ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4884 good U KOG1299 Intracellular trafficking, secretion, and vesicular transport Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4884 1674074 1672344 -577
(577 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL095c [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 f... 584 e-166
SPAC2G11.03c [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (S... 335 1e-91
7299206 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 f... 314 2e-85
Hs18105063 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec... 313 6e-85
At1g77140 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1... 286 6e-77
CE04214 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 f... 236 7e-62
ECU06g1460 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec... 102 1e-21
YDR189w [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family) 99 1e-20
Hs5902128 [U] KOG1300 Vesicle trafficking protein Sec1 99 2e-20
Hs4507297 [U] KOG1300 Vesicle trafficking protein Sec1 92 2e-18
CE17219 [U] KOG1300 Vesicle trafficking protein Sec1 89 1e-17
SPCC74.01 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fam... 88 3e-17
Hs7706371 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fam... 83 1e-15
Hs7706407 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fam... 81 4e-15
Hs6005886 [U] KOG1300 Vesicle trafficking protein Sec1 80 8e-15
At4g12120 [U] KOG1300 Vesicle trafficking protein Sec1 76 2e-13
CE24927 [U] KOG1300 Vesicle trafficking protein Sec1 72 2e-12
At1g12360 [U] KOG1300 Vesicle trafficking protein Sec1 70 7e-12
7295949 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family) 70 1e-11
7292440 [U] KOG1300 Vesicle trafficking protein Sec1 69 3e-11
At1g02010 [U] KOG1300 Vesicle trafficking protein Sec1 67 7e-11
ECU03g0900 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fa... 64 6e-10
SPCC584.05 [U] KOG1300 Vesicle trafficking protein Sec1 60 9e-09
At2g17980 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fam... 59 2e-08
CE00993 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family) 59 2e-08
>YGL095c [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Length = 577
Score = 584 bits (1505), Expect = e-166
Identities = 291/580 (50%), Positives = 404/580 (69%), Gaps = 21/580 (3%)
Query: 1 MNLFTVGDYYISRIANFQSKPSDTSIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIY 60
MNLF V D+YI++I QSK S ++ E R+K L+LD +T TIS+C TQ+ELLKHEIY
Sbjct: 1 MNLFDVADFYINKIVTSQSKLSVANVNEHQRIKVLLLDKNTTPTISLCATQSELLKHEIY 60
Query: 61 LVDKLENIHRDPMPHLKCLCYLKPTEDTIQDLLHELQDPKYGEYQIFFNNQVSKSQLERL 120
LV+++EN R+ HL+CL Y+KPTE+T+Q LL EL++P+YGEYQIFF+N VSKSQLERL
Sbjct: 61 LVERIENEQREVSRHLRCLVYVKPTEETLQHLLRELRNPRYGEYQIFFSNIVSKSQLERL 120
Query: 121 AERDDMEVVTHVEEVFQDYLIVNEDVFTLEIPLYNLLQNQLVWDPKGLQETSNGXXXXXX 180
AE DD+E VT VEE+FQD+ I+N+D+F+ ++ L N+LVW GL + +N
Sbjct: 121 AESDDLEAVTKVEEIFQDFFILNQDLFSFDLQPREFLSNKLVWSEGGLTKCTNSLVSVLL 180
Query: 181 XXXXNPTIAYDSDSKLCQKLAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPL 240
P I Y+ SK+C++LAK++ YEI NER FDFPV DS P+L++LDR +DP+TPL
Sbjct: 181 SLKIKPDIRYEGASKICERLAKEVSYEIGKNERTFFDFPVMDSTPVLLILDRNTDPITPL 240
Query: 241 LQPWTYQSMINEYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADK 300
LQPWTYQSMINEYIGIKRN+VDLS VP ID DL++V LSSKQD FF++TMY+NFG+L DK
Sbjct: 241 LQPWTYQSMINEYIGIKRNIVDLSKVPRIDKDLEKVTLSSKQDAFFRDTMYLNFGELGDK 300
Query: 301 VKNYVTQYKNKTNITKQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNI 360
VK YVT YK+KT QIN+ LSGN++KHMAIV ELDRQL++KNI
Sbjct: 301 VKQYVTTYKDKTQTNSQINSIEDIKNFIEKYPEFRKLSGNVAKHMAIVGELDRQLKIKNI 360
Query: 361 WEVSELEQNLSSHDDNNDDFVELKRILNLPTLESYYKLKLCCIFVLRHGKNESRVSELEN 420
WE+SE+EQNLS+HD N +DF +L ++L ++ YYKLKL CI+ L + + ++ +L
Sbjct: 361 WEISEIEQNLSAHDANEEDFSDLIKLLQNEAVDKYYKLKLACIYSLNNQTSSDKIRQLVE 420
Query: 421 ILRQQCDPTQISLYFQFKQRFGSIFNKHKAPQD-NDLISGLTKKFN-RLGSTS--AENVF 476
IL QQ P ++ + +FK F ++ D +D+++ L ++FN R+ S S AENV+
Sbjct: 421 ILSQQLPPEDVNFFHKFKSLFSRQDKMTQSNHDKDDILTELARRFNSRMNSKSNTAENVY 480
Query: 477 MQHVPELTTLLSDLDKNKFPQEGVTLLNQNIDPKTY----------MPQDVVILIVGGLT 526
MQH+PE+++LL+DL KN ++ + ID + + +PQDV++ ++GG+T
Sbjct: 481 MQHIPEISSLLTDLSKNALFRDRF----KEIDTQGHRVIGNQQSKDIPQDVILFVIGGVT 536
Query: 527 IEEARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDV 566
EEAR VH FN + + RV++GGTSI+ST++++ +
Sbjct: 537 YEEARLVHDFNGTMN---NRMRVVLGGTSILSTKEYMDSI 573
>SPAC2G11.03c [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Length = 558
Score = 335 bits (859), Expect = 1e-91
Identities = 202/571 (35%), Positives = 317/571 (55%), Gaps = 26/571 (4%)
Query: 1 MNLFTVGDYYISRIANFQSKPSDTSIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIY 60
M+L + Y RI QE S +K L+L+ DT +S C TQ+ LL+ +IY
Sbjct: 1 MDLVSASQSYFKRI-----------FQEVSDLKILLLEEDTTKIVSSCITQSNLLEQQIY 49
Query: 61 LVDKLENIHRDPMPHLKCLCYLKPTEDTIQDLLHELQDPKYGEYQIFFNNQVSKSQLERL 120
L L N R+ + HLKC+ +L+PT T++ L EL+DPKY EY ++F N + KS LERL
Sbjct: 50 LTVLLGN-KREKLRHLKCVAFLRPTPTTLRLLCEELRDPKYAEYHLYFTNVIPKSFLERL 108
Query: 121 AERDDMEVVTHVEEVFQDYLIVNEDVFTLEIPLYNLLQNQLVWDPKGLQETSNGXXXXXX 180
AE DD E V ++E F DYL+VN D+ + IP + + + W T G
Sbjct: 109 AESDDFEAVKSIQEFFLDYLVVNNDLASFNIP-HIIEDSPDNWQDGAFHRTHQGIISLLL 167
Query: 181 XXXXNPTIAYDSDSKLCQKLAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPL 240
P I YD++S LC KLA+++ Y I+ +E QLF+F D+ P+L+LLDRK+DP+TPL
Sbjct: 168 SLKKKPVIRYDNNSLLCLKLAEEVSYTIQ-HESQLFNFRKPDTAPILLLLDRKNDPITPL 226
Query: 241 LQPWTYQSMINEYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADK 300
L WTYQ+M++E GI V SN + + ++VL+ D F+KET + NFGDL K
Sbjct: 227 LTQWTYQAMVHELFGIDNGRVSFSNSTSDNEKSTEIVLNPTLDPFYKETRFDNFGDLGVK 286
Query: 301 VKNYVTQYKNK-TNITKQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKN 359
+K+YV+ + K T +I + LSGN+SKH+++VSE+ + +Q +N
Sbjct: 287 IKDYVSHLQTKSTKKASEIESIADMKQFLEAYPEYRRLSGNVSKHVSLVSEISQVVQREN 346
Query: 360 IWEVSELEQNLSSHDDNNDDFVELKRILNLPTLESYYKLKLCCIFVLRHGK-NESRVSEL 418
+ EV E+EQ+L ++ + DF +++R+L + KL+L ++ LR + + ++VS L
Sbjct: 347 LLEVGEVEQSLVCNEPQSTDFNDIQRLL-FSNISENTKLRLAALYSLRFERIDPAKVSAL 405
Query: 419 ENIL-RQQCDPTQISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFM 477
+ +L +P ++S+ G F + ++L S + G ENV++
Sbjct: 406 QQMLIAGGVNPLKVSVIPTLLHVAGYSFRQGDVFPPSNLFS--RARSGLKGLRGVENVYI 463
Query: 478 QHVPELTTLLSDLDKNKFPQEGVTLLNQNIDPKT--YMPQDVVILIVGGLTIEEARAVHQ 535
QH P L ++L DL + + + LN +T PQD++++IVGG T EEA V +
Sbjct: 464 QHNPFLKSILLDLIQGRLKETTHPFLNSETRAQTSNEKPQDIIVVIVGGATYEEAHFVSE 523
Query: 536 FNEKQSKNKDNCRVIIGGTSIISTEQFLTDV 566
FN Q R+I+ GT+I+++ ++ D+
Sbjct: 524 FNATQ----PGVRIILAGTTILNSTAYIDDI 550
>7299206 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Length = 574
Score = 314 bits (805), Expect = 2e-85
Identities = 197/578 (34%), Positives = 311/578 (53%), Gaps = 36/578 (6%)
Query: 1 MNLFTVGDYYISRIANFQSKPSDTSIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIY 60
MNL + YI ++ + +S P +K ++LD +T S ISM +Q+++L+ E+Y
Sbjct: 1 MNLISGIKLYIEKMCS-ESGPG---------MKIILLDKETTSIISMAFSQSDMLQREVY 50
Query: 61 LVDKLENIH-RDPMPHLKCLCYLKPTEDTIQDLLHELQDPKYGEYQIFFNNQVSKSQLER 119
L ++L++ + + +LKC+ +++PT+ IQ L +EL++PKY Y I+F+N + ++ ++
Sbjct: 51 LFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANELRNPKYSAYYIYFSNIIPRTDIKY 110
Query: 120 LAERDDMEVVTHVEEVFQDYLIVNEDVFTLEIPLYNLLQNQLVWDPKGLQETSNGXXXXX 179
LAE D+ E V V+E++ DYL VN ++F+L IP N + N L W P L + G
Sbjct: 111 LAECDESESVREVKELYADYLCVNPNLFSLGIP--NCMAN-LNWLPDALNRSMQGITAVL 167
Query: 180 XXXXXNPTIAYDSDSKLCQKLAKDLEYEIKTNERQLFDFPVRDSN---PLLILLDRKSDP 236
NP I Y + S+ Q LAK L YE T E LFDF PLL++LDR+ DP
Sbjct: 168 LSLKLNPVIRYRAGSQAAQLLAK-LIYEQITKESSLFDFRSNMDGAAPPLLLVLDRRDDP 226
Query: 237 LTPLLQPWTYQSMINEYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGD 296
+TPLL WTYQ+M++E + IK N +DLSN PN+ D K++VLS QD F+ MY N+G+
Sbjct: 227 VTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVPKDFKELVLSGDQDDFYGNNMYANYGE 286
Query: 297 LADKVKNYVTQYKNKTNITKQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQ 356
+ +K + +++ K N K++ + +SG + KH+ ++ EL
Sbjct: 287 IGSTIKQLMEEFQRKANDHKKVESIADMKNFIESYPQFKKMSGTVQKHLCVIGELSALSN 346
Query: 357 LKNIWEVSELEQNLSSHDDNNDDFVELKRILNLPTLESYYKLKLCCIFVLRHGKNES-RV 415
+N++EVSELEQ ++ +++ +K+++ + LKL ++ LR+ ++ +
Sbjct: 347 KRNLFEVSELEQEIACKAEHSAQLQRIKKLIADERVSIDDALKLVALYALRYERHANCDT 406
Query: 416 SELENIL-----RQQCDPTQISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGST 470
S L I+ R P+ I Y R G +FN + L L K G
Sbjct: 407 SGLLQIIKTRGGRAAIVPSLIE-YAGTHVRQGDLFNMVRITDAVKLTRNLIK-----GLK 460
Query: 471 SAENVFMQHVPELTTLLSDLDKNKFPQEGVTLLNQNIDPKTYMPQDVVILIVGGLTIEEA 530
ENVF QH P L L D+ K + +N + P PQ+VV+ I+GG T EEA
Sbjct: 461 GVENVFTQHTPLLKETLEDVFKGRELDPLFPAINSELVPFRRPPQEVVVFIIGGATYEEA 520
Query: 531 RAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDVCA 568
AVHQ N K VI+GGT+I +++ F+ +V A
Sbjct: 521 LAVHQLNNAGYK------VILGGTTIHNSQSFIQEVVA 552
>Hs18105063 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Length = 570
Score = 313 bits (801), Expect = 6e-85
Identities = 180/546 (32%), Positives = 303/546 (54%), Gaps = 27/546 (4%)
Query: 32 VKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQD 91
+K L++D +T +SM TQ+E+L+ E+YL +++++ +R+ M HLK +C+L+PT++ +
Sbjct: 22 MKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDY 81
Query: 92 LLHELQDPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVNEDVFTLEI 151
++ EL+ PKY Y I+F+N +SKS ++ LAE D+ EVV V+E + DY+ VN +F+L I
Sbjct: 82 IIQELRRPKYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNI 141
Query: 152 PLYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLAKDLEYEIKTN 211
Q + WDP L T+ G P I Y S+ ++LA+ ++ ++ T
Sbjct: 142 --LGCCQGR-NWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVK-QVITK 197
Query: 212 ERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRNLVDLSNVPNIDP 271
E +LF+F + PLL++LDR D +TPLL WTYQ+M++E +GI N +DLS VP I
Sbjct: 198 EYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISK 257
Query: 272 DLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQY-KNKTNITKQINTXXXXXXXXXX 330
DL++VVLS++ D+F+ MY+NF ++ +KN + + K K +++ +
Sbjct: 258 DLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVEN 317
Query: 331 XXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNNDDFVELKRILNLP 390
+SG +SKH+ +V EL R + +N+ EVSE+EQ L+ +D++ +KR+L P
Sbjct: 318 YPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNP 377
Query: 391 TLESYYKLKLCCIFVLRHGKNESR-VSELENILRQQCDPTQISLYFQFKQRFGSIFNKHK 449
+ + +L ++ L + ++ S + L LR + + +G K
Sbjct: 378 KVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLVSAVVEYGG-----K 432
Query: 450 APQDNDLIS-----GLTKKFNRLGSTSAENVFMQHVPELTTLLSDLDKNKFPQEGVTLLN 504
+ +DL S +TK+F + G ENV+ QH P L L L K + + L
Sbjct: 433 RVRGSDLFSPKDAVAITKQFLK-GLKGVENVYTQHQPFLHETLDHLIKGRLKEN----LY 487
Query: 505 QNIDPKTY--MPQDVVILIVGGLTIEEARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQF 562
+ P T PQD+++ ++GG T EEA V+ N + R+++GGT++ +T+ F
Sbjct: 488 PYLGPSTLRDRPQDIIVFVIGGATYEEALTVYNLN----RTTPGVRIVLGGTTVHNTKSF 543
Query: 563 LTDVCA 568
L +V A
Sbjct: 544 LEEVLA 549
>At1g77140 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Length = 550
Score = 286 bits (732), Expect = 6e-77
Identities = 173/550 (31%), Positives = 303/550 (54%), Gaps = 28/550 (5%)
Query: 26 IQEKSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIH--RDPMPHLKCLCYLK 83
+Q+ S +K LILD++T+S +S+ +Q+ELL+ E++LV+ +++I ++ M HLK + +++
Sbjct: 15 LQDISGMKVLILDSETVSNVSIVYSQSELLQKEVFLVEMIDSISVSKESMSHLKAVYFIR 74
Query: 84 PTEDTIQDLLHELQDPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVN 143
PT D IQ L ++L +P++GEY +FF+N + +Q+ LA+ D+ EVV V+E + D++ +
Sbjct: 75 PTSDNIQKLRYQLANPRFGEYHLFFSNLLKDTQIHILADSDEQEVVQQVQEYYADFVSGD 134
Query: 144 EDVFTLEIPLYNLLQNQLVWDPKGLQETS----NGXXXXXXXXXXNPTIAYDSDSKLCQK 199
FTL + +L V DP GLQ S +G P I Y S ++
Sbjct: 135 PYHFTLNMASNHLYMIPAVVDPSGLQRFSDRVVDGIAAVFLALKRRPVIRYQRTSDTAKR 194
Query: 200 LAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRN 259
+A + + +E LFDF +S+PLL+++DR+ DP+TPLL WTYQ+M++E IG++ N
Sbjct: 195 IAHETAKLMYQHESALFDFRRTESSPLLLVIDRRDDPVTPLLNQWTYQAMVHELIGLQDN 254
Query: 260 LVDLSNVPNIDPDLK-QVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNITKQI 318
VDL ++ ++ D + +VVLSS+QD FFK MY NFGD+ +K V ++ + I
Sbjct: 255 KVDLKSIGSLPKDQQVEVVLSSEQDAFFKSNMYENFGDIGMNIKRMVDDFQQVAKSNQNI 314
Query: 319 NTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNND 378
T + GN+SKH+ +V+E+ + ++ + + VS+ EQ+L+ +
Sbjct: 315 QTVEDMARFVDNYPEYKKMQGNVSKHVTLVTEMSKLVEARKLMTVSQTEQDLACNGGQGA 374
Query: 379 DFVELKRILNLPTLESYYKLKLCCIFVLRHGK-NESRVSELENILRQQCDPTQISL-YFQ 436
+ + +LN ++ +L+L ++ LR+ K N ++ +L N L + + L F
Sbjct: 375 AYEAVTDLLNNESVSDIDRLRLVMLYALRYEKENPVQLMQLFNKLASRSPKYKPGLVQFL 434
Query: 437 FKQ-----RFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFMQHVPELTTLLSDLD 491
KQ R G +F + DL++ + + R G ENV+ QH P L + +
Sbjct: 435 LKQAGVEKRTGDLFG------NRDLLN-IARNMAR-GLKGVENVYTQHQPLLFQTMESIT 486
Query: 492 KNKFPQEGVTLLNQNIDPKTYMPQDVVILIVGGLTIEEARAVHQFNEKQSKNKDNCRVII 551
+ + + + + PQ+VVI +VGG T EE+R+V Q+ R I+
Sbjct: 487 RGRLRDVDYPFVGDHF--QQGRPQEVVIFMVGGTTYEESRSV----ALQNATNSGVRFIL 540
Query: 552 GGTSIISTEQ 561
GGT+++++++
Sbjct: 541 GGTAVLNSKR 550
>CE04214 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Length = 547
Score = 236 bits (602), Expect = 7e-62
Identities = 144/543 (26%), Positives = 276/543 (50%), Gaps = 24/543 (4%)
Query: 30 SRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLEN-IHRDPMPHLKCLCYLKPTEDT 88
S++K L++D +T T+S Q+E+++ E+Y+ D++EN + + +LKC+ +++PT
Sbjct: 20 SQMKLLLMDGETTPTVSCAFAQSEVMQKEVYIFDRIENKTSSENIKNLKCVVFVRPTPKN 79
Query: 89 IQDLLHELQDPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVNEDVFT 148
I+ L+ ELQ+P++ +Y ++F N ++K ++RLAE D E V V+EVF D + + +D+FT
Sbjct: 80 IERLVKELQEPRFSQYYLYFTNTINKYDVKRLAEADKNETVREVQEVFLDGVPIRKDLFT 139
Query: 149 LEIPLYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLAKDLEYEI 208
L L ++ + + + G P + Y S C+K+A D+ I
Sbjct: 140 LN--LTHIFDSSFTLKEEAAERIKCGIIALLLQLKKAPAVRYQKSSPSCKKVADDVAQFI 197
Query: 209 KTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRNLVDLSNVPN 268
+ E LF+ D+ L++++R D +TPLL WTY++MI+E + + N ++
Sbjct: 198 R-RENGLFENSRADTT--LLIIERSQDAVTPLLNQWTYEAMIHEMLTLTNNRCTCTD--- 251
Query: 269 IDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNITKQINTXXXXXXXX 328
+ +VLS D+FF + NFG++ +K +++++ K +I K + +
Sbjct: 252 -----QNIVLSELHDEFFARNITANFGEIGQNIKTLISEFQEKKHINKNLESIQDMKKFV 306
Query: 329 XXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNNDDFVELKRILN 388
+SG +SKH+++V EL +Q N+ VSE+EQ + S D+ ++ +L
Sbjct: 307 EDYPQFKKISGTVSKHVSLVGELSNLVQKHNLLGVSEVEQAIVSDGDHGKCINLVRGLLK 366
Query: 389 LPTLESYYKLKLCCIFVLRHGKNESRVSELENILRQ-QCDPTQISLYFQFKQRFGSIFNK 447
++L ++ LR + +EL +++ Q + +I ++G + +
Sbjct: 367 NTKTREVDIIRLVLLYALRF--ENAPGNELNSLISQLRPQHPKIHQTVSTLLKYGGLSRR 424
Query: 448 HKAPQDNDLISGLTKKFNRLGSTSAENVFMQHVPELTTLLSDLDKNKFPQEGVTLLNQNI 507
+ +TK+F + G EN++ QH P L ++ + + + LL+
Sbjct: 425 PADLFGGESTIDITKRFIK-GLKGVENIYTQHSPYLKNMIESCQRGRL--DNYPLLSNEC 481
Query: 508 DPKTYMPQDVVILIVGGLTIEEARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDVC 567
D ++++ IVGG T EEA V NEK+ + V++ G+S+++T+ FL +
Sbjct: 482 D----RMDNIIVFIVGGATYEEAAYVRSLNEKRMQGYGGPAVVLAGSSMLNTKSFLEEFA 537
Query: 568 AVN 570
V+
Sbjct: 538 NVD 540
>ECU06g1460 [U] KOG1299 Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
Length = 490
Score = 102 bits (255), Expect = 1e-21
Identities = 115/543 (21%), Positives = 221/543 (40%), Gaps = 79/543 (14%)
Query: 16 NFQSKPSDTSIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPH 75
N K D + VK L+ D DT +S + L+ + +L D + N R+ +
Sbjct: 4 NLLGKKVDEILDIGEGVKVLLFDEDTKMILSNLIPHSRFLESDYFLFDSIMNKRRERIQG 63
Query: 76 LKCLCYLKPTEDTIQDLLHELQDPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEV 135
+ C+ ++P ++I+ L+ E+ +P Y Y + F NQV LE LA D VV+ + E+
Sbjct: 64 ITCMVAIRP--ESIRWLIEEVSNPFYERYIVLFTNQVDSLMLEILATSDVHCVVSEIHEI 121
Query: 136 FQDYLIVNEDVFTLEIPLYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSK 195
+ D+ ++ ++TL P + + G + + +G PTI ++ +
Sbjct: 122 YIDFFKQDDFLYTLHAP-----KTREHMSLSGRKRSIDGIFALVMNLGRIPTIKIQTEDR 176
Query: 196 LCQKLAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIG 255
L +D E T +L ++ LI+LDR D TPLL W YQS+++E+
Sbjct: 177 ---HLMEDSE----TLSTRLAGLNLKQGG-TLIMLDRAFDLYTPLLYEWRYQSLLHEHAD 228
Query: 256 IKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNIT 315
+V + + S D FF + + + ++++ +K V K
Sbjct: 229 YANGIVRIG----------KKSYSVADDPFFNASKFKDIYEVSEDIKGLV----KKVEFK 274
Query: 316 KQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDD 375
K+ L ++++H ++ L+LK ++SE+E N+ D
Sbjct: 275 KKRLHNFIFDDLEENTRISRQLEAHLAQHGHVMKAC---LRLK---DLSEMEMNVLK--D 326
Query: 376 NNDDFVELKRILNLPTLESYYKLKLCCIFVLRHGKN---ESR-----VSELENILRQQCD 427
N E+ L + + KL I+ LR+ KN E+R ++E+E + +
Sbjct: 327 NGVSKAEISECLTRKDISVIERCKLLIIYSLRNKKNPIDEARKYPDLMNEVEAFMGRH-- 384
Query: 428 PTQISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFMQHVPELTTLL 487
P + ++ + RF D+D+ +V + + P + ++
Sbjct: 385 PLNVPIWRHYGYRF-----------DDDV-----------------DVKLGYQPAIKRVI 416
Query: 488 SDLDKNKFPQEGVTLLNQNIDPKTYMPQDVVILIVGGLTIEEARAVHQFNEKQSKNKDNC 547
N+ + ++ +P Y +V+ I G+T E R + ++ K +
Sbjct: 417 RHWWTNRLDNRCFLTVRESENPMDY----IVVYIRNGVTYSEYRVLCEYYNTAMKGRSEL 472
Query: 548 RVI 550
V+
Sbjct: 473 YVV 475
>YDR189w [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 666
Score = 99.4 bits (246), Expect = 1e-20
Identities = 133/625 (21%), Positives = 240/625 (38%), Gaps = 82/625 (13%)
Query: 16 NFQSKPSDTSIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPH 75
N + D Q++ K LILD + +TIS +LLK I V L R P+P
Sbjct: 37 NITTITDDIFNQQEIIWKVLILDIKSTATISSVLRVNDLLKAGI-TVHSLIKQDRSPLPD 95
Query: 76 LKCLCYLKPTEDTIQDLLHELQDPKYGEYQIFFNNQVSKSQLERLAERDDM----EVVTH 131
+ + ++ PT++ I ++++L+ KY E+ I F + + ++ LE LA++ + + +
Sbjct: 96 VPAIYFVSPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQ 155
Query: 132 VEEVFQDYLIVNEDVFTLEIPLYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYD 191
V + + D+++ ++F+LEI L N DPK +E G N + +
Sbjct: 156 VYDQYLDFIVTEPELFSLEISNAYLTLN----DPKTTEEEITGLCANIADGLFNTVLTIN 211
Query: 192 S-----------DSKLCQKLAKDL-EYEIKTNERQLFDFPVRDS--NPLLILLDRKSDPL 237
S + +KL L ++ I TN DS +LI+LDR D
Sbjct: 212 SIPIIRAAKGGPAEIIAEKLGTKLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFA 271
Query: 238 TPLLQPWTYQSMINEYIGIKRNLV--DLSNVPNIDPDLKQVVLSSKQ------DKFFKET 289
+ W YQ M+ + + RN V L + N + L++K+ D F+ E
Sbjct: 272 SMFSHSWIYQCMVFDIFKLSRNTVTIPLESKENGTDNTTAKPLATKKYDIEPNDFFWMEN 331
Query: 290 MYMNFGDLADKVKNYVTQYK-------NKTNIT-------KQINTXXXXXXXXXXXXXXX 335
++ F + A+ V+ + YK KT +T N
Sbjct: 332 SHLPFPEAAENVEAALNTYKEEAAEITRKTGVTNISDLDPNSNNDTVQIQEVVKKLPELT 391
Query: 336 XLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNNDDFVELKRILNLPTLESY 395
I HM I + L QL+ K++ E+EQ+ S F+++ + LE
Sbjct: 392 AKKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGS-TKTRSRFLDILKDGKTNNLEDK 450
Query: 396 YKLKLCCIFVLRHGKNESRVSELENILRQQCDPTQISLYFQFKQRFGSIFN---KHKAPQ 452
+ + G + V +EN ++ Y + F + N ++K+ +
Sbjct: 451 LRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQNKSLE 510
Query: 453 D----------------------------NDLISGLTK---KFNRLGSTSAENVFMQHVP 481
D LISG+ K + + T+ + M +
Sbjct: 511 DGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIMDPLN 570
Query: 482 ELTTLLSDLDKNKFPQEGVTLLNQNIDPKTYMPQDVVILIVGGLTIEEARAVHQFNEKQS 541
L D + +T + PK ++ +VGG E + + ++ Q
Sbjct: 571 SSQKNLETTDSYLYIDPKITRGSHTRKPKRQSYNKSLVFVVGGGNYLEYQNLQEWAHSQL 630
Query: 542 KNKDNCRVIIGGTSIISTEQFLTDV 566
N +V+ G T+I + +FL ++
Sbjct: 631 HNPK--KVMYGSTAITTPAEFLNEI 653
>Hs5902128 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 593
Score = 99.0 bits (245), Expect = 2e-20
Identities = 118/588 (20%), Positives = 245/588 (41%), Gaps = 54/588 (9%)
Query: 25 SIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKP 84
S+++ K LI+D+ ++ +S C +++L I +V+ + N R+P+P L+ + L P
Sbjct: 21 SVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDI-NKRREPIPSLEAIYLLSP 79
Query: 85 TEDTIQDLLHELQDPKYGEYQ---IFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLI 141
TE ++Q L+ + Q Y+ IFF + + L +VV ++E+ +L
Sbjct: 80 TEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRLAKVVKTLKEIHLAFLP 139
Query: 142 VNEDVFTLEIP--LYNLLQNQLVWD-PKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQ 198
VF+L+ P YNL + + L+ + P I Y +
Sbjct: 140 YEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLCATLQEYPAIRYRKGPEDTA 199
Query: 199 KLAKDLEYEI---KTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIG 255
+LA + ++ K + L + P + + LLI+ DR +DP++PLL T+Q+M + +
Sbjct: 200 QLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIM-DRAADPVSPLLHELTFQAMAYDLLD 258
Query: 256 IKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNIT 315
I+++ + ++ VL + D + E +M+ D++ KV + + +T
Sbjct: 259 IEQDTYRYETT-GLSEAREKAVLLDEDDDLWVELRHMHIADVSKKVTELLRTFCESKRLT 317
Query: 316 KQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDD 375
S H+ + + + + ++ ++ +EQ+L+ D
Sbjct: 318 TDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFK-GSVEKLCSVEQDLAMGSD 376
Query: 376 NNDDFVELKRILNLPTL-----ESYYKLKLCCIFV-LRHGKNESRVSELENILRQQCDPT 429
+ ++ L +P L +Y K+++ +++ LR+G +E +++L Q
Sbjct: 377 AEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSEENLAKLIQHANVQ---A 433
Query: 430 QISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFMQHVPELTTLLSD 489
SL +Q G++ N SG + + + P + ++ D
Sbjct: 434 HSSLIRNLEQLGGTVTNPGG--------SGTSSRLEPRERMEPTYQLSRWTPVIKDVMED 485
Query: 490 -----LDKNKFP-----------QEGVTLL-----NQNIDPKTYMPQDVVILIVGGLTIE 528
LD+N +P Q V+ + +++ ++GG+ +
Sbjct: 486 AVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGVEARAGPRLIVYVMGGVAMS 545
Query: 529 EARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDVCAVNDKPVDL 576
E RA + E + V+IG + I++ +FL D+ A++ K D+
Sbjct: 546 EMRAAY---EVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDI 590
>Hs4507297 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 603
Score = 92.0 bits (227), Expect = 2e-18
Identities = 108/577 (18%), Positives = 241/577 (41%), Gaps = 52/577 (9%)
Query: 26 IQEKSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPT 85
+++K K L++D ++ +S C T+++ I +V+ + N R+P+P L+ + + P+
Sbjct: 22 VKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDI-NKRREPLPSLEAVYLITPS 80
Query: 86 EDTIQDLLHELQDP---KYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIV 142
E ++ L+ + +DP KY +FF + + L + +V+ + E+ +L
Sbjct: 81 EKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPY 140
Query: 143 NEDVFTLE---------IPLYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYD-- 191
V++L+ P ++N + L+ + P + Y
Sbjct: 141 ESQVYSLDSADSFQSFYSPHKAQMKNPI------LERLAEQIATLCATLKEYPAVRYRGE 194
Query: 192 -SDSKLCQKLAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMI 250
D+ L +L +D K ++ + + P + + LLI LDR DP +P+L T+Q+M
Sbjct: 195 YKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLI-LDRGFDPSSPVLHELTFQAMS 253
Query: 251 NEYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKN 310
+ + I+ ++ + +K+V+L + D + + + +++ +V + + +
Sbjct: 254 YDLLPIENDVYKYETSGIGEARVKEVLL-DEDDDLWIALRHKHIAEVSQEVTRSLKDFSS 312
Query: 311 KTNI-TKQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQN 369
+ T + T S H+ + + + Q + ++ +EQ+
Sbjct: 313 SKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQ-GTVDKLCRVEQD 371
Query: 370 LSSHDDNNDDFVE-----LKRILNLPTLESYYKLKLCCIFV-LRHGKNESRVSELENILR 423
L+ D + ++ + IL + +Y K+++ +++ L++G E +++L I
Sbjct: 372 LAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKL--IQH 429
Query: 424 QQCDPTQISLYFQFKQR-----FGSIFNKHKAPQDNDLISGLTKKFNR--------LGST 470
Q P + S + P+ + IS T + +R + T
Sbjct: 430 AQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDT 489
Query: 471 SAENVFMQHVPELTTLLSDLDKNKFPQEGVTLLNQNIDPKTYMP-QDVVILIVGGLTIEE 529
+ + +H P ++T S ++N P Y ++I I+GG+++ E
Sbjct: 490 IEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNE 549
Query: 530 ARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDV 566
R ++ + K V+IG T I++ +FL D+
Sbjct: 550 MRCAYEVTQANGK----WEVLIGSTHILTPTKFLMDL 582
>CE17219 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 562
Score = 89.4 bits (220), Expect = 1e-17
Identities = 105/555 (18%), Positives = 228/555 (40%), Gaps = 53/555 (9%)
Query: 31 RVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQ 90
+ L+LD + ++ C + E+ + + LV+ L +R+PMP + + + P ++I
Sbjct: 28 KFSVLVLDKSAMVVVNSCLSLNEVFEEGVTLVEDLTR-NREPMPSMDAIYIISPVAESID 86
Query: 91 DLLHELQDP-------KYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVN 143
L+++ Y IFF + E+L++ ++ + ++E+ + V
Sbjct: 87 ILINDFSRKTKFNPGNSYRSAHIFFLDPCCDELFEKLSKSPAVKWIKTLKELNLNLKPVE 146
Query: 144 EDVFTLEIPLYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLAKD 203
+FT+ +Q D + +T++G +PT+ + SD ++ +
Sbjct: 147 SQIFTVN--------SQFRGD---MTKTADGIVSLCATLNIHPTLRFQSDFAQSSEICQR 195
Query: 204 LEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRNLVDL 263
+E ++K F ++ L++LDR D ++PLL T Q+M+ + K +
Sbjct: 196 VEQKLKE-----FGNEGMGTDAELVVLDRSFDLVSPLLHEVTLQAMVVDVTAFKDGVYRY 250
Query: 264 SNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNITKQINTXXX 323
+ D K++VL K D+ + + + ++ V V +KN TN T+ N
Sbjct: 251 TEA----GDSKEIVLDEK-DQNWLDLRHKLLPEVMKSVNKMVKDFKN-TNKTEPENIKNQ 304
Query: 324 XXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLK---NIWEVSELEQNLS-SHDDNNDD 379
+ MA L + + K ++ ++ LEQ+++ H +
Sbjct: 305 SSKDFSTTVRTLQPYLKMKAKMAAYISLTEECRSKYFDSLEKIIALEQDMAVEHTPEHVR 364
Query: 380 FVELKRI-----LNLPTLESYYKLKLCCIFVLRHGKNE-----SRVSELENILRQQCDPT 429
+ + + LP + + +L+L IF+L GK++ +R+ +I +
Sbjct: 365 ITDSQAVGRLSTFILPAIPTETRLRLILIFMLTIGKDKDEQYFNRLLHHTDIPESEFQII 424
Query: 430 QISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFMQHVPELT-TLLS 488
+ L ++ K + ++ P+D I+ +++ E ++ + + E +
Sbjct: 425 KRMLIWRDKTQKSQFQHRRPPPEDERFIA---SRWDPKIKNLIEEIYERRLDEREFKVAG 481
Query: 489 DLDKNKFPQEGVTLLNQNIDPKTYMPQDVVILIVGGLTIEEARAVHQFNEKQSKNKDNCR 548
+ F + K + ++I +VGG+T E R ++ ++ K N
Sbjct: 482 KKSTSDFRPAASARYGSGLAGKPREKRKIIIFVVGGITYSEMRVAYELSK-----KTNTT 536
Query: 549 VIIGGTSIISTEQFL 563
VI+G I++ FL
Sbjct: 537 VILGSDEILTPSSFL 551
>SPCC74.01 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 639
Score = 88.2 bits (217), Expect = 3e-17
Identities = 78/365 (21%), Positives = 162/365 (44%), Gaps = 30/365 (8%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
K LI D TIS ++L KH + + + + R P+ + + +++PT++ I+ +
Sbjct: 47 KVLIFDKAGSETISSVLRISDLRKHGVTVHMNITSF-RQPIADVPAIYFVQPTQENIELI 105
Query: 93 LHELQDPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTH----VEEVFQDYLIVNEDVFT 148
+ +L Y + F++ +S++ LE+ AE +H V + + +Y+++ D F+
Sbjct: 106 IEDLSKGLYESAYVCFSSTISRALLEQFAELASKTNTSHMIHQVYDQYLNYVVLESDFFS 165
Query: 149 LEIP-----LYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLAKD 203
L++P +N ++ + + + +Q+ NG P I S + +A+
Sbjct: 166 LQLPKIFHTFHNPSSDEALINSR-VQDIVNGLFSVIVTLGTIPIIRCPQGSA-AEMVAQK 223
Query: 204 LEYEIKT---NERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRNL 260
L +K N + F P+LILLDR D + + WTYQ++I++ + ++ N
Sbjct: 224 LNQRLKDHLMNTKDAFVSVNPKPRPILILLDRTVDLIPMINHSWTYQALIHDTLNMQLNR 283
Query: 261 VDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKN-KTNITKQIN 319
+ + +V + K+ D F++ F +A+ + +T+YKN + IT++
Sbjct: 284 ITVESVDD-GKMTKRFYDLDGNDFFWESNASKPFPKVAENIDEELTRYKNDASEITRKSG 342
Query: 320 TXXXXXXXXXXXXXXXXLSGNIS-------------KHMAIVSELDRQLQLKNIWEVSEL 366
L +S HM I + L + +Q +++ + +L
Sbjct: 343 VSSLEEVNVDAFADSTYLKSAVSLLPELTARKQILDMHMNIATALLKAIQERHLDDFFQL 402
Query: 367 EQNLS 371
E N++
Sbjct: 403 EDNIT 407
>Hs7706371 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 640
Score = 82.8 bits (203), Expect = 1e-15
Identities = 88/362 (24%), Positives = 153/362 (41%), Gaps = 41/362 (11%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
K LI D IS + EL I L L + RDP+P + + ++ PTE+ I +
Sbjct: 42 KVLIYDRFGQDIISPLLSVKELRDMGITL-HLLLHSDRDPIPDVPAVYFVMPTEENIDRM 100
Query: 93 LHELQDPKYGEYQIFFNNQVSKSQLERLAERD-DMEVVTHVEEVFQDYL---IVNEDVFT 148
+L++ Y Y + F + +S+S+LE +A ++ VT V +VF YL + +D+F
Sbjct: 101 CQDLRNQLYESYYLNFISAISRSKLEDIANAALELSAVTQVAKVFDQYLNFITLEDDMFV 160
Query: 149 L-----EIPLYNLLQNQLVWDP--KGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLA 201
L E+ Y + + D + + +T I S + +A
Sbjct: 161 LCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFYGTLGAVPIIRCSRGTAAEMVA 220
Query: 202 KDLEYEIKTNERQL--------------FDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQ 247
L+ +++ N R F F PLL+L+DR D TPL WTYQ
Sbjct: 221 VKLDKKLRENLRDARNSLFTGDTLGAGQFSF----QRPLLVLVDRNIDLATPLHHTWTYQ 276
Query: 248 SMINEYIGIKRNLVDL---SNVPNIDPDLKQVVLSSKQ------DKFFKETMYMNFGDLA 298
+++++ + N V+L S V N + + K DKF+++ F ++A
Sbjct: 277 ALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVA 336
Query: 299 DKVKNYVTQYKNKTNITKQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLK 358
+ V+ + Y+ + + K++ + LS N +K + VS L L+ K
Sbjct: 337 ESVQQELESYRAQEDEVKRLKS--IMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKK 394
Query: 359 NI 360
+
Sbjct: 395 RL 396
>Hs7706407 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 638
Score = 81.3 bits (199), Expect = 4e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 41/362 (11%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
K LI D IS + EL I L L + RDP+P + + ++ PTE+ I +
Sbjct: 41 KVLIYDRFGQDIISPLLSVKELRDMGITL-HLLLHSDRDPIPDVPAVYFVMPTEENIDRM 99
Query: 93 LHELQDPKYGEYQIFFNNQVSKSQLERLAERD-DMEVVTHVEEVFQDYL---IVNEDVFT 148
+L++ Y Y + F + +S+S+LE +A VT V +VF YL + +D+F
Sbjct: 100 CQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFV 159
Query: 149 L-----EIPLYNLLQNQLVWDPK--GLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLA 201
L E+ Y + + D + + +T + I S + +A
Sbjct: 160 LCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFYGTRGDVPIIRCSRGTAAEMVA 219
Query: 202 KDLEYEIKTNERQL--------------FDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQ 247
L+ +++ N R F F PLL+L+DR D TPL WTYQ
Sbjct: 220 VKLDKKLRENLRDARNSLFTGDTLGAGQFSF----QRPLLVLVDRNIDLATPLHHTWTYQ 275
Query: 248 SMINEYIGIKRNLVDL---SNVPNIDPDLKQVVLSSKQ------DKFFKETMYMNFGDLA 298
+++++ + N V+L S V N + + K DKF+++ F ++A
Sbjct: 276 ALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVA 335
Query: 299 DKVKNYVTQYKNKTNITKQINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLK 358
+ V+ + Y+ + + K++ + LS N +K + VS L L+ K
Sbjct: 336 ESVQQELESYRAQEDEVKRLKS--IMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKK 393
Query: 359 NI 360
+
Sbjct: 394 RL 395
>Hs6005886 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 592
Score = 80.1 bits (196), Expect = 8e-15
Identities = 110/583 (18%), Positives = 240/583 (40%), Gaps = 71/583 (12%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
K ++LD T ++ C T+LL+ I +V+ + +R+P+ +K L ++ PT ++
Sbjct: 33 KIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYK-NREPVRQMKALYFITPTSKSVDCF 91
Query: 93 LHEL---QDPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVNEDVFTL 149
LH+ + KY I+F + + ++ + + + +E+ ++ V+TL
Sbjct: 92 LHDFASKSENKYKAAYIYFTDFCPDNLFNKI-KASCSKSIRRCKEINISFIPHESQVYTL 150
Query: 150 EIP-LYNLLQNQLVWDPKG----LQETSNGXXXXXXXXXXNPTIAY-----DSDSKLCQK 199
++P + + + KG ++ ++ NP + Y D+ SKL Q
Sbjct: 151 DVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQL 210
Query: 200 LAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRN 259
+ K LE K +E+ L ++ L+++DR DP++ +L T+Q+M + + I+ +
Sbjct: 211 VEKKLEDYYKIDEKSLIK---GKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIEND 267
Query: 260 LVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNITKQIN 319
D K+ +L ++D + + + + +++ + + + T+
Sbjct: 268 TYKYKT----DGKGKEAIL-EEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKT 322
Query: 320 TXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNNDD 379
+ H+ + + + +L NI ++ + EQ+L+ D
Sbjct: 323 SLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKL-NIEKLCKTEQDLALGTDAEGQ 381
Query: 380 FVELKRILNLPTL-----ESYYKLKLCCIFVLR-HGKNESRVSELENILRQQCDPTQISL 433
V+ + LP L ++ K++ +++ +G E + L ++ + I
Sbjct: 382 KVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIGNESDMI-- 439
Query: 434 YFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFM--QHVPELTTLLSD-- 489
R S PQ G + +R SAE F + P + ++ D
Sbjct: 440 ------RNWSYLGVPIVPQSQ---QGKPLRKDR----SAEETFQLSRWTPFIKDIMEDAI 486
Query: 490 ---LDKNKFPQ--------EGVTLLNQNIDPKTYMPQD------VVILIVGGLTIEEARA 532
LD ++P G ++ P+ +D +++ ++GG+T E R
Sbjct: 487 DNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRG 546
Query: 533 VHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDVCAVNDKPVD 575
++ ++ +C VIIG T +++ ++ L D+ +N KP D
Sbjct: 547 AYEVSQAHK----SCEVIIGSTHVLTPKKLLDDIKMLN-KPKD 584
>At4g12120 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 635
Score = 75.9 bits (185), Expect = 2e-13
Identities = 84/414 (20%), Positives = 179/414 (42%), Gaps = 34/414 (8%)
Query: 13 RIANFQSKPSDTSIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLE-NIHRD 71
R+ +F+ + + +S K K L++D T+ +S +E+ + I + L HR
Sbjct: 14 RVLHFRPERNGSS---KLTWKVLVMDKFTVKIMSSACKMSEITQEGISCKNHLVITKHRQ 70
Query: 72 PMPHLKCLCYLKPTEDTIQDLLHEL--QDPKYGEYQIFFNNQVSKSQLERLAERDDMEVV 129
PM ++ + +++PTE+ + L ++ + P Y + +FF++ VS+S + + + DM +
Sbjct: 71 PMTAMEVIYFIQPTEENVTAFLSDMTGKSPLYKKAFVFFSSPVSRSLVNLI--KKDMRAM 128
Query: 130 THVEEVFQDYLIVNEDVFTLEI----------PLYNLLQNQLVWDPKGLQETSNGXXXXX 179
+ + + ++ NE+ N++ ++ L+E
Sbjct: 129 KRIGGLKEGFVTNNENALEELFCDDENHQRADACLNVVAKRIATVLASLKEYPFVRYRGA 188
Query: 180 XXXXXNPTIAYDSDSKLCQKLAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTP 239
Y + KLA + + ++ + DFP ++ LLIL DR D + P
Sbjct: 189 KALDATTMTTYRE--LIPTKLAASVWNCLARYKQTIEDFPQTETCELLIL-DRSIDQIAP 245
Query: 240 LLQPWTYQSMINEYIGIKRNLV--DLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDL 297
L+ WTY +M ++ + ++ N ++ + P+ K+V+L ++D + E + D
Sbjct: 246 LIHEWTYDAMCHDLLNMEGNKYTHEVPSKTGDKPEKKEVLL-DEEDSIWVELRDAHIADA 304
Query: 298 ADKVKNYVTQY--KNKTNITKQINTXXXXXXXXXXXXXXXXLS------GNISKHMAIVS 349
++++ +T + KNK K + L +S H+ I
Sbjct: 305 SERLHEKMTNFVSKNKAAQLKHSSKDFGDLSSKDLQKMVHALPQYSEQIDKLSLHVEIAR 364
Query: 350 ELDRQLQLKNIWEVSELEQNLSSHDDNNDDFVELKRILNLPTLESYYKLKLCCI 403
++R + + + ++ +LEQ+L D D ++ ++ + ES KL+L I
Sbjct: 365 TINRTIMEQGLRDLGQLEQDLVFGDAGRKDVIKFLSTNHIISHES--KLRLIMI 416
>CE24927 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 591
Score = 72.4 bits (176), Expect = 2e-12
Identities = 126/591 (21%), Positives = 241/591 (40%), Gaps = 67/591 (11%)
Query: 29 KSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDT 88
+S LI+D + +S C +++ I +V+ L N R+P+P L+ + + PT ++
Sbjct: 25 RSAWNVLIVDTLAMRMLSSCCKMHNIMEEGITIVEDL-NKRREPLPTLEAIYLIAPTAES 83
Query: 89 IQDLLHELQDPK-YGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVNEDVF 147
I L+ + Y +FF S L++ + ++E+ + VF
Sbjct: 84 IDKLIQDYCARNLYKCAHVFFTEACSDQLFSTLSKSAAARFIKTLKEINIAFTPYESQVF 143
Query: 148 TLEIP----LYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLAKD 203
L+ P LY Q Q L+ + P++ Y +D + +L
Sbjct: 144 NLDSPDTFFLYYNAQKQGGLT-SNLERIAEQIATVCATLGEYPSLRYRADFERNVELGHL 202
Query: 204 LEYEI---KTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRNL 260
+E ++ K ++ + + + + LI++DR D +TPLL T Q+M + +GI+ N
Sbjct: 203 VEQKLDAYKADDPSMGEGADK-ARSQLIIIDRGYDAITPLLHELTLQAMCYDLLGIE-ND 260
Query: 261 VDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKV-KNYVTQYKNKTNI-TKQI 318
V D +L++ VL + D + E + + ++ +V KN ++K N T
Sbjct: 261 VYKYETGGSDENLEKEVLLDENDDLWVEMRHKHIAVVSQEVTKNLKKFSESKGNKGTMDS 320
Query: 319 NTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNND 378
+ S H+++ E +Q Q + + ++ ++EQ+LS+ D
Sbjct: 321 KSIKDLSMLIKRMPQHKKELNKFSTHISLAEECMKQYQ-QGVDKLCKVEQDLSTGIDAEG 379
Query: 379 DFVE--LKRILNL---PTLESYYKLKLCCIFVL-RHGKNESRVSEL---ENILRQQCDPT 429
+ V +K ++ L P + +L+L +++L ++G + +++L NI +
Sbjct: 380 ERVRDAMKLMVPLLIDPAVRCEDRLRLILLYILSKNGITDENLNKLLQHANISMADKETI 439
Query: 430 QISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFM--QHVPELTTLL 487
+ Y + K P TKK E V+ + VP + ++
Sbjct: 440 TNAAYLGLNIVTDTGRKKTWTP---------TKK-----ERPHEQVYQSSRWVPVIKDII 485
Query: 488 SD-----LDKNKFPQEGVTLLNQNI----------------DPKTYMP-QDVVILIVGGL 525
D LD FP +NQ Y ++I I+GG+
Sbjct: 486 EDAIDERLDTKHFPFLAGRQVNQGYRAPASARYGQWHKERGQQSNYRSGPRLIIYIIGGV 545
Query: 526 TIEEARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDVCAVNDKPVDL 576
T E RA ++ + V+IG II+ ++FLT++ +N KP D+
Sbjct: 546 TFSEMRACYEVTAARKP----WEVVIGSDRIITPDKFLTNLRDLN-KPRDI 591
>At1g12360 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 637
Score = 70.5 bits (171), Expect = 7e-12
Identities = 93/514 (18%), Positives = 206/514 (39%), Gaps = 50/514 (9%)
Query: 29 KSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDT 88
KS K LI+D T+ +S ++ + + LV+ + R P+P + + +++PT++
Sbjct: 11 KSTWKVLIMDKLTVKIMSYACKMADITQEGVSLVEDIFR-RRQPLPSMDAIYFIQPTKEN 69
Query: 89 IQDLLHEL--QDPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVNEDV 146
+ L ++ + P Y + +FF++ VSK + + + D V+ + + + +N +
Sbjct: 70 VIMFLSDMSGKSPLYKKAFVFFSSPVSKELVGHI--KKDSSVLPRIGALRE----MNLEF 123
Query: 147 FTLEIPLYNLLQNQLVWDPKGLQETS-----------NGXXXXXXXXXXNPTIAYDSDSK 195
F ++ + + + D G +ETS + P + Y +
Sbjct: 124 FAIDSQGFITDHERALEDLFGDEETSRKGDACLNVMASRIATVFASLREFPAVRYRAAKS 183
Query: 196 L------------CQKLAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQP 243
L KLA + + +++ + +FP ++ LLI LDR D + P++
Sbjct: 184 LDASTMTTLRDLIPTKLAAGIWNCLAKHKQSIENFPQTETCELLI-LDRSIDQIAPVIHE 242
Query: 244 WTYQSMINEYIGIKRN--LVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKV 301
WTY +M ++ + ++ N + + + P+ K V+L + D + E + + D ++++
Sbjct: 243 WTYDAMCHDLLNMEGNKYVHVIPSKSGGQPEKKDVLL-EEHDPIWLELRHAHIADASERL 301
Query: 302 KNYVTQYKNKTNITK--------QINTXXXXXXXXXXXXXXXXLSGNISKHMAIVSELDR 353
+ +T + +K + +++T + +S H+ I +L+
Sbjct: 302 HDKMTNFLSKNKAAQLQGKRDGAELSTRDLQKMVQALPQYSEQID-KLSLHVEIARKLND 360
Query: 354 QLQLKNIWEVSELEQNLSSHDDNNDDFVELKRILNLPTLESYYKLKLCCIFVLRHGKNES 413
++ + + E+ +LEQ+L D D ++ + E +L + +
Sbjct: 361 LIREQGLRELGQLEQDLVFGDAGMKDVIKYLSTQEEASREGKLRLLMILATIYPEKFEGE 420
Query: 414 RVSELENILRQQCDPTQISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAE 473
+ L + + D ++ ++ K P L L KK + E
Sbjct: 421 KGQNLMKLAKLSSD--DMTAVNNMSLLGSAVDAKKNTPGGFTLKFDLHKKKRAVRKERQE 478
Query: 474 NVFMQ---HVPELTTLLSDLDKNKFPQEGVTLLN 504
Q P + L+ L K + P+E +N
Sbjct: 479 EAAWQLSRFYPMIEELIEKLSKGELPKEDFPCMN 512
>7295949 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 641
Score = 69.7 bits (169), Expect = 1e-11
Identities = 125/621 (20%), Positives = 234/621 (37%), Gaps = 93/621 (14%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
K LI D IS + EL + + L +L + RD +P + + + PT++ + +
Sbjct: 19 KILIYDRVGQDIISPIISIKELRELGVTLHVQLHS-DRDSIPDVPAIYFCLPTDENLDRI 77
Query: 93 LHELQDPKYGEYQIFFNNQVSKSQLERLAERD-DMEVVTHVEEVFQDY---LIVNEDVFT 148
+ Y Y + F +++S++E LA V ++ V+ Y + + +D F
Sbjct: 78 QQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFI 137
Query: 149 LEIPLYNLLQ-------NQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLA 201
L+ + L N + + L ++ N I + + +A
Sbjct: 138 LKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVA 197
Query: 202 KDLEYEIKTN----ERQLFDFPVRDSN--------PLLILLDRKSDPLTPLLQPWTYQSM 249
+ LE +++ N LF + P+L+LLDR D TPL W+YQ++
Sbjct: 198 RKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQAL 257
Query: 250 INEYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYK 309
+++ + + NLV + + + + D+F+ F +A+ ++ + Y+
Sbjct: 258 VHDVLDLGLNLVYVEDETARARKKPKACDLDRNDRFWMTHKGSPFPTVAEAIQEELESYR 317
Query: 310 NKTNITKQINTX-----XXXXXXXXXXXXXXXLSGNISK-------------HMAIVSEL 351
N K++ T L+ ++ H I + +
Sbjct: 318 NSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAI 377
Query: 352 DRQLQLKNIWEVSELEQNLSSHDDNNDDFVELKRILNLPTLESYYKLKLCCI-FVLRHGK 410
++ + + E+E+ + S + ++L R E KL+L I F+
Sbjct: 378 LNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAED--KLRLYIIYFICAQQL 435
Query: 411 NESRVSELENILRQQ-CDPTQISLYFQFKQRFGSIFNKHKA-PQDNDLISGLTK---KFN 465
ES L+ L+ CD T ++ + QR+ I N+ + Q G TK F
Sbjct: 436 PESEQERLKEALQAAGCDLTALA----YVQRWKGIMNRSPSISQATQYEGGGTKTVSMFT 491
Query: 466 RLGSTSAENVFMQHVPELT------------------TLLSDLDKNKFPQEGV------- 500
+L S + V M+ V L L +L K ++ +
Sbjct: 492 KLVSQGSSFV-MEGVKNLVVKRHVSFSFQIQIQVLYQNCLQNLPVTKITEQVMECRSNAE 550
Query: 501 ----------TLLNQNIDPKTYMP-QDVVILIVGGLT-IEEARAVHQFNEKQSKNKDNCR 548
L + PK P QD V+ +VGG IE V +KQ+ N R
Sbjct: 551 TDDYLYLDPKLLKGGEVLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQR-R 609
Query: 549 VIIGGTSIISTEQFLTDVCAV 569
+I G +++ + QFL ++ A+
Sbjct: 610 IIYGASTLTNARQFLKELSAL 630
>7292440 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 597
Score = 68.6 bits (166), Expect = 3e-11
Identities = 110/573 (19%), Positives = 234/573 (40%), Gaps = 61/573 (10%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
+ L++D + +S CT E+ I LV+ + N R+P+P + + + P++++++ L
Sbjct: 40 RVLVVDKLGMRMVSACTKMHEISAEGITLVEDI-NKKREPLPTMDAIYLITPSDESVRGL 98
Query: 93 LHELQDPKYGEYQ---IFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVNEDVFTL 149
+ + ++P Y+ +FF + L + + ++E+ +L VF+L
Sbjct: 99 IRDFENPARPMYRYAHVFFTEVCPEELFNDLCKSCAAGKIKTLKEINIAFLPYECQVFSL 158
Query: 150 EIPLYNLLQNQLVWDP-------KGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLAK 202
+ P Q ++ P K ++ + P + Y SD LA
Sbjct: 159 DSPD----TFQCLYSPAFASIRSKHIERIAEQIATLCATLGEYPNVRYRSDWDRNIDLAA 214
Query: 203 DLEYEI---KTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRN 259
++ ++ K ++ + + P + + LLIL DR D ++PLL T Q+M + + I +
Sbjct: 215 SVQQKLDAYKADDATMGEGPEKARSQLLIL-DRGFDCVSPLLHELTLQAMAYDLLPIVND 273
Query: 260 LVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNITKQIN 319
+ + PN PD + VL + D + E + + V VTQ K +K++
Sbjct: 274 VYRYTPGPN-QPD--KEVLLDENDDLWVELRHEHIA----VVSTQVTQNLKKFTDSKRMG 326
Query: 320 TXXXXXXXXXXXXXXXXLS-----GNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHD 374
+ S H+ + + + Q + ++ +EQ+L+
Sbjct: 327 SADKSSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQ-NYVDKLCRVEQDLAMGT 385
Query: 375 DN-----NDDFVELKRILNLPTLESYYKLKLCCIFV-LRHGKNESRVSELENILRQQCDP 428
D D + IL + +Y K+++ ++V +++G +E +++L Q P
Sbjct: 386 DAEGEKIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKL--FTHAQLSP 443
Query: 429 TQ-----------ISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAEN-VF 476
I++ +++ S+ K + + +S T + E+ +
Sbjct: 444 KDQDMVRNLSCLGINVIADSRKKQYSVPRKERTTESTYQMSRWTPVIKDIMEDCIEDKLD 503
Query: 477 MQHVPELTTLLSDLDKNKFPQEGVTLLNQNIDPKTYMPQDV---VILIVGGLTIEEARAV 533
++H P L + N + + D ++V ++ IVGG+++ E R
Sbjct: 504 LRHFPFLEGRAQ--NTNYHAPTSARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEMRCA 561
Query: 534 HQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDV 566
++ N V++G + I+S E FL+D+
Sbjct: 562 YEVTNAVR----NWEVLVGSSHILSPEIFLSDL 590
>At1g02010 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 426
Score = 67.0 bits (162), Expect = 7e-11
Identities = 74/405 (18%), Positives = 160/405 (39%), Gaps = 56/405 (13%)
Query: 217 DFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRN--LVDLSNVPNIDPDLK 274
+FP ++ LLI+ DR D + P++ WTY +M ++ + ++ N ++++ + P+ K
Sbjct: 18 NFPQTETCELLIV-DRSVDQIAPIIHEWTYDAMCHDLLDMEGNKHVIEVPSKTGGPPEKK 76
Query: 275 QVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNITKQINTXXXXXXXXXXXXXX 334
++VL D + E + + D ++++ +T + +K + +
Sbjct: 77 EIVLED-HDPVWLELRHTHIADASERLHEKMTNFASKNKAAQMRSRDGSELSTRDLQKIV 135
Query: 335 XXLS------GNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNNDDFVELKRILN 388
L +S H+ + +++R ++ + ++ +LEQ+L D D + R
Sbjct: 136 QALPQYGEQVDKLSTHVELAGKINRIIRDTGLRDLGQLEQDLVFGDAGAKDVINFLRTNQ 195
Query: 389 LPTLESYYKLKLCCIFVLRHGKNESRVSELENILRQQCDPTQISLYFQFKQRFGSIFNKH 448
E+ KL+L I+ + + ++ + + P + + + GS NK
Sbjct: 196 DTNPEN--KLRLLMIYATVYPEKFEGDKGVKLMQLARLSPVDMKVISNMQLIAGSPENKA 253
Query: 449 KAPQDN-DLISGLTKKFNRLGSTSAENVF--MQHVPELTTLLSDLDKNKFPQEGVTLLNQ 505
K+ + +G TK+ NR + E + + P + LL L K + +NQ
Sbjct: 254 KSGSFSLKFDAGKTKQANRKDRSGEEETWQLFRFYPMIEELLEKLVKGDLSKSDYLCMNQ 313
Query: 506 NIDPKT--------------------YMPQD----------------VVILIVGGLTIEE 529
+ + + P D + + I+GG T E
Sbjct: 314 SSHKEESEARTGSVRKSSAPTAFISFFTPSDSVLKSASTEFKKLGQRIFVFIIGGATRSE 373
Query: 530 ARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFLTDVCAVNDKPV 574
R H+ + V++G TS Q++T + +++K +
Sbjct: 374 LRVCHKLTSSLRR-----EVVLGSTSFDDPPQYITKLKLLSEKDI 413
>ECU03g0900 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 521
Score = 63.9 bits (154), Expect = 6e-10
Identities = 73/359 (20%), Positives = 151/359 (41%), Gaps = 36/359 (10%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
K L+LD+ T I +EL + I L R P+ + + +++ + + D+
Sbjct: 22 KILVLDSRTQQIIGPLMKVSELRECGI-TAHFLVTQERHPISNTPAVYFVESADGVLDDV 80
Query: 93 LHELQDPKYGEYQIFFNNQVSKSQLERL----AERDDMEVVTHVEEVFQDYLIVNEDVFT 148
L EL Y EY + F V++ ++E L +ER + V + F D++ + +D+FT
Sbjct: 81 LAEL----YSEYYLNFATSVTRGEIESLGLGLSERGLGLRIRSVYDQFVDFIALQDDMFT 136
Query: 149 LEIP-LYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIAYDSDSKLCQKLAKDLEYE 207
L + + ++N W + S +D + ++A+ LE +
Sbjct: 137 LGMKGSFIEMENPDTWRRMVMSVMS------VFVTLGEVPFIVATDDDVTTQMARMLETK 190
Query: 208 IKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMINEYIGIKRNLVDLSNVP 267
I R P+L+L+ R D +TP+ W+Y +++N+ ++ N + L +
Sbjct: 191 I----RNTGVIKRGSKRPVLVLVSRSHDVITPVQHVWSYSALMNDLFALESNKITLKSGK 246
Query: 268 NIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKNKTNITKQINTXXXXXXX 327
D D QD+ ++ F + ++V+ + +YK K + I+
Sbjct: 247 VFDLD--------PQDELWRRNANEYFPVVVERVEKELLEYK-KEMALRSIDEKTDKKVI 297
Query: 328 XXXXXXXXXL---SGNISKHMAIVSELDRQLQLKNIWEVSELEQNLSSHDDNNDDFVEL 383
L + +++ H++I SE+ ++ + I + ++E+ N + +EL
Sbjct: 298 QEALDKAPELAKRNESVNAHISICSEMVEMIKERAIDDFYKVEKG----GHTNQELIEL 352
>SPCC584.05 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 693
Score = 60.1 bits (144), Expect = 9e-09
Identities = 110/585 (18%), Positives = 221/585 (36%), Gaps = 62/585 (10%)
Query: 25 SIQEKSRVKALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKP 84
S++ ++ K LI+D T I+ T LL+ +I V+ LEN R P + L L
Sbjct: 17 SVECATKWKVLIVDTKTADIINHFITIHSLLEEKIAAVEILEN-PRTPNSSFEALYILHS 75
Query: 85 TEDTIQDLLHELQ-DPKYGEYQIFFNNQVSKSQLERLAERDDMEVVTHVEEVFQDYLIVN 143
E + +L + + D +Y I F + V + + +L + V+ + D+ +
Sbjct: 76 EEKLVDCILKDEEYDKRYPGIHIVFLDMVKEPLINKLRTSRIASKIRTVQVAYLDFTSLE 135
Query: 144 EDVFTLE-----IPLYNLLQNQLVWDPKGLQETSNGXXXXXXXXXXNPTIA--YDSDSKL 196
F + + LY+ ++ + L + ++G +P I Y ++
Sbjct: 136 SRYFQVHDSFSGLRLYHPSNAAII--RQELSKVAHGIFSVCVSLGISPNIRCYYPKNAPH 193
Query: 197 CQK-----LAKDLEYEIKTNERQLFDFPVRDSNPLLILLDRKSDPLTPLLQPWTYQSMIN 251
K LA L ++ + + S +++DR D P L +TYQ+MI+
Sbjct: 194 ASKTMSFILANQLSEIVEEYCSKHPGYHEAASKSTCLIVDRSLDTAAPFLHEFTYQAMIH 253
Query: 252 EYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQY--K 309
+ + IK + K+ D + +M+ D +K+ Q+
Sbjct: 254 DLLPIKNEQYPY-EILGPQGTEKRTGKLDDDDLVYTTIRHMHMRDAIEKLMKDFNQFCID 312
Query: 310 NKTNITKQINTX-XXXXXXXXXXXXXXXLSGNISKHMAIVSELDRQLQLKNIWEVSELEQ 368
N + K+ T L S H+ + E + + + + +EQ
Sbjct: 313 NTLFLDKERATSLNDMRSMLAGLSDFQELRDQYSLHLTMAQECMNIFEKQQLNLIGAIEQ 372
Query: 369 NLSSHDD-----NNDDFVELKRILNLPTLESYYKLKLCCIFVLRHGKNESRVSELENILR 423
+LS+ + EL +L+ E K++L ++++ ++ + +L + R
Sbjct: 373 DLSTGSNVEGKVPRSVLSELLPLLDEGNAEESTKIRLLLLYIIY--RDGIILQDLFRLFR 430
Query: 424 QQCDPTQISLYFQFKQRFGSIFNKHKAPQDNDLISGLTKKFNRLGSTSAENVFMQHVPEL 483
T FQ ++ G+ K+ Q S + N L + ++VP L
Sbjct: 431 HSNLSTSREQIFQNLEQLGTRVIKNLTDQS----SKRKEVANSLPAGEDVYELSRYVPTL 486
Query: 484 TTLLSDLDKNKFPQEGVTLLNQNIDPKTYMPQD-------------------------VV 518
+L +L ++K E + +N P+T + + ++
Sbjct: 487 KVVLENLIQDKLDPELFPYV-RNTTPQTEVSMEQTSLRSSRPSWTRSRSMASKLPREKML 545
Query: 519 ILIVGGLTIEEARAVHQFNEKQSKNKDNCRVIIGGTSIISTEQFL 563
+ + GG T E R ++ ++K +K+ + IG T S ++L
Sbjct: 546 VFVAGGTTFSELRTCYELSDKYNKD-----IYIGSTVCYSPNEWL 585
>At2g17980 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 627
Score = 59.3 bits (142), Expect = 2e-08
Identities = 64/307 (20%), Positives = 135/307 (43%), Gaps = 29/307 (9%)
Query: 21 PSDTSIQEKSRVKALILDNDTLSTISMCTTQTELLKHEI---YLVDKLENIHRDPMPHLK 77
PS T+ +E ++ LI D + +S T +L KH + +L+DK R P+ +
Sbjct: 25 PSGTANEEVYKI--LIYDRFCQNILSPLTHVKDLRKHGVTLFFLIDK----DRQPVHDVP 78
Query: 78 CLCYLKPTEDTIQDLLHELQDPKYGEYQIFFNNQVSKSQLERLA----ERDDMEVVTHVE 133
+ +++PTE +Q ++ + Y + + F++ + + LE LA + +E V+ V
Sbjct: 79 AVYFVQPTESNLQRIIADASRSLYDTFHLNFSSSIPRKFLEELASGTLKSGSVEKVSKVH 138
Query: 134 EVFQDYLIVNEDVFTLEIPLYNLLQNQLVWDPKGLQE----TSNGXXXXXXXXXXNPTIA 189
+ + +++ + +++F+L + N K + E ++G P I
Sbjct: 139 DQYLEFVTLEDNLFSLAQQSTYVQMNDPSAGEKEINEIIERVASGLFCVLVTLGVVPVIR 198
Query: 190 YDSDSKLCQKLAKDLEYEIK---TNERQLF----DFPVRDSNPLLILLDRKSDPLTPLLQ 242
S + +A L+ +++ ++ LF F PLL + DR + +
Sbjct: 199 CPSGGP-AEMVASLLDQKLRDHLLSKNNLFTEGGGFMSSFQRPLLCIFDRNFELSVGIQH 257
Query: 243 PWTYQSMINEYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVK 302
+ Y+ ++++ +G+K N + V K L S D F+ + F D+A +++
Sbjct: 258 DFRYRPLVHDVLGLKLNQL---KVQGEKGPPKSFELDS-SDPFWSANSTLEFPDVAVEIE 313
Query: 303 NYVTQYK 309
+ +YK
Sbjct: 314 TQLNKYK 320
>CE00993 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 707
Score = 58.9 bits (141), Expect = 2e-08
Identities = 64/308 (20%), Positives = 129/308 (41%), Gaps = 24/308 (7%)
Query: 33 KALILDNDTLSTISMCTTQTELLKHEIYLVDKLENIHRDPMPHLKCLCYLKPTEDTIQDL 92
K L+LD IS +L + + L L R+P+ + + ++ P ++ I +
Sbjct: 65 KVLVLDRTGQDIISPLLPVKQLRELGVTL-HLLIGARREPLTDVPAVYFVSPNDENIDLM 123
Query: 93 LHELQDPKYGEYQIFFNNQVSKSQLERLAERD-DMEVVTHVEEVFQDYL---IVNEDVFT 148
+L+ Y + F + +++ +LE LA V+ V++V YL + +D+F
Sbjct: 124 SEDLKKAMYDSFYCNFISPLARPRLESLASAAVHGGAVSQVQKVVDQYLNFISLEDDLFV 183
Query: 149 LEIPLYNLLQNQLVWDPKG---------LQETSNGXXXXXXXXXXNPTIAY---DSDSKL 196
L N + + G L ++G P I ++ +
Sbjct: 184 LRRYSENSTFSYHAMNSPGTSDVAVNAMLDSIADGLFAVCATMGIVPIIRCPKGNAAEMV 243
Query: 197 CQKLAKDLEYEIKTNERQLFDFP------VRDSNPLLILLDRKSDPLTPLLQPWTYQSMI 250
+KL + L ++ + LF ++ S PLL++ DR +D T L WTYQ+++
Sbjct: 244 AKKLDQKLRDNLRDSRNNLFTMDGVRMGLLQTSRPLLVIGDRSADLATMLHHTWTYQALM 303
Query: 251 NEYIGIKRNLVDLSNVPNIDPDLKQVVLSSKQDKFFKETMYMNFGDLADKVKNYVTQYKN 310
++ + + +N V +S + + + DK + F +A+ V+ + Y++
Sbjct: 304 HDVLELDQNRVTIS-TSSTGKKKDYDMATGGSDKLWNNHKGSAFPTVAEAVQENLDDYRS 362
Query: 311 KTNITKQI 318
K + K+I
Sbjct: 363 KEDDIKKI 370
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,425,995
Number of Sequences: 60738
Number of extensions: 1431436
Number of successful extensions: 3969
Number of sequences better than 1.0e-05: 25
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3893
Number of HSP's gapped (non-prelim): 36
length of query: 577
length of database: 30,389,216
effective HSP length: 112
effective length of query: 465
effective length of database: 23,586,560
effective search space: 10967750400
effective search space used: 10967750400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)