ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4468 good G KOG0602 Carbohydrate transport and metabolism Neutral trehalase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4468 1533054 1535315 754
(754 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR001c [G] KOG0602 Neutral trehalase 1078 0.0
YBR001c [G] KOG0602 Neutral trehalase 1078 0.0
SPBC660.07 [G] KOG0602 Neutral trehalase 812 0.0
ECU02g1370 [G] KOG0602 Neutral trehalase 127 6e-29
7291236 [G] KOG0602 Neutral trehalase 127 8e-29
At4g24040 [G] KOG0602 Neutral trehalase 124 7e-28
Hs6005914 [G] KOG0602 Neutral trehalase 119 2e-26
CE04897 [G] KOG0602 Neutral trehalase 115 3e-25
CE06551 [G] KOG0602 Neutral trehalase 107 5e-23
CE11310 [G] KOG0602 Neutral trehalase 101 5e-21
CE19363 [G] KOG0602 Neutral trehalase 100 6e-21
CE05631 [G] KOG0602 Neutral trehalase 81 5e-15
7302932 [G] KOG0602 Neutral trehalase 53 2e-06
>YDR001c [G] KOG0602 Neutral trehalase
Length = 751
Score = 1078 bits (2788), Expect = 0.0
Identities = 521/749 (69%), Positives = 609/749 (80%), Gaps = 16/749 (2%)
Query: 11 RSRHRRTSSLEEVVDPFSTPDVYYGPKSDPSKLLSKN--RFTRTRTFSVAEPGGGKGHSS 68
+ R RR SSL E DPFS +VYYGP +DP K + RTRT SV +
Sbjct: 13 QGRQRRLSSLSEFNDPFSNAEVYYGPPTDPRKQKQAKPAKINRTRTMSVFDN-------- 64
Query: 69 SYTSPYFDT---TVPLRRRGSEDDSYSASQGQRRFYIEDVDKTLKELLASEDTDGNYQIT 125
SP+ T + RRGSEDD+YS+SQG RRF+IEDVDKTL ELLA+EDTD NYQIT
Sbjct: 65 --VSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDVDKTLNELLAAEDTDKNYQIT 122
Query: 126 IEDTGPKVIRVGTVNSNGYKHVHIRGTYMLSNLLQELTLAKLFNRKQVILDEARLNENPV 185
IEDTGPKV++VGT NS GYKH++IRGTYMLSNLLQELT+AK F R Q+ LDEAR+NENPV
Sbjct: 123 IEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPV 182
Query: 186 NRMTRLISGQFWKSLTRRIDSNNIAKIAYDTKIDTPKAKNPRIYVPYNCQDEYQQLVQWS 245
NR++RLI+ QFW SLTRR+D NN+ +IA DTKIDTP AKNPRIYVPY+C ++Y+ VQ S
Sbjct: 183 NRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPYDCPEQYEFYVQAS 242
Query: 246 EMDPSLQLEVNYLPKDITPEFVKSLNDKPGLLCLAMESHMDPVTGEETWVGFPYAVPGGR 305
+M PSL+LEV YLPK IT E+VKS+ND PGLL LAME H +P TGE+T +G+PYAVPGGR
Sbjct: 243 QMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLALAMEEHFNPSTGEKTLIGYPYAVPGGR 302
Query: 306 FNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLCRSQPPFLT 365
FNELYGWDSY MALGLLE+NK DVARGMVEHFIFEI+HYGKILNANRSYYLCRSQPPFLT
Sbjct: 303 FNELYGWDSYMMALGLLEANKTDVARGMVEHFIFEINHYGKILNANRSYYLCRSQPPFLT 362
Query: 366 DMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCYHPDGIGIP 425
+MAL V +K+GG NP AVDLL+RAF+A+IKEY TVWTASPRLD +TGLS YHP+G+GIP
Sbjct: 363 EMALVVFKKLGGRSNPDAVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIP 422
Query: 426 PETEPGHFDSILRKYAEKYNVSIPEFRDLYNSQKVHEPDLDVFFLHDRGVRESGHDTTYR 485
PETE HFD++L YA K+ V++ EF+ LYN K+ EP LD FFLHDRGVRESGHDTTYR
Sbjct: 423 PETESDHFDTVLLPYASKHGVTLDEFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDTTYR 482
Query: 486 FENVCAYLATIDLNSLLYKYEVDIAYVIKKYFGDNFEG-LPEGHRTSNDWEKLAEVRKER 544
FE VCAYLATIDLNSLLYKYE+DIA IK++ D +E L TS W+++A++R+E+
Sbjct: 483 FEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEK 542
Query: 545 IDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWALWAGMSSQEQAQRMVENALPKLEEFG 604
I KY+WD+E+GF++DYN K + RTSYES TTFWALWAG++++EQAQ+MVE ALPKLE G
Sbjct: 543 ITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWAGLATKEQAQKMVEKALPKLEMLG 602
Query: 605 GLVACTARSRGELSLDRPTRQWDYPFGWAPHQILVWDGLVRYGYENHTRRLAYRWLFLMT 664
GL ACT RSRG +S+ RP RQWDYPFGWAPHQIL W+GL YGY T RLAYRWLF+MT
Sbjct: 603 GLAACTERSRGPISISRPIRQWDYPFGWAPHQILAWEGLRSYGYLTVTNRLAYRWLFMMT 662
Query: 665 KAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNSSYLLGMKYMNN 724
KAFVDYNGIVVEKYDVTRGTDPHRV+AEYGNQGADFKG ATEGFGWVN+SY+LG+KYMN+
Sbjct: 663 KAFVDYNGIVVEKYDVTRGTDPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNS 722
Query: 725 FARRALGTCVTPKVFFGRLPPKEKKKYGL 753
ARRALG C+ P FF L P+E+ YGL
Sbjct: 723 HARRALGACIPPISFFSSLRPQERNLYGL 751
>YBR001c [G] KOG0602 Neutral trehalase
Length = 780
Score = 1078 bits (2787), Expect = 0.0
Identities = 523/745 (70%), Positives = 604/745 (80%), Gaps = 11/745 (1%)
Query: 11 RSRHRRTSSLEEVVDPFSTPDVYYGPKSDPSKLLSKNRFTRTRTFSVAEPGGG-KGHSSS 69
R HRR SS+ E DPFS +VYYGP +DP K +R RTRT SV K
Sbjct: 45 RRHHRRLSSMHEYFDPFSNAEVYYGPITDPRKQSKIHRLNRTRTMSVFNKVSDFKNGMKD 104
Query: 70 YTSPYFDTTVPLRRRGSEDDSYSASQGQRRFYIEDVDKTLKELLASEDTDGNYQITIEDT 129
YT L+RRGSEDDS+ +SQG RRFYI++VD L ELLASEDTD N+QITIEDT
Sbjct: 105 YT---------LKRRGSEDDSFLSSQGNRRFYIDNVDLALDELLASEDTDKNHQITIEDT 155
Query: 130 GPKVIRVGTVNSNGYKHVHIRGTYMLSNLLQELTLAKLFNRKQVILDEARLNENPVNRMT 189
GPKVI+VGT NSNG+KHV++RGTYMLSNLLQELT+AK F R Q+ LDEAR+NENPV+R++
Sbjct: 156 GPKVIKVGTANSNGFKHVNVRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVDRLS 215
Query: 190 RLISGQFWKSLTRRIDSNNIAKIAYDTKIDTPKAKNPRIYVPYNCQDEYQQLVQWSEMDP 249
RLI+ QFW SLTRR+D NIA+IA D+KIDTP AKNPRIYVPYNC ++Y+ +Q S+M+P
Sbjct: 216 RLITTQFWTSLTRRVDLYNIAEIARDSKIDTPGAKNPRIYVPYNCPEQYEFYIQASQMNP 275
Query: 250 SLQLEVNYLPKDITPEFVKSLNDKPGLLCLAMESHMDPVTGEETWVGFPYAVPGGRFNEL 309
SL+LEV YLPKDIT E+VKSLND PGLL LAME H++P TGE + VG+PYAVPGGRFNEL
Sbjct: 276 SLKLEVEYLPKDITAEYVKSLNDTPGLLALAMEEHVNPSTGERSLVGYPYAVPGGRFNEL 335
Query: 310 YGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLCRSQPPFLTDMAL 369
YGWDSY MALGL+ESNK+DVARGMVEHFIFEIDHY KILNANRSYYLCRSQPPFLTDMAL
Sbjct: 336 YGWDSYLMALGLIESNKVDVARGMVEHFIFEIDHYSKILNANRSYYLCRSQPPFLTDMAL 395
Query: 370 QVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCYHPDGIGIPPETE 429
V K+GG NP A+ LL+RAF+AAIKEY VW +SPRLD TGLSCYH DGIGIPPETE
Sbjct: 396 LVFEKIGGKNNPNAIQLLKRAFRAAIKEYKEVWMSSPRLDSLTGLSCYHSDGIGIPPETE 455
Query: 430 PGHFDSILRKYAEKYNVSIPEFRDLYNSQKVHEPDLDVFFLHDRGVRESGHDTTYRFENV 489
P HFD+IL YAEKYNV++ + R LYN + EP LD FFLHDR VRESGHDTTYRFE V
Sbjct: 456 PDHFDTILLPYAEKYNVTLEKLRYLYNEGMIKEPKLDAFFLHDRAVRESGHDTTYRFEGV 515
Query: 490 CAYLATIDLNSLLYKYEVDIAYVIKKYFGDNFEGLPEGHRT-SNDWEKLAEVRKERIDKY 548
CAYLATIDLNSLLYKYE DIA+VIK+YFG+ ++ +G T S WE+LAE+RK RI+KY
Sbjct: 516 CAYLATIDLNSLLYKYEKDIAFVIKEYFGNEYKDENDGTVTDSEHWEELAELRKTRINKY 575
Query: 549 LWDEETGFYYDYNVKTEKRTSYESVTTFWALWAGMSSQEQAQRMVENALPKLEEFGGLVA 608
+WDE++GF++ YN K + RTSYES TTFW+LWAG++++EQA+ VE ALP+LE GGLVA
Sbjct: 576 MWDEDSGFFFYYNTKLKCRTSYESATTFWSLWAGLATEEQAKITVEKALPQLEMLGGLVA 635
Query: 609 CTARSRGELSLDRPTRQWDYPFGWAPHQILVWDGLVRYGYENHTRRLAYRWLFLMTKAFV 668
CT +SRG +S+DRP RQWDYPFGWAPHQIL W GL YGY+ RLAYRWL+++TK+FV
Sbjct: 636 CTEKSRGPISIDRPIRQWDYPFGWAPHQILAWKGLSAYGYQQVATRLAYRWLYMITKSFV 695
Query: 669 DYNGIVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNSSYLLGMKYMNNFARR 728
DYNG+VVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVN+SYLLG+KYMNN ARR
Sbjct: 696 DYNGMVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNTSYLLGLKYMNNHARR 755
Query: 729 ALGTCVTPKVFFGRLPPKEKKKYGL 753
AL C P FF L P EKK Y L
Sbjct: 756 ALAACSPPLPFFNSLKPSEKKLYYL 780
>SPBC660.07 [G] KOG0602 Neutral trehalase
Length = 735
Score = 812 bits (2098), Expect = 0.0
Identities = 410/717 (57%), Positives = 515/717 (71%), Gaps = 22/717 (3%)
Query: 25 DPFSTPDVYYGPKSDPSKLLSKNRFTRTRTFSVAEPGGGKGHSSSYTSPYFDTTVPLRRR 84
+PF+T YY +D S +S R RT S + + +P LRRR
Sbjct: 21 NPFATAKSYYSKDTDLSTRVSAGR---PRTLSTS--------MEASAAPTIPELKNLRRR 69
Query: 85 GSEDDSYSASQGQRRFYIEDVDKTLKELLASEDTDGNYQITIEDTGPKVIRVGTVNSNGY 144
GS D+ Q R ++ DVDKTL LL SEDTD N QITIEDTGPKV+ +G+ +S GY
Sbjct: 70 GSLDE-----HKQPRKFLVDVDKTLNALLESEDTDRNMQITIEDTGPKVVSLGSASSGGY 124
Query: 145 KHVHIRGTYMLSNLLQELTLAKLFNRKQVILDEARLNENPVNRMTRLISGQFWKSLTRRI 204
+ +RGTY LSNLLQELTLAK + R+ ++LDE RLNENPVNR++RLI G FW +LTRRI
Sbjct: 125 RLYELRGTYQLSNLLQELTLAKDYGRRYILLDERRLNENPVNRLSRLIKGTFWDALTRRI 184
Query: 205 DSNNIAKIAYDTKIDTPKAKNPRIYVPYNCQDEYQQLVQWSEMDPSLQLEVNYLPKDITP 264
D++ + I DTK D + RIYVP Q+ Y+ V+ ++ P L L+V YLP++ITP
Sbjct: 185 DASVLDVICRDTK-DRSGSHVNRIYVPKAEQEMYEYYVRAAKERPYLNLQVEYLPEEITP 243
Query: 265 EFVKSLNDKPGLLCLAMESHMDPVTGEETWVGFPYAVPGGRFNELYGWDSYFMALGLLES 324
E+V+ +NDKPGLL LAME + D G G P+ VPGGRFNELYGWDSYF +LGLL
Sbjct: 244 EWVRDVNDKPGLLALAMEKYQDD-EGNTHLRGVPFVVPGGRFNELYGWDSYFESLGLLVD 302
Query: 325 NKLDVARGMVEHFIFEIDHYGKILNANRSYYLCRSQPPFLTDMALQVCRKMGGDKNPVAV 384
+++D+A+GMVE+FIFEI +YGKILNANR+YYL RSQPPFLTDMAL+V ++ ++ ++
Sbjct: 303 DRVDLAKGMVENFIFEITYYGKILNANRTYYLLRSQPPFLTDMALRVYERIKNEEG--SL 360
Query: 385 DLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCYHPDGIGIPPETEPGHFDSILRKYAEKY 444
D L RAF A IKEY TVWTA+PRLD KTGLS Y P G+GIPPETE HF+ +LR Y EKY
Sbjct: 361 DFLHRAFSATIKEYHTVWTATPRLDPKTGLSRYRPGGLGIPPETEASHFEHLLRPYMEKY 420
Query: 445 NVSIPEFRDLYNSQKVHEPDLDVFFLHDRGVRESGHDTTYRFENVCAYLATIDLNSLLYK 504
++++ EF YN Q++HEP LD +F+HDR VRESGHDTTYR E VCA LAT+DLNSLLYK
Sbjct: 421 HMTLEEFTHAYNYQQIHEPALDEYFVHDRAVRESGHDTTYRLEKVCADLATVDLNSLLYK 480
Query: 505 YEVDIAYVIKKYFGDNFEGLPEGH-RTSNDWEKLAEVRKERIDKYLWDEETGFYYDYNVK 563
YE DI++VI +YF D F LP G TS W++ A R+ ++KYLW E +YDYN K
Sbjct: 481 YETDISHVILEYFDDKFV-LPNGTIETSAIWDRRARARRAAMEKYLWSEADSMWYDYNTK 539
Query: 564 TEKRTSYESVTTFWALWAGMSSQEQAQRMVENALPKLEEFGGLVACTARSRGELSLDRPT 623
E +++YES T FWALWAG+++ QA + V+ +LPK E GG+VA T RS G++ LD P+
Sbjct: 540 LETKSTYESATAFWALWAGVATPRQAAKFVDVSLPKFEVAGGIVAGTKRSLGKVGLDNPS 599
Query: 624 RQWDYPFGWAPHQILVWDGLVRYGYENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRG 683
RQWDYP GW+P QIL W GL+RYGYE TRRL YRWL+ +TK+FVD+NGIVVEKYD+TR
Sbjct: 600 RQWDYPNGWSPQQILAWYGLIRYGYEEETRRLVYRWLYTITKSFVDFNGIVVEKYDLTRP 659
Query: 684 TDPHRVDAEYGNQGADFKGVATEGFGWVNSSYLLGMKYMNNFARRALGTCVTPKVFF 740
DPHRV+AEYGNQG + KGVA EGFGWVN+SY +G+ + N+ RRALG C TP VFF
Sbjct: 660 VDPHRVEAEYGNQGVNIKGVAREGFGWVNASYEVGLTFCNSHMRRALGACTTPDVFF 716
>ECU02g1370 [G] KOG0602 Neutral trehalase
Length = 659
Score = 127 bits (319), Expect = 6e-29
Identities = 125/438 (28%), Positives = 191/438 (43%), Gaps = 61/438 (13%)
Query: 298 PYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLC 357
P+ +PG RF E Y WD+Y++ GL++S +A GMVE+FI I+ YG I N R+YYL
Sbjct: 183 PFVIPGDRFKECYYWDTYWIIEGLVKSGMHKIAVGMVENFILLIEKYGFIPNGTRTYYLN 242
Query: 358 RSQPPFLTDMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCY 417
R+QPP+ M V R + + ++++R KAA+ EY EK G S Y
Sbjct: 243 RTQPPYFCMMLFTVYRHVPWTEE--VEEIIKRGLKAAVMEYNFFMNYRKEEIEKDGKS-Y 299
Query: 418 HPDGIGIPPETEPGHFDSILRKYAEKYNVSIPEFR----DLYNSQKVHEPDLDVFFLHDR 473
+ + T S RK AE +R D+Y++ K
Sbjct: 300 VLNVYRVSDCTPRAESYSEDRKVAENNKSKDEVYRRREEDIYSNLKAG------------ 347
Query: 474 GVRESGHDTTYRFENVCAYLATI--------DLNSLLYKYEVDIAYVIKKYFGDNFEGLP 525
ESG D + R+ V L +I DLN+++Y E+ +I K F +
Sbjct: 348 --AESGWDYSSRWLGVRGELDSIRTSKRVPADLNAIMYANEL----IIMKLF-----EVV 396
Query: 526 EGHRTSN--DWEKLAEVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWA-LWAG 582
EG R+ N D++K +E R I+ LW +E G + DY+++ +K TS + A + G
Sbjct: 397 EGKRSKNAEDFKKKSEERYRAINAVLWSDEEGVWNDYDIEKKKHTSPGFYFSNLAPMCYG 456
Query: 583 MSSQEQAQRMVENALPKLEEF-----GGLVACTARSRGELSLDRPTRQWDYPFGWAPHQI 637
+S V + L E GG+ A ++++ QWDYP W P
Sbjct: 457 ISPPPDKNITVYDILNAFAEEIFGHPGGMPASGSKNKNS------PEQWDYPNVWPPLVH 510
Query: 638 LVWDGLVRYGYENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRVDAE-YGNQ 696
++ L R G LA ++ ++ + DVTR + + E G+
Sbjct: 511 IMTFFLERIGERQMALHLA--------RSLLENISVSTSISDVTRRGIFEKYNCERVGDS 562
Query: 697 GADFKGVATEGFGWVNSS 714
G + GFGW N S
Sbjct: 563 GYKGEYAPQVGFGWTNGS 580
>7291236 [G] KOG0602 Neutral trehalase
Length = 596
Score = 127 bits (318), Expect = 8e-29
Identities = 117/425 (27%), Positives = 179/425 (41%), Gaps = 53/425 (12%)
Query: 298 PYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLC 357
P VPGGRF E Y WDSY++ GLL S D ARGM+E+F ++ +G I N R YY
Sbjct: 186 PVIVPGGRFIEFYYWDSYWIIRGLLYSQMFDTARGMIENFFSIVNRFGFIPNGGRVYYHG 245
Query: 358 RSQPPFLTDMALQVCRKMGGDKNPV-AVDLLRRAFKAAIKEY-LTVWTASPRLDEKTGLS 415
RSQPP LT M DK + A+D L F+ + + +TV + L
Sbjct: 246 RSQPPLLTGMVKSYVDFTNDDKFAIDALDTLEHEFEFFVNNHNVTV--------KNHSLC 297
Query: 416 CYHPDGIGIPPETEPGHFDSILRKYAEKYNVSIPEFRDLYNSQKVHEPDLDVFFLHDRGV 475
Y G PE+ ++ E++ E ++L+ S+ + + F +
Sbjct: 298 VYRDSSSGPRPESYREDVET-----GEEFPTD--EAKELHYSELKAGAESGMDFSSRWFI 350
Query: 476 RESGHDTTYRFENVCAYLATIDLNSLLYKYEVDIAYVIKKYFGDNFEGLPEGHRTSNDWE 535
+G + R + +DLN+ LY IA F + ++E
Sbjct: 351 SPTGTNDGNRSALSTTSIVPVDLNAYLYWNAKLIA---------EFHSKAGNTKKVTEYE 401
Query: 536 KLAEVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWALWAGMSSQEQAQRMVEN 595
AE I + LW+EE G + DY++ +K Y + T LW + +++++ +
Sbjct: 402 TKAEKLLLGIQEVLWNEEAGVWLDYDMINQKPRDYYTPTNLSPLWVKAFNISESEKISAS 461
Query: 596 ALP-----KLEEFGGLVACTARSRGELSLDRPTRQWDYPFGWAPHQILVWDGLVRYG--- 647
+ KL+ F G V T GE QWD P WAP Q ++ +GL
Sbjct: 462 VMAYIERNKLDSFPGGVPNTLSYTGE--------QWDAPNVWAPMQYILVEGLNNLNTPE 513
Query: 648 YENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEG 707
+N + + A RW+ AF + + EKY+ E+G G + G
Sbjct: 514 AKNMSLKWATRWVKTNFAAF-SKDRHMYEKYNAD----------EFGVGGGGGEYEVQTG 562
Query: 708 FGWVN 712
FGW N
Sbjct: 563 FGWSN 567
>At4g24040 [G] KOG0602 Neutral trehalase
Length = 626
Score = 124 bits (310), Expect = 7e-28
Identities = 123/455 (27%), Positives = 189/455 (41%), Gaps = 97/455 (21%)
Query: 298 PYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLC 357
P +PG RF E+Y WDSY++ GL+ S A+G+V + + ++ YG LN R+YY
Sbjct: 217 PVIIPGSRFREVYYWDSYWVIKGLMTSQMFTTAKGLVTNLMSLVETYGYALNGARAYYTN 276
Query: 358 RSQPPFLTDMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCY 417
RSQPP L+ M ++ + +L+R+A +KEY W +
Sbjct: 277 RSQPPLLSSMVYEIYNVTKDE------ELVRKAIPLLLKEY-EFWNSGK----------- 318
Query: 418 HPDGIGIPPETEPGHFDSILRKYAEKYNVSIPE-----------FRDLYNSQKVH----- 461
H I + +D +L +Y +N PE F + Q+ H
Sbjct: 319 HKVVI-----RDANGYDHVLSRYYAMWNKPRPESSVFDEESASGFSTMLEKQRFHRDIAT 373
Query: 462 --EPDLDVFFLHDRGVRESGHDTTYRFENVCAYLATIDLNSLLYKYEVDIAYVIKKYFGD 519
E D R +R+ + TT +V +DLN L K E+DIA+++ K GD
Sbjct: 374 AAESGCD---FSTRWMRDPPNFTTMATTSV----VPVDLNVFLLKMELDIAFMM-KVSGD 425
Query: 520 NFEGLPEGHRTSNDWEKLAEVRKERIDKYLWDEETGFYYDY----------NVKTEKRTS 569
S+ + K ++ R++ W+E+ G + DY K E + +
Sbjct: 426 --------QNGSDRFVKASKAREKAFQTVFWNEKAGQWLDYWLSSSGEESETWKAENQNT 477
Query: 570 YESVTTFWALWA-GMSSQEQAQRMVENALPKLEEFGGLVACTARSRGEL-SLDRPTRQWD 627
+ F +W ++S E + V AL GL+A G L SL +QWD
Sbjct: 478 NVFASNFAPIWINSINSDENLVKKVVTALKN----SGLIA----PAGILTSLTNSGQQWD 529
Query: 628 YPFGWAPHQILVWDGLVRYGY---ENHTRRLAYRWL---FLMTKAFVDYNGIVVEKYDVT 681
P GWAP Q ++ GL R + +A RW+ +L+ K +G + EK VT
Sbjct: 530 SPNGWAPQQEMIVTGLGRSSVKEAKEMAEDIARRWIKSNYLVYKK----SGTIHEKLKVT 585
Query: 682 RGTDPHRVDAEYGNQGADFKGVATEGFGWVNSSYL 716
E G G + + GFGW N L
Sbjct: 586 ----------ELGEYGGGGEYMPQTGFGWSNGVIL 610
>Hs6005914 [G] KOG0602 Neutral trehalase
Length = 583
Score = 119 bits (297), Expect = 2e-26
Identities = 114/429 (26%), Positives = 180/429 (41%), Gaps = 67/429 (15%)
Query: 298 PYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLC 357
P+ VPGGRF E Y WDSY++ GLL S + +GM+++F+ + YG + N R YYL
Sbjct: 161 PFIVPGGRFVEFYYWDSYWVMEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQ 220
Query: 358 RSQPPFLTDMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCY 417
RSQPP LT + + D + ++ A + L WT + + Y
Sbjct: 221 RSQPPLLT-LMMDCYLTHTNDTAFLQENIETLALE------LDFWTKNRTVSVSLEGKNY 273
Query: 418 HPDGIGIPPETEPGHFDSILRKYAEKYNVSIPE--FRDLYNSQKVHEPDLDVFFLHDRGV 475
+L +Y Y PE +D+ + + E D + + +
Sbjct: 274 ------------------LLNRYYVPYGGPRPESYSKDVELADTLPEGDREALWAELKAG 315
Query: 476 RESGHDTTYRF------ENVCAYLAT-----IDLNSLLYKYEVDIAYVIKKYFGDNFEGL 524
ESG D + R+ N + + T +DLN+ L + E ++ NF
Sbjct: 316 AESGWDFSSRWLIGGPNPNSLSGIRTSKLVPVDLNAFLCQAEELMS---------NFYSR 366
Query: 525 PEGHRTSNDWEKLAEVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWALWAGMS 584
+ + L R ++ LWDE+TG ++DY+++ +K+ + LWAG
Sbjct: 367 LGNDSQATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTPLWAGCF 426
Query: 585 SQEQAQRMVENALPKLEEFGGLVACTARSRGELSLDRPTRQWDYPFGWAPHQILVWDGLV 644
S + + AL LE+ L T + SL + +QWD+P WAP Q LV GL
Sbjct: 427 SD---PGVADKALKYLEDNRIL---TYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLA 480
Query: 645 RYGYENHTR---RLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGADFK 701
+ +LA W+ + + EKYDV+ G P G +++
Sbjct: 481 KAPLRRAQEVAFQLAQNWIRTNFDVY-SQKSAMYEKYDVSNGGQP--------GGGGEYE 531
Query: 702 GVATEGFGW 710
EGFGW
Sbjct: 532 --VQEGFGW 538
>CE04897 [G] KOG0602 Neutral trehalase
Length = 585
Score = 115 bits (287), Expect = 3e-25
Identities = 112/436 (25%), Positives = 183/436 (41%), Gaps = 70/436 (16%)
Query: 298 PYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLC 357
P+ VPGGRF E+Y WDS+F GL+ S L +GM+E+ I+ ++ YG I N R YYL
Sbjct: 133 PFVVPGGRFREMYYWDSFFTIKGLIASGMLTTVKGMIENMIYLVETYGFIPNGTRVYYLN 192
Query: 358 RSQPPFLTDMALQVCRKMGGDKNPVA--VDLLRRAFKAAIKEYLTVWTASPRLDEKTGLS 415
RSQPP LT ++ + GDK ++ + LR+ F +T +
Sbjct: 193 RSQPPLLT-WCVKAYYEATGDKQFLSDVLPTLRKEFSFF----------------QTHKT 235
Query: 416 CYHPDGIGIPPETEPGHFDSILRKYAEKYNVSIPEF--RDLYNSQKVHEPDLDVFFLHD- 472
HPD +++ L ++ + + PE DL +++ + + D
Sbjct: 236 YNHPD------------WNTPLYRFVVETSHPRPESYREDLESAEHLDTLEKKCVLWGDL 283
Query: 473 RGVRESGHDTTYRFENV----CAYLATIDLNSLLYKYEVDIAYVIKKYFGDNFEGLPEGH 528
ESG D + RF V LA+ + L+ VD+ +I N + L E +
Sbjct: 284 AAAAESGRDFSSRFFAVHGPYAGQLASTRTSQLI---PVDLNSII----CGNMKTLSEMY 336
Query: 529 RTSNDWEKLA------EVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWALWAG 582
D E ++ I + LW+EE ++D++V+ + T F+ ++
Sbjct: 337 TVCGDLESAKYFDNEYRTLRDTIRQVLWNEEHNCWFDFDVEEGNHATSFHDTNFFPMYCD 396
Query: 583 MSSQEQAQRMVENALPK--LEEFGGLVACTARSRGELSLDRPTRQWDYPFGWAPHQILVW 640
++ ++V + L F G + + + GE QWD+P W P ++
Sbjct: 397 SYHEDLDSQVVVDYLTTSGAISFPGGIPVSLVNSGE--------QWDFPNSWPPTTWVLL 448
Query: 641 DGLVRYGYENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGADF 700
+GL + G E L +W+ + G + EKY+V + EY
Sbjct: 449 EGLRKVGQEELALSLVEKWVQKNFNMWRTSGGRMFEKYNVVSPCFKVKGGGEY------- 501
Query: 701 KGVATEGFGWVNSSYL 716
V EGFGW N L
Sbjct: 502 --VMQEGFGWTNGVIL 515
>CE06551 [G] KOG0602 Neutral trehalase
Length = 588
Score = 107 bits (268), Expect = 5e-23
Identities = 116/462 (25%), Positives = 192/462 (41%), Gaps = 74/462 (16%)
Query: 299 YAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLCR 358
+ VPGGRF E Y WD+Y++ GL+ S+ + R M+ + +D YG + N R YYL R
Sbjct: 150 FIVPGGRFREFYYWDAYWIIKGLIASDMYNTTRSMIRNLASMVDKYGFVPNGGRVYYLQR 209
Query: 359 SQPPFLTDMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCYH 418
SQPPFL M ++ + DK VA +LL K L W D + +
Sbjct: 210 SQPPFLAAMVYEL-YEATNDKAFVA-ELLPTLLKE-----LNFWNEKRMTDVQMNGKSFK 262
Query: 419 PDGIGIPPETEPGHFDSILRKYAEKYNVSIPE-FR-DLYNSQKV-HEPDLDVFFLHDRGV 475
+ +Y NV PE +R D NS K+ + D F+
Sbjct: 263 ------------------VYQYKTASNVPRPESYRVDTQNSAKLANGADQQQFYQDLASA 304
Query: 476 RESGHDTTYRFENVCAYLATI--------DLNSLLYKYEVDIAYVIKKYFGDNFEGLPEG 527
ESG D + R+ + L +I DLN LL + +DI + + GD
Sbjct: 305 AESGWDFSTRWFSDYKTLTSIETTKVLPVDLNGLLC-WNMDIMEYLYEQIGDT------- 356
Query: 528 HRTSNDWEKLAEVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWALWAGM--SS 585
+ S + ++ + ++ G +YDYN++T+ +T L+ +
Sbjct: 357 -KNSQIFRNKRADFRDTVQNVFYNRTDGTWYDYNLRTQSHNPRFYTSTAVPLFTNCYNTL 415
Query: 586 QEQAQRMVENALPKLEEF---GGLVACTARSRGELSLDRPTRQWDYPFGWAPHQILVWDG 642
+ V + + K+ F GG+ ++ + QWD+P GW+P+ ++ +G
Sbjct: 416 NTGKSQKVFDYMDKMGVFTYPGGIPTSMSQESDQ--------QWDFPNGWSPNNHMIIEG 467
Query: 643 LVRYG---YENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGAD 699
L + ++ +A +W+ + F + G + EKY+V Y G+
Sbjct: 468 LRKSANPEMQDKGFLIASKWVMGNFRVFYE-TGHMWEKYNVI---------GSYPQPGSG 517
Query: 700 FKGVATEGFGWVNSSYL-LGMKYMNNF--ARRALGTCVTPKV 738
+ +GFGW N + L L + Y + + T VTP V
Sbjct: 518 GEYDVQDGFGWSNGAILDLLLTYNDRLFVPENFVNTTVTPSV 559
>CE11310 [G] KOG0602 Neutral trehalase
Length = 570
Score = 101 bits (251), Expect = 5e-21
Identities = 108/448 (24%), Positives = 189/448 (42%), Gaps = 52/448 (11%)
Query: 294 WVGFPYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRS 353
+V P+ +PGGRF E Y WD++++ GLL S + ARG++++ + +D++G + N R
Sbjct: 134 YVPHPFIIPGGRFLEFYYWDTFWILKGLLFSEMYETARGVIKNLGYMVDNHGFVPNGGRV 193
Query: 354 YYLCRSQPPFLTDMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPR--LDEK 411
YYL RSQPP LT M + G +D + KEY W + + +K
Sbjct: 194 YYLTRSQPPLLTPMVYEYYMSTGD------LDFVMEILPTLDKEY-EFWIKNRQEWFKDK 246
Query: 412 TGLS---CYHPDGIGIPPETEPGHFDSILRKYAEKYNVSIPEFRDLYNSQKVHEPDLDVF 468
G+ Y P E DS L ++ + I + ++ ++ + D
Sbjct: 247 DGVKQFPYYQYKAKLKVPRPESYREDSELAEHLQTEAEKIQMWSEIASAAETGW-DFSTR 305
Query: 469 FLHDRGVRESGHDTTYRFENVCAYLATIDLNSLLYKYEVDIAYVIKKYFGDNFEGLPEGH 528
+ G DT +R +++ Y T + I + + N L +
Sbjct: 306 WFSQNG------DTMHRMDSI-RYRGTWSI----------IPADLNAFMCANARILASLY 348
Query: 529 RTSNDWEKLAEVR------KERIDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWALWAG 582
+ D++K+ K + + W+E G +YDY+++ + ++ V+ L+A
Sbjct: 349 EIAGDFKKVKVFEQRYTWAKREMRELHWNETDGIWYDYDIELKTHSNQYYVSNAVPLYAK 408
Query: 583 MSSQEQAQRMVENALPKLEEFGGLVACTARSRGELSLDRPTRQWDYPFGWAPHQILVWDG 642
+ + + + E GL+ T L++ T+QWD W P +V +G
Sbjct: 409 CYDDDDD---IPHRVHDYLERQGLLKYTKGLPTSLAMS-STQQWDKENAWPPMIHMVIEG 464
Query: 643 LVRYG---YENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGAD 699
G ++A WL ++F+ + + EKY+VT PH + G G +
Sbjct: 465 FRTTGDIKLMKVAEKMATSWLTGTYQSFIRTHA-MFEKYNVT----PHTEETS-GGGGGE 518
Query: 700 FKGVATEGFGWVNSSYL-LGMKYMNNFA 726
++ GFGW N L L KY + FA
Sbjct: 519 YE--VQTGFGWTNGVILDLLDKYGDQFA 544
>CE19363 [G] KOG0602 Neutral trehalase
Length = 684
Score = 100 bits (250), Expect = 6e-21
Identities = 117/447 (26%), Positives = 183/447 (40%), Gaps = 61/447 (13%)
Query: 286 DPVTGEETWVGFPYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYG 345
DP +V + + +PGGRF E Y WD+Y++ GL+ S AR M+ +F I+ YG
Sbjct: 211 DPSRFSLIYVPYQFILPGGRFREFYYWDAYWILKGLIASELYSTARMMILNFAHIIETYG 270
Query: 346 KILNANRSYYLCRSQPPFLTDMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTAS 405
+ N R YYL RSQPPF M + + + DL+ I++ T W+
Sbjct: 271 FVPNGGRVYYLRRSQPPFFAPMVYEY--YLATQDIQLVADLI-----PVIEKEYTFWSER 323
Query: 406 PRLDEKTGLSCYHPDGIGIPPETEPGHFDSILRKYAEKYNVSIPE-FR-DLYNSQKVHEP 463
++ HPD E H + +Y + PE FR D+ +++
Sbjct: 324 ----RTVNVTYEHPD------LNETLH----MFQYRTEAETPRPESFREDVLSAEHFTTK 369
Query: 464 DLDVFFLHDRG-VRESGHDTTYR-FEN-------VCAYLATIDLNSLLYKYEVDIAYVIK 514
D F D G ESG D + R F+N + +DLN+ L Y ++I +
Sbjct: 370 DRKKQFFKDLGSAAESGWDFSSRWFKNHKDISTIETTNIVPVDLNAFLC-YNMNIMQLFY 428
Query: 515 KYFGDNFEGLPEGHRTSNDWEKLAEVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESVT 574
K G+ + L +W +E K + +YDYN++T T
Sbjct: 429 KLTGNPLKHL--------EWSSRFTNFREAFTKVFYVPARKGWYDYNLRTLTHN-----T 475
Query: 575 TFWALWA-GMSSQEQAQRMVENALPKLEEFGGLVACTARSRGELSLDRPT-RQWDYPFGW 632
F+A A + SQ + A+ E A + S++ T +QWD+P GW
Sbjct: 476 DFFASNAVPLFSQCYDPLNSQIAVDVYNEMQNSGAFSIPGGIPTSMNEETNQQWDFPNGW 535
Query: 633 APHQILVWDGLVRYG---YENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRV 689
+P ++ +GL + + LA +WL + F + + + EKY+V
Sbjct: 536 SPMNHMIIEGLRKSNNPILQQKAFTLAEKWLETNMQTF-NVSDEMWEKYNVKEPLGKLAT 594
Query: 690 DAEYGNQGADFKGVATEGFGWVNSSYL 716
EY Q GFGW N + L
Sbjct: 595 GGEYEVQA---------GFGWTNGAAL 612
>CE05631 [G] KOG0602 Neutral trehalase
Length = 638
Score = 81.3 bits (199), Expect = 5e-15
Identities = 100/453 (22%), Positives = 173/453 (38%), Gaps = 82/453 (18%)
Query: 298 PYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLC 357
P+ VPGGRF+ + WD++++ GLL S + +G++ +F + G I N+
Sbjct: 154 PFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIPNSGNLQLSR 213
Query: 358 RSQPPFLTDMALQVCRKMGG----------------DKNPVAVDLLRRAFKAAIKEYLT- 400
RSQPP M + + G + N + F + Y+
Sbjct: 214 RSQPPLFPHMIWEYTKATGNYEKQWIDSMDMEMKFWENNRTIAIGTHKLFLYKVFSYIKF 273
Query: 401 VWTASPRLDEKTGLSCYHPDGIGIP-PETEPGHFDSILRKYAEKYN------VSIPEFRD 453
+W + ++ Y P PE G F+ + K A+ + S E
Sbjct: 274 LWFKNMNSSNYVNVNNYIHTLTNCPRPENFLGDFN--IGKAAKTPSDVWRSISSACESGW 331
Query: 454 LYNSQKVHEPDLDVFFLHDRGVRESGHDTTYRFENVCAYLATIDLNSLLYKYEVDIAYVI 513
++S+ +H D D+ +H + +DLN + Y
Sbjct: 332 DFSSRWMHNNDTDLSSIHTD------------------LIIPVDLNVFIANN-----YRY 368
Query: 514 KKYFGDNFEGLPEGHRTSNDWEKLAEVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESV 573
Y+ ++F + +EKL + I + LWD G ++DY++ +KR
Sbjct: 369 MAYYANHFGRFDKSASYRQKYEKL----RYAIQEVLWDNNLGAWFDYDISIQKRNLNFYP 424
Query: 574 TTFWALWAGMSSQEQAQRMVENALPK---LEEFGGLVACTARSRGELSLDRPTRQWDYPF 630
+ + L + ++ VE+ + K LE GG+ + + T+QWD+P
Sbjct: 425 SNVYPLM--LEGMDKFADRVEDYMKKSGALEFVGGIPSSLPA--------QSTQQWDFPN 474
Query: 631 GWAPHQILVWDGLVRYG---YENHTRRLAYRWLFL----MTKAFVDYNGIVVEKYDVTRG 683
WAP+Q V + + ++ A ++ M +G V EKYD R
Sbjct: 475 VWAPNQHFVIQSFMACNNSFLQQEAKKQAMEFIETVYNGMYNPIAGLDGGVWEKYD-ARS 533
Query: 684 TDPHRVDAEYGNQGADFKGVATEGFGWVNSSYL 716
T+ G GA + V EGFGW N + +
Sbjct: 534 TN--------GAPGAGGEYVVQEGFGWTNGAVM 558
>7302932 [G] KOG0602 Neutral trehalase
Length = 332
Score = 53.1 bits (126), Expect = 2e-06
Identities = 37/146 (25%), Positives = 66/146 (44%), Gaps = 7/146 (4%)
Query: 227 RIYVPYNCQDEYQQLVQWSEMDPSLQLEVNYLPKDITPEFVKSLNDKPGLLC-----LAM 281
+++V + D +L W+ P + + ++L + PE + +D GL +
Sbjct: 41 QMFVEKHFNDPGSELEHWTP--PDWKAQPSFLARISDPEIKQFGSDVNGLWKELGRRIKD 98
Query: 282 ESHMDPVTGEETWVGFPYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEI 341
E +P +V P+ VP E W+S+++ GLL+ ARGM+++++ +
Sbjct: 99 EVKENPDQYSIIYVPNPFIVPSSNCREYRYWESFWIIRGLLQCGMHQTARGMIDNYLELV 158
Query: 342 DHYGKILNANRSYYLCRSQPPFLTDM 367
YG + R Y RS PP L M
Sbjct: 159 QQYGFVPGCGRIYCSGRSNPPLLIMM 184
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,975,822
Number of Sequences: 60738
Number of extensions: 2369894
Number of successful extensions: 5407
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5363
Number of HSP's gapped (non-prelim): 19
length of query: 754
length of database: 30,389,216
effective HSP length: 114
effective length of query: 640
effective length of database: 23,465,084
effective search space: 15017653760
effective search space used: 15017653760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)