ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4523 check: MH C KOG2451 Energy production and conversion Aldehyde dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4523 1553982 1555472 497
(497 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR006w [C] KOG2451 Aldehyde dehydrogenase 751 0.0
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 513 e-145
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 461 e-129
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 455 e-128
7301355 [C] KOG2451 Aldehyde dehydrogenase 442 e-124
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 433 e-121
CE10542 [C] KOG2451 Aldehyde dehydrogenase 396 e-110
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 302 9e-82
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 295 1e-79
7297513 [C] KOG2450 Aldehyde dehydrogenase 290 3e-78
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 289 6e-78
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 287 2e-77
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 287 3e-77
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 286 4e-77
YER073w [C] KOG2450 Aldehyde dehydrogenase 285 1e-76
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 285 1e-76
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 284 2e-76
7301524 [C] KOG2450 Aldehyde dehydrogenase 282 9e-76
CE29393 [C] KOG2450 Aldehyde dehydrogenase 280 3e-75
CE23852 [C] KOG2450 Aldehyde dehydrogenase 280 5e-75
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 279 6e-75
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 278 1e-74
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 277 3e-74
YOR374w [C] KOG2450 Aldehyde dehydrogenase 273 4e-73
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 272 1e-72
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 271 2e-72
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 270 4e-72
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 270 4e-72
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 268 2e-71
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 268 2e-71
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 267 2e-71
CE24573 [C] KOG2450 Aldehyde dehydrogenase 267 2e-71
YPL061w [C] KOG2450 Aldehyde dehydrogenase 264 3e-70
CE07233 [C] KOG2450 Aldehyde dehydrogenase 257 3e-68
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 251 2e-66
YMR170c [C] KOG2450 Aldehyde dehydrogenase 246 7e-65
CE06980 [C] KOG2450 Aldehyde dehydrogenase 245 1e-64
YMR169c [C] KOG2450 Aldehyde dehydrogenase 244 2e-64
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 232 1e-60
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 201 2e-51
CE01232 [C] KOG2453 Aldehyde dehydrogenase 200 5e-51
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 194 2e-49
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 193 6e-49
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 190 4e-48
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 189 1e-47
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 186 9e-47
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 183 6e-46
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 179 6e-45
7293810 [C] KOG2453 Aldehyde dehydrogenase 179 8e-45
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 178 1e-44
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 166 7e-41
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 156 8e-38
CE13415 [C] KOG2456 Aldehyde dehydrogenase 149 9e-36
CE27441 [C] KOG2456 Aldehyde dehydrogenase 146 8e-35
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 144 2e-34
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 144 2e-34
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 138 2e-32
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 138 2e-32
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 131 2e-30
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 131 2e-30
YMR110c [C] KOG2456 Aldehyde dehydrogenase 126 9e-29
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 125 2e-28
Hs20546780 [C] KOG2450 Aldehyde dehydrogenase 120 4e-27
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 109 1e-23
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 102 1e-21
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 100 5e-21
7304212 [C] KOG2456 Aldehyde dehydrogenase 98 2e-20
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 91 4e-18
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 91 5e-18
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 83 8e-16
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 77 6e-14
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 70 9e-12
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 67 5e-11
Hs20479244 [C] KOG2450 Aldehyde dehydrogenase 67 8e-11
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 50 8e-06
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 751 bits (1938), Expect = 0.0
Identities = 354/486 (72%), Positives = 421/486 (85%)
Query: 9 PEFKNSDLIRKGAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAF 68
P + +L R+ ++DG+W++ E F V DPA+ E+IA +P+Q + V+ EAID A E F
Sbjct: 9 PTLNDPNLFRESGYIDGKWVKGTDEVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETF 68
Query: 69 RLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAE 128
+ +K TTP+ R+ WLRN+YNLM+EN+DDLA IIT ENGKAL EA+GE+KYAASYFEWYAE
Sbjct: 69 KTYKNTTPRERAKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFEWYAE 128
Query: 129 EAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKP 188
EA R+YG TIQP N NR FT+RQPVGVCGIICPWNFPSAMITRKA AALA GCTVV+KP
Sbjct: 129 EAPRLYGATIQPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKP 188
Query: 189 DSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGK 248
DSQTPLSALA+A+LAEKAGFPKG FNV+L+ TP+ G LCESPKVKK++FTGSTNVGK
Sbjct: 189 DSQTPLSALAMAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGK 248
Query: 249 ILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQR 308
ILMKQS+ST+KKLSFELGGNAP IVF+DADL+QA+ Q + KFRGLGQTCVCANR+YV
Sbjct: 249 ILMKQSSSTLKKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHS 308
Query: 309 TIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGG 368
+IID FA+ LA++V +FVIGHGLD KTTHGC+IN +AI+KVE H +DA++KGAK V+ GG
Sbjct: 309 SIIDKFAKLLAERVKKFVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGG 368
Query: 369 RLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYV 428
RL ELGPNFYAP +LSHVPSTA+V+K+ETFGPLC + FDTMEEVVGYANDTE GLA+YV
Sbjct: 369 RLTELGPNFYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYV 428
Query: 429 FSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTI 488
FSKN++T+YTV+EALETGMVSCNTG+FS+C+IPFGGVKESGFGREGSL+GIEDYTV+KTI
Sbjct: 429 FSKNVNTLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTI 488
Query: 489 TIGNLP 494
TIGNLP
Sbjct: 489 TIGNLP 494
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 513 bits (1322), Expect = e-145
Identities = 257/474 (54%), Positives = 345/474 (72%), Gaps = 2/474 (0%)
Query: 21 AFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTR 79
+++ G+W+ AS +TF+V +P E +A + D S+E +AI A EAF ++ + K R
Sbjct: 26 SYIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVEETRKAIKVAHEAFLSYRNSDIKER 85
Query: 80 STWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQ 139
LR Y+L+MEN DDLA ++T ENGKAL +A+GEV YAA + +W+A EA+R+ G +
Sbjct: 86 YAILRRWYDLIMENADDLATMMTLENGKALGDAKGEVVYAAKFIDWFAGEALRISGDSSM 145
Query: 140 PNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALAL 199
+N NR T++QPVGV GII PWNFP+AMITRK GAALAAGCTVV++P ++TP +ALAL
Sbjct: 146 SSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPFTALAL 205
Query: 200 AHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMK 259
A LAE+AG P GV N+V TA E G+ L +P ++K+SFTGSTNVGKIL KQS+ST+K
Sbjct: 206 AKLAERAGVPAGVLNMV-TANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQSSSTLK 264
Query: 260 KLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLA 319
KLS ELGGNAP IVF+DADLE+A + KFRG GQTCVCANRIYV ++ D+F + +
Sbjct: 265 KLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAFVDLVT 324
Query: 320 KQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYA 379
++V++F +G+GLD+ THG LI+E AI KV+ HV+DA++KG V G LGP ++
Sbjct: 325 ERVSKFKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLGPMYFE 384
Query: 380 PTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTV 439
PTV+ + +++++ETFGP+ AL FDT +EVV +AND+ +GLA Y+FSK+I V+ V
Sbjct: 385 PTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAGYLFSKDISRVFRV 444
Query: 440 AEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITIGNL 493
EAL+ GMV CNTGL S+ PFGGVKESGFGREGS +GI +Y IK++TI L
Sbjct: 445 GEALQVGMVGCNTGLVSDVLSPFGGVKESGFGREGSKYGISEYLDIKSLTISTL 498
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 461 bits (1185), Expect = e-129
Identities = 241/480 (50%), Positives = 322/480 (66%), Gaps = 4/480 (0%)
Query: 16 LIRKGAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTT 75
L+R +FV G+WL A+ TF V DPA+ + + D + A+ +A EAF +++ +
Sbjct: 58 LLRTDSFVGGRWLPAAA-TFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVS 116
Query: 76 PKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYG 135
K RS+ LR YNLM++N DDLA+IIT E+GK L EA GE+ Y+A + EW++EEA R+YG
Sbjct: 117 AKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYG 176
Query: 136 TTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLS 195
I RA ++QP+GV +I PWNFPSAMITRK GAALAAGCTVVVKP TP S
Sbjct: 177 DIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFS 236
Query: 196 ALALAHLAEKAGFPKGVFNVV-LTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQS 254
ALALA LA +AG P GV+NV+ + E G A+C P V KISFTGST GKIL+ +
Sbjct: 237 ALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHA 296
Query: 255 ASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSF 314
A+++K++S ELGG AP IVFD A+++QAV + SKFR GQTCVC+N+ VQR I D+F
Sbjct: 297 ANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAF 356
Query: 315 AEKLAKQVNEFV-IGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPEL 373
+ A+ + + + +G+G + TT G LINE A++KVE V DA+ KGA TVV GG+ +L
Sbjct: 357 VKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGA-TVVTGGKRHQL 415
Query: 374 GPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNI 433
G NF+ PT+L +V + +ETFGPL +I FDT EE + AN ++GLA Y +S++
Sbjct: 416 GKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDP 475
Query: 434 DTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITIGNL 493
++ VAE LE GMV N GL S PFGGVK+SG GREGS +GI++Y +K + G L
Sbjct: 476 AQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 535
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 455 bits (1170), Expect = e-128
Identities = 241/488 (49%), Positives = 325/488 (66%), Gaps = 4/488 (0%)
Query: 7 ITPEFKNSDLIRKGAFVDGQWLETA-SETFNVTDPATLEVIATLPDQSIEVIHEAIDSAA 65
++ + ++S L+R + G+WL++ ++T V +PAT E+IA + + ++AI S+
Sbjct: 41 VSEKLRSSGLLRTQGLIGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSY 100
Query: 66 EAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEW 125
EAF + + T RS LR Y+L++ + ++L ++IT E GK L EA GEV Y AS+ E+
Sbjct: 101 EAFTSWSRLTAGERSKVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAYGASFIEY 160
Query: 126 YAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVV 185
YAEEA R+YG I PN R ++QPVGV G I PWNFP AMITRK G ALA+GCTVV
Sbjct: 161 YAEEAKRVYGDIIPPNLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVV 220
Query: 186 VKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTN 245
VKP TPL+ALA A LA +AG P G NVV+ PE G AL SP+V+KI+FTGST
Sbjct: 221 VKPSELTPLTALAAAELALQAGVPPGALNVVM--GNAPEIGDALLTSPQVRKITFTGSTA 278
Query: 246 VGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIY 305
VGK LM +A T+KK+S ELGGNAP IVFDDADL+ AV T+ +KFR GQTCVCANR+
Sbjct: 279 VGKKLMAAAAPTVKKVSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVL 338
Query: 306 VQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVV 365
VQ I D FAE ++ V + +G G TT G LIN+ A++KVE V+DA+ KGAK ++
Sbjct: 339 VQDGIYDKFAEAFSEAVQKLEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAK-II 397
Query: 366 AGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLA 425
GG+ LG FY PTV+ V +++K+E FGP+ LI F T E+ + ANDT GLA
Sbjct: 398 IGGKRHSLGMTFYEPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLA 457
Query: 426 SYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVI 485
+Y+F+ ++ + V EALE G+V N GL S PFGGVK+SG GREGS +G+++Y I
Sbjct: 458 AYIFTNSVQRSWRVFEALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEI 517
Query: 486 KTITIGNL 493
K + +G++
Sbjct: 518 KYVCLGDM 525
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 442 bits (1136), Expect = e-124
Identities = 234/484 (48%), Positives = 314/484 (64%), Gaps = 5/484 (1%)
Query: 14 SDLIRKGAFVDGQWLET--ASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAF--R 69
S L++ A VDG W+++ A TF V +PA VI +P+ ++ +AID+A +A+ +
Sbjct: 24 SALVQDKALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESK 83
Query: 70 LFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEE 129
++ T K RS L+ + L+ ++ ++A+I+T E+GK ++E++GEV Y ++ EW+AEE
Sbjct: 84 EWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEE 143
Query: 130 AVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPD 189
A R+YG + + + ++QP+GV +I PWNFP AMITRKAGAALAAGCTVVVKP
Sbjct: 144 ARRIYGEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPS 203
Query: 190 SQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKI 249
TPL+ALA+A LA AG PKGV NVV T P G C+SP V+ ISFTGST VGK+
Sbjct: 204 EDTPLTALAVAKLAVDAGIPKGVINVVTTNKAAP-IGDLFCKSPDVRGISFTGSTEVGKL 262
Query: 250 LMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRT 309
L + SA +K++ ELGGNAP IVFD AD+E+AV + SKFR GQTCV ANR +VQ +
Sbjct: 263 LFRNSADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDS 322
Query: 310 IIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGR 369
+ D F +L K+V IG G G LINE KV V+DA K A ++ G
Sbjct: 323 VYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQP 382
Query: 370 LPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVF 429
LP+ G FYAPT+++ VP +A + +E FGP+ ++I F EE V ANDT GLA Y +
Sbjct: 383 LPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFY 442
Query: 430 SKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTIT 489
S+N+ V+ VA+ LE GMV N G+ S PFGGVKESG GREGS HGI+DY IK I
Sbjct: 443 SENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYIC 502
Query: 490 IGNL 493
+GNL
Sbjct: 503 MGNL 506
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 433 bits (1113), Expect = e-121
Identities = 227/494 (45%), Positives = 311/494 (62%), Gaps = 8/494 (1%)
Query: 7 ITPEFKNSDLI-----RKGAFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEA 60
+ P+FK +L +FV G+W+ + + +TF V +PAT E+I + D S+E +A
Sbjct: 1 MAPQFKRPELFGFDKSHAQSFVQGKWISSPNNKTFEVDNPATGEIIGKVADVSVEETKKA 60
Query: 61 IDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAA 120
I +A EAF+ +K T RS L L+MEN DDL K++T ENGK LS+A+ EV +
Sbjct: 61 ISAANEAFKTYKNFTHVQRSQLLERWAELIMENKDDLVKMLTLENGKPLSQAEMEVTTCS 120
Query: 121 SYFEWYAEEAVRMYGTTIQPN-NGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALA 179
Y +WYA EAVR +G + N +++QPVGV +I PWNFP+AMI RK GAALA
Sbjct: 121 GYLKWYAAEAVRTFGDVAPSSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALA 180
Query: 180 AGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKIS 239
AGCT + P +TP L L LA++AGFP GV NV+ T++ G L +P V+K+S
Sbjct: 181 AGCTAIFLPAFRTPYVCLGLVRLAQEAGFPDGVLNVI-TSSDASAHGKELTTNPIVRKVS 239
Query: 240 FTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCV 299
FTGSTNVGKILM QSAST+KK+S ELGGNAP IVF D ++QAV KF GQ CV
Sbjct: 240 FTGSTNVGKILMGQSASTIKKVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCV 299
Query: 300 CANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEK 359
C NR+YV + + D F KL ++V +G G DS + G LI+++ KKV H++DA+ K
Sbjct: 300 CPNRVYVHKNVYDEFVSKLTEKVKTIKVGDGFDSSSAVGPLISQDGCKKVSKHIEDAVSK 359
Query: 360 GAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYAND 419
GAK V G + F+ PTVLS V +V +ETFGPL ++ FD EEV+ +AND
Sbjct: 360 GAKITVGGKEISSSKGYFFEPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWAND 419
Query: 420 TELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGI 479
+++GLA YVF+ N+ T+ VA+ LE G+V N + E I FGG+K+SGFG+E G+
Sbjct: 420 SDVGLAGYVFTNNLSTMIHVAKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGV 479
Query: 480 EDYTVIKTITIGNL 493
+++ V+K I + L
Sbjct: 480 QEFMVVKEINLKTL 493
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 396 bits (1018), Expect = e-110
Identities = 224/483 (46%), Positives = 309/483 (63%), Gaps = 13/483 (2%)
Query: 10 EFKNS-DLIRKGA--FVDGQWLETASET---FNVTDPATLEVIATLPDQSIEVIHEAIDS 63
+FK S L+ +GA ++ G+W TASET F+V +P EV+ + +++ +A+ S
Sbjct: 6 QFKRSYSLLPQGAQAYIGGKW--TASETGNSFDVLNPFNNEVVDRATNCTVKDAEKAVHS 63
Query: 64 AAEAFRLFKKT-TPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASY 122
A E F + T + K R L + ++++ +LA ++T E GK L+EA+GE++Y+A+Y
Sbjct: 64 ALEGFDKWAHTYSAKQRGAILHKWFEILVQRETELATLLTKEQGKPLAEARGEIQYSAAY 123
Query: 123 FEWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGC 182
F+WYA EA R+YG + + R+P+GV +I PWNFP+AMI RKA AAL+ GC
Sbjct: 124 FDWYAGEARRVYGQVVPSAVVNRLHLHTREPIGVVALIAPWNFPTAMIARKAAAALSVGC 183
Query: 183 TVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLT-ATRTPEFGLALCESPKVKKISFT 241
+ VVKP TPLSALALA AE+AG P GVFNV+ + T E LCES V ISFT
Sbjct: 184 SAVVKPSGDTPLSALALAQTAEEAGIPAGVFNVITADHSNTAEISKYLCESTDVSAISFT 243
Query: 242 GSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCA 301
GST VGK+L+ QSAST+K++ ELGGNAP+IVFDDADL+ AV T+ +KFR GQTCV A
Sbjct: 244 GSTPVGKLLLAQSASTVKRVCLELGGNAPLIVFDDADLDVAVNGTMATKFRCSGQTCVSA 303
Query: 302 NRIYVQRTIIDSFAEKLAKQVNE-FVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKG 360
NRIYV I D + KLA + E V+G GL+ KTT G L+N+ A+ K E + DAL KG
Sbjct: 304 NRIYVHEKIHDQYISKLAAAMKEKLVLGDGLNPKTTQGPLVNQKAVDKCELLLSDALGKG 363
Query: 361 AKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDT 420
++ ++ GG+ E G + Y PT++++V S + E FGP+ ++ F +EV+ AN+
Sbjct: 364 SE-LICGGKRGEHGTS-YEPTLITNVQSNTNIAHTEIFGPIASVQKFRDEQEVLEAANNC 421
Query: 421 ELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIE 480
+GLA YVF ++ + VA LE GMV N GL S FGGVKESG GREG GI+
Sbjct: 422 RVGLAGYVFGRDQSRLQRVARKLEVGMVGVNEGLISCAEAAFGGVKESGIGREGGAQGID 481
Query: 481 DYT 483
++T
Sbjct: 482 EFT 484
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 302 bits (773), Expect = 9e-82
Identities = 177/488 (36%), Positives = 271/488 (55%), Gaps = 8/488 (1%)
Query: 7 ITPEFKNSDLIRK--GAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSA 64
++ F N +++ G +++G+W ++A ET+ DP+ EVIA + + I A+ SA
Sbjct: 7 VSINFPNGKSVKQPIGLYINGEWHKSA-ETWETVDPSIEEVIAKVYLAGEKEIDYAVKSA 65
Query: 65 AEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKAL-SEAQGEVKYAASYF 123
EAF+ +KK + L L L ++ D LA I ++GK L S A+G+V +
Sbjct: 66 KEAFKTWKKVPGSEKGELLMKLAELTEKHADTLAAIEAMDSGKPLVSNARGDVDGTIALL 125
Query: 124 EWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCT 183
+ A A ++YG I P A+ R P+GVCG I PWN+P M K ALAAG
Sbjct: 126 RYCAGWADKIYGQVI-PTGPEKLAYAKRTPIGVCGQIVPWNYPLNMAGWKIAPALAAGNC 184
Query: 184 VVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGS 243
+++K TPLS L A L E+AGFPKGV N++ G + + P + KI+FTGS
Sbjct: 185 IIIKSAETTPLSLLYFATLVEEAGFPKGVVNIISGLGTVA--GSYMAKHPGIDKIAFTGS 242
Query: 244 TNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANR 303
T VG I+ + +AS +K ++ E GG +P +VF+DADL+QAV L GQ C +R
Sbjct: 243 TKVGVIVQQLAASNLKAVTLECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICTSNSR 302
Query: 304 IYVQRTIIDSFAEKLAKQV-NEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAK 362
IYVQ ++ D F E K V ++++G D T G ++N+ +++ +++ ++GAK
Sbjct: 303 IYVQDSVYDKFIELFKKHVIQDYIVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKEGAK 362
Query: 363 TVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTEL 422
V+ LP F +PT+ + + K+E FGP+ A+ F T +E + AN+T
Sbjct: 363 LVLGDEPLPLKQGYFISPTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAIEKANNTTY 422
Query: 423 GLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDY 482
GLA+ F+K+++ + V++ LE GMV N+ S+ PFGG+K SG G E +GIE Y
Sbjct: 423 GLAAMCFTKDLERAHRVSDELEAGMVFINSTENSDIQAPFGGIKMSGIGNELGSNGIEMY 482
Query: 483 TVIKTITI 490
T IK + I
Sbjct: 483 TQIKAVHI 490
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 295 bits (754), Expect = 1e-79
Identities = 169/476 (35%), Positives = 273/476 (56%), Gaps = 10/476 (2%)
Query: 22 FVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRST 81
F+DG++L +S + DP+T EV +P+ + I A+ +A EAF + +P+ RS
Sbjct: 13 FIDGKFLPCSSY-IDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSR 71
Query: 82 WLRNLYNLMMENVDDLAKIITWENGKALSEAQG-EVKYAASYFEWYAEEAVRMYGTTIQP 140
L + +L+ +++++ A+ + + GK L+ A+ ++ + F ++A ++ Q
Sbjct: 72 VLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQM 131
Query: 141 NNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALA 200
++ +TVR PVGV G+I PWN P ++T K A+AAG TV+ KP T ++A L
Sbjct: 132 DHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLC 191
Query: 201 HLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKK 260
L +KAG P GV N+V P G AL P+V ISFTGS + + + SA KK
Sbjct: 192 KLLDKAGVPPGVVNIVFGTG--PRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKK 249
Query: 261 LSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAK 320
LS ELGG P I+F+DA+L++ + T+ S F G+ C+C +RI+VQ++I F ++ +
Sbjct: 250 LSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVE 309
Query: 321 QVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGG----RLP--ELG 374
++ +G D + G LI++ ++KV ++VK AL +GA+ G LP
Sbjct: 310 ATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQA 369
Query: 375 PNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNID 434
F PTV++ + + +E FGP+ ++PFD+ EEV+ AN+ + GLA+ V+S N+
Sbjct: 370 GYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVG 429
Query: 435 TVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
V+ VA+ L++G+V N L E +PFGG+K SG GREG+ + +T IKTIT+
Sbjct: 430 RVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITV 485
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 290 bits (742), Expect = 3e-78
Identities = 177/486 (36%), Positives = 271/486 (55%), Gaps = 18/486 (3%)
Query: 15 DLIRKGAFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL--- 70
D++ G F++ +W ++ S + F +P T EVIA + E I A+ +A AF+L
Sbjct: 36 DILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSP 95
Query: 71 FKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQG-EVKYAASYFEWYAEE 129
+++ R L L +LM + LA + T +NGK S + ++ A ++A
Sbjct: 96 WRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGW 155
Query: 130 AVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPD 189
A + +G TI P +G +T +PVGVCG I PWNFP M+ K G ALA G T+V+KP
Sbjct: 156 ADKNHGKTI-PMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPA 214
Query: 190 SQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLA---LCESPKVKKISFTGSTNV 246
QT L+AL +A L ++AGFP+GV NVV P FG A L V K++FTGST+V
Sbjct: 215 EQTSLTALYIAQLVKEAGFPEGVVNVV------PGFGTAGAALANHCDVDKVAFTGSTDV 268
Query: 247 GKILMKQSAST-MKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIY 305
GK++ S +T +K+++ ELGG +P I+ D D++ AV F +GQ C +R +
Sbjct: 269 GKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTF 328
Query: 306 VQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVV 365
V+ I D F E+ A++ + +G+ D T G +NE ++K+ +K ++GAK +V
Sbjct: 329 VEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAK-LV 387
Query: 366 AGGRLPELGPNFYA-PTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGL 424
AGG PE P ++ PTV + V + ++E FGP+ LI F ++EV+ AN++E GL
Sbjct: 388 AGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGL 447
Query: 425 ASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTV 484
A+ VF+K++D + L G V NT PFGG K SG GRE + + +YT
Sbjct: 448 AAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTE 507
Query: 485 IKTITI 490
+K++ +
Sbjct: 508 VKSVIV 513
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 289 bits (740), Expect = 6e-78
Identities = 178/488 (36%), Positives = 268/488 (54%), Gaps = 14/488 (2%)
Query: 7 ITPEFK--NSDLIRKGAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSA 64
ITP K ++ L+ G FVD + +TF DP EVIA + + E ++ A+ +A
Sbjct: 19 ITPPVKVEHTQLLIGGRFVDA----VSGKTFPTLDPRNGEVIAQVSEGDAEDVNRAVAAA 74
Query: 65 AEAFRL--FKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSE-AQGEVKYAAS 121
+AF + K T RS L +L+ ++ D++A + TW+NGK + AQ EV A
Sbjct: 75 RKAFDEGPWPKMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAQIEVPMLAR 134
Query: 122 YFEWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAG 181
F +YA A +++G T+ P +G + T+ +P+GV G I PWNFP M++ K G ALA G
Sbjct: 135 VFRYYAGWADKIHGMTM-PGDGPHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACG 193
Query: 182 CTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFT 241
TVV+K QTPLSAL + L +AG P GV N+V T G A+ V K++FT
Sbjct: 194 NTVVLKTAEQTPLSALLVGKLLHEAGLPDGVVNIVSGFGATA--GAAIASHMDVDKVAFT 251
Query: 242 GSTNVGKILMK-QSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVC 300
GST+VGKI+++ S S +K ++ ELGG +P IV +DAD++QAV + F GQ C
Sbjct: 252 GSTDVGKIILELASKSNLKAVTLELGGKSPFIVCEDADVDQAVELAHFALFFNQGQCCCA 311
Query: 301 ANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKG 360
+R +V + D F EK + + +G S G ++ K+ ++K +E G
Sbjct: 312 GSRTFVHERVYDEFVEKAKARALKRNVGDPFKSGIEQGPQVDSEQFNKILKYIKHGVEAG 371
Query: 361 AKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDT 420
A G RL G + PTV S V ++ DE FGP+ ++ F ++EV+ AN++
Sbjct: 372 ATLQAGGDRLGSKG-YYIQPTVFSDVKDDMLIATDEIFGPVQTILKFKDLDEVIARANNS 430
Query: 421 ELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIE 480
GLA+ VF++N+DT + + AL G V N + +IPFGG K SG GRE ++ +
Sbjct: 431 RYGLAAGVFTQNLDTAHRLMRALRVGTVWINCFDVLDASIPFGGYKMSGIGREKGIYSLN 490
Query: 481 DYTVIKTI 488
+Y +K +
Sbjct: 491 NYLQVKAV 498
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 287 bits (735), Expect = 2e-77
Identities = 177/484 (36%), Positives = 267/484 (54%), Gaps = 10/484 (2%)
Query: 13 NSDLIRKGAFVDGQWLETASE-TFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL- 70
N D+ F++ +W + S+ TF +P T EVI + + + A+ +A EAFRL
Sbjct: 31 NPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLG 90
Query: 71 --FKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQG-EVKYAASYFEWYA 127
+++ R L L +L+ + LA + T +NGK E+ ++ + ++A
Sbjct: 91 SPWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFA 150
Query: 128 EEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVK 187
A + +G TI P +G + FT +PVGVCG I PWNFP M K ALA G TVV+K
Sbjct: 151 GWADKWHGKTI-PMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMK 209
Query: 188 PDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVG 247
QTPLSAL LA L ++AGFP GV N++ P G A+ + V K++FTGST VG
Sbjct: 210 VAEQTPLSALYLASLIKEAGFPPGVVNII--TGYGPTAGAAIAQHMDVDKVAFTGSTEVG 267
Query: 248 KILMKQSA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYV 306
++ K + S +K+++ ELGG +P IV DAD+E AV Q + F +GQ C +R +V
Sbjct: 268 HLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFV 327
Query: 307 QRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVA 366
+ +I + F E+ ++ + +G+ + T G +++ ++V +++ ++GAK +
Sbjct: 328 EESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCG 387
Query: 367 GGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLAS 426
G R E G F PTV V + K+E FGP+ L F +EEVV AN+T GLA+
Sbjct: 388 GERFGERG-FFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAA 446
Query: 427 YVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIK 486
VF++++D +AL+ G V NT C PFGG KESG GRE G++ YT +K
Sbjct: 447 AVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVK 506
Query: 487 TITI 490
T+TI
Sbjct: 507 TVTI 510
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 287 bits (734), Expect = 3e-77
Identities = 172/475 (36%), Positives = 266/475 (55%), Gaps = 10/475 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ +W + S +TF +P+T EVI + + E + +A+ +A AF+L +++
Sbjct: 40 FINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDAS 99
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKA-LSEAQGEVKYAASYFEWYAEEAVRMYGT 136
R L L +L+ + LA + T +NGK + ++ +YA A + +G
Sbjct: 100 HRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGK 159
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
TI P +G ++T +PVGVCG I PWNFP M K G ALA G VV+K QTPL+A
Sbjct: 160 TI-PIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 218
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKIL-MKQSA 255
L +A+L ++AGFP GV N+V P G A+ V K++FTGST +G+++ + +
Sbjct: 219 LYVANLIKEAGFPPGVVNIV--PGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGS 276
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFA 315
S +K+++ ELGG +P I+ DAD++ AV Q + F GQ C +R +VQ I D F
Sbjct: 277 SNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFV 336
Query: 316 EKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGP 375
E+ + V+G+ DSKT G ++E KK+ ++ ++GAK + GG + G
Sbjct: 337 ERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRG- 395
Query: 376 NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDT 435
F PTV V + K+E FGP+ ++ F T+EEVVG AN++ GLA+ VF+K++D
Sbjct: 396 YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDK 455
Query: 436 VYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
+++AL+ G V N PFGG K SG GRE +G++ YT +KT+T+
Sbjct: 456 ANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTV 510
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 286 bits (733), Expect = 4e-77
Identities = 170/476 (35%), Positives = 262/476 (54%), Gaps = 9/476 (1%)
Query: 20 GAFVDGQWLETA-SETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTT 75
G F++ Q +++ V P+T ++I + D E + A+ A AF+ ++K +
Sbjct: 24 GLFINNQHVDSVHGGRVKVYSPSTEKLICEVADADEEDVDIAVKVARAAFQTDAPWRKFS 83
Query: 76 PKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYG 135
R L L + + +N++ LA I T +NGK+++ A+G+V+ AA F +Y A + YG
Sbjct: 84 SAQRGRCLSRLADCIEQNLEYLASIETLDNGKSITLARGDVQAAADCFRYYGGWADKDYG 143
Query: 136 TTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLS 195
TI+ + A+T +P+GVCG I PWNFP M K A+A G T+++K TPLS
Sbjct: 144 QTIETDI-KRFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACGNTIILKTAELTPLS 202
Query: 196 ALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSA 255
AL L + GFP GV NV+ R G A+ + K++FTGST VG+++M+ +A
Sbjct: 203 ALCLTKFVPECGFPPGVINVLSGDGR--RCGNAISSHMDIDKVAFTGSTGVGRMVMRAAA 260
Query: 256 ST-MKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSF 314
S+ +KK++ ELGG +P IVF+DADL+ A T F GQ C +R+YVQ + D F
Sbjct: 261 SSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCAGSRVYVQEDVYDEF 320
Query: 315 AEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELG 374
+++ + +G T G +++ +++ ++++ + GAK + G R LG
Sbjct: 321 IKRMVAKAKTLKVGDPFAEDTFQGAQVSKQQYERIVSYIESGIAHGAKLEIGGKRHGNLG 380
Query: 375 PNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNID 434
F PT+LS+V V K+E FGP+ A+I F T+EE + N++ GLA+ V + NI
Sbjct: 381 -YFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNSTYGLAAGVHTNNIT 439
Query: 435 TVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
V+ ALE G V N IPFGG KESG GRE +G+ +YT K + I
Sbjct: 440 NAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRELGSYGLTNYTQTKAVHI 495
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 285 bits (728), Expect = 1e-76
Identities = 169/474 (35%), Positives = 266/474 (55%), Gaps = 8/474 (1%)
Query: 20 GAFVDGQWLETASE-TFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL-FKKTTPK 77
G F++G+++ + + TF+V +P+ E I T+ + + EA+ +A +AF + P+
Sbjct: 45 GLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEPE 104
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTT 137
R+ L NL +L+ ++ + LA I + +NGK+L A+G+V + Y A ++YG
Sbjct: 105 VRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDVALVSKYLRSCGGWADKIYGNV 164
Query: 138 IQPNNGSNR-AFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
I + G N +++++P+GVCG I PWNFP M + K G ALA G TVV+KP TPLSA
Sbjct: 165 I--DTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSA 222
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSAS 256
L + L ++AG P GV N++ + R G L P VKKI+FTGST G+ +MK +A
Sbjct: 223 LFASQLCQEAGIPAGVVNILPGSGRV--VGERLSAHPDVKKIAFTGSTATGRHIMKVAAD 280
Query: 257 TMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAE 316
T+KK++ ELGG +P IVF DADL++AV F G+ C +RIY+Q T+ + +
Sbjct: 281 TVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQ 340
Query: 317 KLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN 376
KL +G D + G ++ + K+ +V A +GA+ V G R G
Sbjct: 341 KLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSKG-Y 399
Query: 377 FYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTV 436
F PTV + V + K+E FGP+ + F T++EV+ AND++ GLA+ + + +I+
Sbjct: 400 FVKPTVFADVKGDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKA 459
Query: 437 YTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
V++ ++ G V NT +PFGG +SG GRE + +YT K++ I
Sbjct: 460 VDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRI 513
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 285 bits (728), Expect = 1e-76
Identities = 177/491 (36%), Positives = 270/491 (54%), Gaps = 13/491 (2%)
Query: 10 EFKNSDLIRKGAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFR 69
+ ++ L+ G FVD + +TF DP T EVIA + + E I+ A+ +A AF
Sbjct: 54 QVSHTQLLINGNFVDS----ASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVKAARTAFD 109
Query: 70 L--FKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEA-QGEVKYAASYFEWY 126
+ K + RS L +L+ ++ ++LA + TW+NGK ++ E+ A F +Y
Sbjct: 110 EGPWPKMSAYERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYY 169
Query: 127 AEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVV 186
A A +++G TI P +G+ + T+ +P+GV G I PWNFP M K G ALA G T+V+
Sbjct: 170 AGWADKIHGLTI-PADGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVL 228
Query: 187 KPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNV 246
K QTPL+A L +AG P GV N+V T G AL V K++FTGST+
Sbjct: 229 KTAEQTPLTAFYAGKLFLEAGLPPGVLNIVSGFGATA--GAALASHMDVDKLAFTGSTDT 286
Query: 247 GKILMKQSA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIY 305
GK+++ +A S +K ++ ELGG +P IVF+DAD+++AV + F GQ C +R +
Sbjct: 287 GKVILGLAANSNLKPVTLELGGKSPFIVFEDADIDKAVELAHFALFFNQGQCCCAGSRTF 346
Query: 306 VQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVV 365
V + D F EK + + V+G G I+ +KV ++K +E A
Sbjct: 347 VHEKVYDEFVEKSKARALKRVVGDPFRKGIEQGPQIDLKQFEKVMKYIKSGIESNATLEC 406
Query: 366 AGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLA 425
G ++ + G F PTV S+V ++ +DE FGP+ +++ F ++EV+ AN+T+ GLA
Sbjct: 407 GGDQIGDKG-YFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRANETKYGLA 465
Query: 426 SYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVI 485
+ VF+KN+DT V+ AL+ G V N + IPFGG K SG GRE ++ + +Y I
Sbjct: 466 AGVFTKNLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQI 525
Query: 486 K-TITIGNLPA 495
K +T N PA
Sbjct: 526 KAVVTALNKPA 536
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 284 bits (726), Expect = 2e-76
Identities = 173/465 (37%), Positives = 257/465 (55%), Gaps = 11/465 (2%)
Query: 32 SETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMM 91
S T +PAT VIAT + ++ A+ +A AF+++ + + R L ++
Sbjct: 25 SGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIR 84
Query: 92 ENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQPNNGSNRAFTVR 151
E D++A + NGK++ EA+ ++ + E+YA A M G IQ GS +T R
Sbjct: 85 EREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSF-GYTRR 143
Query: 152 QPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKG 211
+P+GVC I WN+P + + K+ ALA G +V KP TP+SAL LA + +AG P G
Sbjct: 144 EPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPG 203
Query: 212 VFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPV 271
+FNVV T +F LC+ P V K+SFTGS G +M+ SA +K ++ ELGG +P+
Sbjct: 204 LFNVVQGGAATGQF---LCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPL 260
Query: 272 IVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGL 331
I+F D D+ AV +++ F GQ C R++VQ+ I+D F E++ KQ IG L
Sbjct: 261 IIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPL 320
Query: 332 DSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRL-----PELGPNFY-APTVLSH 385
T G LIN +++V VK A E+GAK V+ GG + P+L +Y P VL++
Sbjct: 321 LEDTRMGPLINRPHLERVLGFVKVAKEQGAK-VLCGGDIYVPEDPKLKDGYYMRPCVLTN 379
Query: 386 VPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALET 445
K+E FGP+ +++ FDT EV+ ANDT GLA+ VF+++I + V L+
Sbjct: 380 CRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQA 439
Query: 446 GMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
G N S +PFGG K+SGFGRE IE Y+ +KT+ +
Sbjct: 440 GTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCV 484
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 282 bits (721), Expect = 9e-76
Identities = 169/474 (35%), Positives = 268/474 (55%), Gaps = 10/474 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ +++++ S +TF +PAT + I + + I A+ +A +AF ++K +P
Sbjct: 188 FINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPL 247
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTT 137
R+ + L LM + LA + T +NGK +EA +V Y+ ++YA + +G T
Sbjct: 248 QRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDT 307
Query: 138 IQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSAL 197
I G + T ++PVGV G I PWN+P M+ K G ALA GCT+++KP QTPL+AL
Sbjct: 308 IPA--GGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTAL 365
Query: 198 ALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSA-S 256
+A LA++AGFP GV NVV P G A+ P + K++FTGS +G+I+M+ +A S
Sbjct: 366 HMAALAKEAGFPAGVINVV--NGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATS 423
Query: 257 TMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAE 316
+K++S ELGG +PV+VFDDAD++ AV T + F GQ+C +R YV I D F
Sbjct: 424 NLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVA 483
Query: 317 KLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN 376
K A + +G+ + G I+++ + KV +++ ++GAK G R+ +G
Sbjct: 484 KAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVG-F 542
Query: 377 FYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTV 436
F PTV S V + ++E FGP+ ++ F ++EE++ AN+ + GLA+ V + +I+
Sbjct: 543 FVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKA 602
Query: 437 YTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
A ++ G V N + PFGG K SG GRE G+++Y KTIT+
Sbjct: 603 LKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITM 656
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 280 bits (717), Expect = 3e-75
Identities = 176/492 (35%), Positives = 267/492 (53%), Gaps = 10/492 (2%)
Query: 5 TGITPEFKNSDLIRKGAFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDS 63
+G+ P N G F++ +++ S +TF +PA +V+A + + ++ A+ +
Sbjct: 16 SGVPPGLSNMKPQYTGIFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKA 75
Query: 64 AAEAFRL---FKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEA-QGEVKYA 119
A AFR+ +++ R L L +LM + LA + + +NGK + A ++ +
Sbjct: 76 AQNAFRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLS 135
Query: 120 ASYFEWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALA 179
A + +G TI P G +T +PVGVCG I PWNFP M K G ALA
Sbjct: 136 IKTLRLLRRMADKNHGKTI-PIEGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALA 194
Query: 180 AGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKIS 239
G TVV+K QTPLSAL +A L ++AGFP GV N++ T G A+ V K++
Sbjct: 195 MGNTVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTA--GQAISSHMDVDKVA 252
Query: 240 FTGSTNVGKILMKQSA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTC 298
FTGST VG+++MK +A S +KK++ ELGG +P I+F DADL +V Q F GQ C
Sbjct: 253 FTGSTEVGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCC 312
Query: 299 VCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALE 358
+R +V+ I D F + + + VIG D KTT G ++ ++ + ++ +
Sbjct: 313 CAGSRTFVEGKIYDDFVARSKELAEKAVIGDPFDLKTTQGPQVDGKQVETILKYIAAGKK 372
Query: 359 KGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYAN 418
GA+ V G + + G +F PT+ ++V + ++E FGP+ +I FDTMEE+V AN
Sbjct: 373 DGAQLVTGGAKHGDQG-HFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKAN 431
Query: 419 DTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHG 478
+T GLA+ V +K+ID +A A G V N + PFGG K+SG GRE +G
Sbjct: 432 NTIYGLAAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYG 491
Query: 479 IEDYTVIKTITI 490
+E YT +KT+TI
Sbjct: 492 LEAYTEVKTVTI 503
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 280 bits (715), Expect = 5e-75
Identities = 172/475 (36%), Positives = 273/475 (57%), Gaps = 10/475 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ ++++ S +TF +PA +++A + + + + + A+++A +AF++ +++
Sbjct: 60 FINNEFVDAKSGKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDAS 119
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQG-EVKYAASYFEWYAEEAVRMYGT 136
R L L +LM + LA + + +NGK EA ++ + F +YA A + +G
Sbjct: 120 HRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNHGK 179
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
TI P G +T +PVGVCG I PWNFP M K ALA G TVV+K +TPLSA
Sbjct: 180 TI-PVGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSA 238
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSA- 255
L +A L ++A FP+GV N++ R + G A+ V K++FTGST VGK +MK +A
Sbjct: 239 LHVASLIKEAQFPEGVVNII--PGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAE 296
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFA 315
S +KK++ ELGG +P IVF DADLE+AV Q+ + F GQ C +R +V+ I D F
Sbjct: 297 SNVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFV 356
Query: 316 EKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGP 375
K + V + VIG D TT G I+E+ ++ + +++ ++GA+ V G + + G
Sbjct: 357 AKAKELVEKTVIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGDQG- 415
Query: 376 NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDT 435
F PT+ ++V + ++E FGP+ +I FD+MEE++ AN+T GLA+ V + +++
Sbjct: 416 YFVKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDLNK 475
Query: 436 VYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
VA + G V N + PFGG K+SG GRE +G+ YT +KT+TI
Sbjct: 476 ALQVANTIRAGSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTVTI 530
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 279 bits (714), Expect = 6e-75
Identities = 175/479 (36%), Positives = 271/479 (56%), Gaps = 16/479 (3%)
Query: 20 GAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFR--LFKKTTPK 77
G FVD + +T SET N TD + VI + + + +A+ +A +AF + K + +
Sbjct: 428 GEFVDAEGAKT-SETINPTDGS---VICQVSLAQVTDVDKAVAAAKDAFENGRWGKISAR 483
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEA-QGEVKYAASYFEWYAEEAVRMYGT 136
R + L +LM ++ ++LA I + G + A + V + F ++A ++ G+
Sbjct: 484 DRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGS 543
Query: 137 TIQPNNGS---NRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTP 193
TI N N T ++PVGVCGII PWN+P M++ K A LAAG TVV+KP TP
Sbjct: 544 TIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTP 603
Query: 194 LSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQ 253
L+AL A L KAG PKGV NV+ + G L + P V+KI FTGST VGK +MK
Sbjct: 604 LTALKFAELTLKAGIPKGVVNVLPGSGSL--VGQRLSDHPDVRKIGFTGSTEVGKHIMKS 661
Query: 254 SA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIID 312
A S +KK+S ELGG +P+I+F D DL +AV + S F G+ C+ A R++V+ +I D
Sbjct: 662 CAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHD 721
Query: 313 SFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPE 372
F ++ ++V + +G+ LD T HG + + K+ + + +++GA V G ++P
Sbjct: 722 EFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 373 LGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPF--DTMEEVVGYANDTELGLASYVFS 430
G F+ PTV + V + K+E+FGP+ + F ++ V+ AN TE GLAS VF+
Sbjct: 782 PG-FFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFT 840
Query: 431 KNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTIT 489
++I+ V++ L+ G V NT ++ PFGG K+SGFG++ + +Y +KT+T
Sbjct: 841 RDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVT 899
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 278 bits (711), Expect = 1e-74
Identities = 169/475 (35%), Positives = 262/475 (54%), Gaps = 10/475 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ +W + S +TF +P+T EVI + + E + +A + AF+L +++
Sbjct: 39 FINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAREGRPGAFQLGSPWRRMDAS 98
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKA-LSEAQGEVKYAASYFEWYAEEAVRMYGT 136
L L +L+ + LA + T +NGK + ++ +YA A + +G
Sbjct: 99 HSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGK 158
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
TI P +G ++T +PVGVCG I PWNFP M K G ALA G VV+K QTPL+A
Sbjct: 159 TI-PIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 217
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKIL-MKQSA 255
L +A+L ++AGFP GV N+V P G A+ V K++FTGST +G+++ + +
Sbjct: 218 LYVANLIKEAGFPPGVVNIV--PGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGS 275
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFA 315
S +K+++ ELGG +P I+ DAD++ AV Q + F GQ C +R +VQ I D F
Sbjct: 276 SNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFV 335
Query: 316 EKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGP 375
+ + V+G+ DSKT G ++E KK+ ++ ++GAK + GG + G
Sbjct: 336 VRSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRG- 394
Query: 376 NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDT 435
F PTV V + K+E FGP+ ++ F T+EEVVG AN++ GLA+ VF+K++D
Sbjct: 395 YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDK 454
Query: 436 VYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
+++AL+ G V N PFGG K SG GRE +G++ YT +KT+T+
Sbjct: 455 ANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTV 509
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 277 bits (708), Expect = 3e-74
Identities = 175/479 (36%), Positives = 269/479 (55%), Gaps = 16/479 (3%)
Query: 20 GAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFR--LFKKTTPK 77
G FVD + +T SET N TD + VI + + + +A+ +A AF + K + +
Sbjct: 428 GEFVDAEGAKT-SETINPTDGS---VICQVSLAQVTDVDKAVAAAKGAFENGRWGKISAR 483
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEA-QGEVKYAASYFEWYAEEAVRMYGT 136
R + L +LM ++ ++LA I + G + A + V + F ++A ++ G+
Sbjct: 484 DRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGS 543
Query: 137 TIQPNNGS---NRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTP 193
TI N N T ++PVGVCGII PWN+P M++ K A LAAG TVV+KP TP
Sbjct: 544 TIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTP 603
Query: 194 LSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQ 253
L+AL A L KAG PKGV NV+ + G L + P V+KI FTGST VGK +MK
Sbjct: 604 LTALKFAELTLKAGIPKGVVNVLPGSGSL--VGQRLSDHPDVRKIGFTGSTEVGKHIMKS 661
Query: 254 SA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIID 312
A S +KK+S ELGG +P I+F D DL +AV + S F G+ C+ A R++V+ +I D
Sbjct: 662 CAISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAAGRLFVEDSIHD 721
Query: 313 SFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPE 372
F ++ ++V + +G+ LD T HG + + K+ + + +++GA V G ++P
Sbjct: 722 EFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 373 LGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPF--DTMEEVVGYANDTELGLASYVFS 430
G F+ PTV + V + K+E+FGP+ + F ++ V+ AN TE GLAS VF+
Sbjct: 782 PG-FFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFT 840
Query: 431 KNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTIT 489
++I+ V++ L+ G V NT ++ PFGG K+SGFG++ + +Y +KT+T
Sbjct: 841 RDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVT 899
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 273 bits (698), Expect = 4e-73
Identities = 163/472 (34%), Positives = 256/472 (53%), Gaps = 7/472 (1%)
Query: 20 GAFVDGQWLETA-SETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFR--LFKKTTP 76
G F++ +++ + ++TF V +P+T E I + + + + EA+ +A AF + P
Sbjct: 46 GLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDP 105
Query: 77 KTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGT 136
R L L L+ ++ D +A I T +NGKA+S ++G+V +Y + A A ++ G
Sbjct: 106 IDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGR 165
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
I ++ ++T RQP+GVCG I PWNFP M K AL G TVV+K TPLSA
Sbjct: 166 MIDTGR-THFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSA 224
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSAS 256
L ++ +AG P GV N+V + G A+ PK+KK++FTGST G+ + + +A+
Sbjct: 225 LYVSKYIPQAGIPPGVINIVSGFGKI--VGEAITNHPKIKKVAFTGSTATGRHIYQSAAA 282
Query: 257 TMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAE 316
+KK++ ELGG +P IVF DA+L++AV IL + G+ C +R+YV+ +I D F E
Sbjct: 283 GLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIE 342
Query: 317 KLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN 376
+ +G D T G ++ + K+ +V +GA + G RL G
Sbjct: 343 EFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKG-Y 401
Query: 377 FYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTV 436
F PTV V + K+E FGP+ + F + +EV+ AND+E GLA+ + + NI+T
Sbjct: 402 FIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTA 461
Query: 437 YTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTI 488
VA+ + G V NT +PFGG SG GRE S+ +++Y +K +
Sbjct: 462 LKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAV 513
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 272 bits (695), Expect = 1e-72
Identities = 162/462 (35%), Positives = 268/462 (57%), Gaps = 13/462 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL--FKKTTPKT 78
F++GQ+ + +T++ +P I + S+ + +A+ +A +AF + + +
Sbjct: 446 FINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARE 505
Query: 79 RSTWLRNLYNLMMENVDDLAKIITWENGKALSEA-QGEVKYAASYFEWYAEEAVRMYGTT 137
R + L +L+ EN ++LA I ++G + A + + + F ++A ++ G+T
Sbjct: 506 RGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGST 565
Query: 138 IQPNNGS---NRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPL 194
I N N FT ++P+GVC II PWN+P M+ K+ A LAAG T+V+KP TPL
Sbjct: 566 IPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPL 625
Query: 195 SALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQS 254
+AL A L+ KAGFPKGV N++ + G L E P ++K+ FTGST +GK +MK
Sbjct: 626 TALKFAELSVKAGFPKGVINIIPGSGGIA--GQRLSEHPDIRKLGFTGSTPIGKQIMKSC 683
Query: 255 A-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDS 313
A S +KK+S ELGG +P+I+F+D +L++AV + + F G+ C+ A R++V+ +I D
Sbjct: 684 AVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDE 743
Query: 314 FAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPEL 373
F ++ +++ + IG LD T HG ++ ++K+ + + +++GA T+V GGR +
Sbjct: 744 FVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGA-TLVYGGRQVQR 802
Query: 374 GPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDT--MEEVVGYANDTELGLASYVFSK 431
F PTV + V + K+E+FGP+ + F ++ V+ AN TE GLAS VF++
Sbjct: 803 PGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTR 862
Query: 432 NIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGRE 473
+I+ V+E LE G V NT ++ PFGGVK+SGFG++
Sbjct: 863 DINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKD 904
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 271 bits (693), Expect = 2e-72
Identities = 164/483 (33%), Positives = 258/483 (52%), Gaps = 14/483 (2%)
Query: 18 RKGAFVDGQWLETA-SETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAF-----RLF 71
R+ F+ GQW E +T V +PAT ++I +P + E + A+++A +AF + +
Sbjct: 7 RRQLFIGGQWTEPVLRKTLPVVNPATEDIIGYIPAATSEDVELAVEAARKAFTRNNGKDW 66
Query: 72 KKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAV 131
+ T R+ +LR + ++E +LA + + GK L EA ++ A FE+YA+ A
Sbjct: 67 ARATGAVRAKYLRAIAAKVIERKSELANLEAIDCGKPLDEAAWDMDDVAGCFEYYADLAE 126
Query: 132 RMYGTTIQPNN---GSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKP 188
+ P + + + + +++P+GV G+I PWN+P M K +LAAGCT ++KP
Sbjct: 127 GLDAKQKTPLSLPMDTFKGYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKP 186
Query: 189 DSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGK 248
L+ L LA + + G P GV N+ LT T E G L P V KI FTGST G
Sbjct: 187 SELASLTCLELADICREVGLPPGVLNI-LTGLGT-EAGAPLASHPHVDKIVFTGSTTTGS 244
Query: 249 ILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQR 308
+M +A +K +S ELGG +P+IVFDD D+++AV T+ F GQ C +R+ V
Sbjct: 245 SIMTSAAKLVKPVSLELGGKSPIIVFDDVDIDKAVEWTMFGCFWTNGQICSATSRLLVHE 304
Query: 309 TIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGG 368
I D F +KL K I + G ++++ ++V V +A +GA TV+ GG
Sbjct: 305 RIADEFLDKLVKWTKNIKISDPFEEGCRLGPVVSKGQYERVLKFVSNARNEGA-TVLCGG 363
Query: 369 RLPE--LGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLAS 426
PE F P ++S+V ++ + ++E FGP + F T +E + AND++ GLA
Sbjct: 364 VRPEHLKKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQYGLAG 423
Query: 427 YVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIK 486
V S +++ V++A + G+V N C P+GG K SGFGRE G+E+Y +K
Sbjct: 424 AVLSNDLERCDRVSKAFQAGIVWVNCSQPCFCQAPWGGTKRSGFGRELGEWGLENYLSVK 483
Query: 487 TIT 489
+T
Sbjct: 484 QVT 486
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 270 bits (690), Expect = 4e-72
Identities = 166/475 (34%), Positives = 265/475 (54%), Gaps = 10/475 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ +W ++ S + F V +PAT E + + + E + +A+ +A +AF++ ++
Sbjct: 24 FINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDAS 83
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQ-GEVKYAASYFEWYAEEAVRMYGT 136
R L L +L+ + LA + + GK S A ++ + A A ++ G
Sbjct: 84 ERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGWADKIQGR 143
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
TI P +G+ +T +P+GVCG I PWNFP M+ K G AL+ G TVVVKP QTPL+A
Sbjct: 144 TI-PIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTA 202
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSA- 255
L +A L ++AGFP GV N+V P G A+ + K++FTGST VGK++ + +
Sbjct: 203 LHVASLIKEAGFPPGVVNIV--PGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGK 260
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFA 315
S +K+++ ELGG +P IV DADL+ AV F GQ C+ A+RI+V+ +I D F
Sbjct: 261 SNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFV 320
Query: 316 EKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGP 375
+ ++ ++++G+ L T G I++ K+ ++ ++GAK GG G
Sbjct: 321 RRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKG- 379
Query: 376 NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDT 435
F PTV S+V + K+E FGP+ ++ F ++++V+ AN+T GL++ VF+K+ID
Sbjct: 380 YFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDK 439
Query: 436 VYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
T++ AL+ G V N PFGG K SG GRE +G +YT +KT+T+
Sbjct: 440 AITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTV 494
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 270 bits (690), Expect = 4e-72
Identities = 166/475 (34%), Positives = 265/475 (54%), Gaps = 10/475 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ +W ++ S + F V +PAT E + + + E + +A+ +A +AF++ ++
Sbjct: 24 FINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDAS 83
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQ-GEVKYAASYFEWYAEEAVRMYGT 136
R L L +L+ + LA + + GK S A ++ + A A ++ G
Sbjct: 84 ERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGR 143
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
TI P +G+ +T +P+GVCG I PWNFP M+ K G AL+ G TVVVKP QTPL+A
Sbjct: 144 TI-PIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTA 202
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSA- 255
L +A L ++AGFP GV N+V P G A+ + K++FTGST VGK++ + +
Sbjct: 203 LHVASLIKEAGFPPGVVNIV--PGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGK 260
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFA 315
S +K+++ ELGG +P IV DADL+ AV F GQ C+ A+RI+V+ +I D F
Sbjct: 261 SNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFV 320
Query: 316 EKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGP 375
+ ++ ++++G+ L T G I++ K+ ++ ++GAK GG G
Sbjct: 321 RRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKG- 379
Query: 376 NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDT 435
F PTV S+V + K+E FGP+ ++ F ++++V+ AN+T GL++ VF+K+ID
Sbjct: 380 YFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDK 439
Query: 436 VYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
T++ AL+ G V N PFGG K SG GRE +G +YT +KT+T+
Sbjct: 440 AITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTV 494
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 268 bits (684), Expect = 2e-71
Identities = 168/476 (35%), Positives = 256/476 (53%), Gaps = 11/476 (2%)
Query: 22 FVDGQW---LETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFR--LFKKTTP 76
F+DG++ +E A++ + +PAT E+I T + S + + A+++A FR ++ K
Sbjct: 24 FIDGKFVSPIEPAAKPIPLINPATEEIIGTCANASAKDVDSAVENAYNTFRSGIWAKWPG 83
Query: 77 KTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGT 136
K R LR + +M E + LA I T GK A ++ A FE+YAE A
Sbjct: 84 KQRGLVLRKIAKMMREKRELLAGIDTINCGKPTPYALFDIDSCADMFEYYAEVA-ETDNP 142
Query: 137 TIQ---PNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTP 193
T++ PNN AF R P GV G+I PWNFP M K A+A+G VV+KP P
Sbjct: 143 TVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSELAP 202
Query: 194 LSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQ 253
S L A + ++AG P GV NV++ + + E G AL PK+ ++FTGS GK +M
Sbjct: 203 WSCLEFALICKEAGLPDGVLNVIIGSGK--ESGAALSCHPKIAYLAFTGSLATGKKIMHA 260
Query: 254 SASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDS 313
+A + L+ ELGG +P+I+ +DADL A+ + F G+ C A+R+ V ++ D
Sbjct: 261 AAENIVPLTLELGGKSPLIICEDADLSLAIPSAAFAIFFNQGEACTAASRLIVHESVADE 320
Query: 314 FAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPEL 373
L + N+ +IG+GLD + T G ++++ +K+ ++++ A+ +G K VV G E
Sbjct: 321 VLGGLVSEANKLIIGNGLDPQVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGLPRSEQ 380
Query: 374 GPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNI 433
F PTV ++V + + ++E FGP+ A+ F T EE + AND+E GL S VFS N
Sbjct: 381 KGYFIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALELANDSEYGLGSGVFSTNP 440
Query: 434 DTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTIT 489
T+ + +E GM S N +P+ G K SG G S HG +Y +K IT
Sbjct: 441 KTLEFFSNNIEAGMCSLNNYHVVTHELPWIGWKHSGLGVGLSKHGYNEYMRLKQIT 496
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 268 bits (684), Expect = 2e-71
Identities = 168/479 (35%), Positives = 257/479 (53%), Gaps = 18/479 (3%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ +W + S F V +PAT E + + + I +A+ +A AF L +++
Sbjct: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEA-----QGEVKYAASYFEWYAEEAVR 132
R L L +L+ + LA + + GK +A QG +K F +YA A +
Sbjct: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKT----FRYYAGWADK 156
Query: 133 MYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQT 192
++G TI P +G FT +P+GVCG I PWNFP M K AL G TVV+KP QT
Sbjct: 157 IHGMTI-PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215
Query: 193 PLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMK 252
PLSAL + L ++AGFP GV N++ P G A+ + KI+FTGST VGK++ +
Sbjct: 216 PLSALYMGALIKEAGFPPGVINIL--PGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273
Query: 253 QSA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTII 311
+ S +K+++ ELGG +P I+F DADL+ AV Q F GQ C +RI+V+ +I
Sbjct: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333
Query: 312 DSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLP 371
+ F + ++ ++G D T G I++ K+ ++ + +GAK G L
Sbjct: 334 EEFVRRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393
Query: 372 ELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSK 431
G F PTV S+V + K+E FGP+ ++ F TM+EV+ AN+++ GL + VF+
Sbjct: 394 RKG-FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN 452
Query: 432 NIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
+I+ TV+ A++ G V N PFGG K SG GRE G+ +Y+ +KT+T+
Sbjct: 453 DINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 267 bits (683), Expect = 2e-71
Identities = 166/477 (34%), Positives = 261/477 (53%), Gaps = 14/477 (2%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL---FKKTTPK 77
F++ +W E+ S + F +P+T E I + + + +A+++A AF+ +++
Sbjct: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94
Query: 78 TRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQG-EVKYAASYFEWYAEEAVRMYGT 136
+R L L +L+ + LA + T + GK A +++ ++A A ++ G
Sbjct: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
TI P + + FT +P+GVCG I PWNFP M+ K AL G T+V+KP QTPL+A
Sbjct: 155 TI-PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA 213
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQ-SA 255
L L L ++AGFP GV N+V P G A+ P++ KI+FTGST VGK++ + S
Sbjct: 214 LYLGSLIKEAGFPPGVVNIV--PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFA 315
S +K+++ ELGG P IV DADL+ AV F GQ C A+R++V+ + F
Sbjct: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331
Query: 316 EKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGP 375
+ + + +G D KT G I++ K+ ++ ++GAK G + + G
Sbjct: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391
Query: 376 NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDT 435
F PTV S V + K+E FGP+ ++ F ++EEV+ AN T+ GL + VF+KN+D
Sbjct: 392 -FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450
Query: 436 VYTVAEALETGMV--SCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
+A ALE+G V +C L+++ PFGG K SG GRE + + +YT +KT+TI
Sbjct: 451 ALKLASALESGTVWINCYNALYAQA--PFGGFKMSGNGRELGEYALAEYTEVKTVTI 505
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 267 bits (683), Expect = 2e-71
Identities = 159/468 (33%), Positives = 263/468 (55%), Gaps = 11/468 (2%)
Query: 31 ASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLM 90
++ETF+V +P +V+A P + +++ + + +AA+A + +TT R L + +L+
Sbjct: 100 STETFDVIEPRIGQVVAKCPKATADIVDQYVKAAADAQSAWGETTALDRGKVLHKVADLI 159
Query: 91 MENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVR-MYGTTIQ-PNNGSNR-A 147
E+ +++A NGK + EA+ ++ +A F+++ A + G +++ P S R A
Sbjct: 160 REHAEEIAIWEVKTNGKPIYEARCDIASSADTFDFFGGIATAVLQGDSLELPGGPSQRIA 219
Query: 148 FTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAG 207
+T R+P GV G I WN+P K ALAAG VV KP P S + L + AG
Sbjct: 220 YTRREPYGVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPASPVLLGEILTAAG 279
Query: 208 FPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSAS-TMKKLSFELG 266
PKGV+NV+ E G+ALCE V K+SFTGS G+ + +Q+A+ +K ++ ELG
Sbjct: 280 VPKGVYNVI---QGEQEAGVALCEHNLVAKVSFTGSVASGEAVQRQAATKNVKPVTLELG 336
Query: 267 GNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFV 326
G + +I+FDD+D++ AV +L+ F GQ C A R++VQ+ I+ SF E + ++ N+ +
Sbjct: 337 GKSEIIIFDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTEAIVQEANDKL 396
Query: 327 -IGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN---FYAPTV 382
+G L T G INE ++++ +V+ A ++G + G R+ G ++ P +
Sbjct: 397 KVGDPLLEDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRVHPTGVEGGAYFEPAI 456
Query: 383 LSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEA 442
++ + A ++E FG + ++PF+T EEV+ AN+T GLA+ VFS N+ + VA
Sbjct: 457 ITGLSDEARAVREEIFGAVMLILPFETEEEVIARANNTTYGLAAGVFSGNLARGHRVAAR 516
Query: 443 LETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
L+ G V NT +E +PFGG K SG GRE + + +T K I +
Sbjct: 517 LQAGTVFINTYNDTEVNVPFGGFKNSGHGRENCIDTLRAHTQTKAIYV 564
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 264 bits (674), Expect = 3e-70
Identities = 164/476 (34%), Positives = 253/476 (52%), Gaps = 9/476 (1%)
Query: 20 GAFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTT--P 76
G F++ ++++ +T+ V DP+T + + + E + AI+ A AF + T P
Sbjct: 27 GLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDP 86
Query: 77 KTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGT 136
+ R L L + + +D ++ I +NGK L+ A+G+V A + A A ++ G
Sbjct: 87 RERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVNGR 146
Query: 137 TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSA 196
TI +G FT +P+GVCG I PWNFP M+ K ALA G ++KP + TPL+A
Sbjct: 147 TINTGDGYMN-FTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNA 205
Query: 197 LALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGK-ILMKQSA 255
L A L +K G P GV N+V RT G AL P+++K++FTGST VGK + + S
Sbjct: 206 LYFASLCKKVGIPAGVVNIVPGPGRT--VGAALTNDPRIRKLAFTGSTEVGKSVAVDSSE 263
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSF- 314
S +KK++ ELGG + +VFDDA++++ + + F+ GQ C +RIYVQ I D
Sbjct: 264 SNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELL 323
Query: 315 AEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELG 374
A A E +G+ D G + N + ++ ++GAK + G ++ + G
Sbjct: 324 AAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKG 383
Query: 375 PNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNID 434
F PTV V + K+E FGP+ + F T+EE V AN +E GL S + ++++
Sbjct: 384 -YFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLS 442
Query: 435 TVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
T VA+ L+ G V NT + +PFGGVK+SG+GRE YT +K + I
Sbjct: 443 TGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRI 498
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 257 bits (656), Expect = 3e-68
Identities = 164/482 (34%), Positives = 258/482 (53%), Gaps = 11/482 (2%)
Query: 22 FVDGQWLETASET-FNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRS 80
FV G +E S+ F V +P + + +AT + + + + A +A + + K++ RS
Sbjct: 209 FVAGNHVEFPSDRKFEVIEPRSGKPMATWHYATRDQVDLTVKEAKKAQKQWAKSSWMERS 268
Query: 81 TWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQP 140
L+ +L+ + +D+A NGK ++EA+ +V F +Y+ A + G + P
Sbjct: 269 EILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYFYSGIASDLLGQHV-P 327
Query: 141 NNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALA 200
+ S A+T R PVGV I WN+P + K ALA G V+ KP +P++AL LA
Sbjct: 328 LDASRYAYTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTALILA 387
Query: 201 HLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSAS-TMK 259
+ + AG P GVFNV+ T + L V K+SFTGS GK +MK A +K
Sbjct: 388 EILKSAGLPDGVFNVIQGDAETAQ---DLIHHDGVSKVSFTGSIPTGKKIMKACADRNIK 444
Query: 260 KLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLA 319
++ ELGG + +IVFDDAD++ AV+ +++ F GQ C A+++ V ++++ F +KL
Sbjct: 445 PVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLV 504
Query: 320 KQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELG--PNF 377
+ IG L T G I+ KVE ++ A+ +GA + G R+ G F
Sbjct: 505 DHTQKMKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGLENGF 564
Query: 378 Y-APTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTV 436
Y +P +L+ + V ++E FG + +IPFDT +E + ANDT++GLA+ + +K++
Sbjct: 565 YLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTKDLSRS 624
Query: 437 YTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI--GNLP 494
Y V+E L G V NT +PFGGV ESGFGRE +E YT +K++ + G P
Sbjct: 625 YRVSEQLNAGNVYVNTYNDVSPLVPFGGVGESGFGRENGTAVLEHYTHLKSVFVNTGTCP 684
Query: 495 AP 496
P
Sbjct: 685 NP 686
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 251 bits (640), Expect = 2e-66
Identities = 161/479 (33%), Positives = 259/479 (53%), Gaps = 34/479 (7%)
Query: 22 FVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRL--FKKTTPKT 78
F+DG+++ ++ TF +PAT + I LP ++ + A+ +A +AF +++ + +
Sbjct: 431 FIDGKFVGSSDGRTFKTINPATEKPICELPLATVADVDRAVRAAKKAFERGEWRQMSARE 490
Query: 79 RSTWLRNLYNLMMENVDDLAKIITWENGKALSEA-QGEVKYAASYFEWYAEEAVRMYGTT 137
R L L LM E+ ++LA + + + G + A + V + + ++A ++ G T
Sbjct: 491 RGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTHVGMSIDVWRYFAGWCDKIQGKT 550
Query: 138 IQPNNG---SNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPL 194
I +N N T+R+P+GV G+I PWN+P M++ K A LAA +++
Sbjct: 551 IPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKMAACLAAAKIKLIEIS----- 605
Query: 195 SALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQS 254
GV N+V + G L P V+KI FTGST +G +M+
Sbjct: 606 ----------------GVINIVTGSGSL--VGNRLTAHPDVRKIGFTGSTEIGATVMESC 647
Query: 255 A-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDS 313
A S +KK+S ELGG +P+I+F DADLE+AV Q + F G+ C+ A R+++ ++I D
Sbjct: 648 AKSNIKKVSLELGGKSPLIIFADADLEKAVKQACGAVFFNKGENCIAAGRVFIAKSIHDD 707
Query: 314 FAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPEL 373
F +KL ++ ++ IG LD T HG + + K+ +V+ A+ GAK V G RL
Sbjct: 708 FVKKLVEEAKQYQIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAGGAKVEVGGKRLERE 767
Query: 374 GPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPF--DTMEEVVGYANDTELGLASYVFSK 431
G ++ PT+LS++ +E+FGP+ + F D +E+V+ ANDTE GLA+ VF++
Sbjct: 768 G-LYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRANDTEFGLAAGVFTR 826
Query: 432 NIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
+ VAEAL G V NT ++ PFGG K+SGFG++ + +Y V KTITI
Sbjct: 827 DSSKSLRVAEALHAGTVFVNTYQKTDVAAPFGGFKQSGFGKDMGEEALNEYLVTKTITI 885
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 246 bits (627), Expect = 7e-65
Identities = 162/496 (32%), Positives = 253/496 (50%), Gaps = 20/496 (4%)
Query: 9 PEFKNSDLIRKGAFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEA 67
P+ K S G F++ ++ ++ +T +PAT E I + + + + +A+ +A A
Sbjct: 11 PQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAA 70
Query: 68 F-RLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKAL-SEAQGEVKYAASYFEW 125
F ++ KT+ + R +L NL L+ E D LA + T + GK S A+G++ +
Sbjct: 71 FDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRY 130
Query: 126 YAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVV 185
+A A + P + A+T++ P GV I PWN+P AM K ALAAG TV+
Sbjct: 131 FAGSADKFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVI 190
Query: 186 VKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGL----ALCESPKVKKISFT 241
+KP T LS L A L +KAGFP GV N+V P +G AL + KISFT
Sbjct: 191 IKPAENTSLSLLYFATLIKKAGFPPGVVNIV------PGYGSLVGQALASHMDIDKISFT 244
Query: 242 GSTNVGKILMKQSA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVC 300
GST VG +++ S S +K ++ E GG +P +VF+DADL++A+ F GQ C
Sbjct: 245 GSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTA 304
Query: 301 ANRIYVQRTIIDSFAEKLAKQVNEFVIGHG----LDSKTTHGCLINENAIKKVEAHVKDA 356
+R+YVQ +I D F EK + + G D K G +I+ +++++++
Sbjct: 305 NSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERG 364
Query: 357 LEKGAKTVVAGGRLPELGPN--FYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVV 414
+ + P G F PT+ + VP T+ + +DE FGP+ + F ++ +
Sbjct: 365 KREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDAL 424
Query: 415 GYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREG 474
ANDT GLAS VF+K++ + A ++ G V N+ + T+PFGG K SG GRE
Sbjct: 425 KLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGREL 484
Query: 475 SLHGIEDYTVIKTITI 490
G++ Y K + I
Sbjct: 485 GQSGVDTYLQTKAVHI 500
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 245 bits (626), Expect = 1e-64
Identities = 151/472 (31%), Positives = 249/472 (51%), Gaps = 10/472 (2%)
Query: 25 GQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWLR 84
G + + + +P+T + +PD + + +A+++A EAF+ +KKTT + RS L
Sbjct: 33 GNEFARSEKLMDSVNPSTGKPWIKIPDGTAREVDQAVEAAKEAFKTWKKTTVQQRSALLN 92
Query: 85 NLYNLMMENVDDLAKIITWENGKALSEAQG-EVKYAASYFEWYAEEAVRMYGTT--IQPN 141
+ NL+ E DD+A + + + GK + A+ ++ F +A A+ T+ ++
Sbjct: 93 KVANLIEEFNDDIAILESRDQGKPIGLAKVMDIPRCVQNFRDFANAALYSLSTSTILEQP 152
Query: 142 NGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAH 201
G + PVGV G+I PWN P +++ K AL AG TVV KP T ++A L H
Sbjct: 153 TGKFVNYVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEMTSVTAWVLMH 212
Query: 202 LAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKL 261
+ GFP GV N+V+ ++ G L + V ISFTGST +GK + + A KK+
Sbjct: 213 AFKLVGFPPGVVNMVIGEGKSA--GQRLVDHVDVPLISFTGSTVIGKKIQEDGAKLNKKV 270
Query: 262 SFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQ 321
S E+GG P IV+ + + + S F G+ C+C +R++VQ+ I F + ++
Sbjct: 271 SLEMGGKNPGIVYSNYR-KSDIASIARSSFLNQGEICLCTSRLFVQKPIFADFVKSYVEE 329
Query: 322 VNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN---FY 378
+F +G ++ G + ++ +KV+++++ A ++GA + G + G F
Sbjct: 330 AKKFTVGDPT-TQVQIGAMNSKVHYEKVKSYIELAKKEGADILCGGVTTIQNGCENGYFI 388
Query: 379 APTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYT 438
PTV+ + + V DE FGP+ + PFDT EEV+ AN T GL++ V+S + D +
Sbjct: 389 TPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVIERANSTPYGLSATVWSSDSDELLN 448
Query: 439 VAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
A L G V CNT L + ++PFGG K+SG GREG + Y+ KT+ +
Sbjct: 449 TANELRAGTVWCNTWLARDLSMPFGGCKQSGNGREGLHDSLHFYSDAKTVCV 500
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 244 bits (623), Expect = 2e-64
Identities = 164/493 (33%), Positives = 255/493 (51%), Gaps = 14/493 (2%)
Query: 9 PEFKNSDLIRKGAFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEA 67
P+ K S G F++ ++ ++ +T +PAT E I + + + + +A+ +A A
Sbjct: 11 PQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAA 70
Query: 68 F-RLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKAL-SEAQGEVKYAASYFEW 125
F ++ KT+ + R +L NL L+ E D LA + T + GK S A+ ++ +
Sbjct: 71 FDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRY 130
Query: 126 YAEEAVRM-YGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTV 184
YA + G TI P + A+T++ P GV I PWN+P AM RK ALAAG TV
Sbjct: 131 YAGAVDKFNMGETI-PLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTV 189
Query: 185 VVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGST 244
++KP T LS L A L +KAGFP GV NV+ G AL + KISFTGST
Sbjct: 190 IIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSV--VGKALGTHMDIDKISFTGST 247
Query: 245 NVGKILMKQSA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANR 303
VG +++ S S +K ++ E GG +P +VF+DADL++A+ F GQ C +R
Sbjct: 248 KVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSR 307
Query: 304 IYVQRTIIDSFAEKLAKQVNEFVIGHG----LDSKTTHGCLINENAIKKVEAHVKDALEK 359
+YVQ +I D F EK + + G D K G +I+ +++++++ ++
Sbjct: 308 VYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKE 367
Query: 360 GAKTVVAGGRLPELGPN--FYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYA 417
+ P G F PT+ + VP T+ + +DE FGP+ + F ++ + A
Sbjct: 368 EKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLA 427
Query: 418 NDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLH 477
NDT GLAS VF+K++ + A ++ G V N E +PFGG K SG GRE
Sbjct: 428 NDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDT 487
Query: 478 GIEDYTVIKTITI 490
G+++Y IK++ +
Sbjct: 488 GVDNYLQIKSVHV 500
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 232 bits (591), Expect = 1e-60
Identities = 157/488 (32%), Positives = 247/488 (50%), Gaps = 50/488 (10%)
Query: 22 FVDGQWLETA-SETFNVTDPAT------LEVIATLPDQSIEVIHEAIDSAAEAFRLFK-- 72
F+DG+W E + + +PAT L+ I +P + E + A+++A A K
Sbjct: 11 FIDGEWREPILKKRIPIVNPATEEDLYVLDEIGDIPAATTEDVDVAVNAARRALSRNKGK 70
Query: 73 ---KTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEE 129
K R+ +LR + + E DLAK+ + GK L EA ++ A FE+YA+
Sbjct: 71 DWAKAPGAVRAKYLRAIAAKVNERKTDLAKLEALDCGKPLDEAVWDMDDVAGCFEFYADL 130
Query: 130 AVRMYGTTIQPNN---GSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVV 186
A + P + S +++ ++QP+GV G+I PWN+P M K +LAAGCT ++
Sbjct: 131 AEGLDAKQKAPVSLPMESFKSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGCTAIL 190
Query: 187 KPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNV 246
KP ++ L LA + + G P GV NV LT + E G L P V KI+FTGS
Sbjct: 191 KPSELASVTCLELADICREVGLPPGVLNV-LTGFGS-EAGAPLASHPGVDKIAFTGSFAT 248
Query: 247 GKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYV 306
G +M +A +K +S ELGG +P+IVFDD DL++A + F GQ C +R+ V
Sbjct: 249 GSKVMTAAAQLVKPVSMELGGKSPLIVFDDVDLDKAAEWALFGCFWTNGQICSATSRLLV 308
Query: 307 QRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAK--TV 364
+I F EKL K + D +E+G + V
Sbjct: 309 HESIASEFIEKLVKWSKNI--------------------------KISDPMEEGCRLGPV 342
Query: 365 VAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGL 424
V+ G+ E G F PT+++ V ++ + ++E FGP+ + F + +E + AND+ GL
Sbjct: 343 VSKGQHLEKG-FFIEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIELANDSHYGL 401
Query: 425 ASYVFSKNIDTVYTVAEALETGMV--SCNTGLFSECTIPFGGVKESGFGREGSLHGIEDY 482
+ V S + + ++EA E G+V +C+ F++ P+GGVK SGFGRE G+++Y
Sbjct: 402 GAAVISNDTERCDRISEAFEAGIVWINCSQPCFTQA--PWGGVKRSGFGRELGEWGLDNY 459
Query: 483 TVIKTITI 490
+K +T+
Sbjct: 460 LSVKQVTL 467
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 201 bits (511), Expect = 2e-51
Identities = 121/353 (34%), Positives = 199/353 (56%), Gaps = 13/353 (3%)
Query: 22 FVDGQWLET-ASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFR-LFKKTTPKTR 79
F++G++++ A T + +P EV+ + S + +A+ +A AF +++ TP+ R
Sbjct: 432 FINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQITPRQR 491
Query: 80 STWLRNLYNLMMENVDDLAKIITWENGKALSEA-QGEVKYAASYFEWYAEEAVRMYGTTI 138
+ NL +LM N ++LA I + ++G + A + V + + ++A ++ G TI
Sbjct: 492 GQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTI 551
Query: 139 -----QPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTP 193
+PNN FT ++P+GVCG+I PWN+P M++ K A +AAG T ++KP P
Sbjct: 552 PVNPARPNNVLT--FTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCP 609
Query: 194 LSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQ 253
L+AL A L +AGFP GV NV+ + + G A+ + V+K+ FTGST +GK +MK
Sbjct: 610 LTALKFAELTVRAGFPPGVINVL--PGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKS 667
Query: 254 SA-STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIID 312
A S +KK S ELGG +P+I+F D D+++AV + S F G+ C+ A R++V+ I D
Sbjct: 668 CADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHD 727
Query: 313 SFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVV 365
F ++ K + IG LD T HG ++ K+ + +++GAK VV
Sbjct: 728 EFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVV 780
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 200 bits (508), Expect = 5e-51
Identities = 149/474 (31%), Positives = 231/474 (48%), Gaps = 12/474 (2%)
Query: 25 GQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWLR 84
G+W + + PA IA + + +++ AI A +A+ + + R +R
Sbjct: 30 GKWA-ASGQVVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYNDWCEVPAPRRGEIVR 88
Query: 85 NLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQPNNGS 144
+ + + + +L K+++ E GK +E GEV+ + YA R I P+
Sbjct: 89 QIGDKLRTQLQNLGKLVSLEMGKISAEGVGEVQEYVDICD-YATGLSRSLEGKIFPSERP 147
Query: 145 NRAFTVR-QPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLA 203
A + P+GV G+I +NFP A+ AL G +VV KP TPL+A+A+ L
Sbjct: 148 GHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLV 207
Query: 204 EKAGFPKGVFNVVLTATRTPE--FGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKL 261
E+ V N L + E G AL + +V +SFTGS+ +GKI+ +Q + KL
Sbjct: 208 EEVLVANNV-NPALCSLVCGEGDVGQALVKDKRVNLVSFTGSSEIGKIVGQQVQARFGKL 266
Query: 262 SFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQ 321
ELGGN +IV +DADL V T+ + GQ C R+ V + D E+L K
Sbjct: 267 LLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLERLKKA 326
Query: 322 VNEFV--IGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYA 379
+F IG LDS T G L N+ A+ K +A V +A+ G K + GG++ E NF
Sbjct: 327 YAQFESRIGCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGK-IEYGGKVLERDGNFVL 385
Query: 380 PTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVY-- 437
PT+++ + + V ETF P+ ++ F T+EE + N+ + GL+S +F+ NI V+
Sbjct: 386 PTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQGLSSSLFTTNIQNVFKW 445
Query: 438 TVAEALETGMVSCNTGLF-SECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
+ + G+V+ N +E FGG KE+G GRE Y T TI
Sbjct: 446 MGPKGSDCGIVNVNIPTSGAEIGGAFGGEKETGGGRESGSDSWRQYMRRSTCTI 499
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 194 bits (494), Expect = 2e-49
Identities = 134/477 (28%), Positives = 226/477 (47%), Gaps = 15/477 (3%)
Query: 22 FVDGQWLETASETF-NVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRS 80
++DGQ +E+ + F +T+PAT EVIA +P+ + + A+DSA AF +K T+P TR
Sbjct: 33 WIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTSPLTRQ 92
Query: 81 TWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQP 140
+ L L+ ++ LA+ IT E GK L +A+G+V E M G T+
Sbjct: 93 QCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETLPN 152
Query: 141 NNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALA 200
+ + R P+GV ICP+NFP+ + ALA G T+V+KP Q P +A L
Sbjct: 153 VSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLV 212
Query: 201 HLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKK 260
LA++AG P G N++ F +C++P +K ISF G GK + ++ A K+
Sbjct: 213 ELAKEAGVPDGCVNIIHGQHSAVNF---ICDNPDIKAISFVGGDAAGKHIYERGAKNGKR 269
Query: 261 LSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAK 320
+ +G ++ DA+ EQ + Q + F GQ C+ + ++ +L +
Sbjct: 270 VQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGE-ARAWLPELVE 328
Query: 321 QVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELG---PNF 377
+ + G T G LI++ + +V ++ A ++GA+ + G + G NF
Sbjct: 329 KAKNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGNF 388
Query: 378 YAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVY 437
PT+L+ V ++E FGP+ ++ + + E + N+ G + +F+ N T
Sbjct: 389 VGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFTSNGATAR 448
Query: 438 TVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLH-----GIEDYTVIKTIT 489
++ G + N + +P S G L+ GI+ YT KT+T
Sbjct: 449 KFTNEVDVGQIGINVPI--PVPLPMFSFTGSRGSFLGDLNFYGKAGIQFYTQWKTVT 503
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 193 bits (490), Expect = 6e-49
Identities = 135/467 (28%), Positives = 229/467 (48%), Gaps = 26/467 (5%)
Query: 39 DPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLA 98
+PAT++ + P S + E + + +A + + +++ K R +LR L ++E+ + +
Sbjct: 70 EPATMKYLGYFPALSPTEVEERVTLSRKAQKTWAQSSFKLRRQFLRILLKYIIEHQELIC 129
Query: 99 KIITWENGKALSEAQ-GEVKYAASYFEWYAEEAVRMYGTTIQPNN-GSNRAFTVR----- 151
++ + + GK + +A GE+ W E R ++P + S RA +
Sbjct: 130 EVSSRDTGKTMVDASLGEIMTTCEKITWLLSEGERW----LKPESRSSGRAMLHKVSRVE 185
Query: 152 -QPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKA---- 206
P+GV G I PWN+P I AA+ +G +V+K S + + A
Sbjct: 186 FHPLGVIGAIVPWNYPFHNIFNPMLAAVFSGNGIVIKVSEHASWSGCFYFRIIQAALAAV 245
Query: 207 GFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELG 266
G P+ + +V+ T E G AL S V K+ F GST VGK++M+ +A T+ ++ ELG
Sbjct: 246 GAPENLVDVI---TGFAETGEALVSS--VDKMIFVGSTAVGKMIMRNAAETLTPVTLELG 300
Query: 267 GNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFV 326
G I+ +DAD+ + + GQ C A R YV + I +F ++ K V
Sbjct: 301 GKDAFIICEDADVSHVAQVAVRGTLQSSGQNCAGAERFYVHKDIYTAFIGQVTKIVKSVS 360
Query: 327 IGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAG--GRLPE-LGPNFYAPTVL 383
G L + G + + + +++ V DAL+KGA+ V G G L E ++ PTVL
Sbjct: 361 AGPPLTGRYDMGAICLQEHSEHLQSLVNDALDKGAEIAVRGSFGHLGEDAVDQYFPPTVL 420
Query: 384 SHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEAL 443
+V + K+E FGP+ ++ F T EEV+ AND+ L VFS + +A +
Sbjct: 421 INVNHNMKIMKEEAFGPIMPIMQFSTDEEVIKLANDSRYALGCAVFSGSKHRAKQIASQI 480
Query: 444 ETGMVSCN--TGLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTI 488
+ G+ + N + ++PFGGVK+SGFGR + G+ ++K++
Sbjct: 481 QCGVAAINDFASNYMCQSLPFGGVKDSGFGRFAGIEGLRACCLVKSV 527
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 190 bits (483), Expect = 4e-48
Identities = 145/505 (28%), Positives = 245/505 (47%), Gaps = 23/505 (4%)
Query: 1 MAGITGITPEFKNSDLIRKGAFVDGQWLETAS-ETFNVTDPATLEVIATLPDQSIEVIHE 59
MAG TG+ E + ++ + + DG+W ++S ++ + +PAT + + + E ++
Sbjct: 1 MAG-TGLFAEILDGEVYKY--YADGEWKTSSSGKSVAIMNPATRKTQYKVQACTQEEVNA 57
Query: 60 AIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYA 119
++ A A + + KT R+ L ++ +N +A+ + E K ++ EV +
Sbjct: 58 VMELAKSAQKSWAKTPLWKRAELLHKAAAILKDNKAPMAESLVKEIAKPAKDSVTEVVRS 117
Query: 120 ASYFEWYAEEAVRMYGT-------TIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITR 172
+ AEE VR+ G + N+ + T + P+GV I P+N+P +
Sbjct: 118 GDLISYCAEEGVRILGEGKFLLSDSFPGNDRTKYCLTSKIPLGVVLAIPPFNYPVNLAVS 177
Query: 173 KAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCES 232
K AL AG ++V+KP +Q +S L + H AGFPKG+ + + + E G L
Sbjct: 178 KIAPALIAGNSLVLKPPTQGAVSCLHMVHCFHLAGFPKGLISCI--TGKGSEIGDFLTMH 235
Query: 233 PKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFR 292
P V ISFTG + G + K++ M L ELGG IV DDADL+ + I F
Sbjct: 236 PAVNCISFTGG-DTGISISKKAG--MIPLQMELGGKDACIVLDDADLDLVASNIIKGGFS 292
Query: 293 GLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAH 352
GQ C + V ++ D EK+ +V + +G + + +++E++ +E
Sbjct: 293 YSGQRCTAVKVVLVMESVADELVEKVKAKVAKLTVGPP-EENSDITAVVSESSANFIEGL 351
Query: 353 VKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEE 412
V DA EKGA R N P +L +V + +E FGP+ ++ +++EE
Sbjct: 352 VMDAKEKGATFCQEYKR----EGNLIWPLLLDNVRPDMRIAWEEPFGPVVPVLRINSVEE 407
Query: 413 VVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTG-LFSECTIPFGGVKESGFG 471
+ + N + GL VF+K+I+ +++A+ETG V N+ PF G+K+SG G
Sbjct: 408 GINHCNASNFGLQGCVFTKDINKAILISDAMETGTVQINSAPARGPDHFPFQGLKDSGIG 467
Query: 472 REGSLHGIEDYTVIKTITIGNLPAP 496
+G + I T +KT T+ NLP P
Sbjct: 468 SQGVTNSINLMTKVKT-TVINLPTP 491
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 189 bits (479), Expect = 1e-47
Identities = 129/478 (26%), Positives = 229/478 (46%), Gaps = 13/478 (2%)
Query: 20 GAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTR 79
G++V G+W + + +PA + IA + + S+E + + + EA +++ + T R
Sbjct: 22 GSYVAGKW-QANGPLVSTLNPANNQPIAQVVEASLEDYEQGLKACEEAAKIWMQVTAPKR 80
Query: 80 STWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQ 139
+R + + + +D L ++++ E GK L+E GEV+ ++ + ++ G+ I
Sbjct: 81 GDIVRQIGDALRSKLDYLGRLLSLEMGKILAEGIGEVQEVIDMCDFAVGLSRQLNGSVIP 140
Query: 140 PNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALAL 199
++ + P+G+ G+I +NFP A++ A AL G VV K TPL +A+
Sbjct: 141 SERPNHMMLEMWNPLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAM 200
Query: 200 ----AHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSA 255
A + EK P +F + E G A+ + ++ +SFTGS+ VG ++ +
Sbjct: 201 TKLVAEVLEKNNLPGAIFTAMCGGA---EIGEAIAKDTRIPLVSFTGSSRVGSMVQQTVN 257
Query: 256 STMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFA 315
+ K EL GN +IV DDAD++ A + + GQ C R+ + ++ D
Sbjct: 258 ARSGKTLLELSGNNAIIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVL 317
Query: 316 EKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGP 375
E+L + IG+ L+ T G L + K E ++ +G K ++ GG+ E
Sbjct: 318 EQLLTSYKQVKIGNPLEKGTLLGPLHTPESKKNFEKGIEVIKSQGGK-ILTGGKAVEGEG 376
Query: 376 NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDT 435
NF PT++ + + A V K+E F P+ ++ F + E V N GL+S +F++N +
Sbjct: 377 NFVEPTII-EISADAAVVKEELFAPVLYVLKFKSFGEAVAINNSVPQGLSSSIFTRNPEN 435
Query: 436 VYTVAEAL--ETGMVSCNTGL-FSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
++ L + G+V+ N +E FGG K +G GRE + Y T TI
Sbjct: 436 IFRWIGPLGSDCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRRSTCTI 493
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 186 bits (471), Expect = 9e-47
Identities = 123/476 (25%), Positives = 230/476 (47%), Gaps = 15/476 (3%)
Query: 23 VDGQWLETASETF-NVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRST 81
+ G ++E+ S +F +V +PAT EV++ +P + E A+ +A +AF L++ T TR
Sbjct: 118 IGGSFVESQSSSFIDVINPATQEVVSKVPLTTNEEFKAAVSAAKQAFPLWRNTPITTRQR 177
Query: 82 WLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQPN 141
+ L+ +N+D LA IT E GK L ++ G++ E A G +
Sbjct: 178 VMLKFQELIRKNMDKLAMNITTEQGKTLKDSHGDIFRGLEVVEHACGMATLQMGEYLPNV 237
Query: 142 NGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAH 201
+ +++R+P+GVC ICP+NFP+ + A+ G T ++KP + P +++ LA
Sbjct: 238 SNGVDTYSIREPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFILKPSEKDPGASVILAE 297
Query: 202 LAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKL 261
LA +AG P GV N+V T A+C+ ++ +SF GS G + ++A+ K++
Sbjct: 298 LAMEAGLPDGVLNIVHGTNDTVN---AICDDEDIRAVSFVGSNTAGMHIYARAAAKGKRI 354
Query: 262 SFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQ 321
+G +V DA+++ + + + F GQ C+ + + V S+ +KL ++
Sbjct: 355 QSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCMALSTV-VFVGDAKSWEDKLVER 413
Query: 322 VNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELG---PNFY 378
+ G + G +I++ A +++ ++ ++ GAK ++ G + G NF
Sbjct: 414 AKALKVTCGSEPDADLGPVISKQAKERICRLIQSGVDDGAKLLLDGRDIVVPGYEKGNFI 473
Query: 379 APTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYT 438
PT+LS V K+E FGP+ + ++ +E + N + G + +F+ +
Sbjct: 474 GPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISIINKNKYGNGAAIFTSSGAAARK 533
Query: 439 VAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLH-----GIEDYTVIKTIT 489
+E G + N + +PF + G L+ G++ +T IKT+T
Sbjct: 534 FQMDIEAGQIGINVPI--PVPLPFFSFTGNKASFAGDLNFYGKAGVDFFTQIKTVT 587
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 183 bits (464), Expect = 6e-46
Identities = 126/475 (26%), Positives = 222/475 (46%), Gaps = 11/475 (2%)
Query: 22 FVDGQWLETASETF-NVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRS 80
F+ G+++E+ S+ + ++ +PAT EVI +P + + AI S AF + T+ +R
Sbjct: 43 FIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQ 102
Query: 81 TWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQP 140
L L+ EN+ ++AK+IT E GK L++A+G+V E M G T+
Sbjct: 103 QVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPS 162
Query: 141 NNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALA 200
++ R P+GVC I P+NFP+ + A+ G T ++KP + P + + LA
Sbjct: 163 ITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLA 222
Query: 201 HLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKK 260
L + +G P G N++ F +C+ P +K ISF GS G+ + ++ + K+
Sbjct: 223 KLLQDSGAPDGTLNIIHGQHEAVNF---ICDHPDIKAISFVGSNKAGEYIFERGSRHGKR 279
Query: 261 LSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAK 320
+ +G +V DA+ E + Q + + F GQ C+ + + + +L +
Sbjct: 280 VQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGE-AKKWLPELVE 338
Query: 321 QVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELG---PNF 377
+ G G LI A ++V + ++GA ++ G ++ G NF
Sbjct: 339 HAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNF 398
Query: 378 YAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVY 437
PT++S+V K+E FGP+ ++ +T++E + N+ G + +F+ N T
Sbjct: 399 VGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATAR 458
Query: 438 TVAEALETGMVSCNTGLFSECTI-PFGGVKESGFGREG--SLHGIEDYTVIKTIT 489
A ++ G V N + + F G + S G GI+ YT +KTIT
Sbjct: 459 KYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTIT 513
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 179 bits (455), Expect = 6e-45
Identities = 132/472 (27%), Positives = 218/472 (45%), Gaps = 8/472 (1%)
Query: 24 DGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWL 83
+G W E PA E IA + S+ E + A EA++++ R +
Sbjct: 28 NGSW-GGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIV 86
Query: 84 RNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQPNNG 143
R + + + E + L +++ E GK L E GEV+ + YA RM G I P+
Sbjct: 87 RQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICD-YAVGLSRMIGGPILPSER 145
Query: 144 SNRAFTVR-QPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHL 202
S A + PVG+ GII +NFP A+ A+ G + K T L ++A+ +
Sbjct: 146 SGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKI 205
Query: 203 AEKAGFPKGVFNVVLTAT-RTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKL 261
K + + + T + G A+ + +V +SFTGST VGK + +
Sbjct: 206 IAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRS 265
Query: 262 SFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQ 321
ELGGN +I F+DADL V + + GQ C A R+++ +I D +L K
Sbjct: 266 LLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKA 325
Query: 322 VNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPT 381
+ +G+ D +G L + A+ V++A ++G TVV GG++ + N+ PT
Sbjct: 326 YAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGG-TVVYGGKVMDRPGNYVEPT 384
Query: 382 VLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVY--TV 439
+++ + A + ETF P+ + F EEV + N+ + GL+S +F+K++ ++
Sbjct: 385 IVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLG 444
Query: 440 AEALETGMVSCNTGLF-SECTIPFGGVKESGFGREGSLHGIEDYTVIKTITI 490
+ + G+V+ N +E FGG K +G GRE + Y T TI
Sbjct: 445 PKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTI 496
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 179 bits (454), Expect = 8e-45
Identities = 128/474 (27%), Positives = 227/474 (47%), Gaps = 9/474 (1%)
Query: 25 GQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWLR 84
GQW + + DP T + IA + +++ + I A EA++ +++ R +R
Sbjct: 109 GQW-QGRGPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVR 167
Query: 85 NLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMY-GTTIQPNNG 143
+ + + + + L K+++ E GK SE QGEV+ + YA R+Y G I
Sbjct: 168 QIGDELRKYKEPLGKLVSLEVGKIYSEGQGEVQEFIDICD-YAVGLSRIYSGQLINSERA 226
Query: 144 SNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLA 203
+ +P+GV G+I +NFP+A+ A AL G +V+ K TPL ++A +
Sbjct: 227 DHSILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIV 286
Query: 204 EKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSF 263
+ + VV + G L +V +SFTGS G+ + + K+
Sbjct: 287 AEVLRRNNLPPVVTLCQGGTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVIL 346
Query: 264 ELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVN 323
ELGGN +I+ + A+++ A+ + GQ C RI V + D F ++L +
Sbjct: 347 ELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYK 406
Query: 324 EFV--IGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPT 381
+ + IGH L+++T G + + ++ +A + +A G TV GG + + + PT
Sbjct: 407 QLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGG-TVAFGGNVIQRDGFYVEPT 465
Query: 382 VLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVY--TV 439
V++ +P A V ETF P+ ++ +++ + + N+ E GL+S +F++NI +
Sbjct: 466 VITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIG 525
Query: 440 AEALETGMVSCNTGL-FSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITIGN 492
A+ + G+V+ NT +E FGG K +G GRE + Y TIT+ +
Sbjct: 526 AKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITVNH 579
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 178 bits (452), Expect = 1e-44
Identities = 124/476 (26%), Positives = 228/476 (47%), Gaps = 13/476 (2%)
Query: 22 FVDGQWLET-ASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRS 80
F+DG+++E+ +E +V DPAT +V+ +P + + A++S +AFR + + TR
Sbjct: 61 FIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQ 120
Query: 81 TWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFEWYAEEAVRMYGTTIQP 140
+ L L+ EN+ +LAK IT E GK L++A+G+V E G T+
Sbjct: 121 QVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGETVAN 180
Query: 141 NNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALA 200
+++ P+GV + P+NFP+ + A+ G T+++KP + P + + L
Sbjct: 181 VARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLM 240
Query: 201 HLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKK 260
L +AG P GV NV+ F +C++P++K +SF GS GK + +++ K+
Sbjct: 241 ELLNEAGCPPGVVNVIHGQHDAVNF---ICDAPEIKAVSFVGSDQAGKYIYERAGKNGKR 297
Query: 261 LSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVC-ANRIYVQRTIIDSFAEKLA 319
+ +G I+ DA+ E + Q + F GQ C+ + ++V ++ L
Sbjct: 298 VQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDA--QAWIPDLV 355
Query: 320 KQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN--- 376
++ + + G T G +I+ + +++ ++ +++GAK ++ G ++ G
Sbjct: 356 ERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDGY 415
Query: 377 FYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTV 436
F PT+LS V + +E FGP+ ++ DT+++ +G N G + VF+ N
Sbjct: 416 FVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAAA 475
Query: 437 YTVAEALETGMVSCNTGLFSECTI-PFGGVKESGFGREG--SLHGIEDYTVIKTIT 489
++ G V N + + F G + S G GI+ YT KT+T
Sbjct: 476 RKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTVT 531
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 166 bits (420), Expect = 7e-41
Identities = 122/448 (27%), Positives = 199/448 (44%), Gaps = 9/448 (2%)
Query: 57 IHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQ-GE 115
I ++I A EA + +K T+ R +L+ L ++ N D A+I + GK L +A GE
Sbjct: 27 IDQSIILAEEAQKEWKSTSFAERRNFLKALKENIIRNQDKYAEIACKDTGKTLVDAAFGE 86
Query: 116 VKYAASYFEWYAEEAVRMYGTTIQPNN---GSNRAFTVRQPVGVCGIICPWNFPSAMITR 172
+ W + T +PN+ + +P+GV + WN+P
Sbjct: 87 ILVTLEKINWTLANGEQSLRPTKRPNSLLTSYKGGYVKYEPLGVIAALVSWNYPLHNALG 146
Query: 173 KAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVF-NVVLTATRTPEFGLALCE 231
+AL AG +VVK T S + G +V T P+ L
Sbjct: 147 PIISALFAGNAIVVKGSELTAWSTHQYCEMVRSLLQSMGHSPELVQCITCLPDVADHLTS 206
Query: 232 SPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKF 291
+K I+F GS + K++ +A + L ELGG P I+ DD LE+ ++ + F
Sbjct: 207 HSGIKHITFIGSQPIAKLVAASAAKQLTPLCLELGGKDPCILTDDHRLEEILSIVMRGVF 266
Query: 292 RGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEA 351
+ GQ C+ RI + D+ KL +++ +G + G +++ N +E+
Sbjct: 267 QSAGQNCIGIERIIALDGVYDTIITKLYNRISTMRLGMYTQNDVDMGAMVSNNRFDHLES 326
Query: 352 HVKDALEKGAKTVVAGGRL--PELGP-NFYAPTVLSHVPSTAVVNKDETFGPLCALIPFD 408
++DA+ KGA+ V G R P+ N++ PT+L + + ++E F P+ +
Sbjct: 327 LIQDAVSKGARLVYGGHRFQHPKYPKGNYFLPTLLVDATNEMKIAQEECFAPIALVFRAK 386
Query: 409 TMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNT-GLFSECTIPFGGVKE 467
+ E + AN TE GL + VF ++ + LETGMV+ N G F +PFGG K+
Sbjct: 387 SPEHALEIANGTEFGLGASVFGRDKQLCQYFTDNLETGMVAVNDFGAFYLLQMPFGGCKK 446
Query: 468 SGFGREGSLHGIEDYTVIKTITIGNLPA 495
SG+GR G+ K I A
Sbjct: 447 SGYGRFAGYEGLRGICNSKAIAYDRFSA 474
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 156 bits (394), Expect = 8e-38
Identities = 126/477 (26%), Positives = 211/477 (43%), Gaps = 22/477 (4%)
Query: 40 PATLEVIATLPDQSIEVIHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAK 99
PAT + + + P ++ I E + A +A + + R L +L++ ++ N D +A+
Sbjct: 117 PATGQYLGSFPSKTEADIDEMVSKAGKAQSTWGNSDFSRRLRVLASLHDYILNNQDLIAR 176
Query: 100 IITWENGKALSEAQ-GEVKYAASYFEWYAEEAVRMYGTTIQPNNGS-----NRAFTVR-Q 152
+ ++GK + +A GE+ +W + R + +P + + +R +
Sbjct: 177 VACRDSGKTMLDASMGEILVTLEKIQWTIKHGQRALQPSRRPGPTNFFMKWYKGAEIRYE 236
Query: 153 PVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKA-----G 207
P+GV I WN+P + AAL G +VVK Q S+ L K
Sbjct: 237 PLGVISSIVSWNYPFHNLLGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKCLEACDE 296
Query: 208 FPKGV-FNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELG 266
P V L T + P K I+F GS V ++K +A ++ + ELG
Sbjct: 297 DPDLVQLCYCLPPTENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKSLTPVVVELG 356
Query: 267 GNAPVIVFDDADLEQAVTQTIL-SKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEF 325
G IV D A A++ I+ F+ GQ C+ R+ V + D + L ++
Sbjct: 357 GKDAFIVLDSAKNLDALSSIIMRGTFQSSGQNCIGIERVIVSKENYDDLVKILNDRMTAN 416
Query: 326 VIGHGLD----SKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRL--PELGP-NFY 378
+ G D G +I++N ++EA VKDA+ KGA+ + G R P+ +++
Sbjct: 417 PLRQGSDIDHLENVDMGAMISDNRFDELEALVKDAVAKGARLLQGGSRFKHPKYPQGHYF 476
Query: 379 APTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYT 438
PT+L V + ++E FGP+ ++ + V AN GL VF +I
Sbjct: 477 QPTLLVDVTPEMKIAQNEVFGPILVMMKAKNTDHCVQLANSAPFGLGGSVFGADIKECNY 536
Query: 439 VAEALETGMVSCNT-GLFSECTIPFGGVKESGFGREGSLHGIEDYTVIKTITIGNLP 494
VA +L+TG V+ N F C +PFGG+ SG+G+ G G+ K++ LP
Sbjct: 537 VANSLQTGNVAINDFATFYVCQLPFGGINGSGYGKFGGEEGLLGLCNAKSVCFDTLP 593
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 149 bits (376), Expect = 9e-36
Identities = 123/441 (27%), Positives = 203/441 (45%), Gaps = 21/441 (4%)
Query: 57 IHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEV 116
+H +++ F + R L L L+ EN L +++ W++ + E +
Sbjct: 3 LHRIVEAQRAYFNTGATKPAEFRKEQLLQLKKLIEENRAALTEVV-WKDLRRRHEVTEPM 61
Query: 117 KYAASYFE--WYAEEAVR-MYGTTIQPNNGS---NRAFTVRQPVGVCGIICPWNFPSAMI 170
+ S E +Y + M T ++P + ++ + V+ P GV +I PWN+P +M+
Sbjct: 62 ELGGSLEEIAYYLKNLDDWMKPTYVEPTVATLPTDKPYIVKDPKGVVLVISPWNYPVSMV 121
Query: 171 TRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALC 230
++AAG T+V+KP + +A+ L K PK V + PE L
Sbjct: 122 LLPMIPSIAAGNTIVIKPSELSENTAILFEKLIPKYFDPK---YVTIVNGGIPETTELLK 178
Query: 231 ESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSK 290
E + I +TG V KI+M +A + ++ ELGG PV+V DDAD+E + + K
Sbjct: 179 E--RFDHIIYTGCPPVAKIIMAAAAKHLTPVTLELGGKCPVVVEDDADIEISAQRIARGK 236
Query: 291 FRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVE 350
+ GQTC+ + I V F + K + EF G+ +SK + +IN+ ++
Sbjct: 237 WLNCGQTCLAPDYILVSSATKPKFVAAIQKCLKEFYGGNAKESK-DYSRVINQRHFDRIS 295
Query: 351 AHVKDALEKGAKTVVAGG-RLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDT 409
A L++ V+AG + F PTVL V T DE FGP+ +I
Sbjct: 296 A----LLDESKGVVLAGNEESRDRSDRFIPPTVLD-VEKTDPFMHDEIFGPVLPIITVKN 350
Query: 410 MEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLF--SECTIPFGGVKE 467
+ E + + N E LA+Y+F+K+ V +G V+ N + + T+PFGGV
Sbjct: 351 LCESIDFINKGEKPLAAYIFTKDEAKVQRFLNETTSGGVTVNDVIMHVAVITLPFGGVGV 410
Query: 468 SGFGREGSLHGIEDYTVIKTI 488
SG GR G + +T K++
Sbjct: 411 SGMGRYRGKFGFDTFTHEKSV 431
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 146 bits (368), Expect = 8e-35
Identities = 121/437 (27%), Positives = 194/437 (43%), Gaps = 20/437 (4%)
Query: 59 EAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQ----- 113
E +++ + FR + K R L L + EN + L++ + W++ + E+
Sbjct: 5 ELVETQRKYFRTGETKPVKFRKQQLLKLKKFIEENREALSEAV-WKDLRRRHESTEILEI 63
Query: 114 GEVKYAASYFEWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRK 173
G YF ++ V+ ++ + P GV II PWN+P +MI
Sbjct: 64 GMTIQEIDYFLKNIDDWVKPTHVEKTFTTALDKPVIEKDPKGVVLIISPWNYPVSMILLP 123
Query: 174 AGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESP 233
A+AAG TVV+KP + A L K K V + PE L E
Sbjct: 124 MVPAIAAGNTVVIKPSELSENVAATFEKLIPKYFESK---YVTVVNGGIPETTDLLKE-- 178
Query: 234 KVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRG 293
+ I +TG V KI+M +A + ++ ELGG PV+V DDAD++ + + K+
Sbjct: 179 RFDHILYTGCPPVAKIIMTAAAKHLTPVTLELGGKCPVVVEDDADIDISAKRIAWGKWLN 238
Query: 294 LGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHV 353
GQTC+ + I V T+ + K VNEF G + + + +IN+ ++
Sbjct: 239 CGQTCLAPDYILVNSTVKPKLVAAIRKYVNEF-YGEDVKASKDYARMINQRHFDRISG-- 295
Query: 354 KDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEV 413
L+K V+ GG + Y P + V + DE FGP+ +I + E
Sbjct: 296 --LLDKTQGAVLIGGERDR--ADLYIPPTVLDVEKSDPFMHDEIFGPVLPIITVQSFSES 351
Query: 414 VGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGL--FSECTIPFGGVKESGFG 471
+ Y D E LA+Y+F++N V + +G V+ N L + T+PFGGV SG G
Sbjct: 352 LEYIADGEKPLAAYIFTRNEAKVKRLLNETSSGGVTVNDVLMHITVDTLPFGGVGVSGMG 411
Query: 472 REGSLHGIEDYTVIKTI 488
R +G + +T K++
Sbjct: 412 RYRGKYGFDTFTHEKSV 428
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 144 bits (364), Expect = 2e-34
Identities = 127/439 (28%), Positives = 202/439 (45%), Gaps = 36/439 (8%)
Query: 57 IHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQ--- 113
I EA+ A AF + + R L L L+ E +L + + K A
Sbjct: 4 ISEAVKRARAAFSSGRTRPLQFRFQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEE 63
Query: 114 -----GEVKYAASYF-EWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPS 167
E++Y EW A+E V P + + +P+GV +I WN+P
Sbjct: 64 VVYVLEEIEYMIQKLPEWAADEPVEK-----TPQTQQDELYIHSEPLGVVLVIGTWNYPF 118
Query: 168 AMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGL 227
+ + A+AAG VV+KP + A LA + + K ++ V+ PE
Sbjct: 119 NLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGV--PETTE 175
Query: 228 ALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTI 287
L E + I +TGST VGKI+M +A + ++ ELGG +P V + DL+ A +
Sbjct: 176 LLKE--RFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIA 233
Query: 288 LSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTT--HGCLINENA 345
KF GQTCV + I +I + EKL K + EF +G D+K + +G +I+
Sbjct: 234 WGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF---YGEDAKKSRDYGRIISARH 290
Query: 346 IKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALI 405
++V L +G K VA G + + APT+L+ V + V ++E FGP+ ++
Sbjct: 291 FQRVM-----GLIEGQK--VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV 343
Query: 406 PFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGL--FSECTIPFG 463
++EE + + N E LA Y+FS N + + +G V+ N + + ++PFG
Sbjct: 344 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG 403
Query: 464 GVKESGFGREGSLHGIEDY 482
GV SG GS HG + +
Sbjct: 404 GVGNSGM---GSYHGKKSF 419
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 144 bits (364), Expect = 2e-34
Identities = 127/439 (28%), Positives = 202/439 (45%), Gaps = 36/439 (8%)
Query: 57 IHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQ--- 113
I EA+ A AF + + R L L L+ E +L + + K A
Sbjct: 4 ISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEE 63
Query: 114 -----GEVKYAASYF-EWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPS 167
E++Y EW A+E V P + + +P+GV +I WN+P
Sbjct: 64 VVYVLEEIEYMIQKLPEWAADEPVEK-----TPQTQQDELYIHSEPLGVVLVIGTWNYPF 118
Query: 168 AMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGL 227
+ + A+AAG VV+KP + A LA + + K ++ V+ PE
Sbjct: 119 NLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGV--PETTE 175
Query: 228 ALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTI 287
L E + I +TGST VGKI+M +A + ++ ELGG +P V + DL+ A +
Sbjct: 176 LLKE--RFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIA 233
Query: 288 LSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTT--HGCLINENA 345
KF GQTCV + I +I + EKL K + EF +G D+K + +G +I+
Sbjct: 234 WGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF---YGEDAKKSRDYGRIISARH 290
Query: 346 IKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALI 405
++V L +G K VA G + + APT+L+ V + V ++E FGP+ ++
Sbjct: 291 FQRVM-----GLIEGQK--VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV 343
Query: 406 PFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGL--FSECTIPFG 463
++EE + + N E LA Y+FS N + + +G V+ N + + ++PFG
Sbjct: 344 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG 403
Query: 464 GVKESGFGREGSLHGIEDY 482
GV SG GS HG + +
Sbjct: 404 GVGNSGM---GSYHGKKSF 419
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 138 bits (347), Expect = 2e-32
Identities = 100/362 (27%), Positives = 172/362 (46%), Gaps = 20/362 (5%)
Query: 124 EWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCT 183
EW + V+ T+ + A+ QP+GV II WN+P + + A+AAG
Sbjct: 77 EWVTAKPVKKNVLTML-----DEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNA 131
Query: 184 VVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGS 243
V++KP + +A LA L + + ++ V+ L + I +TG+
Sbjct: 132 VIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELL----KQRFDHIFYTGN 186
Query: 244 TNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANR 303
T VGKI+M+ +A + ++ ELGG +P + D DL+ + K+ GQTC+ +
Sbjct: 187 TAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDY 246
Query: 304 IYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKT 363
I + ++ + K+ + V EF G + + +IN K++ +L +G K
Sbjct: 247 ILCEASLQNQIVWKIKETVKEF-YGENIKESPDYERIINLRHFKRIL-----SLLEGQK- 299
Query: 364 VVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELG 423
+ GG E + APTVL+ V V ++E FGP+ ++P ++E + + N+ E
Sbjct: 300 IAFGGETDE-ATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKP 358
Query: 424 LASYVFSKNIDTVYTVAEALETGMVSCNTGL--FSECTIPFGGVKESGFGREGSLHGIED 481
LA YVFS N + + + +G V+ N + F+ + PFGGV SG G H +
Sbjct: 359 LALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDT 418
Query: 482 YT 483
++
Sbjct: 419 FS 420
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 138 bits (347), Expect = 2e-32
Identities = 100/362 (27%), Positives = 172/362 (46%), Gaps = 20/362 (5%)
Query: 124 EWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCT 183
EW + V+ T+ + A+ QP+GV II WN+P + + A+AAG
Sbjct: 77 EWVTAKPVKKNVLTML-----DEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNA 131
Query: 184 VVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGS 243
V++KP + +A LA L + + ++ V+ L + I +TG+
Sbjct: 132 VIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELL----KQRFDHIFYTGN 186
Query: 244 TNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANR 303
T VGKI+M+ +A + ++ ELGG +P + D DL+ + K+ GQTC+ +
Sbjct: 187 TAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDY 246
Query: 304 IYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKT 363
I + ++ + K+ + V EF G + + +IN K++ +L +G K
Sbjct: 247 ILCEASLQNQIVWKIKETVKEF-YGENIKESPDYERIINLRHFKRIL-----SLLEGQK- 299
Query: 364 VVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELG 423
+ GG E + APTVL+ V V ++E FGP+ ++P ++E + + N+ E
Sbjct: 300 IAFGGETDE-ATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKP 358
Query: 424 LASYVFSKNIDTVYTVAEALETGMVSCNTGL--FSECTIPFGGVKESGFGREGSLHGIED 481
LA YVFS N + + + +G V+ N + F+ + PFGGV SG G H +
Sbjct: 359 LALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDT 418
Query: 482 YT 483
++
Sbjct: 419 FS 420
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 131 bits (330), Expect = 2e-30
Identities = 119/421 (28%), Positives = 180/421 (42%), Gaps = 35/421 (8%)
Query: 66 EAFRLFKKTTPKTRSTWLRNLYNLMMEN--------VDDLAKIITWENGKALSEAQGEVK 117
EAF + + R+ L+ L + EN DL K ++ +QGEV
Sbjct: 13 EAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVT 72
Query: 118 YAASYFE-WYAEEAVRMYGTTIQPNNGSNR---AFTVRQPVGVCGIICPWNFPSAMITRK 173
A W +E V P N + + AF ++P G+ II PWN+P +
Sbjct: 73 LALRNLRAWMKDERV--------PKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVP 124
Query: 174 AGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESP 233
ALAAG VV+KP + LA + + + F VVL + E G L
Sbjct: 125 LVGALAAGNCVVLKPSEISKNVEKILAEVLPQY-VDQSCFAVVLGGPQ--ETGQLL--EH 179
Query: 234 KVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFRG 293
+ I FTGS VGKI+M +A + ++ ELGG P V D+ D + + ++
Sbjct: 180 RFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFN 239
Query: 294 LGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHV 353
GQTCV + + + + L + F G S G +IN+ +++ A +
Sbjct: 240 AGQTCVAPDYVLCSPEMQERLLPALQSTITRF-YGDDPQSSPNLGRIINQKQFQRLRALL 298
Query: 354 KDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEV 413
G V GG+ E + APTVL V V ++E FGP+ ++ +++E
Sbjct: 299 ------GCGRVAIGGQSDE-SDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEA 351
Query: 414 VGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGL--FSECTIPFGGVKESGFG 471
+ + N E LA Y FS + V V +G N G + ++PFGGV SG G
Sbjct: 352 IEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMG 411
Query: 472 R 472
R
Sbjct: 412 R 412
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 131 bits (330), Expect = 2e-30
Identities = 111/382 (29%), Positives = 176/382 (46%), Gaps = 20/382 (5%)
Query: 95 DDLAKIITWENGKALSEAQGEVKYAASYFE-WYAEEAVRMYGTTIQPNNGSNRAFTVRQP 153
DDL K + +S + +K A + W A E + TT + A V +P
Sbjct: 58 DDLGKPELESSVYEVSLLRNSIKLALKQLKNWMAPEKAKTSLTTFPAS-----AEIVSEP 112
Query: 154 VGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVF 213
+GV +I WN+P + A++AG VV+KP P S+ L L E+ P V
Sbjct: 113 LGVVLVISAWNYPFLLSIDPVIGAISAGNAVVLKPSELAPASSALLTKLLEQYLDPSAVR 172
Query: 214 NVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIV 273
V T T AL E K KI +TGS+ +G+++M +A + + ELGG +PV+V
Sbjct: 173 VVEGAVTETS----ALLEQ-KWDKIFYTGSSKIGRVIMAAAAKHLTPVVLELGGKSPVVV 227
Query: 274 FDDADLEQAVTQTILSKFR-GLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLD 332
D DL+ V + I+ K+ GQ CV + I + + + ++ +F + ++
Sbjct: 228 DSDTDLKVTVRRIIVGKWGCNNGQACVSPDYILTTKEYAPKLIDAMKLELEKFYGKNPIE 287
Query: 333 SKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNF-YAPTVLSHVPSTAV 391
SK ++N N ++ + + D E K V G + E N APT+L VP ++
Sbjct: 288 SKDM-SRIVNSNHFDRL-SKLLDEKEVSDKIVYGGEKDRE---NLKIAPTILLDVPLDSL 342
Query: 392 VNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCN 451
+ +E FGPL ++ + +EE LA+Y+F+ N A + G + N
Sbjct: 343 IMSEEIFGPLLPILTLNNLEESFDVIRSRPKPLAAYLFTHNKKLKERFAATVSAGGIVVN 402
Query: 452 --TGLFSECTIPFGGVKESGFG 471
+ T+PFGGV ESG G
Sbjct: 403 DIAVHLALHTLPFGGVGESGMG 424
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 126 bits (316), Expect = 9e-29
Identities = 94/338 (27%), Positives = 162/338 (47%), Gaps = 15/338 (4%)
Query: 159 IICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLT 218
II P+NFP + AALAAG T+V+KP TP +A+ + +L AGFP G+ VV
Sbjct: 134 IIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQG 193
Query: 219 ATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIV---FD 275
A + L + K I +TGS VG I+ +++A ++ ELGG +P + F
Sbjct: 194 AI---DETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFK 250
Query: 276 DADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKT 335
++++ A+ + F GQ CV + + V ++I ++ +NEF D +T
Sbjct: 251 ASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFY--PSFDEQT 308
Query: 336 THGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN--FYAPTVLSHVPSTAVVN 393
+I+E A KK A + G+K V + + + PT++ ++ +
Sbjct: 309 DFTRMIHEPAYKKAVASINST--NGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDPLM 366
Query: 394 KDETFGPLCALIPFDTMEEVVG-YANDTELGLASYVFSKNIDTVYTVAEALETG-MVSCN 451
K E F P+ +I ++ ++E + + + L Y+FS + + + L +G V +
Sbjct: 367 KQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGD 426
Query: 452 TGLFSECT-IPFGGVKESGFGREGSLHGIEDYTVIKTI 488
T + T PFGG+ SG+G G +G ++ +TI
Sbjct: 427 TVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTI 464
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 125 bits (313), Expect = 2e-28
Identities = 97/327 (29%), Positives = 147/327 (44%), Gaps = 15/327 (4%)
Query: 148 FTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAG 207
F ++P G+ II PWN+P + L AG VV+KP + + LA + +
Sbjct: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQY- 76
Query: 208 FPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGG 267
+ F VVL + E G L K+ I FTGS VGKI+M + + ++ ELGG
Sbjct: 77 LDQSCFAVVLGGPQ--ETGQLL--EHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGG 132
Query: 268 NAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVI 327
P V D+ D + + + GQTCV + + + + L + F
Sbjct: 133 KNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY- 191
Query: 328 GHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVP 387
G S G +IN+ +++ A + G V GG+ E + APTVL V
Sbjct: 192 GDDPQSSPNLGRIINQKQFQRLRALL------GCGRVAIGGQSNE-SDRYIAPTVLVDVQ 244
Query: 388 STAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGM 447
T V ++E FGP+ ++ +++E + + N E LA Y FS + V + E +G
Sbjct: 245 ETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLERTSSGS 304
Query: 448 VSCNTGL--FSECTIPFGGVKESGFGR 472
N G S ++PFGGV SG GR
Sbjct: 305 FGGNEGFTYISLLSVPFGGVGHSGMGR 331
>Hs20546780 [C] KOG2450 Aldehyde dehydrogenase
Length = 637
Score = 120 bits (302), Expect = 4e-27
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 16/332 (4%)
Query: 154 VGVCGIICPWNFPSAMITRKAGAALAAGCTVV--VKPDSQTPLSALALAHLAEKAGFPKG 211
+GV G+I P F + + ALA GCTVV V P S PL LA LA + G G
Sbjct: 1 MGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPL---LLAQLAGELGPFPG 57
Query: 212 VFNVVL-TATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAP 270
+ NV+ A+ P L P ++K++F G+ G+ L + A +L LG +
Sbjct: 58 ILNVLSGPASLVP----ILASQPGIRKVAFCGAPEEGRALRRSLAGECAELGLALGTESL 113
Query: 271 VIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHG 330
+++ D AD++ AV + + + G + R+ +Q ++ D +L +++ G G
Sbjct: 114 LLLTDTADVDSAVEGVVDAAWSDRGPGGL---RLLIQESVWDEAMRRLQERMGRLRSGRG 170
Query: 331 LDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTA 390
LD G A V+ V++A +GA+ AG +P P FY PT++S++P +
Sbjct: 171 LDGAVDMGAR-GAAACDLVQRFVREAQSQGAQVFQAGD-VPSERP-FYPPTLVSNLPPAS 227
Query: 391 VVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSC 450
+ E P+ PF T +E + AN T G ++ V+S+ + + L+ G V
Sbjct: 228 PCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWI 287
Query: 451 NTGLFSECTIPFGGVKESGFGREGSLHGIEDY 482
N + ++P GG KESG G G+ +Y
Sbjct: 288 NAHGLRDPSVPTGGCKESGCSWHGGPDGLYEY 319
Score = 59.3 bits (142), Expect = 1e-08
Identities = 55/209 (26%), Positives = 89/209 (42%), Gaps = 5/209 (2%)
Query: 9 PEFKNSDLIRKGAFVDGQWLETASETFNVTDPATLEVIATLPDQSIEVIHEAIDSAAEAF 68
PE S G FV G++ + + ++ + + + + I A+++A +AF
Sbjct: 353 PEIGPSPAPPYGLFVGGRFQAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAF 412
Query: 69 RLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQGEVKYAASYFE-WYA 127
+ +P R+ L L + LA + G L A+ EV+ +A W A
Sbjct: 413 PGWAGQSPGARAALLWALAAALERRKSTLASRLE-RQGAELKAAEAEVELSARRLRAWGA 471
Query: 128 EEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVK 187
V+ G T+Q +R+P+GV ++CP +P ALA G TVV+
Sbjct: 472 R--VQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMV 529
Query: 188 PDSQTPLSALALAHLAEKAGFPKGVFNVV 216
P + PL AL + FP G+ NVV
Sbjct: 530 PSAACPLLALEVCQDMATV-FPAGLANVV 557
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 109 bits (272), Expect = 1e-23
Identities = 105/396 (26%), Positives = 171/396 (42%), Gaps = 21/396 (5%)
Query: 106 GKALSEAQGEVKYAAS---YFEWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICP 162
G+ + Q E+ AA +F + A+ AV + G S + R G I P
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISP 209
Query: 163 WNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRT 222
+NF +A+ AGA G V+ KP L++ A+ + +AG P + V
Sbjct: 210 FNF-TAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFV--PADG 266
Query: 223 PEFGLALCESPKVKKISFTGSTNVGKILMKQSAS------TMKKLSFELGGNAPVIVFDD 276
P FG + S + I+FTGS K L KQ A T +L+ E GG V
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 277 ADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGH-GLDSKT 335
AD+E V+ T+ S F GQ C +R+YV ++ +L ++ + +G D T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGT 386
Query: 336 THGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKD 395
+I+ + +++ ++ A + T++AGG+ + F P ++ + K+
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 396 ETFGPLCA--LIPFDTMEEVVGYAND-TELGLASYVFSKNIDTVYTVAEALETGMVSCNT 452
E FGP+ + + P D +E + + T GL VFS++ D V + L +
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 453 GLFSECTI----PFGGVKESGFG-REGSLHGIEDYT 483
S +I PFGG + SG + G H I +T
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWT 542
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 102 bits (254), Expect = 1e-21
Identities = 106/405 (26%), Positives = 172/405 (42%), Gaps = 28/405 (6%)
Query: 106 GKALSEAQGEVKYAASYFEW-----YAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGII 160
G++ + Q E+ AA ++ Y + V Y + + + R G +
Sbjct: 159 GQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAAV 218
Query: 161 CPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTAT 220
P+NF + AL G V+ KP LS + + +AG P GV N V
Sbjct: 219 SPFNFTAIGGNLSYTPALM-GNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFV--PA 275
Query: 221 RTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMK------KLSFELGGNAPVIVF 274
P FG + SP + I+FTGS L KQ + + +L+ E GG +
Sbjct: 276 DGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIH 335
Query: 275 DDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSK 334
AD+E VT TI S F GQ C +R+YV ++ E L + + IG D
Sbjct: 336 ASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQDFS 395
Query: 335 TTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPT-VLSHVPSTAVVN 393
+ +I++ A K++ +++ A + ++AGG + F PT VLS P ++
Sbjct: 396 SFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMT 455
Query: 394 KDETFGPLCALIPF---DTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSC 450
+E FGP+ ++ + D +E + T+ L VF ++ D V + E M +
Sbjct: 456 -EEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQ--EFKMAAG 512
Query: 451 NTGLFSECT------IPFGGVKESGFG-REGSLHGIEDYTVIKTI 488
N + + T PFGG + SG + G H I +T ++I
Sbjct: 513 NFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSI 557
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 100 bits (249), Expect = 5e-21
Identities = 109/438 (24%), Positives = 182/438 (40%), Gaps = 33/438 (7%)
Query: 55 EVIHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQG 114
E I EAID A +A +++ K R+ L +L T G+ + Q
Sbjct: 100 EQIQEAIDVALQARGAWERKPLKERAEILLRAADLAAGKYRMKLNASTML-GQGKNIIQA 158
Query: 115 EVKYAASYFEWYAEEAV--------RMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFP 166
E+ A +++ AV T I N R G I P+NF
Sbjct: 159 EIDAACELIDFFRFNAVFAMELEHYEPISTKITKNTMQFRGME-----GFVAAIAPFNFT 213
Query: 167 SAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFG 226
+ AL G + KP + LS + L E+AG P G+ + + + P FG
Sbjct: 214 AIGGNLPTAPALM-GNVSLWKPSNTAVLSNYIIYELLEEAGMPPGILSFL--PSDGPVFG 270
Query: 227 LALCESPKVKKISFTGSTNVGKILMKQSAS------TMKKLSFELGGNAPVIVFDDADLE 280
+ SP + ++FTGS K + ++ A T KL E GG V A ++
Sbjct: 271 DVITASPHLSAVNFTGSVPTFKTIWRKVAENLDNYVTFPKLIGECGGKNFHFVHPSAHVD 330
Query: 281 QAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCL 340
T S + GQ C +R+Y ++I EK++ E +G D +
Sbjct: 331 AVAAGTARSAWEYSGQKCSACSRMYAPKSIWPKILEKISAIHKEIKLGDVRDGSVFLSAV 390
Query: 341 INENAIKKVEAHVKDALEKGA--KTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETF 398
I++ A +++A++ D + GA VV GG+ + F PT+++ + + +E F
Sbjct: 391 IDDKAFARLKAYI-DFAKTGADGANVVLGGKCDDKTGYFIEPTLITVTDPKSKLLTEEMF 449
Query: 399 GPLCALIPFD--TMEEVVGYAND-TELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLF 455
GP+ ++ ++ ++EV+ D T GL VFS++ + +Y + L + +
Sbjct: 450 GPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFSQDKEFLYRARDVLRDAVGNMYLNDK 509
Query: 456 SECTI----PFGGVKESG 469
S +I PFGG + SG
Sbjct: 510 STGSIVGQQPFGGSRLSG 527
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 98.2 bits (243), Expect = 2e-20
Identities = 74/299 (24%), Positives = 127/299 (41%), Gaps = 13/299 (4%)
Query: 153 PVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGV 212
P GV +I WN+P ++ +A+AAG VV+KP A +A + PK +
Sbjct: 104 PFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADV-----IPKYL 158
Query: 213 FNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVI 272
N A + + I +TGST VGKI+ + + + ELGG +P
Sbjct: 159 DNDCYPVVCGGPSETAELLNQRFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCY 218
Query: 273 VFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLD 332
+ D+ AV + + K GQTC+ + I + + + F + AK V + G +
Sbjct: 219 IDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVE-AKDVLKEWYGENIQ 277
Query: 333 SKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVV 392
S +IN N +++ L K + V G + F PT+L V T +
Sbjct: 278 SSPDLSRVINANNFQRLL-----GLMKSGRVAVGGNY--DASERFIEPTILVDVKETDPI 330
Query: 393 NKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCN 451
++E FGP+ + ++ + + + N E L Y+F+ + ++G + N
Sbjct: 331 MEEEIFGPILPIFNVESAYDAIKFINARESPLVLYIFTPTAEVQNLFINGTQSGGLCVN 389
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 90.9 bits (224), Expect = 4e-18
Identities = 84/329 (25%), Positives = 144/329 (43%), Gaps = 24/329 (7%)
Query: 160 ICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTA 219
I P+NF +A+ A A L G V++KP LS+ + + +AG P G +
Sbjct: 189 ITPFNF-TAIAGNLAAAPLLMGNVVLMKPSDHAVLSSYIVYQIFREAGLPAGALQFI--P 245
Query: 220 TRTPEFGLALCESPKVKKISFTGST--------NVGKILMKQSASTMKKLSFELGGNAPV 271
E P+ + FTGST +G+ + T K+ E GG
Sbjct: 246 GDAVEVSKVCFNHPEFAGLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGKNFH 305
Query: 272 IVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDS-FAEKLAKQVNEFVIGHG 330
+V A+++ AV + + F GQ C +R+YV + ++ F ++L KQV +G
Sbjct: 306 LVHSSAEIKSAVVNAVRAAFEYQGQKCSALSRLYVSKYAWENGFRDELTKQVKSLKVGAP 365
Query: 331 L-DSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPST 389
L D G +I++ + K++ ++ A V+AGG+ + F PTVL
Sbjct: 366 LTDFANFVGPVIHQASFNKLKKVLESAASDSEIEVLAGGKADDSEGFFVEPTVLLSKNPK 425
Query: 390 AVVNKDETFGPLCALIPF--DTMEEVVGYAN-DTELGLASYVFSKNIDTVYTVAEALETG 446
+ +E FGP+ ++ + D ++ V + T GL +F+++ V + + L
Sbjct: 426 HDIFVNELFGPVLSVYVYEDDNLDAVCDLIDTTTPYGLTGSIFAQDRVVVRKLTDRLRN- 484
Query: 447 MVSCNTGLFSECT------IPFGGVKESG 469
+ N + +CT PFGG + SG
Sbjct: 485 -AAGNFYINDKCTGAVVGEQPFGGARASG 512
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 90.5 bits (223), Expect = 5e-18
Identities = 94/457 (20%), Positives = 179/457 (38%), Gaps = 86/457 (18%)
Query: 55 EVIHEAIDSAAEAFRLFKKTTPKTRSTWLRNLYNLMMENVDDLAKIITWENGKALSEAQG 114
E + E++ E F + + K R + +Y ++ +N D + + + GK +EA
Sbjct: 6 ETVEESLREMRETFASGRTRSLKWRKAQIGAIYEMVKDNEDKICNALFQDLGKHSTEAFR 65
Query: 115 E--------VKYAASYFEWYAEEAVRMYGTTIQPNNGSNRAFTVRQPVGVCGIICPWNFP 166
+ A + + +A P G + +P G ++ WNFP
Sbjct: 66 DELGVVLRTATVAINCLDKWAVPKHSKLPLLFYPAKGK----VISEPYGTVLVLSSWNFP 121
Query: 167 SAMITRKAGAALAAGCTVVVKPDSQTPLSALALA-----HLAEKAGFPKGVFNVVLTATR 221
++ A+AAG TV++K +P ++ LA +L KA +
Sbjct: 122 ISLSLDPLIGAIAAGNTVLLKSSELSPNASAFLAKTIPAYLDTKA---------IKVIEG 172
Query: 222 TPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQ 281
P+ L + + KI FTGS +G+I+M +A + ++ ELG
Sbjct: 173 GPDVATILLQH-QWDKIFFTGSPKIGRIIMAAAAQHLTPVTLELG--------------- 216
Query: 282 AVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCL- 340
G++C+ + + ++++ + + L + F + +S GCL
Sbjct: 217 -------------GKSCISVDYVLIEKSFAPTLIDMLKPTIKSFFGENPKES----GCLS 259
Query: 341 --INENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETF 398
N++ ++++ + D PT+L P + + +E F
Sbjct: 260 RIANKHHVQRLSRLLSDP----------------------RPTILLDPPLDSEIMNEEIF 297
Query: 399 GPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSEC 458
GP+ +I ++E +G N LA Y F+ + + + +G V+ N +
Sbjct: 298 GPILPIITVRDIQESIGIINTKPKPLAIYAFTNDENLKTRILSETSSGSVTFNDVMIQYM 357
Query: 459 --TIPFGGVKESGFGREGSLHGIEDYTVIKTITIGNL 493
+PFGGV ESG GR + + ++ K I G+L
Sbjct: 358 CDALPFGGVGESGIGRYHGKYSFDCFSHEKAIMEGSL 394
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 83.2 bits (204), Expect = 8e-16
Identities = 114/496 (22%), Positives = 206/496 (40%), Gaps = 46/496 (9%)
Query: 10 EFKNSDLIRKGAFVDGQWLETASET--FNVTDPAT-LEVIATLPDQSIEVIHEAIDSAAE 66
+FK+S L ++G+ + +E F T+PA +V+A + + + + A+ +A +
Sbjct: 53 KFKSSSL-EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKD 111
Query: 67 AFRLFKKTTPKTRSTWLRNLYNLMMENVD-DLAKIITWENGKALSEAQGE-VKYAASYFE 124
A + + RS +L+ D+ GK + +A+ + + + +F
Sbjct: 112 AKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFR 171
Query: 125 WYAEEAVRMYGTT-IQPNNGSNRAFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCT 183
+Y + A +Y ++ +G+ R G + P+NF +A+ GA G T
Sbjct: 172 YYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNF-TAIAANLIGAPALMGNT 230
Query: 184 VVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATRTPEFGLALCESPKVKK----IS 239
VV KP LS L + E+AG PKGV N + P + + + K +
Sbjct: 231 VVWKPSQTAALSNYLLMTVLEEAGLPKGVINFI------PGDPVQVTDQVLADKDFGALH 284
Query: 240 FTGSTNVGKILMKQSASTM--------KKLSFELGGNAPVIVFDDADLEQAVTQTILSKF 291
FTGSTNV K L + S + ++ E GG +V A++ AV TI F
Sbjct: 285 FTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTF 344
Query: 292 RGLGQTCVCANRIYVQRTIIDSF---------AEKLAKQVNEFVIGHGLDSKTTHGCLIN 342
GQ C A+R+Y+ + + F ++ + G + + G +I+
Sbjct: 345 EFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIH 404
Query: 343 ENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLC 402
E + K+ ++DA + ++ GG+ + F PTV+ E FGP+
Sbjct: 405 EQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPIL 464
Query: 403 ALIPFDTME--EVVGYANDT-ELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECT 459
+ + E E+ ++T + L +F+K+ + E L+ + N + +CT
Sbjct: 465 TVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLK--FSAGNFYINDKCT 522
Query: 460 IP------FGGVKESG 469
FGG + SG
Sbjct: 523 GAVVSQQWFGGARMSG 538
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 77.0 bits (188), Expect = 6e-14
Identities = 60/205 (29%), Positives = 92/205 (44%), Gaps = 6/205 (2%)
Query: 147 AFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKA 206
AF ++P G+ II PWN+P + ALAAG VV+KP + LA + +
Sbjct: 61 AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY 120
Query: 207 GFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMKKLSFELG 266
+ F VVL + E G L + I FTGS VGKI+M +A + ++ ELG
Sbjct: 121 -VDQSCFAVVLGGPQ--ETGQLL--EHRFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELG 175
Query: 267 GNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFV 326
G P V D+ D + + ++ GQTCV + + + + L + F
Sbjct: 176 GKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRF- 234
Query: 327 IGHGLDSKTTHGCLINENAIKKVEA 351
G S G +IN+ +++ A
Sbjct: 235 YGDDPQSSPNLGRIINQKQFQRLRA 259
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 69.7 bits (169), Expect = 9e-12
Identities = 80/312 (25%), Positives = 136/312 (42%), Gaps = 35/312 (11%)
Query: 177 ALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFNVVLTATR--TPEFGLALCESPK 234
A+AAG VV+KP P ++ LA L F + + N + PE L + K
Sbjct: 196 AIAAGNAVVLKPSEIAPAASSLLAKL-----FSEYLDNTTIRVIEGGVPETTALLDQ--K 248
Query: 235 VKKISFTGSTNVGKILMKQSASTMKKLSFELGGNAPVIVFDDADLEQAVTQTILSKFR-G 293
KI FT + +L+K + + V+++ L+ A + I K+
Sbjct: 249 WDKIFFTDLS----LLLKHKIVKFRSHTLI------VVLW----LKVAARRIIAGKWACN 294
Query: 294 LGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHV 353
GQ C+ + + + + L ++ F + L+SK ++N K++E+ +
Sbjct: 295 SGQACIGVDYVITTKDFASKLIDALKTELETFFGQNALESKDLSR-IVNSFHFKRLESML 353
Query: 354 KDALEKG-AKTVVAGGRLPELGPNFYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEE 412
K E G A +V GGR+ E +PT+L VP + + ++E FGPL +I +E+
Sbjct: 354 K---ENGVANKIVHGGRITEDKLKI-SPTILLDVPEASSMMQEEIFGPLLPIITVQKIED 409
Query: 413 VVGYANDTELGLASYVFSKNIDTVYTVAEALETGMVSCNTGLFSECT--IPFGGVKESGF 470
LA+Y+F+ N + + + G ++ N + +PFGGV ESG
Sbjct: 410 GFQVIRSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGVGESGI 469
Query: 471 GREGSLHGIEDY 482
G+ HG Y
Sbjct: 470 ---GAYHGKFSY 478
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 67.4 bits (163), Expect = 5e-11
Identities = 67/307 (21%), Positives = 126/307 (40%), Gaps = 13/307 (4%)
Query: 155 GVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKAGFPKGVFN 214
G I P+NF + + A G +V+ KP LS + +AG P GV N
Sbjct: 235 GFVAAISPFNF-TGIAANLAYTPALMGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVN 293
Query: 215 VVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMK------KLSFELGGN 268
V T F + + PK+ I+FTG++ V K+L + A + +L E GG
Sbjct: 294 FVPAEETT--FASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGK 351
Query: 269 APVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAKQVNEFVIG 328
V A+ E AV TI + F GQ C + +YV ++ + + ++ ++
Sbjct: 352 NFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVV 411
Query: 329 HGLDSKTTHGC--LINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAPTVLSHV 386
+ C +IN A ++ ++ + + ++ GG + + PTV+
Sbjct: 412 RQDATYCDSFCSAVINRRAYDRIYMWLRYIDQSPSCQILVGGSCDKRRGYYVDPTVVLVK 471
Query: 387 PSTAVVNKDETFGPLCA--LIPFDTMEEVVGYANDTELGLASYVFSKNIDTVYTVAEALE 444
++ ++E P+ + P ++E + GL VF+++ + + +A
Sbjct: 472 DLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQDQNFIEEAYDAFR 531
Query: 445 TGMVSCN 451
+ + N
Sbjct: 532 VNVGNLN 538
>Hs20479244 [C] KOG2450 Aldehyde dehydrogenase
Length = 292
Score = 66.6 bits (161), Expect = 8e-11
Identities = 48/166 (28%), Positives = 79/166 (46%), Gaps = 3/166 (1%)
Query: 317 KLAKQVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPN 376
+L +++ G GLD G A V+ V++A +GA+ AG +P P
Sbjct: 3 RLQERMGRLRSGRGLDGAVDMGAR-GAAACDLVQRFVREAQSQGAQVFQAGD-VPSERP- 59
Query: 377 FYAPTVLSHVPSTAVVNKDETFGPLCALIPFDTMEEVVGYANDTELGLASYVFSKNIDTV 436
FY PT++S++P + + E P+ PF T +E + AN T G ++ V+S+ +
Sbjct: 60 FYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQA 119
Query: 437 YTVAEALETGMVSCNTGLFSECTIPFGGVKESGFGREGSLHGIEDY 482
+ L+ G V N + ++P GG KESG G G+ +Y
Sbjct: 120 LELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEY 165
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 50.1 bits (118), Expect = 8e-06
Identities = 68/338 (20%), Positives = 132/338 (38%), Gaps = 23/338 (6%)
Query: 147 AFTVRQPVGVCGIICPWNFPSAMITRKAGAALAAGCTVVVKPDSQTPLSALALAHLAEKA 206
+F +R G + P+ A+ + A G TV+ P + + + ++A
Sbjct: 194 SFHLRPMDGFVAALAPFE-SVALSSSLALCPALMGNTVLWNPSLEVAPVSYLIFRAFQEA 252
Query: 207 GFPKGVFNVVLTATRTPEFGLALCESPKVKKISFTGSTNVGKILMKQSASTMK------K 260
G P GV N V R F + ++ ++ S + + K + M+ +
Sbjct: 253 GLPSGVINFVPANERL--FLDTITDAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPR 310
Query: 261 LSFELGGNAPVIVFDDADLEQAVTQTILSKFRGLGQTCVCANRIYVQRTIIDSFAEKLAK 320
L E G V A +E V+ T+ + F GQ +R+YV ++ E+L +
Sbjct: 311 LVAECPGQNFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVE 370
Query: 321 QVNEFVIGHGLDSKTTHGCLINENAIKKVEAHVKDALEKGAKTVVAGGRLPELGPNFYAP 380
+ IG ++S+T G +++ N ++++ ++ + GG + F P
Sbjct: 371 ATEQLTIGDPIESETDIGAMVHINDFRRMQKLLQRTKN---MEQLCGGSCDDSTGRFVDP 427
Query: 381 TVLSHVPSTAVVNKDETFGPLCALIPF--DTMEEVVGY-ANDTELGLASYVFSKNIDTVY 437
T++ + + GP + + D+ E + AN + L+ +F+ + +
Sbjct: 428 TIVRVSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVIL 487
Query: 438 TVAEALETGMVSCNTGLFSECT------IPFGGVKESG 469
L M + N + CT PFGG + SG
Sbjct: 488 HCLNQLR--MSASNLYVNERCTGSTYGLTPFGGNRLSG 523
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,938,566
Number of Sequences: 60738
Number of extensions: 1206352
Number of successful extensions: 3071
Number of sequences better than 1.0e-05: 75
Number of HSP's better than 0.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2771
Number of HSP's gapped (non-prelim): 81
length of query: 497
length of database: 30,389,216
effective HSP length: 111
effective length of query: 386
effective length of database: 23,647,298
effective search space: 9127857028
effective search space used: 9127857028
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)