ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4589 good Z KOG2053 Cytoskeleton Mitochondrial inheritance and actin cytoskeleton organization protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4589 1578121 1575812 -770
(770 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL076w [Z] KOG2053 Mitochondrial inheritance and actin cytoskel... 424 e-118
SPBC1215.02c [Z] KOG2053 Mitochondrial inheritance and actin cyt... 62 3e-09
Hs22061926 [Z] KOG2053 Mitochondrial inheritance and actin cytos... 59 4e-08
>YOL076w [Z] KOG2053 Mitochondrial inheritance and actin cytoskeleton
organization protein
Length = 796
Score = 424 bits (1089), Expect = e-118
Identities = 267/794 (33%), Positives = 447/794 (55%), Gaps = 35/794 (4%)
Query: 7 QLFQLLDRELFKKASQFVASLQKRYPSATYYKVLEQYVKYRQSPAKYSFENGLKLILDAK 66
++ L+ R FK+ + LQK++P+A Y+K+LE YVK++QSP K+ + L+ K
Sbjct: 8 EILGLVSRSNFKQCYAKLGQLQKQFPNALYFKILETYVKFKQSPGKFDYNKLLEEPYGLK 67
Query: 67 SPP--SDAKSLSMCHRFLLELGFDTTSALEPYERAMMKYGNSETCYDWFLESLRDLNWRH 124
D +SL H F +ELG AL YER K+ + E Y WF+++L D N+
Sbjct: 68 GTTITGDTRSLEFLHNFFVELG-KYDEALHVYERGNFKFPSYELSYHWFMKALEDSNYNQ 126
Query: 125 LSKSSFQMPRVNEKSK--SRLFQFWNSIATVVWFQLDKDNINERELDLLPKLTYKLTSDL 182
+SK+S Q+ + ++ R + FWN+I+ + + ++ +++ + LL +L + DL
Sbjct: 127 MSKASLQLAKYSDSGNLPKRAYYFWNAISILAVSRFQENTLSDPKKILLSRLARQSLLDL 186
Query: 183 KPFENEQELIVFCKVCELFEDKSQEIVDEI--LKFWKHGTYLDLYLKNFLMGHLVKLDDY 240
KPF+N QE+IV+C V + +S+EI +EI + F T ++LYLKNF++ H L+
Sbjct: 187 KPFQNVQEIIVYCLVLDELFPQSREISEEIVAITFANFDTSVNLYLKNFILKHTKLLNSP 246
Query: 241 KLIWKHGISLLNN-LDDYGILQKIIDASYKLGKSFDELLEVLE--IKNTRNYILARVAAA 297
+ +++ L+ LDDY ++ +IDA+YKL KS DE+ + ++ + ++RN LAR+
Sbjct: 247 QKLFEVCSKLIEKGLDDYELITNLIDAAYKLSKSKDEVKQWIDENLGDSRNTRLARLKLD 306
Query: 298 KLYDDRL-DHYLFQFIEKYHDKPSCPIDL--HSLELNPVKIETMFSKLP---SGLIHDKA 351
+Y D + + L ++ KYH+KP C IDL +S +N ++++ SK LIH
Sbjct: 307 IMYTDSVSESSLSYYLSKYHNKPCCSIDLNHYSGHINIDMLKSIMSKYDPEDKDLIHHCN 366
Query: 352 VAQLFGKG-DNLELFLKHKESLSTKPKTDYSNCSYFILEIVKDLCQDSKVNLENVITSIS 410
+ +L G D++ + K K +L K TDYS+CS F+LEIVKD C+ + L++V+ I+
Sbjct: 367 ILELGLIGSDSINNYNKFKGTLEKKSVTDYSSCSTFLLEIVKDKCKKTNPELKDVLLCIT 426
Query: 411 LLEGYQAEDPFNYDTRVWLVLLYMYLGLPEKAIAHLETLNIKNVQNDLVNHWLFTRSSTF 470
+LE YQA+DP N+DT WL++LYMYLGL A H L IKNVQ D +++ +F+R ST
Sbjct: 427 ILENYQAKDPHNFDTMCWLIVLYMYLGLVPDAYFHFINLKIKNVQTDSLDYMIFSRFSTL 486
Query: 471 LPNKNYKYCQRSL-QPQAIY-SSLKNMSGFLVASFERRSWCKVPGIVEFYQRIFQSFTRW 528
PNK + ++ + +Y +SL N+ ++ +FER S+ K+ G++E ++ +S+TRW
Sbjct: 487 FPNKQSDFYSKTFHEHNNLYDTSLANLPRYIQVAFERNSYSKILGMLEMRDKLMKSYTRW 546
Query: 529 DAMVETLQMSRLLNEKKLDQYKPLIESLNTFGENNFHNENWSDNRDFDIFGTDDVTRFQT 588
+E LQ SRL N+K+ + L E + + ++SDNRDF I ++ +F
Sbjct: 547 TKTLENLQFSRLCNDKRGHLLQKLHEDWRSL--EMTQSVSFSDNRDFSIL-DENFAQFLN 603
Query: 589 ---VLAPIHVGTKWLKISITRELIFYSLTKNERNRFIDDTLVTTNDEELRELMSQH--EL 643
+L ++ + + +++ RELI +L E+ I L L EL++ + E+
Sbjct: 604 RGKILEYANLNEESIFLTLIRELIIEALPNGEKTEQISALLKKLPSINLEELLNNNLTEV 663
Query: 644 WTWQLIKLLYNSLETEAIDYKAMAMLIEQCPEISKSTWELNHSYLITLATLKSLDQMKRI 703
+ + + + E + + + + P +K W ++H+YL +ATLK+LD +KRI
Sbjct: 664 ESASFL-IFFEIYENNGKNLHDLISRLMKVPINAKQNWMVSHTYLTKMATLKTLDSLKRI 722
Query: 704 KDKSVKQLIKTKLKETRDTCVPMFKSYAD-MVQSVGN------GNKLLETVSYSKLTGDI 756
KDK +++LIK LKE R C +FK Y+ +VQ+ GN L E ++ +I
Sbjct: 723 KDKEIQKLIKNSLKELRSCCDDVFKGYSKALVQAYEELKKDECGNLLKELDVKAENVKNI 782
Query: 757 ATEITQMSKSIRNI 770
+ + KS+RN+
Sbjct: 783 KNSLLGIQKSVRNL 796
>SPBC1215.02c [Z] KOG2053 Mitochondrial inheritance and actin cytoskeleton
organization protein
Length = 811
Score = 62.4 bits (150), Expect = 3e-09
Identities = 128/633 (20%), Positives = 262/633 (41%), Gaps = 88/633 (13%)
Query: 96 YERAMMKYGNSE-TCYDWFLESLRDLNWRHLSKSSFQMPRVNEKSKSRLFQFWNSIATVV 154
+E+ + YG E +F S+R + H K++ ++ + SR W + +
Sbjct: 65 WEKFLQTYGKQEKNLLAYFKASIRIKSLSHQRKAAVELQK---NFPSRKHTLWVISSLYL 121
Query: 155 WFQLDKDNINERELDLLPKLTYKLTSDLKP---FENEQELIVFCKVCELFEDKSQEIVDE 211
+ ++ + +R L L + T KL + KP ++ +E ++ V L DK + +
Sbjct: 122 LSKKSENEVEQRLLKALAEKTAKLIFE-KPTGYIDSCEEFHLYLDVLLLVGDKDRALDAL 180
Query: 212 ILKFWKHGTYLDLYLKNFLMGHLVKLDDYKLIWKHGISLLNNLD-DYGILQKIIDASY-- 268
I + D L + L + ++ +SL + D+ + + ++D++
Sbjct: 181 IHQDADRFVDADADLLLRKLELLASCARWDSLFTFSLSLFQTGNTDWKVCKALLDSASND 240
Query: 269 --KLGKSFDELLEVLEIKNTRN--YILARVAAAKLYDDRLDHYLFQFIEKYHDKPSCPID 324
KL D +L+ L +T+ ++L A+A+ + + + L +I+K + KP D
Sbjct: 241 DSKLVPLKDCILKALSTSSTKRNLHLLWIEASARFFPEEHESALLGYIKKLYMKPIVFED 300
Query: 325 LHSLELNPVKIETMFSKLPSGLIHD-------KAVAQLFGKGDNLELFLKHKESLSTKPK 377
L L + ++ L + + D + V +L+ + L++ ES + +
Sbjct: 301 LRPYLLK-LNVDAQHRLLDAFKLADLGESNESQKVDKLYAEVLLLKIHFLLFESFTAESV 359
Query: 378 TDYSNCSY---------------------------------FILEIVKDLCQDSKVNLEN 404
DY + ++ E KDL K L
Sbjct: 360 VDYVRRCFVAFEKGLSLSKGLLPTDFTHGYEALLLAVHSLIYMWEGNKDLKPAEKQAL-- 417
Query: 405 VITSISLLEGYQAEDPFNYDTRVWLVLLYMYL--GLPEKAIAHLETLNIKNVQNDLVNHW 462
+ +I LLE N+ ++ L+ LY+ L G P A + +T++IK +QND ++H+
Sbjct: 418 IFDAICLLEKGITYSQHNFHLKLPLIRLYLLLDGGFPAAAKVY-DTMSIKQIQNDTLDHY 476
Query: 463 LFTRSSTFLPNK-NYKYCQRSLQPQAIYSSLKNMSGFLVA-SFERRSWCKVPGIVEFYQR 520
L TR++T+ P+ Y SL+ IY S + + +++ ++E ++ ++ + F R
Sbjct: 477 LLTRATTYYPSSVTSHYINSSLK---IYGSNEFETPEMISMAYEDGAYSQIEDMRNFRSR 533
Query: 521 IFQSFTRWDAMVETLQMSRLLNEKKLDQYKPLIESLNTFGENNFHNENWSDNRDFDIFGT 580
+ S + ++VE ++ L K QY P S DNRD +F
Sbjct: 534 LDHSTWKSISLVERARIHYLTAFKPPKQYLPKCSSP-------------KDNRDLKVFAD 580
Query: 581 DDVTRFQTVLAPIHVGTK----WLKIS-ITRELIFYSLTKNERNRFI----DDTLVTTND 631
+ TV + K W+ ++ I L+ S+ + + + + ++ N+
Sbjct: 581 YGSDKLPTVEESLRNSPKPDTLWIHLTVIGHSLVQDSIVNGDFEKAVLSAKEMEVLCENN 640
Query: 632 EELRELMSQHELWTWQLIKLLYNSLETEAIDYK 664
+ ++L S+ + LI+L S++ + DY+
Sbjct: 641 DLSKQLTSEEIVHMKLLIQLGLLSVKVKNGDYE 673
>Hs22061926 [Z] KOG2053 Mitochondrial inheritance and actin cytoskeleton
organization protein
Length = 852
Score = 58.5 bits (140), Expect = 4e-08
Identities = 84/351 (23%), Positives = 146/351 (40%), Gaps = 48/351 (13%)
Query: 305 DHYLFQFIEKYHDKPSCPIDLHS-LELNPVKIETMFSKLPSGLI------HDK------- 350
+ +FQ+ +K+ DKP C DL ++L P T F G++ DK
Sbjct: 229 EELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADI 288
Query: 351 -------AVAQL---------FGKGDNL----ELFLKHKESLS---TKPKTDYSNCSYFI 387
V QL K L EL L+++ L T KT+ Y+
Sbjct: 289 RALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKTCLKTELQFSDYYC 348
Query: 388 LEIVKDLCQDSKVNLEN--VITSISLLEGYQAEDPFNYDTRVWLVLLYMYLGLPEKAIAH 445
L V L + + V +++LLE P N ++ LV +Y LG E +
Sbjct: 349 LLAVHALIDVWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDL 408
Query: 446 LETLNIKNVQNDLVNHWLFTRSSTFLPNKNYKYCQRSLQPQAIYSSLKNMSGFLVASFER 505
+L+ K++Q+D + +L TR + L + + +S+ K+ S +++ +++
Sbjct: 409 YSSLDAKHIQHDTIG-YLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKY 467
Query: 506 RSWCKVPGIVEFYQRIFQSFTRWDAMVETLQMSRLLNEKKLDQYKPLIESLNTF-GENNF 564
++ K+P + F R+ S E + + LL I+S+N E++
Sbjct: 468 GAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDI 527
Query: 565 HNENWSDNRDFDIFGT-----DDVTRFQTVLAPIHVGTKWLKI-SITRELI 609
E+ DNRD ++F + DV+ L+ + T WL+I S+T LI
Sbjct: 528 PWEDLRDNRDLNVFFSWDPKDRDVSEEHKKLS-LEEETLWLRIRSLTLRLI 577
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,099,089
Number of Sequences: 60738
Number of extensions: 2040317
Number of successful extensions: 5825
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 5811
Number of HSP's gapped (non-prelim): 5
length of query: 770
length of database: 30,389,216
effective HSP length: 114
effective length of query: 656
effective length of database: 23,465,084
effective search space: 15393095104
effective search space used: 15393095104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)