ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4768 suspect: Pn R KOG1721 General function prediction only FOG: Zn-finger
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4768 1638169 1637573 -199
(199 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
Hs18579598 [R] KOG1721 FOG: Zn-finger 30 1.7
Hs14758036 [R] KOG1721 FOG: Zn-finger 30 1.7
Hs4508027 [R] KOG1721 FOG: Zn-finger 30 2.2
Hs20535384 [R] KOG1721 FOG: Zn-finger 30 2.2
Hs22052554 [R] KOG1721 FOG: Zn-finger 30 2.8
Hs20534295 [R] KOG1721 FOG: Zn-finger 30 2.8
YIL079c [O] KOG4400 E3 ubiquitin ligase interacting with arginin... 29 3.7
Hs7706781 [R] KOG1721 FOG: Zn-finger 29 4.8
Hs4507985 [R] KOG1721 FOG: Zn-finger 29 4.8
Hs17435019 [R] KOG1721 FOG: Zn-finger 29 4.8
Hs16418391 [R] KOG1721 FOG: Zn-finger 29 4.8
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 28 6.3
Hs8922675 [O] KOG0802 E3 ubiquitin ligase 28 6.3
Hs20472542 [R] KOG1721 FOG: Zn-finger 28 6.3
SPAC17G6.05c [R] KOG2220 Predicted signal transduction protein 28 8.2
CE08447 [R] KOG1246 DNA-binding protein jumonji/RBP2/SMCY contai... 28 8.2
>Hs18579598 [R] KOG1721 FOG: Zn-finger
Length = 261
Score = 30.4 bits (67), Expect = 1.7
Identities = 38/170 (22%), Positives = 61/170 (35%), Gaps = 37/170 (21%)
Query: 5 GVTIQDTTK--RLRKIVRVKTPGNCISCGRTF---EVIWYRLPWSKLDKNRICDSCHARY 59
G TTK R +KI V+ P C CG+ F + + +K +C C +
Sbjct: 65 GKDFSTTTKLNRHKKIHTVEKPYKCYECGKAFNWSSHLQIHMRVHTGEKPYVCSECGRGF 124
Query: 60 TRTATRFLDNKYNYIPSKSELHKTEVLPLVKGSLPDGLEVESFPCVKCKNVTYRDPNVKP 119
+ ++ + + +H E + F C +C ++
Sbjct: 125 SNSSNLCMHQR---------VHTGE---------------KPFKCEECGKAFRHTSSLCM 160
Query: 120 WQRLEA--KPGQKCYGCHNGFKSSPALVPWDKMN----PERICAGCAFRF 163
QR+ KP KCY C F S +L +++ P R C GC F
Sbjct: 161 HQRVHTGEKP-YKCYECGKAFSQSSSLCIHQRVHTGEKPYR-CCGCGKAF 208
>Hs14758036 [R] KOG1721 FOG: Zn-finger
Length = 548
Score = 30.4 bits (67), Expect = 1.7
Identities = 29/138 (21%), Positives = 55/138 (39%), Gaps = 9/138 (6%)
Query: 4 EGVTIQDTTKRLRKIVRVKTPGNCISCGRTFEVIWYRLPWSKL---DKNRICDSCHARYT 60
E + + +R R+I + P C CG+TF Y +L +K C+ C +
Sbjct: 220 EAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTFG 279
Query: 61 RTATRFLDNKYNYIPSKSELHKTEVLPLVKGSLPDGLEVES----FPCVKCKNVTYRDPN 116
R + + + + ++ K SL L + + + C +C V R +
Sbjct: 280 RNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSS 339
Query: 117 VKPWQRLEAKPGQKCYGC 134
++ +R+ G+K Y C
Sbjct: 340 LEKHRRIHT--GEKPYKC 355
>Hs4508027 [R] KOG1721 FOG: Zn-finger
Length = 803
Score = 30.0 bits (66), Expect = 2.2
Identities = 36/143 (25%), Positives = 56/143 (38%), Gaps = 20/143 (13%)
Query: 16 RKIVRVKTPGNCISCGRTFEVIW-YRLPWSKL----DKNRICDSCHARYTRTATRFLDNK 70
+KI K P C CG+ F+ W +L KL +K C+ C + +T K
Sbjct: 383 KKIHTEKKPYKCEECGKAFK--WSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTL---TK 437
Query: 71 YNYIPSKSELHKTEVLPLVKGSLPD-------GLEVESFPCVKCKNVTYRDPNVKPWQR- 122
+N I + + +K EV + + + C +C R N+ ++
Sbjct: 438 HNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKI 497
Query: 123 -LEAKPGQKCYGCHNGFKSSPAL 144
+E KP KC C FK S L
Sbjct: 498 HIEKKP-YKCEECGKAFKWSSKL 519
>Hs20535384 [R] KOG1721 FOG: Zn-finger
Length = 436
Score = 30.0 bits (66), Expect = 2.2
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 100 ESFPCVKCKNVTYRDPNVKPWQRLEA--KPGQKCYGCHNGFKSSPAL 144
+S+ C +C N YR ++ +R+ + KP KC C F+ S AL
Sbjct: 276 KSYKCEECGNAFYRSSHLTKHKRIHSGQKP-YKCEECGKAFRQSSAL 321
>Hs22052554 [R] KOG1721 FOG: Zn-finger
Length = 795
Score = 29.6 bits (65), Expect = 2.8
Identities = 36/167 (21%), Positives = 63/167 (37%), Gaps = 34/167 (20%)
Query: 27 CISCGRTFEVIWYRLPWSKL---DKNRICDSCHARYTRTATRFLDNKYNYIPSKSELHKT 83
C+ CGRTF I + ++ K C+ C + N+Y+ ++H
Sbjct: 627 CLECGRTFTRIVTLIEHQRIHTGQKPYQCNECEKAF---------NQYSSFNEHRKIHTG 677
Query: 84 EVLPLVKGSLPDGLEVESFPCVKCKNVTYRDPNVKPWQRLEA--KPGQKCYGCHNGFKSS 141
E L + C +C N+ QR+ KP Q C C F
Sbjct: 678 EKL---------------YTCEECGKAFGCKSNLYRHQRIHTGEKPYQ-CNQCGKAFSQY 721
Query: 142 PALVPWDKMNP-ERI--CAGCAFRFHTYRARGFRARQNSTKSRQQLW 185
L ++++ E++ C C + ++YR+ R ++ TK + W
Sbjct: 722 SFLTEHERIHTGEKLYKCMECG-KAYSYRSNLCRHKKVHTKEKLYKW 767
>Hs20534295 [R] KOG1721 FOG: Zn-finger
Length = 876
Score = 29.6 bits (65), Expect = 2.8
Identities = 35/143 (24%), Positives = 59/143 (40%), Gaps = 32/143 (22%)
Query: 6 VTIQDTTKRLRKIVRVKTPGNCISCGRTFEVIWYRLPWSKLDKNRICDSCHARYTRTATR 65
V IQ++ K++ + C C +TF+ I +K CD CH RY+ +
Sbjct: 351 VVIQNSNKKILQ---------CPKCDKTFDRIG--------EKPFECDICHQRYSTKSNL 393
Query: 66 FLDNKYNYIPSKSELHKTE-------VLPLVKGSLPDGLEVESFPCVKCKNVTYRDPNVK 118
+ K + +++E HK E L K +L ++ + CK R P+++
Sbjct: 394 TVHRKKH--SNETEFHKKEHKCPYCNKLHASKKTLAKHVKRQI-----CKKSFTRRPHLE 446
Query: 119 PWQRLEAKPGQ-KCYGCHNGFKS 140
L ++ KC C FKS
Sbjct: 447 EHMILHSQDKPFKCTYCEEHFKS 469
>YIL079c [O] KOG4400 E3 ubiquitin ligase interacting with arginine
methyltransferase
Length = 360
Score = 29.3 bits (64), Expect = 3.7
Identities = 25/90 (27%), Positives = 37/90 (40%), Gaps = 8/90 (8%)
Query: 78 SELHKTEVLPLVKGSLPDGLEVESFPCVKCKNVTYRDPNVKPWQRLEAKPGQKCYGCHNG 137
SE+ + LP VK + P G + SF + ++ D N + L GQ Y
Sbjct: 6 SEVESIDTLPYVKDTTPTGSDSSSFNKLLAPSIEDVDANP---EELRTLRGQGRYFGITD 62
Query: 138 FKSSPALVPWDKMNPERICAGCAFRFHTYR 167
+ S+ A+ M E C C+ R H R
Sbjct: 63 YDSNGAI-----MEAEPKCNNCSQRGHLKR 87
>Hs7706781 [R] KOG1721 FOG: Zn-finger
Length = 803
Score = 28.9 bits (63), Expect = 4.8
Identities = 30/133 (22%), Positives = 48/133 (35%), Gaps = 30/133 (22%)
Query: 17 KIVRVKTPGNCISCGRTFEVIWYRLPWSKL---DKNRICDSCHARYTRTATRFLDNKYNY 73
K+ + P NC CGR F + +L +K CD+C ++R ++
Sbjct: 355 KVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRN---------SH 405
Query: 74 IPSKSELHKTEVLPLVKGSLPDGLEVESFPCVKCKNVTYRDPNVKPWQRLEA--KPGQKC 131
+ S +H E + + C +C N+ QR+ KP KC
Sbjct: 406 LQSHQRVHTGE---------------KPYKCEECGKGFICSSNLYIHQRVHTGEKP-YKC 449
Query: 132 YGCHNGFKSSPAL 144
C GF +L
Sbjct: 450 EECGKGFSRPSSL 462
>Hs4507985 [R] KOG1721 FOG: Zn-finger
Length = 469
Score = 28.9 bits (63), Expect = 4.8
Identities = 33/150 (22%), Positives = 55/150 (36%), Gaps = 28/150 (18%)
Query: 15 LRKIVRVKT---PGNCISCGRTFEVIWYRLPWSKL---DKNRICDSCHARYTRTATRFLD 68
L K R+ T P C CGRTF I + + +K C C ++ ++ F
Sbjct: 68 LTKHQRIHTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSS-FSQ 126
Query: 69 NKYNYIPSK------------SELHKTEVLPLVKGSLPDGLEVESFPCVKCKNVTYRDPN 116
++ + K +H T+ L + G P + C +C +
Sbjct: 127 HERTHTGEKPYECSECGKAFRQSIHLTQHLRIHTGEKP-------YQCGECGKAFSHSSS 179
Query: 117 VKPWQRLEAKPGQKCYGCHNGFKSSPALVP 146
+ QR+ G+K Y CH K+ + P
Sbjct: 180 LTKHQRIHT--GEKPYECHECGKAFTQITP 207
>Hs17435019 [R] KOG1721 FOG: Zn-finger
Length = 194
Score = 28.9 bits (63), Expect = 4.8
Identities = 36/141 (25%), Positives = 55/141 (38%), Gaps = 17/141 (12%)
Query: 19 VRVKT---PGNCISCGRTFEVIWYRLPWSKLDKNRI---CDSCHARYTRTATRFLDNKYN 72
VR+ T P C CG+ F+ Y K+D C+ C + R +T ++K
Sbjct: 3 VRIHTGEKPYKCKECGKAFKQSAYLNQHKKIDAGEQPYKCEECGKAF-RWSTTLSEHKKI 61
Query: 73 YIPSKSELHKTEVLPLVKGSLPDGLEVE------SFPCVKCKNVTYRDPNVKPWQRLEA- 125
++ +S K E K S P + ++ C + V N +R+
Sbjct: 62 HMGDESYKCK-ECGKAYKRSSPINKHEKIHNGENTYKCKESGKVITSSSNSAKRKRIHTG 120
Query: 126 -KPGQKCYGCHNGFKSSPALV 145
KP KC CH F SS L+
Sbjct: 121 EKP-YKCLECHKTFNSSKTLI 140
>Hs16418391 [R] KOG1721 FOG: Zn-finger
Length = 472
Score = 28.9 bits (63), Expect = 4.8
Identities = 29/138 (21%), Positives = 49/138 (35%), Gaps = 40/138 (28%)
Query: 24 PGNCISCGRTFEVIWYRLPWSKLDKNR---------ICDSCHARYTRTATRFLDNKYNYI 74
P C SCGR F W KLDK++ C++C Y + + F K
Sbjct: 194 PFECHSCGRAFGEKW------KLDKHQKTHAEERPYKCENCGNAYKQKSNLFQHQK---- 243
Query: 75 PSKSELHKTEVLPLVKGSLPDGLEVESFPCVKC-KNVTYRDPNVKPWQRLEAKPGQKCYG 133
+H E + + C C K +++ + + AK +C
Sbjct: 244 -----MHTKE---------------KPYQCKTCGKAFSWKSSCINHEKIHNAKKSYQCNE 283
Query: 134 CHNGFKSSPALVPWDKMN 151
C F+ + L+ K++
Sbjct: 284 CEKSFRQNSTLIQHKKVH 301
>YCR008w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 603
Score = 28.5 bits (62), Expect = 6.3
Identities = 14/45 (31%), Positives = 23/45 (51%), Gaps = 6/45 (13%)
Query: 99 VESFPCVKCKNVTYRDPNVKPWQRLEAKP------GQKCYGCHNG 137
+ES +C+NV Y + P++R+ K G++ CHNG
Sbjct: 555 IESLKRARCRNVIYSMLDPVPYRRINGKQILNSEWGREIKCCHNG 599
>Hs8922675 [O] KOG0802 E3 ubiquitin ligase
Length = 623
Score = 28.5 bits (62), Expect = 6.3
Identities = 16/63 (25%), Positives = 31/63 (48%), Gaps = 7/63 (11%)
Query: 94 PDGLEVESFPCVKCKNVTYRDPNVKPWQRLEAKPGQKCYGCHNGFKSSPALVPWDKMNPE 153
PD +E E+ C+ C+++ + +++P C C++G+ +L P + E
Sbjct: 254 PDKME-ETLTCIICQDLLHDCVSLQPCMHTF------CAACYSGWMERSSLCPTCRCPVE 306
Query: 154 RIC 156
RIC
Sbjct: 307 RIC 309
>Hs20472542 [R] KOG1721 FOG: Zn-finger
Length = 402
Score = 28.5 bits (62), Expect = 6.3
Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 30/133 (22%)
Query: 24 PGNCISCGRTFEVIWYRLPWSKL---DKNRICDSCHARYTRTATRFLDNKYNYIPSKSEL 80
P CI CG+TF L ++ K C+ C + + A + +
Sbjct: 174 PHKCIECGKTFRKNSILLSHQRIHTGQKPYKCNDCGKAFAQNAA---------LTRHERI 224
Query: 81 HKTEVLPLVKGSLPDGLEVESFPCVKCKNVTYRDPNVKPWQRLEA--KPGQKCYGCHNGF 138
H E + F C KC + V Q++ KP Q C C F
Sbjct: 225 HSGE---------------KPFKCNKCGRAFRDNSTVLEHQKIHTGEKPYQ-CNECGKAF 268
Query: 139 KSSPALVPWDKMN 151
+ S L+ +M+
Sbjct: 269 RKSSTLISHQRMH 281
>SPAC17G6.05c [R] KOG2220 Predicted signal transduction protein
Length = 775
Score = 28.1 bits (61), Expect = 8.2
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 115 PNVKPWQRLEAKPGQKCYGCHNGFKSSPALVPWDKMN---PERICAGCAFRFHTYRARGF 171
P + P Q L P +K YG +GF+++ +V D P + + + A+ F
Sbjct: 342 PKISPLQALPPLPLEKLYGSQDGFETAKKIVGDDLFKAFVPSAVTTASSL-YSEETAKVF 400
Query: 172 RARQ 175
RA Q
Sbjct: 401 RAEQ 404
>CE08447 [R] KOG1246 DNA-binding protein jumonji/RBP2/SMCY contains JmjC
domain
Length = 732
Score = 28.1 bits (61), Expect = 8.2
Identities = 33/140 (23%), Positives = 55/140 (38%), Gaps = 14/140 (10%)
Query: 29 SCGRTFEVIWYRLPWSKLDKNRICDSCHARYTRTATRFLDNKYNYIPSKSELHK------ 82
S G T V W + S D+ + H T + D+ IP E+ K
Sbjct: 594 SIGFTGNVSW-NIAESTFDQFAMAALVHDHNTEQS---YDSVLPIIPMAWEMAKKRAFLG 649
Query: 83 TEVLPLVKGSLPDGLEVESFPCVKCKNVTYRDPNVKPWQRLEAKPGQKCYG--CHNGFKS 140
TE+ PL+K L L +F K K+ + N++ +E ++C G C
Sbjct: 650 TEMYPLIKSILARSLAKSTFELDKAKSAGAKISNIED-ASVELSHVERCQGKKCKRDVLF 708
Query: 141 SPALVPWDKMN-PERICAGC 159
+ ++ + N E++C C
Sbjct: 709 NTVVIKQNSRNKTEKLCVDC 728
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.137 0.453
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,075,837
Number of Sequences: 60738
Number of extensions: 573236
Number of successful extensions: 1437
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1430
Number of HSP's gapped (non-prelim): 21
length of query: 199
length of database: 30,389,216
effective HSP length: 101
effective length of query: 98
effective length of database: 24,254,678
effective search space: 2376958444
effective search space used: 2376958444
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)