ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4902 good L KOG1275 Replication, recombination and repair PAB-dependent poly(A) ribonuclease, subunit PAN2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4902 1680310 1676879 -1144
(1144 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL094c [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 1063 0.0
SPAC22G7.04 [L] KOG1275 PAB-dependent poly(A) ribonuclease subun... 414 e-115
Hs7662258 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit... 299 2e-80
7303975 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 209 2e-53
CE01269 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 125 3e-28
At3g15080 [L] KOG2249 3'-5' exonuclease 70 2e-11
Hs13569960 [L] KOG2249 3'-5' exonuclease 69 6e-11
7294419 [L] KOG2249 3'-5' exonuclease 68 7e-11
Hs21362094 [L] KOG2249 3'-5' exonuclease 67 2e-10
Hs22057667 [L] KOG2249 3'-5' exonuclease 66 3e-10
HsM12232443 [L] KOG2249 3'-5' exonuclease 64 1e-09
Hs13569913 [L] KOG2248 3'-5' exonuclease 64 1e-09
YOL080c [L] KOG2249 3'-5' exonuclease 59 6e-08
Hs9966857_2 [L] KOG2249 3'-5' exonuclease 56 3e-07
YGR276c [L] KOG2248 3'-5' exonuclease 56 4e-07
YLR107w [L] KOG2248 3'-5' exonuclease 54 1e-06
>YGL094c [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1115
Score = 1063 bits (2748), Expect = 0.0
Identities = 556/1151 (48%), Positives = 759/1151 (65%), Gaps = 47/1151 (4%)
Query: 1 MNNWQLSYQSPEDLTYHLKKPYLQYDKKEKQVTKVVFDTEANLIWAGDSYGRVSSYDPTY 60
MNNWQ + +P DL+ HLKKPY ++D ++K++T + FD +ANLIW+GDSYG +SSYDPT+
Sbjct: 1 MNNWQHFFNNPVDLSEHLKKPYFRFDNRDKEITAISFDEKANLIWSGDSYGCISSYDPTF 60
Query: 61 SLYTRHTAHIGSMPVVDLLSNKNGILSLSSDSLHFSNRRGVTQMSLTSADIAQLSDMKTM 120
LYTR+ HIG V D+LS+++GILS+S DSLHF+NRRGVT+++LTS DIA S++ TM
Sbjct: 61 QLYTRYRGHIGGNSVKDILSHRDGILSISEDSLHFANRRGVTKLNLTSIDIAAFSELNTM 120
Query: 121 CYYTNN-QNQVLCAGGNTASGIISVDLIKGTLASSTYFTSKVKHMSSNNKLVAIGKQAGS 179
CY ++ +N + C G NT GI S+DL +G L S ++SKVK M SNNK+++IG+Q G+
Sbjct: 121 CYSPHSLKNNIYCGGDNTNWGIASIDLNRGCLDSLLNYSSKVKLMCSNNKVLSIGRQTGT 180
Query: 180 IDLFDPVSNRVIHSLSGHSASITSMDFKDNTLVTAGKSKTFGYLQSDQFINVYDVRIMKQ 239
+DL DP SNR I S + HSASI++MD +DNTLVT GKSK F L +D F+NVYD+R M+Q
Sbjct: 181 VDLLDPTSNRTIKSFNAHSASISAMDLRDNTLVTVGKSKRFYNLYADPFVNVYDLRTMRQ 240
Query: 240 LPPISFSKTPNFVGNHTSSKFPIGADFLQLHPVLPTVVAVASSSGSFDFIDLVNPSLRTP 299
LPP+SFSK GADF+QLHP+LPTV+ VASSSGSFDFIDL NP+LRT
Sbjct: 241 LPPVSFSKGTTMGSG--------GADFVQLHPLLPTVMIVASSSGSFDFIDLSNPTLRTQ 292
Query: 300 YIHPCKSISQFTLSPSGDYLAFLEEESMINMWNRS-NSMSGFTNSAAVLEYQDYPEDSFI 358
Y+HPC+SI + LSP+GD L LE ++ ++ W RS N+M FTN+ +L Y DY D
Sbjct: 293 YVHPCQSIKKLCLSPNGDVLGILEADNHLDTWRRSSNNMGMFTNTPEMLAYPDYFNDITS 352
Query: 359 PYRVEVGQESYPLSSIGLPYYSETLLSAWPHTVFKTXXXXXXXXXXXXXXXTDNNSTKXX 418
+ V E+YPLSS+G+PYY + LLSAWP VFK+ + +
Sbjct: 353 DGPISVDDETYPLSSVGMPYYLDKLLSAWPPVVFKSEGTIPQLTGKSPLPSSGKLKSNLA 412
Query: 419 XXXXXXXXXXXXXXQ--PYNKFKYGPRNVIEPYKSLRERRKKMVSTTEDNQHRKELLEYK 476
Y++ KYG RN I Y LR+ RK++ S E + ++ Y
Sbjct: 413 VISSQNEKLSTQEFPLLRYDRTKYGMRNAIPDYVCLRDIRKQITSGLETS----DIQTYT 468
Query: 477 PSNNIDIPPAYSKLQMIYGKFGVMDFDFGGFNTTQYSGLETDIDCVYINEIIHLYRFVPE 536
N ++PPAYS+L + G+FG +FDF FN T+YSGL+ D+D Y N II LYRF+PE
Sbjct: 469 SINKYEVPPAYSRLPLTSGRFGTDNFDFTPFNNTEYSGLDPDVDNHYTNAIIQLYRFIPE 528
Query: 537 VYNFVVNCLEDEHIQEKSVLTELGFLFDMMTRANGKICRASNFVDVLESISTANELGLFT 596
++NFVV CL+DE+ E ++LT+LG+LFDMM R++GKIC +SNF L+S++ +L
Sbjct: 529 MFNFVVGCLKDENF-ETTLLTDLGYLFDMMERSHGKICSSSNFQASLKSLTDKRQL---- 583
Query: 597 DEISTVSGHAGKPSLDEGNLSSHIYNLNLSV---DADAEEIMKRSYGKYMTVAQKFNIFL 653
G+P + +L ++ +L + D ++ E +KR+ + QKFN FL
Sbjct: 584 --------ENGEP---QEHLEEYLESLCIRESIEDFNSSESIKRN------MPQKFNRFL 626
Query: 654 LDRLISEEVERKLHSTDAIVLEELFGLNVDTEIHTLSTCGNFVRQPHXXXXXXXXXPASN 713
L +LI EE + H+ I L + FGL +TEI T +C ++
Sbjct: 627 LSQLIKEEAQTVNHN---ITLNQCFGL--ETEIRTECSCDHYDTTVKLLPSLSISGINKT 681
Query: 714 NVKYSNKKLSNQTILPYIESSMCRFKQLTARCSKCEKLQNQEYESIVRNLPPLLSLNICL 773
+K NKK + Q ILPYIE +M Q + C C K + E V+NLP +LSL + L
Sbjct: 682 VIKQLNKKSNGQNILPYIEYAMKNVTQKNSICPTCGKTETITQECTVKNLPSVLSLELSL 741
Query: 774 SPEEWTTAKTVNGWLSNHFFATISKDRPILKLQATDLKTSNAIFKYELMSYVARITDDFG 833
E++ ++ WL++ F+ +I K++ +L+ A++LK ++ IFKYEL YVA+ITD+
Sbjct: 742 LDTEFSNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKITDNNN 801
Query: 834 EEHLVTYAKILDQKIQQYKWYMFNDFLVQEIDEDEALNISYWWKTPEIVVYSDAEEIRKP 893
E LVTY K + K +KW MFND+LV EI E+EAL ++Y WKTPEI++Y DAEE+RKP
Sbjct: 802 ETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKTPEIIIYCDAEELRKP 861
Query: 894 FVSVSKLKVDTDILYRDYFSEGIRKDVIRQYRLLTKDEAPGPGTLVALDAEFVSLTEPYL 953
F SV ++ DIL+RDYF+ GIR R+Y+LLT DEAP GTLVA+DAEFVSL
Sbjct: 862 FFSVDTYSINYDILFRDYFANGIRDTARREYKLLTHDEAPKSGTLVAIDAEFVSLQSELC 921
Query: 954 EINCKGMKTLLKPAKKSLARVSLLRG-EGELEGVPFIDDYIINECHIEDYLTQFSGIEPG 1012
EI+ +G++++++P + +LAR+S++RG EGEL GVPF+DDY++N HIEDYLT++SGI PG
Sbjct: 922 EIDHQGIRSIIRPKRTALARISIIRGEEGELYGVPFVDDYVVNTNHIEDYLTRYSGILPG 981
Query: 1013 DLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLYYL 1072
DLDP+ S K LV+R V YRK+WLL+QLGCVFVGHGL NDF+ INI VP +QIRDT++Y+L
Sbjct: 982 DLDPEKSTKRLVRRNVVYRKVWLLMQLGCVFVGHGLNNDFKHININVPRNQIRDTAIYFL 1041
Query: 1073 KGKRYLSLRYLAFAVLRKQVQTGNHDSIEDAHTAXXXXXXXXXXXXXGVFEMYLENIYDE 1132
+GKRYLSLRYLA+ +L +Q GNHDSIEDAHTA +FE L ++Y+E
Sbjct: 1042 QGKRYLSLRYLAYVLLGMNIQEGNHDSIEDAHTALILYKKYLHLKEKAIFEKVLNSVYEE 1101
Query: 1133 GRKFGFKVPDT 1143
GR FKVP+T
Sbjct: 1102 GRAHNFKVPET 1112
>SPAC22G7.04 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1115
Score = 414 bits (1064), Expect = e-115
Identities = 330/1154 (28%), Positives = 521/1154 (44%), Gaps = 127/1154 (11%)
Query: 32 VTKVVFDTEANLIWAGDSYGRV-SSYDPTYSLYTRHTAHIGSMPVVDLLSNKNGILSLSS 90
++ + FD + L+W G G++ SS+ P+ + YT+ H G PV +L + G+ SLSS
Sbjct: 21 LSSIAFDPYSELVWTGHKNGQIKSSFGPSLTSYTQFIGHEG--PVHQVLPQERGVFSLSS 78
Query: 91 DSLHFSNRRGVTQMSLTSADIAQLS------------------------DMKTMCYYTNN 126
SL SNR+G + S Q S D + M Y + N
Sbjct: 79 KSLRLSNRKGTIRWRYHSVPCVQRSMIILYSCFLCSKHAVLISRDSDCIDYRAMFYQSRN 138
Query: 127 QNQVLCAGGNTASGIISVDLIKGTLASSTYFTSKVKHMSSNNKLVAIGKQAGSIDLFDPV 186
+V+ G + +++ + +G S + M N+L+ G G I L DP
Sbjct: 139 NPEVVIGGYHQKLTVVNAE--RGISIHKDKNVSDIFIMR-RNRLLCCGSTNGEIILRDPN 195
Query: 187 SNRVIHSLSGHSASITSMDFKDNTLVTAGKSKTFGYLQSDQFINVYDVRIMKQLPPISFS 246
S + ++ + H+ +I+ +D N L++ G S G D F+ V+D+R + L PI F
Sbjct: 196 SFQPVNKVVAHTGTISDIDTSGNLLLSCGYSLRHGTYMLDPFVKVWDLRNLSSLVPIPF- 254
Query: 247 KTPNFVGNHTSSKFPIGADFLQLHPVLPTVVAVASSSGSFDFIDLVNP-SLRTPYIHPCK 305
P G +++HP L T V S SG F +D NP + I
Sbjct: 255 --------------PAGPTIIRMHPKLSTTAVVCSCSGQFHIVDTGNPLDAKLMQIPLTS 300
Query: 306 SISQFTLSPSGDYLAFLEEESMINMWNRSNSMSGFTNSAAVLEYQDYPEDSFIPYRVEVG 365
++ ++ +GD + F + E I++W+ + S F++ ++ P S ++E
Sbjct: 301 YLTGMDIASTGDAMVFTDVEDNIHLWSPLENPS-FSDLKLPIQL---PNTSTETVQLE-- 354
Query: 366 QESYPLSSIGLPYYSETLLSAWP-HTVFKTXXXXXXXXXXXXXXXTDNNSTKXXXXXXXX 424
+ PL+SIGLPYY + LLS+W + +F ++N+
Sbjct: 355 -NNDPLNSIGLPYYKDELLSSWSKYLIFDVGKPILDSNLLIAKQISENSHPVPQEIKSFH 413
Query: 425 XXXXXXXXQPYNKFKYGPRNVIEPYKSLRERRKKMVSTTEDNQHRKELLEYKPSNNIDIP 484
P+ K + S R++ + E + E +E S IP
Sbjct: 414 RNQIIEV--PWLNRKLISEGATPKFHSERQKDIMSGNDIEGSASYFEEIEDTISGPDSIP 471
Query: 485 PAYSKLQMIYGKFGVMDFDFGGFNTTQYSGLETDIDCVYINEIIHLYRFVPEVYNFVVNC 544
Y + + Y KFG+ DFDFG +N T+Y+GLETDI Y N ++ L +VP ++
Sbjct: 472 KFYQRPVIKYSKFGIEDFDFGFYNKTKYAGLETDITNSYCNSVLQLLSYVPSFSKAAISH 531
Query: 545 LEDEHIQEKSVLTELGFLFDMMTRANGKICRASNFVDVLESISTANELGLFTDEISTVSG 604
+ +L ELGFLF M+ + G+ C+A+NF+ +
Sbjct: 532 SLGPCDLMECLLCELGFLFAMLKESTGRNCQATNFLRAFSN------------------- 572
Query: 605 HAGKPSLDEGNLSSHIYNLNLSVDADAEEIMKRSYGKYMTVAQKFNIFLL---DRLISEE 661
SS +L + D ++ S+ V QKF F+L R+ E
Sbjct: 573 ------------SSFAQSLGIVFDDYSDGTFPDSF-----VIQKFTKFMLTEISRIADYE 615
Query: 662 VERKLHSTDAIVLEELFGLNVDTEIHTLSTCGNFVRQPHXXXXXXXXXPASNNVKYSNKK 721
++ S L + F + + + + CG ++ ++ Y +++
Sbjct: 616 DKKDGTSFPVSFLLKSFCIP-EMQTYRCGICGITSQKIKSSLYII-------DLHYPSQQ 667
Query: 722 LSNQTILPYI-ESSMCRFKQLTAR-CSKCEKLQNQEYESIVRNLPPLLSLNICLSPEEWT 779
L + ++ + S+ R L C C Q S +R+LP L +N + E
Sbjct: 668 LESILSFEWLFKMSLDRRVDLPPGWCEYCLAHQPFLLRSFIRSLPDCLFINTQVKHHEHW 727
Query: 780 TAKTVNGWLSNHFFATISKDRPILKLQATDLKTSN------AIFKYELMSYVARITDDFG 833
WL D +Q K SN ++ Y L + I +
Sbjct: 728 KLWARKNWLPKKLHLRRVNDT----MQCVSQKISNLDKDQQSLSVYVLRGIIYEIRQNGE 783
Query: 834 EEHLVTYAKILDQKIQQY----KWYMFNDFLVQEIDEDEALNISYWWKTPEIVVYSDAEE 889
E H V+ ++ D +WY+FNDFLV+E+ E+EAL + WK P IV Y +
Sbjct: 784 EPHFVSTIRVSDNTSSDNPDDNRWYIFNDFLVKEVTEEEALTVHGPWKIPIIVYYEKLDT 843
Query: 890 IRKPFVSVSKLKVDTDILYRDYFSEGIRKDVIRQYRLLTKDEAPGPGTLVALDAEFVSLT 949
+ VS D +LY+ Y + I + + LT DE P LV +D+EFV+L
Sbjct: 844 KIPQWDEVS----DYTLLYQPYSLN--KNPPINKIQPLTTDEMLYPKMLVGIDSEFVALQ 897
Query: 950 EPYLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGI 1009
+ E+ G K+ +KP+K SLARVS+LRGEG +G+PFIDDY+ + + DYLT++SGI
Sbjct: 898 QEETEVRSDGTKSTIKPSKLSLARVSVLRGEGPNKGLPFIDDYVATDDKVTDYLTEYSGI 957
Query: 1010 EPGDLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDT-S 1068
PGDLDP S ++V +V Y+K+ LL+ GC+FVGHGL DFR IN+ VP Q+ DT
Sbjct: 958 HPGDLDPDRSPYNVVPLKVAYKKLRLLVNAGCIFVGHGLQKDFRIINLLVPPEQVVDTVD 1017
Query: 1069 LYYLKGK-RYLSLRYLAFAVLRKQVQTGNHDSIEDAHTAXXXXXXXXXXXXXGVFEMYLE 1127
L++L + R LSL++LA+ +L +++Q HDSIEDA TA G E L+
Sbjct: 1018 LFFLSSRQRKLSLKFLAWYLLDEEIQLTEHDSIEDALTALKLYDCYDKLKSQGKLEETLD 1077
Query: 1128 NIYDEGRKFGFKVP 1141
NIY+ GR+F F+ P
Sbjct: 1078 NIYEVGRRFKFRPP 1091
>Hs7662258 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1115
Score = 299 bits (765), Expect = 2e-80
Identities = 292/1132 (25%), Positives = 464/1132 (40%), Gaps = 227/1132 (20%)
Query: 37 FDTEANLIWAGDSYGRVSSY-DPTYSLYTRHTAHIGSMPVVDLLSNKNGILSLSSDSLHF 95
FD ++W G G +S+ P Y+ + GS + + S +NGIL L+ ++L +
Sbjct: 81 FDLHEEMLWVGSHGGHATSFFGPALERYSSFQVN-GSDDIRQIQSLENGILFLTKNNLKY 139
Query: 96 SNRRGVTQMSLTSADIAQLSDMKTMCYYTNNQNQVLCAGGNTASGIISVDLIKGTLASST 155
R G+ L + + M + L GG + I+ +DL T+ +
Sbjct: 140 MARGGLIIFDYL------LDENEDMHSLLLTDSSTLLVGG-LQNHILEIDL--NTVQETQ 190
Query: 156 YF---TSKVKHMSSNNKLVAIGKQAGSIDLFDPVSNRVIHSLSGHSASITSMDFKDNTLV 212
+ T V M N+ G +G + L D + +V H S S++ D N L
Sbjct: 191 KYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLA 250
Query: 213 TAGKSKTFGYLQSDQFINVYDVRIMKQLPPISFSKTPNFVGNHTSSKFPIGADFLQLHPV 272
G S L D+F+ VYD+R+M+ + P+ P F L+ P
Sbjct: 251 ACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAF---------------LRFIPT 295
Query: 273 LPTVVAVASSSGSFDFID---LVNPSLRTPYIHPCKSISQ-FTLSPSGDYLAFLEEESMI 328
+ +A+ S SG F + L NP+ +++P + F +S S LAF + E +
Sbjct: 296 YTSRLAIISQSGQCQFCEPTGLANPA-DIFHVNPVGPLLMTFDVSASKQALAFGDSEGCV 354
Query: 329 NMWNRSNSMSGFTNSAAVLEYQDYPEDSFIPYRVEV----------------GQESYPLS 372
++W D PE SF PY E Q+ PLS
Sbjct: 355 HLWT------------------DSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLS 396
Query: 373 SIGLPYYSETLLSAWPHTVFKTXXXXXXXXXXXXXXXTDNNSTKXXXXXXXXXXXXXXXX 432
I +P ++TLLS WP NS
Sbjct: 397 LIPVPLTTDTLLSDWPAA----------------------NSAPAPRRAPPVDAEILRTM 434
Query: 433 QPYNKFKYGP------RNVIEPYKSLRERRKKMVS---TTEDNQHRKELLEYKPSNNIDI 483
+ Y P RN I PY+ L+E + S TE R+E +P ++ +
Sbjct: 435 KKVGFIGYAPNPRTRLRNQI-PYR-LKESDSEFDSFSQVTESPVGREE----EPHLHM-V 487
Query: 484 PPAYSKLQMIYGKFGVMDFDFGGFNTTQYSGLETDIDCVYINEIIHLYRFVPEVYNFVVN 543
Y K+ + Y K G+ DFDF +N T ++GLE I Y N +I + F+ V
Sbjct: 488 SKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPV-----R 542
Query: 544 CLEDEHIQEKS--VLTELGFLFDMMTRANGKICRASNFVDVLESISTANELGLFTDEIST 601
CL H+ +K + ELGFLF M+ + G C+ +NF+ +I A+ LGL +
Sbjct: 543 CLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDE 602
Query: 602 VSGHAGKPSLDEGNLSSHIYNLNLSVDADAEEIMKRSYGKYMTVAQKFNIFLLDRLISEE 661
SG +GNL+ I Q++N F+L +L +
Sbjct: 603 ASG--------KGNLARLI--------------------------QRWNRFILTQLHQDM 628
Query: 662 VERKLH-----------STDAIVLEELFGLNVDTEIHTLSTCGNFVRQPHXXXXXXXXXP 710
E ++ S+ V+ +LF + + E +L CG+ + P
Sbjct: 629 QELEIPQAYRGAGGSFCSSGDSVIGQLF--SCEMENCSLCRCGSETVRASSTLLFTLSYP 686
Query: 711 ASNNVKYSNKKLSNQTILPYIESSMCRFKQLTARCSKCEKLQNQEYESIVRNLPPLLSLN 770
+ S+K N ++ S+C + A C CEK Q +R+LP +L +N
Sbjct: 687 DGSK---SDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVIN 743
Query: 771 ICL-------------------------------------------SPEEWTTAKTV--- 784
+ SPE ++
Sbjct: 744 CEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEEL 803
Query: 785 -NGWLSNHFFATISKDRPILKLQATD----------LKTSNAIFKYELMSYVARITDDFG 833
N WL ++K++ + TD + + ++ Y+LM+ V I D
Sbjct: 804 KNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRT 863
Query: 834 EEHLVTYAKILD------QKIQQYKWYMFNDFLVQEIDEDEALNISYWWKTPEIVVYSDA 887
LV + K+ + + + +WY+FNDFL++ ID+ EA+ WK P I+ Y
Sbjct: 864 GGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKR 923
Query: 888 EEIRKPFVSVSKLKVDTDILYRDYFSEGIRKDVIRQYRLLTKDEAPGPGTLVALDAEFVS 947
+ +++ K ++ +L + ++ + L +E P G LV LDAEFV+
Sbjct: 924 NLNSRYNLNI-KNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVT 982
Query: 948 LTEPYLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFS 1007
L E E+ G K+ +KP++ S+AR++ +RG+G EG+PFIDDYI + + DYLTQ+S
Sbjct: 983 LNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYS 1042
Query: 1008 GIEPGDLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGLTNDFRQINIYV 1059
GI+PGDLD K+S K L + Y K+ L+ +G FVGHGL DFR IN+ V
Sbjct: 1043 GIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMV 1094
>7303975 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1209
Score = 209 bits (533), Expect = 2e-53
Identities = 119/312 (38%), Positives = 170/312 (54%), Gaps = 19/312 (6%)
Query: 850 QYKWYMFNDFLVQEIDEDEALNISYWWKTPEIVVYSDAEEIRKPFVSVSKLKVDTDILYR 909
Q +WY+FNDF + + E++ + WK P I+ Y E+ + + S +++
Sbjct: 897 QSQWYIFNDFSISPVSPQESVWFTLDWKVPCILFYRHVEDDSESASTTSSTVTESEETIP 956
Query: 910 DYFSEGIRKDVIRQY------------------RLLTKDEAPGPGTLVALDAEFVSLTEP 951
S G ++ + + L DE P G LVA+DAEFV+L
Sbjct: 957 SESSSGSPTNLSNPFLEEIVSPMLGNLSADATLQPLQSDEMPQSGDLVAMDAEFVTLNPE 1016
Query: 952 YLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGIEP 1011
EI G +KP S+AR+S +RG+G EGVPF+DDYI + + DYLTQFSGI+P
Sbjct: 1017 ENEIRPDGKTATIKPCHMSVARISCIRGQGPAEGVPFMDDYISTQEKVVDYLTQFSGIKP 1076
Query: 1012 GDLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDT-SLY 1070
GDLD SKK L + Y+K+ L+ +G +FVGHGL NDFR INIYVP QI DT L+
Sbjct: 1077 GDLDANFSKKRLTALKYSYQKLKYLVDVGVIFVGHGLKNDFRVINIYVPSEQIIDTVHLF 1136
Query: 1071 YLKGKRYLSLRYLAFAVLRKQVQTGNHDSIEDAHTAXXXXXXXXXXXXXGVFEMYLENIY 1130
++ R +SLR+LA+ L ++Q+ HDSIEDA T F L+N+Y
Sbjct: 1137 HMPHHRMVSLRFLAWHFLGTKIQSETHDSIEDARTTLQLYKHYLKLQEEKKFANALKNLY 1196
Query: 1131 DEGRKFGFKVPD 1142
+ G++ +KVP+
Sbjct: 1197 ERGKQLQWKVPE 1208
Score = 89.4 bits (220), Expect = 3e-17
Identities = 90/378 (23%), Positives = 164/378 (42%), Gaps = 49/378 (12%)
Query: 32 VTKVVFDTEANLIWAGDSYGRVSSY-DPTYSLYTRHTAHIGSMPVVDLLSNKNGILSLSS 90
V+ V FD L+W G+ G V+SY + YT H + V D+ + +G+L+L+
Sbjct: 64 VSSVAFDDYEELLWMGNQGGHVTSYYTNSMQKYTSFQVHATDI-VRDISTLDSGVLALTQ 122
Query: 91 DSLHFSNRRGVTQMSLTSADIAQLSDMKTMCYYTNNQNQVLCAGGNTASGIISVDLIKGT 150
SL RRG+ + + S ++ ++ M + + ++++ AG +I DL
Sbjct: 123 TSLRHQIRRGLPKFTFKSNNMKEMVSMLQL-----SPHRLVMAG--LQDELIDFDL---- 171
Query: 151 LASSTYFTSKVKHMSS--------NNKLVAIGKQAGSIDLFDPVSNRVIHSLSGHSASIT 202
T ++++H+ + N++ + G Q G++ L D S V H++ H+ ++
Sbjct: 172 ---RTLKETRIEHVGAGGCTVLRKNSRYLFAGDQLGTVTLRDLNSLSVQHTIKTHTNILS 228
Query: 203 SMDFKDNTLVTAGKSKTFGYLQSDQFINVYDVRIMKQLPPISFSKTPNFVGNHTSSKFPI 262
+ N L++ G S L D+F+ VYD+R+++ + PI P
Sbjct: 229 DFSVQGNLLISCGYSGRQNNLAIDRFLMVYDLRMLRLIAPIQVMIDP------------- 275
Query: 263 GADFLQLHPVLPTVVAVASSSGSFDFIDLVNPSLRTPYIHPCKS----ISQFTLSPSGDY 318
L+ P L + +AV SS G +D V S ++ + F +S S
Sbjct: 276 --QMLKFLPSLTSQLAVVSSYGQVQLVDTVELSEPRVSMYQINTNGSQCLSFDISSSSQA 333
Query: 319 LAFLEEESMINMWNR-SNSMSGFTNSAAVLEYQDYPEDSFIPYRVEVGQESYPLSSIGLP 377
+AF ++ INM F + E+ D +P V + ++PLSS+ LP
Sbjct: 334 MAFGDQSGHINMIAAVQTPQPQFNLYSRSTEFADVVPQ--LP-MVSITDTNFPLSSVMLP 390
Query: 378 YYS--ETLLSAWPHTVFK 393
+ + S WP + +
Sbjct: 391 HLTTGTQWFSDWPEELLR 408
Score = 77.8 bits (190), Expect = 9e-14
Identities = 79/305 (25%), Positives = 133/305 (42%), Gaps = 51/305 (16%)
Query: 483 IPPAYSKLQMIYGKFGVMDFDFGGFNTTQYSGLETDIDCVYINEIIHLYRFVPEVYNFVV 542
IP Y K+++ Y K G DFDF N T ++GLE + Y N ++ + F + V
Sbjct: 475 IPRRYRKVELKYTKLGTQDFDFDQHNQTCFAGLEATLPNSYCNAMLQILYFTDALR---V 531
Query: 543 NCLEDEHIQEKSVLTELGFLFDMMTRANGKI-CRASNFVDVLESISTANELGL-FTDEIS 600
LE I+E + ELGFLF+M+ ++ C+ASNF+ ++ A+ LGL TD S
Sbjct: 532 KLLEHSCIKEFCLSCELGFLFNMLDKSTASSPCQASNFLRSFRTVPEASALGLILTDRSS 591
Query: 601 TV--------SGHAGKPSLDEGNLSSHIYNLNLSVDADAEEIMKRSYGKYMTVAQKFNIF 652
V + +AG E + SS +Y+ ++S + E+ +RS
Sbjct: 592 NVNLISLIQATENAGS---SETSGSSDLYD-SISDENSKEDDRERS-------------- 633
Query: 653 LLDRLISEEVERKLHSTDAIVLEELFGLNVDTEIHTLSTCGNFVRQPHXXXXXXXXXPAS 712
++ +E K+ T I + + ++ N
Sbjct: 634 ---KINAETDISKIFGTKQICINRCIKCQEEKIKESILLACNL--------------SYP 676
Query: 713 NNVKYSNKKLSNQTILPYIESSMCRFKQLTARCSKCEKLQNQEYESIVRNLPPLLSLNIC 772
N++K S++ + TIL + S+ K + A C +C+K V +LP +LS+N
Sbjct: 677 NHIKDSDQYFNFGTIL---KRSLSSEKSIQAFCERCKKFSPTNQSVKVTSLPQILSINCG 733
Query: 773 LSPEE 777
L+ E+
Sbjct: 734 LNNEK 738
>CE01269 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1131
Score = 125 bits (315), Expect = 3e-28
Identities = 97/324 (29%), Positives = 154/324 (46%), Gaps = 26/324 (8%)
Query: 813 SNAIFKYELMSY-VARITDDFGEEHLVTYAKILDQKIQQYKWYMFNDFLVQEIDEDEALN 871
S I++ + M + V +D H VT + + + W + N+ LV + + EA +
Sbjct: 791 SAVIYELDAMIHAVGNGENDVNWTHPVTLLR--ESPVISSSWTLINEQLVSRLHDHEARH 848
Query: 872 ISYWWKTPEIVVYSDAEEIRKPFVSVSKLKVDTDILYRDYF--SEGIRKDVIRQYRLLTK 929
I WK P ++ Y +K F +K DI+ D F E + + + + +
Sbjct: 849 IDGRWKLPALLAYK-----KKNF----DVKTSEDIISNDLFLAEENLASNGMTSLAVQSL 899
Query: 930 DEAPGPGTLVALDAEFVSLTEPYLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPFI 989
+E P LV LDAEF+ + LE + K ++ +++ R S + GE
Sbjct: 900 EELPKEKELVGLDAEFIKIKTDLLEFDGKTVQM------RAVGRASCVDSTGERI---IF 950
Query: 990 DDYI--INECHIEDYLTQFSGIEPGDLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHG 1047
DD++ ++ + DYLT+FSGI DL P S+K L + +M +L+Q G FVGH
Sbjct: 951 DDHVKLTDDVEVVDYLTKFSGIVKADLCPTTSEKYLTTHKRLLLRMHVLIQRGVTFVGHA 1010
Query: 1048 LTNDFRQINIYVPESQIRDT-SLYYLKGKRYLSLRYLAFAVLRKQVQTGNHDSIEDAHTA 1106
L NDF +N++V ESQI DT +L L +R LSL++L +L + +Q HDS+ DA A
Sbjct: 1011 LHNDFTVLNVHVAESQIIDTVTLMRLGTQRMLSLQFLVKEILGETIQMEAHDSVVDARYA 1070
Query: 1107 XXXXXXXXXXXXXGVFEMYLENIY 1130
G+ + IY
Sbjct: 1071 LKLYRKYLEIKEQGLLGSEMRRIY 1094
Score = 75.9 bits (185), Expect = 3e-13
Identities = 82/366 (22%), Positives = 148/366 (40%), Gaps = 19/366 (5%)
Query: 29 EKQVTKVVFDTEANLIWAGDSYGRVSSYDPTYSLYTRHTAHIGS--MPVVDLLSNKNGIL 86
E V+ V FD +L W G S G+V+S PT + +TR++A + S V L ++ I
Sbjct: 25 ENTVSCVKFDPHEDLFWIGSSTGKVTSLLPT-NHFTRYSAFVVSNISGVHSLEPTESLIF 83
Query: 87 SLSSDSLHFSNRRGVTQMSLTSADIAQLSDMKTMCYYTNNQNQVLCAGGNTASGIISVDL 146
+LS L + R+G+ TS + + M C+ ++ G +I D
Sbjct: 84 TLSDTMLRATTRQGIPVAKFTSPSMTK---MAASCHMPGTSTFIM---GGFQEKLIHYDF 137
Query: 147 IKGTLASSTYFTSK----VKHMSSNNKLVAIGKQAGSIDLFDPVSNRVIHSLSGHSASIT 202
+K +T + + + N A + G++ + + + IH+L H +
Sbjct: 138 VKEKEIRTTELKASENAIIIRYNGTNTFTADTR--GNVFVKNSKNCETIHTLDCHQDQVL 195
Query: 203 SMDFKDNTLVTAGKSKTFGYLQSDQFINVYDVRIMKQLPPISFSKTPNFVGNHTSSKFPI 262
D + N L+T G S DQFI VYD+R+ K L PI P F S +
Sbjct: 196 DFDVQGNKLITCGVSMN-RLKNMDQFIKVYDLRMYKALSPIGMPYLPQFARFMPSYCERV 254
Query: 263 GADFLQLHPVLPTVVAVASSSGSFDFIDLVNPSLRTPYIHPCKSISQFTLSPSGDYLAFL 322
+ ++ ++ DL + + IS F S + +++A
Sbjct: 255 CVTYQTMYNQPGQTATWSNHPAGVKMFDLNSNGNSAEFPIETSLISAFDFSSNKNFIAVG 314
Query: 323 EEESMINMWNRSNSMSGFTNSAAVLEYQDYPEDSFIPYRVEVGQESYPLSSIGLPYYSET 382
++N++ + NS + + P + + ++ +++ SI L + E
Sbjct: 315 NHCGIVNVFADRDQPQVNENSKETV-FAAPPVQPPLSFAIDDTTQTF--GSIPLGFSQEP 371
Query: 383 LLSAWP 388
L+S WP
Sbjct: 372 LVSDWP 377
>At3g15080 [L] KOG2249 3'-5' exonuclease
Length = 273
Score = 70.1 bits (170), Expect = 2e-11
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 28/170 (16%)
Query: 939 VALDAEFVSLTEPYLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPFIDDYIINECH 998
VA+D E V +++ K +L RV+L+ G + D+++ H
Sbjct: 82 VAMDCEMVGVSQG---------------TKSALGRVTLVNKWGNV----LYDEFVRPVEH 122
Query: 999 IEDYLTQFSGIEPGDLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGLTNDFRQINIY 1058
+ D+ T SGI P DL + +V K+ L++ G + VGH L ND + + +
Sbjct: 123 VVDFRTSISGIRPRDL------RKAKDFRVAQTKVAELIK-GKILVGHALHNDLKALLLT 175
Query: 1059 VPESQIRDTSLY--YLKGKRYLSLRYLAFAVLRKQVQTGNHDSIEDAHTA 1106
P+ IRDT Y +LKGK SL++LA +L +Q G H I+DA A
Sbjct: 176 HPKKDIRDTGEYQPFLKGKTRKSLKHLASEILGADIQNGEHCPIDDARAA 225
>Hs13569960 [L] KOG2249 3'-5' exonuclease
Length = 353
Score = 68.6 bits (166), Expect = 6e-11
Identities = 52/167 (31%), Positives = 82/167 (48%), Gaps = 24/167 (14%)
Query: 948 LTEPYLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFS 1007
L + I+C+ + T K SLAR S++ G++ D+YI+ CHI DY T++S
Sbjct: 175 LPRKMVAIDCEMVGTGPKGHVSSLARCSIVNYNGDV----LYDEYILPPCHIVDYRTRWS 230
Query: 1008 GIEPGDLDPKLSKKSLVKRQVFY--RKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIR 1065
GI K+ +V F R L + G + VGH + NDF+ + + P+S R
Sbjct: 231 GIR---------KQHMVNATPFKIARGQILKILTGKIVVGHAIHNDFKALQYFHPKSLTR 281
Query: 1066 DTSLYYLKGKR-------YLSLRYLAFAVLRKQVQTG--NHDSIEDA 1103
DTS ++ +SL++L +L + +Q G H S+EDA
Sbjct: 282 DTSHIPPLNRKADCPENATMSLKHLTKKLLNRDIQVGKSGHSSVEDA 328
>7294419 [L] KOG2249 3'-5' exonuclease
Length = 290
Score = 68.2 bits (165), Expect = 7e-11
Identities = 50/141 (35%), Positives = 70/141 (49%), Gaps = 16/141 (11%)
Query: 971 LARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGIEPGDLDPKLSKKSLVKRQVFY 1030
LARVS++ G + +D Y+ + DY T SGI P D+ + V+ +V
Sbjct: 136 LARVSIVNRMGHV----LLDKYVKPRKEVTDYRTSVSGIRPQDI-ANGEDFAAVQNEV-- 188
Query: 1031 RKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLY-----YLKGKRYLSLRYLAF 1085
+ L G + VGHGL ND + I P IRDTS Y + SL+ L
Sbjct: 189 ----MKLIHGRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLISNTHTPSLKRLTK 244
Query: 1086 AVLRKQVQTGNHDSIEDAHTA 1106
AVL +++QTG H+S+EDA A
Sbjct: 245 AVLGQEIQTGEHNSVEDARAA 265
>Hs21362094 [L] KOG2249 3'-5' exonuclease
Length = 325
Score = 67.0 bits (162), Expect = 2e-10
Identities = 62/187 (33%), Positives = 87/187 (46%), Gaps = 34/187 (18%)
Query: 929 KDEAPGPGTLVALDAEFVSLTEPYLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPF 988
K P P VA+D E V T P ++ LAR S++ G++
Sbjct: 101 KASGPLPSKCVAIDCEMVG-TGPRGRVS-------------ELARCSIVSYHGDV----L 142
Query: 989 IDDYIINECHIEDYLTQFSGIEPGDLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGL 1048
D YI E I DY T++SGI + + V QV +++ LL+ G V VGH L
Sbjct: 143 YDKYIRPEMPIADYRTRWSGIT------RQHMRKAVPFQVAQKEILKLLK-GKVVVGHAL 195
Query: 1049 TNDFRQINIYVPESQIRDTSLY-------YLKGKRYLSLRYLAFAVLRKQVQTG--NHDS 1099
NDF+ + P SQ RDT+ L + +SL+ LA +L K++Q G H S
Sbjct: 196 HNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSS 255
Query: 1100 IEDAHTA 1106
+EDA TA
Sbjct: 256 VEDATTA 262
>Hs22057667 [L] KOG2249 3'-5' exonuclease
Length = 325
Score = 66.2 bits (160), Expect = 3e-10
Identities = 62/187 (33%), Positives = 86/187 (45%), Gaps = 34/187 (18%)
Query: 929 KDEAPGPGTLVALDAEFVSLTEPYLEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPF 988
K P P VA+D E V T P ++ LAR S++ G +
Sbjct: 101 KASGPLPSKCVAIDCEMVG-TGPRGRVS-------------ELARCSIVSYHGNV----L 142
Query: 989 IDDYIINECHIEDYLTQFSGIEPGDLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGL 1048
D YI E I DY T++SGI + + V QV +++ LL+ G V VGH L
Sbjct: 143 YDKYIRPEMPIADYRTRWSGIT------RQHMRKAVPFQVAQKEILKLLK-GKVVVGHAL 195
Query: 1049 TNDFRQINIYVPESQIRDTSLY-------YLKGKRYLSLRYLAFAVLRKQVQTG--NHDS 1099
NDF+ + P SQ RDT+ L + +SL+ LA +L K++Q G H S
Sbjct: 196 HNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSS 255
Query: 1100 IEDAHTA 1106
+EDA TA
Sbjct: 256 VEDATTA 262
>HsM12232443 [L] KOG2249 3'-5' exonuclease
Length = 209
Score = 63.9 bits (154), Expect = 1e-09
Identities = 52/145 (35%), Positives = 74/145 (50%), Gaps = 20/145 (13%)
Query: 971 LARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGIEPGDLDPKLSKKSLVKRQVFY 1030
LAR S++ G++ D YI E I DY T++SGI + + V QV
Sbjct: 13 LARCSIVSYHGDV----LYDKYIRPEMPIADYRTRWSGIT------RQHMRKAVPFQVAQ 62
Query: 1031 RKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLY-------YLKGKRYLSLRYL 1083
+++ LL+ G V VGH L NDF+ + P SQ RDT+ L + +SL+ L
Sbjct: 63 KEILKLLK-GKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTRARVSLKDL 121
Query: 1084 AFAVLRKQVQTG--NHDSIEDAHTA 1106
A +L K++Q G H S+EDA TA
Sbjct: 122 ALQLLHKKIQVGQHGHSSVEDATTA 146
>Hs13569913 [L] KOG2248 3'-5' exonuclease
Length = 774
Score = 63.9 bits (154), Expect = 1e-09
Identities = 53/142 (37%), Positives = 76/142 (53%), Gaps = 17/142 (11%)
Query: 969 KSLARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGIEPGDLDPKLSKKSLVKRQV 1028
+ L R+SL+ EG G +D+ + E I DYLT FSGI L+P +K V+RQ
Sbjct: 242 RELTRISLV-AEG---GCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQ- 296
Query: 1029 FYRKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLYYLK--GKRYLSLRYLAFA 1086
+ LL V VGH L D R + + P + DTSL Y++ G+R+ L++LA
Sbjct: 297 ----LKALLPPDAVLVGHSLDLDLRALKMIHP--YVIDTSLLYVREQGRRF-KLKFLAKV 349
Query: 1087 VLRKQVQTGN---HDSIEDAHT 1105
+L K +Q + HD+ EDA T
Sbjct: 350 ILGKDIQCPDRLGHDATEDART 371
>YOL080c [L] KOG2249 3'-5' exonuclease
Length = 289
Score = 58.5 bits (140), Expect = 6e-08
Identities = 53/209 (25%), Positives = 93/209 (44%), Gaps = 37/209 (17%)
Query: 901 KVDTDILYRDYFSEGIRKDVIRQYRLLTKDEAPGPGTLVALDAEFVSLTEPYLEINCKGM 960
K +T ++ GI +D + +++ G +A+D EFV + E
Sbjct: 89 KANTSTTIKEPVKVGISEDT-----RINSNKSKEIGKYIAMDCEFVGVGPEGKE------ 137
Query: 961 KTLLKPAKKSLARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGIEPGDLDPKLSK 1020
+LAR+S++ G + +D+++ + ++ T SGI+P + ++
Sbjct: 138 --------SALARISIVNYFGHV----VLDEFVKPREKVVEWRTWVSGIKPEHMKNAITF 185
Query: 1021 KSLVKRQVFYRKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLY------YLKG 1074
K K+ + G + VGH L +D + + P+S +RDTS + Y KG
Sbjct: 186 KEAQKKTADILE-------GRILVGHALKHDLEALMLSHPKSLLRDTSRHLPFRKLYAKG 238
Query: 1075 KRYLSLRYLAFAVLRKQVQTGNHDSIEDA 1103
K SL+ L VL+ +Q G H S+EDA
Sbjct: 239 KT-PSLKKLTREVLKISIQEGEHSSVEDA 266
>Hs9966857_2 [L] KOG2249 3'-5' exonuclease
Length = 252
Score = 56.2 bits (134), Expect = 3e-07
Identities = 50/159 (31%), Positives = 78/159 (48%), Gaps = 17/159 (10%)
Query: 953 LEINCKGMKTLLKPAKKSLARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGIEPG 1012
L ++C+ + K + ARVS++ G+ D Y+ + DY T SGI P
Sbjct: 74 LALDCEMVGVGPKGEESMAARVSIVNQYGKC----VYDKYVKPTEPVTDYRTAVSGIRPE 129
Query: 1013 DLDPKLSKKSLVKRQVFYRKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLY-- 1070
+L K + +V +++ +L+ G + VGH L ND + + + P+ +IRDT Y
Sbjct: 130 NL------KQGEELEVVQKEVAEMLK-GRILVGHALHNDLKVLFLDHPKKKIRDTQKYKP 182
Query: 1071 ---YLKGKRYLSLRYLAFAVLRKQVQTGNHDSIEDAHTA 1106
+K R SLR L+ +L QVQ H SI+DA A
Sbjct: 183 FKSQVKSGR-PSLRLLSEKILGLQVQQAEHCSIQDAQAA 220
>YGR276c [L] KOG2248 3'-5' exonuclease
Length = 553
Score = 55.8 bits (133), Expect = 4e-07
Identities = 46/172 (26%), Positives = 81/172 (46%), Gaps = 13/172 (7%)
Query: 971 LARVSLLRGEGELEGVPFIDDYIINECHIEDYLTQFSGIEPGDLDPKLSKKSLVKRQVFY 1030
L R+SL+ + E+ ++ + + I DYLT++SGI L +KK+L + Q
Sbjct: 241 LTRISLVNFDNEV----IYEELVKPDVPIVDYLTRYSGITEEKLTVG-AKKTLREVQ--- 292
Query: 1031 RKMWLLLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLYY--LKGKRYL-SLRYLAFAV 1087
+ + ++ + +GH L ND + + + P + DT++ Y G + SL+YL+
Sbjct: 293 KDLLKIISRSDILIGHSLQNDLKVMKLKHP--LVVDTAIIYHHKAGDPFKPSLKYLSETF 350
Query: 1088 LRKQVQTGNHDSIEDAHTAXXXXXXXXXXXXXGVFEMYLENIYDEGRKFGFK 1139
L K +Q G HDS+EDA + EN++ + +F K
Sbjct: 351 LNKSIQNGEHDSVEDARACLELTKLKILNGLAFGIGINTENLFTKLHRFEVK 402
>YLR107w [L] KOG2248 3'-5' exonuclease
Length = 404
Score = 54.3 bits (129), Expect = 1e-06
Identities = 25/68 (36%), Positives = 43/68 (62%), Gaps = 2/68 (2%)
Query: 1036 LLQLGCVFVGHGLTNDFRQINIYVPESQIRDTSLYYLKGKRYLSLRYLAFAVLRKQVQTG 1095
L+ + +GHGL ND + ++ +++ DT++ Y + K +SL+ LAF VL +++Q G
Sbjct: 317 LINKNSILIGHGLENDLNVMRLF--HNKVIDTAILYSRTKFKVSLKNLAFEVLSRKIQNG 374
Query: 1096 NHDSIEDA 1103
HDS +DA
Sbjct: 375 EHDSSQDA 382
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,288,390
Number of Sequences: 60738
Number of extensions: 2839671
Number of successful extensions: 7855
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 7783
Number of HSP's gapped (non-prelim): 29
length of query: 1144
length of database: 30,389,216
effective HSP length: 117
effective length of query: 1027
effective length of database: 23,282,870
effective search space: 23911507490
effective search space used: 23911507490
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)