ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4674 good ABO KOG1446 Chromatin structure and dynamics Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2
r_klactV4674 good ABO KOG1446 Posttranslational modification, protein turnover, chaperones Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2
r_klactV4674 good ABO KOG1446 RNA processing and modification Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4674 1608371 1609348 326
(326 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL018w [ABO] KOG1446 Histone H3 (Lys4) methyltransferase comple... 495 e-140
SPBC18H10.06c [ABO] KOG1446 Histone H3 (Lys4) methyltransferase ... 189 4e-48
SPAC824.04 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase com... 181 1e-45
7297395 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase comple... 176 5e-44
Hs17434629 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase com... 164 2e-40
CE04150 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase comple... 146 5e-35
At5g14530 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase comp... 144 2e-34
At5g66240 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase comp... 135 6e-32
CE04149 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase comple... 102 6e-22
7295945 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase comple... 94 2e-19
7290331 [R] KOG0266 WD40 repeat-containing protein 67 4e-11
Hs16554627 [R] KOG0266 WD40 repeat-containing protein 66 6e-11
CE06574 [R] KOG0266 WD40 repeat-containing protein 65 1e-10
CE00901 [R] KOG0266 WD40 repeat-containing protein 61 3e-09
SPBC354.03 [R] KOG0266 WD40 repeat-containing protein 60 6e-09
Hs4826956 [A] KOG0291 WD40-repeat-containing subunit of the 18S ... 58 2e-08
Hs9506645 [R] KOG0266 WD40 repeat-containing protein 57 3e-08
7302720 [R] KOG0266 WD40 repeat-containing protein 57 3e-08
SPBC713.04c [A] KOG0291 WD40-repeat-containing subunit of the 18... 55 1e-07
7303694 [A] KOG0291 WD40-repeat-containing subunit of the 18S rR... 55 1e-07
At4g02730 [R] KOG0266 WD40 repeat-containing protein 54 2e-07
Hs7657439 [K] KOG0263 Transcription initiation factor TFIID subu... 53 5e-07
YCR057c [A] KOG0291 WD40-repeat-containing subunit of the 18S rR... 53 7e-07
Hs13376840 [R] KOG4155 FOG: WD40 repeat 52 9e-07
At3g49660 [R] KOG0266 WD40 repeat-containing protein 51 2e-06
Hs19705568 [R] KOG0288 WD40 repeat protein TipD 50 3e-06
Hs14150114 [S] KOG0316 Conserved WD40 repeat-containing protein 50 6e-06
7296695 [A] KOG0284 Polyadenylation factor I complex subunit PFS2 49 1e-05
>YKL018w [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 329
Score = 495 bits (1275), Expect = e-140
Identities = 232/327 (70%), Positives = 283/327 (85%), Gaps = 2/327 (0%)
Query: 2 TVSISKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFL 61
TVSI+K NLL+F+ VKSF+ +K+ GP+TS+ FDD+GQ+LLT++++D M LY A +C+FL
Sbjct: 3 TVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLTSSSNDTMQLYSATNCKFL 62
Query: 62 NTIASKKYGCHSAKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMS 121
+TIASKKYGCHSA FTHAQ+ECIYSSTMK+FDI++LNLETN YLRYF GHGALV+D++M+
Sbjct: 63 DTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLETNQYLRYFSGHGALVNDLKMN 122
Query: 122 PLDDTFLSASYDESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYN 181
P++DTFLS+SYDESVRLWDL+ SK Q +IPSLVP CIAYDPSGLVFA+GNPEN E+GLYN
Sbjct: 123 PVNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIAYDPSGLVFALGNPENFEIGLYN 182
Query: 182 VKHLKAGPFLVINV-DPSFDQWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGT 240
+K ++ GPFL+I + D +F QWNKLEFSN+GKYLL+ SS GKHLI D+F G QLFEL GT
Sbjct: 183 LKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLVGSSIGKHLIFDAFTGQQLFELIGT 242
Query: 241 KPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWNHADFISGRTLKPQGFINAAPN-TC 299
+ FP+REF+DSGSA FTPDG LGTDY G+IAIWNH+D IS + L+PQGFI + TC
Sbjct: 243 RAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAIWNHSDSISNKVLRPQGFIPCVSHETC 302
Query: 300 PRTIAFNPKYSMFVTADETVDFYVYNE 326
PR+IAFNPKYSMFVTADETVDFYVY+E
Sbjct: 303 PRSIAFNPKYSMFVTADETVDFYVYDE 329
>SPBC18H10.06c [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 357
Score = 189 bits (481), Expect = 4e-48
Identities = 118/356 (33%), Positives = 183/356 (51%), Gaps = 37/356 (10%)
Query: 2 TVSISKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFL 61
TVSI+ L +P K + + +G ITS++FDD G+ L + D + LY+ +S +F+
Sbjct: 3 TVSITFDLLSSMQPRKWLK-NQNFVGEITSLSFDDSGELCLASCTDDTLQLYNCISGKFV 61
Query: 62 NTIASKKYGCHSAKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMS 121
++ASKKYG H +FTH + I++ST + +R+L++ TN YLRYF GH V+ I +S
Sbjct: 62 KSLASKKYGAHLGRFTHHSNSLIHASTKEDNTVRYLDVVTNRYLRYFPGHKQTVTSIDVS 121
Query: 122 PLDDTFLSASYDESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYN 181
P D+TFLSAS D ++RLWDLRS Q L+ P A+D +GL+FA + +++ LYN
Sbjct: 122 PADETFLSASLDNTIRLWDLRSPNCQGLLNVSSPVVAAFDATGLIFASVSERKYKISLYN 181
Query: 182 VKHLKAGPF--LVINVDPSFDQWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSG 239
+K A PF + + P + +EFS DGKYLLL + H ++D++ G++L +
Sbjct: 182 IKSFDARPFQDIPLTFLPPHVRIANVEFSTDGKYLLLTTGNDFHYVIDAYSGSELLRVPS 241
Query: 240 TKPFPLRE--FMDSGSATFTPDGRITLGTDYTGKIAIWN--------HADFI-------- 281
++ SA +PD + + + ++ ++D I
Sbjct: 242 KVSTKTQDGNLTYYASACMSPDSKFLFTSYDNEHLCMYQLPELKQTVNSDHIVNSFTEMG 301
Query: 282 ---------SGRTLKPQGFI------NAAPNTCPRTIAFNPKYSMFVTADETVDFY 322
S T P I N P T P + FNP++S VTA V F+
Sbjct: 302 LASTTPTSNSHSTENPLAIIPSSTSKNLLPET-PSIVRFNPRFSQLVTAHSGVIFW 356
>SPAC824.04 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 341
Score = 181 bits (460), Expect = 1e-45
Identities = 107/333 (32%), Positives = 175/333 (52%), Gaps = 24/333 (7%)
Query: 10 LLRFEPVKSFRVSDKELGP-ITSVTFDDHGQYLLTA-TASDNMHLYDAVSCRFLNTIASK 67
L +P +SFR D LG I S+ + D G+Y+ T +A D + +YDA+ + ++TI
Sbjct: 6 LSSLKPAQSFR--DNSLGSFINSIDYSDSGEYVATTCSADDTVQIYDALDPKQVHTITCF 63
Query: 68 KYGCHSAKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTF 127
+ G A+FTH + S+T + DI+++++ N + YF GH +VS I++SP++D F
Sbjct: 64 ETGIEVARFTHHDHNLLLSTTKGNKDIQYVSIYDNKRISYFSGHTDIVSSIEVSPIEDQF 123
Query: 128 LSASYDESVRLWDLRSSK---AQALIPSL-VPTCIAYDPSGLVFAIGNPENHEVGLYNVK 183
+S + D++++LW + S +PSL +P AYDP+GLVFA+ + LY+V+
Sbjct: 124 VSTANDKTLKLWKMNQSSRCLGNLDLPSLGIP---AYDPTGLVFAVACHSLSRIFLYDVR 180
Query: 184 HLKAGPFLVINVD-----------PSFDQWNKLEFSNDGKYLLLASSAGKHLIMDSFDGT 232
+ + PF +D P +W +EFSNDGK +LL++ A H I+D+F G
Sbjct: 181 NYGSDPFSTFTIDDSRYLSRFSFPPMMPEWKHMEFSNDGKCILLSTRANVHYILDAFSGD 240
Query: 233 QLFELSGTKPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWN--HADFISGRTLKPQG 290
L L + P GS TF P G +G+ + +WN H G+T P+
Sbjct: 241 VLSRLEDFQELPFSNNFHGGSTTFVPQGNFVIGSADDRTLNVWNLRHTFHHKGKTRPPEH 300
Query: 291 FINAAPNTCPRTIAFNPKYSMFVTADETVDFYV 323
I + P + +NP+Y +TA + F++
Sbjct: 301 RIVSQSIINPGLVKYNPRYDQLLTAGSQLVFWL 333
>7297395 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 317
Score = 176 bits (445), Expect = 5e-44
Identities = 109/327 (33%), Positives = 172/327 (52%), Gaps = 21/327 (6%)
Query: 1 MTVSISKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRF 60
M + + S + F+ K FR + + I ++ F +G++L++ + D + +YD
Sbjct: 1 MKIKLIDSVVRSFKVAKIFRENTDK---INAIDFAPNGEHLISCSEDDQIVIYDCEKGTQ 57
Query: 61 LNTIASKKYGCHSAKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQM 120
T+ SKKYG FTHA + I+SST IR+L+L N YLRYF GH V + +
Sbjct: 58 SRTVNSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCI 117
Query: 121 SPLDDTFLSASYDESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLY 180
SP++DTFLS S D+++RLWDLRS Q L+ AYDP GL+FA G + + LY
Sbjct: 118 SPVEDTFLSGSLDKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAG-VNSESIKLY 176
Query: 181 NVKHLKAGPFLVINVDPSFD-QWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSG 239
+++ GPF+ ++ + W L+FS DGK +L++++ ++D+F GT L +G
Sbjct: 177 DLRSFDKGPFVTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTG 236
Query: 240 ---TKPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWNHADFISGRTLKPQGFINAAP 296
K P+ A+F+PD + G++ IWN AD +G + + P
Sbjct: 237 YPNNKGIPI-------EASFSPDSQFIFSGSTDGRVHIWN-AD--TGNKVSVLNGDHPGP 286
Query: 297 NTCPRTIAFNPKYSMFVTADETVDFYV 323
C + FNPKY M +A + F++
Sbjct: 287 VQC---VQFNPKYMMLASACTNMAFWL 310
>Hs17434629 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 315
Score = 164 bits (414), Expect = 2e-40
Identities = 101/315 (32%), Positives = 164/315 (52%), Gaps = 21/315 (6%)
Query: 16 VKSFRVSD---KELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCH 72
++SFRV+ + I F +GQ +++++ D++ LYD + T+ SKKYG
Sbjct: 8 LRSFRVARVFCENSDKINCFDFSPNGQTVISSSNDDSIVLYDCQEGKPKRTLYSKKYGVD 67
Query: 73 SAKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASY 132
++TH + +YSS IR+L+L N Y+RYF GH V + MSP+DD F+S S
Sbjct: 68 LIRYTHEANTAVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDIFISGSL 127
Query: 133 DESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLV 192
D+++RLWDLR+ Q L+ ++DP GL+ A G + V LY+++ GPF
Sbjct: 128 DKTIRLWDLRAPNCQGLMSLQGKPVCSFDPEGLILAAG-VNSEMVKLYDLRSFDKGPFTT 186
Query: 193 INVDPSFD-QWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSG---TKPFPLREF 248
+ + +W L+FSNDGK +L++++ ++D+F G + G +K L
Sbjct: 187 FRMQCNRTCEWTGLKFSNDGKVILISTNGSFISLIDAFKGVVMHTFEGYANSKAVTL--- 243
Query: 249 MDSGSATFTPDGRITLGTDYTGKIAIWNHADFISGRTLKPQGFINAAPNTCPRTIAFNPK 308
A+FTPD + + GKI +WN I L + + P TC + FNPK
Sbjct: 244 ----EASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGK---HTGPITC---LQFNPK 293
Query: 309 YSMFVTADETVDFYV 323
+ F +A ++ F++
Sbjct: 294 FMTFASACSSMVFWL 308
>CE04150 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 326
Score = 146 bits (368), Expect = 5e-35
Identities = 97/320 (30%), Positives = 161/320 (50%), Gaps = 24/320 (7%)
Query: 3 VSISKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLN 62
V I+ +L + P K + + S+++ G +++ +T D+M LYD +
Sbjct: 6 VEITAESLAKLTPAKQ---PNDTTTRVNSLSYGLKGDHMIMSTDDDSMFLYDMNTGLRSR 62
Query: 63 TIASKKYGCHSAKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSP 122
++ SKKYGC KF ++ ST IR+L+L N Y+RYFQGH LV+ I +SP
Sbjct: 63 SVNSKKYGCSHVKFASDSMCALHGSTKVDNTIRYLSLTDNKYIRYFQGHDKLVTGINVSP 122
Query: 123 LDDTFLSASYDESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYNV 182
+DD FLS + D+++RLWDL++ L+ +DP GL+FA G +N+ + LY++
Sbjct: 123 MDDMFLSVAEDKTIRLWDLKTHNCIGLMNLSATPIATFDPEGLLFAAG-LDNNIIKLYDL 181
Query: 183 KHLKAGPFLVINVDPSFD--QWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFEL--- 237
+ GPF + D +W + FS GKY+++ +++ + L++D+F G F L
Sbjct: 182 RSFDKGPFSSFGPLENEDNVEWTAMRFSPCGKYIMICTNSSQLLLVDAFTGLIKFTLEEH 241
Query: 238 SGTKPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWN-HADFISGRTLKPQGFINAAP 296
+ PL A+FTP+ + G I ++ I+ +TL P
Sbjct: 242 QNAQKIPL-------MASFTPESSHIMVGSSDGYIYFYDVETGEIALKTLAPNN------ 288
Query: 297 NTCPRTIAFNPKYSMFVTAD 316
TC F+P++ + TAD
Sbjct: 289 QTC-HIAEFSPQHFVAATAD 307
>At5g14530 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 330
Score = 144 bits (363), Expect = 2e-34
Identities = 99/306 (32%), Positives = 152/306 (49%), Gaps = 21/306 (6%)
Query: 27 GPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYS 86
G I SV F L+T++ D++ L+D + + L KK+G FTH S I S
Sbjct: 25 GKIHSVGFHRTDDLLVTSSEDDSLRLFDIANAKQLKITYHKKHGTDRVCFTHHPSSLICS 84
Query: 87 STMK----SFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLR 142
S +R+L++ N LRYF+GH V + MSP++D+F+S S D SVRLWDLR
Sbjct: 85 SRYNLESTGESLRYLSMYDNRILRYFKGHKDRVVSLCMSPINDSFMSGSLDRSVRLWDLR 144
Query: 143 SSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQW 202
+ Q ++ +AYD GLVFAI E V L++ + GPF V +
Sbjct: 145 VNACQGILHLRGRPAVAYDQQGLVFAIA-MEGGAVKLFDSRCYDKGPFDTFLVGGDTAEV 203
Query: 203 NKLEFSNDGKYLLLASSAGKHLIMDSFDGTQL--FELSGTKPFPLREFMDSGSATFTPDG 260
N ++FSNDGK +LL ++ ++D++ G + F L ++ P+ ATFTPDG
Sbjct: 204 NDIKFSNDGKSMLLTTTNNNIYVLDAYRGEKKCGFSLEPSQGTPI-------EATFTPDG 256
Query: 261 RITLGTDYTGKIAIWNHADFISGRTLKPQGFINAAPNTCPRTIAFNPKYSMFVTADETVD 320
+ L G + WN I + + N +C + + P+ +MFV A +
Sbjct: 257 KYVLSGSGDGTLHAWN----IENPSEVARWENNIGVVSC---LKWAPRRAMFVAASTVLT 309
Query: 321 FYVYNE 326
F++ N+
Sbjct: 310 FWIPND 315
>At5g66240 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 328
Score = 135 bits (341), Expect = 6e-32
Identities = 101/324 (31%), Positives = 153/324 (47%), Gaps = 17/324 (5%)
Query: 1 MTVSISKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRF 60
+++ +S+ + EP FR + I+S+ F ++TA+ D++ LYD S
Sbjct: 8 VSLELSEEIIQSMEPGAVFRDYNCR---ISSIDFHKTSTCMVTASDDDSIRLYDVASATC 64
Query: 61 LNTIASKKYGCHSAKFTHAQSECIYSSTMKSFD-IRHLNLETNTYLRYFQGHGALVSDIQ 119
L TI SKKYG FT + IYSS D +R L+L N YLRYF+GH V +
Sbjct: 65 LKTINSKKYGVDLVCFTSHPTTVIYSSRNGWDDSLRLLSLHDNKYLRYFKGHHDRVVSLS 124
Query: 120 MSPLDDTFLSASYDESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGL 179
+ + F+S S D +V LWD R K Q L+ AYD GL+FAI + +
Sbjct: 125 LCSGGECFISGSLDRTVLLWDQRVEKCQGLLRVQGRPAAAYDDQGLIFAIA--FGGYIRM 182
Query: 180 YNVKHLKAGPFLVINVDPSFDQWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSG 239
++ + + GPF + +V + N ++FSNDG+ +LL + G ++DSF GT L S
Sbjct: 183 FDARMYEKGPFEIFSVGGDLSEANVVKFSNDGRLMLLTTMDGFIHVLDSFRGTLLSTFS- 241
Query: 240 TKPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWNHADFISGRTLKPQGFINAAPNTC 299
KP +D A F+P+G + G W SG+ + + +
Sbjct: 242 VKPVAGESTLD---AAFSPEGMFVVSGSGDGSTHAWG---VRSGKQVHSWMGLGSE---- 291
Query: 300 PRTIAFNPKYSMFVTADETVDFYV 323
P I + P MFVT + F +
Sbjct: 292 PPVIKWGPGSPMFVTGSSELAFVI 315
>CE04149 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 248
Score = 102 bits (255), Expect = 6e-22
Identities = 69/229 (30%), Positives = 124/229 (54%), Gaps = 9/229 (3%)
Query: 15 PVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSA 74
P K F + +L + + D G L+ + A D + +YD +I KKYG +
Sbjct: 20 PSKKFNETSNKL---LDLAYSDDGNNLIVS-AEDVVLVYDLRDGSKGKSIECKKYGVNCL 75
Query: 75 KFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLD-DTFLSASYD 133
++ +C++S + IR L+L+ +Y+RYF GH V+ I+ +P D + FLS+S D
Sbjct: 76 EYLDTV-KCVHSGPNDT-TIRLLHLQKKSYVRYFDGHRMPVNFIRTNPKDREKFLSSSVD 133
Query: 134 ESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFL-V 192
+R++D R+ + + + IA+DP G++FA+ ++ + L++++ GPF
Sbjct: 134 GEIRMFDTRTFENYGCLLAGHTPLIAFDPDGILFAVAT-KSDTIKLFDMRSFDLGPFQSF 192
Query: 193 INVDPSFDQWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTK 241
I D+W+ +EFS GK++L++++AG +D+FDGT + S K
Sbjct: 193 IITKTDNDEWSDIEFSPCGKFILISTTAGSVKWIDAFDGTLIHSFSQHK 241
>7295945 [ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA
cleavage factor II complex subunit SWD2
Length = 386
Score = 94.4 bits (233), Expect = 2e-19
Identities = 74/253 (29%), Positives = 121/253 (47%), Gaps = 15/253 (5%)
Query: 74 AKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPL-DDTFLSASY 132
A F + ++S++ + IR L+L T +R F GH ++ + P ++ F+SA
Sbjct: 61 ACFVQQDTRVLHSTSKHDYTIRCLDLNTRHCVRVFGGHAKTINRLASQPGGENVFISAGR 120
Query: 133 DESVRLWDLRSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPF-- 190
D+ V +WD+R I +L A+DP GL A + + + +V+ + P
Sbjct: 121 DDQVYMWDIRVKTHTHRIKNLRRPLCAFDPEGLFLATSS-GTEGIQIRDVRMMGGEPSRK 179
Query: 191 LVINVDPSFDQWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTKPFPLREFMD 250
V V+ + W +L+F+ +GK LLL++ + + DGT +G LR +D
Sbjct: 180 FVYQVNAKAN-WTQLQFAPNGKSLLLSTDHSWCFSVSAIDGTYQQSFTGYSN-KLRLPLD 237
Query: 251 SGSATFTPDGRITLGTDYTGKIAIWNHADFISGRTLKPQGFINAAPNTCPRTIAFNPKYS 310
AT+TPD + L G+I IW AD LK N P C R FNP+ +
Sbjct: 238 ---ATYTPDSQFILSGADKGRIHIWRAADGFPVAVLKGN---NMGPVRCMR---FNPRAT 288
Query: 311 MFVTADETVDFYV 323
MFV++D + F++
Sbjct: 289 MFVSSDSRIVFWM 301
>7290331 [R] KOG0266 WD40 repeat-containing protein
Length = 361
Score = 67.0 bits (162), Expect = 4e-11
Identities = 51/215 (23%), Positives = 99/215 (45%), Gaps = 8/215 (3%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSST 88
+++V F +G++L +++A + ++ A +F TI+ K G ++ + S
Sbjct: 75 VSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSD 134
Query: 89 MKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSKAQA 148
K+ + L+ T L+ +GH V +P + +S S+DESVR+WD+R+ K
Sbjct: 135 DKTLKVWELS--TGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLK 192
Query: 149 LIP--SLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNKLE 206
+P S + + ++ G + + + GL + +G L +D + ++
Sbjct: 193 TLPAHSDPVSAVHFNRDGSLIVSSSYD----GLCRIWDTASGQCLKTLIDDDNPPVSFVK 248
Query: 207 FSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTK 241
FS +GKY+L A+ + D G L +G K
Sbjct: 249 FSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 283
>Hs16554627 [R] KOG0266 WD40 repeat-containing protein
Length = 334
Score = 66.2 bits (160), Expect = 6e-11
Identities = 50/215 (23%), Positives = 101/215 (46%), Gaps = 8/215 (3%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSST 88
++SV F +G++L +++A + ++ A +F TI+ K G ++ + + +S
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107
Query: 89 MKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSKAQA 148
K+ I ++ + L+ +GH V +P + +S S+DESVR+WD+++ K
Sbjct: 108 DKTLKI--WDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 165
Query: 149 LIP--SLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNKLE 206
+P S + + ++ G + + + GL + +G L +D + ++
Sbjct: 166 TLPAHSDPVSAVHFNRDGSLIVSSSYD----GLCRIWDTASGQCLKTLIDDDNPPVSFVK 221
Query: 207 FSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTK 241
FS +GKY+L A+ + D G L +G K
Sbjct: 222 FSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 256
>CE06574 [R] KOG0266 WD40 repeat-containing protein
Length = 501
Score = 65.5 bits (158), Expect = 1e-10
Identities = 60/250 (24%), Positives = 104/250 (41%), Gaps = 12/250 (4%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSST 88
++ + F G+YL T +A + +++ V +L T+AS + G + F+ + + +S
Sbjct: 216 VSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGIND--FSWSSNSQFIASA 273
Query: 89 MKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSKAQA 148
++ ++ + LR +GH V +P SA +DE+VR+WD ++
Sbjct: 274 SDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGLCVK 333
Query: 149 LIP--SLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNKLE 206
IP S T I+Y+ G A + + G V +G L VD +
Sbjct: 334 CIPAHSDPITSISYNHDGNTMATSSYD----GCIRVWDAASGSCLKTLVDTDHAPVTFVC 389
Query: 207 FSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTKPFPLREFMDSGSATFTPDGRITLGT 266
FS +GKYLL A + D L +G K F + P G+ +
Sbjct: 390 FSPNGKYLLSAQLDSSLKLWDPKKAKPLKYYNGHKNKKYCLFANMS----VPLGKHIISG 445
Query: 267 DYTGKIAIWN 276
G+I +W+
Sbjct: 446 SEDGRILVWS 455
>CE00901 [R] KOG0266 WD40 repeat-containing protein
Length = 376
Score = 60.8 bits (146), Expect = 3e-09
Identities = 52/217 (23%), Positives = 99/217 (44%), Gaps = 16/217 (7%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSS- 87
I+S F G+YL T++A + +++ T+ K G + ++ + S C+ S+
Sbjct: 90 ISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWS-SDSRCVVSAS 148
Query: 88 ---TMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSS 144
T+K F+I T+ + +GH V +P +S S+DESVR+WD+++
Sbjct: 149 DDKTLKIFEI-----VTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTG 203
Query: 145 KAQALIP--SLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQW 202
+P S + ++++ G + A G+ + GL + G + VD
Sbjct: 204 MCIKTLPAHSDPVSAVSFNRDGSLIASGSYD----GLVRIWDTANGQCIKTLVDDENPPV 259
Query: 203 NKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSG 239
++FS +GKY+L ++ + D G L + +G
Sbjct: 260 AFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTG 296
>SPBC354.03 [R] KOG0266 WD40 repeat-containing protein
Length = 380
Score = 59.7 bits (143), Expect = 6e-09
Identities = 45/194 (23%), Positives = 94/194 (48%), Gaps = 12/194 (6%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSST 88
+T V+ + +++ T+++ + ++ A++ R T+ G K+ +S
Sbjct: 57 VTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYLASASD 116
Query: 89 MKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSKAQA 148
K+ IR + E +R +GH VS I +PL +S S+DE+VR+W+L+
Sbjct: 117 DKT--IRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLR 174
Query: 149 LIPS----LVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNK 204
++P+ ++ I+ D G + A + + G+ + + +G L V+P +
Sbjct: 175 MLPAHSEPIISVSISAD--GTLCATASYD----GMARIWDVLSGQCLKTLVEPINVPLSN 228
Query: 205 LEFSNDGKYLLLAS 218
L+F+ + KYLL+++
Sbjct: 229 LQFTENRKYLLVSN 242
>Hs4826956 [A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA
processing complex
Length = 919
Score = 58.2 bits (139), Expect = 2e-08
Identities = 37/145 (25%), Positives = 65/145 (44%), Gaps = 6/145 (4%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSST 88
+T VTF G ++T++ + +D R T S + S A E + +
Sbjct: 418 VTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGA 477
Query: 89 MKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDL----RSS 144
SF+I +++T L GH +S + +P+ SAS+D++VRLWD+ R+
Sbjct: 478 QDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTK 537
Query: 145 KAQALIPSLVPTCIAYDPSGLVFAI 169
+ AL + + + P G A+
Sbjct: 538 ETLALTSDAL--AVTFRPDGAELAV 560
>Hs9506645 [R] KOG0266 WD40 repeat-containing protein
Length = 330
Score = 57.4 bits (137), Expect = 3e-08
Identities = 48/218 (22%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSS- 87
++SV F +G++L +++A + ++ A ++ T+ ++ S + +S
Sbjct: 44 VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103
Query: 88 --TMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSK 145
T+K +D+R + L+ +GH V +P + +S S+DE+V++W++++ K
Sbjct: 104 DKTLKLWDVR-----SGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGK 158
Query: 146 AQALIP--SLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWN 203
+ S + + ++ SG + G+ + GL + +G L VD +
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYD----GLCRIWDAASGQCLKTLVDDDNPPVS 214
Query: 204 KLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTK 241
++FS +GKY+L A+ + D G L +G K
Sbjct: 215 FVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQK 252
Score = 50.1 bits (118), Expect = 4e-06
Identities = 49/187 (26%), Positives = 78/187 (41%), Gaps = 18/187 (9%)
Query: 104 YLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSKAQALI---PSLVPTCIAY 160
Y + GH +SD+ S +SAS D++++LWD+RS K + + V C
Sbjct: 75 YEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFN 134
Query: 161 DPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNKLEFSNDGKYLLLASSA 220
PS L+ I + V ++ VK K L + DP + + F+ G ++ S
Sbjct: 135 PPSNLI--ISGSFDETVKIWEVKTGKCLKTLSAHSDPV----SAVHFNCSGSLIVSGSYD 188
Query: 221 GKHLIMDSFDGTQLFELSGTKPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWNHADF 280
G I D+ G L L P+ F+P+G+ L + +W D+
Sbjct: 189 GLCRIWDAASGQCLKTLVDDDNPPV------SFVKFSPNGKYILTATLDNTLKLW---DY 239
Query: 281 ISGRTLK 287
GR LK
Sbjct: 240 SRGRCLK 246
Score = 49.7 bits (117), Expect = 6e-06
Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Query: 23 DKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYG--CHSAKFTHAQ 80
D + P++ V F +G+Y+LTAT + + L+D R L T +K C A F+
Sbjct: 207 DDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTG 266
Query: 81 SECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASY--DESVRL 138
+ I S + + + NL+T ++ QGH +V P ++ SA+ D++++L
Sbjct: 267 GKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKL 325
Query: 139 W 139
W
Sbjct: 326 W 326
>7302720 [R] KOG0266 WD40 repeat-containing protein
Length = 307
Score = 57.4 bits (137), Expect = 3e-08
Identities = 56/254 (22%), Positives = 109/254 (42%), Gaps = 17/254 (6%)
Query: 27 GPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQ--SECI 84
G +T + F +G+ L++++ + L+D + R + ++A G + ++ A + C
Sbjct: 57 GCVTGLKFSSNGENLVSSSGDRLLKLWDLSATRCIQSLAGHGDGVNDVAWSAAGLIASCS 116
Query: 85 YSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSS 144
T++ +D R + ++ +GH +P + S S+DE+VRLWD+R+
Sbjct: 117 DDMTVRLWDAR-----SKLCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVRTG 171
Query: 145 KAQALIPSLVP--TCIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQW 202
K ++ + T + + G +F + + GL + G L VD
Sbjct: 172 KTLKIVHAHQDPITSVDFHRDGNIFVTSSYD----GLVRLWDSSTGHVLKTLVDVDNIPV 227
Query: 203 NKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTKPFPLREFMDSGSATFTPDGRI 262
++FS +G+Y +L+S+ L + ++ + T L EF S S T G
Sbjct: 228 GYVKFSPNGRY-ILSSTLNNTLRLWNYKKPKCMR---TYRGHLNEFYCSNSNFSTTGGIW 283
Query: 263 TLGTDYTGKIAIWN 276
+ + IWN
Sbjct: 284 IVSGSEDNTLCIWN 297
>SPBC713.04c [A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA
processing complex
Length = 854
Score = 55.1 bits (131), Expect = 1e-07
Identities = 47/172 (27%), Positives = 75/172 (43%), Gaps = 14/172 (8%)
Query: 108 FQGHGALVSDIQMSPLDDTFLSASYDESVRLWDL---RSSKAQALIPSLVPTCIAYDPSG 164
F H + VS + S + S+S D SVR WDL R+ + + +CIA DPSG
Sbjct: 377 FTQHTSAVSGLCFSKRGNVLFSSSLDGSVRAWDLIRYRNFRTFTAPSRVQFSCIAVDPSG 436
Query: 165 LVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNKLEFSNDGKYLLLASSAGKHL 224
+ G+ ++ E+ +++V+ + L + P + L F++ G L S
Sbjct: 437 EIVCAGSQDSFEIFMWSVQTGQLLETLAGHEGPV----SSLSFNSSGSLLASGSWDKTVR 492
Query: 225 IMDSFDGTQLFELSGTKPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWN 276
I D F + + E P P+ D S F PDG+ G++ WN
Sbjct: 493 IWDIFSRSGIVE-----PLPIPS--DVLSLAFHPDGKEVCVASLDGQLTFWN 537
Score = 49.3 bits (116), Expect = 8e-06
Identities = 37/161 (22%), Positives = 72/161 (43%), Gaps = 5/161 (3%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSST 88
++ + F G L +++ ++ +D + R T + S E + + +
Sbjct: 384 VSGLCFSKRGNVLFSSSLDGSVRAWDLIRYRNFRTFTAPSRVQFSCIAVDPSGEIVCAGS 443
Query: 89 MKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDL--RSSKA 146
SF+I +++T L GH VS + + S S+D++VR+WD+ RS
Sbjct: 444 QDSFEIFMWSVQTGQLLETLAGHEGPVSSLSFNSSGSLLASGSWDKTVRIWDIFSRSGIV 503
Query: 147 QAL-IPSLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLK 186
+ L IPS V +A+ P G + + + ++ +NV+ K
Sbjct: 504 EPLPIPSDV-LSLAFHPDGKEVCVASLDG-QLTFWNVQEGK 542
>7303694 [A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA
processing complex
Length = 949
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/272 (19%), Positives = 108/272 (38%), Gaps = 29/272 (10%)
Query: 6 SKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIA 65
SK L + F + +T + F + ++L++++ + +D R T
Sbjct: 415 SKVKLWNTQSSFCFVTFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRAFDVNRYRNFRTFT 474
Query: 66 SKKYGCHSAKFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPL-- 123
S S E + + FDI +++T L GH V I SP+
Sbjct: 475 SPNPAQFSCVAVDYSGELVVAGGQDVFDIFLWSVKTGKLLEIISGHEGPVVSIAFSPVAT 534
Query: 124 DDTFLSASYDESVRLWDLRSSKAQALIPSLVP--TCIAYDPSGLVFAIGNPENHEVGLYN 181
T +S S+D++V++W+ S ++ V T + + PSG A+ + + +++
Sbjct: 535 SSTLVSGSWDKTVKIWNCLESNSEHETIDAVSDVTNVTFSPSGEEIAVATLSGN-ITIFD 593
Query: 182 VK------------HLKAG----PFLVINVDPSFDQWNKLEFSNDGKYLLLASSAG---- 221
+K L AG + + + ++ +E+S DG+ +L A +
Sbjct: 594 IKSAGQVTTIEGRNDLSAGRLETDIITARKNAQANYFSTIEYSADGECILAAGKSANICI 653
Query: 222 ----KHLIMDSFDGTQLFELSGTKPFPLREFM 249
+ +++ F+ TQ L G F R+ +
Sbjct: 654 YHVREAILLKKFEITQNHSLDGLNDFISRKHL 685
>At4g02730 [R] KOG0266 WD40 repeat-containing protein
Length = 333
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/218 (19%), Positives = 94/218 (42%), Gaps = 13/218 (5%)
Query: 6 SKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIA 65
+ N+ ++P + + + I+ V F + G L +A+ M L+ A + ++
Sbjct: 23 TSGNVPIYKPYRHLKTLEGHTAAISCVKFSNDGNLLASASVDKTMILWSATNYSLIHRYE 82
Query: 66 SKKYGCHSAKFT---HAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSP 122
G ++ H T++ +D R L+ +GH V + +P
Sbjct: 83 GHSSGISDLAWSSDSHYTCSASDDCTLRIWDAR----SPYECLKVLRGHTNFVFCVNFNP 138
Query: 123 LDDTFLSASYDESVRLWDLRSSKAQALIP--SLVPTCIAYDPSGLVFAIGNPENHEVGLY 180
+ +S S+DE++R+W++++ K +I S+ + + ++ G + + + G
Sbjct: 139 PSNLIVSGSFDETIRIWEVKTGKCVRMIKAHSMPISSVHFNRDGSLIVSASHD----GSC 194
Query: 181 NVKHLKAGPFLVINVDPSFDQWNKLEFSNDGKYLLLAS 218
+ K G L +D + +FS +GK++L+A+
Sbjct: 195 KIWDAKEGTCLKTLIDDKSPAVSFAKFSPNGKFILVAT 232
>Hs7657439 [K] KOG0263 Transcription initiation factor TFIID subunit TAF5
(also component of histone acetyltransferase SAGA)
Length = 589
Score = 53.1 bits (126), Expect = 5e-07
Identities = 48/192 (25%), Positives = 78/192 (40%), Gaps = 14/192 (7%)
Query: 87 STMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDL-RSSK 145
S + IR+ +L + T +QGH V D+ +SP F S S+D + RLW R+
Sbjct: 359 SCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYP 418
Query: 146 AQALIPSLVPT-CIAYDPSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNK 204
+ L C+ + P+ A G+ + V L++ + + + P
Sbjct: 419 LRIYAGHLADVDCVKFHPNSNYLATGSTDK-TVRLWSAQQGNSVRLFTGHRGPVL----S 473
Query: 205 LEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTKPFPLREFMDSGSATFTPDGRITL 264
L FS +GKYL A + + D GT EL G + S TF+PD +
Sbjct: 474 LAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD-------NITSLTFSPDSGLIA 526
Query: 265 GTDYTGKIAIWN 276
+ +W+
Sbjct: 527 SASMDNSVRVWD 538
>YCR057c [A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA
processing complex
Length = 923
Score = 52.8 bits (125), Expect = 7e-07
Identities = 32/166 (19%), Positives = 74/166 (44%), Gaps = 3/166 (1%)
Query: 23 DKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSE 82
++ +T+V F GQ + +++ + +D + R T + + E
Sbjct: 384 EEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGE 443
Query: 83 CIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDL- 141
+ + ++ +FDI +++T L GH VS + S + SAS+D+++R+W +
Sbjct: 444 VVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIF 503
Query: 142 -RSSKAQALIPSLVPTCIAYDPSGLVFAIGNPENHEVGLYNVKHLK 186
RS + + + ++ P G A+ + ++ ++N++ K
Sbjct: 504 GRSQQVEPIEVYSDVLALSMRPDGKEVAVSTLKG-QISIFNIEDAK 548
Score = 51.2 bits (121), Expect = 2e-06
Identities = 46/178 (25%), Positives = 79/178 (43%), Gaps = 14/178 (7%)
Query: 105 LRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDL---RSSKAQALIPSLVPTCIAYD 161
L F+ H + V+ +Q + S+S D +VR WDL R+ + + C+A D
Sbjct: 380 LATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVD 439
Query: 162 PSGLVFAIGNPENHEVGLYNVKHLKAGPFLVINVDPSFDQWNKLEFSNDGKYLLLASSAG 221
PSG V G+ +N ++ +++V+ + L + P + L FS + L AS
Sbjct: 440 PSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPV----SCLSFSQENSVLASASWDK 495
Query: 222 KHLIMDSFDGTQLFELSGTKPFPLREFMDSGSATFTPDGRITLGTDYTGKIAIWNHAD 279
I F +Q E P+ + D + + PDG+ + G+I+I+N D
Sbjct: 496 TIRIWSIFGRSQQVE-------PIEVYSDVLALSMRPDGKEVAVSTLKGQISIFNIED 546
>Hs13376840 [R] KOG4155 FOG: WD40 repeat
Length = 305
Score = 52.4 bits (124), Expect = 9e-07
Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 8/140 (5%)
Query: 5 ISKSNLLRFEPVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTI 64
+ K N+ E K D I S+ + G+YL + ++++D + + L+T+
Sbjct: 127 VGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTL 186
Query: 65 ASKKYGCHSAKFTHAQSECIYSST---MKSFDIRHLNLETNTYLRYFQGHGALVSDIQMS 121
S F+ + +S +K +D++H NL GH + V ++
Sbjct: 187 EGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGT-----LSGHASWVLNVAFC 241
Query: 122 PLDDTFLSASYDESVRLWDL 141
P D F+S+S D+SV++WD+
Sbjct: 242 PDDTHFVSSSSDKSVKVWDV 261
>At3g49660 [R] KOG0266 WD40 repeat-containing protein
Length = 317
Score = 51.2 bits (121), Expect = 2e-06
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Query: 23 DKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIAS--KKYGCHSAKFTHAQ 80
D E P++ V F +G+++L T + + L++ S +FL T C S+ F+
Sbjct: 195 DDENPPVSFVRFSPNGKFILVGTLDNTLRLWNISSAKFLKTYTGHVNAQYCISSAFSVTN 254
Query: 81 SECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLW 139
+ I S + + + L + L+ +GH V ++ P ++ S S D++VR+W
Sbjct: 255 GKRIVSGSEDNC-VHMWELNSKKLLQKLEGHTETVMNVACHPTENLIASGSLDKTVRIW 312
>Hs19705568 [R] KOG0288 WD40 repeat protein TipD
Length = 293
Score = 50.4 bits (119), Expect = 3e-06
Identities = 61/261 (23%), Positives = 97/261 (36%), Gaps = 35/261 (13%)
Query: 29 ITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSS- 87
ITS+ FD G YLL A+ ++ R +T+ SAKF + + S
Sbjct: 28 ITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSH 87
Query: 88 --TMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSK 145
T+K +D+R + G+ +DI + + +S +D+ +R WD+RS
Sbjct: 88 DRTLKLWDLRSKVCIKTVFA------GSSCNDIVCT--EQCVMSGHFDKKIRFWDIRSES 139
Query: 146 AQALIPSLVPTCIAYDPSGLVFAIG-NPENHEV------GLYNVKHLKAGPFLVINVDPS 198
+ L G + A+ NPE E+ L V L+ P
Sbjct: 140 IVREMELL----------GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPG 189
Query: 199 F---DQWNKLEFSNDGKYLLLASSAGKHLIMDSFDGTQLFELSGTKPFPLREFMDSGSA- 254
F W ++ FS DG Y+ S+ G I G LS + P + A
Sbjct: 190 FKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSNSTAHPSMRWRGRPLAR 249
Query: 255 ---TFTPDGRITLGTDYTGKI 272
+T D ++ G G +
Sbjct: 250 TLSVWTKDAKLCCGHSTDGAL 270
>Hs14150114 [S] KOG0316 Conserved WD40 repeat-containing protein
Length = 315
Score = 49.7 bits (117), Expect = 6e-06
Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 2/133 (1%)
Query: 15 PVKSFRVSDKELGPITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSA 74
P K + D G + +V F+ G Y LT + + L++ + L T + Y A
Sbjct: 14 PQKRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDA 73
Query: 75 KFTHAQSECIYSSTMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDE 134
+ S K+ + ++ + +R F+GH V+ +Q + LS S D
Sbjct: 74 AGSFDNSSLCSGGGDKAVVL--WDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDS 131
Query: 135 SVRLWDLRSSKAQ 147
S+R WD RS + +
Sbjct: 132 SIRCWDCRSRRPE 144
>7296695 [A] KOG0284 Polyadenylation factor I complex subunit PFS2
Length = 439
Score = 48.9 bits (115), Expect = 1e-05
Identities = 64/315 (20%), Positives = 126/315 (39%), Gaps = 45/315 (14%)
Query: 28 PITSVTFDDHGQYLLTATASDNMHLYDAVSCRFLNTIASKKYGCHSAKFTHAQSECIYSS 87
PI ++ + G+ L+T +S L++ ++ F + + + ++H S +
Sbjct: 148 PIFTLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDISVRTMVWSHNDSWMVTGD 207
Query: 88 TMKSFDIRHLNLETNTYLRYFQGHGALVSDIQMSPLDDTFLSASYDESVRLWDLRSSKAQ 147
N+ ++ +Q H + I SP D F+S S D ++R+WD + +
Sbjct: 208 HGGYVKYWQSNMNN---VKMYQAHKEAIRGISFSPTDSKFVSGSDDGTLRIWDFMRCQEE 264
Query: 148 ALI--PSLVPTCIAYDPSGLVFAIGNPENHE-VGLYNVKHLKAGPFLVINVDPSFDQWNK 204
++ C+ + P + G+ +N + + +++ K A L + D
Sbjct: 265 RVLRGHGADVKCVHWHPQKGMIVSGSKDNQQPIKIWDPKSGIALATLHAHKSTVMD---- 320
Query: 205 LEFSNDGKYLLLASSAGKHL-----IMDSFDGTQLF-----ELSGTKPFPLRE--FMDSG 252
L+++++G +L+ AS HL I + + Q+F E S P+ E F G
Sbjct: 321 LKWNDNGNWLVTASR--DHLLKLFDIRNLREEVQVFRGHKKEASSVSWHPIHEGLFCSGG 378
Query: 253 SATFTPDGRITLGTDYTGKIAIWNHADFISGRTLKPQGFINAAPNTCPRTIAFNPKYSMF 312
S G I WN + T K G + A ++ T+A++P +
Sbjct: 379 S---------------DGSILFWN----VGRSTDKEIGCVETAHDSIVWTLAWHPLGHIL 419
Query: 313 VTA--DETVDFYVYN 325
+ D T+ F+ N
Sbjct: 420 CSGSNDHTIKFWTRN 434
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,023,015
Number of Sequences: 60738
Number of extensions: 875653
Number of successful extensions: 3798
Number of sequences better than 1.0e-05: 28
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3648
Number of HSP's gapped (non-prelim): 82
length of query: 326
length of database: 30,389,216
effective HSP length: 107
effective length of query: 219
effective length of database: 23,890,250
effective search space: 5231964750
effective search space used: 5231964750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)