ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4875 good U KOG2740 Intracellular trafficking, secretion, and vesicular transport Clathrin-associated protein medium chain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4875 1669103 1670593 497
(497 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR288c [U] KOG2740 Clathrin-associated protein medium chain 196 5e-50
Hs5803000 [U] KOG2740 Clathrin-associated protein medium chain 92 2e-18
Hs6912240 [U] KOG2740 Clathrin-associated protein medium chain 87 4e-17
7290785 [U] KOG2740 Clathrin-associated protein medium chain 77 6e-14
SPBC651.11c [U] KOG2740 Clathrin-associated protein medium chain 74 7e-13
CE04654 [U] KOG2740 Clathrin-associated protein medium chain 73 9e-13
YHL019c [U] KOG0937 Adaptor complexes medium subunit family 69 1e-11
Hs9506797 [U] KOG0937 Adaptor complexes medium subunit family 65 3e-10
Hs14917109 [U] KOG0938 Adaptor complexes medium subunit family 64 4e-10
7299202 [U] KOG0937 Adaptor complexes medium subunit family 61 4e-09
Hs14210504 [U] KOG0937 Adaptor complexes medium subunit family 60 6e-09
At1g56590 [U] KOG2740 Clathrin-associated protein medium chain 60 1e-08
CE28642 [U] KOG0938 Adaptor complexes medium subunit family 59 2e-08
At1g60780 [U] KOG0937 Adaptor complexes medium subunit family 59 2e-08
CE28050 [U] KOG0937 Adaptor complexes medium subunit family 58 3e-08
At5g46630 [U] KOG0938 Adaptor complexes medium subunit family 58 4e-08
At1g10730 [U] KOG0937 Adaptor complexes medium subunit family 57 5e-08
SPBP16F5.07 [U] KOG0937 Adaptor complexes medium subunit family 57 6e-08
YPL259c [U] KOG0937 Adaptor complexes medium subunit family 55 2e-07
CE11129 [U] KOG0937 Adaptor complexes medium subunit family 55 2e-07
SPAC31A2.09c [U] KOG0938 Adaptor complexes medium subunit family 55 2e-07
YOL062c [U] KOG0938 Adaptor complexes medium subunit family 54 5e-07
>YBR288c [U] KOG2740 Clathrin-associated protein medium chain
Length = 483
Score = 196 bits (499), Expect = 5e-50
Identities = 140/531 (26%), Positives = 250/531 (46%), Gaps = 83/531 (15%)
Query: 1 MIVSIYVNDRCQETLFQYSTVAECPTFRQLVVKL-----QGKDESWESKYCNE--INSEL 53
M +S Y+ D + +FQY A P+F+ L ++ Q ++S Y + + +L
Sbjct: 1 MYLSFYITDTKNKLIFQYLLGATAPSFKHLWTRVRTTCPQLLEDSSSDDYLDHSMVGRDL 60
Query: 54 KLCRHVSLLNPVVYWCLIXXXXXXXXXX--XXXXXXXXXXXQYFDKDQLTKQKINNNLDR 111
++ ++ S++N + YWCL +YFDKD+L+ +KI NN DR
Sbjct: 61 EVYKYFSVINKLNYWCLASTSKSKGPLDCFTFLETIDRILLEYFDKDKLSIKKIVNNYDR 120
Query: 112 LSMLFHCILDAGQPVITDS---NRLKAMVPSRNDLSXXXXXXXXXXXXXXQQPDGSMFKN 168
+S++F+C ++AG+P ++D N++K VP R+DLS Q P +
Sbjct: 121 ISLIFNCCVEAGEPNVSDMLYVNKIKEAVPERSDLSKFISSTAHNLQQAVQLPQQRQQQL 180
Query: 169 GPEKXXXXXXXXXXXXXXXXXXXXXXXXXXXLVDHSVDESGVPWRMSGIN-YANNEIFID 227
+ L+++ E VPWR S + + NNE+++D
Sbjct: 181 QQNQISRGSNS--------------------LIEN---EEIVPWRTSRASKHENNELYVD 217
Query: 228 MSEEINAIVEKGK----LLTGHIKGCIDLNNHLSGQPLVEMKLGLLDHKLSHLNTTFHRC 283
+ E + + EK K LLTG I G +D+ ++L+ PLV +KL + + + + H C
Sbjct: 218 LLETFHVVFEKKKSHLRLLTGSIHGIVDVRSYLNDNPLVAVKLNTMGNDIGI--PSLHDC 275
Query: 284 ILEDKANSINDLIAGKFTKLTFVPPDGRTRLCQYTLPLVK-------RDSNLGIIDVNLQ 336
+ IND + + +TF+PPDG+ RL +Y++ L R +++G++ ++ Q
Sbjct: 276 V------EINDGVFSP-SNITFIPPDGKFRLLEYSVDLSSQVKQSGVRMNSIGLMSLHFQ 328
Query: 337 SSLGKRLDEFEVRVTVGMSTTVKEIENMSMTIRMN------RNFKGIVRVMRNTHGGVET 390
+ LGK DEFE+ + + V +++++ + ++ N ++++RNTHG E
Sbjct: 329 NGLGKDSDEFELSLNIENFKKVSQVDDLKIDLQFNVENADPNEIAYKIKILRNTHGRFEN 388
Query: 391 NMTRGEVNWHLDKNMVCGSMAVLRCIAELEPELASNDQTXXXXXXXXXXXXHLTSLLQPS 450
++ G+ W DK+ G++ VLR E E + T +
Sbjct: 389 SIIMGQGQWIFDKSTATGTVPVLRGCIEYE-----------------NTGPNFTKKVDLQ 431
Query: 451 FIKCYYEHKSQLPSGIKLQSIDVVN----GGPKKPFKGVKYLTKTGSLEYR 497
+ Y + Q SGI +++ID+V+ G K +KG KY T+TG+ + R
Sbjct: 432 TVSLEYSYIGQSASGIYVEAIDIVSGLTIGKNTKLYKGAKYKTQTGNFQVR 482
>Hs5803000 [U] KOG2740 Clathrin-associated protein medium chain
Length = 418
Score = 92.0 bits (227), Expect = 2e-18
Identities = 84/297 (28%), Positives = 139/297 (46%), Gaps = 49/297 (16%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVEK-GKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
S VPWR +G+ Y NNE + D+ EEI+AI++K G +T I+G ID L+G P ++ L
Sbjct: 163 SVVPWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMP--DLTL 220
Query: 267 GLLDHKLSHLNTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRLCQYTLPLVKRDS 326
++ +L + +FH C+ + S L+F+PPDG RL Y +
Sbjct: 221 SFMNPRLLD-DVSFHPCVRFKRWESER--------ILSFIPPDGNFRLLSYHVSA----Q 267
Query: 327 NLGIIDVNLQSSLGKR----LDEFEVRVTVGMSTTV-KEIENMSMTIRMNRNFKGIVRVM 381
NL I V ++ ++ R L FE +TVG T+ K IE +++T +M KG++ +
Sbjct: 268 NLVAIPVYVKHNISFRDSSSLGRFE--ITVGPKQTMGKTIEGVTVTSQMP---KGVLNMS 322
Query: 382 RNTHGGVET-NMTRGEVNWHLDKNMVCGSMAVLRCIAELEPELASNDQTXXXXXXXXXXX 440
G T + ++W + K + + L+ L+ + D+
Sbjct: 323 LTPSQGTHTFDPVTKMLSWDVGK-INPQKLPSLKGTMSLQAGASKPDENPT--------- 372
Query: 441 XHLTSLLQPSFIKCYYEHKSQLPSGIKLQSIDVVNGGPKKPFKGVKYLTKTGSLEYR 497
I ++ + SG+K+ +D+ G KPFKG+KY+TK G + R
Sbjct: 373 -----------INLQFKIQQLAISGLKVNRLDMY-GEKYKPFKGIKYMTKAGKFQVR 417
>Hs6912240 [U] KOG2740 Clathrin-associated protein medium chain
Length = 418
Score = 87.4 bits (215), Expect = 4e-17
Identities = 79/294 (26%), Positives = 135/294 (45%), Gaps = 43/294 (14%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVEK-GKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
S +PWR +G+ Y NNE + D+ EEI+AI++K G + I+G ID LSG P ++ L
Sbjct: 163 SNIPWRRAGVKYTNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMP--DLSL 220
Query: 267 GLLDHKLSHLNTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRLCQYTLPLVKRDS 326
++ +L + +FH CI + S L+F+PPDG RL Y +
Sbjct: 221 SFMNPRLLD-DVSFHPCIRFKRWESER--------VLSFIPPDGNFRLISYRV----SSQ 267
Query: 327 NLGIIDVNLQSSLGKRLDEFEVR--VTVGMSTTV-KEIENMSMTIRMNRNFKGIVRVMRN 383
NL I V ++ S+ + + R +T+G + K IE +++T+ M + + +
Sbjct: 268 NLVAIPVYVKHSISFKENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNM--NLTP 325
Query: 384 THGGVETNMTRGEVNWHLDKNMVCGSMAVLRCIAELEPELASNDQTXXXXXXXXXXXXHL 443
T G + + W + K + + L+ + L+ ++
Sbjct: 326 TQGSYTFDPVTKVLTWDVGK-ITPQKLPSLKGLVNLQSGAPKPEE--------------- 369
Query: 444 TSLLQPSFIKCYYEHKSQLPSGIKLQSIDVVNGGPKKPFKGVKYLTKTGSLEYR 497
PS + ++ + SG+K+ +D+ G KPFKGVKY+TK G + R
Sbjct: 370 ----NPS-LNIQFKIQQLAISGLKVNRLDMY-GEKYKPFKGVKYVTKAGKFQVR 417
>7290785 [U] KOG2740 Clathrin-associated protein medium chain
Length = 422
Score = 77.0 bits (188), Expect = 6e-14
Identities = 71/291 (24%), Positives = 130/291 (44%), Gaps = 42/291 (14%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVEK-GKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
S V WR SG+ Y NNE + D+ EE++AI++K G + I+G ID LSG P ++ L
Sbjct: 161 SAVRWRRSGVRYTNNEAYFDVIEEVDAIIDKSGSTVFAEIQGHIDCCIKLSGMP--DLTL 218
Query: 267 GLLDHKLSHLNTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRLCQYTLPLVKRDS 326
++ +L + +FH C+ + + L+F+PPDG RL Y +
Sbjct: 219 SFMNPRLFD-DVSFHPCVRYKRWEAER--------LLSFIPPDGNFRLMSYHI----SSQ 265
Query: 327 NLGIIDVNLQSSLG-KRLDEFEVRVTVGMSTTV-KEIENMSMTIRMNRNFKGIVRVMRNT 384
++ I + ++ + K ++ + +T+G T+ + ++ + + + M R ++
Sbjct: 266 SVVAIPIYIRHNFSIKTGEQGRLDLTIGPRNTLGRTVDKVKLELTMPRCVLNC--LLTPN 323
Query: 385 HGGVETNMTRGEVNWHLDKNMVCGSMAVLRCIAELEPELASNDQTXXXXXXXXXXXXHLT 444
G + ++W + + V + +R + P + D
Sbjct: 324 QGKYTFDSVTKTLSWDVGRIDV-SKLPNIRGSVSITPGTTNID----------------- 365
Query: 445 SLLQPSFIKCYYEHKSQLPSGIKLQSIDVVNGGPKKPFKGVKYLTKTGSLE 495
PS + ++ SG+K+ +D+ G KPFKGVKYLTK G +
Sbjct: 366 --ANPS-VNVQFQISQLAVSGLKVNRLDMY-GEKYKPFKGVKYLTKAGKFQ 412
>SPBC651.11c [U] KOG2740 Clathrin-associated protein medium chain
Length = 425
Score = 73.6 bits (179), Expect = 7e-13
Identities = 70/293 (23%), Positives = 127/293 (42%), Gaps = 38/293 (12%)
Query: 210 VPWRMSGINYANNEIFIDMSEEINAIVE-KGKLLTGHIKGCIDLNNHLSGQPLVEMKLGL 268
VPWR + YA NE FI + E ++A+ + GKL G +K ++ +SG PL+ + L
Sbjct: 164 VPWRTAKAKYATNEFFIHVLERVSAVYQPNGKLAFGTVKSDMECKCQISGMPLLLLSL-R 222
Query: 269 LDHKLSHLNTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRLCQYTLPLVKRDSNL 328
KL N FH+ + + D ++ F+PPDG+ L + + S
Sbjct: 223 PGTKLG--NVRFHQSVNLKRWKQHPD-------QIEFIPPDGKFTLASFQTDFATQKSLP 273
Query: 329 GIIDVNLQSSLGKRLD-EFEVRVTVGMSTTVKEIENMSMTIRMNRNFKGIVRVMRN--TH 385
+++ +LD FEVR+ +T K +EN+ + I + + K + N
Sbjct: 274 VVVEAK------NKLDGRFEVRI---RNTGKKSVENLKILITIPQALKSVTVTEGNYIFR 324
Query: 386 GGVETNMTRGEVNWHLDKNMVCGSMAVLR-CIAELEPELASNDQTXXXXXXXXXXXXHLT 444
T+M G + W + K VL +A L+ + S +++ +
Sbjct: 325 ASKYTHMEEGILEWSVKKLAWTSPALVLTGFLAPLKKDANSTEES--------------S 370
Query: 445 SLLQPSFIKCYYEHKSQLPSGIKLQSIDVVNGGPKKPFKGVKYLTKTGSLEYR 497
S + + Y+ + K++S+ ++N KK +KGVK+ ++ +R
Sbjct: 371 SYSKLEHLDLQYKLQGSTLHNFKVESLKMLNHPDKKSYKGVKHTIIAQNVSFR 423
>CE04654 [U] KOG2740 Clathrin-associated protein medium chain
Length = 332
Score = 73.2 bits (178), Expect = 9e-13
Identities = 67/287 (23%), Positives = 119/287 (41%), Gaps = 61/287 (21%)
Query: 93 QYFDKDQLTKQKINNNLDRLSMLFHCILDAGQPVITDSNRLKAMVPSRNDLSXXXXXXXX 152
QYFD + + + N + L +LD G P++T+ N L+ ++ N L
Sbjct: 92 QYFD--EFSDSSMKENCVMVFELLDEMLDNGFPLVTEMNILQDLIKPPNFLRNIANQVTG 149
Query: 153 XXXXXXQQPDGSMFKNGPEKXXXXXXXXXXXXXXXXXXXXXXXXXXXLVDHSVDESGVPW 212
P G + S +PW
Sbjct: 150 RTNLSETLPTGQL------------------------------------------SNIPW 167
Query: 213 RMSGINYANNEIFIDMSEEINAIVEK-GKLLTGHIKGCIDLNNHLSGQPLVEMKLGLLDH 271
R G+ Y NNE + D+ EEI+ IV+K G + I+G +D+ LSG P ++ + L++
Sbjct: 168 RRQGVKYTNNEAYFDVIEEIDVIVDKQGSTVFAEIQGYVDVCCKLSGMP--DLTMTLINP 225
Query: 272 KLSHLNTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRLCQYTLPLVKRDSNLGII 331
+L + +FH C+ + N+ + L+FVPPDG RL Y + N+ I
Sbjct: 226 RLLD-DVSFHPCVRYKRWE--NEKV------LSFVPPDGNFRLLSYHIAA----QNMVAI 272
Query: 332 DVNLQSSLGKRLDEFEVRVTVGMSTTV-KEIENMSMTIRMNRNFKGI 377
+ ++ + + + ++ +TVG ++ K + + M + FKG+
Sbjct: 273 PIYVRQVISLKPNAGKLDLTVGPKLSMGKVVNRLDMYGEKYKPFKGV 319
>YHL019c [U] KOG0937 Adaptor complexes medium subunit family
Length = 605
Score = 69.3 bits (168), Expect = 1e-11
Identities = 49/173 (28%), Positives = 87/173 (49%), Gaps = 21/173 (12%)
Query: 210 VPWRMSGINYANNEIFIDMSEEINAIV--EKGKLLTGHIKGCIDLNNHLSGQPLVEMKLG 267
+ WR GI+YA NE F+D+ E + ++ EKG + I G I +LSG P +++ +
Sbjct: 258 ISWRTKGIHYAKNEFFLDVIERVQYLMDFEKGVIRKNLIHGEIVCRCYLSGMPKLKISIN 317
Query: 268 LLDHKLSHL--NTTFHRCILEDKANSI-------NDLIAG-----KFTKLTFVPPDGRTR 313
+ ++ N++FH+C+ D N+I +D AG ++ F+PPDG
Sbjct: 318 KILNRDPQFMSNSSFHQCVSLDSINTIEKDEEKNSDDDAGLQAATDAREIEFIPPDGEFV 377
Query: 314 LCQYTLPLVKRDSNLGIIDVNLQS-SLGKRLDEFEVRVTVGMSTTVKEIENMS 365
LCQY L +D+ + V L+ + +L +F++++ + T K + S
Sbjct: 378 LCQYELKRHVKDAPM----VRLKDFEIKPKLKKFKIQIVTKIQTNFKPTNSTS 426
>Hs9506797 [U] KOG0937 Adaptor complexes medium subunit family
Length = 423
Score = 64.7 bits (156), Expect = 3e-10
Identities = 44/125 (35%), Positives = 60/125 (47%), Gaps = 23/125 (18%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVE-KGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR GI Y NE+FID+ E +N +V G +L I G I L LSG P E++L
Sbjct: 155 NAVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMP--ELRL 212
Query: 267 GLLDHKLSHL------------NTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRL 314
GL D L L + FH+C+ + + ND ++F+PPDG L
Sbjct: 213 GLNDRVLFELTGRSKNKSVELEDVKFHQCVRLSRFD--ND------RTISFIPPDGDFEL 264
Query: 315 CQYTL 319
Y L
Sbjct: 265 MSYRL 269
>Hs14917109 [U] KOG0938 Adaptor complexes medium subunit family
Length = 435
Score = 64.3 bits (155), Expect = 4e-10
Identities = 51/219 (23%), Positives = 99/219 (44%), Gaps = 45/219 (20%)
Query: 210 VPWRMSGINYANNEIFIDMSEEINAIVE-KGKLLTGHIKGCIDLNNHLSGQPLVEMKLGL 268
+ WR GI Y NE+F+D+ E +N ++ +G++L+ H+ G + + ++LSG P E K G+
Sbjct: 159 IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMP--ECKFGM 216
Query: 269 LD--------------------HKLSHLNTTFHRCILEDKANSINDLIAGKFTKLTFVPP 308
D ++ + TFH+C+ K +S ++F+PP
Sbjct: 217 NDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSER--------SISFIPP 268
Query: 309 DGRTRLCQY-----------TLPLVKRDSNLGI-IDVNLQSSLGKRL--DEFEVRVTVGM 354
DG L +Y +PLV+ + + V ++S+ L + EVR+ +
Sbjct: 269 DGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPL 328
Query: 355 STTVKEIENMSMTIRMNRNFKGIVRVMRNTHGGVETNMT 393
+T+ ++ M + + IV ++ G E+ ++
Sbjct: 329 NTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQIS 367
>7299202 [U] KOG0937 Adaptor complexes medium subunit family
Length = 426
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 23/125 (18%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVE-KGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR GI Y NE+F+D+ E +N + G +L I G I + +LSG P E++L
Sbjct: 157 NAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSEIVGAIKMRVYLSGMP--ELRL 214
Query: 267 GLLDHKLSHL------------NTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRL 314
GL D L + FH+C+ + ND ++F+PPDG L
Sbjct: 215 GLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFE--ND------RTISFIPPDGEFEL 266
Query: 315 CQYTL 319
Y L
Sbjct: 267 MSYRL 271
>Hs14210504 [U] KOG0937 Adaptor complexes medium subunit family
Length = 423
Score = 60.5 bits (145), Expect = 6e-09
Identities = 43/126 (34%), Positives = 60/126 (47%), Gaps = 25/126 (19%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVE-KGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR GI Y NE+F+D+ E +N +V G +L I G I + LSG P E++L
Sbjct: 155 NAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMP--ELRL 212
Query: 267 GLLDHKLSHLNT-------------TFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTR 313
GL D K+ NT FH+C+ + ND ++F+PPDG
Sbjct: 213 GLND-KVLFDNTGRGKSKSVELEDVKFHQCVRLSRFE--ND------RTISFIPPDGEFE 263
Query: 314 LCQYTL 319
L Y L
Sbjct: 264 LMSYRL 269
>At1g56590 [U] KOG2740 Clathrin-associated protein medium chain
Length = 417
Score = 59.7 bits (143), Expect = 1e-08
Identities = 46/165 (27%), Positives = 83/165 (49%), Gaps = 17/165 (10%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVEK-GKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
S VPWR + Y++NE+++D+ EE++AIV + G+L+ I G + +N+ L+G P ++ L
Sbjct: 165 SCVPWRPTDPKYSSNEVYVDLVEEMDAIVNRDGELVKCEIYGEVQMNSQLTGFP--DLTL 222
Query: 267 GLLDHKLSHLNTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRLCQYTLPLVKRDS 326
+ + + FH C+ S L+FVPPDG +L Y + K +
Sbjct: 223 SFANPSILE-DMRFHPCVRYRPWES--------HQVLSFVPPDGEFKLMSYRCVVKKLKN 273
Query: 327 NLGIIDVNLQSSLGKRLDEFEVRVTVGM-STTVKEIENMSMTIRM 370
+ + S G + V VG+ S K IE+++++ ++
Sbjct: 274 TPVYVKPQITSDSG----TCRISVLVGIRSDPGKTIESITLSFQL 314
>CE28642 [U] KOG0938 Adaptor complexes medium subunit family
Length = 482
Score = 58.9 bits (141), Expect = 2e-08
Identities = 53/219 (24%), Positives = 99/219 (45%), Gaps = 45/219 (20%)
Query: 210 VPWRMSGINYANNEIFIDMSEEINAIV-EKGKLLTGHIKGCIDLNNHLSGQPLVEMKLGL 268
+ WR GI Y NE+F+D+ E +N ++ ++G++L+ H+ G + + ++LSG P E K G+
Sbjct: 163 IGWRREGIKYRRNELFLDVIEYVNLLMNQQGQVLSAHVAGKVAMKSYLSGMP--ECKFGI 220
Query: 269 LD---------------HKLSHL-----NTTFHRCILEDKANSINDLIAGKFTKLTFVPP 308
D +K S + FH+C+ K + + ++F+PP
Sbjct: 221 NDKITIEGKSKPGSDDPNKASRAAVAIDDCQFHQCVKLTKFETEH--------AISFIPP 272
Query: 309 DGRTRLCQY-----------TLPLVKRDS-NLGIIDVNLQSSLGKRL--DEFEVRVTVGM 354
DG L +Y +PLV+ S N + V ++S+ L + EVR+
Sbjct: 273 DGEYELMRYRTTKDIQLPFRVIPLVREVSRNKMEVKVVVKSNFKPSLLAQKLEVRIPTPP 332
Query: 355 STTVKEIENMSMTIRMNRNFKGIVRVMRNTHGGVETNMT 393
+T+ ++ M + IV ++ G E+ ++
Sbjct: 333 NTSGVQLICMKGKAKYKAGENAIVWKIKRMAGMKESQIS 371
>At1g60780 [U] KOG0937 Adaptor complexes medium subunit family
Length = 428
Score = 58.9 bits (141), Expect = 2e-08
Identities = 39/126 (30%), Positives = 59/126 (45%), Gaps = 24/126 (19%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIV-EKGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR GI Y NE+F+D+ E +N +V G+++ + G + + +L+G P E KL
Sbjct: 157 NAVSWRSEGIQYKKNEVFLDVIENVNILVNSNGQIVRSDVVGALKMRTYLTGMP--ECKL 214
Query: 267 GLLDHKLSHL-------------NTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTR 313
GL D L + FH+C+ A ND ++F+PPDG
Sbjct: 215 GLNDRVLLEAQGRATKGKAIDLEDIKFHQCV--RLARFEND------RTISFIPPDGAFD 266
Query: 314 LCQYTL 319
L Y L
Sbjct: 267 LMTYRL 272
>CE28050 [U] KOG0937 Adaptor complexes medium subunit family
Length = 422
Score = 58.2 bits (139), Expect = 3e-08
Identities = 37/128 (28%), Positives = 59/128 (45%), Gaps = 23/128 (17%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVE-KGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR GI Y NE+F+D+ E +N + G +L I G + + +L+G P E++L
Sbjct: 154 NAVSWRSEGIKYRKNEVFLDVIESVNMLASANGTVLQSEIVGSVKMRVYLTGMP--ELRL 211
Query: 267 GLLDHKLSH------------LNTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTRL 314
GL D L + FH+C+ + ++ ++F+PPDG L
Sbjct: 212 GLNDKVLFEGSGRGKSKSVELEDVKFHQCVRLSRFDTDR--------TISFIPPDGAFEL 263
Query: 315 CQYTLPLV 322
Y L V
Sbjct: 264 MSYRLTTV 271
>At5g46630 [U] KOG0938 Adaptor complexes medium subunit family
Length = 438
Score = 57.8 bits (138), Expect = 4e-08
Identities = 54/217 (24%), Positives = 94/217 (42%), Gaps = 43/217 (19%)
Query: 210 VPWRMSGINYANNEIFIDMSEEINAIV-EKGKLLTGHIKGCIDLNNHLSGQPLVEMKLGL 268
V WR G+ Y NE+F+D+ E +N ++ KG +L + G + + LSG P ++KLGL
Sbjct: 166 VGWRREGLAYKKNEVFLDIVESVNLLMSSKGNVLRCDVTGKVLMKCFLSGMP--DLKLGL 223
Query: 269 LD----HKLSHL--------------NTTFHRCILEDKANSINDLIAGKFTKLTFVPPDG 310
D K S + + TFH+C+ + NS ++FVPPDG
Sbjct: 224 NDKIGLEKESEMKSRPAKSGKTIELDDVTFHQCVNLTRFNSEK--------TVSFVPPDG 275
Query: 311 RTRLCQY-----------TLPLVKRDSNLGI-IDVNLQSSLGKRLDEF--EVRVTVGMST 356
L +Y LP +K + ++V ++S G ++ V++ V T
Sbjct: 276 EFELMKYRITEGVNLPFRVLPTIKELGRTRMEVNVKVKSVFGAKMFALGVVVKIPVPKQT 335
Query: 357 TVKEIENMSMTIRMNRNFKGIVRVMRNTHGGVETNMT 393
+ + + N + +V +R G E+ ++
Sbjct: 336 AKTNFQVTTGRAKYNPSIDCLVWKIRKFPGQTESTLS 372
>At1g10730 [U] KOG0937 Adaptor complexes medium subunit family
Length = 428
Score = 57.4 bits (137), Expect = 5e-08
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 24/126 (19%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIV-EKGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR G+ + NE+F+D+ E +N +V G+++ + G + + +LSG P E KL
Sbjct: 157 NSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMP--ECKL 214
Query: 267 GLLDHKLSHL-------------NTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTR 313
GL D L + FH+C+ A ND ++F+PPDG
Sbjct: 215 GLNDRILLEAQGRAIKGKAIDLEDIKFHQCV--RLARFEND------RTISFIPPDGSFD 266
Query: 314 LCQYTL 319
L Y L
Sbjct: 267 LMTYRL 272
>SPBP16F5.07 [U] KOG0937 Adaptor complexes medium subunit family
Length = 426
Score = 57.0 bits (136), Expect = 6e-08
Identities = 39/126 (30%), Positives = 59/126 (45%), Gaps = 24/126 (19%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAI-VEKGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ + WR GI+Y NE+F+D+ E +N I G ++ I G + L +LSG P E++L
Sbjct: 154 NAISWRSEGIHYRKNEVFLDVIESVNLIAAADGTVIQSEILGKVRLKCYLSGMP--ELRL 211
Query: 267 GLLDHKLSHL-------------NTTFHRCILEDKANSINDLIAGKFTKLTFVPPDGRTR 313
GL D L + FH+C+ A ND ++F+PPDG
Sbjct: 212 GLNDKVLFEAAGRTIKGNTVEMEDVKFHQCV--RLARFEND------RTISFIPPDGEFD 263
Query: 314 LCQYTL 319
L Y +
Sbjct: 264 LMSYRM 269
>YPL259c [U] KOG0937 Adaptor complexes medium subunit family
Length = 475
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/193 (26%), Positives = 80/193 (40%), Gaps = 42/193 (21%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIV-EKGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR GI + NE F+D+ E IN ++ +KG++L I G + +N+ LSG P ++KL
Sbjct: 162 NSVSWRPEGITHKKNEAFLDIVESINMLMTQKGQVLRSEIIGDVKVNSKLSGMP--DLKL 219
Query: 267 GLLDHKL------------SHLNTTFHRCILEDKANSINDLIAGKFTK------------ 302
G+ D + S TT DK SI A K
Sbjct: 220 GINDKGIFSKYLDDDTNIPSASATTSDNNTETDKKPSITSSSATNKKKVNIELEDLKFHQ 279
Query: 303 ------------LTFVPPDGRTRLCQYTLPLVKRDSNLGIIDVNLQSSLGKRLD-EFEVR 349
+TF+PPDG+ L Y L + L DVN+Q R++ + +
Sbjct: 280 CVRLSKFENEKIITFIPPDGKFDLMNYRLSTTIKP--LIWCDVNVQVHSNSRIEIHCKAK 337
Query: 350 VTVGMSTTVKEIE 362
+ +T +E
Sbjct: 338 AQIKRKSTATNVE 350
>CE11129 [U] KOG0937 Adaptor complexes medium subunit family
Length = 470
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/122 (31%), Positives = 55/122 (44%), Gaps = 12/122 (9%)
Query: 208 SGVPWRMSGINYANNEIFIDMSEEINAIVE-KGKLLTGHIKGCIDLNNHLSGQPLVEMKL 266
+ V WR GI Y NE+F+D+ E +N + +G +L I G I LSG P E++L
Sbjct: 153 NAVSWRSEGIKYRKNEVFLDVIESVNMLANAQGTVLRSEIVGSIRFRVVLSGMP--ELRL 210
Query: 267 GLLDHKLSHLNTTFHRCILEDKANSINDLIAGKFTKL---------TFVPPDGRTRLCQY 317
GL D + R K + D+ + +L +F+PPDG L Y
Sbjct: 211 GLNDKVFFQQSGASSRRGNSGKGVELEDIKFHQCVRLSRFDSERTISFIPPDGEFELMSY 270
Query: 318 TL 319
L
Sbjct: 271 RL 272
>SPAC31A2.09c [U] KOG0938 Adaptor complexes medium subunit family
Length = 446
Score = 55.1 bits (131), Expect = 2e-07
Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 39/136 (28%)
Query: 210 VPWRMSGINYANNEIFIDMSEEINAIVEK-GKLLTGHIKGCIDLNNHLSGQPLVEMKLGL 268
VPWR +GI Y N I+ID+ E +N ++ G +L + G + + LSG P E + GL
Sbjct: 166 VPWRRAGIKYRKNSIYIDIVERMNLLISSTGNVLRSDVSGVVKMRAMLSGMP--ECQFGL 223
Query: 269 ---LDHKLSHLNT-----------------------TFHRCI-LEDKANSINDLIAGKFT 301
LD KL + FH+C+ L + N
Sbjct: 224 NDKLDFKLKQSESKSKSNNSRNPSSVNGGFVILEDCQFHQCVRLPEFENE---------H 274
Query: 302 KLTFVPPDGRTRLCQY 317
++TF+PPDG L Y
Sbjct: 275 RITFIPPDGEVELMSY 290
>YOL062c [U] KOG0938 Adaptor complexes medium subunit family
Length = 491
Score = 53.9 bits (128), Expect = 5e-07
Identities = 41/146 (28%), Positives = 62/146 (42%), Gaps = 42/146 (28%)
Query: 206 DESGVPWRMSGINYANNEIFIDMSEEINAIVEK-GKLLTGHIKGCIDLNNHLSGQPLVEM 264
D + + WR GI + +E+F+ ++E IN +V + G +L ++ G ID+ HLSG P+
Sbjct: 194 DNNKITWRPKGIIHKKDEVFLYVNERINILVSRDGSILKSYVDGTIDITTHLSGTPICRF 253
Query: 265 ----KLGL--------LDHKLSHLNT---------------------TFHRCILEDKANS 291
LG+ L + H + FH C+ DK N
Sbjct: 254 GLNDSLGMQSEDEKKWLAQQQRHSGSDFGNKNFIPKAAAGSVLLEDCKFHECVSLDKFNR 313
Query: 292 INDLIAGKFTKLTFVPPDGRTRLCQY 317
N +I FVPPDG L +Y
Sbjct: 314 -NHII-------EFVPPDGSMELMKY 331
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,985,977
Number of Sequences: 60738
Number of extensions: 988256
Number of successful extensions: 1913
Number of sequences better than 1.0e-05: 22
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1848
Number of HSP's gapped (non-prelim): 49
length of query: 497
length of database: 30,389,216
effective HSP length: 111
effective length of query: 386
effective length of database: 23,647,298
effective search space: 9127857028
effective search space used: 9127857028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)