ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4476.1 suspect: Pn B KOG1756 Chromatin structure and dynamics Histone 2A
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4476.1 1538157 1538474 106
(106 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
Hs22060699 [B] KOG1756 Histone 2A 39 0.001
CE00659 [S] KOG1590 Uncharacterized conserved protein 31 0.33
At5g62110 [K] KOG1601 GATA-4/5/6 transcription factors 28 1.6
7297710 [Z] KOG2065 Gamma-tubulin ring complex protein 28 1.6
Hs17647115 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 28 2.1
SPBC15C4.06c [O] KOG0800 FOG: Predicted E3 ubiquitin ligase 28 2.8
At5g09410 [S] KOG0520 Uncharacterized conserved protein contains... 28 2.8
At3g09830 [T] KOG1187 Serine/threonine protein kinase 27 3.6
Hs9506673 [S] KOG1008 Uncharacterized conserved protein contains... 27 4.7
Hs10190746 [Q] KOG1208 Dehydrogenases with different specificiti... 27 4.7
At4g36580 [O] KOG0742 AAA+-type ATPase 27 4.7
At3g63080 [O] KOG1651 Glutathione peroxidase 27 6.1
At3g17760 [E] KOG1383 Glutamate decarboxylase/sphingosine phosph... 27 6.1
Hs9955960 [Q] KOG0054 Multidrug resistance-associated protein/mi... 26 8.0
Hs9955958 [Q] KOG0054 Multidrug resistance-associated protein/mi... 26 8.0
Hs9955956 [Q] KOG0054 Multidrug resistance-associated protein/mi... 26 8.0
Hs9955954 [Q] KOG0054 Multidrug resistance-associated protein/mi... 26 8.0
Hs9955952 [Q] KOG0054 Multidrug resistance-associated protein/mi... 26 8.0
Hs9955950 [Q] KOG0054 Multidrug resistance-associated protein/mi... 26 8.0
Hs4826838 [Q] KOG0054 Multidrug resistance-associated protein/mi... 26 8.0
Hs19923381 [PT] KOG2301 Voltage-gated Ca2+ channels alpha1 subunits 26 8.0
CE28049 [T] KOG1217 Fibrillins and related proteins containing C... 26 8.0
At1g65960 [E] KOG1383 Glutamate decarboxylase/sphingosine phosph... 26 8.0
>Hs22060699 [B] KOG1756 Histone 2A
Length = 227
Score = 38.9 bits (89), Expect = 0.001
Identities = 17/42 (40%), Positives = 29/42 (68%)
Query: 60 NSFKDIVNERVQDRHRLLGNTSVWMGLLQNLVDVRRVSFLSS 101
N+ K++ N+R+ D H L ++SV + LLQ LVDV R++ ++
Sbjct: 71 NALKNVTNKRIHDTHGLGRDSSVRVDLLQQLVDVNRIALFAA 112
>CE00659 [S] KOG1590 Uncharacterized conserved protein
Length = 160
Score = 30.8 bits (68), Expect = 0.33
Identities = 22/76 (28%), Positives = 36/76 (46%), Gaps = 6/76 (7%)
Query: 22 NSVLSQFTWQDQSNSSLNFSSRDGRLLVVSSQLGRFGSNSFKDIVNERVQDRHRLLGNTS 81
+SV +F W Q + L F+ +QLGRF ++++ V + V H+L+
Sbjct: 65 SSVFMRFAWHVQPRNLLLFACHFANFSAQGAQLGRFVNHNYLHYVEDPV--HHKLMMKKE 122
Query: 82 VWMGLLQNLVDVRRVS 97
V L++ D RVS
Sbjct: 123 V----LEHEHDAERVS 134
>At5g62110 [K] KOG1601 GATA-4/5/6 transcription factors
Length = 691
Score = 28.5 bits (62), Expect = 1.6
Identities = 21/96 (21%), Positives = 37/96 (37%), Gaps = 15/96 (15%)
Query: 9 GGRVLGNSSSTFRNSVLSQFTWQDQSNSSLNFSSRDGRLLVVSSQLGRFGSNSFKDIVNE 68
GG ++ ++ + L W +N N+ S R S+ F ++
Sbjct: 180 GGAIVDSNGNGHLGESLGAMNWNLNNNDVRNYESSTSRF-----------SSPFSSFLHN 228
Query: 69 RVQDRHRLLGNTSVWMGLLQ-NLVDVRRVSFLSSLG 103
+VQ H L+ T GLL +++D +V G
Sbjct: 229 KVQPHHNLISQTD---GLLSTSILDTSQVPSFGQYG 261
>7297710 [Z] KOG2065 Gamma-tubulin ring complex protein
Length = 648
Score = 28.5 bits (62), Expect = 1.6
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Query: 1 MIVCLSLSGGRVLGNSSSTFRNSVLSQFTWQDQSNSSLNFSSRDGRLLVVSSQLGRFG-- 58
M V S S V+ + + F +VLS ++S + LN + R + + L FG
Sbjct: 518 MNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGIC 577
Query: 59 -----SNSFKDIVNERVQDRHRLLGNTSVWMG-LLQNLVDVRRVSFLSSLGSLL 106
KD ++ + +L + V + L+Q LVDV+ S L L LL
Sbjct: 578 EKFAHMTQTKDPSDDLEDEVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLL 631
>Hs17647115 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 2277
Score = 28.1 bits (61), Expect = 2.1
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
Query: 29 TWQDQSNSSLNFSSRDGRLLVVSSQLGRFGSNSFKDIVNERVQDRHRLLGNTSVWMGLL- 87
T D S SS NF+ RD ++L +L FG K I+ ++ H N W GL+
Sbjct: 1376 TPDDLSVSSSNFTDRDDKILTRGERLDGFGL-LLKKIMAILIKRFHHTRRN---WKGLIA 1431
Query: 88 QNLVDVRRVSFLSSLGSL 105
Q ++ + V+ LG+L
Sbjct: 1432 QVILPIVFVTTAMGLGTL 1449
>SPBC15C4.06c [O] KOG0800 FOG: Predicted E3 ubiquitin ligase
Length = 556
Score = 27.7 bits (60), Expect = 2.8
Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 13 LGNSSSTFRNSVLSQF---TWQDQSNSSLNFSSRDGRLLVVSSQLGRFGSNSFKDIVNER 69
+ +SS + +SV S+ ++ D S SS SS G + + + SN+ ++
Sbjct: 94 MSSSSESDSDSVSSESNPKSYSDSSTSSARSSSTSGSISLYDDYYPAYSSNAPNTAISNY 153
Query: 70 VQDRHRLLGNTSVWMGLLQ 88
V GN+S+ M ++
Sbjct: 154 VSSGLSYYGNSSIIMNAVE 172
>At5g09410 [S] KOG0520 Uncharacterized conserved protein contains IPT/TIG
domain
Length = 1007
Score = 27.7 bits (60), Expect = 2.8
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 6 SLSGGRVLGNSSSTFRNSVLSQFTWQDQSNSSLNFSSRDGRLLVVSSQLG 55
S GGR+ + RN + +QF WQD ++ +L S SS LG
Sbjct: 274 SEKGGRL---KAEHIRNPLQTQFNWQDDTDLALFEQSAQDNFETFSSLLG 320
>At3g09830 [T] KOG1187 Serine/threonine protein kinase
Length = 418
Score = 27.3 bits (59), Expect = 3.6
Identities = 17/56 (30%), Positives = 25/56 (44%)
Query: 4 CLSLSGGRVLGNSSSTFRNSVLSQFTWQDQSNSSLNFSSRDGRLLVVSSQLGRFGS 59
C SGG G + S+ S F+ ++ + S F+SRD S +GR S
Sbjct: 3 CFLFSGGDKRGEQKTPISVSLTSIFSDREINRSGSEFNSRDVSGTSTESSMGRKNS 58
>Hs9506673 [S] KOG1008 Uncharacterized conserved protein contains WD40 repeats
Length = 567
Score = 26.9 bits (58), Expect = 4.7
Identities = 13/41 (31%), Positives = 21/41 (50%)
Query: 49 VVSSQLGRFGSNSFKDIVNERVQDRHRLLGNTSVWMGLLQN 89
VV + LG+ ++ FKD++ + +H NT W L N
Sbjct: 87 VVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSN 127
>Hs10190746 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 336
Score = 26.9 bits (58), Expect = 4.7
Identities = 12/29 (41%), Positives = 21/29 (72%)
Query: 41 SSRDGRLLVVSSQLGRFGSNSFKDIVNER 69
SS R++VVSS+L ++G +F D+ +E+
Sbjct: 181 SSAPSRIVVVSSKLYKYGDINFDDLNSEQ 209
>At4g36580 [O] KOG0742 AAA+-type ATPase
Length = 620
Score = 26.9 bits (58), Expect = 4.7
Identities = 16/43 (37%), Positives = 22/43 (50%), Gaps = 7/43 (16%)
Query: 40 FSSRDGRLLVVSSQLGRFG-------SNSFKDIVNERVQDRHR 75
FS R+ LV Q G +G S FK+IV +V++ HR
Sbjct: 563 FSGREIAKLVAGVQAGVYGRADCVLDSQLFKEIVEYKVEEHHR 605
>At3g63080 [O] KOG1651 Glutathione peroxidase
Length = 173
Score = 26.6 bits (57), Expect = 6.1
Identities = 13/44 (29%), Positives = 24/44 (54%)
Query: 15 NSSSTFRNSVLSQFTWQDQSNSSLNFSSRDGRLLVVSSQLGRFG 58
+SSS+ + QFT +D S ++ S G++L+V + + G
Sbjct: 4 SSSSSVSEKSIHQFTVKDSSGKEVDLSVYQGKVLLVVNVASKCG 47
>At3g17760 [E] KOG1383 Glutamate decarboxylase/sphingosine phosphate lyase
Length = 494
Score = 26.6 bits (57), Expect = 6.1
Identities = 13/45 (28%), Positives = 22/45 (48%)
Query: 32 DQSNSSLNFSSRDGRLLVVSSQLGRFGSNSFKDIVNERVQDRHRL 76
DQ +LNFS +++ Q R G +K+I+ + + RL
Sbjct: 309 DQPTFTLNFSKGSSQIIAQYYQFIRLGFEGYKNIMENCMDNARRL 353
>Hs9955960 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1482
Score = 26.2 bits (56), Expect = 8.0
Identities = 17/45 (37%), Positives = 23/45 (50%), Gaps = 6/45 (13%)
Query: 14 GNSSSTFRNSVLSQFTWQDQSNSSLN---FSSRDGRLLVVSSQLG 55
G +S T RN+ FTW +LN FS +G L+ V Q+G
Sbjct: 591 GTNSITVRNAT---FTWARSDPPTLNGITFSIPEGALVAVVGQVG 632
>Hs9955958 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1489
Score = 26.2 bits (56), Expect = 8.0
Identities = 17/45 (37%), Positives = 23/45 (50%), Gaps = 6/45 (13%)
Query: 14 GNSSSTFRNSVLSQFTWQDQSNSSLN---FSSRDGRLLVVSSQLG 55
G +S T RN+ FTW +LN FS +G L+ V Q+G
Sbjct: 598 GTNSITVRNAT---FTWARSDPPTLNGITFSIPEGALVAVVGQVG 639
>Hs9955956 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1466
Score = 26.2 bits (56), Expect = 8.0
Identities = 17/45 (37%), Positives = 23/45 (50%), Gaps = 6/45 (13%)
Query: 14 GNSSSTFRNSVLSQFTWQDQSNSSLN---FSSRDGRLLVVSSQLG 55
G +S T RN+ FTW +LN FS +G L+ V Q+G
Sbjct: 640 GTNSITVRNAT---FTWARSDPPTLNGITFSIPEGALVAVVGQVG 681
>Hs9955954 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1416
Score = 26.2 bits (56), Expect = 8.0
Identities = 17/45 (37%), Positives = 23/45 (50%), Gaps = 6/45 (13%)
Query: 14 GNSSSTFRNSVLSQFTWQDQSNSSLN---FSSRDGRLLVVSSQLG 55
G +S T RN+ FTW +LN FS +G L+ V Q+G
Sbjct: 640 GTNSITVRNAT---FTWARSDPPTLNGITFSIPEGALVAVVGQVG 681
>Hs9955952 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1475
Score = 26.2 bits (56), Expect = 8.0
Identities = 17/45 (37%), Positives = 23/45 (50%), Gaps = 6/45 (13%)
Query: 14 GNSSSTFRNSVLSQFTWQDQSNSSLN---FSSRDGRLLVVSSQLG 55
G +S T RN+ FTW +LN FS +G L+ V Q+G
Sbjct: 640 GTNSITVRNAT---FTWARSDPPTLNGITFSIPEGALVAVVGQVG 681
>Hs9955950 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1472
Score = 26.2 bits (56), Expect = 8.0
Identities = 17/45 (37%), Positives = 23/45 (50%), Gaps = 6/45 (13%)
Query: 14 GNSSSTFRNSVLSQFTWQDQSNSSLN---FSSRDGRLLVVSSQLG 55
G +S T RN+ FTW +LN FS +G L+ V Q+G
Sbjct: 640 GTNSITVRNAT---FTWARSDPPTLNGITFSIPEGALVAVVGQVG 681
>Hs4826838 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1531
Score = 26.2 bits (56), Expect = 8.0
Identities = 17/45 (37%), Positives = 23/45 (50%), Gaps = 6/45 (13%)
Query: 14 GNSSSTFRNSVLSQFTWQDQSNSSLN---FSSRDGRLLVVSSQLG 55
G +S T RN+ FTW +LN FS +G L+ V Q+G
Sbjct: 640 GTNSITVRNAT---FTWARSDPPTLNGITFSIPEGALVAVVGQVG 681
>Hs19923381 [PT] KOG2301 Voltage-gated Ca2+ channels alpha1 subunits
Length = 2000
Score = 26.2 bits (56), Expect = 8.0
Identities = 11/32 (34%), Positives = 17/32 (52%)
Query: 15 NSSSTFRNSVLSQFTWQDQSNSSLNFSSRDGR 46
+S+ TF N +S F W+D +F DG+
Sbjct: 300 DSNGTFVNVTMSTFNWKDYIGDDSHFYVLDGQ 331
>CE28049 [T] KOG1217 Fibrillins and related proteins containing Ca2+-binding
EGF-like domains
Length = 3767
Score = 26.2 bits (56), Expect = 8.0
Identities = 23/90 (25%), Positives = 39/90 (42%), Gaps = 3/90 (3%)
Query: 3 VCLSLSGGRVLGNSSSTFRNSVLSQFTWQDQSNSSLNFSSRDGRLLVVSSQLGRFGSNSF 62
VC+S G G R++ + ++ L +RD R L+ S++ G S S+
Sbjct: 2849 VCIS---GEYCGCKPGEGRSASTGKCQEVQETPFELRVVTRDQRPLMYSTEFGSQKSPSY 2905
Query: 63 KDIVNERVQDRHRLLGNTSVWMGLLQNLVD 92
+IV ++ R G TS+ + VD
Sbjct: 2906 VEIVELFEKNMARTFGGTSLAPRYVNTKVD 2935
>At1g65960 [E] KOG1383 Glutamate decarboxylase/sphingosine phosphate lyase
Length = 494
Score = 26.2 bits (56), Expect = 8.0
Identities = 11/41 (26%), Positives = 22/41 (52%)
Query: 32 DQSNSSLNFSSRDGRLLVVSSQLGRFGSNSFKDIVNERVQD 72
DQ +LNFS +++ QL R G +K+++ +++
Sbjct: 309 DQPTFTLNFSKGSSQIIAQYYQLIRLGFEGYKNVMENCIEN 349
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.133 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,669,999
Number of Sequences: 60738
Number of extensions: 191099
Number of successful extensions: 530
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 519
Number of HSP's gapped (non-prelim): 27
length of query: 106
length of database: 30,389,216
effective HSP length: 82
effective length of query: 24
effective length of database: 25,408,700
effective search space: 609808800
effective search space used: 609808800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)