYALLCGTLPFDDENIPN----LFKKIKGGIYTLPSHLSP 242
Query: 300 DFFQVLRHALTIDPTNR 316
++ L +DP R
Sbjct: 243 GARDLIPRMLVVDPMKR 259
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 87.4 bits (215), Expect = 8e-17
Identities = 70/229 (30%), Positives = 111/229 (47%), Gaps = 21/229 (9%)
Query: 97 ISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYE 152
+ DK ++ V E IQ I +H NIT+L D ++ Y++ME C GG+L
Sbjct: 92 VIDKKRAKKDTYVTKNLRREGQIQQMI-RHPNITQLLDILETENSYYLVMELCPGGNLMH 150
Query: 153 AIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT 212
I + +++ I Q++ AVE++H G+ HRD+K EN+L+ + NIKL D+GL+
Sbjct: 151 KIYEKKRLEESE-ARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSN 209
Query: 213 TD-----KTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHK 267
GS Y APEL L R++ K+D+W+IG+ M ++
Sbjct: 210 CAGILGYSDPFSTQCGSPAYAAPEL----LARKKYG-----PKIDVWSIGVNMYAMLTGT 260
Query: 268 NPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
PFTV + +A ++E + + + +S LR L DP R
Sbjct: 261 LPFTVEPFSLRALYQKMVDKE-MNPLPTQLSTGAISFLRSLLEPDPVKR 308
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 87.4 bits (215), Expect = 8e-17
Identities = 52/158 (32%), Positives = 88/158 (54%), Gaps = 18/158 (11%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ H+N+ + Y Y+ +EYCSGG+L++ I+ D + + +Q++ V
Sbjct: 60 KMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPD-IGMPEPDAQRFFHQLMAGV 118
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS-----MERNVGSERYMAPEL 232
Y+H GI HRDIKPEN+L+ N+K++D+GLAT + + + + G+ Y+APEL
Sbjct: 119 VYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPEL 178
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
L R E + VD+W+ GIV+ ++ + P+
Sbjct: 179 ----LKRRE----FHAEPVDVWSCGIVLTAMLAGELPW 208
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 87.4 bits (215), Expect = 8e-17
Identities = 56/182 (30%), Positives = 93/182 (50%), Gaps = 17/182 (9%)
Query: 100 KVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAI- 154
+V R CF EV++ + I +H +I + D F + +I+ E+ GDLYE I
Sbjct: 104 QVEKRAMRGKCFFVDNEVEMLSLI-QHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIR 162
Query: 155 KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTD 214
K+ + + + Q+ A+ Y+H R + HRD+KPEN+L+ +++KL D+GLA
Sbjct: 163 KNGRIEEPDAAIITL--QVASALNYLHERNVVHRDVKPENLLLVDKFSVKLCDFGLACHI 220
Query: 215 KTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
+ R G+ Y APE+ R Y + DIW++G+V+ ++ PF +
Sbjct: 221 LGPLYRICGTPTYCAPEVL--------RETGYS-TRCDIWSLGVVLYVMLVGYAPFRAPD 271
Query: 275 QT 276
QT
Sbjct: 272 QT 273
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 87.0 bits (214), Expect = 1e-16
Identities = 69/233 (29%), Positives = 115/233 (48%), Gaps = 26/233 (11%)
Query: 94 KSLISDKVLSRFS-NNVCFEALY-EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSG 147
K+ ++ K++ + + V E +Y EV I K+ H +I +LY ++ Y++ EY
Sbjct: 43 KTEVAIKIIDKSQLDAVNLEKIYREVQIM-KMLDHPHIIKLYQVMETKSMLYLVTEYAKN 101
Query: 148 GDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTD 207
G++++ + + +++ QIL AV+Y H R I HRD+K EN+L+ N NIK+ D
Sbjct: 102 GEIFDYLANHGRLNESE-ARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIAD 160
Query: 208 WGLATTDKTS--MERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVF 265
+G K+ + GS Y APE+FE Y+ ++DIW++G+V+ +V
Sbjct: 161 FGFGNFFKSGELLATWCGSPPYAAPEVFEG--------QQYEGPQLDIWSMGVVLYVLVC 212
Query: 266 HKNPFTVANQTDKAFCYFAANR--EALFDVFSTMSYDFFQVLRHALTIDPTNR 316
PF D R E F + MS D ++R L +DP+ R
Sbjct: 213 GALPF------DGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKR 259
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 87.0 bits (214), Expect = 1e-16
Identities = 46/159 (28%), Positives = 83/159 (51%), Gaps = 19/159 (11%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
+H NI EL++ + Y +ME+ GG+L+ + + Q++ AV++
Sbjct: 68 RHPNIVELHEVMATKSKIYFVMEHVKGGELFNKVSTGKLREDVAR--KYFQQLVRAVDFC 125
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS-----MERNVGSERYMAPELFES 235
HSRG+ HRD+KPEN+L+ + N+K++D+GL+ + + G+ Y+APE+
Sbjct: 126 HSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISR 185
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
N YD K D+W+ G+++ ++ PF +N
Sbjct: 186 N--------GYDGFKADVWSCGVILFVLLAGYLPFRDSN 216
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 87.0 bits (214), Expect = 1e-16
Identities = 53/161 (32%), Positives = 92/161 (56%), Gaps = 17/161 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS---YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQ 172
E++I K+ KH+NI E+ D F++ + ++ + G+L+E ++DD + + V I Q
Sbjct: 53 EIEILRKL-KHENIIEMLDSFENAREFCVVTEFAQGELFEILEDDKCLPE-EQVQAIAKQ 110
Query: 173 ILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGSERYMA 229
++ A++Y+HS I HRD+KP+NILI +KL D+G A +T+ + G+ YMA
Sbjct: 111 LVKALDYLHSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMA 170
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
PEL + YD VD+W++G+++ + + PF
Sbjct: 171 PELV--------KEQPYD-RTVDLWSLGVILYELYVGQPPF 202
>YLR362w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 717
Score = 86.7 bits (213), Expect = 1e-16
Identities = 70/267 (26%), Positives = 124/267 (46%), Gaps = 30/267 (11%)
Query: 24 ISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNTVNSSQ 83
I GS+G V L + +L+AVK + + K+ + + + + + N+ N+ Q
Sbjct: 421 IGSGSFGSVYLGMNAHTGELMAVKQV---------EIKNNNIGVPTDNNKQANSDENNEQ 471
Query: 84 EKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----Y 139
E++Q ++ ++ K + +E+++ ++ H+NI Y
Sbjct: 472 EEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKEL-HHENIVTYYGASQEGGNLN 530
Query: 140 IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG 199
I +EY GG + ++ ++ P + +TN QIL V Y+H + I HRDIK NILI
Sbjct: 531 IFLEYVPGGSV-SSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDI 589
Query: 200 NWNIKLTDWG----LATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKVDI 253
+K+TD+G L+ +K +R GS +M+PE+ + AK DI
Sbjct: 590 KGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTA---------TTAKADI 640
Query: 254 WAIGIVMLNIVFHKNPFTVANQTDKAF 280
W+ G V++ + K+PF +Q F
Sbjct: 641 WSTGCVVIEMFTGKHPFPDFSQMQAIF 667
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 86.7 bits (213), Expect = 1e-16
Identities = 68/261 (26%), Positives = 115/261 (44%), Gaps = 71/261 (27%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
Y++++ + EGS+G V LA T + VA+K I K
Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINK-------------------------- 88
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
K L + R + + L +H +I +LYD
Sbjct: 89 ----------------KVLAKSDMQGRIEREISYLRLL---------RHPHIIKLYDVIK 123
Query: 138 S----YIIMEYCSGGDLYEAI--KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIK 191
S +++EY +G +L++ I +D M ++ + QI+ AVEY H I HRD+K
Sbjct: 124 SKDEIIMVIEY-AGNELFDYIVQRDKMSEQEARR---FFQQIISAVEYCHRHKIVHRDLK 179
Query: 192 PENILIAGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCA 249
PEN+L+ + N+K+ D+GL+ TD ++ + GS Y APE+ L Y
Sbjct: 180 PENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKL--------YAGP 231
Query: 250 KVDIWAIGIVMLNIVFHKNPF 270
+VD+W+ G+++ ++ + PF
Sbjct: 232 EVDVWSCGVILYVMLCRRLPF 252
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 86.7 bits (213), Expect = 1e-16
Identities = 71/263 (26%), Positives = 116/263 (43%), Gaps = 67/263 (25%)
Query: 14 LRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDD 73
LR RY+ +E + +G+YG V A ++ +LVA+K I K + I DE+D
Sbjct: 49 LRHRYEFLETLGKGTYGKVKKARESS-GRLVAIKSIRKDK-------------IKDEQD- 93
Query: 74 ETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELY 133
L H + E++I + + H +I ++
Sbjct: 94 ----------------LMHIRR--------------------EIEIMSSLN-HPHIIAIH 116
Query: 134 DFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRD 189
+ F++ I+MEY S GDLY+ I + + + QI+ AV Y H + HRD
Sbjct: 117 EVFENSSKIVIVMEYASRGDLYDYISERQ-QLSEREARHFFRQIVSAVHYCHQNRVVHRD 175
Query: 190 IKPENILIAGNWNIKLTDWGLATT--DKTSMERNVGSERYMAPELFESNLDREERTDAYD 247
+K ENIL+ N NIK+ D+GL+ ++ GS Y +PE+ Y
Sbjct: 176 LKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGK--------PYT 227
Query: 248 CAKVDIWAIGIVMLNIVFHKNPF 270
+VD W++G+++ +V PF
Sbjct: 228 GPEVDSWSLGVLLYILVHGTMPF 250
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 86.7 bits (213), Expect = 1e-16
Identities = 70/278 (25%), Positives = 127/278 (45%), Gaps = 24/278 (8%)
Query: 52 SEDDKGNDTKDGVMV---IGDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNN 108
+E D GN K + IG V ++E K + + K + +++
Sbjct: 6 TESDAGNTEKQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKY---K 62
Query: 109 VCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTK 164
+ + E++IQT + +H NI L+ +F ++I+EY GG+LY +K + + +
Sbjct: 63 IHHQLRREMEIQTSL-RHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQ 121
Query: 165 NVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNVGS 224
T I + + A+ Y H + + HRDIKPEN+L+ +K+ D+G + + G+
Sbjct: 122 AATYIAS-LSQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQSSNKRKTMCGT 180
Query: 225 ERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFA 284
Y+APE+ E N D + VD W +GI+ ++ PF +Q D
Sbjct: 181 LDYLAPEMVE-NRDHD--------YAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILK 231
Query: 285 ANREALFDVFSTMSYDFFQVLRHALTIDPTNR-NLEKV 321
+ F + +S + ++ L DP+ R ++EK+
Sbjct: 232 I--DLSFPLTPNVSEEAKNLISQLLVKDPSKRLSIEKI 267
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 86.7 bits (213), Expect = 1e-16
Identities = 65/212 (30%), Positives = 98/212 (45%), Gaps = 23/212 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I + HKN+ + YD F+ YI ME C GG+L + I + +I
Sbjct: 201 EVKILQALSGHKNLVQFYDAFEDNANVYIAMELCEGGELLDRILARGGKYSENDAKPVII 260
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDKTSMERN--VGSER 226
QIL+ V + H +G+ HRD+KPEN L N +K D+GL+ + N VGS
Sbjct: 261 QILNVVAFCHFQGVVHRDLKPENFLYTSKEENSQLKAIDFGLSDFVRPDERLNDIVGSAY 320
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ L R T+A D+W+IG++ ++ PF +T+
Sbjct: 321 YVAPEV----LHRSYTTEA------DVWSIGVIAYILLCGSRPFWA--RTESGIFRAVLK 368
Query: 287 REALFD--VFSTMSYDFFQVLRHALTIDPTNR 316
+ FD + +S D ++ L DP R
Sbjct: 369 ADPSFDEPPWPFLSSDAKDFVKRLLFKDPRRR 400
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 86.3 bits (212), Expect = 2e-16
Identities = 85/321 (26%), Positives = 142/321 (43%), Gaps = 78/321 (24%)
Query: 8 YKEGGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVI 67
+K+ +RD Y + + G++ V LA D + +KLVA+K I K + + K+G M
Sbjct: 10 WKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK----EALEGKEGSME- 64
Query: 68 GDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHK 127
E+ + KI KH
Sbjct: 65 -----------------------------------------------NEIAVLHKI-KHP 76
Query: 128 NITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSR 183
NI L D ++S Y+IM+ SGG+L++ I + + ++ + +I Q+LDAV+Y+H
Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTE-RDASRLIFQVLDAVKYLHDL 135
Query: 184 GIYHRDIKPENIL---IAGNWNIKLTDWGLATTDK--TSMERNVGSERYMAPELFESNLD 238
GI HRD+KPEN+L + + I ++D+GL+ + + + G+ Y+APE+ L
Sbjct: 136 GIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEV----LA 191
Query: 239 REERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANRE---ALFDVFS 295
++ + A DC W+IG++ ++ PF N A E +D S
Sbjct: 192 QKPYSKAVDC-----WSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDIS 246
Query: 296 TMSYDFFQVLRHALTIDPTNR 316
+ DF +RH + DP R
Sbjct: 247 DSAKDF---IRHLMEKDPEKR 264
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 86.3 bits (212), Expect = 2e-16
Identities = 83/315 (26%), Positives = 153/315 (48%), Gaps = 61/315 (19%)
Query: 23 DISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNTVNSS 82
+ +EG ++ + + ++++ Y F KG+ G+++ +K+ ET +
Sbjct: 95 NFTEGKVPHIRIENGAAIEEI----YTFGRILGKGSF---GIVIEATDKETETKWAI--- 144
Query: 83 QEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS---- 138
+++ K + + K+L R EV+I + KH++I L F++
Sbjct: 145 ----KKVNKEKAGSSAVKLLER-----------EVNILKSV-KHEHIIHLEQVFETPKKM 188
Query: 139 YIIMEYCSGGDLYEAIKDDMVPRKTKNVTN-IINQILDAVEYVHSRGIYHRDIKPENILI 197
Y++ME C G+L E + D ++N T II + A+ Y+H+ I HRD+K ENI++
Sbjct: 189 YLVMELCEDGELKEIL--DRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMV 246
Query: 198 AG---------NWNIKLTDWGLA----TTDKTSMERNVGSERYMAPELFESNLDREERTD 244
N NIK+TD+GLA + + ++ G+ YMAPE+
Sbjct: 247 KSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVI----------S 296
Query: 245 AYDCA-KVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD--VFSTMSYDF 301
A+D + + DIW+IG+VM ++ + PF +A+ +K F E F+ V++++S
Sbjct: 297 AHDYSQQCDIWSIGVVMYMLLRGEPPF-LASSEEKLF-ELIRKGELHFENAVWNSISDCA 354
Query: 302 FQVLRHALTIDPTNR 316
VL+ + +DP +R
Sbjct: 355 KSVLKQLMKVDPAHR 369
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 86.3 bits (212), Expect = 2e-16
Identities = 73/271 (26%), Positives = 120/271 (43%), Gaps = 63/271 (23%)
Query: 10 EGGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGD 69
E G+ +Y+L + EG++G V A DT AVK I KS I D
Sbjct: 12 EKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSR-------------IAD 58
Query: 70 EKDDETNNTVNSSQE-KKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKN 128
N ++ +E + ++LKH + +VL+ +TKI
Sbjct: 59 -----LNFSLQIKREIRTLKMLKHPHIVRLHEVLAS---------------KTKIN---- 94
Query: 129 ITELYDFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHR 188
++ME +GG+L++ I + +T + Q++D + Y HS+G++HR
Sbjct: 95 -----------MVMELVTGGELFDRIVSNGKLTETDG-RKMFQQLIDGISYCHSKGVFHR 142
Query: 189 DIKPENILIAGNWNIKLTDWGLAT-----TDKTSMERNVGSERYMAPELFESNLDREERT 243
D+K EN+L+ +IK+TD+GL+ D + GS Y+APE+ +
Sbjct: 143 DLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANR------- 195
Query: 244 DAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
YD A DIW+ G+++ I+ PF N
Sbjct: 196 -GYDGAASDIWSCGVILYVILTGCLPFDDRN 225
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 86.3 bits (212), Expect = 2e-16
Identities = 51/165 (30%), Positives = 86/165 (51%), Gaps = 16/165 (9%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I + + H NI +Y+ F++ ++ME+ +GG+LY+ + + V + + I
Sbjct: 130 EVQIMSSV-HHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTE-EEARRIFR 187
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATT--DKTSMERNVGSERYMA 229
Q+ AV Y H I HRD+K ENIL+ N K+ D+GL+ D+ + GS Y +
Sbjct: 188 QVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYAS 247
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
PE+ E Y +VD W++G+++ +V+ PF +N
Sbjct: 248 PEIVEGT--------PYQGPEVDCWSLGVLLYTLVYGSMPFDGSN 284
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 85.9 bits (211), Expect = 2e-16
Identities = 61/203 (30%), Positives = 107/203 (52%), Gaps = 21/203 (10%)
Query: 122 KIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K KH NI D + D ++IMEY GG L + + ++ + + + L +
Sbjct: 670 KGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEG--QIGAVCRETLSGL 727
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGL-ATTDKTSMERN--VGSERYMAPELFE 234
E++HS+G+ HRDIK +NIL++ +IKLTD+G A ++ +++R VG+ +MAPE+
Sbjct: 728 EFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEV-- 785
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTD-KAFCYFAANREALFDV 293
+ R+E KVDIW++GI+++ ++ + P+ N+T +A A N
Sbjct: 786 --VSRKEYG-----PKVDIWSLGIMIIEMIEGEPPY--LNETPLRALYLIATNGTPKLKE 836
Query: 294 FSTMSYDFFQVLRHALTIDPTNR 316
+S + L L ++P +R
Sbjct: 837 PENLSSSLKKFLDWCLCVEPEDR 859
>SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 652
Score = 85.9 bits (211), Expect = 2e-16
Identities = 67/272 (24%), Positives = 120/272 (43%), Gaps = 62/272 (22%)
Query: 16 DRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDET 75
+ Y++I+++ G +G V L DT ++L+A+K I K+E + +
Sbjct: 133 NHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTE-----------------RRPKL 175
Query: 76 NNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF 135
SSQ++K R E+ I K H N+ L +
Sbjct: 176 GRANASSQKEKVRR--------------------------EIAILKKC-VHPNVVRLREV 208
Query: 136 FDS------YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRD 189
D Y+++EY SGG++ D V ++ +EY+H +GI HRD
Sbjct: 209 IDDPSSTKVYLVLEYMSGGEVPWTDCDSPV-LSISEARQYFRDVVLGLEYLHYQGIIHRD 267
Query: 190 IKPENILIAGNWNIKLTDW--------GLATTDKTSMERNVGSERYMAPELFESNLDREE 241
IKP N+L+ + +K++D+ GL + + + VG+ + APEL ++LDR
Sbjct: 268 IKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPR 327
Query: 242 RTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVA 273
+ +D+WA+G+ + ++F + PF +
Sbjct: 328 PKIS---EAIDVWALGVTLFCLLFGRCPFNAS 356
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 85.9 bits (211), Expect = 2e-16
Identities = 52/154 (33%), Positives = 84/154 (53%), Gaps = 19/154 (12%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAI-KDDMVPRKTKNVTNIINQILDAVEYV 180
H NIT LY+ + Y+ MEYC G+LY+ + ++ + KT I+ Q+ A++Y+
Sbjct: 82 HPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKT--TCRIMWQLCCAIQYL 139
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLA----TTDKTSMERNVGSERYMAPELFESN 236
H +G HRD+K ENI + +N+KL D+G + + +T M G+ Y APEL + +
Sbjct: 140 HRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTFMNTRCGTVAYCAPELVQGH 199
Query: 237 LDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
Y VDIW++GI+M ++ + PF
Sbjct: 200 --------KYIGECVDIWSLGIIMYALLIGRLPF 225
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 85.9 bits (211), Expect = 2e-16
Identities = 50/163 (30%), Positives = 81/163 (49%), Gaps = 15/163 (9%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ +H NI LY+ D+ Y+I+E GGD+++ I QI+ A+
Sbjct: 68 KLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN-IKLTDWGLATTDKTS--MERNVGSERYMAPELFE 234
Y H + HRD+KPEN++ +KLTD+G + + + + GS Y APE+
Sbjct: 128 SYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILL 187
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTD 277
D YD VDIW++G+++ +V + PF AN ++
Sbjct: 188 G--------DEYDAPAVDIWSLGVILFMLVCEQPPFQEANDSE 222
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 85.9 bits (211), Expect = 2e-16
Identities = 88/355 (24%), Positives = 158/355 (43%), Gaps = 68/355 (19%)
Query: 4 DYEVYKEGGLLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDG 63
D VY + LRD Y + + + G+ G V LA + + K VA+K I K +
Sbjct: 208 DQSVYPKA--LRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRK---------- 255
Query: 64 VMVIGDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKI 123
IG ++ + V + E++I K+
Sbjct: 256 -FAIGSAREADPALNVET----------------------------------EIEILKKL 280
Query: 124 GKHKNITELYDFFDS---YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN--QILDAVE 178
H I ++ +FFD+ YI++E GG+L++ + + ++ K T + Q+L AV+
Sbjct: 281 N-HPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGN---KRLKEATCKLYFYQMLLAVQ 336
Query: 179 YVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA-TTDKTSMERNV-GSERYMAPELF 233
Y+H GI HRD+KPEN+L++ IK+TD+G + +TS+ R + G+ Y+APE+
Sbjct: 337 YLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVL 396
Query: 234 ESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTV-ANQTDKAFCYFAANREALFD 292
S T Y+ A VD W++G+++ + PF+ Q + + +
Sbjct: 397 VS-----VGTAGYNRA-VDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPE 450
Query: 293 VFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSLDSDEES 347
V++ +S +++ L +DP R + L + M ++ + L + ES
Sbjct: 451 VWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENES 505
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 85.9 bits (211), Expect = 2e-16
Identities = 61/197 (30%), Positives = 96/197 (47%), Gaps = 23/197 (11%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALYEV-DIQTKIG-----KHKNITELYDFFD----SYI 140
K +S+++ K L+ + C A+ + DIQ ++ H NI +YD SY+
Sbjct: 189 KSDRSVVAIKQLNTQFSTRCSRAIAKTRDIQNEVEVMKKLSHPNIVAIYDCITVAKYSYM 248
Query: 141 IMEYCSGGDLYEAIKDDMVPRKTKNVT---NIINQILDAVEYVHSRGIYHRDIKPENILI 197
++EY GG+ + + D + + Q++DAV Y+HS GI HRDIKPENIL
Sbjct: 249 VIEYVGGGEFFSKLVDSKYNQMGLGESLGKYFAFQLIDAVLYLHSVGICHRDIKPENILC 308
Query: 198 AGNWN---IKLTDWGLATTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIW 254
+ +KLTD+G+A M+ + G+ Y APE+ + KVDIW
Sbjct: 309 SNKAERCILKLTDFGMAKNSVNRMKTHCGTPSYCAPEIVANQ-------GVEYTPKVDIW 361
Query: 255 AIGIVMLNIVFHKNPFT 271
++G V+ PF+
Sbjct: 362 SLGCVLFITFSGYPPFS 378
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 85.9 bits (211), Expect = 2e-16
Identities = 62/199 (31%), Positives = 97/199 (48%), Gaps = 20/199 (10%)
Query: 82 SQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALY-EVDIQTKIGKHKNITELYDFFDS-- 138
S + K+ LK Q+ + S+ + + E + EV + + HKN+ + YD F+
Sbjct: 139 SAKGKKGSLKGQEVAVKVIPKSKMTTAIAIEDVSREVKMLRALTGHKNLVQFYDAFEDDE 198
Query: 139 --YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
YI+ME C GG+L + I + ++ QIL V Y H +G+ HRD+KPEN L
Sbjct: 199 NVYIVMELCKGGELLDKILQRGGKYSEDDAKKVMVQILSVVAYCHLQGVVHRDLKPENFL 258
Query: 197 IAGNWN---IKLTDWGLATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKV 251
+ +K D+GL+ K N VGS Y+APE+ L R T+A
Sbjct: 259 FSTKDETSPLKAIDFGLSDYVKPDERLNDIVGSAYYVAPEV----LHRTYGTEA------ 308
Query: 252 DIWAIGIVMLNIVFHKNPF 270
D+W+IG++ ++ PF
Sbjct: 309 DMWSIGVIAYILLCGSRPF 327
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 85.5 bits (210), Expect = 3e-16
Identities = 56/177 (31%), Positives = 83/177 (46%), Gaps = 38/177 (21%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIK-----DDMVPRKTKNVTNIINQ 172
K+ ++ L+ F Y ++EY GD +K D+ R Q
Sbjct: 233 KLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARY------YAAQ 286
Query: 173 ILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA-----TTD---------KTSM 218
I+DA++Y+HS GI HRDIKPENIL+ G IKLTD+G A T + T
Sbjct: 287 IIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRS 346
Query: 219 ERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQ 275
+ VG+ Y++PEL D++ + DIWA G ++ ++ K PF N+
Sbjct: 347 KSFVGTAEYVSPELL---------NDSFTDYRCDIWAFGCILFQMIAGKPPFKATNE 394
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 85.5 bits (210), Expect = 3e-16
Identities = 65/215 (30%), Positives = 112/215 (51%), Gaps = 23/215 (10%)
Query: 63 GVMVIGDEKDDETNNTVNSSQEKKQRLLKHQKSLI-SDKVLSRFSNNVCFEALYEVDIQT 121
G+ IG V ++EKK + K+L S+ V S+ V E++IQ+
Sbjct: 116 GMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQV----RREIEIQS 171
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTN-IINQILDA 176
+ +HKNI LY F Y+I+E+ G+LY+ ++ R ++ V + I Q+ +A
Sbjct: 172 NL-RHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLR--RAKRFSEEVASKYIFQMANA 228
Query: 177 VEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-GSERYMAPELFES 235
+ Y+H + + HRDIKPENIL+ + IKL+D+G + ++ + G+ Y+ PE+ E
Sbjct: 229 LSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEG 288
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
+E T+ KVD+W++G++ + PF
Sbjct: 289 ----KEHTE-----KVDLWSLGVLTYEFLVGAPPF 314
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 85.5 bits (210), Expect = 3e-16
Identities = 58/200 (29%), Positives = 104/200 (52%), Gaps = 23/200 (11%)
Query: 126 HKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
HKNI D F + +++MEY GG L E + ++ + + I + L+ ++++H
Sbjct: 440 HKNIVNFIDTFFYKSELWMVMEYMRGGSLTEVVTNNTLSEG--QIAAICKETLEGLQHLH 497
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN---VGSERYMAPELFESNLD 238
GI HRDIK +NIL++ +IKLTD+G ++M + VG+ +MAPE+ +
Sbjct: 498 ENGIVHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEV----VT 553
Query: 239 REERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALF--DVFST 296
R+E KVD+W++GI+ + +V + P+ N + + ++ S+
Sbjct: 554 RKEYG-----FKVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPELLSS 608
Query: 297 MSYDFFQVLRHALTIDPTNR 316
+ +DF L +LT++P R
Sbjct: 609 VFHDF---LSKSLTVNPKQR 625
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 85.5 bits (210), Expect = 3e-16
Identities = 55/165 (33%), Positives = 92/165 (55%), Gaps = 25/165 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAI--KDDMVPRKTKNVTNIINQILDAVE 178
+H NI +L + F++ Y++ME +GG+L++ I K R + T ++ +LD V
Sbjct: 151 RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTER---DATRVLQMVLDGVR 207
Query: 179 YVHSRGIYHRDIKPENILI---AGNWNIKLTDWGLATT----DKTSMERNVGSERYMAPE 231
Y+H+ GI HRD+KPEN+L + I +TD+GLA+ D M+ G+ Y+APE
Sbjct: 208 YLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPE 267
Query: 232 LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQT 276
+ L R+ T++ VD+WA+G++ ++ PF N+T
Sbjct: 268 V----LVRKPYTNS-----VDMWALGVIAYILLSGTMPFEDDNRT 303
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 85.5 bits (210), Expect = 3e-16
Identities = 82/319 (25%), Positives = 141/319 (43%), Gaps = 47/319 (14%)
Query: 15 RDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSED--DKGNDTKDGVMV--IGDE 70
++ + I D+S+G +G V KK+ + + K GN + V IG
Sbjct: 246 KEEEEKIPDLSKGQFG-VQARGQKAKKKMTDAEVLTKLRTIVSIGNPDRKYRKVDKIGSG 304
Query: 71 KDDETNNTVNSSQEK----KQRLLKHQ--KSLISDKVLSRFSNNVCFEALYEVDIQTKIG 124
+ S E KQ LK Q K LI +++L N
Sbjct: 305 ASGSVYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMREN----------------- 347
Query: 125 KHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
KH NI D + + +++MEY +GG L + + + + + + + ++L A+E++
Sbjct: 348 KHANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTECQM--EDGIIAAVCREVLQALEFL 405
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGSERYMAPELFESNL 237
HSR + HRDIK +NIL+ + ++KLTD+G + ++ VG+ +MAPE+
Sbjct: 406 HSRHVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQRKRTTMVGTPYWMAPEVV---- 461
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
T KVD+W++GI+ + +V + P+ N +A A N + F +M
Sbjct: 462 -----TRKQYGPKVDVWSLGIMAIEMVEGEPPYLNENPL-RAIYLIATNGKPDFPGRDSM 515
Query: 298 SYDFFQVLRHALTIDPTNR 316
+ F + AL + NR
Sbjct: 516 TLLFKDFVDSALEVQVENR 534
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/202 (29%), Positives = 105/202 (51%), Gaps = 20/202 (9%)
Query: 86 KQRLLKHQ--KSLISDKVLSRFSNNVCFEALYEVDIQT-KIGKHKNITELYDFFDS---- 138
K +L HQ K ++ K++ + + + L +IQ + H NI +L++ ++
Sbjct: 62 KVKLGVHQLTKEKVAVKIMDKAKMDAKAQKLLSREIQAMEEMNHPNIVKLFEVVETLTRV 121
Query: 139 YIIMEYCSGGDLYEAIKDDMVPRKTK-NVTNIINQILDAVEYVHSRGIYHRDIKPENILI 197
++++EY SGG+LY + + + T+ + + QI+ AV ++HSR I HRDIK EN++
Sbjct: 122 HLVIEYASGGELYTYVHER--GKLTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMF 179
Query: 198 AGNWNIKLTDWGLA-TTDKTSMERN-VGSERYMAPELFESNLDREERTDAYDCAKVDIWA 255
+ +KL D+G + D+ M R GS Y APELF+ +Y VD+WA
Sbjct: 180 SSPNTVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDT--------SYAGELVDVWA 231
Query: 256 IGIVMLNIVFHKNPFTVANQTD 277
+G+++ ++ PF D
Sbjct: 232 LGVLLFFMLIGVTPFKAETVPD 253
>At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 366
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 17/208 (8%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E++I + H N+ + ++ FD +++E+ G L A K + + ++
Sbjct: 125 EIEILRDVN-HPNVVKCHEMFDQNGEIQVLLEFMDKGSLEGAHV-----WKEQQLADLSR 178
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSME---RNVGSERYM 228
QIL + Y+HSR I HRDIKP N+LI N+K+ D+G++ +M+ +VG+ YM
Sbjct: 179 QILSGLAYLHSRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPCNSSVGTIAYM 238
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANRE 288
+PE ++L++ + YD DIW++G+ +L + PF V+ Q D A A
Sbjct: 239 SPERINTDLNQGK----YDGYAGDIWSLGVSILEFYLGRFPFPVSRQGDWASLMCAICMS 294
Query: 289 ALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ +T S +F + L +P R
Sbjct: 295 QPPEAPATASPEFRHFISCCLQREPGKR 322
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 85.1 bits (209), Expect = 4e-16
Identities = 64/258 (24%), Positives = 116/258 (44%), Gaps = 66/258 (25%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
+++ + +G +G V LA + Q K ++A+K +FK++ +K
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG------------------- 173
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
++HQ L R EV+IQ+ + +H NI LY +F
Sbjct: 174 ------------VEHQ--------LRR-----------EVEIQSHL-RHPNILRLYGYFH 201
Query: 138 S----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPE 193
Y+I+EY G +Y ++ + + I ++ +A+ Y HS+ + HRDIKPE
Sbjct: 202 DATRVYLILEYAPLGTVYRELQK-LSKFDEQRTATYITELANALSYCHSKRVIHRDIKPE 260
Query: 194 NILIAGNWNIKLTDWGLATTDKTSMERNV-GSERYMAPELFESNLDREERTDAYDCAKVD 252
N+L+ +K+ D+G + +S + G+ Y+ PE+ E + E KVD
Sbjct: 261 NLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDE---------KVD 311
Query: 253 IWAIGIVMLNIVFHKNPF 270
+W++G++ + K PF
Sbjct: 312 LWSLGVLCYEFLVGKPPF 329
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 84.7 bits (208), Expect = 5e-16
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 24/213 (11%)
Query: 114 LYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNI 169
L E+ I + H NI + D F+ YI++E C G L E +K V + + V
Sbjct: 127 LSEIQIHKSMS-HPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPE-VRFF 184
Query: 170 INQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN---VGSER 226
QI A++Y+HSR + HRD+K NI N+N+K+ D+GLA ER G+
Sbjct: 185 TTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPN 244
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQT---DKAFCYF 283
Y+APE+ + +VDIW++G+++ ++ K PF + ++ C
Sbjct: 245 YIAPEVLMGK-------HSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKC-- 295
Query: 284 AANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
R+ F +S + ++R L++DP R
Sbjct: 296 ---RDFSFPRDKPISDEGKILIRDILSLDPIER 325
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 84.7 bits (208), Expect = 5e-16
Identities = 63/229 (27%), Positives = 107/229 (46%), Gaps = 41/229 (17%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAI------KDDMVPRKTKN------ 165
KI H NI +L++ ++ Y+IMEY SGG++++ + K+ K +
Sbjct: 108 KILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQ 167
Query: 166 ----------VTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--T 213
++ + I+ AV+Y H + I HRD+K EN+L+ + NIK+ D+G + T
Sbjct: 168 TIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT 227
Query: 214 DKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVA 273
++ GS Y APELF+ YD +VD+W++G+++ +V PF
Sbjct: 228 VGGKLDTFCGSPPYAAPELFQGK--------KYDGPEVDVWSLGVILYTLVSGSLPFDGQ 279
Query: 274 NQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR-NLEKV 321
N + F MS D +L+ L ++P R LE++
Sbjct: 280 NLKELRERVLRGKYRIPF----YMSTDCENLLKRFLVLNPIKRGTLEQI 324
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 84.7 bits (208), Expect = 5e-16
Identities = 64/213 (30%), Positives = 97/213 (45%), Gaps = 26/213 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPR---KTKNVTN 168
EV+I + +H NI L D F+ +I+ME C GG+L++ I V R +
Sbjct: 105 EVEIMKHMPRHPNIVSLKDAFEDDDAVHIVMELCEGGELFDRI----VARGHYTERAAAA 160
Query: 169 IINQILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATTDKTSMERN--VG 223
++ IL+ V+ H G+ HRD+KPEN L A +K D+GL+ K N VG
Sbjct: 161 VMKTILEVVQICHKHGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEGFNEIVG 220
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYF 283
S YMAPE+ N E VDIW+ G+++ ++ PF + A
Sbjct: 221 SPYYMAPEVLRRNYGPE----------VDIWSAGVILYILLCGVPPFWAETEQGVAQAII 270
Query: 284 AANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ + D + +S ++R L DP R
Sbjct: 271 RSVIDFKRDPWPRVSETAKDLVRKMLEPDPKKR 303
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 84.7 bits (208), Expect = 5e-16
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 20/205 (9%)
Query: 82 SQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALY-EVDIQTKIGKHKNITELYDFFDS-- 138
S + K+ LK Q + S+ + + E + EV I + HKN+ + YD F+
Sbjct: 140 SAKGKKGSLKGQDVAVKVIPKSKMTTAIAIEDVRREVKILRALTGHKNLVQFYDAFEDDE 199
Query: 139 --YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
YI+ME C GG+L + I + ++ QIL V Y H +G+ HRD+KPEN L
Sbjct: 200 NVYIVMELCQGGELLDKILQRGGKYSEVDAKKVMIQILSVVAYCHLQGVVHRDLKPENFL 259
Query: 197 IA---GNWNIKLTDWGLATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKV 251
+ +K D+GL+ + N VGS Y+APE+ L R T+A
Sbjct: 260 FTTKDESSPLKAIDFGLSDYVRPDERLNDIVGSAYYVAPEV----LHRTYGTEA------ 309
Query: 252 DIWAIGIVMLNIVFHKNPFTVANQT 276
D+W+IG++ ++ PF +++
Sbjct: 310 DMWSIGVIAYILLCGSRPFWARSES 334
>At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 348
Score = 84.7 bits (208), Expect = 5e-16
Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 17/208 (8%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E++I + H N+ + +D FD +++E+ G L A + + + ++
Sbjct: 116 EIEILRSVD-HPNVVKCHDMFDHNGEIQVLLEFMDQGSLEGAHI-----WQEQELADLSR 169
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSME---RNVGSERYM 228
QIL + Y+H R I HRDIKP N+LI N+K+ D+G++ +M+ +VG+ YM
Sbjct: 170 QILSGLAYLHRRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPCNSSVGTIAYM 229
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANRE 288
+PE ++L+ YD D+W++G+ +L + PF V+ Q D A A
Sbjct: 230 SPERINTDLNH----GRYDGYAGDVWSLGVSILEFYLGRFPFAVSRQGDWASLMCAICMS 285
Query: 289 ALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ +T S +F + L DP R
Sbjct: 286 QPPEAPATASQEFRHFVSCCLQSDPPKR 313
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 84.3 bits (207), Expect = 7e-16
Identities = 74/307 (24%), Positives = 133/307 (43%), Gaps = 38/307 (12%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
+KL + + +GS G V LA + + +L A+K + K + N
Sbjct: 81 WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFV---------------HCSNNG 125
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
TV +S I+ + S S + E+ I K+ H N+ L++ ++
Sbjct: 126 TVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIM-KLISHTNVMALFEVWE 184
Query: 138 S----YIIMEYCSGGDLYE-AIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKP 192
+ Y+++EY GG+L++ + +P + + QI++ V Y HS I HRD+KP
Sbjct: 185 NKSELYLVLEYVDGGELFDYLVSKGKLPER--EAIHYFKQIVEGVSYCHSFNICHRDLKP 242
Query: 193 ENILI-AGNWNIKLTDWGLATTDKTS--MERNVGSERYMAPELFESNLDREERTDAYDCA 249
EN+L+ N IK+ D+G+A + + ++ + GS Y +PE+ Y
Sbjct: 243 ENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGR--------PYHGG 294
Query: 250 KVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHAL 309
D+W+ GIV+ ++ PF D + + + S +S + ++ L
Sbjct: 295 PSDVWSCGIVLFALLTGHLPF----NDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKIL 350
Query: 310 TIDPTNR 316
IDP R
Sbjct: 351 VIDPEKR 357
>YJL165c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 855
Score = 84.3 bits (207), Expect = 7e-16
Identities = 60/209 (28%), Positives = 102/209 (48%), Gaps = 43/209 (20%)
Query: 129 ITELYDFFDSYI-IMEYCSGGDLYEAIKDDMVPRKTKNVTN------------------- 168
I +L ++ +S++ +ME+C+ GDLY + + + ++ N ++
Sbjct: 606 ILDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEA 665
Query: 169 --IINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV---- 222
+ Q+L+ V+Y+H GI H D+KPENIL N +K+ D+G ++ +T+ E++V
Sbjct: 666 DCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQS 725
Query: 223 ---GSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVA-NQTDK 278
GSE Y+APE F R YD VD W+ GIV +V + + +A + D
Sbjct: 726 GAMGSEPYVAPEEF-------IRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDS 778
Query: 279 AFCYFAANREALFDVFSTMSYDFFQVLRH 307
F F L ++ + F+ LRH
Sbjct: 779 LFKSF------LSEIKDDGQFYLFEELRH 801
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 84.3 bits (207), Expect = 7e-16
Identities = 66/213 (30%), Positives = 108/213 (49%), Gaps = 26/213 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ + KI KH+NI L D ++S Y++M+ SGG+L++ I + + K+ + +I
Sbjct: 69 EIAVLRKI-KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTE-KDASTLIR 126
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDKTS--MERNVGSER 226
Q+LDAV Y+H GI HRD+KPEN+L I ++D+GL+ + M G+
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ L ++ + A DC W+IG++ ++ PF N + A
Sbjct: 187 YVAPEV----LAQKPYSKAVDC-----WSIGVIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 287 RE---ALFDVFSTMSYDFFQVLRHALTIDPTNR 316
E +D S + DF +R+ + DP R
Sbjct: 238 YEFDSPYWDDISDSAKDF---IRNLMEKDPNKR 267
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 84.3 bits (207), Expect = 7e-16
Identities = 59/181 (32%), Positives = 92/181 (50%), Gaps = 26/181 (14%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
+H+NI LYD + +++MEYC+GGDL + ++ + + ++QI A+ +
Sbjct: 64 QHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSED-TIRVFLHQIAAAMRIL 122
Query: 181 HSRGIYHRDIKPENILIA---------GNWNIKLTDWGLATTDKTSMERNV--GSERYMA 229
HS+GI HRD+KP+NIL++ IK+ D+G A ++M GS YMA
Sbjct: 123 HSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMA 182
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREA 289
PE+ S YD AK D+W+IG V+ + K PF AN ++ NR
Sbjct: 183 PEVIMS--------QHYD-AKADLWSIGTVIYQCLVGKPPFQ-ANSPQDLRMFYEKNRSL 232
Query: 290 L 290
+
Sbjct: 233 M 233
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 84.3 bits (207), Expect = 7e-16
Identities = 51/167 (30%), Positives = 85/167 (50%), Gaps = 22/167 (13%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYE---AIKDDMVPRKTKNVTN 168
E+ I ++ NI E + ++ +I+MEYC GG+LY+ A+ D K
Sbjct: 76 EIRIMKQLSGEPNIVEFKNAYEDKDSVHIVMEYCGGGELYDKILALYDVGKSYSEKEAAG 135
Query: 169 IINQILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLAT--TDKTSMERNVG 223
II I++ V+ H G+ HRD+KPEN L+ N +K+ D+G + + + G
Sbjct: 136 IIRSIVNVVKNCHYMGVMHRDLKPENFLLTSNDDNATVKVIDFGCSVFIEEGKVYQDLAG 195
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
S+ Y+APE+ + N +E DIW+ GI++ ++ K+PF
Sbjct: 196 SDYYIAPEVLQGNYGKE----------ADIWSAGIILYILLCGKSPF 232
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 84.3 bits (207), Expect = 7e-16
Identities = 67/257 (26%), Positives = 117/257 (45%), Gaps = 54/257 (21%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
++LIE + G+YG V T+ +L A+K VM + +++++E
Sbjct: 32 FELIEVVGNGTYGQVYKGRHTKTGQLAAIK----------------VMDVTEDEEEEIKL 75
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQ-TKIGKHKNITELYDFF 136
+N VL ++SN+ Y I+ + GK +
Sbjct: 76 EIN--------------------VLKKYSNHRNIATYYGAFIKKSPPGKDDQL------- 108
Query: 137 DSYIIMEYCSGGDLYEAIKDDMVPR-KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENI 195
+++MEYC G + + +K K + + I +IL + Y+HS + HRDIK +N+
Sbjct: 109 --WLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNV 166
Query: 196 LIAGNWNIKLTDWGL-ATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKVD 252
L+ N +KL D+G+ A D+T RN +G+ +MAPE+ +E DA + D
Sbjct: 167 LLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIAC----DENPDATYDNRSD 222
Query: 253 IWAIGIVMLNIVFHKNP 269
+W++GI L + + P
Sbjct: 223 LWSLGITALEMAESQPP 239
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 84.0 bits (206), Expect = 9e-16
Identities = 66/251 (26%), Positives = 121/251 (47%), Gaps = 30/251 (11%)
Query: 23 DISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKD--DETNNTVN 80
D+S+ ++ Y + + K + YI S +G + G + +G K+ + +N+T +
Sbjct: 17 DLSD-TFQYPQRTDEQRRKHVTFGPYILGSTLGEG---EFGKVKLGWPKNFSNSSNSTFD 72
Query: 81 SSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDSY- 139
++ +L+K D + + + V +Y K H NI +L + +
Sbjct: 73 FPKQVAIKLIKR------DSISNDYRKEV---KIYREINALKHLSHPNIVKLEEVLQNSR 123
Query: 140 ---IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
I++EY GG+ Y+ I+ K N + +Q++ V Y+HS+G+ HRD+K EN+L
Sbjct: 124 YIGIVLEYACGGEFYKYIQKKR-RLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLL 182
Query: 197 IAGNWNIKLTDWGLAT---TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDI 253
+ N N+ +TD+G + M+ + GS Y APEL S + Y+ K DI
Sbjct: 183 LDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVIS-------AEPYEARKADI 235
Query: 254 WAIGIVMLNIV 264
W+ G+++ I+
Sbjct: 236 WSCGVILYAIL 246
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 84.0 bits (206), Expect = 9e-16
Identities = 70/259 (27%), Positives = 114/259 (43%), Gaps = 67/259 (25%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
Y++ +I G++ V L + K+ VA+K + K++ D
Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLD---------------------- 111
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
+K QRLL + S + E L+ H NI LY+ +
Sbjct: 112 ------QKTQRLLSREISSM--------------EKLH----------HPNIIRLYEVVE 141
Query: 138 S----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPE 193
+ +++MEY GG+L+ I + + ++ I +QI+ AV+++H I HRD+K E
Sbjct: 142 TLSKLHLVMEYAGGGELFGKISTEGKLSEPESKL-IFSQIVSAVKHMHENQIIHRDLKAE 200
Query: 194 NILIAGNWNIKLTDWGLATTDKTSMERNV--GSERYMAPELFESNLDREERTDAYDCAKV 251
N+ N +K+ D+G +T K N GS Y APELF R + Y V
Sbjct: 201 NVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELF--------RDEHYIGIYV 252
Query: 252 DIWAIGIVMLNIVFHKNPF 270
DIWA+G+++ +V PF
Sbjct: 253 DIWALGVLLYFMVTGTMPF 271
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 84.0 bits (206), Expect = 9e-16
Identities = 58/180 (32%), Positives = 89/180 (49%), Gaps = 27/180 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
KH+N+ L ++ Y++ME+C+GGDL + ++ + + + + QI A+E +
Sbjct: 67 KHENLVGLLKCTETPTHVYLVMEFCNGGDLADYLQQKTTLNED-TIQHFVVQIAHALEAI 125
Query: 181 HSRGIYHRDIKPENILIAGNWN----------IKLTDWGLA--TTDKTSMERNVGSERYM 228
+ +GI HRD+KP+NIL+ N IKL D+G A D GS YM
Sbjct: 126 NKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFLNDGVMAATLCGSPMYM 185
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANRE 288
APE+ S YD AK D+W+IG ++ + K PF VA + Y+ RE
Sbjct: 186 APEVIMSM--------QYD-AKADLWSIGTILFQCLTGKAPF-VAQTPPQLKAYYEKTRE 235
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 84.0 bits (206), Expect = 9e-16
Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 19/155 (12%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H NI L++ ++ Y++ E+ GG+LY I P + + ++ Q+L AV+++H
Sbjct: 102 HPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGG-PLREIHAAPLLKQLLLAVKHMH 160
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLATT------DKTSMERNVGSERYMAPELFES 235
S G HRDIK EN+L+ +KL D+G +T ++ GS Y APELF
Sbjct: 161 SLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGTGANQKLDTFCGSPPYAAPELFSD 220
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
D Y A VD+WA+GI++ +V PF
Sbjct: 221 --------DHYIGAPVDVWALGILLYFMVVGNMPF 247
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 83.6 bits (205), Expect = 1e-15
Identities = 68/279 (24%), Positives = 123/279 (43%), Gaps = 38/279 (13%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF----FDSYIIMEYCS 146
KH +++ K + ++ + + E+ + + H NI + + F ++ YI++EYC+
Sbjct: 45 KHTDQVVAIKEVVYENDEELNDIMAEISLLKNLN-HNNIVKYHGFIRKSYELYILLEYCA 103
Query: 147 GGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLT 206
G L I + Q L ++Y+H G+ HRDIK NIL++ + +KL
Sbjct: 104 NGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLA 163
Query: 207 DWGLATTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFH 266
D+G++T +S G+ +MAPE+ +R T + DIW++G ++ ++
Sbjct: 164 DFGVSTIVNSSALTLAGTLNWMAPEILG---NRGASTLS------DIWSLGATVVEMLTK 214
Query: 267 KNPFTVANQTDKAFCYFAANREALF--DVFSTMSYDFF---------------QVLRHAL 309
P+ N TD A Y+A + + FS DF Q+L+H
Sbjct: 215 NPPY--HNLTD-ANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVW 271
Query: 310 TIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSLDSDEESV 348
N ++K + + E D +Y+ D EE +
Sbjct: 272 INSTENVKVDK----LNKFKEDFTDADYHWDADFQEEKL 306
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 83.6 bits (205), Expect = 1e-15
Identities = 51/180 (28%), Positives = 92/180 (50%), Gaps = 12/180 (6%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF----DSYIIMEYCS 146
K L + KV+ S + + E+DI H NI +L D F + +I++E+C+
Sbjct: 54 KETSVLAAAKVIDTKSEEELEDYMVEIDILASCD-HPNIVKLLDAFYYENNLWILIEFCA 112
Query: 147 GGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLT 206
GG + + + P + + Q LDA+ Y+H I HRD+K NIL + +IKL
Sbjct: 113 GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLA 172
Query: 207 DWGLATTDKTSMERN---VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNI 263
D+G++ + +++R +G+ +MAPE+ ++ D K D+W++GI ++ +
Sbjct: 173 DFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYD----YKADVWSLGITLIEM 228
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 83.6 bits (205), Expect = 1e-15
Identities = 52/163 (31%), Positives = 92/163 (55%), Gaps = 19/163 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ + K+ +H NI +L+D +D Y++ME +GG+L++ I + ++ +N+I
Sbjct: 69 EIKVLRKL-RHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTE-QDASNLIR 126
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLA-TTDKTSMERNVGSERY 227
Q+L+AV ++H G+ HRD+KPEN+L + I ++D+GL+ T D M G+ Y
Sbjct: 127 QVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSGVMATACGTPGY 186
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
+APE+ + Y A VD+W+IG++ ++ PF
Sbjct: 187 VAPEVLQQK--------PYGKA-VDVWSIGVIAYILLCGYPPF 220
>CE17343 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 83.6 bits (205), Expect = 1e-15
Identities = 53/155 (34%), Positives = 82/155 (52%), Gaps = 15/155 (9%)
Query: 122 KIGKHKNITELYDF--FDSYIIM--EYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ KH NI LY+ F +II EYC+GGDL +KD +V K ++ Q++ A+
Sbjct: 124 KLLKHDNICRLYEMISFQDHIIFVNEYCAGGDLLRKMKD-IVAMKEEDAKFTFRQLIAAL 182
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV--GSERYMAPELFES 235
++ S I HRD+K ENI + + N+KL D+G + K + GS Y+APE+F
Sbjct: 183 THLQSYNIVHRDLKCENIFMDKHGNVKLGDFGFSRILKPGEKSGTFCGSRAYVAPEIF-- 240
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
R Y VD+W+ G+++ ++ PF
Sbjct: 241 ------RGREYSGNAVDVWSTGVILYIMLAGSMPF 269
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 83.6 bits (205), Expect = 1e-15
Identities = 60/213 (28%), Positives = 106/213 (49%), Gaps = 22/213 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFF-----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNII 170
EV I T++ +H I ++YD F D +IME GG+L++ + ++ V II
Sbjct: 90 EVSILTQL-RHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESYVLSELAVVMII 148
Query: 171 NQILDAVEYVHSRGIYHRDIKPENIL---IAGNWNIKLTDWGLATTDKTSMERN--VGSE 225
Q+ +A++Y+H + I H D+KPENI+ + GN IKL D+GLA + E G+
Sbjct: 149 CQLCEAIDYIHKQNILHLDVKPENIMCVSLTGN-RIKLIDFGLARHYDGTQELKYMAGTP 207
Query: 226 RYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAA 285
+ APE+ + E+ D + D+W+IG++ ++ +PF + + + +C
Sbjct: 208 EFAAPEVI-----KFEKLDYH----TDMWSIGVITYILLSGYSPF-LGDNLGETYCNVEK 257
Query: 286 NREALFDVFSTMSYDFFQVLRHALTIDPTNRNL 318
+ F T++ + + L D + R L
Sbjct: 258 GVWEFTEEFDTVTEEAKDFVTKLLVYDQSKRML 290
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/215 (28%), Positives = 101/215 (46%), Gaps = 29/215 (13%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I + H N+ YD ++ YI+ME C GG+L + I ++ ++
Sbjct: 199 EVKILRALSGHNNLPHFYDAYEDHDNVYIVMELCEGGELLDRILSRGGKYTEEDAKTVMI 258
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATTDKTSMERN--VGSER 226
QIL+ V + H +G+ HRD+KPEN L + +K D+GL+ + N VGS
Sbjct: 259 QILNVVAFCHLQGVVHRDLKPENFLFTSKEDTSQLKAIDFGLSDYVRPDERLNDIVGSAY 318
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ L R T+A DIW++G+++ ++ PF +T+
Sbjct: 319 YVAPEV----LHRSYSTEA------DIWSVGVIVYILLCGSRPFWA--RTESGIFRAVLK 366
Query: 287 REALFD-----VFSTMSYDFFQVLRHALTIDPTNR 316
+ FD + S+ + DF ++ L DP R
Sbjct: 367 ADPSFDDPPWPLLSSEARDF---VKRLLNKDPRKR 398
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 83.6 bits (205), Expect = 1e-15
Identities = 56/189 (29%), Positives = 96/189 (50%), Gaps = 22/189 (11%)
Query: 97 ISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYE 152
I + + R + + + E+ I +I H NI L D S ++++EYC GGDL
Sbjct: 40 IKEIAMDRLNKKLQESLMSEIFILRRIN-HPNIIRLIDMIKSPGKVHLVLEYCKGGDLSV 98
Query: 153 AI-KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDW 208
+ + +VP T + + Q+ ++ + I HRD+KP+N+L++ N N +K+ D+
Sbjct: 99 YVQRHGIVPEATAK--HFMQQLAAGLQVLRDNNIIHRDLKPQNLLLSTNENDADLKIADF 156
Query: 209 GLATT--DKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFH 266
G A + + E GS YMAPE+ + YD AK D+W++G ++ +V
Sbjct: 157 GFARSLQPRGLAETLCGSPLYMAPEIMQ--------LQKYD-AKADLWSVGAILFQLVTG 207
Query: 267 KNPFTVANQ 275
+ PFT +Q
Sbjct: 208 RTPFTGNSQ 216
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 83.6 bits (205), Expect = 1e-15
Identities = 69/238 (28%), Positives = 112/238 (46%), Gaps = 28/238 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I + NI E ++ +++ME CSGG+L++ I K NI
Sbjct: 133 EVMILQHLTGQPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKG-SYSEKEAANIFR 191
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLAT-TDKTSMERN-VGSER 226
QI++ V H G+ HRD+KPEN L+ N IK TD+GL+ ++ + R+ VGS
Sbjct: 192 QIVNVVHVCHFMGVVHRDLKPENFLLVSNEEDSPIKATDFGLSVFIEEGKVYRDIVGSAY 251
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ N +E +D+W+ G+++ ++ PF +T+K F A
Sbjct: 252 YVAPEVLHRNYGKE----------IDVWSAGVMLYILLSGVPPFW--GETEKTI--FEAI 297
Query: 287 REALFDV----FSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNS 340
E D+ + T+S ++R L DP R E +++ + D+ NS
Sbjct: 298 LEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHPWMTDTKISDKPINS 355
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 83.2 bits (204), Expect = 2e-15
Identities = 75/301 (24%), Positives = 131/301 (42%), Gaps = 36/301 (11%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
++ +E + GS G V L Q K++ +K + ++ K K +
Sbjct: 99 WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRAS--KAYLHKQHSL------------ 144
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
S + + +L+ QK L +K ++R V +L ++ I + + + + F
Sbjct: 145 ---PSPKNESEILERQKRL--EKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHF- 198
Query: 138 SYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILI 197
Y++ EY SGG L + I K + I A++Y+H+ I HRD+K ENI+I
Sbjct: 199 -YMLFEYVSGGQLLDYIIQHG-SLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMI 256
Query: 198 AGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWA 255
+ + IK+ D+GL+ + + GS + APEL + Y +VDIW+
Sbjct: 257 SSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELL--------KAQPYTGPEVDIWS 308
Query: 256 IGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTN 315
GIV+ +V K PF N + ++ D S +S + +L + +DP
Sbjct: 309 FGIVLYVLVCGKVPFDDENSS----ILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLR 364
Query: 316 R 316
R
Sbjct: 365 R 365
>YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 640
Score = 83.2 bits (204), Expect = 2e-15
Identities = 80/294 (27%), Positives = 131/294 (44%), Gaps = 54/294 (18%)
Query: 16 DRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDET 75
++Y L G +GYV A + L K+VAVK I K + + + VM +
Sbjct: 86 NQYTLGVSAGSGQFGYVRKAYSSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLWKSKG 145
Query: 76 NNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF 135
T N S + RL+ +K SR NNV +I L +
Sbjct: 146 KITTNMSGNEAMRLMNIEKCRWEIFAASRLRNNV------------------HIVRLIEC 187
Query: 136 FDS------YIIMEYCSGGDLYEAIKDD--MVPRKTKNVTN----------IINQILDAV 177
DS +I+ +CS G+L DD ++P+ K V + I+ + +
Sbjct: 188 LDSPFSESIWIVTNWCSLGELQWKRDDDEDILPQWKKIVISNCSVSTFAKKILEDMTKGL 247
Query: 178 EYVHSRGIYHRDIKPENILIAGNWNI-KLTDWG--------LATTD-------KTSMERN 221
EY+HS+G HRDIKP NIL+ + KL+D+G L +D + + +
Sbjct: 248 EYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKI 307
Query: 222 VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQ 275
VG+ ++APEL +L +R D K+DIW++G+ + +++++ PF N+
Sbjct: 308 VGTPAFIAPEL--CHLGNSKRDFVTDGFKLDIWSLGVTLYCLLYNELPFFGENE 359
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 83.2 bits (204), Expect = 2e-15
Identities = 54/197 (27%), Positives = 96/197 (48%), Gaps = 20/197 (10%)
Query: 126 HKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H +I Y+ D Y++MEY G+L++ I + ++ + ++ QI+ VEY H
Sbjct: 76 HPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDE-ARHLFQQIISGVEYCH 134
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLATT--DKTSMERNVGSERYMAPELFESNLDR 239
I HRD+KPEN+L+ NIK+ D+GL+ D ++ + GS Y APE+
Sbjct: 135 RNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYG 194
Query: 240 EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSY 299
+ VDIW+ G+++ ++ PF N + F + ++ + + +S+
Sbjct: 195 PD---------VDIWSCGVILYALLCGTLPFDDENIPN----VFEKIKRGMYTLPNHLSH 241
Query: 300 DFFQVLRHALTIDPTNR 316
++ L +DPT R
Sbjct: 242 FARDLIPRMLMVDPTMR 258
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 83.2 bits (204), Expect = 2e-15
Identities = 63/271 (23%), Positives = 112/271 (41%), Gaps = 69/271 (25%)
Query: 13 LLRDRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKD 72
+L +Y+L + GS+ V LA + +LVAVK I
Sbjct: 20 ILLGKYELGRRLGSGSFAKVHLARSIESDELVAVKII----------------------- 56
Query: 73 DETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITEL 132
E T+ S E + + E+D ++ H NI ++
Sbjct: 57 -EKKKTIESGMEPR--------------------------IIREIDAMRRLRHHPNILKI 89
Query: 133 YDFFDS----YIIMEYCSGGDLY-EAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYH 187
++ + Y++ME SGG+L+ + ++ +P T Q+ A+ + H G+ H
Sbjct: 90 HEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTAR--RYFQQLASALRFSHQDGVAH 147
Query: 188 RDIKPENILIAGNWNIKLTDWGLAT----TDKTSMERNVGSERYMAPELFESNLDREERT 243
RD+KP+N+L+ N+K++D+GL+ + G+ Y APE+
Sbjct: 148 RDVKPQNLLLDEQGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEVISRR------- 200
Query: 244 DAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
YD AK D W+ G+++ ++ PF +N
Sbjct: 201 -GYDGAKADAWSCGVILFVLLVGDVPFDDSN 230
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 82.8 bits (203), Expect = 2e-15
Identities = 52/148 (35%), Positives = 77/148 (51%), Gaps = 15/148 (10%)
Query: 129 ITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRG 184
IT+LY+ + ++ +EYC G +LY+ + + + QI AV Y HS
Sbjct: 94 ITKLYEVIVTESKVWMALEYCPGKELYDHLLS-LRRISLLECGELFAQISGAVYYAHSMH 152
Query: 185 IYHRDIKPENILIAGNWNIKLTDWGLA--TTDKTSMERNVGSERYMAPELFESNLDREER 242
HRD+K ENIL+ N N KLTD+G KT++E G+ YMAPEL E
Sbjct: 153 CVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERR------ 206
Query: 243 TDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
YD K+DIW++G+++ ++ PF
Sbjct: 207 --TYDGFKIDIWSLGVILYTLITGYLPF 232
>YCR008w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 603
Score = 82.8 bits (203), Expect = 2e-15
Identities = 61/240 (25%), Positives = 110/240 (45%), Gaps = 34/240 (14%)
Query: 63 GVMVIGDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTK 122
GV+ I +K+ + + S + + K + S ++K R ++ C +
Sbjct: 328 GVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLH------ 381
Query: 123 IGKHKNITELYDFFDSYI-----IMEYCSGGDLYEAIKDDMVPRKTKNVTN--IINQILD 175
H NI D F +MEYC+GGDL+ + + K + + Q++
Sbjct: 382 ---HTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLV---VAAGKLEYMEADCFFKQLIR 435
Query: 176 AVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV-------GSERYM 228
V Y+H G+ HRD+KPEN+L+ + +K+TD+G + K + E+N+ GS Y+
Sbjct: 436 GVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYI 495
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANRE 288
APE E + +D VDIWA G++ + + + ++ A + D + + R+
Sbjct: 496 APE--------EYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRK 547
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 82.8 bits (203), Expect = 2e-15
Identities = 56/165 (33%), Positives = 86/165 (51%), Gaps = 19/165 (11%)
Query: 116 EVDIQTKIGK--HKNITELYDFF--DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTN--- 168
E+ I + K H+NI L DFF D Y +E G+ D++ KT N+T
Sbjct: 1149 EIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKT-NMTEFEA 1207
Query: 169 --IINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS-MERNVGSE 225
I Q++ ++++H +GI HRDIK EN+++ +K+ D+G A K+ + VG+
Sbjct: 1208 KLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGTI 1267
Query: 226 RYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
Y APE+ N Y+ DIWAIGI++ +VF +NPF
Sbjct: 1268 DYAAPEVLGGN--------PYEGQPQDIWAIGILLYTVVFKENPF 1304
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 82.8 bits (203), Expect = 2e-15
Identities = 66/258 (25%), Positives = 112/258 (42%), Gaps = 65/258 (25%)
Query: 24 ISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNTVNSSQ 83
+ G +G+V LA + + +VA+K +FKS+
Sbjct: 37 LGRGKFGHVYLAREKRSNHVVALKVLFKSQ------------------------------ 66
Query: 84 EKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----Y 139
+Q ++HQ L R EV+IQ+ + +H NI LY +F Y
Sbjct: 67 -LQQSQVEHQ--------LRR-----------EVEIQSHL-RHPNILRLYGYFYDQKRVY 105
Query: 140 IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG 199
+I+EY + G+LY+ ++ + + T + + + A+ Y H + + HRDIKPEN+LI
Sbjct: 106 LILEYAARGELYKDLQKCKYFSERRAATYVAS-LARALIYCHGKHVIHRDIKPENLLIGA 164
Query: 200 NWNIKLTDWGLATTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIV 259
+K+ D+G + G+ Y+ PE+ ES A VDIW++GI+
Sbjct: 165 QGELKIADFGWSVHTFNRRRTMCGTLDYLPPEMVES---------VEHDASVDIWSLGIL 215
Query: 260 MLNIVFHKNPFTVANQTD 277
++ PF +D
Sbjct: 216 CYEFLYGVPPFEAMEHSD 233
>Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase
Length = 330
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/225 (32%), Positives = 105/225 (46%), Gaps = 23/225 (10%)
Query: 102 LSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAI--- 154
L+R S +AL E+ I + +H NI Y+ F I +EYC+GG+LY+ I
Sbjct: 85 LTRLSEKERRDALNEIVILALL-QHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKILRQ 143
Query: 155 KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA--- 211
KD + + V + QI+ AV +H GI HRDIK NI + IKL D+GLA
Sbjct: 144 KDKLFEEEM--VVWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTKANLIKLGDYGLAKKL 201
Query: 212 TTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFT 271
++ + E VG+ YM+PEL + Y+ K DIWA+G V+ ++ K F
Sbjct: 202 NSEYSMAETLVGTPYYMSPELCQG--------VKYN-FKSDIWAVGCVIFELLTLKRTFD 252
Query: 272 VANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
N + R D S S + Q++ L DP R
Sbjct: 253 ATNPLNLCVKIVQGIRAMEVD-SSQYSLELIQMVHSCLDQDPEQR 296
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 82.4 bits (202), Expect = 3e-15
Identities = 78/337 (23%), Positives = 149/337 (44%), Gaps = 75/337 (22%)
Query: 16 DRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDET 75
D + L++ + +G++G V L+ +L A+K + KD ++
Sbjct: 822 DNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVL----------KKDNII---------Q 862
Query: 76 NNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF 135
N+ + S++ +K+ L K+ KH +T LY
Sbjct: 863 NHDIESARAEKKVFLLATKT-----------------------------KHPFLTNLYCS 893
Query: 136 FDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIK 191
F + Y ME+ GGDL +++ + + ++L A++Y H G+ +RD+K
Sbjct: 894 FQTENRIYFAMEFIGGGDLMWHVQNQRL--SVRRAKFYAAEVLLALKYFHDNGVIYRDLK 951
Query: 192 PENILIAGNWNIKLTDWGLATTDKTSMERN---VGSERYMAPELFESNLDREERTDAYDC 248
ENIL+ +IK+ D+GL + R G+ +MAPE+ L +E T A
Sbjct: 952 LENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEI----LKEQEYTKA--- 1004
Query: 249 AKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHA 308
VD WA G+++ ++ ++PF+ + D+ F + E L+ + M+ + Q+ +
Sbjct: 1005 --VDWWAFGVLLYQMLLCQSPFS-GDDEDEVFNAILTD-EPLYPI--DMAGEIVQIFQGL 1058
Query: 309 LTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSLDSDE 345
LT DP EK R ++ M++ ++ +++ D+
Sbjct: 1059 LTKDP-----EKRLGAGPRDADEVMEEPFFRNINFDD 1090
>SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 903
Score = 82.4 bits (202), Expect = 3e-15
Identities = 52/141 (36%), Positives = 77/141 (53%), Gaps = 25/141 (17%)
Query: 139 YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIA 198
YI MEYC L + I+D + + + QIL+A+ Y+HSRG+ HRD+KP NI +
Sbjct: 725 YIQMEYCEKLSLQDIIRDKI---PVDEMWRLFRQILEALAYIHSRGMMHRDLKPGNIFLD 781
Query: 199 GNWNIKLTDWGLATTDKTSMERN----------------VGSERYMAPELFESNLDREER 242
N N+KL D+GLAT ++ + N VG+ Y+APEL L R
Sbjct: 782 ENRNVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPEL----LSRRNG 837
Query: 243 TDAYDCAKVDIWAIGIVMLNI 263
YD AKVD++++GI++ +
Sbjct: 838 V-RYD-AKVDMYSLGIILFEM 856
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 82.4 bits (202), Expect = 3e-15
Identities = 46/161 (28%), Positives = 87/161 (53%), Gaps = 10/161 (6%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E I ++ H +I L D ++S +++ + G+L++ + + V K +I+
Sbjct: 77 ETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEK-VALSEKETRSIMR 135
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA--TTDKTSMERNVGSERYMA 229
+L+AV ++H+ I HRD+KPENIL+ N I+L+D+G + + G+ Y+A
Sbjct: 136 SLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLA 195
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
PE+ + ++D E Y +VD+WA G+++ ++ PF
Sbjct: 196 PEILKCSMD--ETHPGYG-KEVDLWACGVILFTLLAGSPPF 233
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 82.4 bits (202), Expect = 3e-15
Identities = 58/208 (27%), Positives = 98/208 (46%), Gaps = 20/208 (9%)
Query: 122 KIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAV 177
K+ +H NI LY+ D+ Y+I+E GD+++ I QI+ A+
Sbjct: 68 KLVQHPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAI 127
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN-IKLTDWGLATTDKTS--MERNVGSERYMAPELFE 234
Y H + HRD+KPEN++ +KLTD+G + + + + GS Y APE+
Sbjct: 128 SYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILL 187
Query: 235 SNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVF 294
D YD VDIW++G+++ +V + PF AN ++ + + V
Sbjct: 188 G--------DEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSET----LTMIMDCKYTVP 235
Query: 295 STMSYDFFQVLRHALTIDPTNR-NLEKV 321
S +S + ++ L DP R +LE++
Sbjct: 236 SHVSKECKDLITRMLQRDPKRRASLEEI 263
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 82.4 bits (202), Expect = 3e-15
Identities = 64/210 (30%), Positives = 105/210 (49%), Gaps = 36/210 (17%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
KH NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+AV
Sbjct: 69 KHSNIVRLHDSISEEGFHYLVFDLVTGGELFE----DIVAREYYSEADASHCIQQILEAV 124
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATT---DKTSMERNVGSERYMAPE 231
+ H G+ HRD+KPEN+L+A +KL D+GLA D+ + G+ Y++PE
Sbjct: 125 LHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE 184
Query: 232 LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTD-----KAFCYFAAN 286
+ R +AY VDIWA G+++ ++ PF +Q KA Y +
Sbjct: 185 VL--------RKEAYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
Query: 287 REALFDVFSTMSYDFFQVLRHALTIDPTNR 316
E + T++ + ++ LTI+P R
Sbjct: 236 PE-----WDTVTPEAKNLINQMLTINPAKR 260
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 82.4 bits (202), Expect = 3e-15
Identities = 55/185 (29%), Positives = 90/185 (47%), Gaps = 20/185 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDSY----IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E++I ++ H N+ +LYD F+S ++MEY GG+L++ I D+ +V
Sbjct: 536 EINIMNQLS-HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTR 594
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG--NWNIKLTDWGLATTDK--TSMERNVGSERY 227
QI + V Y+H I H D+KPENIL IK+ D+GLA K ++ N G+ +
Sbjct: 595 QICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEF 654
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANR 287
+APE+ + D+W++G++ ++ +PF +TD F N
Sbjct: 655 LAPEVVNYE---------FVSFPTDMWSVGVITYMLLSGLSPF--LGETDAETMNFIVNC 703
Query: 288 EALFD 292
FD
Sbjct: 704 SWDFD 708
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 82.4 bits (202), Expect = 3e-15
Identities = 57/208 (27%), Positives = 102/208 (48%), Gaps = 21/208 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E++I + + KH NI +Y F Y+I+EY G+ ++ + D K + I
Sbjct: 58 EIEIHSNL-KHPNILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSLYIR 116
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTD--WGLATTDKTSMERNVGSERYMA 229
Q++ A+ Y+ + HRDIKPEN+L+ + +K+ D W + DK M G+ Y+A
Sbjct: 117 QVMLALTYMKECNVIHRDIKPENLLLGSDNQLKIADFGWAVYNADKRRM-TFCGTMEYLA 175
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQT-DKAFCYFAANRE 288
PE+ + D +D + +D+W +GI+ + K PF N+ +A+ + +
Sbjct: 176 PEMVNN--------DIHD-SGIDLWCLGILTYEFLMGKTPFESKNRNMREAYKKINSLKY 226
Query: 289 ALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ + S+ + DF L L + P +R
Sbjct: 227 TIPETISSNASDFISRL---LVLSPGDR 251
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 82.4 bits (202), Expect = 3e-15
Identities = 60/208 (28%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
+H NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL+++
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFE----DIVAREFYSEADASHCIQQILESI 122
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLA--TTDKTSMERNVGSERYMAPEL 232
Y HS GI HRD+KPEN+L+A +KL D+GLA D + G+ Y++PE+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEV 182
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
+ D Y VDIWA G+++ ++ PF +Q +A + +D
Sbjct: 183 L--------KKDPYS-KPVDIWACGVILYILLVGYPPFWDEDQ----HRLYAQIKAGAYD 229
Query: 293 V----FSTMSYDFFQVLRHALTIDPTNR 316
+ T++ + ++ LT++P R
Sbjct: 230 YPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 82.4 bits (202), Expect = 3e-15
Identities = 92/353 (26%), Positives = 149/353 (42%), Gaps = 101/353 (28%)
Query: 13 LLRDR-----YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVI 67
LL+DR +++I+ IS G++G V LA A+K + K + + ND
Sbjct: 660 LLKDRISIDDFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDI------- 712
Query: 68 GDEKDDETNNTVNSSQEKKQRLLKHQKSLISDK---VLSRFSNNVCFEALYEVDIQTKIG 124
+R+L+ + LI+ + ++ F + C + LY
Sbjct: 713 -------------------ERILQERNILITVRYPFLVRFFYSFTCRDNLY--------- 744
Query: 125 KHKNITELYDFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNI-INQILDAVEYVHSR 183
++MEY +GGDLY ++ V + + I I +++ A+EY+HS
Sbjct: 745 ---------------LVMEYLNGGDLYSLLQK--VGCLDEEIARIYIAELVLALEYLHSL 787
Query: 184 GIYHRDIKPENILIAGNWNIKLTDWGLA-------TTDKTSMERN--------------- 221
I HRD+KP+N+LIA N +IKLTD+GL+ T D + E +
Sbjct: 788 KIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGLINNTIDLSGHESDVSPRTNSHHFQKNQE 847
Query: 222 --------VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVA 273
VG+ Y+APE+ L E A D W+ GIV+ ++ PFT A
Sbjct: 848 EERIRHSAVGTPDYLAPEIL---LGTEHGYAA------DWWSAGIVLFELLTGIPPFT-A 897
Query: 274 NQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIK 326
++ +K F + DV MSY+ ++ L +P R E+K
Sbjct: 898 SRPEKIFDNILNGKMPWPDVPGEMSYEAQDLINRLLVHEPEKRLGANGAAEVK 950
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 82.0 bits (201), Expect = 3e-15
Identities = 67/224 (29%), Positives = 112/224 (49%), Gaps = 26/224 (11%)
Query: 107 NNVCFEALYE-VDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPR 161
NNV + LYE + I K+ H NI D+F+S YI+ + +GG+L++ I
Sbjct: 86 NNVQLQMLYEELSILQKLS-HPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFT 144
Query: 162 KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILI---AGNWNIKLTDWGLATT---DK 215
+ V II QIL AVEY+HS+ + HRD+KPEN+L + N + + D+G+A ++
Sbjct: 145 EVDAV-EIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEE 203
Query: 216 TSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQ 275
+ + GS Y+APE+ T DIW+IG++ ++ +PF +A
Sbjct: 204 DLIYKAAGSLGYVAPEVL---------TQDGHGKPCDIWSIGVITYTLLCGYSPF-IAES 253
Query: 276 TDKAFCYFAANREAL---FDVFSTMSYDFFQVLRHALTIDPTNR 316
+ A+R + + +S D + + AL ++P +R
Sbjct: 254 VEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADR 297
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 82.0 bits (201), Expect = 3e-15
Identities = 75/301 (24%), Positives = 134/301 (43%), Gaps = 36/301 (11%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
++ +E + GS G V LA ++ AVK + ++ K K+ ++
Sbjct: 120 WEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRAT--KAFLHKEQML------------ 165
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
+ +Q +L+ QK L +K +SR + +L ++ I + + L + F
Sbjct: 166 ---PPPKNEQDVLERQKKL--EKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHF- 219
Query: 138 SYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILI 197
Y++ EY SGG L + I R+ + I A+ Y+H+ I HRD+K ENI+I
Sbjct: 220 -YMLFEYVSGGQLLDYIIQHGSIREHQ-ARKFARGIASALIYLHANNIVHRDLKIENIMI 277
Query: 198 AGNWNIKLTDWGLAT--TDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWA 255
+ + IK+ D+GL+ + + GS + APEL ++N Y +VD+W+
Sbjct: 278 SDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKAN--------PYTGPEVDVWS 329
Query: 256 IGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTN 315
G+V+ +V K PF N + ++ + +S + +L L +DP
Sbjct: 330 FGVVLFVLVCGKVPFDDENSS----VLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKR 385
Query: 316 R 316
R
Sbjct: 386 R 386
>CE27573 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1420
Score = 82.0 bits (201), Expect = 3e-15
Identities = 57/167 (34%), Positives = 85/167 (50%), Gaps = 16/167 (9%)
Query: 126 HKNITELY----DFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H+N+ + Y + D I MEYCS G L M K V N +L AV+Y+H
Sbjct: 1178 HENLVKYYGVQVEDSDVIIFMEYCSQGTLERICHGKM---DLKMVRQYTNSLLRAVQYLH 1234
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGL------ATTDKTSMERNVGSERYMAPELFES 235
S I HRDIKP NI + +KL D+G ++T + G+ ++MAPE++ S
Sbjct: 1235 SHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVESSTVYGEFQTTAGTPQFMAPEIY-S 1293
Query: 236 NLDREERTDAYD--CAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAF 280
+++E T +Y VDIWA+G ++N++ K PF + AF
Sbjct: 1294 YGEKDETTGSYSGYGRSVDIWALGATVVNMMTGKVPFEGQTRHQIAF 1340
>CE07737 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1418
Score = 82.0 bits (201), Expect = 3e-15
Identities = 57/167 (34%), Positives = 85/167 (50%), Gaps = 16/167 (9%)
Query: 126 HKNITELY----DFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H+N+ + Y + D I MEYCS G L M K V N +L AV+Y+H
Sbjct: 1178 HENLVKYYGVQVEDSDVIIFMEYCSQGTLERICHGKM---DLKMVRQYTNSLLRAVQYLH 1234
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGL------ATTDKTSMERNVGSERYMAPELFES 235
S I HRDIKP NI + +KL D+G ++T + G+ ++MAPE++ S
Sbjct: 1235 SHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVESSTVYGEFQTTAGTPQFMAPEIY-S 1293
Query: 236 NLDREERTDAYD--CAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAF 280
+++E T +Y VDIWA+G ++N++ K PF + AF
Sbjct: 1294 YGEKDETTGSYSGYGRSVDIWALGATVVNMMTGKVPFEGQTRHQIAF 1340
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 82.0 bits (201), Expect = 3e-15
Identities = 49/159 (30%), Positives = 81/159 (50%), Gaps = 19/159 (11%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
+H +I L++ + + +ME+ GG+L+ + Q++ AV Y
Sbjct: 78 RHPSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGRFCEDLSR--RYFQQLISAVGYC 135
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGL-ATTDKTS----MERNVGSERYMAPELFES 235
HSRGI+HRD+KPEN+L+ ++K++D+GL A TD+ + G+ Y+APE+
Sbjct: 136 HSRGIFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAK 195
Query: 236 NLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
YD AK+DIW+ GI++ + PF N
Sbjct: 196 K--------GYDGAKIDIWSCGIILFVLNAGYLPFNDHN 226
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 81.6 bits (200), Expect = 5e-15
Identities = 64/205 (31%), Positives = 98/205 (47%), Gaps = 32/205 (15%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCS 146
K+ ++S + L R V + + ++ +Q K+ K I +L+ F Y ++EY
Sbjct: 150 KYAVKVLSKEYLIR-QKKVKYVTVEKLALQ-KLNGTKGIFKLFFTFQDEASLYFLLEYAP 207
Query: 147 GGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLT 206
GD IK +T +QI+DAV+ +H+ GI HRDIKPENIL+ N +KLT
Sbjct: 208 HGDFLGLIKKYGSLNETC-ARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLT 266
Query: 207 DWGLA---------TTD-------KTSMERNVGSERYMAPELFESNLDREERTDAYDCAK 250
D+G A T D + VG+ Y++PEL N Y ++
Sbjct: 267 DFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDN---------YTDSR 317
Query: 251 VDIWAIGIVMLNIVFHKNPFTVANQ 275
DIWA G ++ ++ K PF AN+
Sbjct: 318 CDIWAFGCILYQMLAGKPPFKAANE 342
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 414
Score = 81.6 bits (200), Expect = 5e-15
Identities = 56/191 (29%), Positives = 100/191 (52%), Gaps = 25/191 (13%)
Query: 128 NITELYDFFDSYI-IMEYCSGGDLYE-AIKDDMVPRKTKNVTNIINQILDAVEYVHSRGI 185
N+ E+Y+ I ++EY +GG++++ + D K K+V ++ QIL+ V ++H+R +
Sbjct: 123 NLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDV 182
Query: 186 YHRDIKPENILIAGN---WNIKLTDWGLATTDKTSMERN--VGSERYMAPELFESNLDRE 240
H D+KP+NIL+ +IK+ D+GL+ K S E +G+ Y+APE+
Sbjct: 183 VHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEIL------- 235
Query: 241 ERTDAYD--CAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFA----ANREALFDVF 294
+YD D+W+IG++ ++ +PF + N + F + + E FDV
Sbjct: 236 ----SYDPISMATDMWSIGVLTYVMLTGISPF-LGNDKQETFLNISQMNLSYSEEEFDVL 290
Query: 295 STMSYDFFQVL 305
S + DF + L
Sbjct: 291 SESAVDFIRTL 301
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 81.6 bits (200), Expect = 5e-15
Identities = 68/267 (25%), Positives = 124/267 (45%), Gaps = 45/267 (16%)
Query: 106 SNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPR 161
S +A E I + H NI +L+D Y++ME +G +L E I+ + R
Sbjct: 414 SQKFASQAQREARILEMVQGHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRK--LER 471
Query: 162 KTKN-VTNIINQILDAVEYVHSRGIYHRDIKPENIL---IAGNWNIKLTDWGLATTDKTS 217
T++ +I+ Q++ AV+Y+H + I HRD+KPENIL I + ++L D+G A S
Sbjct: 472 FTESEAADIMRQLVSAVKYLHDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPNS 531
Query: 218 MERNVGSE-------------------------RYMAPELFESNLDREERTDAYDCAKVD 252
ME+ + S +Y APE+ + + E + + D
Sbjct: 532 MEQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNE-----QCD 586
Query: 253 IWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALF----DVFSTMSYDFFQVLRHA 308
+W++G+V+ ++ + PF ++ + A A F D ++ +S D ++
Sbjct: 587 LWSLGVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGL 646
Query: 309 LTIDPTNR-NLEKVRTEIKRLSEYTMD 334
LT+DP R +++++ + S +MD
Sbjct: 647 LTVDPKKRLSMQELTAHMWLKSSASMD 673
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/142 (27%), Positives = 73/142 (50%), Gaps = 20/142 (14%)
Query: 139 YIIMEYCSGGDLYEAIKD----DMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPEN 194
+I+MEY GG+L+ + D+ + +I +++ A++ +H R + +RD+K EN
Sbjct: 96 HIVMEYVRGGELFTHLCSRGHFDLEAARF-----VIAELVVAIDSLHQRKVIYRDLKLEN 150
Query: 195 ILIAGNWNIKLTDWGLATT----DKTSMERNVGSERYMAPELFESNLDREERTDAYDCAK 250
IL+ ++KLTD+GL+ + G+ YM+PE+ R +
Sbjct: 151 ILLDEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMSPEVI-------NRPEGGYSDV 203
Query: 251 VDIWAIGIVMLNIVFHKNPFTV 272
VD W++G++ ++ +PFTV
Sbjct: 204 VDWWSLGVISFELLTGCSPFTV 225
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 81.6 bits (200), Expect = 5e-15
Identities = 58/213 (27%), Positives = 102/213 (47%), Gaps = 26/213 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPR---KTKNVTN 168
EV+I ++ +H NI L + ++ +++ME C GG+L++ I V R + +
Sbjct: 102 EVEIMRQMPEHPNIVTLKETYEDDKAVHLVMELCEGGELFDRI----VARGHYTERAAAS 157
Query: 169 IINQILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDKTSMERN--VG 223
+I I++ V+ H G+ HRD+KPEN L A ++K D+GL+ K N VG
Sbjct: 158 VIKTIIEVVQMCHKHGVMHRDLKPENFLFANKKETASLKAIDFGLSVFFKPGERFNEIVG 217
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYF 283
S YMAPE+ + +E +DIW+ G+++ ++ PF + A
Sbjct: 218 SPYYMAPEVLRRSYGQE----------IDIWSAGVILYILLCGVPPFWAETEHGVAKAIL 267
Query: 284 AANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ + D + +S + +++ L DP R
Sbjct: 268 KSVIDFKRDPWPKVSDNAKDLIKKMLHPDPRRR 300
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 81.6 bits (200), Expect = 5e-15
Identities = 61/194 (31%), Positives = 95/194 (48%), Gaps = 29/194 (14%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I ++ KH NI L + D Y++ME GGDL++AI + ++ + ++
Sbjct: 92 EVSILRRV-KHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTE-RDASGMLY 149
Query: 172 QILDAVEYVHSRGIYHRDIKPENILI----AGNWNIKLTDWGLATTDKTSMERNVGSERY 227
+ A++Y+HS I HRDIKPEN+L+ G+ ++KL D+GLAT + G+ Y
Sbjct: 150 NLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTY 209
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANR 287
+APE+ Y KVDIWA G++ ++ PF + ++
Sbjct: 210 VAPEIIAET--------GYG-LKVDIWAAGVITYILLCGFPPFRGSGD----------DQ 250
Query: 288 EALFDVFSTMSYDF 301
E LFD DF
Sbjct: 251 EVLFDQILMGQVDF 264
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 81.3 bits (199), Expect = 6e-15
Identities = 68/218 (31%), Positives = 110/218 (50%), Gaps = 22/218 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+++ K+ H I L F++ Y++ME+ SGGDL + + + I
Sbjct: 244 ELEVLQKLN-HPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAG-REISR 301
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGN--WNIKLTDWGLATT--DKTSMERNVGSERY 227
QIL A++Y+HS GI HRD+KP+NILI + +K+TD+GLA + + M+ G+ Y
Sbjct: 302 QILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAY 361
Query: 228 MAPELFESNLDREERTDAYD-----CAKVDIWAIGIVMLNIVFHKNPFTVANQTD--KAF 280
+APE+ D D Y+ + VD+W++G ++ I+ PF+ + Q K
Sbjct: 362 VAPEVIRGK-DTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQI 420
Query: 281 CYFAANREALFDV-FSTMSYDFFQVLRHALTIDPTNRN 317
+ + L D S + DF L L +DP NR+
Sbjct: 421 GRGSYHEGPLKDFRISEEARDFIDSL---LQVDPNNRS 455
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 81.3 bits (199), Expect = 6e-15
Identities = 51/162 (31%), Positives = 82/162 (50%), Gaps = 17/162 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ + + NIT Y + +IIME+C+GG L ++ + K V I+
Sbjct: 69 EIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGV--IMR 126
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT-TDKTSMERN--VGSERYM 228
++L A++ +H + HRDIK N+LI N+KL D+G+A ++TS+ R G+ +M
Sbjct: 127 ELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWM 186
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
APE+ + Y KVDIW++GI I P+
Sbjct: 187 APEVIMEGV--------YYDTKVDIWSLGITTYEIATGNPPY 220
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 81.3 bits (199), Expect = 6e-15
Identities = 61/181 (33%), Positives = 101/181 (55%), Gaps = 23/181 (12%)
Query: 91 KHQKSLISDKVLSRFSNNVCF--EALYEVDIQTKIGKHKNITELYDF-FDS---YIIMEY 144
K + +++ K +++ S N L E++I I +H +I +L DF +DS Y+IME+
Sbjct: 78 KDTREVVAIKCVAKKSLNKASVENLLTEIEILKGI-RHPHIVQLKDFQWDSDNIYLIMEF 136
Query: 145 CSGGDLYEAIKDDMV-PRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG--NW 201
C+GGDL I + P K V + Q+ A++++H R I H D+KP+NIL++
Sbjct: 137 CAGGDLSRFIHTRRILPEKVARV--FMQQLASALQFLHERNISHLDLKPQNILLSSLEKP 194
Query: 202 NIKLTDWGLATTDKTSMERNV--GSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIV 259
++KL D+G A E++V GS YMAPE+ YD A+VD+W++G++
Sbjct: 195 HLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQR--------QYD-ARVDLWSMGVI 245
Query: 260 M 260
+
Sbjct: 246 L 246
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 81.3 bits (199), Expect = 6e-15
Identities = 54/180 (30%), Positives = 86/180 (47%), Gaps = 19/180 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV + + H ++ + YD F+ +++ME C GG+L ++I I+
Sbjct: 193 EVKLLKALSGHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGGRYPEAEAKRILV 252
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATTDKTSMERN--VGSER 226
QIL A + H +G+ HRD+KPEN L +K+ D+GL+ + N VGS
Sbjct: 253 QILSATAFFHLQGVVHRDLKPENFLFTSKNEDAVLKVIDFGLSDYARFDQRLNDVVGSAY 312
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ L R T+A DIW+IG++ ++ PF ++ C AN
Sbjct: 313 YVAPEV----LHRSYSTEA------DIWSIGVISYILLCGSRPFYGRTESAIFRCVLRAN 362
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 81.3 bits (199), Expect = 6e-15
Identities = 80/310 (25%), Positives = 132/310 (41%), Gaps = 62/310 (20%)
Query: 17 RYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETN 76
R+ IE I GS+G V A D L K VA+K I E + DE +D
Sbjct: 14 RFSQIELIGRGSFGDVYKAFDKDLNKEVAIKVIDLEESE-------------DEIEDIQK 60
Query: 77 NTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF 136
SQ + + ++ S + QTK+
Sbjct: 61 EISVLSQCRCPYITEYYGSYLH---------------------QTKL------------- 86
Query: 137 DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
+IIMEY +GG + + ++ + P ++ I +L AVEY+H+ G HRDIK NIL
Sbjct: 87 --WIIMEYMAGGSVADLLQSNN-PLDETSIACITRDLLHAVEYLHNEGKIHRDIKAANIL 143
Query: 197 IAGNWNIKLTDWGLATTDKTSMERN---VGSERYMAPELFESNLDREERTDAYDCAKVDI 253
++ N ++K+ D+G++ ++ R VG+ +MAPE+ +++ E K DI
Sbjct: 144 LSENGDVKVADFGVSAQLTRTISRRKTFVGTPFWMAPEVIQNSEGYNE--------KADI 195
Query: 254 WAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQV-LRHALTID 312
W++GI ++ + + P + F L + FS +F + L+ A
Sbjct: 196 WSLGITVIEMAKGEPPLADLHPMRVLFIIPRETPPQLDEHFSRQVKEFVSLCLKKAPAER 255
Query: 313 PTNRNLEKVR 322
P+ + L K R
Sbjct: 256 PSAKELIKHR 265
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 81.3 bits (199), Expect = 6e-15
Identities = 70/256 (27%), Positives = 114/256 (44%), Gaps = 61/256 (23%)
Query: 17 RYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETN 76
R+ E I GS+G V A DT+L K VA+K I E + DE +D
Sbjct: 341 RFSQFELIGRGSFGDVYKAFDTELNKDVAIKVIDLEESE-------------DEIEDIQK 387
Query: 77 NTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF 136
SQ + + ++ S + QTK+
Sbjct: 388 EISVLSQCRCPYITEYYGSYLH---------------------QTKL------------- 413
Query: 137 DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
+IIMEY +GG + + ++ P ++ I +L AVEY+H+ G HRDIK NIL
Sbjct: 414 --WIIMEYMAGGSVADLLQPGN-PLDEISIACITRDLLHAVEYLHAEGKIHRDIKAANIL 470
Query: 197 IAGNWNIKLTDWGLATTDKTSMERN---VGSERYMAPELFESNLDREERTDAYDCAKVDI 253
++ N ++K+ D+G++ ++ R VG+ +MAPE+ +++ E K DI
Sbjct: 471 LSENGDVKVADFGVSAQLTRTISRRKTFVGTPFWMAPEVIQNSEGYNE--------KADI 522
Query: 254 WAIGIVMLNIVFHKNP 269
W++GI M+ + + P
Sbjct: 523 WSLGITMIEMAKGEPP 538
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 81.3 bits (199), Expect = 6e-15
Identities = 54/195 (27%), Positives = 87/195 (43%), Gaps = 35/195 (17%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVP---RKTKNVTN 168
EV+I + H + L+ ++ +++ME CSGG L D MV + N
Sbjct: 148 EVEIMQHLSGHPRVVTLHAVYEESDCFHLVMELCSGGRLI----DQMVKVGRYSEQRAAN 203
Query: 169 IINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA--TTDKTSMERNVGSER 226
I ++ + Y H G+ HRDIKPENIL+ I+L D+GLA ++ GS
Sbjct: 204 IFKDLMLVINYCHEMGVVHRDIKPENILLTAAGKIQLADFGLAMRIAKGQTLSGLAGSPA 263
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ N KVD+W+ G+++ ++ PF +
Sbjct: 264 YVAPEVLSENYSE----------KVDVWSAGVLLYALLSGVLPFK------------GDS 301
Query: 287 REALFDVFSTMSYDF 301
+A+F+ + DF
Sbjct: 302 LDAIFEAIKNVKLDF 316
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 81.3 bits (199), Expect = 6e-15
Identities = 53/193 (27%), Positives = 97/193 (49%), Gaps = 19/193 (9%)
Query: 91 KHQKSLISDKVLSRFS---NNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIME 143
K + +++ KVL + +NV + E++IQ+ + +H +I LY +F Y+I+E
Sbjct: 174 KESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHL-RHPHILRLYAYFHDDVRIYLILE 232
Query: 144 YCSGGDLYEAIKDDMVPR-KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWN 202
Y G L+ A++ + R + I + A+ Y+H R I HRDIKPEN+L+
Sbjct: 233 YAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGV 292
Query: 203 IKLTDWGLATTDKTSMERNV-GSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVML 261
+K+ D+G + + SM + G+ Y+ PE+ + + VD+W++G++
Sbjct: 293 LKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKPHTK---------NVDLWSLGVLCF 343
Query: 262 NIVFHKNPFTVAN 274
++ PF N
Sbjct: 344 ELLVGHAPFYSKN 356
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 80.9 bits (198), Expect = 8e-15
Identities = 54/167 (32%), Positives = 91/167 (54%), Gaps = 23/167 (13%)
Query: 116 EVDIQTKIGKH--KNITELYDFF--DSYIIMEYCSGG-----DLYEAI--KDDMVPRKTK 164
E+ I + K+ +NI +L DFF D Y +E G DL++ I K DMV + K
Sbjct: 894 EIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAK 953
Query: 165 NVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS-MERNVG 223
V Q++ +++++H +GI HRDIK EN+++ + +KL D+G A K+ + VG
Sbjct: 954 LV---FKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVG 1010
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
+ Y APE+ + +Y DIWA+G+++ I++ +NP+
Sbjct: 1011 TMDYAAPEVLGGS--------SYKGKPQDIWALGVLLYTIIYKENPY 1049
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 80.9 bits (198), Expect = 8e-15
Identities = 70/255 (27%), Positives = 119/255 (46%), Gaps = 33/255 (12%)
Query: 32 VSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNTVNSSQEKKQRLLK 91
+S+ DT + ++ + + I++ + G ++GD + + V + + L +
Sbjct: 18 MSVGMDTFIHRIDSTEVIYQPRRKRAKLI--GKYLMGDLLGEGSYGKVKEVLDS-ETLCR 74
Query: 92 HQKSLISDKVLSRFSNNVCFEALYEVDIQT-KIGKHKNITELYDFFDS------YIIMEY 144
++ K L R N EA + +IQ + +HKN+ +L D + Y++MEY
Sbjct: 75 RAVKILKKKKLRRIPNG---EANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEY 131
Query: 145 CSGGDLYEAIKDDMVPRKTKNVTNIIN---QILDAVEYVHSRGIYHRDIKPENILIAGNW 201
C G + E + D VP K V Q++D +EY+HS+GI H+DIKP N+L+
Sbjct: 132 CVCG-MQEML--DSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGG 188
Query: 202 NIKLTDWGLA------TTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWA 255
+K++D G+A D T + GS + PE+ D + KVDIW+
Sbjct: 189 TLKISDLGVAEALHPFAADDT-CRTSQGSPAFQPPEIANG-------LDTFSGFKVDIWS 240
Query: 256 IGIVMLNIVFHKNPF 270
G+ + NI PF
Sbjct: 241 AGVTLYNITTGLYPF 255
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 80.9 bits (198), Expect = 8e-15
Identities = 54/199 (27%), Positives = 98/199 (49%), Gaps = 19/199 (9%)
Query: 125 KHKNITE-----LYDFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEY 179
+H N+ L D D +++M+Y GG+L + + + + ++ + L A+ +
Sbjct: 161 RHPNLVNYIESYLVDADDLWVVMDYLEGGNLTDVVVKTELDEG--QIAAVLQECLKALHF 218
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN--VGSERYMAPELFESNL 237
+H I HRDIK +N+L+ N +KLTD G + +R+ VG+ +M+PE+ L
Sbjct: 219 LHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEI----L 274
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
++++ KVDIW++GI+ L ++ + P+ + KA A N + +
Sbjct: 275 NKKQYN-----YKVDIWSLGIMALEMIDGEPPY-LRETPLKAIYLIAQNGKPEIKQRDRL 328
Query: 298 SYDFFQVLRHALTIDPTNR 316
S +F L L +DP R
Sbjct: 329 SSEFNNFLDKCLVVDPDQR 347
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 80.5 bits (197), Expect = 1e-14
Identities = 79/279 (28%), Positives = 126/279 (44%), Gaps = 66/279 (23%)
Query: 13 LLRDRYKLIEDISEGSYGYVSLASDTQ---LKKLVAVKYIFKSEDDKGNDTKDGVMVIGD 69
+ DRY + + + +GS+G V LA + L + VAVK + S
Sbjct: 16 IFEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNS----------------- 58
Query: 70 EKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNI 129
S + K LLK ++SL L + S + C L E T + ++NI
Sbjct: 59 -----------SKPKPKHELLKLRESL----ALRKISKHPCLIDLLE----TFMDPYRNI 99
Query: 130 TELYDFFDSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRD 189
+ +F D C+ L++ + + ++T NI+ QI+ +E++H G HRD
Sbjct: 100 FLVMEFMD-------CNLFQLFKRRQGRLFTKET--AFNILLQIISGIEHIHKHGFMHRD 150
Query: 190 IKPENIL--------IAGNWNIKLTDWGLATTDKTS--MERNVGSERYMAPELFESNLDR 239
IKPENIL I+ ++IKL D+GLA +S + V + Y APEL
Sbjct: 151 IKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRWYRAPELL------ 204
Query: 240 EERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDK 278
R+ +Y+ VD++A G ++ I K F N+TD+
Sbjct: 205 -LRSGSYN-HSVDLYAFGCIVFEIYSLKPLFPGRNETDQ 241
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 80.5 bits (197), Expect = 1e-14
Identities = 64/213 (30%), Positives = 106/213 (49%), Gaps = 25/213 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV+I +I +H NI L+D F D +I+E SGG+L++ + + + + T +
Sbjct: 64 EVNILREI-RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDE-ATQFLK 121
Query: 172 QILDAVEYVHSRGIYHRDIKPENILI----AGNWNIKLTDWGLATTDKTSME-RNV-GSE 225
QILD V Y+HS+ I H D+KPENI++ N IKL D+G+A + E +N+ G+
Sbjct: 122 QILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTP 181
Query: 226 RYMAPELFESNLDREERTDAYD--CAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYF 283
++APE+ Y+ + D+W+IG++ ++ +PF + +
Sbjct: 182 EFVAPEIVN-----------YEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNIS 230
Query: 284 AANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
A N + + FS S +R L DP R
Sbjct: 231 AVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRR 263
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 80.5 bits (197), Expect = 1e-14
Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 17/154 (11%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKN-VTNIINQILDAVEY 179
KH NI + F++ YI+MEYC GGDL + IK ++ + N Q+ V +
Sbjct: 58 KHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNH 117
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSME---RNVGSERYMAPELFESN 236
+H + + HRDIK +NI + N +KL D+G A M VG+ Y+ PE++E N
Sbjct: 118 IHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWE-N 176
Query: 237 LDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
L K DIW++G ++ + K+PF
Sbjct: 177 LPYNN--------KSDIWSLGCILYELCTLKHPF 202
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 80.5 bits (197), Expect = 1e-14
Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 22/196 (11%)
Query: 126 HKNITELYDFFDSY-----IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
HKNI ++Y+ +S ++ME GGD+++ + + P + Q+++A+ Y
Sbjct: 67 HKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGG-PLPESRAKALFRQMVEAIRYC 125
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLA----TTDKTSMERNVGSERYMAPELFESN 236
H G+ HRD+K EN L+ G +N+KLTD+G A + + + GS Y APE+ +
Sbjct: 126 HGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQG- 183
Query: 237 LDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFST 296
+D K D+W++G+V+ ++ PF + TD + + F +
Sbjct: 184 -------IPHDSKKGDVWSMGVVLYVMLCASLPF---DDTDIPKMLWQQQKGVSFPTHLS 233
Query: 297 MSYDFFQVLRHALTID 312
+S D +L+ L D
Sbjct: 234 ISADCQDLLKRLLEPD 249
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 80.5 bits (197), Expect = 1e-14
Identities = 62/250 (24%), Positives = 114/250 (44%), Gaps = 50/250 (20%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
++LIE + G+YG V + +L A+K +M I ++++DE
Sbjct: 21 FELIEVVGNGTYGQVYKGRHVKTAQLAAIK----------------IMNINEDEEDEIKL 64
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
+N L KH S N + + + + GKH +
Sbjct: 65 EINM-------LKKH----------SHHRNVATYYGAFIKKLPSSTGKHDQL-------- 99
Query: 138 SYIIMEYCSGGDLYEAIKDDMVPR-KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
+++ME+C G + + +K+ K + + I +IL + ++H + HRDIK +N+L
Sbjct: 100 -WLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVL 158
Query: 197 IAGNWNIKLTDWGL-ATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKVDI 253
+ + +KL D+G+ A DKT RN +G+ +MAPE+ +E +A ++ D+
Sbjct: 159 LTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIAC----DESPEATYDSRSDL 214
Query: 254 WAIGIVMLNI 263
W++GI L +
Sbjct: 215 WSLGITALEM 224
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 80.5 bits (197), Expect = 1e-14
Identities = 62/250 (24%), Positives = 114/250 (44%), Gaps = 50/250 (20%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
++LIE + G+YG V + +L A+K +M I ++++DE
Sbjct: 21 FELIEVVGNGTYGQVYKGRHVKTAQLAAIK----------------IMNINEDEEDEIKL 64
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
+N L KH S N + + + + GKH +
Sbjct: 65 EINM-------LKKH----------SHHRNVATYYGAFIKKLPSSTGKHDQL-------- 99
Query: 138 SYIIMEYCSGGDLYEAIKDDMVPR-KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
+++ME+C G + + +K+ K + + I +IL + ++H + HRDIK +N+L
Sbjct: 100 -WLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVL 158
Query: 197 IAGNWNIKLTDWGL-ATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKVDI 253
+ + +KL D+G+ A DKT RN +G+ +MAPE+ +E +A ++ D+
Sbjct: 159 LTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIAC----DESPEATYDSRSDL 214
Query: 254 WAIGIVMLNI 263
W++GI L +
Sbjct: 215 WSLGITALEM 224
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 80.5 bits (197), Expect = 1e-14
Identities = 62/250 (24%), Positives = 114/250 (44%), Gaps = 50/250 (20%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
++LIE + G+YG V + +L A+K +M I ++++DE
Sbjct: 21 FELIEVVGNGTYGQVYKGRHVKTAQLAAIK----------------IMNINEDEEDEIKL 64
Query: 78 TVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFD 137
+N L KH S N + + + + GKH +
Sbjct: 65 EINM-------LKKH----------SHHRNVATYYGAFIKKLPSSTGKHDQL-------- 99
Query: 138 SYIIMEYCSGGDLYEAIKDDMVPR-KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
+++ME+C G + + +K+ K + + I +IL + ++H + HRDIK +N+L
Sbjct: 100 -WLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVL 158
Query: 197 IAGNWNIKLTDWGL-ATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKVDI 253
+ + +KL D+G+ A DKT RN +G+ +MAPE+ +E +A ++ D+
Sbjct: 159 LTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIAC----DESPEATYDSRSDL 214
Query: 254 WAIGIVMLNI 263
W++GI L +
Sbjct: 215 WSLGITALEM 224
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 80.5 bits (197), Expect = 1e-14
Identities = 51/164 (31%), Positives = 82/164 (49%), Gaps = 21/164 (12%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I +G H+N+ ++ F+ YI+ME C GG+L + I + K V ++
Sbjct: 119 EVKILQALGGHENVVGFHNAFEDKTYIYIVMELCDGGELLDRILANRYTEKDAAV--VVR 176
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDKTSMERN--VGSER 226
Q+L H RG+ HRD+KPEN L ++K TD+GL+ K ++ VGS
Sbjct: 177 QMLKVAAECHLRGLVHRDMKPENFLFKSTEEGSSLKATDFGLSDFIKPGVKFQDIVGSAY 236
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
Y+APE+ + E D+W+IG++ ++ + PF
Sbjct: 237 YVAPEVLKRRSGPES----------DVWSIGVITYILLCGRRPF 270
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 80.5 bits (197), Expect = 1e-14
Identities = 53/184 (28%), Positives = 92/184 (49%), Gaps = 21/184 (11%)
Query: 139 YIIMEYCSGGDLYEAIKDDMVPRKTKNVTN-IINQILDAVEYVHSRGIYHRDIKPENILI 197
Y +ME GG+L+ + + R T++++ Q++ AV Y H+RG++HRD+KPEN+L+
Sbjct: 102 YFVMELAKGGELFSRVTSN---RFTESLSRKYFRQLISAVRYCHARGVFHRDLKPENLLL 158
Query: 198 AGNWNIKLTDWGLATTDKT-----SMERNVGSERYMAPELFESNLDREERTDAYDCAKVD 252
N ++K++D+GL+ + + G+ Y+APEL YD +K D
Sbjct: 159 DENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKK--------GYDGSKAD 210
Query: 253 IWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTID 312
IW+ G+V+ + PF N + +A + + S D ++LR L +
Sbjct: 211 IWSCGVVLFLLNAGYLPFRDPN----IMGLYRKIHKAQYKLPDWTSSDLRKLLRRLLEPN 266
Query: 313 PTNR 316
P R
Sbjct: 267 PELR 270
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 80.5 bits (197), Expect = 1e-14
Identities = 58/211 (27%), Positives = 105/211 (49%), Gaps = 22/211 (10%)
Query: 116 EVDIQTKIGKHKNITEL---YDFFDS-YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNII- 170
E+ I K+ H N+ L Y+ DS +++ME C+GG+L+ + + R ++ ++
Sbjct: 92 EIAIMAKLAGHPNVVNLKAVYEEKDSVHLVMELCAGGELFHKL--EKYGRYSEVRARVLF 149
Query: 171 NQILDAVEYVHSRGIYHRDIKPENILIA---GNWNIKLTDWGLATTDK--TSMERNVGSE 225
++ V++ H GI HRD+KPENIL+A + IKL D+GLAT K + VGS
Sbjct: 150 KHLMQVVKFCHDSGIVHRDLKPENILMATMSSSSPIKLADFGLATYIKPGEKLSGTVGSP 209
Query: 226 RYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAA 285
Y+APE+ ++ D+W+ G+++ ++ PF ++ AA
Sbjct: 210 FYIAPEVLAGGYNQ----------AADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAA 259
Query: 286 NREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ + + ++ ++R L +DP+ R
Sbjct: 260 DLRFSAEPWDNITSYAKDLIRGMLCVDPSQR 290
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 80.1 bits (196), Expect = 1e-14
Identities = 57/176 (32%), Positives = 86/176 (48%), Gaps = 16/176 (9%)
Query: 100 KVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF-----DSYIIMEYCSGGDLYEAI 154
K++ FS V + Y K +H+N+ L D F D Y + E G DL+ +
Sbjct: 53 KIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLL 111
Query: 155 KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTD 214
+ P + + V + QIL ++YVHS G+ HRD+KP NILI N ++K+ D+GLA
Sbjct: 112 QTR--PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQ 169
Query: 215 KTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
M V + Y APE+ + YD +VDIW+ G + ++ K F
Sbjct: 170 DPQMTGYVSTRYYRAPEIMLT-------WQKYD-VEVDIWSAGCIFAEMIEGKPLF 217
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 80.1 bits (196), Expect = 1e-14
Identities = 68/277 (24%), Positives = 128/277 (45%), Gaps = 58/277 (20%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSE---DDKGNDTKDGVMVIGDEKDDE 74
+K + + +G+YG V L D KL A+K + K+E D+K ++K+D
Sbjct: 128 FKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKRE----DEDKNDG 183
Query: 75 TNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITEL-Y 133
NN + K+ ++S++S+ +H NI +L Y
Sbjct: 184 NNNDNDDGLSKRLERTFAERSILSEI------------------------EHPNIVKLFY 219
Query: 134 DFFDS---YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDI 190
F D+ Y++++Y GG+L+ +K+ +T V+ +I A+ ++H++G+ +RD+
Sbjct: 220 SFHDNSKLYLLLQYIPGGELFYHLKEHGTLDET-TVSFYAAEISCALRFLHTKGVVYRDL 278
Query: 191 KPENILIAGNWNIKLTDWGL---ATTDKTSMERN----------VGSERYMAPELFESNL 237
KPEN L+ ++ LTD+GL + D E + +G+ Y APE+
Sbjct: 279 KPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGK- 337
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
AY D +++G ++ +++ K P+T +N
Sbjct: 338 -------AYS-QNCDWYSLGCLLYDMLVGKPPYTGSN 366
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 80.1 bits (196), Expect = 1e-14
Identities = 79/305 (25%), Positives = 128/305 (41%), Gaps = 66/305 (21%)
Query: 21 IEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNTVN 80
+E I +GS+G V D + +K+VA+K I E + DE +D
Sbjct: 39 LEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAE-------------DEIEDIQQEITV 85
Query: 81 SSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDSYI 140
SQ + K+ S + D L +I
Sbjct: 86 LSQCDSPYVTKYYGSYLKDTKL------------------------------------WI 109
Query: 141 IMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGN 200
IMEY GG + ++ P + I+ +IL ++Y+HS HRDIK N+L++ +
Sbjct: 110 IMEYLGGGSALDLLEPG--PLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 167
Query: 201 WNIKLTDWGLA--TTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKVDIWAI 256
+KL D+G+A TD T ++RN VG+ +MAPE+ + + AYD +K DIW++
Sbjct: 168 GEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQS--------AYD-SKADIWSL 217
Query: 257 GIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQV-LRHALTIDPTN 315
GI + + + P + + F N L +S +F + L + PT
Sbjct: 218 GITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTA 277
Query: 316 RNLEK 320
+ L K
Sbjct: 278 KELLK 282
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 80.1 bits (196), Expect = 1e-14
Identities = 59/210 (28%), Positives = 97/210 (46%), Gaps = 20/210 (9%)
Query: 116 EVDIQTKIGKHKNITELYDFFDSY----IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV I + H+NI +L ++ +IME C GG+L++ I + + + ++
Sbjct: 126 EVQIMHHLSGHRNIVDLKGAYEDRHSVNLIMELCEGGELFDRIISKGLYSE-RAAADLCR 184
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDK--TSMERNVGSER 226
Q++ V HS G+ HRD+KPEN L N +K TD+GL+ K + VGS
Sbjct: 185 QMVMVVHSCHSMGVMHRDLKPENFLFLSKDENSPLKATDFGLSVFFKPGDKFKDLVGSAY 244
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ + N E DIW+ G+++ ++ PF N+T
Sbjct: 245 YVAPEVLKRNYGPE----------ADIWSAGVILYILLSGVPPFWGENETGIFDAILQGQ 294
Query: 287 REALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ D + +S ++R L DP +R
Sbjct: 295 LDFSADPWPALSDGAKDLVRKMLKYDPKDR 324
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 80.1 bits (196), Expect = 1e-14
Identities = 59/232 (25%), Positives = 112/232 (47%), Gaps = 23/232 (9%)
Query: 94 KSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGD 149
KS++ K++S+ + E+ I + NI E+ ++ +++ME C+GG+
Sbjct: 109 KSILKRKLISKQDKE---DVKREIQIMQYLSGQPNIVEIKGAYEDRQSIHLVMELCAGGE 165
Query: 150 LYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLT 206
L++ I + II I++ V+ H G+ HRD+KPEN L++ N +K T
Sbjct: 166 LFDRIIAQG-HYSERAAAGIIRSIVNVVQICHFMGVVHRDLKPENFLLSSKEENAMLKAT 224
Query: 207 DWGLAT-TDKTSMERN-VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIV 264
D+GL+ ++ + R+ VGS Y+APE+ + +E +DIW+ G+++ ++
Sbjct: 225 DFGLSVFIEEGKVYRDIVGSAYYVAPEVLRRSYGKE----------IDIWSAGVILYILL 274
Query: 265 FHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
PF N+ + + + + ++S ++R LT DP R
Sbjct: 275 SGVPPFWAENEKGIFDEVIKGEIDFVSEPWPSISESAKDLVRKMLTKDPKRR 326
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 80.1 bits (196), Expect = 1e-14
Identities = 49/166 (29%), Positives = 83/166 (49%), Gaps = 15/166 (9%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV+IQ+ + +H NI LY +F Y+I+EY G+LY+ ++ + + T + +
Sbjct: 67 EVEIQSHL-RHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVAS 125
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNVGSERYMAPE 231
+ A+ Y H + + HRDIKPEN+LI +K+ D+G + G+ Y+ PE
Sbjct: 126 -LARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLPPE 184
Query: 232 LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTD 277
+ ES A VDIW++GI+ ++ PF ++
Sbjct: 185 MVES---------VEHDASVDIWSLGILCYEFLYGVPPFEAREHSE 221
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 80.1 bits (196), Expect = 1e-14
Identities = 46/162 (28%), Positives = 86/162 (52%), Gaps = 17/162 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV+I +++ KH ++ +LY FF Y+++E G+L+ + P +I+
Sbjct: 62 EVEIHSRL-KHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILK 120
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV---GSERYM 228
Q++ + Y+HS I HRDI N+L++ ++K+ D+GLAT K ER++ G+ Y+
Sbjct: 121 QVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYI 180
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
+PE+ RT D+W++G ++ ++ + PF
Sbjct: 181 SPEVV-------SRTS--HGLPADVWSVGCMLYTLLVGRPPF 213
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 79.7 bits (195), Expect = 2e-14
Identities = 74/267 (27%), Positives = 117/267 (43%), Gaps = 52/267 (19%)
Query: 83 QEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS---- 138
+EKK + K L D+++ R N L E +I H I LY F S
Sbjct: 514 REKKTNRVYALKVLSKDEMIKR---NKIKRVLTEQEILAT-SNHPFIVTLYHSFQSEDYL 569
Query: 139 YIIMEYCSGGDLYEAIKDDMVPRKTKNVTN-----IINQILDAVEYVHSRGIYHRDIKPE 193
Y+ MEYC GG+ + A++ RKTK + +++ A+EY+H G +RD+KPE
Sbjct: 570 YLCMEYCMGGEFFRALQT----RKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPE 625
Query: 194 NILIAGNWNIKLTDWGLATTDKTS------------------------MERNVGSERYMA 229
NIL+ + +I L+D+ L+ K S VG+E Y+A
Sbjct: 626 NILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIA 685
Query: 230 PELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREA 289
PE+ N A VD W +GI++ ++F PF + T++ F N E
Sbjct: 686 PEVIRGN---------GHTAAVDWWTLGILIYEMLFGFTPFK-GDNTNETFTNILKN-EV 734
Query: 290 LFDVFSTMSYDFFQVLRHALTIDPTNR 316
F + +S +++ LT + + R
Sbjct: 735 SFPNNNEISRTCKDLIKKLLTKNESKR 761
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 79.7 bits (195), Expect = 2e-14
Identities = 87/315 (27%), Positives = 135/315 (42%), Gaps = 57/315 (18%)
Query: 19 KLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNT 78
K E+ SEG +V AS KK Y+F G V+ K+ ET
Sbjct: 13 KQTEEDSEGKMAHVQPASYVNKKK-----YVFGKTLGAGT-----FGVVRQAKNTETGED 62
Query: 79 VNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALY-EVDIQTKIGKHKNITELYDFFD 137
V ++ K L N V EALY E+DI ++ H NI D+F+
Sbjct: 63 V-------------AVKILIKKALK--GNKVQLEALYDELDILQRL-HHPNIVAFKDWFE 106
Query: 138 S----YIIMEYCSGGDLYEAIKDDMVPRKTK----NVTNIINQILDAVEYVHSRGIYHRD 189
S YII + GG+L+ D + +K K + I+ +IL AV+Y+HS+ I HRD
Sbjct: 107 SKDKFYIITQLAKGGELF-----DRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRD 161
Query: 190 IKPENILIAGNWN---IKLTDWGLA---TTDKTSMERNVGSERYMAPELFESNLDREERT 243
+KPEN+L + + + D+G+A +D+ + + GS Y+APE+ T
Sbjct: 162 LKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVL---------T 212
Query: 244 DAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALF--DVFSTMSYDF 301
DIW+IG++ ++ + F D F + ++S
Sbjct: 213 QDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKA 272
Query: 302 FQVLRHALTIDPTNR 316
Q + AL +DP+ R
Sbjct: 273 KQFILKALNLDPSKR 287
>YDR283c [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1659
Score = 79.7 bits (195), Expect = 2e-14
Identities = 66/260 (25%), Positives = 117/260 (44%), Gaps = 37/260 (14%)
Query: 23 DISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNTVNSS 82
D+SE S SD + L+ IFK+ + D + + G D NSS
Sbjct: 681 DLSESS-------SDFEENDLLDQSSIFKNRTNHDLDNSNWDFISGSGYPDIVFE--NSS 731
Query: 83 QEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDSYIIM 142
++ + L H S S S ++ E+ ++ + K +T + +I M
Sbjct: 732 RDDENEDLDHDTSSTSS---SESQDDTDKESKSIQNVPRRRNFVKPMTAVKKKSTLFIQM 788
Query: 143 EYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWN 202
EYC LY+ I + + ++ + QIL+A+ Y+HS+GI HRD+KP NI I + N
Sbjct: 789 EYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRN 848
Query: 203 IKLTDWGLATTDKTSME-----------------RNVGSERYMAPELFESNLDREERTDA 245
+K+ D+GLA S++ +G+ Y+A E+ + T
Sbjct: 849 VKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDG-------TGH 901
Query: 246 YDCAKVDIWAIGIVMLNIVF 265
Y+ K+D++++GI+ +++
Sbjct: 902 YN-EKIDMYSLGIIFFEMIY 920
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 79.7 bits (195), Expect = 2e-14
Identities = 72/284 (25%), Positives = 122/284 (42%), Gaps = 31/284 (10%)
Query: 66 VIGDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGK 125
V GD D + + V + +KK K + DK N V + + E D ++
Sbjct: 55 VFGDIIGDGSFSKVRRATDKKS--WKEYAIKVLDKKYIVKENKVKYVNI-ERDSMMRLNG 111
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
I+ L+ F Y ++E G+L + IK + V +IL ++EY+H
Sbjct: 112 FPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENC-VRFYAAEILSSIEYMH 170
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLA---------TTDKTSMERN-VGSERYMAPE 231
S GI HRD+KPENIL GN ++K+TD+G A + D T+ + VG+ Y+APE
Sbjct: 171 SCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPE 230
Query: 232 LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALF 291
L + + D+WA V+ ++ PF +N + F +
Sbjct: 231 LLSRQVVSKSS---------DLWAFACVVYQMIVGSPPFHGSNPNN----IFKKIMSLEY 277
Query: 292 DVFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEYTMDD 335
++ + D + H I P++R+ + + + T D+
Sbjct: 278 ELPKLLPPDIVPLFSHLFRIQPSDRSTTQQIKQFPFFATITWDN 321
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 79.7 bits (195), Expect = 2e-14
Identities = 56/176 (31%), Positives = 86/176 (48%), Gaps = 16/176 (9%)
Query: 100 KVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFF-----DSYIIMEYCSGGDLYEAI 154
K++ FS V + Y K +H+NI L D F D Y + E G DL+ +
Sbjct: 50 KIMKPFSTPVLAKRTYRELKLLKHLRHENIISLSDIFISPFEDIYFVTELL-GTDLHRLL 108
Query: 155 KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTD 214
P +T+ + + QIL +++VHS G+ HRD+KP NILI N ++K+ D+GLA
Sbjct: 109 TSR--PLETQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQ 166
Query: 215 KTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
M V + Y APE+ + Y+ +VDIW+ G + ++ K F
Sbjct: 167 DPQMTGYVSTRYYRAPEIMLT-------WQKYN-VEVDIWSAGCIFAEMIEGKPLF 214
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 79.7 bits (195), Expect = 2e-14
Identities = 56/203 (27%), Positives = 97/203 (47%), Gaps = 19/203 (9%)
Query: 125 KHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
K+ NI D + + +++MEY +GG L + + + + + + + L A+E++
Sbjct: 323 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEG--QIAAVCRECLQALEFL 380
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGSERYMAPELFESNL 237
HS + HRDIK +NIL+ + ++KLTD+G T +++ VG+ +MAPE+
Sbjct: 381 HSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRK- 439
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
AY KVDIW++GI+ + ++ + P+ N +A A N +
Sbjct: 440 -------AYG-PKVDIWSLGIMAIEMIEGEPPYLNENPL-RALYLIATNGTPELQNPEKL 490
Query: 298 SYDFFQVLRHALTIDPTNRNLEK 320
S F L L +D R K
Sbjct: 491 SAIFRDFLNRCLDMDVEKRGSAK 513
>At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 575
Score = 79.7 bits (195), Expect = 2e-14
Identities = 51/168 (30%), Positives = 87/168 (51%), Gaps = 24/168 (14%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKT----KNVT 167
E+ I + NI ++ ++ +I+ME C GG+L++ I D +V + K+
Sbjct: 70 EIQIMDHVSGQPNIVQIKGSYEDNNSIHIVMELCGGGELFDKI-DALVKSHSYYSEKDAA 128
Query: 168 NIINQILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDK--TSMERNV 222
I I++AV+ HS + HRD+KPEN L + N +K D+G + K + ER V
Sbjct: 129 GIFRSIVNAVKICHSLDVVHRDLKPENFLFSSKDENAMLKAIDFGCSVYIKEGKTFERVV 188
Query: 223 GSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
GS+ Y+APE+ E + +E +DIW+ G+++ ++ PF
Sbjct: 189 GSKYYIAPEVLEGSYGKE----------IDIWSAGVILYILLSGVPPF 226
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 79.7 bits (195), Expect = 2e-14
Identities = 68/263 (25%), Positives = 114/263 (42%), Gaps = 33/263 (12%)
Query: 96 LISDKVLSR---FSNNVCFEALYEVDIQTKIGKHKNITELYDFF---DSYIIMEYCSGGD 149
L + KVL + N L E DI + + Y F + Y++MEY +GGD
Sbjct: 915 LFAIKVLKKADMIRKNAVESILAERDILINVRNPFVVRFFYSFTCRDNLYLVMEYLNGGD 974
Query: 150 LYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWG 209
LY +++ + + V I +++ A+EY+HS G+ HRD+KP+N+LIA + +IKLTD+G
Sbjct: 975 LYSLLRN-LGCLEEDIVRVYIAEVVLALEYLHSEGVVHRDLKPDNLLIAHDGHIKLTDFG 1033
Query: 210 LATTDKTSMERNVGSERYMAPELF----------ESNLDREERTDAYDC----------- 248
L+ + ++ L E L+R ++ A
Sbjct: 1034 LSKVGLINSTDDLAGPAVSGTSLLDEEESRLAASEEQLERRKKRSAVGTPDYLAPEILLG 1093
Query: 249 ----AKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQV 304
A D W++GI++ ++ PF A + F + V MS + +
Sbjct: 1094 TGHGATADWWSVGIILFELIVGIPPFN-AEHPQQIFDNILNRKIPWPHVPEEMSAEAHDI 1152
Query: 305 LRHALTIDPTNRNLEKVRTEIKR 327
+ LT DP R + E+K+
Sbjct: 1153 IDRFLTEDPHQRLGARGAAEVKQ 1175
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 79.7 bits (195), Expect = 2e-14
Identities = 85/333 (25%), Positives = 129/333 (38%), Gaps = 94/333 (28%)
Query: 16 DRYKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDET 75
DRY E + +G+YG V A+DT+ + VA+K I ++ +G
Sbjct: 9 DRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEG------------------ 50
Query: 76 NNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF 135
VN + ++ +LLK K H +I EL D
Sbjct: 51 ---VNVTALREIKLLKELK-------------------------------HPHIIELIDA 76
Query: 136 F----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIK 191
F + +I+ E+ DL I+D + +V + + IL +EY H + + HRD+K
Sbjct: 77 FPHKENLHIVFEFMET-DLEAVIRDRNLYLSPGDVKSYLQMILKGLEYCHGKWVLHRDMK 135
Query: 192 PENILIAGNWNIKLTDWGLAT---TDKTSMERNVGSERYMAPELFESNLDREERTDAYDC 248
P N+LI N +KL D+GLA + V + Y APEL YD
Sbjct: 136 PNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFG-------AKQYDG 188
Query: 249 AKVDIWAIGIVMLNIVFHKNPFTVAN----QTDKAFCYFAANR----------------- 287
A VD+WA G + ++ + PF N Q K F F +
Sbjct: 189 A-VDVWAAGCIFAELLL-RRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVEYQ 246
Query: 288 ----EALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+L + T+S D +L T DP +R
Sbjct: 247 FVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSR 279
>7300288 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 630
Score = 79.7 bits (195), Expect = 2e-14
Identities = 53/189 (28%), Positives = 91/189 (48%), Gaps = 25/189 (13%)
Query: 93 QKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDSYIIMEYCSGGDLYE 152
Q L K+L++ NVC ALY+ + + K + E D + I+ Y + LY
Sbjct: 378 QGYLNETKLLAKLQGNVCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTNLPLY- 436
Query: 153 AIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT 212
++ NI+ Q+L AV Y+H G+ H D+KP N L+ +KL D+G+A+
Sbjct: 437 ------------SLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSG-RLKLIDFGIAS 483
Query: 213 ---TDKTSMER--NVGSERYMAPELF------ESNLDREERTDAYDCAKVDIWAIGIVML 261
D TS+ + G+ Y++PE S + R ++ K D+W++G ++
Sbjct: 484 NIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILY 543
Query: 262 NIVFHKNPF 270
+++ K PF
Sbjct: 544 LLLYQKTPF 552
>YOR267c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 759
Score = 79.3 bits (194), Expect = 2e-14
Identities = 56/195 (28%), Positives = 90/195 (45%), Gaps = 31/195 (15%)
Query: 126 HKNITELYDFFDS------YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEY 179
H N+ E D F Y +MEYC D + + + R N + Q+ + V+Y
Sbjct: 274 HPNVIETVDVFSDSKQNKYYEVMEYCPI-DFFAVVMTGKMSRGEINCC--LKQLTEGVKY 330
Query: 180 VHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN-------VGSERYMAPEL 232
+HS G+ HRD+K +N ++ +KL D+G A + E VGS+ Y+APE+
Sbjct: 331 LHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEV 390
Query: 233 FESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFD 292
S T +YD VDIW+IGI+ +V + P+ +D F L+
Sbjct: 391 ITS-------TKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNF--------RLYC 435
Query: 293 VFSTMSYDFFQVLRH 307
+ + +D+ + RH
Sbjct: 436 MPDDIEHDYVESARH 450
>SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 461
Score = 79.3 bits (194), Expect = 2e-14
Identities = 67/214 (31%), Positives = 99/214 (45%), Gaps = 23/214 (10%)
Query: 140 IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG 199
++ EYC GDL++ I++ ++ + K + QIL AV Y+ S+ I HRD+KPENILI
Sbjct: 209 LVQEYCPQGDLFKQIEEKVLTLEDKCC--YLKQILQAVAYLQSQRIAHRDLKPENILIGR 266
Query: 200 NWNIKLTDWGLATT-----DKTS---MERNVGSERYMAPELFESNLDREERTDAYDCAKV 251
+ +KLTD+G + D S + VGS Y+APE F N Y
Sbjct: 267 DGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGSLAYLAPEAFHEN--------EYCGLLA 318
Query: 252 DIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTI 311
D W+ GI++ + PF + +TD Y++ L D S D +
Sbjct: 319 DRWSCGILLKVLFTGYFPFKTSVKTD---LYYSKYMSILTDTCGISSTDESSFQTEVIKQ 375
Query: 312 DPTNRNLEKVRTEIKR--LSEYTMDDEYYNSLDS 343
PT + L + K+ LS D + SLDS
Sbjct: 376 IPTLQPLRYIPEGAKKIILSLLNPDSQNRPSLDS 409
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 79.3 bits (194), Expect = 2e-14
Identities = 63/210 (30%), Positives = 105/210 (50%), Gaps = 36/210 (17%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
KH NI L+D Y+I + +GG+L+E D+V R+ + ++ I QIL+AV
Sbjct: 68 KHPNIVRLHDSISEEGHHYLIFDLVTGGELFE----DIVAREYYSEADASHCIQQILEAV 123
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATT---DKTSMERNVGSERYMAPE 231
+ H G+ HRD+KPEN+L+A +KL D+GLA ++ + G+ Y++PE
Sbjct: 124 LHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPE 183
Query: 232 LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN-----QTDKAFCYFAAN 286
+ R D Y VD+WA G+++ ++ PF + Q KA Y +
Sbjct: 184 VL--------RKDPYG-KPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 234
Query: 287 REALFDVFSTMSYDFFQVLRHALTIDPTNR 316
E + T++ + ++ LTI+P+ R
Sbjct: 235 PE-----WDTVTPEAKDLINKMLTINPSKR 259
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 79.3 bits (194), Expect = 2e-14
Identities = 54/237 (22%), Positives = 115/237 (47%), Gaps = 19/237 (8%)
Query: 112 EALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKN-V 166
E L+E+ + + L++ +++ +I+EY +GG+++ ++ ++N V
Sbjct: 76 EILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDV 135
Query: 167 TNIINQILDAVEYVHSRGIYHRDIKPENILIAGNW---NIKLTDWGLATT--DKTSMERN 221
+I QIL+ V Y+H I H D+KP+NIL++ + +IK+ D+G++ +
Sbjct: 136 IRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREI 195
Query: 222 VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFC 281
+G+ Y+APE+ L+ + T A D+W IGI+ ++ H +PF + +
Sbjct: 196 MGTPEYLAPEI----LNYDPITTA-----TDMWNIGIIAYMLLTHTSPFVGEDNQETYLN 246
Query: 282 YFAANREALFDVFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEYTMDDEYY 338
N + + FS++S ++ L +P R ++ L ++ ++ ++
Sbjct: 247 ISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFH 303
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 79.3 bits (194), Expect = 2e-14
Identities = 63/210 (30%), Positives = 104/210 (49%), Gaps = 36/210 (17%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRK---TKNVTNIINQILDAV 177
KH NI L+D Y++ + +GG+L+E D+V R+ + ++ I QIL++V
Sbjct: 69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFE----DIVAREYYSEADASHCIQQILESV 124
Query: 178 EYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATT---DKTSMERNVGSERYMAPE 231
+ H GI HRD+KPEN+L+A +KL D+GLA D+ + G+ Y++PE
Sbjct: 125 NHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE 184
Query: 232 LFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN-----QTDKAFCYFAAN 286
+ R D Y VD+WA G+++ ++ PF + Q KA Y +
Sbjct: 185 VL--------RKDPYG-KPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 235
Query: 287 REALFDVFSTMSYDFFQVLRHALTIDPTNR 316
E + T++ + ++ LTI+P R
Sbjct: 236 PE-----WDTVTPEAKDLINKMLTINPAKR 260
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 79.3 bits (194), Expect = 2e-14
Identities = 60/212 (28%), Positives = 104/212 (48%), Gaps = 24/212 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
E+ I + +NI E+ ++ +++ME C G +L++ I K +I
Sbjct: 150 EIQIMQYLSGQENIVEIKGAYEDRQSIHLVMELCGGSELFDRIIAQG-HYSEKAAAGVIR 208
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLAT-TDKTSMERN-VGSER 226
+L+ V+ H G+ HRD+KPEN L+A N +K TD+GL+ ++ + R+ VGS
Sbjct: 209 SVLNVVQICHFMGVIHRDLKPENFLLASTDENAMLKATDFGLSVFIEEGKVYRDIVGSAY 268
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ + +E +DIW+ GI++ ++ PF ++T+K
Sbjct: 269 YVAPEVLRRSYGKE----------IDIWSAGIILYILLCGVPPFW--SETEKGIFNEIIK 316
Query: 287 REALFD--VFSTMSYDFFQVLRHALTIDPTNR 316
E FD + ++S ++R LT DP R
Sbjct: 317 GEIDFDSQPWPSISESAKDLVRKLLTKDPKQR 348
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 79.3 bits (194), Expect = 2e-14
Identities = 62/205 (30%), Positives = 108/205 (52%), Gaps = 31/205 (15%)
Query: 86 KQRLLKHQKSLISD-KVLSRFSNN----VCFEALYEVDIQTKIGKHKNITELYDFFDS-- 138
K+ L ++SL ++ +VL RFS N C T++ H NI +L + ++
Sbjct: 65 KKALKGKEESLENEIRVLRRFSANHFDGKCLNG-------TRL-THPNIVQLLETYEDKS 116
Query: 139 --YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENIL 196
Y++ME +GG+L++ I + + K+ +++I QIL+AV+Y+H +G+ HRD+KPEN+L
Sbjct: 117 KVYLVMELVTGGELFDRIVEKGSYTE-KDASHLIRQILEAVDYMHEQGVVHRDLKPENLL 175
Query: 197 IAG---NWNIKLTDWGLA-TTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVD 252
+ I ++D+GL+ D M G+ Y+APE+ Y A VD
Sbjct: 176 YYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQK--------PYGKA-VD 226
Query: 253 IWAIGIVMLNIVFHKNPFTVANQTD 277
+W+IG++ ++ PF N +
Sbjct: 227 VWSIGVISYILLCGYPPFYDENDAN 251
>Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 544
Score = 79.0 bits (193), Expect = 3e-14
Identities = 56/203 (27%), Positives = 97/203 (47%), Gaps = 19/203 (9%)
Query: 125 KHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
K+ NI D + + +++MEY +GG L + + + + + + + L A++++
Sbjct: 321 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEG--QIAAVCRECLQALDFL 378
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGSERYMAPELFESNL 237
HS + HRDIK +NIL+ + ++KLTD+G T +++ VG+ +MAPE+
Sbjct: 379 HSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRK- 437
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
AY KVDIW++GI+ + +V + P+ N +A A N +
Sbjct: 438 -------AYG-PKVDIWSLGIMAIEMVEGEPPYLNENPL-RALYLIATNGTPELQNPERL 488
Query: 298 SYDFFQVLRHALTIDPTNRNLEK 320
S F L L +D R K
Sbjct: 489 SAVFRDFLNRCLEMDVDRRGSAK 511
>Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neurofibromin
Length = 445
Score = 79.0 bits (193), Expect = 3e-14
Identities = 55/172 (31%), Positives = 80/172 (45%), Gaps = 26/172 (15%)
Query: 125 KHKNITELYDFFDS------YIIMEYCSGGDLYEAIKDDMVPRKTKN---VTNIINQILD 175
KH NI YD YI+MEYC GGDL I R+ + V ++ Q+
Sbjct: 63 KHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTL 122
Query: 176 AVEYVHSRG-----IYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGSERY 227
A++ H R + HRD+KP N+ + G N+KL D+GLA D + + VG+ Y
Sbjct: 123 ALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTPYY 182
Query: 228 MAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKA 279
M+PE E K DIW++G ++ + PFT +Q + A
Sbjct: 183 MSPEQMNRMSYNE---------KSDIWSLGCLLYELCALMPPFTAFSQKELA 225
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 79.0 bits (193), Expect = 3e-14
Identities = 65/226 (28%), Positives = 103/226 (44%), Gaps = 28/226 (12%)
Query: 66 VIGDEKDDETNNTVNSSQEKKQRLLKHQKSLISDKVLSRFSNNVCFEALY---------E 116
VIGD ++ S K+ L K+ K + + + EA+ E
Sbjct: 203 VIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGSTEHLIENE 262
Query: 117 VDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQ 172
V I ++ KH NI L + ++ +++ME GGDL++AI + + N
Sbjct: 263 VSILRRV-KHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYN- 320
Query: 173 ILDAVEYVHSRGIYHRDIKPENILIA----GNWNIKLTDWGLATTDKTSMERNVGSERYM 228
+ +A+ Y+H I HRDIKPEN+L+ G ++KL D+GLAT + + G+ Y+
Sbjct: 321 LANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYV 380
Query: 229 APELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVAN 274
APE+ Y KVDIWA G++ ++ PF N
Sbjct: 381 APEIIAET--------GYG-LKVDIWAAGVITYILLCGFPPFRSEN 417
>CE27899 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 318
Score = 79.0 bits (193), Expect = 3e-14
Identities = 74/324 (22%), Positives = 145/324 (43%), Gaps = 74/324 (22%)
Query: 18 YKLIEDISEGSYGYVSLASDTQLKKLVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNN 77
Y ++ +SEG+YG VSL E K D K V I
Sbjct: 21 YNVVRFLSEGTYGQVSLY-----------------ESSKNPDVKIAVKQI---------- 53
Query: 78 TVNSSQEKKQRLLKHQKSLIS-DKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDF- 135
S+ + +R ++H K+ + K LS KIG H+N+ + +
Sbjct: 54 ---STAGQSERFVEHIKTEFAIHKGLS------------------KIGGHRNVISMMEMR 92
Query: 136 --FDSYIIM-EYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKP 192
D Y ++ EY GGDL++ ++ + + ++N Q++ ++++H I HRDIK
Sbjct: 93 KGSDCYTLLKEYADGGDLFKKLETEG-EQYSENAQCFFKQLISGLKFIHEHEIVHRDIKL 151
Query: 193 ENILIAGNWN------IKLTDWGLATT-----DKTSMERNVGSERYMAPELFESNLDREE 241
EN+L+ + + +K+ D+GLAT ++ + N GS Y APE++ R
Sbjct: 152 ENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAAPEVYSKQGHRGP 211
Query: 242 RTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDF 301
T D+W+ G++++ ++ P+ A++ D + + + ++++ +S
Sbjct: 212 PT--------DVWSSGVILMAMLTAGLPWDCAHRKDVDYAAWIDKKFRTDNLWNDISDRA 263
Query: 302 FQVLRHALTIDPTNR-NLEKVRTE 324
+LR L ++ + R ++E++ +
Sbjct: 264 LALLRKILCVNVSERVSIEQIEAD 287
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 79.0 bits (193), Expect = 3e-14
Identities = 61/254 (24%), Positives = 115/254 (45%), Gaps = 23/254 (9%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCS 146
K Q K + F+A EVDI + H+ + +L+D ++ Y+I E C
Sbjct: 470 KCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCE 529
Query: 147 GGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIA----GNWN 202
GG+L + + + K V I+ +L+AV+Y+HS+ + HRD+ NIL A +
Sbjct: 530 GGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSS 589
Query: 203 IKLTDWGLATTDKTS---MERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIV 259
+++ D+G A + + + +++APE+ R YD D+W++G++
Sbjct: 590 LRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVL--------RKQGYD-RSCDVWSLGVL 640
Query: 260 MLNIVFHKNPFTVA-NQTDKAFCYFAANRE--ALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ ++ PF + N T + + V+ T+S + ++R L +DP R
Sbjct: 641 LHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRR 700
Query: 317 NLEKVRTEIKRLSE 330
K + K + +
Sbjct: 701 VTAKQALQHKWIGQ 714
Score = 73.6 bits (179), Expect = 1e-12
Identities = 47/159 (29%), Positives = 90/159 (56%), Gaps = 17/159 (10%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H I +L+ F + Y+I+++ GGDL+ + +++ + +V + ++ A+E++H
Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED-DVKFYLAELTLALEHLH 221
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN---VGSERYMAPELFESNLD 238
S GI +RD+KPENIL+ + +IK+TD+GL+ S ++ G+ YMAPE+ ++
Sbjct: 222 SLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEV----IN 277
Query: 239 REERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTD 277
R + A D W++G++M ++ PF ++ D
Sbjct: 278 RRGHSMA-----ADFWSLGVLMFEMLTGHLPFQGRDRND 311
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 79.0 bits (193), Expect = 3e-14
Identities = 61/254 (24%), Positives = 115/254 (45%), Gaps = 23/254 (9%)
Query: 91 KHQKSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCS 146
K Q K + F+A EVDI + H+ + +L+D ++ Y+I E C
Sbjct: 413 KCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCE 472
Query: 147 GGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIA----GNWN 202
GG+L + + + K V I+ +L+AV+Y+HS+ + HRD+ NIL A +
Sbjct: 473 GGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSS 532
Query: 203 IKLTDWGLATTDKTS---MERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIV 259
+++ D+G A + + + +++APE+ R YD D+W++G++
Sbjct: 533 LRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVL--------RKQGYD-RSCDVWSLGVL 583
Query: 260 MLNIVFHKNPFTVA-NQTDKAFCYFAANRE--ALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ ++ PF + N T + + V+ T+S + ++R L +DP R
Sbjct: 584 LHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRR 643
Query: 317 NLEKVRTEIKRLSE 330
K + K + +
Sbjct: 644 VTAKQALQHKWIGQ 657
Score = 73.6 bits (179), Expect = 1e-12
Identities = 47/159 (29%), Positives = 90/159 (56%), Gaps = 17/159 (10%)
Query: 126 HKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H I +L+ F + Y+I+++ GGDL+ + +++ + +V + ++ A+E++H
Sbjct: 106 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED-DVKFYLAELTLALEHLH 164
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERN---VGSERYMAPELFESNLD 238
S GI +RD+KPENIL+ + +IK+TD+GL+ S ++ G+ YMAPE+ ++
Sbjct: 165 SLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEV----IN 220
Query: 239 REERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTD 277
R + A D W++G++M ++ PF ++ D
Sbjct: 221 RRGHSMA-----ADFWSLGVLMFEMLTGHLPFQGRDRND 254
>At4g26890 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 444
Score = 79.0 bits (193), Expect = 3e-14
Identities = 63/211 (29%), Positives = 101/211 (47%), Gaps = 31/211 (14%)
Query: 140 IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG 199
I+MEY SGG+L++ IK+ + + QIL+ + Y+H RGI H D+K N+L+
Sbjct: 77 ILMEYVSGGNLHDLIKNSGGKLPEPEIRSYTRQILNGLVYLHERGIVHCDLKSHNVLVEE 136
Query: 200 NWNIKLTDWGLA-TTDKTSMERNVGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGI 258
N +K+ D G A + DK+ G+ +MAPE+ E+R A D+WA+G
Sbjct: 137 NGVLKIADMGCAKSVDKSEFS---GTPAFMAPEVARG---EEQRFPA------DVWALGC 184
Query: 259 VMLNIVFHKNPFTVANQTDKAF--CYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
M+ ++ +P+ N A F+ A+ S + DF L++ L D
Sbjct: 185 TMIEMMTGSSPWPELNDVVAAMYKIGFSGESPAIPAWISDKAKDF---LKNCLKED---- 237
Query: 317 NLEKVRTEIKRLSEYTMDDEYYNSLDSDEES 347
+K R ++ L ++ LD DEES
Sbjct: 238 --QKQRWTVEELLKHPF-------LDDDEES 259
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 79.0 bits (193), Expect = 3e-14
Identities = 51/164 (31%), Positives = 79/164 (48%), Gaps = 19/164 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV + + HK + + YD + YI+ME C GG+L + I + I+
Sbjct: 194 EVKLLKSLSGHKYLIKYYDACEDANNVYIVMELCDGGELLDRILARGGKYPEDDAKAIVV 253
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDKTSMERN--VGSER 226
QIL V + H +G+ HRD+KPEN L + ++KL D+GL+ + N VGS
Sbjct: 254 QILTVVSFCHLQGVVHRDLKPENFLFTSSREDSDLKLIDFGLSDFIRPDERLNDIVGSAY 313
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
Y+APE+ + E DIW+IG++ ++ PF
Sbjct: 314 YVAPEVLHRSYSLE----------ADIWSIGVITYILLCGSRPF 347
>At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 567
Score = 79.0 bits (193), Expect = 3e-14
Identities = 58/212 (27%), Positives = 95/212 (44%), Gaps = 24/212 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAI--KDDMVPRKTKNVTNI 169
EV I + + +H N+ +L ++ +++ME C GG+L++ I + R V
Sbjct: 107 EVTIMSTLPEHPNVVKLKATYEDNENVHLVMELCEGGELFDRIVARGHYTERAAATVART 166
Query: 170 INQILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLTDWGLATTDKTS--MERNVGS 224
I ++ V H G+ HRD+KPEN L A N +K D+GL+ K VGS
Sbjct: 167 IAEV---VRMCHVNGVMHRDLKPENFLFANKKENSALKAIDFGLSVLFKPGERFTEIVGS 223
Query: 225 ERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFA 284
YMAPE+ + N E VD+W+ G+++ ++ PF + A
Sbjct: 224 PYYMAPEVLKRNYGPE----------VDVWSAGVILYILLCGVPPFWAETEQGVALAILR 273
Query: 285 ANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ D +S +S +++ L D T R
Sbjct: 274 GVLDFKRDPWSQISESAKSLVKQMLEPDSTKR 305
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 78.6 bits (192), Expect = 4e-14
Identities = 57/216 (26%), Positives = 102/216 (46%), Gaps = 29/216 (13%)
Query: 126 HKNITELYDFFDSY----IIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYVH 181
H NI L + + I++E+ SGG+ Y+ I+ K + + Q++ V Y+H
Sbjct: 109 HPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKR-RLKESSACRLFAQLISGVNYMH 167
Query: 182 SRGIYHRDIKPENILIAGNWNIKLTDWGLAT---TDKTSMERNVGSERYMAPELFESNLD 238
+G+ HRD+K EN+L+ + N+ +TD+G D M+ + GS Y APEL S
Sbjct: 168 YKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVS--- 224
Query: 239 REERTDAYDCAKVDIWAIGIVMLNIVF--------HKNPFTVANQTDKAFCYFAANREAL 290
T AY+ K D+W+ G+++ ++ H+NP + + + Y
Sbjct: 225 ----TKAYEARKADVWSCGVILYAMLAGYLPWDDDHENP--TGDDIARLYKYITQTPLKF 278
Query: 291 FDVFSTMSYDFFQVLRHALTIDPTNR-NLEKVRTEI 325
+ + + D +LR L +P R NL+ ++ +
Sbjct: 279 PEYITPIPRD---LLRRILVPNPRRRINLQTIKRHV 311
>YKL168c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 734
Score = 78.6 bits (192), Expect = 4e-14
Identities = 68/242 (28%), Positives = 114/242 (47%), Gaps = 30/242 (12%)
Query: 99 DKVLSRFSNNVCFEAL--YEVDIQTKIGKHK--NITELYDFFD---SYI-IMEYCSGGDL 150
D L +F + E + + + K GK NI ++D + S+I +ME+C GDL
Sbjct: 472 DSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSSSFIEVMEFCPAGDL 531
Query: 151 YEAI--KDDMVPR-KTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTD 207
Y + K + R + Q+L V+++H GI H D+KPENIL + +K+ D
Sbjct: 532 YGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICD 591
Query: 208 WGLATTDKTSMERNV-------GSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVM 260
+G ++ +T+ ER V GSE Y+APE F + YD +D W+ G+V
Sbjct: 592 FGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDG-------EYYDPRLIDCWSCGVVY 644
Query: 261 LNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNRNLEK 320
+ ++ + VA++ +K Y E ++ + F+ L+H + TNR +
Sbjct: 645 ITMILGHYLWKVASR-EKDMSY----DEFYKEMQRKNQFRVFEELKHVNSELATNRKIAL 699
Query: 321 VR 322
R
Sbjct: 700 YR 701
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 78.6 bits (192), Expect = 4e-14
Identities = 55/203 (27%), Positives = 97/203 (47%), Gaps = 18/203 (8%)
Query: 125 KHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
K+ NI D + + +++MEY +GG L + + + + + + + + L A+E++
Sbjct: 302 KNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETACMDEAQ-IAAVCRECLQALEFL 360
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGSERYMAPELFESNL 237
H+ + HRDIK +N+L+ ++KLTD+G T +++ VG+ +MAPE+
Sbjct: 361 HANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRK- 419
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
AY KVDIW++GI+ + +V + P+ N +A A N +
Sbjct: 420 -------AYG-PKVDIWSLGIMAIEMVEGEPPYLNENPL-RALYLIATNGTPELQNPEKL 470
Query: 298 SYDFFQVLRHALTIDPTNRNLEK 320
S F L L +D R K
Sbjct: 471 SPIFRDFLNRCLEMDVEKRGSAK 493
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 78.6 bits (192), Expect = 4e-14
Identities = 70/247 (28%), Positives = 109/247 (43%), Gaps = 16/247 (6%)
Query: 109 VCFEALYEVDIQTKIGKHKNITELYDFFDS---YIIMEYCSGGDL-YEAIKDDMVPRKTK 164
V + E+ + +K+ + Y F D Y++ + GGDL Y +
Sbjct: 69 VAANVIRELTLLSKMSHPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRA 128
Query: 165 NVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLAT--TDKTSMERNV 222
+ + +I AVEY+H I HRDIKPENIL+ + LTD LAT D
Sbjct: 129 KL--YLCEICLAVEYLHEMKIVHRDIKPENILLDEQGHAHLTDLNLATQLEDDQLATSYS 186
Query: 223 GSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCY 282
G+ YMAPE++ + L+ E D YD ++VD WA+G+ ++ + PF +++T Y
Sbjct: 187 GTRPYMAPEIYATYLEIE---DGYD-SRVDWWALGVCFYEMLRGRTPFEFSSRTKPEEAY 242
Query: 283 FAANREALFDVFSTMSYDFFQVLRHALTIDPTNRNLEKVRTEIKRLSEYTMDDEYYNSLD 342
A RE+ + D Q + L D R V E + YT ++ + +
Sbjct: 243 -VAFRESSIPYPAHWPTDLIQFINSMLKFDKEKR---LVGLEAIKKHSYTERIDFKSVFE 298
Query: 343 SDEESVF 349
VF
Sbjct: 299 KKPSPVF 305
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 78.6 bits (192), Expect = 4e-14
Identities = 52/180 (28%), Positives = 87/180 (47%), Gaps = 19/180 (10%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIIN 171
EV + + H+++ + YD ++ +++ME C GG+L + I + I+
Sbjct: 194 EVKLLKALSGHRHMVKFYDVYEDADNVFVVMELCEGGELLDRILARGGRYPEVDAKRILV 253
Query: 172 QILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATTDKTSMERN--VGSER 226
QIL A + H +G+ HRD+KPEN L +K+ D+GL+ + N VGS
Sbjct: 254 QILSATAFFHLQGVVHRDLKPENFLFTSRNEDAILKVIDFGLSDFIRYDQRLNDVVGSAY 313
Query: 227 YMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAAN 286
Y+APE+ L R T+A D+W+IG++ ++ PF ++ C AN
Sbjct: 314 YVAPEV----LHRSYSTEA------DMWSIGVISYILLCGSRPFYGRTESAIFRCVLRAN 363
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 78.6 bits (192), Expect = 4e-14
Identities = 57/232 (24%), Positives = 109/232 (46%), Gaps = 23/232 (9%)
Query: 94 KSLISDKVLSRFSNNVCFEALYEVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGD 149
KS++ K++S + E+ I + N+ E+ ++ +++ME C+GG+
Sbjct: 98 KSILKRKLISELGRE---DVKTEIQIMQHLSGQPNVVEIKGSYEDRHSVHLVMELCAGGE 154
Query: 150 LYEAIKDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAG---NWNIKLT 206
L++ I + I I+D V+ H G+ HRD+KPEN L + N +K+T
Sbjct: 155 LFDRIIAQG-HYSERAAAGTIKSIVDVVQICHLNGVIHRDLKPENFLFSSKEENAMLKVT 213
Query: 207 DWGL-ATTDKTSMERN-VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIV 264
D+GL A ++ + ++ VGS Y+APE+ + +E +DIW+ G+++ ++
Sbjct: 214 DFGLSAFIEEGKIYKDVVGSPYYVAPEVLRQSYGKE----------IDIWSAGVILYILL 263
Query: 265 FHKNPFTVANQTDKAFCYFAANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
PF N+ + + + + ++S ++ LT DP R
Sbjct: 264 CGVPPFWADNEEGVFVEILKCKIDFVREPWPSISDSAKDLVEKMLTEDPKRR 315
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 78.6 bits (192), Expect = 4e-14
Identities = 52/199 (26%), Positives = 96/199 (48%), Gaps = 19/199 (9%)
Query: 125 KHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVTNIINQILDAVEYV 180
KH N+ D + + +++MEY GG L + + + + + + ++L A+E++
Sbjct: 483 KHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEG--QIAAVCREVLQALEFL 540
Query: 181 HSRGIYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGSERYMAPELFESNL 237
H+ + HRDIK +NIL+ + ++KLTD+G + +++ VG+ +MAPE+
Sbjct: 541 HANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVV---- 596
Query: 238 DREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFSTM 297
T KVD+W++GI+ + +V + P+ N KA A N + +
Sbjct: 597 -----TRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPL-KALYLIATNGKPEIKEKDKL 650
Query: 298 SYDFFQVLRHALTIDPTNR 316
S F L L ++ R
Sbjct: 651 SSAFQDFLDQCLEVEVDRR 669
>Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 681
Score = 78.2 bits (191), Expect = 5e-14
Identities = 45/166 (27%), Positives = 89/166 (53%), Gaps = 18/166 (10%)
Query: 112 EALYEVDIQTKIGKHKNITELYDFF----DSYIIMEYCSGGDLYEAIKDDMVPRKTKNVT 167
E L+ + + +H N+ E+Y + + +++ME+ GG L + + V + +
Sbjct: 447 ELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQ--VRLNEEQIA 504
Query: 168 NIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLA---TTDKTSMERNVGS 224
+ +L A+ Y+H++G+ HRDIK ++IL+ + +KL+D+G + D + VG+
Sbjct: 505 TVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGT 564
Query: 225 ERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
+MAPE+ +L E VDIW++GI+++ +V + P+
Sbjct: 565 PYWMAPEVISRSLYATE---------VDIWSLGIMVIEMVDGEPPY 601
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 78.2 bits (191), Expect = 5e-14
Identities = 62/216 (28%), Positives = 102/216 (46%), Gaps = 31/216 (14%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAIKDDMVPRKTKNVTN--- 168
EV I ++G H NI +L++FF+ YI +E C+ L E K + K VT
Sbjct: 86 EVQIHRELG-HINIVKLFNFFEDNLNVYITLELCARRSLMELHK------RRKAVTEPEA 138
Query: 169 --IINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTSMERNV--GS 224
+QI+D V Y+H I HRD+K N+ + + +K+ D+GLATT + G+
Sbjct: 139 RYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTVNGDERKKTLCGT 198
Query: 225 ERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFA 284
Y+APE+ A +VDIWA+G ++ ++F + PF + + ++
Sbjct: 199 PNYIAPEVLNK---------AGHSFEVDIWAVGCILYILLFGQPPFESKSLEET----YS 245
Query: 285 ANREALFDVFSTMSYDFFQVLRHALTIDPTNRNLEK 320
R + + S + ++R L +PT R K
Sbjct: 246 RIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAK 281
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 78.2 bits (191), Expect = 5e-14
Identities = 58/212 (27%), Positives = 96/212 (44%), Gaps = 24/212 (11%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAI--KDDMVPRKTKNVTNI 169
EV+I + +H N+ L + ++ +++ME C GG+L++ I + R VT
Sbjct: 111 EVEIMRHMPEHPNVVTLKETYEDEHAVHLVMELCEGGELFDRIVARGHYTERAAAAVTKT 170
Query: 170 INQILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATTDKTSMERN--VGS 224
I ++ V+ H G+ HRD+KPEN L +K D+GL+ K N VGS
Sbjct: 171 I---MEVVQVCHKHGVMHRDLKPENFLFGNKKETAPLKAIDFGLSVFFKPGERFNEIVGS 227
Query: 225 ERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFA 284
YMAPE+ + N E VDIW+ G+++ ++ PF + A
Sbjct: 228 PYYMAPEVLKRNYGPE----------VDIWSAGVILYILLCGVPPFWAETEQGVAQAIIR 277
Query: 285 ANREALFDVFSTMSYDFFQVLRHALTIDPTNR 316
+ + D + +S + ++R L D R
Sbjct: 278 SVLDFRRDPWPKVSENAKDLIRKMLDPDQKRR 309
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 78.2 bits (191), Expect = 5e-14
Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 116 EVDIQTKIGKHKNITELYDFFDS----YIIMEYCSGGDLYEAI---KDDMVPRKTKNVTN 168
EV I + H+N+ Y+ F+ YI+ME C GG+L + I KD + V
Sbjct: 156 EVKILQALTGHENVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERDAAV-- 213
Query: 169 IINQILDAVEYVHSRGIYHRDIKPENILIAGNWN---IKLTDWGLATTDKTSMERN--VG 223
++ Q+L H RG+ HRD+KPEN L +K TD+GL+ K + + VG
Sbjct: 214 VVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFIKPGKKFHDIVG 273
Query: 224 SERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPF 270
S Y+APE+ + E D+W+IG++ ++ + PF
Sbjct: 274 SAYYVAPEVLKRRSGPES----------DVWSIGVISYILLCGRRPF 310
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 77.8 bits (190), Expect = 7e-14
Identities = 54/207 (26%), Positives = 100/207 (48%), Gaps = 24/207 (11%)
Query: 125 KHKNITELYDFFDS----YIIMEYCSGGDLYEAI--KDDMVPRKTKNVTNIINQILDAVE 178
+H N+ +L D + ++++EY GG+L++ + K + T + QIL +E
Sbjct: 66 EHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDT---AKFLWQILCGLE 122
Query: 179 YVHSRGIYHRDIKPENILIAGNWNIKLTDWGLATTDKTS--MERNVGSERYMAPELFESN 236
Y H I HRD+KPEN+ + + +IK+ ++G+A+ + ++ + GS Y +PE+
Sbjct: 123 YCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKLLQTSCGSPHYASPEIIMGR 182
Query: 237 LDREERTDAYDCAKVDIWAIGIVMLNIVFHKNPFTVANQTDKAFCYFAANREALFDVFST 296
+YD DIW+ GI+ ++ K PF D + F++ S
Sbjct: 183 --------SYDGCASDIWSCGIIFFALLTGKLPF----DDDNIRSLLLKVCQGQFEMPSN 230
Query: 297 MSYDFFQVLRHALTIDPTNR-NLEKVR 322
+S +L L +D + R +E++R
Sbjct: 231 ISPQAQHLLYRMLDVDSSTRITMEQIR 257
>7300098 [T] KOG4250 TANK binding protein kinase TBK1
Length = 741
Score = 77.8 bits (190), Expect = 7e-14
Identities = 53/151 (35%), Positives = 86/151 (56%), Gaps = 25/151 (16%)
Query: 140 IIMEYCSGGDLYEAIKDDMVPRKTKNVTNI-INQILDAVE----YVHSR-GIYHRDIKPE 193
I++EYC+GGD+ + ++ P +T + QIL A+ ++HS+ GI HRD+KP+
Sbjct: 132 IVLEYCNGGDVRKRLQS---PENANGLTEFEVRQILGALRKALHFLHSQCGICHRDLKPD 188
Query: 194 NILIA----GNWNIKLTDWGLA--TTDKTSMERNVGSERYMAPELFESNLDREERTDAYD 247
NI+I G KLTD+GLA T D+T ++ VG+ Y APE+ E + +
Sbjct: 189 NIVIQRGVDGKKIYKLTDFGLARGTPDQTMVQSVVGTRHYYAPEVVE---------NGFY 239
Query: 248 CAKVDIWAIGIVMLNIVFHKNPFTVANQTDK 278
+ VD+W+ G++ +V + PF + +QT K
Sbjct: 240 NSTVDLWSFGVIAYELVTGELPF-IPHQTLK 269
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 77.8 bits (190), Expect = 7e-14
Identities = 67/253 (26%), Positives = 118/253 (46%), Gaps = 31/253 (12%)
Query: 43 LVAVKYIFKSEDDKGNDTKDGVMVIGDEKDDETNNTVNSSQEK----------KQRLLKH 92
L +K + + + NDT E D+E + S +K + L+ +
Sbjct: 654 LGTIKQLREKPSSQRNDTSGRSSTKSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVAY 713
Query: 93 QKSLISDKVLSRFS--NNVCFEALY-EVDIQTKIGKHKNITELYDFFDS----YIIMEYC 145
+ ++ K++ + E +Y E ++ K + I +LY + + Y +ME C
Sbjct: 714 NQQALALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEAC 773
Query: 146 SGGDLYEAI-KDDMVPRKTKNVTNIINQILDAVEYVHSRGIYHRDIKPENILIAGNWNIK 204
GGD++ + K KT I +++A +Y+HS +RD+KPEN+++ + K
Sbjct: 774 MGGDVWTVMSKRQYFDEKTAKF--IAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCK 831
Query: 205 LTDWGLATTDKTSMERN--VGSERYMAPELFESNLDREERTDAYDCAKVDIWAIGIVMLN 262
L D+G A + + + N G+ Y+APE+ LDR +D A VD WA+GI++
Sbjct: 832 LVDFGFAKFVRQNEKTNTFAGTPEYVAPEII---LDR-----GHDRA-VDYWALGILVYE 882
Query: 263 IVFHKNPFTVANQ 275
++ K PF NQ
Sbjct: 883 LLVGKTPFRGVNQ 895
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,197,092
Number of Sequences: 60738
Number of extensions: 2241060
Number of successful extensions: 9684
Number of sequences better than 1.0e-05: 1285
Number of HSP's better than 0.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 1121
Number of HSP's that attempted gapping in prelim test: 7409
Number of HSP's gapped (non-prelim): 1912
length of query: 852
length of database: 30,389,216
effective HSP length: 115
effective length of query: 737
effective length of database: 23,404,346
effective search space: 17249003002
effective search space used: 17249003002
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)