ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4973 check: MH D KOG4593 Cell cycle control, cell division, chromosome partitioning Mitotic checkpoint protein MAD1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4973 1703466 1705409 648
(648 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL086w [D] KOG4593 Mitotic checkpoint protein MAD1 513 e-145
SPBC3D6.04c [D] KOG4593 Mitotic checkpoint protein MAD1 167 4e-41
Hs22062407 [D] KOG4593 Mitotic checkpoint protein MAD1 100 7e-21
Hs4505065 [D] KOG4593 Mitotic checkpoint protein MAD1 95 4e-19
7291892 [Z] KOG0161 Myosin class II heavy chain 88 4e-17
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 83 1e-15
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 77 1e-13
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 75 2e-13
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 75 3e-13
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 73 1e-12
CE09349 [Z] KOG0161 Myosin class II heavy chain 73 1e-12
SPCC645.05c [Z] KOG0161 Myosin class II heavy chain 72 3e-12
CE07306 [Z] KOG0161 Myosin class II heavy chain 70 8e-12
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 70 1e-11
Hs13124879 [Z] KOG0161 Myosin class II heavy chain 70 1e-11
Hs13124875 [Z] KOG0161 Myosin class II heavy chain 70 1e-11
Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and relat... 69 3e-11
CE12204 [Z] KOG0161 Myosin class II heavy chain 68 4e-11
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 67 8e-11
CE06253 [Z] KOG0161 Myosin class II heavy chain 67 8e-11
At1g79280 [S] KOG4674 Uncharacterized conserved coiled-coil protein 67 8e-11
Hs4557773 [Z] KOG0161 Myosin class II heavy chain 67 1e-10
At1g73860 [Z] KOG0239 Kinesin (KAR3 subfamily) 67 1e-10
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 66 1e-10
ECU04g1000 [Z] KOG0161 Myosin class II heavy chain 66 1e-10
Hs15313972 [Z] KOG0161 Myosin class II heavy chain 66 2e-10
Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription fact... 65 2e-10
YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC... 65 3e-10
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 65 3e-10
SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil p... 65 4e-10
Hs20542063 [Z] KOG0161 Myosin class II heavy chain 64 5e-10
Hs20558376 [Z] KOG0161 Myosin class II heavy chain 64 7e-10
Hs13124877 [Z] KOG0161 Myosin class II heavy chain 64 7e-10
CE20196 [Z] KOG0161 Myosin class II heavy chain 64 7e-10
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 64 9e-10
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 63 1e-09
Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing pro... 63 1e-09
SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115 63 2e-09
Hs4505301 [Z] KOG0161 Myosin class II heavy chain 62 4e-09
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 61 5e-09
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 61 5e-09
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 61 5e-09
YLR086w [BD] KOG0996 Structural maintenance of chromosome protei... 61 6e-09
Hs17978507 [Z] KOG0161 Myosin class II heavy chain 61 6e-09
Hs14764231 [D] KOG0018 Structural maintenance of chromosome prot... 60 8e-09
Hs4505993 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 60 1e-08
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 60 1e-08
YHR023w [Z] KOG0161 Myosin class II heavy chain 59 2e-08
Hs5453642 [D] KOG0018 Structural maintenance of chromosome prote... 59 2e-08
Hs20532997 [Z] KOG0161 Myosin class II heavy chain 59 2e-08
Hs12667788 [Z] KOG0161 Myosin class II heavy chain 59 2e-08
Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 59 2e-08
Hs4502781_1 [Z] KOG0242 Kinesin-like protein 59 2e-08
Hs7705348 [Z] KOG0247 Kinesin-like protein 59 3e-08
CE09197 [Z] KOG0161 Myosin class II heavy chain 59 3e-08
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 58 4e-08
Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 58 4e-08
Hs11128045_1 [TU] KOG1029 Endocytic adaptor protein intersectin 58 4e-08
Hs4505541 [U] KOG0946 ER-Golgi vesicle-tethering protein p115 58 5e-08
Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved ... 57 7e-08
YPR141c [Z] KOG0239 Kinesin (KAR3 subfamily) 57 9e-08
CE03665 [Z] KOG0161 Myosin class II heavy chain 57 9e-08
Hs4504949 [W] KOG1836 Extracellular matrix glycoprotein Laminin ... 57 1e-07
CE08691 [U] KOG0999 Microtubule-associated protein Bicaudal-D 57 1e-07
7295043 [Z] KOG0161 Myosin class II heavy chain 57 1e-07
7294128 [S] KOG0992 Uncharacterized conserved protein 57 1e-07
7301391 [Z] KOG1850 Myosin-like coiled-coil protein 56 1e-07
7297163 [R] KOG0249 LAR-interacting protein and related proteins 56 1e-07
7292701_2 [S] KOG4415 Uncharacterized conserved protein 56 2e-07
Hs4759006 [U] KOG0993 Rab5 GTPase effector Rabaptin-5 55 3e-07
At5g49880 [D] KOG4593 Mitotic checkpoint protein MAD1 55 3e-07
At1g04600 [Z] KOG0160 Myosin class V heavy chain 55 3e-07
7294543 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-intera... 55 3e-07
YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein 55 3e-07
YFL008w [D] KOG0018 Structural maintenance of chromosome protein... 55 3e-07
Hs19924131 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 55 3e-07
Hs19924129 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 55 3e-07
At3g18480 [K] KOG0963 Transcription factor/CCAAT displacement pr... 55 3e-07
At4g27180 [Z] KOG0239 Kinesin (KAR3 subfamily) 54 6e-07
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 54 6e-07
SPAC4A8.05c [Z] KOG0161 Myosin class II heavy chain 54 7e-07
SPAC27D7.13c [ZR] KOG4568 Cytoskeleton-associated protein and re... 54 7e-07
At5g48600 [BD] KOG0996 Structural maintenance of chromosome prot... 54 7e-07
7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in ... 54 7e-07
Hs4758648 [Z] KOG0240 Kinesin (SMY1 subfamily) 53 1e-06
YKL179c [K] KOG0963 Transcription factor/CCAAT displacement prot... 53 2e-06
Hs5453591 [BD] KOG0933 Structural maintenance of chromosome prot... 53 2e-06
At3g44050 [Z] KOG4280 Kinesin-like protein 53 2e-06
7303314 [S] KOG0992 Uncharacterized conserved protein 53 2e-06
YIL144w [D] KOG0995 Centromere-associated protein HEC1 52 2e-06
SPAC688.11 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-int... 52 2e-06
Hs18560881 [Z] KOG0244 Kinesin-like protein 52 2e-06
CE20131 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase... 52 2e-06
At5g54670 [Z] KOG0239 Kinesin (KAR3 subfamily) 52 2e-06
7298332 [BD] KOG0996 Structural maintenance of chromosome protei... 52 2e-06
7296991 [DY] KOG0977 Nuclear envelope protein lamin intermediate... 52 2e-06
SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPas... 52 3e-06
Hs20484473 [S] KOG4725 Uncharacterized conserved protein 52 3e-06
CE04916 [KRT] KOG4572 Predicted DNA-binding transcription factor... 52 3e-06
7292323 [S] KOG4643 Uncharacterized coiled-coil protein 52 3e-06
YBL047c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 52 4e-06
SPBC146.03c [BD] KOG0996 Structural maintenance of chromosome pr... 52 4e-06
CE02790 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase... 52 4e-06
7294443 [DZ] KOG0971 Microtubule-associated protein dynactin DCT... 52 4e-06
Hs4505983 [R] KOG0249 LAR-interacting protein and related proteins 51 5e-06
SPCC364.04c [K] KOG0963 Transcription factor/CCAAT displacement ... 51 6e-06
Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein 51 6e-06
Hs20373153 [Z] KOG0161 Myosin class II heavy chain 51 6e-06
CE21149 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC... 51 6e-06
CE04618 [Z] KOG0161 Myosin class II heavy chain 51 6e-06
At5g60930 [Z] KOG0244 Kinesin-like protein 51 6e-06
YJL074c [D] KOG0964 Structural maintenance of chromosome protein... 50 8e-06
HsM4885113 [BD] KOG0996 Structural maintenance of chromosome pro... 50 8e-06
Hs7305205 [Z] KOG0244 Kinesin-like protein 50 8e-06
Hs21361252 [BD] KOG0996 Structural maintenance of chromosome pro... 50 8e-06
At2g27170 [D] KOG0964 Structural maintenance of chromosome prote... 50 8e-06
7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein 50 8e-06
7303173 [DY] KOG0977 Nuclear envelope protein lamin intermediate... 50 8e-06
>YGL086w [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 749
Score = 513 bits (1320), Expect = e-145
Identities = 289/696 (41%), Positives = 424/696 (60%), Gaps = 74/696 (10%)
Query: 19 QLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENI 78
Q R++ LQ+K TLQNEYEI KL +++T L+ KY +++ELE AL DTK LYE N
Sbjct: 59 QSNRQIQALQFKLNTLQNEYEIEKLQLQKQTNILEKKYKATIDELEKALNDTKYLYESND 118
Query: 79 KLKEELKS---KDALPKED-EKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVT 134
KL++ELKS + A D +K I LRT +L+N K+ + L + SK ++VT
Sbjct: 119 KLEQELKSLKERSANSMNDKDKCIEELRT---TLQN----KDLEMETLRQQYDSKLSKVT 171
Query: 135 NAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNN 194
N + KLE E S ++L ++E +I + +I+ LQ ++ EK++ +S +++ + SH N
Sbjct: 172 NQCDHFKLEAESSHSLLMKYEKEIKRQSVDIKDLQHQVMEKDDELSSVKASKMINSHPNY 231
Query: 195 STEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL 254
STEE +L +NK +++Q+ Y KELE N++QA ELKKL+Q+ D + K ENE LQ+KL
Sbjct: 232 STEEFNELTEMNKMIQDQVQYTKELELANMQQANELKKLKQSQDTSTFWKLENEKLQNKL 291
Query: 255 DQLNSLQKKFESLEMENISLQEKITQWGI------------------------------- 283
QL+ L+ ++E+L++ENI L+ K+T+W I
Sbjct: 292 SQLHVLESQYENLQLENIDLKSKLTKWEIYNDSDDDDDNNVNNNDNNNNNKNDNNNDNNN 351
Query: 284 -------VRLDGKFK-----NPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEM 331
+ + + K NP ++I + + ++E L D N KL++D N + +LNDEM
Sbjct: 352 DTSNNNNINNNNRTKNNIRNNPEEIIRDWKLTKKECLILTDMNDKLRLDNNNLKLLNDEM 411
Query: 332 AIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEEC-----------XXXXXXXXXX 380
A+ERNQ+LDLNK+YE +I+NLKRLNHELEQQK LSFEEC
Sbjct: 412 ALERNQILDLNKNYENNIVNLKRLNHELEQQKSLSFEECRLLREQLDGLYSAQNNALLEV 471
Query: 381 XXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQ---KRRKITND 437
+ +N+I+ YKN+TEDLTNELK+LN++L + ++ K+RK+T+D
Sbjct: 472 ENSETHASNKNVNEDMNNLIDTYKNKTEDLTNELKKLNDQLLSNSNDVETQRKKRKLTSD 531
Query: 438 -LGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLL 496
+G++YSQ S + +L++K+ LT LKEKK+RILQLRD P +
Sbjct: 532 QIGLNYSQRLNELQLENVSVSRELSKAQTTIQLLQEKLEKLTKLKEKKIRILQLRDGPFI 591
Query: 497 KEHYIRKEKLALLEKENSDLLSGIE-----TDAIPRSVYDRIKHDMKLLEKEIFSANKKT 551
K+ +I+K KL LLEKEN+DLL+ ++ + +P SVYD + ++K E+E+F +NK+
Sbjct: 592 KDQFIKKNKLLLLEKENADLLNELKKNNPAVETVPISVYDSLNFELKQFEQEVFKSNKRF 651
Query: 552 TRLKEVFNKKSLEFIEAVNSLLGFKLEFLAHGKVKLVSCYQPNKYIIADLQSNTLKSDLD 611
+RLK+VFN KSLEFI+ VNSLLGFKLEF +VK+ SC++P KY+IADL NTLKS+LD
Sbjct: 652 SRLKQVFNNKSLEFIDVVNSLLGFKLEFQQDSRVKIFSCFKPEKYLIADLNENTLKSNLD 711
Query: 612 KVIPEWETLFQLYVIEKGELPAFLSQVKLRLWELSQ 647
I W+ L L+V ++G+LP FL+ + LRLWE Q
Sbjct: 712 ADIEGWDDLMNLWVEDRGQLPCFLATITLRLWEQRQ 747
>SPBC3D6.04c [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 689
Score = 167 bits (424), Expect = 4e-41
Identities = 170/683 (24%), Positives = 302/683 (43%), Gaps = 82/683 (12%)
Query: 5 PQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELE 64
P +K+ + S + + ++ +L+++ L+N+ + +L ERE LQ K + +E +
Sbjct: 39 PNLKKPSVNSANETK-NPKLASLEFQLENLKNDLKRKELEFEREQIELQRKLAEE-HEQK 96
Query: 65 NALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAH 124
N+L+ L E K+ E+ T+ + ++ ++NE KE V++
Sbjct: 97 NSLQLRLTLVE----------------KQLEEQSTSYQKEIEEVRNE---KEATQVKIHE 137
Query: 125 KLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELR- 183
L +K E I +K +IE + L + ++ + ++ L E L ++ R
Sbjct: 138 LLDAKWKE----IAELKTQIEKNDQALSEKNHEVMVSNQALQMKDTNLTNLEKLFADSRE 193
Query: 184 SVQTSASHRNNSTEELQDLAVLNKTLKEQLNYA-----------------KELEDMNLKQ 226
++T + ++LQ+L+V N+ L+E + ELE + Q
Sbjct: 194 QLETKCKELAAAEQQLQELSVHNQQLEESIKQVSSSIELEKINAEQRLQISELEKLKAAQ 253
Query: 227 ATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRL 286
++KL NN +LK+E L+SKL + + K +LE+EN +Q ++ W + +
Sbjct: 254 EERIEKLSSNNRNVEILKEEKNDLESKLYRFEEYRDKVATLELENEKIQTELNSWKSL-I 312
Query: 287 DGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNK--- 343
+ P V +L LQ N L + S L+ S L+++ A NQ L N+
Sbjct: 313 TNELPTPEAVSNKLVFLQNTNANLGERVSSLE------SQLSNKPA---NQPLGANEKDA 363
Query: 344 ----DYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNI 399
+ ET + L N L++QK L+ +E +
Sbjct: 364 AHITELETKLKELHEQNRRLQRQKSLATQEIDLLRENLKSYDDEEAILSEKNTDMKKLER 423
Query: 400 IEGYKNQTEDLTNELKRL--NEELSKTDDKI--QKRRKITNDLGISYSQXXXXXXXXXXX 455
IEG ++ +L+ + + ++ +T D++ QKRR+ Y
Sbjct: 424 IEGLVKLVDEYKLKLESMPVSLDVDETSDEVSLQKRRRKNEHKDAGY--VTELYRKNQHL 481
Query: 456 XXXXXSATKNHANILEQKIL---DLTSLKEK--------KVRILQLRDNPLLKEHYIRKE 504
T A + EQ I + +L+++ R+LQ R NP LK I+
Sbjct: 482 LFQVKEKTNIEAFLREQIITLESSIATLRQELAQVTEINSCRVLQHRSNPTLKYERIKAA 541
Query: 505 KLALLEKENSDLLSGIE---TDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKK 561
+L +L ENS L + +E D +P + + L+KE+ K+ RLKE+F+ K
Sbjct: 542 QLEMLNAENSALKALLEDKKVDCLPIQSFKIAERKALDLKKEVAEREKRIQRLKEIFSVK 601
Query: 562 SLEFIEAVNSLLGFKLEFLAHGKVKLVSCY--QPNKYIIADLQSNTLKSDLDKVIPEWET 619
SLEF EAV SL G+KL+F+ +G V++ S Y + N I D +S+T+K + PE+E
Sbjct: 602 SLEFREAVFSLFGYKLDFMPNGSVRVTSTYSREDNTAFIFDGESSTMKLVGNPSGPEFER 661
Query: 620 LFQLYVIEKGELPAFLSQVKLRL 642
L + + E+ +P L+ + L L
Sbjct: 662 LIRFWCDERKTIPGMLAALTLEL 684
>Hs22062407 [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 718
Score = 100 bits (249), Expect = 7e-21
Identities = 146/677 (21%), Positives = 276/677 (40%), Gaps = 69/677 (10%)
Query: 17 ADQLRRRVLTLQYKYTTLQNE--YEISKLSSERETYSLQNKYDKSMNELENALKDTKILY 74
A+Q+R + +Q + +Q E ++ +++ ER + Y++ ++ + L + L
Sbjct: 55 AEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQ 114
Query: 75 EENI----KLKEELKSKDALPKEDEKIITTLRTQVVSLKNE---VNLKEQRIVELAHKLS 127
E K++E+L+ + + LR + SL +N + RI EL +
Sbjct: 115 EREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVM 174
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQT 187
++ V +ES K E++ ++ H+ + N+ ++E++ Q+ + E I +L
Sbjct: 175 DQEMRVKR-LESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE---- 229
Query: 188 SASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKEN 247
+ S +E QD A++ K +K +L LE + E LR+ + LL++E
Sbjct: 230 ----QKLSLQE-QDAAIV-KNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEEL 283
Query: 248 ELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDG----KFKNPNDVITELNML 303
E LQ KL + +Q+ LE+EN L K+ W RLD + P D+ + L
Sbjct: 284 EGLQRKLGRQEKMQETLVGLELENERLLAKLQSW--ERLDQTMGLSIRTPEDLSRFVVEL 341
Query: 304 QRENTFLLDTNSKLQIDFNQM----SMLNDEMAIERNQLLDLNKDYETSILNLKRLNHEL 359
Q+ L D NS + + L +E+ QLL+ K ET +RL
Sbjct: 342 QQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQ--- 398
Query: 360 EQQKLLSFEECXXXXXXXXXXXXXXXXXXTP---GDQVNASNIIEGYKNQTEDLTNELKR 416
++ LL+ E +P A ++++ + + ++ +L +
Sbjct: 399 KRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQ 458
Query: 417 LNEEL---SKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQK 473
EEL + D ++ K+ S Q + + LE++
Sbjct: 459 ALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEE 518
Query: 474 ILDLTSLKEK----------KVRILQLRDNPLLKEHYIRKEKLALLEKENS---DLLSGI 520
L + E+ + ++L + NP +E + L+ E LL +
Sbjct: 519 KRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAM 578
Query: 521 E------TDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSLLG 574
E D + ++ L+K++ SA K RLKEVF K EF +A +L G
Sbjct: 579 ERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTG 638
Query: 575 FKLEFLAHGKVKLVSCY--QPNKYIIADLQS------NTLKSDLDKVIPEWETLFQLYVI 626
++++ + +L S Y P +I S L+++ + E L ++++
Sbjct: 639 YQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGE---LIEVHLR 695
Query: 627 EKGELPAFLSQVKLRLW 643
+ +PAFLS + L L+
Sbjct: 696 RQDSIPAFLSSLTLELF 712
>Hs4505065 [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 803
Score = 94.7 bits (234), Expect = 4e-19
Identities = 134/617 (21%), Positives = 252/617 (40%), Gaps = 59/617 (9%)
Query: 17 ADQLRRRVLTLQYKYTTLQNE--YEISKLSSERETYSLQNKYDKSMNELENALKDTKILY 74
A+Q+R + +Q + +Q E ++ +++ ER + Y++ ++ + L + L
Sbjct: 55 AEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQ 114
Query: 75 EENI----KLKEELKSKDALPKEDEKIITTLRTQVVSLKNE---VNLKEQRIVELAHKLS 127
E K++E+L+ + + LR + SL +N + RI EL +
Sbjct: 115 EREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVM 174
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQT 187
++ V +ES K +++ ++ H+ + N+ ++E++ Q+ + E I +L
Sbjct: 175 DQEMRVKR-LESEKQDVQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE---- 229
Query: 188 SASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKEN 247
+ S +E QD A++ K +K +L LE L+Q E LR+ + LL++E
Sbjct: 230 ----QKLSLQE-QDAAIV-KNMKSELVRLPRLE-RELEQLREESALREMRETNGLLQEEL 282
Query: 248 ELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDG----KFKNPNDVITELNML 303
E LQ KL + +Q+ LE+EN L K+ W RLD + P D+ + L
Sbjct: 283 EGLQRKLGRQEKMQETLVGLELENERLLAKLQSW--ERLDQTMGLSIRTPEDLSRFVVEL 340
Query: 304 QRENTFLLDTNSKLQIDFNQM----SMLNDEMAIERNQLLDLNKDYETSILNLKRLNHEL 359
Q+ L D NS + + L +E+ QLL+ K ET +RL
Sbjct: 341 QQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQ--- 397
Query: 360 EQQKLLSFEECXXXXXXXXXXXXXXXXXXTP---GDQVNASNIIEGYKNQTEDLTNELKR 416
++ LL+ E +P A ++++ + + ++ +L +
Sbjct: 398 KRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQ 457
Query: 417 LNEEL---SKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQK 473
EEL + D ++ K+ S Q + + LE++
Sbjct: 458 ALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEE 517
Query: 474 ILDLTSLKEK----------KVRILQLRDNPLLKEHYIRKEKLALLEKENS---DLLSGI 520
L + E+ + ++L + NP +E + L+ E LL +
Sbjct: 518 KRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAM 577
Query: 521 E------TDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSLLG 574
E D + ++ L+K++ SA K RLKEVF K EF +A +L G
Sbjct: 578 ERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTG 637
Query: 575 FKLEFLAHGKVKLVSCY 591
++++ + +L S Y
Sbjct: 638 YQIDITTENQYRLTSLY 654
>7291892 [Z] KOG0161 Myosin class II heavy chain
Length = 2056
Score = 88.2 bits (217), Expect = 4e-17
Identities = 127/642 (19%), Positives = 257/642 (39%), Gaps = 87/642 (13%)
Query: 7 IKEKPLESLDADQLRRRVLTL-QYKYTTLQNEYEISKLSSERETYSLQNKYDKSMN---- 61
+K + L+SLD ++ + + + + TL+ E ++ E +++K+ + +N
Sbjct: 1234 LKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSIND 1293
Query: 62 ELENALKDTKILYE-------ENIKLKEELKSKDALPKEDEKIITTLRTQVVSLK---NE 111
+LEN K +L + EN L EL+S ++ +E+++ +Q+ L+ E
Sbjct: 1294 QLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAE 1353
Query: 112 VNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQE 171
+ + E KL + +TN +E +L+ + E+Q+ E + L++E
Sbjct: 1354 IERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLT---EAQQLLEEE 1410
Query: 172 LKEKENLISELRSVQTSASHRNNSTEELQDLAVLN--KTLKEQLNYAKEL-----EDMNL 224
++K L S+LR +++ EE D A N + L E +E+ ED +L
Sbjct: 1411 TRQKLGLSSKLRQIESEKEALQEQLEE-DDEAKRNYERKLAEVTTQMQEIKKKAEEDADL 1469
Query: 225 KQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIV 284
+ E K R N D+++L ++ EL+ ++ D+L+ +KK +S E+E+ +++ + + ++
Sbjct: 1470 AKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQS-ELEDATIELEAQRTKVL 1527
Query: 285 RLDGKFKNPNDVITELNML---------------QRENTFLLDTNSKLQIDFNQMSMLND 329
L+ K KN + ++ E + + + T +L + +L F+++ L +
Sbjct: 1528 ELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLEN 1587
Query: 330 EMAIERNQLLDL-----------------NKDYETSILNLKRLNHELEQQKLLSFEECXX 372
+ +N+L DL + E+ + LK N ELE L+ E+
Sbjct: 1588 KRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLT-EDAKL 1646
Query: 373 XXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNEL--------------KRLN 418
+ A G Q DL EL K+L
Sbjct: 1647 RLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLE 1706
Query: 419 EELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLT 478
+L + + ++ K+ D + +++ A K L ++
Sbjct: 1707 GDLKEIETTMEMHNKVKED-ALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKE----- 1760
Query: 479 SLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSVY----DRIK 534
E+KV+ L+ L ++ + E E +L I +A S+ R++
Sbjct: 1761 --AERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLE 1818
Query: 535 HDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSLLGFK 576
+ LE+E+ + L + K L+ + L K
Sbjct: 1819 ARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEK 1860
Score = 67.4 bits (163), Expect = 6e-11
Identities = 88/397 (22%), Positives = 175/397 (43%), Gaps = 66/397 (16%)
Query: 13 ESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQN----KYDKSMNELENALK 68
E L+ ++ R+ L L+ +Q + +I K + QN K K + E N L
Sbjct: 1040 EQLEEEEAARQKLQLE----KVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLS 1095
Query: 69 DTKILYEENIK---------------LKEELKSKDALPKEDEKIITTLRTQVVSLKNEVN 113
T EE K L+E L +E ++ + T+V LK ++N
Sbjct: 1096 QTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLN 1155
Query: 114 LKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQH-----ETQINKHVEEI--- 165
+ ++ E+ +L+ ++ E+T + ++++ E + Q E+Q+ + E++
Sbjct: 1156 ERRVQVDEMQAQLAKREEELTQTL--LRIDEESATKATAQKAQRELESQLAEIQEDLEAE 1213
Query: 166 -----------RYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQ-L 213
R L +EL+ +N + L S+ T+A+ + ++ Q+LA L K+L+E+ +
Sbjct: 1214 KAARAKAEKVRRDLSEELEALKNEL--LDSLDTTAAQQELRSKREQELATLKKSLEEETV 1271
Query: 214 NYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENIS 273
N+ L DM K + EL + N+ +++L K + L ++K +LE EN
Sbjct: 1272 NHEGVLADMRHKHSQELNSI--NDQLENLRKAKTVLEKAK-----------GTLEAENAD 1318
Query: 274 LQEKITQWGIVRL--DGKFKNPNDVITELNM----LQRENTFLLDTNSKLQIDFNQMSML 327
L ++ R D + K I EL + ++R + L + +KLQ + ++
Sbjct: 1319 LATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQ 1378
Query: 328 NDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKL 364
+E ++ + + + E+ + ++L E +QKL
Sbjct: 1379 LEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKL 1415
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 82.8 bits (203), Expect = 1e-15
Identities = 131/579 (22%), Positives = 234/579 (39%), Gaps = 80/579 (13%)
Query: 39 EISKLSSERETYSLQN-KYDKSMNELENALKDTKI----LYEENIKLKEELKSKDALPKE 93
E L SER+T S++N K +K + +LKD++ L EE ++LKE ++ + +
Sbjct: 330 EFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESNRTIHSQLTD 389
Query: 94 DEKIITTLRTQVVSLK-------NEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEG 146
E +++ + SLK N ++ K++ + +++ +L ++ + +A + EI
Sbjct: 390 AESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSSLAHATGKL-AEINS 448
Query: 147 SGNILHQHETQINKHVEEIRYL----QQELKEKENLI----SELRSVQTSASHRNNSTEE 198
+ ++ K +++R ELKEK LI EL +++ + +E
Sbjct: 449 ERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSES 508
Query: 199 LQDLA------VLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKE------ 246
Q +LN+ K ++ Y +L ++ + TE+ + S L E
Sbjct: 509 TQSSLQSLQRDILNEKKKHEV-YESQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVA 567
Query: 247 --NELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITEL-NML 303
NEL +SK + L +L F+ +++ +Q K + LD FK N+ EL N
Sbjct: 568 TNNELSESK-NSLQTLCNAFQEKLAKSV-MQLKENEQNFSSLDTSFKKLNESHQELENNH 625
Query: 304 QRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHEL--EQ 361
Q L DT+SKLQ Q+ + + + L D N D T +L L+ N L +Q
Sbjct: 626 QTITKQLKDTSSKLQ----QLQLERANFEQKESTLSDENNDLRTKLLKLEESNKSLIKKQ 681
Query: 362 QKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDL---TNELKRLN 418
+ + S E+ N + E + E L E K L
Sbjct: 682 EDVDSLEK-------------------------NIQTLKEDLRKSEEALRFSKLEAKNLR 716
Query: 419 EELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLT 478
E + K + NDL S S K +E D
Sbjct: 717 EVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRLTANVETLTQDSK 776
Query: 479 SLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLL---SGIETDA--IPRSVYDRI 533
++K+ ++ + H +R + + ++ +N+ LL S ++TD + + I
Sbjct: 777 AMKQSFTSLVNSYQSISNLYHELRDDHVN-MQSQNNTLLESESKLKTDCENLTQQNMTLI 835
Query: 534 KHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSL 572
+ KL+ K + + K + LKEV K SL+ +SL
Sbjct: 836 DNVQKLMHKHV-NQESKVSELKEVNGKLSLDLKNLRSSL 873
Score = 77.4 bits (189), Expect = 6e-14
Identities = 148/658 (22%), Positives = 253/658 (37%), Gaps = 107/658 (16%)
Query: 16 DADQLRRRVLTLQYKYTTLQNEYEISKLSSE--RETY-SLQNKYDK---SMNELENALKD 69
D D L + + TL+ + SKL ++ RE +L+ K++ N+L ++L D
Sbjct: 683 DVDSLEKNIQTLKEDLRKSEEALRFSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLSD 742
Query: 70 TK----ILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHK 125
K IL E K E++K A + + ++ SL N Q I L H+
Sbjct: 743 AKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSY----QSISNLYHE 798
Query: 126 L-------SSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENL 178
L S+ N + + +K + E N+ Q+ T I + ++ L + +E+
Sbjct: 799 LRDDHVNMQSQNNTLLESESKLKTDCE---NLTQQNMTLI----DNVQKLMHKHVNQESK 851
Query: 179 ISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKK------ 232
+SEL+ V S DL K L+ LN A D L Q EL K
Sbjct: 852 VSELKEVNGKLS---------LDL----KNLRSSLNVAISDNDQILTQLAELSKNYDSLE 898
Query: 233 ---------LRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKIT--QW 281
L+ + LL ENE L +LD+L K + E ++ L +K+T Q
Sbjct: 899 QESAQLNSGLKSLEAEKQLLHTENEELHIRLDKLTG---KLKIEESKSSDLGKKLTARQE 955
Query: 282 GIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDL 341
I L + + + IT + E L +SKL+ D + E+ +ERN LL
Sbjct: 956 EISNLKEENMSQSQAITSVKSKLDET---LSKSSKLEADIEHLKNKVSEVEVERNALLAS 1012
Query: 342 NK----DYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNAS 397
N+ D + + N+ L E+E+++ + N
Sbjct: 1013 NERLMDDLKNNGENIASLQTEIEKKR-------------AENDDLQSKLSVVSSEYENLL 1059
Query: 398 NIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXX 457
I ED TN+LK + + + K D+ +R +L Y +
Sbjct: 1060 LISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELL 1119
Query: 458 XXXSATKNHANILEQKILDLTSLKEKKVRILQLRD--NPLLKEHYIRKEKLALLEKENSD 515
+K ++ + D LKEK + QL + N L+ L +E SD
Sbjct: 1120 ALRKKSKKQHDLCANFVDD---LKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSD 1176
Query: 516 LLSGI----ETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNS 571
L + + ++ + +V I+ D+ + E+ + K L +++ + + ++S
Sbjct: 1177 LANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQDRDDLLDS 1236
Query: 572 LLGFKLEFLAHGKVKLVSCYQPNKYIIADLQSNTLKSDLDKVIPEWETLFQLYVIEKG 629
L G + F NKY ++ L+ KS++D +P E L +V G
Sbjct: 1237 LKGCEESF--------------NKYAVS-LRELCTKSEID--VPVSEILDDNFVFNAG 1277
Score = 68.6 bits (166), Expect = 3e-11
Identities = 130/593 (21%), Positives = 235/593 (38%), Gaps = 46/593 (7%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTL--QNEYEISKLSSERETY-SLQNKYDKSMNELE 64
K LE+ D + L+ +V ++ + L NE + L + E SLQ + +K E +
Sbjct: 984 KSSKLEA-DIEHLKNKVSEVEVERNALLASNERLMDDLKNNGENIASLQTEIEKKRAEND 1042
Query: 65 NALKDTKILYEE--NIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVEL 122
+ ++ E N+ L +K K ++ + + V L +E K+QR VEL
Sbjct: 1043 DLQSKLSVVSSEYENLLLISSQTNKSLEDKTNQ--LKYIEKNVQKLLDE---KDQRNVEL 1097
Query: 123 AHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISEL 182
+L+SK ++ +K E+ + V++++ L++ N +EL
Sbjct: 1098 -EELTSKYGKLGEENAQIKDELLALRKKSKKQHDLCANFVDDLKEKSDALEQLTNEKNEL 1156
Query: 183 R-SVQTSASHRNNSTEELQDLAV----LNKTLKEQLNYAKELEDMNLKQATELKKLRQNN 237
S++ S S+ EE DLA + K+L + N + ++ EL L+++
Sbjct: 1157 IVSLEQSNSNNEALVEERSDLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKDK 1216
Query: 238 DVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVI 297
D SL + +E+ Q + D L+SL+ ES +SL+E T+ I + + N V
Sbjct: 1217 D--SLSTQYSEVCQDRDDLLDSLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNFVF 1274
Query: 298 TELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNH 357
N + +L + L FNQ++ E+ N+L + ++ + +L++L H
Sbjct: 1275 NAGNFSELSRLTVLSLENYLDA-FNQVNFKKMELD---NRLTTTDAEFTKVVADLEKLQH 1330
Query: 358 ELEQ--------QKLLSFEECXXXXXXXXXXXXXXXXXX----TPGDQVNASNIIEGYKN 405
E + +K L E T + S+ +E +
Sbjct: 1331 EHDDWLIQRGDLEKALKDSEKNFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQL 1390
Query: 406 QTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYS---QXXXXXXXXXXXXXXXXSA 462
T L N+L LN+E+ +D ++++ + L S S Q
Sbjct: 1391 ATNKLKNQLDHLNQEIRLKEDVLKEKESLIISLEESLSNQRQKESSLLDAKNELEHMLDD 1450
Query: 463 TKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIET 522
T + L +KI + S + K L L + E L+L+E S L E
Sbjct: 1451 TSRKNSSLMEKIESINSSLDDKSFELASAVEKLGALQKLHSESLSLMENIKSQLQEAKEK 1510
Query: 523 DAIPRSVYDRIKHDMKLLEKEIFSANKKTTRL--KEVFNKKSLEFIEAVNSLL 573
+ S + H++ S N +L K+ + E IE +N+LL
Sbjct: 1511 IQVDESTIQELDHEITA------SKNNYEGKLNDKDSIIRDLSENIEQLNNLL 1557
Score = 65.5 bits (158), Expect = 2e-10
Identities = 123/596 (20%), Positives = 249/596 (41%), Gaps = 85/596 (14%)
Query: 15 LDA-DQLRRRVLTLQYKYTTLQNEY-----EISKLSSERETYSLQNKYDKSMNELENALK 68
LDA +Q+ + + L + TT E+ ++ KL E + + +Q +LE ALK
Sbjct: 1294 LDAFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHEHDDWLIQR------GDLEKALK 1347
Query: 69 DT-KILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLS 127
D+ K + ++ E + S + +E +K I L +++ + N + ++ L ++
Sbjct: 1348 DSEKNFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEIR 1407
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKEN-LISELRSVQ 186
K+ +V ES+ + +E S + Q E+ + E+ ++ + K + L+ ++ S+
Sbjct: 1408 LKE-DVLKEKESLIISLEESLSNQRQKESSLLDAKNELEHMLDDTSRKNSSLMEKIESIN 1466
Query: 187 TSASHRN----NSTEELQDLAVLN-------KTLKEQLNYAKE---LEDMNLKQATELKK 232
+S ++ ++ E+L L L+ + +K QL AKE +++ +++
Sbjct: 1467 SSLDDKSFELASAVEKLGALQKLHSESLSLMENIKSQLQEAKEKIQVDESTIQELDHEIT 1526
Query: 233 LRQNNDVQSLLKKENEL--LQSKLDQLNSLQKKFES-LEMENISLQEKITQWGIVRLDGK 289
+NN L K++ + L ++QLN+L + +S ++ + + +I Q+ D +
Sbjct: 1527 ASKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLADLE 1586
Query: 290 FKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSI 349
+ + + V +EL R L T +LQ+ N+ L M +NQ+ DL+ ++
Sbjct: 1587 Y-HKSQVESELG---RSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLS 1642
Query: 350 LNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTED 409
+L+ L LE +EC SN +E ++
Sbjct: 1643 EDLRTL-RSLEDSVASLQKECKI-----------------------KSNTVESLQDVLTS 1678
Query: 410 LTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANI 469
+ L +E+S++ DKI++R L +
Sbjct: 1679 VQARNAELEDEVSRSVDKIRRRDDRCEHLSGKLKKLHSQLEEQHETFFRAEQQRMTQLGF 1738
Query: 470 LEQKILDLTS-LKEKKVRILQL--RDNPLLKEHYIR---KEKLALLEKENSDLLSGIE-T 522
L++ + LK+ +R QL R + L+ E YIR KE + L E+ L+GIE +
Sbjct: 1739 LKETVKKQEKLLKKLNLRQEQLIPRSSILVYESYIRDIEKEIIVLQER-----LNGIELS 1793
Query: 523 DAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKK--SLEFIEAVNSLLGFK 576
+P+ + F N+ + + F ++ L+F+ ++ FK
Sbjct: 1794 QQLPKGYFG-----------YFFKTNRVEMEVLDSFKQQVAKLQFLAGAEFIVKFK 1838
Score = 63.9 bits (154), Expect = 7e-10
Identities = 94/400 (23%), Positives = 174/400 (43%), Gaps = 46/400 (11%)
Query: 36 NEYEISKLSSERETYSLQNKYD-------KSMNELENALKDTKILYEENIKLKEELKSKD 88
N E+S+L+ SL+N D K M EL+N L T + + + E+L+ +
Sbjct: 1278 NFSELSRLT----VLSLENYLDAFNQVNFKKM-ELDNRLTTTDAEFTKVVADLEKLQHE- 1331
Query: 89 ALPKEDEKIITTLRTQVVSLKNEVNL--KEQRIVELAHKLSSKQNEVTNAIESMKLEIEG 146
D+ +I + +E N KE + E H L + E I + +E
Sbjct: 1332 ----HDDWLIQRGDLEKALKDSEKNFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLED 1387
Query: 147 SGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLN 206
+ ++ + Q++ +EIR + LKEKE+LI S++ S S++ L D
Sbjct: 1388 NQLATNKLKNQLDHLNQEIRLKEDVLKEKESLII---SLEESLSNQRQKESSLLD----- 1439
Query: 207 KTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFES 266
K +L + L+D + K ++ ++K+ + S L ++ L S +++L +LQK
Sbjct: 1440 --AKNELEHM--LDDTSRKNSSLMEKI---ESINSSLDDKSFELASAVEKLGALQK---- 1488
Query: 267 LEMENISLQEKITQWGIVRLDGKFKNPNDVITELN--MLQRENTF---LLDTNSKLQIDF 321
L E++SL E I + K + I EL+ + +N + L D +S ++
Sbjct: 1489 LHSESLSLMENIKS-QLQEAKEKIQVDESTIQELDHEITASKNNYEGKLNDKDSIIRDLS 1547
Query: 322 NQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXX 381
+ LN+ +A E++ + L+ + E+ IL +LE K S E
Sbjct: 1548 ENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLADLEYHK--SQVESELGRSKLKLAS 1605
Query: 382 XXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEEL 421
++++ + + +NQ +DL+N L+E+L
Sbjct: 1606 TTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDL 1645
Score = 60.8 bits (146), Expect = 6e-09
Identities = 82/450 (18%), Positives = 180/450 (39%), Gaps = 55/450 (12%)
Query: 103 TQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHV 162
TQ +L NE+ ++ L H+ N I S++L + T +
Sbjct: 130 TQKSNLLNELKQVRSKLAALEHE---------NGILSLQLSSSNKKDKNTSSVTTLTSE- 179
Query: 163 EEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDM 222
E++ Y Q++L E+ S +S S Q L V K K++ +Y K ED+
Sbjct: 180 EDVSYFQKKLTNMESNFSAKQSEAYDLSR--------QLLTVTEKLDKKEKDYEKIKEDV 231
Query: 223 NLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWG 282
+ +A+ ++ N ++ ++ +LL S +++L++ SL E +LQEK+ +
Sbjct: 232 SSIKASLAEEQASNKSLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECKTLQEKLEKCA 291
Query: 283 IVRLDGKF--KNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLD 340
I D K + ++V + + ++ + D ++++ +F+ + D ++I+ +L
Sbjct: 292 INEEDSKLLEELKHNVANYSDAIVHKDKLIEDLSTRIS-EFDNLKSERDTLSIKNEKLEK 350
Query: 341 LNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNII 400
L ++ S+ + + N +LE++ + + ++ I
Sbjct: 351 LLRNTIGSLKDSRTSNSQLEEEMV---------------------------ELKESNRTI 383
Query: 401 EGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXX 460
E + ++ N+ L + D+ Q + + S
Sbjct: 384 HSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSSLAHATGKL 443
Query: 461 SATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGI 520
+ + + +KI D +++ L N L KEK AL++K++ +L +
Sbjct: 444 AEINSERDFQNKKIKDFEKIEQDLRACLNSSSNEL-------KEKSALIDKKDQELNNLR 496
Query: 521 ETDAIPRSVYDRIKHDMKLLEKEIFSANKK 550
E + V + + ++ L+++I + KK
Sbjct: 497 EQIKEQKKVSESTQSSLQSLQRDILNEKKK 526
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 76.6 bits (187), Expect = 1e-13
Identities = 143/647 (22%), Positives = 257/647 (39%), Gaps = 83/647 (12%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALK 68
E+ E L + RR+ L+ K +L E +L + ET +L + ++ L
Sbjct: 861 ERTKEELARSEARRK--ELEEKMVSLLQEKNDLQLQVQSETENLMDAEERC-----EGLI 913
Query: 69 DTKILYEENIK-LKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLS 127
+KIL E +K L E L+ ++ + E L + SLK +++ E + ++ +
Sbjct: 914 KSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKH 973
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQT 187
+ +N+V N E M E + + ++ H + + LQ E + LI ++
Sbjct: 974 ATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLE- 1032
Query: 188 SASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQ---SLLK 244
T++L+ K L+ L AK + +LK + E +N Q L K
Sbjct: 1033 ------QQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKK 1086
Query: 245 KENEL--LQSKLD--QLNSL--QKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVIT 298
KE EL LQ+++D Q++SL QKK + L+ L+E+I +R + K +D+
Sbjct: 1087 KEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIE-KQRSDLAR 1145
Query: 299 ELNMLQRE-------NTFLLDTNSKLQIDFNQMSMLNDEMAIE--------RNQLLDLNK 343
EL + + ++ N K + +F +M +E ++ R + D
Sbjct: 1146 ELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVA 1205
Query: 344 DYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGY 403
+ I NL+R+ +LE++K E + + IE
Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALS-------------KSKSNIERT 1252
Query: 404 KNQTEDLTNELKRLNEELSKT--DDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXS 461
ED +E+K +E+ ++ D +QK R T + +S+
Sbjct: 1253 CRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSH--RVEEKESLISQLTKSKQ 1310
Query: 462 ATKNHANILEQKILDLTSLKEKKVRILQ--LRDNPLLKEHY-----IRKEKLALLEKENS 514
A L++++ + T K LQ D LL+E Y + E L K NS
Sbjct: 1311 ALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANS 1370
Query: 515 DLL---SGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNS 571
++ + ETDAI R+ + ++ K L + + A +KT E N K +
Sbjct: 1371 EVAQWKTKYETDAIQRT--EELEEAKKKLAQRLQEAEEKT----ETANSKCASLEKTKQR 1424
Query: 572 LLGFKLEFLAHGKVKLVSCYQPNKYIIADLQSNTLKSDLDKVIPEWE 618
L G + + + +C +K + + DKV+ EW+
Sbjct: 1425 LQGEVEDLMRDLERSHTACATLDK----------KQRNFDKVLAEWK 1461
Score = 56.2 bits (134), Expect = 1e-07
Identities = 77/379 (20%), Positives = 161/379 (42%), Gaps = 62/379 (16%)
Query: 14 SLDADQLRRRVLTLQYKYTTLQNEYEISKLSSER-----ETYSLQNKYDKSMNELENALK 68
+LD Q + ++K +++ E+ E E + ++N Y++ +++LE +
Sbjct: 1445 TLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504
Query: 69 DTKILYEENIKLKEELKSKDALPKEDEKII-------TTLRTQVVSLKNEVNLKEQRIVE 121
+ K L EE L E++ +E EK + L+ + ++ + +E +I+
Sbjct: 1505 ENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILR 1564
Query: 122 LAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVE-EIRYLQQELKEKENLIS 180
+ +LS ++E+ + EIE + + ++ EIR L+ K+ +
Sbjct: 1565 VQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEG 1624
Query: 181 ELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQ 240
+L ++ H N E Q +T++ QL ++ ++L A LR N D++
Sbjct: 1625 DLNEMEIQLGHSNRQMAETQRHL---RTVQGQLKDSQ----LHLDDA-----LRSNEDLK 1672
Query: 241 ---SLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVI 297
+++++ N LL +L+++ ++ E +S QE + D
Sbjct: 1673 EQLAIVERRNGLLLEELEEMKVALEQTE--RTRRLSEQELL----------------DAS 1714
Query: 298 TELNMLQRENTFLLDTNSKLQIDFNQ-MSMLNDEMAIERN--------------QLLDLN 342
+ +L +NT L++T KL+ D Q + + + + RN +L
Sbjct: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774
Query: 343 KDYETSILNLKRLNHELEQ 361
K+ +TS +L+R+ LEQ
Sbjct: 1775 KEQDTS-AHLERMKKNLEQ 1792
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 75.5 bits (184), Expect = 2e-13
Identities = 84/363 (23%), Positives = 173/363 (47%), Gaps = 47/363 (12%)
Query: 27 LQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENA---LKDTKILYEE-NIKLKE 82
LQ + + + +E+ ++ ++ + L K EL+ L + + +EE KLK+
Sbjct: 1141 LQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQ 1200
Query: 83 ELKSKDALPKEDE---KIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIES 139
+S+ L +E + + +T ++ + L++ V KE EL L K E ++ IE+
Sbjct: 1201 AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE----ELVQNLEEKVRESSSIIEA 1256
Query: 140 MKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKE------NLISELRSVQTSASHRN 193
++ S N+ +++T K ++ + L+ + KEK+ L EL+ VQ +
Sbjct: 1257 QNTKLNES-NVQLENKTSCLKETQD-QLLESQKKEKQLQEEAAKLSGELQQVQEANGDIK 1314
Query: 194 NSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSK 253
+S ++++L K L+E+L A ++ +QAT N ++Q LL K E +
Sbjct: 1315 DSLVKVEELV---KVLEEKLQAATS--QLDAQQAT-------NKELQELLVKSQENEGNL 1362
Query: 254 LDQLNSLQKKFESLEMENISLQEKITQW--GIVRLDGKF-----------KNPNDVITEL 300
+ ++ +K + LE N L+E + Q G+ L GK K+ N++ +L
Sbjct: 1363 QGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKL 1422
Query: 301 NMLQRENTFLLDTNSKLQIDFNQMSMLNDEM--AIERNQ-LLDLNKDYETSILNLKRLNH 357
Q++ L + SKL +Q+ N+E+ ++++ Q LL+ +++T + +++
Sbjct: 1423 EQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVID 1482
Query: 358 ELE 360
E++
Sbjct: 1483 EMD 1485
Score = 51.6 bits (122), Expect = 4e-06
Identities = 80/319 (25%), Positives = 128/319 (40%), Gaps = 63/319 (19%)
Query: 3 LTPQIKEKPLES---LDADQLRRRVLTLQYKY-TTLQNEYEISKLSSERETYSLQNKYDK 58
L ++EK ES ++A + +Q + T+ E + L S+++ LQ + K
Sbjct: 1239 LVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAK 1298
Query: 59 SMNELENA------LKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQ---VVSLK 109
EL+ +KD+ + EE +K+ EE K + A + D + T Q V S +
Sbjct: 1299 LSGELQQVQEANGDIKDSLVKVEELVKVLEE-KLQAATSQLDAQQATNKELQELLVKSQE 1357
Query: 110 NEVNLK-------------EQRIVELAHKLSSKQN----------EVTNAIESMKL---E 143
NE NL+ EQ EL L K+N E +ES K E
Sbjct: 1358 NEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNE 1417
Query: 144 IEGSGNILHQHETQINKHVEEI-----------RYLQQELKEKENLISELRSVQTSASHR 192
I+ Q E + + ++ LQ+ L++K+ L+ + T +
Sbjct: 1418 IQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEY 1477
Query: 193 NNSTEELQDLAVLNKTLKEQL-NYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQ 251
+E+ D A + L EQL N ELE LRQ ND Q E + L+
Sbjct: 1478 QKVIDEMDDAASVKSALLEQLQNRVAELE----------TALRQANDAQKTAYLETKELR 1527
Query: 252 SKLDQLNSLQKKFESLEME 270
+L+ L L+K E L ++
Sbjct: 1528 RQLESL-ELEKSREVLSLK 1545
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 75.1 bits (183), Expect = 3e-13
Identities = 139/632 (21%), Positives = 261/632 (40%), Gaps = 110/632 (17%)
Query: 9 EKPLESL-----DADQLRRRVLTLQYKYTTLQNEYE--ISKLSSERETYSLQNKYDKSMN 61
EK +E L D +Q + +++ K + ++EYE IS L + ET + N D+++N
Sbjct: 1021 EKNIEQLKKTISDLEQTKEEIIS---KSDSSKDEYESQISLLKEKLETATTAN--DENVN 1075
Query: 62 ELENALKDTKILYEE-----NIK--LKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNL 114
++ K + L E N+K L+ +L++ + KE ++ L+ + + L+ E
Sbjct: 1076 KISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATE 1135
Query: 115 KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQE--- 171
+Q++ L L S + E + +K E N Q+ +I++ +EI QQE
Sbjct: 1136 TKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENES 1195
Query: 172 -LKEKENLISELRSVQTSASHRNN-STEELQDLAVLNKTLKE--QLNYAKELEDMNLKQA 227
K+ + L E++++++++ ++N E+ L + K LK+ + N A LE + +
Sbjct: 1196 IKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVE- 1254
Query: 228 TELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLD 287
+E K+++ D + +KE L+ KL K+ L+ E+ ++E+ LD
Sbjct: 1255 SETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEE--------LD 1306
Query: 288 GKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYET 347
K TEL + + T L K + + +++ + E + L+ K+
Sbjct: 1307 AK-------TTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKN--- 1356
Query: 348 SILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQT 407
++ N E+++ L E +S I + Y +
Sbjct: 1357 ---EIQIKNQAFEKERKLLNE--------------------------GSSTITQEYSEKI 1387
Query: 408 EDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHA 467
L +EL RL E +I R + +S +
Sbjct: 1388 NTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDE----------------------- 1424
Query: 468 NILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENS-DLLSGIETDAIP 526
+LE+K + SL+++ IL +D + EKL +E++N DL S E
Sbjct: 1425 -LLEEKQNTIKSLQDE---ILSYKDKITRND-----EKLLSIERDNKRDLESLKEQLRAA 1475
Query: 527 RSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSLLGFKLEFLAHGKVK 586
+ +++ +K LE+E + + KE+ KK IE+ + L +E + K
Sbjct: 1476 QESKAKVEEGLKKLEEESSKEKAELEKSKEMM-KKLESTIESNETELKSSMETIRKSDEK 1534
Query: 587 LVSCYQPNKYIIADLQSNTLKSDLDKVIPEWE 618
L + + I +LQ KSDL I E E
Sbjct: 1535 LEQSKKSAEEDIKNLQHE--KSDLISRINESE 1564
Score = 73.9 bits (180), Expect = 7e-13
Identities = 147/692 (21%), Positives = 280/692 (40%), Gaps = 142/692 (20%)
Query: 15 LDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQ--------NKYDKSM----NE 62
L+ + L+YK T + E I L ET Q NK K + E
Sbjct: 816 LETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSRE 875
Query: 63 LENALKDTKILYEENIK-----------LKEELKSKDALPKEDEKIITTLRTQVVSLKNE 111
++ ++ K L +E K LKE++ +K K + + ++ Q +L E
Sbjct: 876 MQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKE 935
Query: 112 VNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEE------- 164
+ +VE + S N V E +K ++ ++E+ I K VEE
Sbjct: 936 KEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLI-KAVEESKNESSI 994
Query: 165 -IRYLQQEL----KEKENLISELRSVQTSASHRNNSTEELQDL--AVLNKT--------- 208
+ LQ ++ +EKEN E S++ + + +L+ +++K+
Sbjct: 995 QLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYES 1054
Query: 209 ----LKEQLNYAKELEDMNLKQATELKKLRQ------------NNDVQSLLK-------- 244
LKE+L A D N+ + +EL K R+ N++++ L+
Sbjct: 1055 QISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKE 1114
Query: 245 -KENE--LLQSKL----------DQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFK 291
KENE L + K+ QLNSL+ ESLE E+ L ++ ++ ++ K +
Sbjct: 1115 VKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYE-EQIANKER 1173
Query: 292 NPNDVITELN----MLQRENTFLLDTNSKLQIDFNQMSMLNDEMA-----------IERN 336
N+ I++LN Q+EN + N +L+ + M ++E + ++
Sbjct: 1174 QYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIK 1233
Query: 337 QLLDLNKDYETSIL-NLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVN 395
+L N+ E S+L ++K + E + K L +EC D++
Sbjct: 1234 ELKKKNETNEASLLESIKSVESETVKIKELQ-DECNFKEKEVSELE----------DKLK 1282
Query: 396 ASNIIEGYKNQTEDLTNELKRLNEEL-SKTDDKIQKRRKITNDLGISYSQXXXXXXXXXX 454
AS E ++ +L E +++ EEL +KT + + KITN S+
Sbjct: 1283 AS---EDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITN-----LSKAKEKSESELS 1334
Query: 455 XXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENS 514
S + +A E+++ EK +Q+++ KE + E + + +E S
Sbjct: 1335 RLKKTSSEERKNA---EEQL-------EKLKNEIQIKNQAFEKERKLLNEGSSTITQEYS 1384
Query: 515 DLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLK----EVFNKKSLEFIEAVN 570
+ ++ +E + I R++++ +L KEI + + ++ E+ +K +
Sbjct: 1385 EKINTLEDELI------RLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQD 1438
Query: 571 SLLGFKLEFLAHGKVKLVSCYQPNKYIIADLQ 602
+L +K + + KL+S + NK + L+
Sbjct: 1439 EILSYK-DKITRNDEKLLSIERDNKRDLESLK 1469
Score = 58.5 bits (140), Expect = 3e-08
Identities = 78/343 (22%), Positives = 154/343 (44%), Gaps = 36/343 (10%)
Query: 27 LQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKS 86
L YK +N+ ++ LS ER+ NK D LE+ + + E K++E LK
Sbjct: 1441 LSYKDKITRNDEKL--LSIERD-----NKRD-----LESLKEQLRAAQESKAKVEEGLKK 1488
Query: 87 KDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEG 146
L +E K L +K + E EL + + + +S K E
Sbjct: 1489 ---LEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEED 1545
Query: 147 SGNILHQHE---TQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLA 203
N+ H+ ++IN+ ++I L+ +L+ + SEL +V+ NN+ E+++ A
Sbjct: 1546 IKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVK---QELNNAQEKIRINA 1602
Query: 204 VLNKTLKEQL-NYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQK 262
N LK +L + +EL+D KQA +++ N + + LL + L+ +LD +
Sbjct: 1603 EENTVLKSKLEDIERELKD---KQA----EIKSNQEEKELLTSRLKELEQELDSTQQKAQ 1655
Query: 263 KFES---LEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQI 319
K E E+ +++ + L+ K+ ND++ + +R+ + T +
Sbjct: 1656 KSEEERRAEVRKFQVEKSQLDEKAMLLETKY---NDLVNKEQAWKRDEDTVKKTTDSQRQ 1712
Query: 320 DFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQ 362
+ +++ D + E ++L + N+D + I +L L +L+++
Sbjct: 1713 EIEKLAKELDNLKAENSKLKEANED-RSEIDDLMLLVTDLDEK 1754
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 73.2 bits (178), Expect = 1e-12
Identities = 92/373 (24%), Positives = 170/373 (44%), Gaps = 46/373 (12%)
Query: 1 MSLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSM 60
M + + K +E L + + + Q +L +E+ ++S T L KS+
Sbjct: 319 MEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS---RTSELSEAPQKSL 375
Query: 61 NELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIV 120
N L +++L KL+ E +S K + LRT V S++ + K ++
Sbjct: 376 GHEVNELTSSRLL-----KLEMENQSLT-------KTVEELRTTVDSVEGNAS-KILKME 422
Query: 121 ELAHKLSSKQNEVTNAIESMKLEIEGSGNI---LHQHETQINKHVE--------EIRYLQ 169
+ +LS K + N I K ++ N+ L + + Q+ K +E +I+ L+
Sbjct: 423 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 482
Query: 170 QELKEKENLISELRS-VQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQAT 228
QE + +S LR Q SA R E+ + +L++++KE + ++E +
Sbjct: 483 QENEHLNQTVSSLRQRSQISAEARVKDIEK--ENKILHESIKETSSKLSKIEFEKRQIKK 540
Query: 229 ELKKLRQNND-VQSL------LKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQW 281
EL+ ++ + + L L+KENELLQ K+ L +K E+LE EN L+ + +
Sbjct: 541 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRK- 599
Query: 282 GIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDL 341
+ + FKN + +L L++EN+ L + N +L+ + + + +MA QL
Sbjct: 600 -LKKTLDSFKN---LTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA----QLQLE 651
Query: 342 NKDYETSILNLKR 354
NK+ E+ LK+
Sbjct: 652 NKELESEKEQLKK 664
Score = 63.9 bits (154), Expect = 7e-10
Identities = 82/356 (23%), Positives = 150/356 (42%), Gaps = 43/356 (12%)
Query: 2 SLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQN------- 54
SLT ++E + ++L ++ + L + EI + +E SLQN
Sbjct: 396 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 455
Query: 55 ------KYDKSMNEL-ENALKDTKILYEENIKLKEELKS--------KDALPKEDEKIIT 99
+ +K++ L EN+ + KIL +EN L + + S +A K+ EK
Sbjct: 456 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENK 515
Query: 100 TLRTQVVSLKNEVNL----KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHE 155
L + ++++ K Q EL H ++ E +E+ +E +L +
Sbjct: 516 ILHESIKETSSKLSKIEFEKRQIKKELEHY--KEKGERAEELENELHHLEKENELLQKKI 573
Query: 156 TQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQ-LN 214
T + E+I L+QE E E E R ++ + N T +L+ L N L E+ L
Sbjct: 574 TNLKITCEKIEALEQENSELER---ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 630
Query: 215 YAKELEDMNLKQATELKKLRQNNDVQS---LLKKENELLQSKLDQLNSLQKKFESLEMEN 271
+ +E + + +N +++S LKK ELL++ + L+ ++ L++EN
Sbjct: 631 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 690
Query: 272 ISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSML 327
LQ+ L+ K + +EL L+ EN L +L+I ++ L
Sbjct: 691 QRLQK--------TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 738
>CE09349 [Z] KOG0161 Myosin class II heavy chain
Length = 1963
Score = 73.2 bits (178), Expect = 1e-12
Identities = 86/388 (22%), Positives = 162/388 (41%), Gaps = 44/388 (11%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
Q +K +E+ + + L++++ L+ ++E K S + + SLQ++ + +
Sbjct: 946 QRAKKKIEA-EVEALKKQIQDLEMSLRKAESE----KQSKDHQIRSLQDEMQQQDEAIAK 1000
Query: 66 ALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHK 125
K+ K E N KL E+L+S++ K+ L + L++ + +++ +L +
Sbjct: 1001 LNKEKKHQEEINRKLMEDLQSEEDKGNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQ 1060
Query: 126 LSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISEL-RS 184
+ E+ A E+ I+ SG H E + K E+ + L++++ L+S+L R
Sbjct: 1061 KRKVEGELKIAQEN----IDESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQ 1116
Query: 185 VQTSASHRNNSTEELQ------------------DLAVLNKTLKEQLNYAKELEDMNLKQ 226
++ S + EEL+ +L L + L EQ ++N K+
Sbjct: 1117 IKDGQSRISELEEELENERQSRSKADRAKSDLQRELEELGEKLDEQGGATAAQVEVNKKR 1176
Query: 227 ATELKKLRQN---------NDVQSLLKKENEL---LQSKLDQLNSLQKKFESLEMENISL 274
EL KLR++ N + L KK + L +LDQLN + K E + + +
Sbjct: 1177 EAELAKLRRDLEEANMNHENQLGGLRKKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRD 1236
Query: 275 QEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIE 334
E + GK N + + + E D S+ DF + L + E
Sbjct: 1237 AEDLAAQLDQETSGKLNN-EKLAKQFELQLTELQSKADEQSRQLQDF---TSLKGRLHSE 1292
Query: 335 RNQLLDLNKDYETSILNLKRLNHELEQQ 362
L+ +D E+ + L RL +L Q
Sbjct: 1293 NGDLVRQLEDAESQVNQLTRLKSQLTSQ 1320
>SPCC645.05c [Z] KOG0161 Myosin class II heavy chain
Length = 1526
Score = 72.0 bits (175), Expect = 3e-12
Identities = 147/668 (22%), Positives = 265/668 (39%), Gaps = 111/668 (16%)
Query: 17 ADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNK-YDKSMNELENALKDTKILYE 75
A+ RRV TLQ T LQ R LQ K + K + +++ A+K L +
Sbjct: 748 AELEERRVATLQRLMTMLQT----------RIRGFLQRKIFQKRLKDIQ-AIK----LLQ 792
Query: 76 ENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQ--RIVELAHKLSSKQN-- 131
N+++ E ++ K+ LR + S +N+ LK++ I+EL ++L +QN
Sbjct: 793 ANLQVYNEFRTFPWA-----KLFFNLRPLLSSTQNDKQLKKRDAEIIELKYELKKQQNSK 847
Query: 132 --------EVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELR 183
E N++ +++ + I E + + E + ++ E + L+
Sbjct: 848 SEVERDLVETNNSLTAVENLLTTERAIALDKEEILRRTQERLANIEDSFSETKQQNENLQ 907
Query: 184 SVQTSASHRNNSTE-ELQDLAVLNKTLKEQLNYAKE---LEDMNLKQAT-ELKKLRQNN- 237
S NN E EL + +TL + N KE LE+ +L EL+ LR+NN
Sbjct: 908 RESASLKQINNELESELLEKTSKVETLLSEQNELKEKLSLEEKDLLDTKGELESLRENNA 967
Query: 238 -------DVQSLLKKENELLQSKLDQLNSLQKKFESL--EMENISLQEKITQWGIVRLDG 288
+ K E + +K +L+ L K E++ + L + ++ +G
Sbjct: 968 TVLSEKAEFNEQCKSLQETIVTKDAELDKLTKYISDYKTEIQEMRLTNQKMNEKSIQQEG 1027
Query: 289 KFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETS 348
++ + + L+REN+ L+ S L+ ++S+L + N L + E
Sbjct: 1028 SL---SESLKRVKKLERENSTLISDVSILKQQKEELSVLKGVQELTINNLEEKVNYLEAD 1084
Query: 349 ILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTE 408
+ L +L ELE T ++ A + +
Sbjct: 1085 VKQLPKLKKELE---------------SLNDKDQLYQLQATKNKELEA---------KVK 1120
Query: 409 DLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHAN 468
+ N +K L +EL ++K Q +D + Y + S +N+
Sbjct: 1121 ECLNNIKSLTKELENKEEKCQN----LSDASLKYIE----LQEIHENLLLKVSDLENYKK 1172
Query: 469 ILEQKILDLTSLKE---------KKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSG 519
E LDL LK+ KK R L LL++ KEKL+L EN DL +
Sbjct: 1173 KYEGLQLDLEGLKDVDTNFQELSKKHRDLTFNHESLLRQSASYKEKLSLASSENKDLSN- 1231
Query: 520 IETDAIPRSVYDRIKHDMKL--LEKEIFSANKKTTRLKEVF---NKKSLEFIEAVNSLLG 574
+ ++ + V + K+ LE++I + + ++L + F +K+L L
Sbjct: 1232 -KVSSLTKQVNELSPKASKVPELERKITNLMHEYSQLGKTFEDEKRKALIASRDNEELRS 1290
Query: 575 FKLEFLAHGKVKLVSCYQPNKYIIADLQSNTLKSDLDKVIPEWETLFQLYVIEKGELPAF 634
K E K KL YQ K + + +L+S++ TL + V + + +
Sbjct: 1291 LKSEL--ESKRKLEVEYQ--KVLEEVKTTRSLRSEV--------TLLRNKVADHESIRSK 1338
Query: 635 LSQVKLRL 642
LS+V+++L
Sbjct: 1339 LSEVEMKL 1346
>CE07306 [Z] KOG0161 Myosin class II heavy chain
Length = 1974
Score = 70.5 bits (171), Expect = 8e-12
Identities = 106/475 (22%), Positives = 196/475 (40%), Gaps = 66/475 (13%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL 67
K+K D + L++ V L+ TT++ + E K + + + SLQ++ +
Sbjct: 948 KQKKKIEQDNEGLKKTVSDLE---TTIKKQ-ESEKQAKDHQIRSLQDEIQSQDEVISKLN 1003
Query: 68 KDTKILYEENIKLKEELKSKDA----LPKEDEKIITTLRTQVVSLKNEVN-----LKEQR 118
K+ K E N KL E++++++ L K K+ +TL +L+ E K++R
Sbjct: 1004 KEKKHQEEVNRKLLEDIQAEEDKVNHLNKTKAKLESTLDELEDTLEREKRGRQDCEKQRR 1063
Query: 119 IVE--------LAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQ 170
VE L +L+ ++E I+ +E+ + L ++ + K +I+ L
Sbjct: 1064 KVEGELKIAQELIEELNRHKHEQEQVIKKKDIELSSIQSRLEDEQSLVAKLQRQIKELLA 1123
Query: 171 ELKEKENLISELRSVQTSASHRNNSTEELQ-DLAVLNKTLKEQLNYAKELEDMNLKQATE 229
++E E EL + + S S + E+Q +L L L E + ++N K+ E
Sbjct: 1124 RIQELEE---ELDAERNSRSKAEKARNEMQMELEELGDRLDEAGGATQAQIELNKKREAE 1180
Query: 230 LKKLRQN---------NDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQ 280
L KLRQ+ + +L KK N+ + DQL+++QK LE E Q ++ +
Sbjct: 1181 LAKLRQDLEDAAINSETSMAALRKKHNDAVAELSDQLDTIQKMRGKLEREKNDKQREVDE 1240
Query: 281 WGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMA-------- 332
+ DV + QR+N + +L+ M++ +DE A
Sbjct: 1241 ---------LQQSADVEAK----QRQNCERM--AKQLEAQLTDMTLKSDEQARLIQELTM 1285
Query: 333 ---IERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXT 389
N+ DLN+ E + L LN ++QQ+ EE +
Sbjct: 1286 GKNKVHNENQDLNRQLEDAEAQLCALN-RIKQQQHSQLEELKRTLDQETRERQSLHSQVS 1344
Query: 390 PGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQ 444
N E ++ E+ + + +LSK + +IQ+ R G+S ++
Sbjct: 1345 -----NYQLECEQFRESLEEEQDAKTDVQRQLSKANSEIQQWRAKFEGEGVSRAE 1394
Score = 54.3 bits (129), Expect = 6e-07
Identities = 86/398 (21%), Positives = 161/398 (39%), Gaps = 36/398 (9%)
Query: 45 SERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQ 104
S+RET + + + N+LE + + T+ + EN L +ELK E K + L+
Sbjct: 1480 SQRETRAAATETFRLRNQLEESGEQTEAVKRENKALAQELKDIADQLGEGGKSVHDLQKM 1539
Query: 105 VVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEE 164
L+ E +Q + E L +++ +V M+ +IE S Q ++I K ++E
Sbjct: 1540 RRRLEIEKEELQQALDEAECALEAEEAKV------MRAQIEVS-----QIRSEIEKRLQE 1588
Query: 165 IRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELE---- 220
KE+E + +T S + + E + A L KT K+ ELE
Sbjct: 1589 --------KEEEFENTRKNHSRTIESMQVSLETESRGRAELLKTKKKLEGDVNELEIALD 1640
Query: 221 ---DMNLKQATELKKLRQN-NDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQE 276
+N+ +KKL+ ++Q +++E L D N +++ + L+ E L
Sbjct: 1641 HSNKLNVDGQKSMKKLQDTIRELQYQVEEEQRSLSESRDHANLAERRSQVLQQEKEDLAI 1700
Query: 277 KITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERN 336
Q R + + +V +N L N+ LL T K++ D + +L E+ +
Sbjct: 1701 IYEQSERTRRQAELELA-EVKDSVNELSNSNSLLLATKRKVEGD---LQLLQSEIEEAMS 1756
Query: 337 QLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNA 396
++ + +I++ +L EL ++ E D+ A
Sbjct: 1757 DAKTSDEKAKKAIMDASKLADELRSEQ----EHASNLNQSKKTLESQVKDLQMRLDEAEA 1812
Query: 397 SNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKI 434
+ I+G K Q L + L EL + + + +K+
Sbjct: 1813 AG-IKGGKRQLAKLDMRIHELETELEGENRRHAETQKV 1849
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 70.1 bits (170), Expect = 1e-11
Identities = 114/548 (20%), Positives = 235/548 (42%), Gaps = 77/548 (14%)
Query: 70 TKILYEENIKLKEELKSKD---ALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKL 126
TK+L E + +L+ LK +D +L +E+EK++ + + K NL EQ + +
Sbjct: 613 TKMLEEVSDQLRYSLKERDFFRSLVQENEKLLD-MAPATPNSKLNTNLIEQTSYQ---RS 668
Query: 127 SSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQ 186
+ ++TN +ES+K +I E + + + ++ EK N+ +L S+
Sbjct: 669 LIRLEQLTNELESLK-------SISRNKEKKFEEAISSLQL------EKSNIQLQLTSLT 715
Query: 187 TSASHRNNSTEELQDLAVLNKTLKEQLNYA----------KELEDMNLKQATEL--KKLR 234
+ S +L+ VL++ K++L+ + K++E N+ + +L
Sbjct: 716 SERSLALEKLNDLEKSLVLSERSKDELDESYKSLQEQLASKKIEVQNVSSQLSICNSQLE 775
Query: 235 QNNDVQSLLKKENELLQSKLDQ----LNSLQKKFESLEMENISLQEKITQWGIVRLDGKF 290
Q+N + LK EN LL S D+ L++L+ K SL+ +N ++ +I
Sbjct: 776 QSNHIVDNLKSENLLLTSVKDKLKADLSNLESKLSSLQQDNFHMKAQI------------ 823
Query: 291 KNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEM-AIERNQLLDLNKDYETSI 349
++ N T + N+ +L+ ++ L++ +++S +D++ + DL ++++T +
Sbjct: 824 ESSNQEYTA--TVDSMNSRILELSNDLRVANSKLSECSDDVRRLTLQNSFDL-REHQTLV 880
Query: 350 LNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVN-ASNIIEGYKNQTE 408
L L+ EL+Q ++ + Q N S +I K+ T+
Sbjct: 881 LQLQSNITELKQD--ITLQRTVRNQLEIQTTELKERLKFMEERQENLQSKLIAANKDTTQ 938
Query: 409 DLTN-ELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHA 467
+ N E++ ++ EL +T +K++ +++ Y ++
Sbjct: 939 NPDNVEVEAISIELERTKEKLRMAELEKSNIQQKYLASEKTLEMMNETHEQFKHLVESEI 998
Query: 468 NILEQKILDLTSL---KEKKVRILQLRDNPLLK------EHYIRKEKLALLEKENSDLLS 518
+ E+KI L S K+V +L+ K E +R++ AL K++ + +
Sbjct: 999 STREEKITSLRSELLDLNKRVEVLKEEKESSSKELAKQLEDAVREKDSALSFKKDYEKIR 1058
Query: 519 GIETDAIPRSVYDRIKHDMKLL-------EKEIFSANKKTTRLKEVFNKKSLEFIEAVNS 571
+ D + S+ + I+ + L+ E EI S + T +L+++ EF E
Sbjct: 1059 S-DADRVITSLKEDIEKERSLMKECHSNYESEIVSHGRTTQKLRDL----RTEFDEVNTK 1113
Query: 572 LLGFKLEF 579
L K F
Sbjct: 1114 YLKLKANF 1121
Score = 63.2 bits (152), Expect = 1e-09
Identities = 91/457 (19%), Positives = 190/457 (40%), Gaps = 55/457 (12%)
Query: 12 LESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSE---RETYSLQNKYDKSMNELE---- 64
LE++ + LR V L+++ + N+YE++ L + ++ SLQ+ D EL
Sbjct: 1191 LEAVQDNDLRELVSYLRHEKEIMDNKYELTILDNRGLNQQVKSLQSTVDSLQLELNRLQS 1250
Query: 65 -------------NALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNE 111
+ ++ ++LYE N L+++ +K +E EK + L + L+ E
Sbjct: 1251 LPVSNDQTDTPIISGSQEVQLLYESNSVLRKDNDAKLGKIQELEKEVEKLNASLNPLQTE 1310
Query: 112 VNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHE----TQINKHVEEIRY 167
+N + E+ K +S N + KL + ++L+++E TQ+ + +
Sbjct: 1311 IN---ELKAEIGAKTAS-LNLMKEYNSRWKLRFQ---SVLNKYERVDPTQLEELKKNCEA 1363
Query: 168 LQQELKEKENLISE-LRSVQTSASHRNNSTEELQDL-----AVLNKTLKEQLNYAKELED 221
L++E +E E + E + T N+ EE+++L K + + ++ E+
Sbjct: 1364 LEKEKQELETKLQETAKETDTFKQQVNSLNEEVENLKKEVEQANTKNTRLAAAWNEKCEN 1423
Query: 222 MNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQ------ 275
+ T L+Q L +N+ L SK + ++QK+ ESL+ N LQ
Sbjct: 1424 LKKSSLTRFAHLKQE------LTNKNKELTSKNAENEAMQKEIESLKDSNHQLQESASSD 1477
Query: 276 -EKITQWGIVRLDG-KFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAI 333
E+IT+ +L K + ++ N L+ + +D + K +I + + E+
Sbjct: 1478 AEQITKEQFEQLKSEKERTEKELADSKNELEHLQSEAVDADGKTEI--SNLEKEIHELRS 1535
Query: 334 ERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQ 393
++ L+ ++ + L+ H Q L + +E
Sbjct: 1536 DKEGLVQQVQNLSAELAALR--EHSPTQGSLENADEIARLRSQLESTKQYYEKEKETEIL 1593
Query: 394 VNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQK 430
S ++ + E+L N+L ++ + + +++ QK
Sbjct: 1594 AARSELVAEKEKTKEELENQLNEKSQRIKELEEQAQK 1630
Score = 56.6 bits (135), Expect = 1e-07
Identities = 111/584 (19%), Positives = 232/584 (39%), Gaps = 95/584 (16%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALK 68
+K LE + R L +K +N++ E+ET L + ++EL+
Sbjct: 469 QKSLEDCQKAKSRYEQLETLFKDKCTENKHY------EQETKDLARQVQVLLHELDLCEN 522
Query: 69 DTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSS 128
+ + K+ ++ + D I + R V E+ + Q ++ H+L+
Sbjct: 523 GIVLGVDSRKKINSYVEKSLTEDETDTDQIISSRLVVFRNIRELQQQNQNLLSAVHELAD 582
Query: 129 K-QNEVTNAIESMKLEIEGSGNILHQHET--QINKHVEEIR-YLQQELKEKE---NLISE 181
+ + + ++ +++ E ++ +ET Q+ K +EE+ L+ LKE++ +L+ E
Sbjct: 583 RMEKDEKPDLDGAEIQEE---TLIKANETIDQLTKMLEEVSDQLRYSLKERDFFRSLVQE 639
Query: 182 LRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQAT----ELKKLRQNN 237
+ A NS LN L EQ +Y + L + L+Q T LK + +N
Sbjct: 640 NEKLLDMAPATPNSK--------LNTNLIEQTSYQRSL--IRLEQLTNELESLKSISRNK 689
Query: 238 DVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVI 297
+ KK E + S + +++Q + SL E EK+ ND+
Sbjct: 690 E-----KKFEEAISSLQLEKSNIQLQLTSLTSERSLALEKL---------------NDL- 728
Query: 298 TELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNH 357
E + +L SK ++D + S L +++A ++ ++ +++ L++ NH
Sbjct: 729 --------EKSLVLSERSKDELDESYKS-LQEQLASKKIEVQNVSSQLSICNSQLEQSNH 779
Query: 358 ELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRL 417
++ K D N + + + + +++
Sbjct: 780 IVDNLK-------------SENLLLTSVKDKLKADLSNLESKLSSLQQDNFHMKAQIESS 826
Query: 418 NEELSKTDDKIQKR-RKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILD 476
N+E + T D + R +++NDL ++ S+ + H ++ Q +
Sbjct: 827 NQEYTATVDSMNSRILELSNDLRVANSKLSECSDDVRRLTLQNSFDLREHQTLVLQLQSN 886
Query: 477 LTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLS--------------GIET 522
+T LK+ + + + N L + KE+L +E+ +L S +E
Sbjct: 887 ITELKQ-DITLQRTVRNQLEIQTTELKERLKFMEERQENLQSKLIAANKDTTQNPDNVEV 945
Query: 523 DAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFI 566
+AI + +R K +++ E E K + K + ++K+LE +
Sbjct: 946 EAISIEL-ERTKEKLRMAELE-----KSNIQQKYLASEKTLEMM 983
Score = 56.6 bits (135), Expect = 1e-07
Identities = 114/611 (18%), Positives = 240/611 (38%), Gaps = 109/611 (17%)
Query: 10 KPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL-- 67
K L + ++ +L+ + L E+ K E + L + + ++ E ++AL
Sbjct: 991 KHLVESEISTREEKITSLRSELLDLNKRVEVLKEEKESSSKELAKQLEDAVREKDSALSF 1050
Query: 68 -KDTKILYEENIK----LKEELKSKDALPKE-----DEKIITTLRT--QVVSLKNEVNLK 115
KD + + + + LKE+++ + +L KE + +I++ RT ++ L+ E +
Sbjct: 1051 KKDYEKIRSDADRVITSLKEDIEKERSLMKECHSNYESEIVSHGRTTQKLRDLRTEFDEV 1110
Query: 116 EQRIVELAHKLSSKQNEVTNA--------------IESMK---LEIEGSGNILHQHETQI 158
+ ++L + + ++ A I S+K L +E +LH +Q
Sbjct: 1111 NTKYLKLKANFEQQHSGLSGAEKDWNIQRKAMEDEISSLKDYILGLENQNKLLH---SQF 1167
Query: 159 NKHVEEIRYLQQELKEKENLISELRSVQTS--------ASHRNNSTEELQDLAVL-NKTL 209
+ ++I LQQ E N+ + L +VQ + H + +L +L N+ L
Sbjct: 1168 DSLSQQITVLQQNSSENLNISANLEAVQDNDLRELVSYLRHEKEIMDNKYELTILDNRGL 1227
Query: 210 KEQLNYAKELEDMNLKQATELKKLRQNND------------------VQSLLKKENELLQ 251
+Q+ + D + L+ L +ND S+L+K+N+
Sbjct: 1228 NQQVKSLQSTVDSLQLELNRLQSLPVSNDQTDTPIISGSQEVQLLYESNSVLRKDND--- 1284
Query: 252 SKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLL 311
+KL ++ L+K+ E L LQ +I N++ E+ +
Sbjct: 1285 AKLGKIQELEKEVEKLNASLNPLQTEI---------------NELKAEIGAKTASLNLMK 1329
Query: 312 DTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECX 371
+ NS+ ++ F S+LN ++ QL +L K+ E L++ ELE + + +E
Sbjct: 1330 EYNSRWKLRF--QSVLNKYERVDPTQLEELKKNCEA----LEKEKQELETKLQETAKETD 1383
Query: 372 XXXXXXXXXXXXXXXXXTPGDQVNASN--IIEGYKNQTEDL----TNELKRLNEELSKTD 425
+Q N N + + + E+L L +EL+
Sbjct: 1384 TFKQQVNSLNEEVENLKKEVEQANTKNTRLAAAWNEKCENLKKSSLTRFAHLKQELT--- 1440
Query: 426 DKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKV 485
K +++T+ + + SA+ + I +++ L S KE+
Sbjct: 1441 ---NKNKELTSKNAENEAMQKEIESLKDSNHQLQESASSDAEQITKEQFEQLKSEKERTE 1497
Query: 486 RILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEIF 545
+ +L D+ K +L L+ E D E + + +++ ++ D + L +++
Sbjct: 1498 K--ELADS---------KNELEHLQSEAVDADGKTEISNLEKEIHE-LRSDKEGLVQQVQ 1545
Query: 546 SANKKTTRLKE 556
+ + + L+E
Sbjct: 1546 NLSAELAALRE 1556
Score = 52.4 bits (124), Expect = 2e-06
Identities = 84/369 (22%), Positives = 167/369 (44%), Gaps = 31/369 (8%)
Query: 5 PQIKEKPLESLDA-DQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNEL 63
P+ K PL +DA + +++ Y +++N+ +++++ E++ + + K +S NE
Sbjct: 21 PKTKIDPLLQVDAFTSILIPLISKSKDYESIKNDRIVTEVNYEQQLRNSEKKLLQS-NER 79
Query: 64 ENALKDTKILYEENI-KLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVEL 122
+ L+D + L E + ++KE L+ K + ++L++ +LK + ++ +L
Sbjct: 80 YDLLEDERKLLENELSQIKEYLREKSSSYDTVLHDCSSLKSVNEALKQAQDQNLKQTAQL 139
Query: 123 AHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKE-KENLISE 181
+ LS K+ EV I +K + + HQ V E+++ QQE + N E
Sbjct: 140 QNLLSDKEKEVEKKITIIKDLKDALASSTHQ--------VLELQHTQQEKASLQTNYEFE 191
Query: 182 LRSV-QTSASHRNNST---EELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNN 237
L+ + Q ++ NN+T ELQ + +L ++ + K L A L+K
Sbjct: 192 LQKLTQKNSILENNNTWLSRELQGVNDKLLSLHQEASLEKSQLSSQLSDAV-LEKDALQR 250
Query: 238 DVQSL---LKKENELLQSKLDQLNSLQKKFESLEM---ENISLQEKITQWGIVRLDGKFK 291
V SL + N Q+ + +L+ ++K++E ++ + IS Q++I++ + + +
Sbjct: 251 KVSSLSQQFTESNLRYQNIVAELSEMRKQYEFSQVSFEKEISSQKQISELWMEKCE---- 306
Query: 292 NPNDVITELNMLQRENTFLLDTNSKLQIDF-NQMSMLNDEMAIERNQLLDLNKDYETSIL 350
D L LQ N L Q F Q+ + A ++Q+ L K+ +
Sbjct: 307 ---DCSLRLKELQNSNGELEKLLEAAQSSFEEQLESHKEAEASLKSQINFLEKEVSSLES 363
Query: 351 NLKRLNHEL 359
LK N L
Sbjct: 364 QLKLANERL 372
>Hs13124879 [Z] KOG0161 Myosin class II heavy chain
Length = 1972
Score = 70.1 bits (170), Expect = 1e-11
Identities = 89/416 (21%), Positives = 178/416 (42%), Gaps = 45/416 (10%)
Query: 28 QYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL-----------KDTKILYEE 76
+ + T L+ + S E + ++ K+ +++ EL L K+ + L +E
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 77 NIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNA 136
N L EL+ +E E L QV L+++ + E+ EL K+ QNEV +
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV-ES 1291
Query: 137 IESMKLEIEGSGNILHQHETQINKHVEEIR-YLQQELKEKENLISELRSVQTSASHRNNS 195
+ M E EG L + ++ +++ + LQ+E ++K N+ ++LR ++ RN+
Sbjct: 1292 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE---EERNS- 1347
Query: 196 TEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLD 255
LQD L++ ++ + N + + +N++ + KKL+ L++ + Q +++
Sbjct: 1348 ---LQD--QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIE 1402
Query: 256 QLNSLQKK----FESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLL 311
L ++ ++ LE LQ+++ +V LD N +++ L QR+ LL
Sbjct: 1403 NLTQQYEEKAAAYDKLEKTKNRLQQELDDL-VVDLD----NQRQLVSNLEKKQRKFDQLL 1457
Query: 312 DTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKR-LNHELEQQKLLSFEEC 370
++ + A ER++ ++ ET L+L R L LE ++ L
Sbjct: 1458 AEEKN----------ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNK 1507
Query: 371 XXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDD 426
+ + +E Q E++ +L+ L +EL T+D
Sbjct: 1508 MLKAEMEDLVSSKDDVGKNVHELEKSKRALE---TQMEEMKTQLEELEDELQATED 1560
Score = 68.2 bits (165), Expect = 4e-11
Identities = 132/612 (21%), Positives = 251/612 (40%), Gaps = 83/612 (13%)
Query: 9 EKPLESLDA--DQLRRRVLTLQYKYTTLQNEYEI-----SKLSSERE---------TYSL 52
E+ LE +A +L+ +T + K L++E + +KLS ER+ T +L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL 1015
Query: 53 QNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKI----------ITTLR 102
+ +K+ N + K ++ E ++LK+E KS+ L K K+ I L+
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 103 TQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHV 162
Q+ LK ++ KE+ + +L + + NA++ ++ E+EG H + + + +
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEG-------HISDLQEDL 1127
Query: 163 EEIRYLQQEL-KEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELED 221
+ R + + K+K +L EL +++T +ST Q+L K +E K L++
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA--KREQEVTVLKKALDE 1185
Query: 222 MNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQW 281
+++++RQ + Q++ + +L Q K + N L K ++LE EN L ++
Sbjct: 1186 ETRSHEAQVQEMRQKH-AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVL 1243
Query: 282 GIVR--LDGKFKNPNDVITELNML----QRENTFLLDTNSKLQIDFNQMS-MLNDEMAIE 334
G + ++ K K + EL +R L D KLQ + ++ MLN+
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE----A 1299
Query: 335 RNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQV 394
+ + L KD + L+ +L+ + L EE + DQ+
Sbjct: 1300 EGKAIKLAKD-------VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1352
Query: 395 NASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXX 454
+ ++L + LN +LS + K+Q
Sbjct: 1353 DEE------MEAKQNLERHISTLNIQLSDSKKKLQ--------------DFASTVEALEE 1392
Query: 455 XXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENS 514
+N E+K L++ K R+ Q D+ L+ + +++ ++ LEK+
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD-LVVDLDNQRQLVSNLEKKQR 1451
Query: 515 --DLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSL 572
D L E + + +R + + + EKE A L+E K E +E N +
Sbjct: 1452 KFDQLLAEEKNISSKYADERDRAEAEAREKET-KALSLARALEEALEAK--EELERTNKM 1508
Query: 573 LGFKLEFLAHGK 584
L ++E L K
Sbjct: 1509 LKAEMEDLVSSK 1520
Score = 58.2 bits (139), Expect = 4e-08
Identities = 86/420 (20%), Positives = 167/420 (39%), Gaps = 45/420 (10%)
Query: 33 TLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPK 92
T Q E +K ++T Q K + + ELE K +++ E+N+ L+E+L+++ L
Sbjct: 848 TRQEEEMQAKEDELQKTKERQQKAENELKELEQ--KHSQLTEEKNL-LQEQLQAETELYA 904
Query: 93 EDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH 152
E E++ L K+Q + E+ H++ ++ E + + ++ E + +
Sbjct: 905 EAEEMRVRLAA-----------KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 153 QHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDL-----AVLNK 207
E Q+ + + LQ E E I +L +NN + + L + L
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 208 TLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL--------DQLNS 259
L E+ AK L + K + + +L + ++E E L+ KL +Q+
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
Query: 260 LQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQI 319
LQ + L+M+ ++ +E+ Q + RLD + N+ + ++ L+ S LQ
Sbjct: 1074 LQAQIAELKMQ-LAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-------ISDLQE 1125
Query: 320 DFNQMSMLNDEMAIERNQLLDLNKDYETSILNLK-RLNHELEQQKLLSFEECXXXXXXXX 378
D + ++ Q DL ++ E L+ L+ QQ+L + E
Sbjct: 1126 DLDSERAARNK---AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE------QEV 1176
Query: 379 XXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDL 438
T + + + + E+LT +L++ + D Q K DL
Sbjct: 1177 TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1236
Score = 52.8 bits (125), Expect = 2e-06
Identities = 100/468 (21%), Positives = 190/468 (40%), Gaps = 61/468 (13%)
Query: 18 DQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSM---NELENALKDTKILY 74
DQL + KY ++ E E + SL ++++ ELE K K
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
Query: 75 EENIKLKEEL--------KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKL 126
E+ + K+++ KSK AL + E+ ++TQ+ L++E+ E + L +
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEE----MKTQLEELEDELQATEDAKLRLEVNM 1569
Query: 127 SSKQNEVTNAIESMKLEIEGS----GNILHQHETQI-------------NKHVE-EIRYL 168
+ + + +++ + E LH++ET++ K +E +++ L
Sbjct: 1570 QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Query: 169 QQE----LKEKENLISELRSVQTSASHRNNSTEELQDLAV----LNKTLKEQLNYAKELE 220
+ + +K +E I +LR +Q + + EL+D + T KE AK LE
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQ---AQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 221 DMNLKQATELKKLRQNNDVQSLLKKEN--ELLQSKLDQLNSLQKKFESLEMENISLQEKI 278
+L Q E + Q+ L+KE E L S L N+LQ + LE L+E++
Sbjct: 1687 -ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1745
Query: 279 --TQWGIVRLDGKFKNPNDVITEL-NMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIER 335
Q + + + + +L N L E + T K + Q+ N E+ +
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERS----TAQKNESARQQLERQNKELRSKL 1801
Query: 336 NQLLDLNKD-YETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQV 394
+++ K ++++I L+ +LE+Q E +
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE-- 1859
Query: 395 NASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQK----RRKITNDL 438
+ + E YK Q E +K+L +L + +++ Q+ RRK+ +L
Sbjct: 1860 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
>Hs13124875 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 70.1 bits (170), Expect = 1e-11
Identities = 89/416 (21%), Positives = 178/416 (42%), Gaps = 45/416 (10%)
Query: 28 QYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL-----------KDTKILYEE 76
+ + T L+ + S E + ++ K+ +++ EL L K+ + L +E
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 77 NIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNA 136
N L EL+ +E E L QV L+++ + E+ EL K+ QNEV +
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV-ES 1291
Query: 137 IESMKLEIEGSGNILHQHETQINKHVEEIR-YLQQELKEKENLISELRSVQTSASHRNNS 195
+ M E EG L + ++ +++ + LQ+E ++K N+ ++LR ++ RN+
Sbjct: 1292 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE---EERNS- 1347
Query: 196 TEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLD 255
LQD L++ ++ + N + + +N++ + KKL+ L++ + Q +++
Sbjct: 1348 ---LQD--QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIE 1402
Query: 256 QLNSLQKK----FESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLL 311
L ++ ++ LE LQ+++ +V LD N +++ L QR+ LL
Sbjct: 1403 NLTQQYEEKAAAYDKLEKTKNRLQQELDDL-VVDLD----NQRQLVSNLEKKQRKFDQLL 1457
Query: 312 DTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKR-LNHELEQQKLLSFEEC 370
++ + A ER++ ++ ET L+L R L LE ++ L
Sbjct: 1458 AEEKN----------ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNK 1507
Query: 371 XXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDD 426
+ + +E Q E++ +L+ L +EL T+D
Sbjct: 1508 MLKAEMEDLVSSKDDVGKNVHELEKSKRALE---TQMEEMKTQLEELEDELQATED 1560
Score = 68.2 bits (165), Expect = 4e-11
Identities = 132/612 (21%), Positives = 251/612 (40%), Gaps = 83/612 (13%)
Query: 9 EKPLESLDA--DQLRRRVLTLQYKYTTLQNEYEI-----SKLSSERE---------TYSL 52
E+ LE +A +L+ +T + K L++E + +KLS ER+ T +L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL 1015
Query: 53 QNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKI----------ITTLR 102
+ +K+ N + K ++ E ++LK+E KS+ L K K+ I L+
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 103 TQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHV 162
Q+ LK ++ KE+ + +L + + NA++ ++ E+EG H + + + +
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEG-------HISDLQEDL 1127
Query: 163 EEIRYLQQEL-KEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELED 221
+ R + + K+K +L EL +++T +ST Q+L K +E K L++
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA--KREQEVTVLKKALDE 1185
Query: 222 MNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQW 281
+++++RQ + Q++ + +L Q K + N L K ++LE EN L ++
Sbjct: 1186 ETRSHEAQVQEMRQKH-AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVL 1243
Query: 282 GIVR--LDGKFKNPNDVITELNML----QRENTFLLDTNSKLQIDFNQMS-MLNDEMAIE 334
G + ++ K K + EL +R L D KLQ + ++ MLN+
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE----A 1299
Query: 335 RNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQV 394
+ + L KD + L+ +L+ + L EE + DQ+
Sbjct: 1300 EGKAIKLAKD-------VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1352
Query: 395 NASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXX 454
+ ++L + LN +LS + K+Q
Sbjct: 1353 DEE------MEAKQNLERHISTLNIQLSDSKKKLQ--------------DFASTVEALEE 1392
Query: 455 XXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENS 514
+N E+K L++ K R+ Q D+ L+ + +++ ++ LEK+
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD-LVVDLDNQRQLVSNLEKKQR 1451
Query: 515 --DLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSL 572
D L E + + +R + + + EKE A L+E K E +E N +
Sbjct: 1452 KFDQLLAEEKNISSKYADERDRAEAEAREKET-KALSLARALEEALEAK--EELERTNKM 1508
Query: 573 LGFKLEFLAHGK 584
L ++E L K
Sbjct: 1509 LKAEMEDLVSSK 1520
Score = 58.2 bits (139), Expect = 4e-08
Identities = 86/420 (20%), Positives = 167/420 (39%), Gaps = 45/420 (10%)
Query: 33 TLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPK 92
T Q E +K ++T Q K + + ELE K +++ E+N+ L+E+L+++ L
Sbjct: 848 TRQEEEMQAKEDELQKTKERQQKAENELKELEQ--KHSQLTEEKNL-LQEQLQAETELYA 904
Query: 93 EDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH 152
E E++ L K+Q + E+ H++ ++ E + + ++ E + +
Sbjct: 905 EAEEMRVRLAA-----------KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 153 QHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDL-----AVLNK 207
E Q+ + + LQ E E I +L +NN + + L + L
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 208 TLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL--------DQLNS 259
L E+ AK L + K + + +L + ++E E L+ KL +Q+
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
Query: 260 LQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQI 319
LQ + L+M+ ++ +E+ Q + RLD + N+ + ++ L+ S LQ
Sbjct: 1074 LQAQIAELKMQ-LAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-------ISDLQE 1125
Query: 320 DFNQMSMLNDEMAIERNQLLDLNKDYETSILNLK-RLNHELEQQKLLSFEECXXXXXXXX 378
D + ++ Q DL ++ E L+ L+ QQ+L + E
Sbjct: 1126 DLDSERAARNK---AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE------QEV 1176
Query: 379 XXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDL 438
T + + + + E+LT +L++ + D Q K DL
Sbjct: 1177 TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1236
Score = 52.8 bits (125), Expect = 2e-06
Identities = 100/468 (21%), Positives = 190/468 (40%), Gaps = 61/468 (13%)
Query: 18 DQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSM---NELENALKDTKILY 74
DQL + KY ++ E E + SL ++++ ELE K K
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
Query: 75 EENIKLKEEL--------KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKL 126
E+ + K+++ KSK AL + E+ ++TQ+ L++E+ E + L +
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEE----MKTQLEELEDELQATEDAKLRLEVNM 1569
Query: 127 SSKQNEVTNAIESMKLEIEGS----GNILHQHETQI-------------NKHVE-EIRYL 168
+ + + +++ + E LH++ET++ K +E +++ L
Sbjct: 1570 QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Query: 169 QQE----LKEKENLISELRSVQTSASHRNNSTEELQDLAV----LNKTLKEQLNYAKELE 220
+ + +K +E I +LR +Q + + EL+D + T KE AK LE
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQ---AQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 221 DMNLKQATELKKLRQNNDVQSLLKKEN--ELLQSKLDQLNSLQKKFESLEMENISLQEKI 278
+L Q E + Q+ L+KE E L S L N+LQ + LE L+E++
Sbjct: 1687 -ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1745
Query: 279 --TQWGIVRLDGKFKNPNDVITEL-NMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIER 335
Q + + + + +L N L E + T K + Q+ N E+ +
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERS----TAQKNESARQQLERQNKELRSKL 1801
Query: 336 NQLLDLNKD-YETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQV 394
+++ K ++++I L+ +LE+Q E +
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE-- 1859
Query: 395 NASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQK----RRKITNDL 438
+ + E YK Q E +K+L +L + +++ Q+ RRK+ +L
Sbjct: 1860 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
>Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1427
Score = 68.6 bits (166), Expect = 3e-11
Identities = 102/576 (17%), Positives = 247/576 (42%), Gaps = 40/576 (6%)
Query: 19 QLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENI 78
Q+ + L Q++ LQN+ + + + +E +L+ K K + E EN+L+ + ++
Sbjct: 651 QIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDK-A 709
Query: 79 KLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIE 138
+ + ++ +D L K E I +V+ K N + + I +L + + ++ +
Sbjct: 710 EDQHLVEMEDTLNKLQEAEIKVKELEVLQAK--CNEQTKVIDNFTSQLKATEEKLLDLDA 767
Query: 139 SMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISEL-RSVQTSASHRNNSTE 197
K EG + + Q+ ++I++L+ E + + S + R +Q N E
Sbjct: 768 LRKASSEGKSE-MKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 826
Query: 198 ELQDLAVLNKTLKEQLNYAKEL------EDMNLKQATE--LKKLRQNNDVQSLLKKENEL 249
L +++ + +TL+++L KE E ++++++ + + KL Q + ++L + E
Sbjct: 827 NLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEK 886
Query: 250 LQSKLDQLNSLQKKFESLEMENISLQEKITQ--WGIVRLDG----KFKNPNDVITELNML 303
L+ L + + ++ + E + I +EK+ I+++ G + ND EL +
Sbjct: 887 LRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND---ELRLK 943
Query: 304 QR--ENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQ 361
+R E L T + F Q S+ + + E++Q + K +E L+R +LE+
Sbjct: 944 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ-QEAAKKHEEEKKELERKLSDLEK 1002
Query: 362 QKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQ------VNASNIIEGYKNQTEDLTNELK 415
+ S +C Q ++ + ++G + + L EL+
Sbjct: 1003 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELE 1062
Query: 416 RLNEELSK------TDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANI 469
L ++ K +D +Q ++T + + + + +N+
Sbjct: 1063 ELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKN 1122
Query: 470 LEQ--KILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPR 527
+E+ K +L +++ +K+ + L + + ++L+ L++EN L +
Sbjct: 1123 VEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV 1182
Query: 528 SVYDRIKHDMKLLEKEIFSANKKTTR-LKEVFNKKS 562
+ + +++ + +L ++ K+ ++ +K+ +K+
Sbjct: 1183 TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKA 1218
Score = 68.2 bits (165), Expect = 4e-11
Identities = 154/709 (21%), Positives = 285/709 (39%), Gaps = 119/709 (16%)
Query: 8 KEKPLESLDADQLRRRV------------LTLQYKYTTLQNEYEISKLSSERETYSLQNK 55
K+ L + +LRRR+ L+L + ++LQ + E+++ +RE SL+
Sbjct: 506 KDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEH 565
Query: 56 YDKSMNELENALKDTKILYEENIKLKEE---LKSK-DALPKEDEKIITTLRTQVVSLKNE 111
+ E K+ K LY KL +E LKSK + KE+ +I +++ L+
Sbjct: 566 FGA---REETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSK---LETA 619
Query: 112 VNLKEQRIVELAHKLS-------SKQNEVTNAIESMKLEIEGS-GNILHQHETQINKHVE 163
+ +Q + EL S ++ E+ IE M+L+ + N+ +Q +++ H +
Sbjct: 620 IASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAK 679
Query: 164 EIRYLQQEL----KEKENLISELRSVQTSASHRN--------NSTEE----LQDLAVLNK 207
E+ L+ +L KEKEN + +RS A ++ N +E +++L VL
Sbjct: 680 EMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQA 739
Query: 208 TLKEQL----NYAKELE-------DMN-LKQA-----TELKKLRQNNDVQSLLKKENEL- 249
EQ N+ +L+ D++ L++A +E+KKLRQ + K E+
Sbjct: 740 KCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIE 799
Query: 250 LQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVR---------LDGKFKNPNDVITEL 300
++ + +S+ ++ + E++ +LQE +++ V+ L KF ++ E
Sbjct: 800 KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASE---EA 856
Query: 301 NMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELE 360
+QR + +T +KL Q +ML+ ++ R L D+ + R E E
Sbjct: 857 VSVQRS---MQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKF--------REKDERE 905
Query: 361 QQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEE 420
+Q + + E+ T ++ + + E+L +L + NE
Sbjct: 906 EQLIKAKEKLENDIAEIMKMSGDNSSQLT-----KMNDELRLKERDVEELQLKLTKANEN 960
Query: 421 LS----KTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILD 476
S +D K + + + + + N L+ +
Sbjct: 961 ASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYER 1020
Query: 477 LTS-LKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIE---TDAIPRSVYDR 532
TS K K ILQ LL ++KL +ENS LL +E A
Sbjct: 1021 ATSETKTKHEEILQNLQKTLLD----TEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1076
Query: 533 IKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSLLGFKLEFLAHGKVKLVSCYQ 592
+ M+++E+ +KT L SLE + N+ L +L+ L +K V
Sbjct: 1077 AEDAMQIMEQ---MTKEKTETL------ASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1127
Query: 593 PNKYIIADLQSNTLKSDLDKVIPEWETLFQLYVIEKGELPAFLSQ-VKL 640
+K ++ +++ E ETL Q + +L A + VKL
Sbjct: 1128 KSKELL-----TVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1171
Score = 58.5 bits (140), Expect = 3e-08
Identities = 67/321 (20%), Positives = 136/321 (41%), Gaps = 26/321 (8%)
Query: 36 NEYEISKLSSE-----RETYSLQNKYDKSMNE---LENALKDTKILYEENIKLKEELKSK 87
N +++K++ E R+ LQ K K+ L+ +++D + E++ +E K
Sbjct: 929 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQS--QQEAAKKH 986
Query: 88 DALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGS 147
+ KE E+ ++ L ++ + N+ + R + +K E+ ++ L+ E
Sbjct: 987 EEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK 1046
Query: 148 GNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNK 207
+ + + + +EE+R + K + ++ ++ + + L+D N
Sbjct: 1047 LKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA 1106
Query: 208 TLKEQLNYAKELEDMNLKQATELKKLRQ----NNDVQSLLKKENELLQSKLDQLNSLQKK 263
L+ +L+ KE NLK EL K ++ N +KE E L+ Q + ++
Sbjct: 1107 KLQNELDTLKE---NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKS---QQ 1160
Query: 264 FESLEMENISLQEKI-TQWGIVRLDGKFKNPNDVITE--LNMLQRENTFLLDTN---SKL 317
+L+ EN+ L E++ V K + V+ L M +RE+ F+ D + + L
Sbjct: 1161 LSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1220
Query: 318 QIDFNQMSMLNDEMAIERNQL 338
Q + S L E E +L
Sbjct: 1221 QKSISITSALLTEKDAELEKL 1241
Score = 55.8 bits (133), Expect = 2e-07
Identities = 70/334 (20%), Positives = 142/334 (41%), Gaps = 21/334 (6%)
Query: 3 LTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNE 62
LT E L+ D ++L+ ++ + LQ E + +E+ K+++ E
Sbjct: 933 LTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKE 992
Query: 63 LENALKDTKILYEENIKLKEELKSK-----DALPKEDEKIITTLRTQVVSLKNEVNLKEQ 117
LE L D + E + +ELK++ + E+I+ L+ ++ ++++ +
Sbjct: 993 LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE 1052
Query: 118 RIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQ---HETQINKHVEEIRY----LQQ 170
L +L + + A + E + I+ Q +T+ +E+ + LQ
Sbjct: 1053 ENSGLLQELEELRKQADKAKAAQ--TAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQN 1110
Query: 171 ELKE-KEN---LISELRSVQTSASHRNNSTEEL-QDLAVLNKTLKEQLNYAKELEDMNLK 225
EL KEN + EL + + N EE +++ L + ++ L++ N+K
Sbjct: 1111 ELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVK 1170
Query: 226 QATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKF-ESLEMENISLQEKITQWGIV 284
A EL + R L++E +L ++L ++ + KF + + E SLQ+ I+ +
Sbjct: 1171 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL 1230
Query: 285 RLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQ 318
L K + E+ +L+ EN +S +Q
Sbjct: 1231 -LTEKDAELEKLRNEVTVLRGENASAKSLHSVVQ 1263
>CE12204 [Z] KOG0161 Myosin class II heavy chain
Length = 1992
Score = 68.2 bits (165), Expect = 4e-11
Identities = 90/417 (21%), Positives = 167/417 (39%), Gaps = 43/417 (10%)
Query: 39 EISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKII 98
E K S + SLQ++ + K+ K E N KL E+L+S++ EKI
Sbjct: 1001 EQEKQSRDHNIRSLQDEMANQDEAVAKLNKEKKHQEESNRKLNEDLQSEEDKVNHLEKIR 1060
Query: 99 TTLRTQVVSLKNEVNL---------KEQRIVELAHKLSSKQ-NEVTNAIESMKLEIEGSG 148
L Q+ L+ ++ K +R VE K++ + +E+T ++ ++
Sbjct: 1061 NKLEQQMDELEENIDREKRSRGDIEKAKRKVEGDLKVAQENIDEITKQKHDVETTLKRKE 1120
Query: 149 NILHQHETQINKHVEEIRYLQQELKE--------KENLISELRSVQTSASHRNNSTEELQ 200
LH ++ ++ I LQ+ +KE +E L +E S Q S R+ + EL+
Sbjct: 1121 EDLHHTNAKLAENNSIIAKLQRLIKELTARNAELEEELEAERNSRQKSDRSRSEAERELE 1180
Query: 201 DLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNND---------VQSLLKKENELLQ 251
+L + L++Q + N K+ E+ KLR+ + + SL K+ + +
Sbjct: 1181 ELT---ERLEQQGGATAAQLEANKKREAEIAKLRREKEEDSLNHETAISSLRKRHGDSVA 1237
Query: 252 SKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLL 311
+QL +LQK E E LQ + + D + ++ D+ L ++ +
Sbjct: 1238 ELTEQLETLQKLKAKSEAEKSKLQRDLEE-SQHATDSEVRSRQDLEKALKTIEVQ----- 1291
Query: 312 DTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECX 371
S+LQ ++ S + A +N+L + N D S+ + + L + K +
Sbjct: 1292 --YSELQTKADEQSRQLQDFAALKNRLNNENSDLNRSLEEMDNQLNSLHRLKSTLQSQLD 1349
Query: 372 XXXXXXXXXXXXXXXXXTPGDQVNASNII--EGYKNQTE---DLTNELKRLNEELSK 423
+ N I E + E DLT ++ +LN E+ +
Sbjct: 1350 ETRRNYDEESRERQALAATAKNLEHENTILREHLDEEAESKADLTRQISKLNAEIQQ 1406
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 67.0 bits (162), Expect = 8e-11
Identities = 119/570 (20%), Positives = 236/570 (40%), Gaps = 68/570 (11%)
Query: 23 RVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEE---NIK 79
+V TL L+N + ++ S + SL + D S + +E+ K+LY++
Sbjct: 1070 QVKTLNLSRDQLENALKENEKSWSSQKESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTA 1129
Query: 80 LKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNA--- 136
+E+ + P + I+ TLR + L +V + E+ L K+S E+ +A
Sbjct: 1130 ADKEVNNSTNGPGLN-NILITLRRERDILDTKVTVAERDAKMLRQKISLMDVELQDARTK 1188
Query: 137 IESMKLEIEGSGNILHQHE------TQINKHVEEIRYLQQELKEKENLISELRSVQTSAS 190
+++ ++E E +I+ QH+ Q+N E L+ EL+ N EL+S
Sbjct: 1189 LDNSRVEKENHSSIIQQHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQSELDKLK 1248
Query: 191 HRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELL 250
Q++A + L L Y+ + ++ LK A E + R Q +L+K +L
Sbjct: 1249 ---------QNVAPIESEL-TALKYSMQEKEQELKLAKE-EVHRWKKRSQDILEKHEQLS 1297
Query: 251 QSKLDQLNS----LQKKFESLEMENISLQEK---ITQWGIVRLDGKFKNPNDVITELNML 303
S ++L S L+++ E+ E + +EK + + RL + + + ++N L
Sbjct: 1298 SSDYEKLESEIENLKEELENKERQGAEAEEKFNRLRRQAQERLKTSKLSQDSLTEQVNSL 1357
Query: 304 QRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQK 363
+ L ++ S+ ++ N ++A NQL + K E + + L +LE +
Sbjct: 1358 RDAKNVLENSLSEANARIEELQ--NAKVAQGNNQLEAIRKLQEDAEKASRELQAKLE-ES 1414
Query: 364 LLSFEECXXXXXXXXXX----------XXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNE 413
S+E + +Q + SNI+E K E+ ++
Sbjct: 1415 TTSYESTINGLNEEITTLKEEIEKQRQIQQQLQATSANEQNDLSNIVESMKKSFEE--DK 1472
Query: 414 LKRLNEELSKTDDKI-QKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQ 472
+K + E+ + ++KI + + ++ I+ + H + Q
Sbjct: 1473 IKFIKEKTQEVNEKILEAQERLNQPSNINMEE-------------IKKKWESEHEQEVSQ 1519
Query: 473 KILDLTSLKEKKVRI-LQLRDNPLL--KEHYIRKEKLALLEKENSDLLSGIETDAIPRSV 529
KI + +K++R+ + + N ++ K+ + KE +E+ + E D + R
Sbjct: 1520 KIREAEEALKKRIRLPTEEKINKIIERKKEELEKEFEEKVEERIKSMEQSGEIDVVLRKQ 1579
Query: 530 YD-RIKHDMKLLEKEIFSANKK-TTRLKEV 557
+ +++ K LE E NKK LK+V
Sbjct: 1580 LEAKVQEKQKELENEY---NKKLQEELKDV 1606
Score = 65.5 bits (158), Expect = 2e-10
Identities = 67/282 (23%), Positives = 126/282 (43%), Gaps = 31/282 (10%)
Query: 16 DADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYE 75
DA LR+++ + + + + + S++ E + +Q D + L +L E
Sbjct: 1167 DAKMLRQKISLMDVELQDARTKLDNSRVEKENHSSIIQQHDD-----IMEKLNQLNLLRE 1221
Query: 76 ENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTN 135
NI L+ EL++ + KE L++++ LK V E + L + + K+ E+
Sbjct: 1222 SNITLRNELENNNNKKKE-------LQSELDKLKQNVAPIESELTALKYSMQEKEQELKL 1274
Query: 136 AIESMKLEIEGSGNILHQHE----TQINKHVEEIRYLQQELKEKENLISELRS------- 184
A E + + S +IL +HE + K EI L++EL+ KE +E
Sbjct: 1275 AKEEVHRWKKRSQDILEKHEQLSSSDYEKLESEIENLKEELENKERQGAEAEEKFNRLRR 1334
Query: 185 -----VQTSASHRNNSTEELQDLAVLNKTLKEQLNYAK-ELEDM-NLKQATELKKLRQNN 237
++TS +++ TE++ L L+ L+ A +E++ N K A +L
Sbjct: 1335 QAQERLKTSKLSQDSLTEQVNSLRDAKNVLENSLSEANARIEELQNAKVAQGNNQLEAIR 1394
Query: 238 DVQSLLKKENELLQSKLDQ-LNSLQKKFESLEMENISLQEKI 278
+Q +K + LQ+KL++ S + L E +L+E+I
Sbjct: 1395 KLQEDAEKASRELQAKLEESTTSYESTINGLNEEITTLKEEI 1436
Score = 65.1 bits (157), Expect = 3e-10
Identities = 96/439 (21%), Positives = 192/439 (42%), Gaps = 55/439 (12%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETY----------SLQNKYDK 58
E + S+D+ Q + LQYK +L+ E E K+ TY SL+ + +K
Sbjct: 856 ESVITSVDSKQTD--IEKLQYKVKSLEKEIEEDKI--RLHTYNVMDETINDDSLRKELEK 911
Query: 59 SMNELENA---LKDTKILYEENIKLKEELKSK-DALPKEDEKIITTLRTQVVSLKNEVNL 114
S L +A +K+ K LYE + ++ SK D K+ I L + SL+++++L
Sbjct: 912 SKINLTDAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISL 971
Query: 115 KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRY-LQQELK 173
++++ L ++L ++ +E K + + +IL + NK VE ++ + +L
Sbjct: 972 LKEQMFNLNNELDLQKK----GMEKEKADFKKRISILQNN----NKEVEAVKSEYESKLS 1023
Query: 174 EKENLISELRSVQTSASHRNNSTEELQDLAVLNKT---LKEQLN-YAKELEDMNLKQATE 229
+ +N + + +A +NN +ELQ A ++KT L+EQL+ Y +++ +NL +
Sbjct: 1024 KIQNDLDQQTIYANTA--QNNYEQELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQL 1081
Query: 230 LKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGK 289
L++N S K +S L+QL+ + E L +N L ++I + +
Sbjct: 1082 ENALKENEKSWSSQK------ESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTAADKEVN 1135
Query: 290 FKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSI 349
+ + + R +LDT K+ + ML ++++ +L D + S
Sbjct: 1136 NSTNGPGLNNILITLRRERDILDT--KVTVAERDAKMLRQKISLMDVELQDARTKLDNS- 1192
Query: 350 LNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTED 409
+++ NH Q+ E + N +E N+ ++
Sbjct: 1193 -RVEKENHSSIIQQHDDIME------------KLNQLNLLRESNITLRNELENNNNKKKE 1239
Query: 410 LTNELKRLNEELSKTDDKI 428
L +EL +L + ++ + ++
Sbjct: 1240 LQSELDKLKQNVAPIESEL 1258
Score = 62.4 bits (150), Expect = 2e-09
Identities = 123/631 (19%), Positives = 255/631 (39%), Gaps = 112/631 (17%)
Query: 59 SMNELENALKDTKILYEENIKLKEELKSKD----ALPKEDEKIITTLRTQVVSLKNEVNL 114
S ELE ++ +L N L++EL+SK+ + ++ +K+I +R ++ L+N+ +
Sbjct: 193 SRTELERKTQELTLLQSNNDWLEKELRSKNEQYLSYRQKTDKVILDIRNELNRLRNDFQM 252
Query: 115 KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQIN-------KHVEEIRY 167
+ L K NE++ +++ LEI+G + L+ + + + + V+ +
Sbjct: 253 ERTN----NDVLKQKNNELSKSLQEKLLEIKGLSDSLNSEKQEFSAEMSLKQRLVDLLES 308
Query: 168 LQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYA----------- 216
+KE+ N I EL + + A T E +DL + KE+L
Sbjct: 309 QLNAVKEELNSIRELNTAKVIADDSKKQTPENEDLLKELQLTKEKLAQCEKECLRLSSIT 368
Query: 217 ----KELEDMNLKQATE--------LKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKF 264
++ E+++ K +++ +K+ R +Q+ ++ L+ K+ +NS +++
Sbjct: 369 DEADEDNENLSAKSSSDFIFLKKQLIKERRTKEHLQNQIETFIVELEHKVPIINSFKERT 428
Query: 265 ESLEME--NISLQEKIT----QWGIVRLDGK------FKNPNDVITELNM-LQRENTFLL 311
+ LE E N +L + T + L+ K +N +T+ + L R+ +LL
Sbjct: 429 DMLENELNNAALLLEHTSNEKNAKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLL 488
Query: 312 DTNS----------KLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQ 361
TNS K +I F Q M D+ I + + + N+ +L +
Sbjct: 489 ITNSVSNDSKGPLRKEEIQFIQNIMQEDDSTITESDSQKVVTERLVEFKNIIQLQE--KN 546
Query: 362 QKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVN-ASNIIEGYKNQTEDLTNELKRLNEE 420
+LL + VN A I K++ DL + ++ L +E
Sbjct: 547 AELLKVVRNLADKLESKEKKSKQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKE 606
Query: 421 LSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSL 480
L + + + +++N+ +++ +
Sbjct: 607 LEELKTSVP-------------------------------NEDASYSNVTIKQLTETKRD 635
Query: 481 KEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLS---------GIETDA--IPRSV 529
E +V+ LQ R + + +E E ++LL KE DL G E + +
Sbjct: 636 LESQVQDLQTRISQITRE---STENMSLLNKEIQDLYDSKSDISIKLGKEKSSRILAEER 692
Query: 530 YDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSLLGFKLEFLAHGKVKLVS 589
+ + + + L + E K+ L+ K+ + E +N + K + L+ + +L++
Sbjct: 693 FKLLSNTLDLTKAENDQLRKRFDYLQNTILKQDSKTHETLNEYVSCKSK-LSIVETELLN 751
Query: 590 CYQPNKYIIADLQSNTLKSDLDKVIPEWETL 620
+ K + L+ N LK +L+K+ PE ++L
Sbjct: 752 LKEEQK-LRVHLEKN-LKQELNKLSPEKDSL 780
Score = 62.0 bits (149), Expect = 3e-09
Identities = 92/353 (26%), Positives = 154/353 (43%), Gaps = 40/353 (11%)
Query: 12 LESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTK 71
L + DQLR+R LQ T L+ + + + +E S ++K EL N ++ K
Sbjct: 702 LTKAENDQLRKRFDYLQN--TILKQDSKTHETLNEY--VSCKSKLSIVETELLNLKEEQK 757
Query: 72 ILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQN 131
+ LK+EL P++D +LR V L+ +E + E K +
Sbjct: 758 LRVHLEKNLKQELNKLS--PEKD-----SLRIMVTQLQTLQKEREDLLEETRKSCQKKID 810
Query: 132 EVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASH 191
E+ +A+ +K E + + Q E N ++E + Q ++ E L + SV TS
Sbjct: 811 ELEDALSELKKETSQKDHHIKQLEEDNNSNIE---WYQNKI---EALKKDYESVITSVDS 864
Query: 192 RNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQ 251
+ E+LQ K+L+ KE+E+ ++ T ND L+KE E +
Sbjct: 865 KQTDIEKLQYKV---KSLE------KEIEEDKIRLHTYNVMDETIND--DSLRKELEKSK 913
Query: 252 SKLDQLNSLQKKFESL-EMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFL 310
L S K+++ L E + SLQ+ + +LD FK D ++ L E T L
Sbjct: 914 INLTDAYSQIKEYKDLYETTSQSLQQTNS-----KLDESFK---DFTNQIKNLTDEKTSL 965
Query: 311 LDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQK 363
D S L+ QM LN+E+ +++ + D++ I L+ N E+E K
Sbjct: 966 EDKISLLK---EQMFNLNNELDLQKKGMEKEKADFKKRISILQNNNKEVEAVK 1015
Score = 59.7 bits (143), Expect = 1e-08
Identities = 127/623 (20%), Positives = 242/623 (38%), Gaps = 82/623 (13%)
Query: 40 ISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKL------------KEELKSK 87
I + E ++ ++ K + E K+ L E+N +L +E KSK
Sbjct: 509 IQNIMQEDDSTITESDSQKVVTERLVEFKNIIQLQEKNAELLKVVRNLADKLESKEKKSK 568
Query: 88 DALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGS 147
+L K + + + + +++LK+E E RI EL +L + V N S
Sbjct: 569 QSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKELEELKTSVPNEDASYS------ 622
Query: 148 GNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNK 207
I + E R L+ ++++ + IS++ + S + + +E+QDL
Sbjct: 623 -------NVTIKQLTETKRDLESQVQDLQTRISQI--TRESTENMSLLNKEIQDLYDSKS 673
Query: 208 TLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL 267
+ +L K + A E KL N L K EN+ L+ + D L + K +S
Sbjct: 674 DISIKLGKEKSSRIL----AEERFKLLSN--TLDLTKAENDQLRKRFDYLQNTILKQDSK 727
Query: 268 EMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSML 327
E +L E ++ + + V TEL L+ E + L+ + N++S
Sbjct: 728 THE--TLNEYVSCKSKLSI---------VETELLNLKEEQKLRVHLEKNLKQELNKLSPE 776
Query: 328 NDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXX 387
D + I QL L K+ E +L + Q+K+ E+
Sbjct: 777 KDSLRIMVTQLQTLQKERE----DLLEETRKSCQKKIDELEDALSELKKETSQKDHHIKQ 832
Query: 388 XTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXX 447
++ N SN IE Y+N+ E L + + + + I+K + L +
Sbjct: 833 L---EEDNNSN-IEWYQNKIEALKKDYESVITSVDSKQTDIEKLQYKVKSLEKEIEEDKI 888
Query: 448 XXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRD-NPLLKEHYIRKEKL 506
N++++ I D + KE + + L D +KE+ E
Sbjct: 889 RLHTY---------------NVMDETINDDSLRKELEKSKINLTDAYSQIKEYKDLYETT 933
Query: 507 A-LLEKENSDLLSGIE--TDAIPRSVYDR--IKHDMKLLEKEIFSANKKTTRLKEVFNKK 561
+ L++ NS L + T+ I ++ ++ + LL++++F+ N + K+ K+
Sbjct: 934 SQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLLKEQMFNLNNELDLQKKGMEKE 993
Query: 562 SLEFIEAVNSLLGFKLEFLA-----HGKVKLVSCYQPNKYIIADLQSNTLKSDLDKVIPE 616
+F + ++ L E A K+ + + I A+ N + +L K
Sbjct: 994 KADFKKRISILQNNNKEVEAVKSEYESKLSKIQNDLDQQTIYANTAQNNYEQELQKHADV 1053
Query: 617 WETLFQLYVIEKGELPAFLSQVK 639
+T+ +L + +L + QVK
Sbjct: 1054 SKTISEL----REQLHTYKGQVK 1072
Score = 58.5 bits (140), Expect = 3e-08
Identities = 70/279 (25%), Positives = 132/279 (47%), Gaps = 35/279 (12%)
Query: 15 LDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQN-KYDKSMNELENALKDTKIL 73
L D L +V +L+ L+N +S+ ++ E LQN K + N+LE K L
Sbjct: 1345 LSQDSLTEQVNSLRDAKNVLENS--LSEANARIE--ELQNAKVAQGNNQLEAIRK----L 1396
Query: 74 YEENIKLKEELKSK-DALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNE 132
E+ K EL++K + E I L ++ +LK E+ + Q +L +++QN+
Sbjct: 1397 QEDAEKASRELQAKLEESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQATSANEQND 1456
Query: 133 VTNAIESMKLEIEGSGNILHQHETQ-INKHVEEIRYLQQELKEKENLISELRSVQTSASH 191
++N +ESMK E + +TQ +N E+I Q+ L + N+ E + + H
Sbjct: 1457 LSNIVESMKKSFEEDKIKFIKEKTQEVN---EKILEAQERLNQPSNINMEEIKKKWESEH 1513
Query: 192 RNNSTEELQDL-AVLNKTLK----EQLNYAKELEDMNLKQATE------LKKLRQNNDVQ 240
++++++ L K ++ E++N E + L++ E +K + Q+ ++
Sbjct: 1514 EQEVSQKIREAEEALKKRIRLPTEEKINKIIERKKEELEKEFEEKVEERIKSMEQSGEID 1573
Query: 241 SLLKKENELLQSKLDQLNSLQKKFESLEME-NISLQEKI 278
+L+K+ E +Q+K + LE E N LQE++
Sbjct: 1574 VVLRKQLEA---------KVQEKQKELENEYNKKLQEEL 1603
Score = 56.6 bits (135), Expect = 1e-07
Identities = 102/474 (21%), Positives = 196/474 (40%), Gaps = 85/474 (17%)
Query: 7 IKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENA 66
+ E+ +E + QL+ + L L ++ E + S++ SLQ +++NE + A
Sbjct: 529 VTERLVEFKNIIQLQEKNAELLKVVRNLADKLESKEKKSKQ---SLQKIESETVNEAKEA 585
Query: 67 ---LKDTKILYEENIK-LKEELKS-KDALPKEDEKIITTLRTQVVSLKNEVNLKEQ---- 117
LK K+ E I+ L++EL+ K ++P ED Q+ K ++ + Q
Sbjct: 586 IITLKSEKMDLESRIEELQKELEELKTSVPNEDASYSNVTIKQLTETKRDLESQVQDLQT 645
Query: 118 RIVELAHKLSSKQNEVTNAIE---------SMKLEIEGSGNILHQHETQINKHVEEIR-- 166
RI ++ + + + + I+ S+KL E S IL + ++ + ++
Sbjct: 646 RISQITRESTENMSLLNKEIQDLYDSKSDISIKLGKEKSSRILAEERFKLLSNTLDLTKA 705
Query: 167 ----------YLQQELKEKENLISELRSVQTSASHRNNSTE-------ELQDLAV-LNKT 208
YLQ + ++++ E + S + + E E Q L V L K
Sbjct: 706 ENDQLRKRFDYLQNTILKQDSKTHETLNEYVSCKSKLSIVETELLNLKEEQKLRVHLEKN 765
Query: 209 LKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLN---SLQKKFE 265
LK++LN +D T+L+ L++ + LL++ + Q K+D+L S KK
Sbjct: 766 LKQELNKLSPEKDSLRIMVTQLQTLQKERE--DLLEETRKSCQKKIDELEDALSELKKET 823
Query: 266 SLEMENISLQEKIT----QWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDF 321
S + +I E+ +W +++ K+ VIT ++ Q + L L+ +
Sbjct: 824 SQKDHHIKQLEEDNNSNIEWYQNKIEALKKDYESVITSVDSKQTDIEKLQYKVKSLEKEI 883
Query: 322 NQMSMLNDEMAIERNQLLD-------LNKDYETSILNLKRLNHELEQQKLLSFEECXXXX 374
+ D++ + ++D L K+ E S +NL ++++ K L
Sbjct: 884 EE-----DKIRLHTYNVMDETINDDSLRKELEKSKINLTDAYSQIKEYKDL--------- 929
Query: 375 XXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKI 428
+ Q S + E +K D TN++K L +E + +DKI
Sbjct: 930 ----------YETTSQSLQQTNSKLDESFK----DFTNQIKNLTDEKTSLEDKI 969
>CE06253 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 67.0 bits (162), Expect = 8e-11
Identities = 121/636 (19%), Positives = 267/636 (41%), Gaps = 74/636 (11%)
Query: 42 KLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTL 101
K + E + +SLQ++ + + K+ K+L E N +L ++L++++A + ++ L
Sbjct: 975 KAAKENQIHSLQDEMNSQDETIGKINKEKKLLEENNRQLVDDLQAEEAKQAQANRLRGKL 1034
Query: 102 RTQVVSLKNEVNLKEQRIVELAHKLSSK-------QNEVTNAIESMKLEIEGSGNILHQH 154
+ ++ V +E+RI K K E + + ++KLE + S L +
Sbjct: 1035 EQTLDEMEEAVE-REKRIRAETEKSKRKVEGELKGAQETIDELSAIKLETDAS---LKKK 1090
Query: 155 ETQINK---HVEEIRYLQQEL--KEKEN------LISELRSVQTSASHRNNSTEELQ-DL 202
E I+ +E+ + L L + KEN + EL + S S + + ELQ +L
Sbjct: 1091 EADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQSRSKADRARAELQREL 1150
Query: 203 AVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLL---------KKENELLQSK 253
LN+ L EQ + +D N K+ +E+ K R++ D +++ +K N+ + +
Sbjct: 1151 DELNERLDEQNKQLEIQQDNNKKKDSEIIKFRRDLDEKNMANEDQMAMIRRKNNDQISAL 1210
Query: 254 LDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDT 313
+ L++LQK +E E LQ+++ ++D + K+ + + + ++ + +
Sbjct: 1211 TNTLDALQKSKAKIEKEKGVLQKELDDIN-AQVDQETKSR---VEQERLAKQYEIQVAEL 1266
Query: 314 NSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNH-------ELEQQKLLS 366
K+ Q+ N DL + E ++L +N +L + K +
Sbjct: 1267 QQKVDEQSRQIGEYTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAFSSQLVEAKKAA 1326
Query: 367 FEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSK--- 423
+E DQ + ++E N +D+ +L R+N E+S+
Sbjct: 1327 EDELHERQEFHAACKNLEHEL----DQCH--ELLEEQINGKDDIQRQLSRINSEISQWKA 1380
Query: 424 ---------TDDKIQKRRKITN---DLGISYSQXXXXXXXXXXXXXXXXSATKNHANILE 471
+++ + +RK N DL + S + T++ + ++
Sbjct: 1381 RYEGEGLVGSEELEELKRKQMNRVMDLQEALSAAQNKVISLEKAKGKLLAETEDARSDVD 1440
Query: 472 QKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSVYD 531
+ + + SL++K+ ++ D+ K I+KE A + + + ++ +
Sbjct: 1441 RHLTVIASLEKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTEVFKLRSSMDNLSE 1500
Query: 532 RI---KHDMKLLEKEIFSANKKTTRLKEVFNK--KSLEFIEAVNSLLGFKLEFLAHGKVK 586
+I + + K+ +EI N++ T+ + + KS+ +E L L+ + +
Sbjct: 1501 QIETLRRENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALD-----EAE 1555
Query: 587 LVSCYQPNKYIIADLQSNTLKSDLDKVIPEWETLFQ 622
+ +K + ++ ++S+++K I E E F+
Sbjct: 1556 AALEAEESKVLRLQIEVQQIRSEIEKRIQEKEEEFE 1591
>At1g79280 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2111
Score = 67.0 bits (162), Expect = 8e-11
Identities = 116/576 (20%), Positives = 224/576 (38%), Gaps = 97/576 (16%)
Query: 1 MSLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQ-NKYDKS 59
MS+ + ++ +E L + + LQYK NE + ++ S E + L+ K +S
Sbjct: 963 MSIELRTAKEEIEKLRGEVESSKSHMLQYKSIAQVNETALKQMESAHENFRLEAEKRQRS 1022
Query: 60 MNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRI 119
+ +L++ E + K E + A KED + + ++ SL+ E +K+ +I
Sbjct: 1023 LEAELVSLRERVSELENDCIQKSEQLATAAAGKED--ALLSASAEIASLREENLVKKSQI 1080
Query: 120 VELAHKLSSKQNEVTNAIESMKL---EIEGSGNILHQHETQINKHVEEIRYLQQELKEKE 176
+ ++S+ +N++ E ++ E +L + ++ K + + LQ+E E
Sbjct: 1081 EAMNIQMSTLKNDLETEHEKWRVAQRNYERQVILLSETIQELTKTSQALAALQEEASELR 1140
Query: 177 NLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQN 236
L ++ R ++ S + S E+L L++Q N A+ KK +
Sbjct: 1141 KL-ADARGIENSELNAKWSEEKLM--------LEQQKNLAE-------------KKYHE- 1177
Query: 237 NDVQSLLKKENELLQSKLD--QLNSLQKKFESLEMENISL-QEKITQWGIVRLDGKFKNP 293
L ++N+LL S+L+ LNS +K S + + S + + G+ R+ +
Sbjct: 1178 ------LNEQNKLLHSRLEAKHLNSAEKNSRSGTISSGSTDSDHLEDSGLQRVVHYLRRT 1231
Query: 294 NDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLD----LNKDYETSI 349
++ L R+ L + S L++ + L E A R LL + + S
Sbjct: 1232 KEIAETEISLMRQEKLRLQSQSALKMAESARGSLTAERASTRASLLTDDGIKSLQLQVSE 1291
Query: 350 LNLKR-LNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTE 408
+NL R N +L ++ +FE+C A E ++N +
Sbjct: 1292 MNLLRESNMQLREENKHNFEKCQEMREVAQ----------------KARMESENFENLLK 1335
Query: 409 DLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHAN 468
EL +E+ K + +K ++L +Y
Sbjct: 1336 TKQTELDLCMKEMEKLRMETDLHKKRVDELRETY-------------------------- 1369
Query: 469 ILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRS 528
+ +D+ K + QL + K+ + K LLEK+N +S +E +
Sbjct: 1370 ----RNIDIADYNRLKDEVRQLEEKLKAKDAHAEDCKKVLLEKQNK--ISLLEKE----- 1418
Query: 529 VYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLE 564
K D+ EK + A + ++ FNK+ E
Sbjct: 1419 -LTNCKKDLSEREKRLDDAQQAQATMQSEFNKQKQE 1453
Score = 54.7 bits (130), Expect = 4e-07
Identities = 67/365 (18%), Positives = 156/365 (42%), Gaps = 25/365 (6%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL 67
+ K + + +R+ L LQ + E L++ER + D + L+ +
Sbjct: 1230 RTKEIAETEISLMRQEKLRLQSQSALKMAESARGSLTAERASTRASLLTDDGIKSLQLQV 1289
Query: 68 KDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLS 127
+ +L E N++L+EE K +E ++ R + + +N + K+ + +L K
Sbjct: 1290 SEMNLLRESNMQLREENKHNFEKCQEMREVAQKARMESENFENLLKTKQTEL-DLCMKEM 1348
Query: 128 SKQNEVTNAIESMKLEI-EGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQ 186
K T+ + E+ E NI N+ +E+R L+++LK K+ + + V
Sbjct: 1349 EKLRMETDLHKKRVDELRETYRNI---DIADYNRLKDEVRQLEEKLKAKDAHAEDCKKVL 1405
Query: 187 TSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKE 246
++ + E ++L K L E+ K L+D QAT + N + L+K
Sbjct: 1406 LEKQNKISLLE--KELTNCKKDLSER---EKRLDDAQQAQATMQSEF---NKQKQELEKN 1457
Query: 247 NELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRE 306
++ + +K+ + L +N SL +++ + + + + D + E ++ +RE
Sbjct: 1458 KKIHYTLNMTKRKYEKEKDELSKQNQSLAKQLEE---AKEEAGKRTTTDAVVEQSVKERE 1514
Query: 307 ---------NTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNH 357
+ ++ +++ + ++E+ ER++ + K+ S+ +K+
Sbjct: 1515 EKEKRIQILDKYVHQLKDEVRKKTEDLKKKDEELTKERSERKSVEKEVGDSLTKIKKEKT 1574
Query: 358 ELEQQ 362
+++++
Sbjct: 1575 KVDEE 1579
>Hs4557773 [Z] KOG0161 Myosin class II heavy chain
Length = 1935
Score = 66.6 bits (161), Expect = 1e-10
Identities = 81/361 (22%), Positives = 156/361 (42%), Gaps = 60/361 (16%)
Query: 30 KYTTLQNEYEISKL---SSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKS 86
KY Q+E E S+ S E + L+N Y++S+ LE ++ K L EE L E+L S
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518
Query: 87 KDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQ---NEVTNAIESMKLE 143
E EK+ L + + L++ + E + K+ Q N++ IE E
Sbjct: 1519 SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1578
Query: 144 IEGSGNILHQHETQINKHVE-----EIRYLQQELKEKENLISELRSVQTSASHRNNSTEE 198
+ ++ ++ ++ E R + L+ K+ + +L ++ SH N E
Sbjct: 1579 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 199 LQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQ---SLLKKENELLQSKLD 255
Q K +K + K+ + + L A +R N+D++ +++++ N LLQ++L+
Sbjct: 1639 AQ------KQVKSLQSLLKDTQ-IQLDDA-----VRANDDLKENIAIVERRNNLLQAELE 1686
Query: 256 QLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNS 315
+L ++ ++ E ++ QE I + + +L +NT L++
Sbjct: 1687 ELRAVVEQTE--RSRKLAEQELI----------------ETSERVQLLHSQNTSLINQKK 1728
Query: 316 KLQIDFNQMSMLNDEMAIE-RN--------------QLLDLNKDYETSILNLKRLNHELE 360
K+ D +Q+ +E E RN +L K+ +TS +L+R+ +E
Sbjct: 1729 KMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNME 1787
Query: 361 Q 361
Q
Sbjct: 1788 Q 1788
Score = 50.4 bits (119), Expect = 8e-06
Identities = 69/299 (23%), Positives = 135/299 (45%), Gaps = 21/299 (7%)
Query: 79 KLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIE 138
K+K LKS E EK + +++ + LK + E R EL K+ S E +
Sbjct: 835 KIKPLLKSA-----EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQL 889
Query: 139 SMKLEIEGSGNILHQHETQINKHVE---EIRYLQQELKEKENLISEL----RSVQTSASH 191
++ E + + + + I ++ +++ + + L+++E + +EL R ++ S
Sbjct: 890 QVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE 949
Query: 192 RNNSTEELQ-DLAVLNKTLKEQLNYAKEL-EDMNLKQATELKKLRQNNDVQSLLKKENEL 249
++L+ LA + K N K L E+M K ++ +Q ++ +
Sbjct: 950 LKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDD 1009
Query: 250 LQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLD---GKFKNPNDV-ITELNMLQR 305
LQ++ D++N+L K LE + L+ + Q VR+D K K D+ +T+ +++
Sbjct: 1010 LQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDL 1069
Query: 306 EN-TFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQK 363
EN LD K + DF +++ LN + E+ L K + ++ L ELE ++
Sbjct: 1070 ENDKQQLDERLKKK-DF-ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESER 1126
>At1g73860 [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 987
Score = 66.6 bits (161), Expect = 1e-10
Identities = 68/286 (23%), Positives = 124/286 (42%), Gaps = 37/286 (12%)
Query: 35 QNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKED 94
Q+ EIS L E ET + KY++ +++E+ K K +EE K +EE D L KE+
Sbjct: 230 QHNLEISALKQELET--TKRKYEQQYSQIESQTKTEKSKWEEQKKNEEE--DMDKLLKEN 285
Query: 95 EKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQH 154
++ Q+ +L+ E+ + + ++ S+ T +ES E+E G +++
Sbjct: 286 DQF----NLQISALRQELETTRKAYEQQCSQMESQTMVATTGLESRLKELEQEGKVVNTA 341
Query: 155 ETQINKHVEEIRYLQQELKEKENLISE----LRSVQTSASHRNNSTE----ELQDLAVLN 206
+ + + V+E+ + +E +N + E L+ ++ N S E EL+ V+
Sbjct: 342 KNALEERVKELEQMGKEAHSAKNALEEKIKQLQQMEKETKTANTSLEGKIQELEQNLVMW 401
Query: 207 KTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFES 266
KT ++ E Q K +N Q+LL+ L+ S
Sbjct: 402 KTKVREMEKKSESNHQRWSQKELSYKSFIDNQSQALLE---------------LRSYSRS 446
Query: 267 LEMENISLQEKIT----QWG--IVRLDGKFKNPNDVITELNMLQRE 306
++ E + +QE T Q G ++ L +N + V+TE L E
Sbjct: 447 IKQEILKVQENYTDQFSQLGKKLIELSNAAENYHAVLTENRKLFNE 492
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 66.2 bits (160), Expect = 1e-10
Identities = 75/345 (21%), Positives = 145/345 (41%), Gaps = 59/345 (17%)
Query: 44 SSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL-----------KSKDALPK 92
S E + L+N Y++++++LE ++ K L +E L E++ KS+ +
Sbjct: 1477 SLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIEL 1536
Query: 93 EDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEG-SGNIL 151
E I L +L++E E +I+ + +L+ ++E+ I EIE N
Sbjct: 1537 EKADIQLALEEAEAALEHE----EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQ 1592
Query: 152 HQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKE 211
ET + E+R + ++ K+ + +L ++ SH N E TLK
Sbjct: 1593 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAE---------TLKH 1643
Query: 212 QLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMEN 271
+ +L+D L L+ + +++++ LLQ+++++L + ++ E
Sbjct: 1644 LRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE--RARK 1701
Query: 272 ISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQM-SMLNDE 330
++ QE + D + +L +NT L+ T KL+ D Q+ S + D
Sbjct: 1702 LAEQELL----------------DSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDA 1745
Query: 331 MAIERN--------------QLLDLNKDYETSILNLKRLNHELEQ 361
RN +L K+ +TS +L+R+ LEQ
Sbjct: 1746 SRDARNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNLEQ 1789
Score = 55.1 bits (131), Expect = 3e-07
Identities = 72/363 (19%), Positives = 165/363 (44%), Gaps = 42/363 (11%)
Query: 36 NEYEISKLSSERETYSLQNKYDKSMNELENALKDT--KILYEENIKLKEELKSKDALPKE 93
++ E++ E+E ++ +NK K++ E + L +T K+ E+ + ++ D L E
Sbjct: 956 DDLELTLAKVEKEKHATENKV-KNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE 1014
Query: 94 DEKIITTLRT------QVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGS 147
++K+ + +T QV L++ + +++ V+L + ++ A ES+ L++E
Sbjct: 1015 EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI-LDLE-- 1071
Query: 148 GNILHQHETQINKHVEEIRYLQQELKEKENL-ISELRSVQTSASHRNNSTEELQ-DLAVL 205
N Q + ++ K E LQ ++++++ L + + ++ + EE++ + A
Sbjct: 1072 -NDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATR 1130
Query: 206 NKTLKEQLNYAKELE-----------------DMNLKQATELKKLRQNND---------V 239
KT K++ +YA+ELE ++N K+ E KLR++ + V
Sbjct: 1131 AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMV 1190
Query: 240 QSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITE 299
+L KK + + +Q+++LQ+ + LE E + +I ++ K+ ++
Sbjct: 1191 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLS-SSMESVSKSKANLEKI 1249
Query: 300 LNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHEL 359
L+ + + N ++Q ++++ + E +L ++ E+ + L R
Sbjct: 1250 CRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAF 1309
Query: 360 EQQ 362
QQ
Sbjct: 1310 TQQ 1312
Score = 55.1 bits (131), Expect = 3e-07
Identities = 104/567 (18%), Positives = 215/567 (37%), Gaps = 97/567 (17%)
Query: 41 SKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITT 100
SK + E+ +L+++ ++ + E + L + +L+ E +E E I++
Sbjct: 1242 SKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQ 1301
Query: 101 LRT-------QVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH- 152
L Q LK ++ + + LAH L S +++ E + E EG +
Sbjct: 1302 LSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRA 1361
Query: 153 -------------QHETQINKHVEEIRYLQQELKEK--------ENLISELRSVQTSASH 191
++ET + EE+ Q++L ++ E + ++ S++ +
Sbjct: 1362 LSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQR 1421
Query: 192 RNNSTEELQ-DLAVLNKTL----KEQLNYAKELEDMNLK----QATELKKLRQNNDVQSL 242
E+L D+ N K+Q N+ K L + K QA L+++ + +
Sbjct: 1422 LQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTE 1481
Query: 243 LKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNM 302
L K + LDQL +++++ ++LE E L E+I + G I EL
Sbjct: 1482 LFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENG------------KTIHELEK 1529
Query: 303 LQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQ- 361
R+ L + +L ++ + ++ ++E I R Q L+L + + + E+EQ
Sbjct: 1530 -SRKQIELEKADIQLALEEAEAALEHEEAKILRIQ-LELTQVKSEIDRKIAEKDEEIEQL 1587
Query: 362 ----QKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRL 417
Q+ + + GD + Q + L+ +
Sbjct: 1588 KRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSV 1647
Query: 418 NEELSKT----DDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQK 473
+L T DD ++ + + L I + AN+L+ +
Sbjct: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAI----------------------VERRANLLQAE 1685
Query: 474 ILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSVYDRI 533
+ +L + E+ R +L + LL + E++ LL +N+ L+ ++
Sbjct: 1686 VEELRATLEQTERARKLAEQELLDSN----ERVQLLHTQNTSLI----------HTKKKL 1731
Query: 534 KHDMKLLEKEIFSANKKTTRLKEVFNK 560
+ D+ L+ E+ A++ +E K
Sbjct: 1732 ETDLMQLQSEVEDASRDARNAEEKAKK 1758
Score = 52.0 bits (123), Expect = 3e-06
Identities = 69/305 (22%), Positives = 135/305 (43%), Gaps = 33/305 (10%)
Query: 79 KLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIE 138
K+K LKS E EK + T++ + K+E+ E + EL KL + E +
Sbjct: 836 KIKPLLKSA-----ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKND--- 887
Query: 139 SMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKE-------KENLISEL----RSVQT 187
++L+++ L E + ++ ++ L+ ++KE +E + +EL R ++
Sbjct: 888 -LQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLED 946
Query: 188 SASHRNNSTEELQ-DLAVLNKTLKEQLNYAKEL-EDMNLKQATELKKLRQNNDVQSLLKK 245
S ++L+ LA + K N K L E+++ T K R+ +Q ++
Sbjct: 947 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ 1006
Query: 246 ENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQR 305
+ LQ++ D++NSL K LE + L+ + Q +R+D + +N + +L + Q
Sbjct: 1007 ALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLE-RNKRKLEGDLKLAQE 1065
Query: 306 ENTFLLD-TNSKLQIDFN------QMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHE 358
+LD N K Q+D + L ++ E+ L K + ++ L E
Sbjct: 1066 S---ILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 1122
Query: 359 LEQQK 363
+E ++
Sbjct: 1123 IEAER 1127
>ECU04g1000 [Z] KOG0161 Myosin class II heavy chain
Length = 1700
Score = 66.2 bits (160), Expect = 1e-10
Identities = 82/377 (21%), Positives = 176/377 (45%), Gaps = 37/377 (9%)
Query: 15 LDADQLRRRVLTLQYKYTTLQNEYEISKLSSERE--------TYSLQNKYDKSMNELENA 66
LDA++ RR + K +L+ E + E+ +L+ K D++ ELE A
Sbjct: 860 LDAEKSRREEVEDMLKAMSLKRELLEKSVEDEKRFSMEKDELLMALRYKSDETAQELEKA 919
Query: 67 LKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKL 126
K+ +EE + + +E + I LR +V K ++ +E+ I L ++
Sbjct: 920 RKEVFDGHEERKMWETRVNEVAIQLEEKDSEILRLRREVSEQKGALSQQEKEICSLREEV 979
Query: 127 SSKQNEVTNAIESM----KLEIEGSGNILHQHETQINKHVEEIRYLQQE-------LKEK 175
SK +E +E M E++ + + + ++ + +E ++ +++E LKE
Sbjct: 980 VSKLSEKDAMVEKMLRERDSEVQALKEKVKEKDAEVERILEGMKRMEREGEERNRMLKEN 1039
Query: 176 ENLISELRSVQTSASHRNNSTEEL-QDLAVLNKTLKEQLNYAKELEDMNLKQATELKKL- 233
E+ I ELR+ + + EL +D L K LK+++ ++++ N + E++K+
Sbjct: 1040 ESTIDELRTRCLNMKRWKDEYAELREDYEALQKKLKDEV---EDMQVENDRLHNEIRKIS 1096
Query: 234 RQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKN- 292
++ ++ + KK + L+ + ++ + L+K F+ L E +++ G ++ + +F++
Sbjct: 1097 KEREELGRMQKKLLDDLEFERNRGSKLEKAFQELRGEYEAVE------GQLQKERQFRDS 1150
Query: 293 -PNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQL----LDLNKDYET 347
++ + L+R L + + ++ Q+ DEM E + L LD D E
Sbjct: 1151 TQESLLEKTRGLERRVKSLNEKLRREEMANRQLMSEKDEMYREIHVLQQSKLDEIFDREA 1210
Query: 348 SILNLKRLNHELEQQKL 364
++K+ N ++E Q+L
Sbjct: 1211 GFNSIKK-NLQMEIQRL 1226
>Hs15313972 [Z] KOG0161 Myosin class II heavy chain
Length = 1647
Score = 65.9 bits (159), Expect = 2e-10
Identities = 81/364 (22%), Positives = 164/364 (44%), Gaps = 33/364 (9%)
Query: 14 SLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKIL 73
++D D R+ L+ K + + +L +E ++ S + ++ E E K+TK L
Sbjct: 1104 TVDLDHQRQVASNLEKK------QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKAL 1157
Query: 74 -----YEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLK----EQRIVELAH 124
EE ++ KEE + ++ + D + + + + V +E+ EQ++ E+
Sbjct: 1158 SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1217
Query: 125 KLSSKQNEVTNAIESMKLEIEGSGNILHQH-----ETQINKHVEEIRYLQQELKEKENLI 179
+L ++E+ A E KL +E + + +T+ ++ E+ R L ++++E E +
Sbjct: 1218 QLEELEDEL-QATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL 1276
Query: 180 SELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDV 239
+ R + A E DL K L+ Q+ A + D +KQ +L+ Q D
Sbjct: 1277 EDERKQRALAVASKKKMEI--DL----KDLEAQIEAANKARDEVIKQLRKLQA--QMKDY 1328
Query: 240 QSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITE 299
Q L++ Q +KK +SLE E + LQE++ R + + +++ E
Sbjct: 1329 QRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAE-QERDELADE 1387
Query: 300 LNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHEL 359
+ + LLD +L+ +++ L +E+ E++ + LN + + L + LN EL
Sbjct: 1388 ITNSASGKSALLDEKRRLEA---RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 1444
Query: 360 EQQK 363
++
Sbjct: 1445 AAER 1448
Score = 63.9 bits (154), Expect = 7e-10
Identities = 87/435 (20%), Positives = 178/435 (40%), Gaps = 40/435 (9%)
Query: 7 IKEKPLESLDADQLRRRVLTL-QYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
+K + ++LD ++ + T + + L+ E + E + ++ ++ ++ EL
Sbjct: 822 LKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSE 881
Query: 66 ALKDTKI-----------LYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNL 114
L+ K L +N +L E+K + E E L QV L +V+
Sbjct: 882 QLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSE 941
Query: 115 KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIR-YLQQELK 173
++ VELA K S QNE+ N + ++ E E G + + +++ + LQ+E +
Sbjct: 942 GDRLRVELAEKASKLQNELDN-VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETR 1000
Query: 174 EKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQ-LNYAKELEDMNLKQATELKK 232
+K NL S +R ++ +N+ E+ ++ K L++Q L +L D K +L
Sbjct: 1001 QKLNLSSRIRQLE---EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1057
Query: 233 LRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKN 292
+ + + L K+ E L +L++ ++ LE LQ+++
Sbjct: 1058 IESLEEAKKKLLKDAEALSQRLEE---KALAYDKLEKTKNRLQQEL-------------- 1100
Query: 293 PNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNL 352
+D+ +L+ ++ + L K + ++ A ER++ ++ ET L+L
Sbjct: 1101 -DDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1159
Query: 353 KR-LNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLT 411
R L LE ++ + + + +E Q E++
Sbjct: 1160 ARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE---QQVEEMR 1216
Query: 412 NELKRLNEELSKTDD 426
+L+ L +EL T+D
Sbjct: 1217 TQLEELEDELQATED 1231
Score = 59.7 bits (143), Expect = 1e-08
Identities = 117/595 (19%), Positives = 230/595 (37%), Gaps = 83/595 (13%)
Query: 44 SSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRT 103
+ + E ++ K K ELE + + L EE L E+L+++ L E E+
Sbjct: 527 AKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEE------- 579
Query: 104 QVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVE 163
++ + K+Q + E+ H L S+ E E IL + ++ H++
Sbjct: 580 ----MRARLAAKKQELEEILHDLESRVEEE-----------EERNQILQNEKKKMQAHIQ 624
Query: 164 EIRYLQQELKEKENLISELRSVQTSASHRNNSTEE----LQD---------------LAV 204
+ L+++L E+E +L+ + +A + EE L+D +A
Sbjct: 625 D---LEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 681
Query: 205 LNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL--------DQ 256
+ L E+ AK L + KQ + L + + ++E E + KL DQ
Sbjct: 682 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQ 741
Query: 257 LNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSK 316
+ LQ + + L+++ ++ +E+ Q + R D + + N+ + + LQ + L +
Sbjct: 742 IAELQAQIDELKLQ-LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFES 800
Query: 317 LQIDFN----QMSMLNDEMAIERNQLLD-LNKDYETSILNLKRLNHELEQQKLLSFEECX 371
+ N Q L++E+ + +L D L+ L KR E +K L E
Sbjct: 801 EKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKN 860
Query: 372 XXXXXXXXXXXXXXXXXTPGDQV--------NASNIIEGYKNQTEDLTNELKRLNEELSK 423
+Q+ N +G + ++L E+K L + ++
Sbjct: 861 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAE 920
Query: 424 TDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQ-KILDLTSLKE 482
++ K +K +L S+ + N + +LE+ + + K+
Sbjct: 921 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 980
Query: 483 KKVRILQLRDNPLLKEHYIRKE-----KLALLEKENSDLLSGIETDAIPRSVYDRIKHDM 537
QL+D L + R++ ++ LE+E + L E + R ++ +
Sbjct: 981 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARK---NLEKQV 1037
Query: 538 KLLEKEIFSANKK------TTRLKEVFNKKSLEFIEAVNSLLGFKLEFLAHGKVK 586
L+ ++ KK T E KK L+ EA++ L K LA+ K++
Sbjct: 1038 LALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKA--LAYDKLE 1090
>Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription factor interacts
with stathmin
Length = 1591
Score = 65.5 bits (158), Expect = 2e-10
Identities = 89/383 (23%), Positives = 179/383 (46%), Gaps = 73/383 (19%)
Query: 42 KLSSERETYSLQNKYD-------KSMNELENALKDTKILYEENIKLKEELKSKDALPKED 94
K ++E SL+N+Y+ K E EN +K K E + L+E L++KD +
Sbjct: 860 KEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLK---GELVCLEEVLQNKD----NE 912
Query: 95 EKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQH 154
++ + V+ L+NE K+Q+++E+ + + S+ E+ +S ++ +E + ++
Sbjct: 913 FALVKHEKEAVICLQNE---KDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVEN 969
Query: 155 ETQINKHVEEIRYLQQE-LKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQL 213
+ ++ E++ L+Q LKE E+ + ++R +Q + L++L N+ + Q+
Sbjct: 970 DEKLQLLRAELQSLEQSHLKELEDTL-QVRHIQEFEKVMTDHRVSLEELKKENQQIINQI 1028
Query: 214 NYA---------KELEDMNLK--------------------QATELKKL------RQNND 238
+ K+L+++ LK + E+K L +Q
Sbjct: 1029 QESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKET 1088
Query: 239 VQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVR------LDGKFKN 292
++SLL++E E L++++ +LN QK ++ E + L E T I + L + +
Sbjct: 1089 LKSLLEQETENLRTEISKLN--QKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEE 1146
Query: 293 PNDVI-TELNMLQ--RENTFLLDTNSKLQIDFNQMSMLNDEMAIER---NQLLDLNKDYE 346
++++ ELN + F ++ N K QI Q + ++ A+ER ++ + YE
Sbjct: 1147 ESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYE 1206
Query: 347 TSILNLKRLNHELEQQKLLSFEE 369
I NL E ++QKL+S +E
Sbjct: 1207 AIIQNL-----EKDRQKLVSSQE 1224
>YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC superfamily
Length = 1312
Score = 65.1 bits (157), Expect = 3e-10
Identities = 113/532 (21%), Positives = 223/532 (41%), Gaps = 112/532 (21%)
Query: 19 QLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKY--DKSMNELENALKDTKILYE- 75
+L RR Y T++ + + ++ S E+ L D +++E + L++T++ Y+
Sbjct: 600 ELDRRYTNALYNLNTIEKDLQDNQKSKEKVIQLLSENLPEDCTIDEYNDVLEETELSYKT 659
Query: 76 --ENIKL-----------------------------KEELKSK---DALPKEDEKIITTL 101
EN+K+ E KSK + K D TL
Sbjct: 660 ALENLKMHQTTLEFNRKALEIAERDSCCYLCSRKFENESFKSKLLQELKTKTDANFEKTL 719
Query: 102 RTQVVSLK---NEVNLKEQRIVEL---------AHKLSSKQNEVTNAIESMKLEIEGSGN 149
+ V + K + + L E+ I+ L + K K E T +S E+E
Sbjct: 720 KDTVQNEKEYLHSLRLLEKHIITLNSINEKIDNSQKCLEKAKEETKTSKSKLDELEVDST 779
Query: 150 ILHQH----ETQINKHVEEIRYLQQELKEKEN---LISELRSVQTSASHRNNSTEELQD- 201
L E++I +E+ YL++ELK+ EN ISE S+ ++ + +EL+D
Sbjct: 780 KLKDEKELAESEIRPLIEKFTYLEKELKDLENSSKTISEELSIYNTSEDGIQTVDELRDQ 839
Query: 202 -------LAVLNKTLKE-QLNYAKEL-EDMNLKQATELKKLRQNNDVQSLLKKEN--ELL 250
L L KT+ + Q+ +++ E+ + + K+L + SL +K+N + +
Sbjct: 840 QRKMNDSLRELRKTISDLQMEKDEKVRENSRMINLIKEKELTVSEIESSLTQKQNIDDSI 899
Query: 251 QSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDV--------ITELN- 301
+SK + +N + + + LE ISL+ K + V LD K KN D+ + ++N
Sbjct: 900 RSKRENINDIDSRVKELEARIISLKNKKDEAQSV-LD-KVKNERDIQVRNKQKTVADINR 957
Query: 302 MLQRENTF--------------LLDTNSKLQIDFNQMSMLNDEMAI-------ERNQLLD 340
++ R T L T +L+++ QM L +++ + E+ +L D
Sbjct: 958 LIDRFQTIYNEVVDFEAKGFDELQTTIKELELNKAQMLELKEQLDLKSNEVNEEKRKLAD 1017
Query: 341 LNKDYETSILNLKRLNHELEQQKL---LSFEECXXXXXXXXXXXXXXXXXXTPGDQVNAS 397
N + + NL+ + + + Q + +S + T +++++
Sbjct: 1018 SNNEEKNLKQNLELIELKSQLQHIESEISRLDVQNAEAERDKYQEESLRLRTRFEKLSSE 1077
Query: 398 NI-----IEGYKNQTEDLTNELKRLNEELSKTDDK----IQKRRKITNDLGI 440
N ++ +NQ + LT++L+ +++ K K +Q R +T+D+ +
Sbjct: 1078 NAGKLGEMKQLQNQIDSLTHQLRTDYKDIEKNYHKEWVELQTRSFVTDDIDV 1129
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 65.1 bits (157), Expect = 3e-10
Identities = 124/604 (20%), Positives = 250/604 (40%), Gaps = 90/604 (14%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL 67
+ + LES Q+ + + LQ++ NEY+ + +++N+ ++LE+
Sbjct: 473 QRRNLEST-VSQIEKEKMLLQHRI----NEYQRKAEQENEKRRNVENEVSTLKDQLEDLK 527
Query: 68 K---DTKILYEENIKLKEELKSKDALPKEDEKIITTLR----------TQVVSLKNEVNL 114
K ++++ E+ +L+++L+ + L + + LR +Q+ SL E+
Sbjct: 528 KVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ- 586
Query: 115 KEQRIVELAHKLSSKQNEVTNAI-ESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELK 173
+ RI+E + + K AI E+ + + ++ + +I EE+++L+ L+
Sbjct: 587 ERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLE 646
Query: 174 EKENLISELRSVQT-SASHRNNSTEELQ-DLAVLNKTLKEQLNYAK----ELEDMNLKQA 227
+ E E + + S +NN +L L L + L++++N K L D + Q+
Sbjct: 647 KVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKH--QS 704
Query: 228 TELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLD 287
E K +++ LK+E E + +++ ++K+ L+++ Q+K+ L
Sbjct: 705 IEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEH-----LT 759
Query: 288 GKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEM---AIERNQLLDLNKD 344
G + D + L + +L+ + N+ +L +E+ A E + L L K
Sbjct: 760 GNKERMEDEVKNLTL-------------QLEQESNKRLLLQNELKTQAFEADNLKGLEKQ 806
Query: 345 YETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEG-Y 403
+ I L LE ++LL FE DQ+ A Y
Sbjct: 807 MKQEINTL------LEAKRLLEFELAQLTKQYRGNEGQMRELQ----DQLEAEQYFSTLY 856
Query: 404 KNQTEDLTNELKRLN-EELSKTDDKIQKRRKITNDLGISYSQXXXXXXX--------XXX 454
K Q ++L E++ N E L K + ++ + L ++ ++
Sbjct: 857 KTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFEL 916
Query: 455 XXXXXXSATKNHANILEQ-----KILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALL 509
+A++N I ++ ++ + S+ K + IL+ R+N L E + E+ L
Sbjct: 917 TQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILR-RENEELTEKMKKAEEEYKL 975
Query: 510 EKEN--SDLLSGIE----------TDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEV 557
EKE S+L + E T A+ + + D K+ K+ AN + R KE
Sbjct: 976 EKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKK---ANTQDLRKKEK 1032
Query: 558 FNKK 561
N+K
Sbjct: 1033 ENRK 1036
>SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1727
Score = 64.7 bits (156), Expect = 4e-10
Identities = 126/626 (20%), Positives = 251/626 (39%), Gaps = 109/626 (17%)
Query: 6 QIKEKPLESLDA--DQLRRRVLTLQYKYTTLQN----------EYEISKLSSERETYSLQ 53
Q+ E L+ L+ + ++R TL+ K+T +N E +S L S+ SL+
Sbjct: 875 QMMEIKLQELNGVIELEKQRFSTLEAKFTQQKNTSYSEREALLESSLSDLQSKHT--SLE 932
Query: 54 NKYDKSMNELENALKDTKILYEENIKLKEE-----LKSKDALPKEDEKIITTLRTQVVSL 108
++Y+ S+ +E +K+ E ++K E L++ ++L K KI T+L ++V L
Sbjct: 933 SQYNYSLRNIEQLQAASKLAEEMVERVKTEYDEYRLQTSESLEKNHLKI-TSLEQRIVIL 991
Query: 109 KNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYL 168
++E+ A S++ E NI ET++ +EE ++L
Sbjct: 992 QDEI-----------------------ASSSLRCE-----NITKDSETRVALLLEENKHL 1023
Query: 169 QQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQAT 228
EL +SHRN + L+ K+QL E D+ +
Sbjct: 1024 NNEL----------------SSHRNAEKQHLEK----ENDYKQQLLLVTE--DLRKTRED 1061
Query: 229 ELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDG 288
K+L ++ D +S L+K E L+Q+ L K+ I+L+ I + +
Sbjct: 1062 YEKELLRHADARSTLQKLREDYTKALEQVEDLNKE--------IALKAGINESQPFPISE 1113
Query: 289 KFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEM-AIERNQLLDLNK---- 343
K + + E+ +L+++N LL ++F +++ + ++ ++ + L DL
Sbjct: 1114 K---EDPLRQEVYVLKKQNAMLLTQLQSSNLNFAEITSPSPDLDSVMKLGLSDLQNHVKR 1170
Query: 344 -DYETSILNLKRLNHELEQQKLL----SFEECXXXXXXXXXXXXXXXXXXTPGDQVNASN 398
E I++ +R LE +KL S + G++ N N
Sbjct: 1171 ISKEMEIISCQRQLLFLENKKLKRTVESSNRVIADLQRGITEKDVSSTSESVGERSNYLN 1230
Query: 399 IIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXX 458
++ + L L+R E +++ +KI+ + + ++ Q
Sbjct: 1231 MVALLNESNKSLRENLERNEEVITELREKIETLKTDLANFRLNKEQLESQLQTEKAAVKK 1290
Query: 459 XXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLS 518
++ + + ++ +L L S +L++ + KE+ I + L +E L S
Sbjct: 1291 LENSNEEYKRHNQEILLSLNSSTSTSSDASRLKNELVSKENLIEE-----LNQEIGHLKS 1345
Query: 519 GIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFN-------KKSLEFIEAVNS 571
+ET +S + ++++ + +I K T+L + KSLE +
Sbjct: 1346 ELET---VKSKSEDLENERAQNQSKIEQLELKNTKLAAAWRTKYEQVVNKSLEKHNQIRQ 1402
Query: 572 LLGFKLEFLAHGKVKLVSCYQPNKYI 597
L K L + K+ C+Q N+ +
Sbjct: 1403 QLSQKTSEL---EAKVAECHQLNEQL 1425
Score = 62.0 bits (149), Expect = 3e-09
Identities = 88/459 (19%), Positives = 189/459 (41%), Gaps = 63/459 (13%)
Query: 17 ADQLRRRVLTLQYKYTTLQNEY-----EISK-----LSSERETYSLQNKYDKSMNELENA 66
+ +L+ V LQ K T+ Q+ Y E++ L SE LQ KYD ++EL+
Sbjct: 295 SSELQSEVAALQEKLTSQQSLYNNVTEELNNNKQQLLISENSLRELQEKYDSVVSELQVV 354
Query: 67 LKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKL 126
++ + L L K + + E T + + + L+ +V+ + ++ L +K
Sbjct: 355 KENKNTSVSAGVGLFSPLAQKLSAVQNPEFSFTKVYSDNMKLQQKVSSLKLQLDRLTNKF 414
Query: 127 SSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQ 186
SS +V I +K Q ++I ++ + +L + L+ N ++++++
Sbjct: 415 SSFCEQVKQRIPVVK-----------QQRSEIVRNNIYMNFLSESLETSNNNLTKVQAEL 463
Query: 187 TSASHRNN--------STEELQDLAVLNKTLKEQLNYAKELEDMNLKQATE--LKKLRQN 236
S R S + DL+ L +L++ E + N+ + L + QN
Sbjct: 464 LSTKMRQEACYLQLTASRTQCSDLSREVICLMAELDHLNETKSRNVPATVQVALDEYAQN 523
Query: 237 NDVQSLLKKENEL-----LQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFK 291
S EL ++ + + L++K +LE + + +Q++ Q+ I + +
Sbjct: 524 PSTASETLVNKELANFSSIKEAVSKTLELREKVRALECD-VEIQKQTVQYQI--SNAVKE 580
Query: 292 NPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLN--------- 342
N N + ++ L+ E L + K + N+ ++L + +A R+ +L N
Sbjct: 581 NSNTLSEQIKNLESE---LNSSKIKNESLLNERNLLKEMLATSRSSILSHNSSAGNIDDK 637
Query: 343 -KDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQ-------- 393
K + S L++ N+E+ + ++ + +E +
Sbjct: 638 MKSIDESTRELEK-NYEVYRNEMTAIQESLSKRNQDLLSEMEAIRKELENSKYQQQLSTD 696
Query: 394 --VNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQK 430
NA+N +E +K + ++L + + L + +S+ D + K
Sbjct: 697 RLTNANNDVEAFKKEAKELRSINQNLQDIISRQDQRASK 735
Score = 53.9 bits (128), Expect = 7e-07
Identities = 79/376 (21%), Positives = 158/376 (42%), Gaps = 47/376 (12%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALK 68
++ L L+ +L+R V + LQ +SS E S+ E N L
Sbjct: 1181 QRQLLFLENKKLKRTVESSNRVIADLQRGITEKDVSSTSE----------SVGERSNYLN 1230
Query: 69 DTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLK-NEVNLKEQRIVELA--HK 125
+L E N L+E L+ + + E + I TL+T + + + N+ L+ Q E A K
Sbjct: 1231 MVALLNESNKSLRENLERNEEVITELREKIETLKTDLANFRLNKEQLESQLQTEKAAVKK 1290
Query: 126 LSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRS- 184
L + E + + L + S + L+ EL KENLI EL
Sbjct: 1291 LENSNEEYKRHNQEILLSLNSS-----------TSTSSDASRLKNELVSKENLIEELNQE 1339
Query: 185 ---VQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATEL-------KKLR 234
+++ + +E+L++ N++ EQL EL++ L A K L
Sbjct: 1340 IGHLKSELETVKSKSEDLENERAQNQSKIEQL----ELKNTKLAAAWRTKYEQVVNKSLE 1395
Query: 235 QNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPN 294
++N ++ L ++ L++K+ + + L ++ + + ++ V L+ +F +
Sbjct: 1396 KHNQIRQQLSQKTSELEAKVAECHQLNEQLNKPSATPTATTQ--SEPSTVSLE-EFNSTK 1452
Query: 295 DVITELNMLQRENTFLLDTN----SKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSIL 350
+ ++ E +L+T K++ + N+ + + I + ++ K + +L
Sbjct: 1453 EELSSTQRKLSEIMDILNTTKEELEKVRQNSNKSEGTSKDTEIPNEEEMERKKVMQQEVL 1512
Query: 351 NLK-RLNHELEQQKLL 365
L+ R+ EL++ +LL
Sbjct: 1513 RLRSRIAKELQKNELL 1528
Score = 53.1 bits (126), Expect = 1e-06
Identities = 78/378 (20%), Positives = 158/378 (41%), Gaps = 62/378 (16%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
+++EK +E+L D R+ Q + + + KL + E Y N+ E+
Sbjct: 1255 ELREK-IETLKTDLANFRLNKEQLESQLQTEKAAVKKLENSNEEYKRHNQ------EILL 1307
Query: 66 ALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHK 125
+L + + +LK EL SK E +I L ++ LK+E+ + + +L ++
Sbjct: 1308 SLNSSTSTSSDASRLKNELVSK-------ENLIEELNQEIGHLKSELETVKSKSEDLENE 1360
Query: 126 LSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEK----ENLISE 181
+ Q+++ +E ++ + ++E +NK +E+ ++Q+L +K E ++E
Sbjct: 1361 RAQNQSKIEQ-LELKNTKLAAAWRT--KYEQVVNKSLEKHNQIRQQLSQKTSELEAKVAE 1417
Query: 182 LRSVQ----------TSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELK 231
+ T+ + ST L++ + L E+ D+ EL+
Sbjct: 1418 CHQLNEQLNKPSATPTATTQSEPSTVSLEEFNSTKEELSSTQRKLSEIMDILNTTKEELE 1477
Query: 232 KLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFK 291
K+RQN++ K+ E+ + EME ++K+ Q ++RL +
Sbjct: 1478 KVRQNSNKSEGTSKDTEIPNEE--------------EME----RKKVMQQEVLRLRSRIA 1519
Query: 292 NPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILN 351
+ + +L+++N L D Q+ Q ++++ E A + D KD E N
Sbjct: 1520 KE---LQKNELLRKQNQVLQD-----QVKALQETVVSSEEAESASVHAD-TKDLE----N 1566
Query: 352 LKRLNHELEQQKLLSFEE 369
LK+ L + F E
Sbjct: 1567 LKKTEEMLSVTFQVIFNE 1584
>Hs20542063 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 64.3 bits (155), Expect = 5e-10
Identities = 79/361 (21%), Positives = 153/361 (41%), Gaps = 60/361 (16%)
Query: 30 KYTTLQNEYEISKL---SSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKS 86
KY Q+E E S+ S E + L+N Y++S+ LE ++ K L EE L E+L
Sbjct: 1461 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGE 1520
Query: 87 KDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEG 146
E EK+ L + + L++ + E + K+ Q E ++ ++
Sbjct: 1521 GGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1580
Query: 147 SGNILHQHETQINKHVE--------EIRYLQQELKEKENLISELRSVQTSASHRNNSTEE 198
+ Q + + V+ E R + L+ K+ + +L ++ SH N E
Sbjct: 1581 KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAE 1640
Query: 199 LQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQ---SLLKKENELLQSKLD 255
Q K +K + K+ + + L A +R N+D++ +++++ N LLQ++L+
Sbjct: 1641 AQ------KQVKSLQSLLKDTQ-IQLDDA-----VRANDDLKENIAIVERRNNLLQAELE 1688
Query: 256 QLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNS 315
+L ++ ++ E ++ QE I + + +L +NT L++
Sbjct: 1689 ELRAVVEQTE--RSRKLAEQELI----------------ETSERVQLLHSQNTSLINQKK 1730
Query: 316 KLQIDFNQMSMLNDEMAIE-RN--------------QLLDLNKDYETSILNLKRLNHELE 360
K++ D Q+ +E E RN +L K+ +TS +L+R+ +E
Sbjct: 1731 KMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNME 1789
Query: 361 Q 361
Q
Sbjct: 1790 Q 1790
Score = 58.2 bits (139), Expect = 4e-08
Identities = 71/304 (23%), Positives = 139/304 (45%), Gaps = 31/304 (10%)
Query: 79 KLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIE 138
K+K LKS E EK + T++ + +K + E R EL K+ S E +
Sbjct: 837 KIKPLLKSA-----ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKND--- 888
Query: 139 SMKLEIEGSGNILHQHETQINKHVE-------EIRYLQQELKEKENLISEL----RSVQT 187
++L+++ + L+ E + ++ ++ +++ + + L+++E + +EL R ++
Sbjct: 889 -LQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED 947
Query: 188 SASHRNNSTEELQ-DLAVLNKTLKEQLNYAKEL-EDMNLKQATELKKLRQNNDVQSLLKK 245
S ++L+ LA + K N K L E+M K ++ +Q ++
Sbjct: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 246 ENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLD---GKFKNPNDV-ITELN 301
+ LQ + D++NSL K LE + L+ + Q VR+D K K D+ +T+ +
Sbjct: 1008 ALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1067
Query: 302 MLQRENTFLL--DTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHEL 359
++ EN L + K + D NQ N ++ E+ L L K + + ++ L EL
Sbjct: 1068 IMDLENDKLQLEEKLKKKEFDINQQ---NSKIEDEQVLALQLQKKLKENQARIEELEEEL 1124
Query: 360 EQQK 363
E ++
Sbjct: 1125 EAER 1128
>Hs20558376 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 63.9 bits (154), Expect = 7e-10
Identities = 82/362 (22%), Positives = 154/362 (41%), Gaps = 62/362 (17%)
Query: 30 KYTTLQNEYEISKLSSER---ETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL-- 84
KY Q E E S+ S E + ++N Y++S+++LE ++ K L +E L E++
Sbjct: 1462 KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1521
Query: 85 ---------KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTN 135
K K + +E +I L SL++E E +I+ + +L+ ++EV
Sbjct: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHE----EGKILRIQLELNQVKSEVDR 1577
Query: 136 AIESMKLEIEG-SGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNN 194
I EI+ N ET + EIR L+ K+ + +L ++ +H N
Sbjct: 1578 KIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637
Query: 195 STEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL 254
E +L+ N L++ L L+ + +++++ LLQ+++
Sbjct: 1638 LAAE---------SLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 255 DQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTN 314
++L + ++ E I+ QE + D + +L +NT L++T
Sbjct: 1689 EELWATLEQTE--RSRKIAEQELL----------------DASERVQLLHTQNTSLINTK 1730
Query: 315 SKLQIDFNQMSMLNDEMAIE-RN--------------QLLDLNKDYETSILNLKRLNHEL 359
KL+ D +Q+ +E+ E RN +L K+ +TS +L+R+ L
Sbjct: 1731 KKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNL 1789
Query: 360 EQ 361
EQ
Sbjct: 1790 EQ 1791
Score = 60.8 bits (146), Expect = 6e-09
Identities = 118/601 (19%), Positives = 225/601 (36%), Gaps = 109/601 (18%)
Query: 18 DQLRRRVLTLQYKYTTLQNEYEISKLSSERETYS-LQNKYDKSMNELENALKDTKILYEE 76
D L+R L+ + + L+ E + LSS E S + +K LE+ + + K EE
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETD--DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEE 1268
Query: 77 NIKL------------------KEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQR 118
+L +L KDAL + + Q+ LK+++ + +
Sbjct: 1269 QQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKA 1328
Query: 119 IVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH--------------QHETQINKHVEE 164
LAH L S +++ E + E EG + ++ET + EE
Sbjct: 1329 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE 1388
Query: 165 I----RYLQQELKEKENLI----SELRSVQTSASHRNNSTEELQ-DLAVLNKTL----KE 211
+ + L Q L+E E + ++ S++ + N E+L D+ N K+
Sbjct: 1389 LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKK 1448
Query: 212 QLNYAKELEDMNLK----QATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL 267
Q N+ K L + K QA +++ + + L K + + LDQL +L+++ ++L
Sbjct: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNL 1508
Query: 268 EMENISLQEKITQWG--IVRLDGKFKNPNDVITELNMLQRENTFLLDTNS----KLQIDF 321
+ E L E+I + G I L+ K E+ E L+ ++Q++
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 322 NQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXX 381
NQ+ D E+++ +D K T ++ + + E
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE--------------------- 1607
Query: 382 XXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGI- 440
+ D + +EG N+ E N RL E R N GI
Sbjct: 1608 -----IRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE---------SLRNYRNTQGIL 1653
Query: 441 -SYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEH 499
+ + AN+L+ +I +L + E+ R ++ + LL
Sbjct: 1654 KETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLD-- 1711
Query: 500 YIRKEKLALLEKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFN 559
E++ LL +N+ L+ + ++++D+ L+ E+ +++ +E
Sbjct: 1712 --ASERVQLLHTQNTSLI----------NTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1759
Query: 560 K 560
K
Sbjct: 1760 K 1760
>Hs13124877 [Z] KOG0161 Myosin class II heavy chain
Length = 1266
Score = 63.9 bits (154), Expect = 7e-10
Identities = 73/310 (23%), Positives = 145/310 (46%), Gaps = 39/310 (12%)
Query: 9 EKPLESLDA--DQLRRRVLTLQYKYTTLQNEYEI-----SKLSSERE---------TYSL 52
E+ LE +A +L+ +T + K L++E + +KLS ER+ T +L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL 1015
Query: 53 QNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKI----------ITTLR 102
+ +K+ N + K ++ E ++LK+E KS+ L K K+ I L+
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 103 TQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHV 162
Q+ LK ++ KE+ + +L + + NA++ ++ E+EG H + + + +
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEG-------HISDLQEDL 1127
Query: 163 EEIRYLQQEL-KEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELED 221
+ R + + K+K +L EL +++T +ST Q+L K +E K L++
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA--KREQEVTVLKKALDE 1185
Query: 222 MNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQW 281
+++++RQ + Q++ + +L Q K + N L K ++LE EN L ++
Sbjct: 1186 ETRSHEAQVQEMRQKH-AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVL 1243
Query: 282 GIVRLDGKFK 291
G + + + K
Sbjct: 1244 GQAKQEVEHK 1253
Score = 58.2 bits (139), Expect = 4e-08
Identities = 86/420 (20%), Positives = 167/420 (39%), Gaps = 45/420 (10%)
Query: 33 TLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPK 92
T Q E +K ++T Q K + + ELE K +++ E+N+ L+E+L+++ L
Sbjct: 848 TRQEEEMQAKEDELQKTKERQQKAENELKELEQ--KHSQLTEEKNL-LQEQLQAETELYA 904
Query: 93 EDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH 152
E E++ L K+Q + E+ H++ ++ E + + ++ E + +
Sbjct: 905 EAEEMRVRLAA-----------KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 153 QHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDL-----AVLNK 207
E Q+ + + LQ E E I +L +NN + + L + L
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 208 TLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL--------DQLNS 259
L E+ AK L + K + + +L + ++E E L+ KL +Q+
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
Query: 260 LQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQI 319
LQ + L+M+ ++ +E+ Q + RLD + N+ + ++ L+ S LQ
Sbjct: 1074 LQAQIAELKMQ-LAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-------ISDLQE 1125
Query: 320 DFNQMSMLNDEMAIERNQLLDLNKDYETSILNLK-RLNHELEQQKLLSFEECXXXXXXXX 378
D + ++ Q DL ++ E L+ L+ QQ+L + E
Sbjct: 1126 DLDSERAARNK---AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE------QEV 1176
Query: 379 XXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDL 438
T + + + + E+LT +L++ + D Q K DL
Sbjct: 1177 TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1236
Score = 55.1 bits (131), Expect = 3e-07
Identities = 59/311 (18%), Positives = 131/311 (41%), Gaps = 51/311 (16%)
Query: 16 DADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQ---NKYDKSMNELENALKDTKI 72
+A+++R R+ + + + +E E E LQ K + M +LE L++ +
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 73 LYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNE 132
+ KL+ E + +A K+ E I + Q L E L E+RI +L L+ ++ +
Sbjct: 965 ARQ---KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Query: 133 VTNA---------------------------IESMKLEIEGSGNILHQHETQINKHVEEI 165
N +E +K ++EG + H+ + + E+
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081
Query: 166 RYLQQELKEKENLISELRSVQTSASHRNNSTEELQDL---------------AVLNKTLK 210
+ Q K++E L + L + + +NN+ +++++L A NK K
Sbjct: 1082 K--MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Query: 211 EQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLD-QLNSLQKKFESLEM 269
++ + +ELE + + L ++++ ++E +L+ LD + S + + + +
Sbjct: 1140 QKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ 1199
Query: 270 ENISLQEKITQ 280
++ E++T+
Sbjct: 1200 KHAQAVEELTE 1210
>CE20196 [Z] KOG0161 Myosin class II heavy chain
Length = 1413
Score = 63.9 bits (154), Expect = 7e-10
Identities = 119/510 (23%), Positives = 203/510 (39%), Gaps = 77/510 (15%)
Query: 30 KYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDA 89
+Y+ L E SK +SE+E +L + D + + A+ TK+ + + + E K +
Sbjct: 652 RYSLLMKNKEQSKGASEKEKCTLICQ-DAQVRKERYAVGKTKLFCKVGVISELETKRNNY 710
Query: 90 LPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGN 149
+ I ++ + L + +L E+R KL + N + +L
Sbjct: 711 I----SSFIILIQANIRYLNIQKDLIERR-----KKLEAVVTIQDNVRQFAELSQWPWYR 761
Query: 150 ILHQHETQI--NKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNK 207
I H I N+ E I L+ E + E I E+ A N L+ +L++
Sbjct: 762 IYHLTRGLIPRNRDKERIEELENEKLKLEEEIQEMEIKNEEALKEN-----LKLSMLLDR 816
Query: 208 TLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL 267
E++ KELE++ KQ E LL+KE E ++ ++++ ++ F L
Sbjct: 817 EKSEKVKVQKELEEVE-KQGRE-----------KLLEKEREFRKT-MEEMEQNEEIFNVL 863
Query: 268 EMENISLQEKITQWGIVRLDGKFKNPNDVITELNM----LQRENTFLLDTN-------SK 316
E + +K+ + V + + K I +LNM L+ EN L +T S
Sbjct: 864 ERKYNEQHKKVMKMNDVLREYERK-----IEQLNMEKTDLENENQKLRETQNRQDSHYSN 918
Query: 317 LQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXX 376
L+ + + S L DE+ +NQ+ L+ + L + +L LE +K +
Sbjct: 919 LEKEVMEKSSLIDEL---QNQIQKLSDENNEQRLTIAKLETALEDEKARFARQNNTIGDM 975
Query: 377 XXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITN 436
NI +N T + E ++LNEEL+ + IQK+ K +
Sbjct: 976 QKLISELNEKIA------RFDNIALNERNSTRKIEREKEKLNEELTTAKEIIQKQAKKID 1029
Query: 437 DLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLL 496
+L KN A+ LE+K+ D ++ V+ L+ L
Sbjct: 1030 EL------------------KEECRKRKNEASRLERKLEDKEAMMADCVKELKDSHKERL 1071
Query: 497 KEHYIR----KEKLALLEKENSDLLSGIET 522
KE + K K + LE ENS S IET
Sbjct: 1072 KEMEQKVEDVKRKNSKLENENSTQKSQIET 1101
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 63.5 bits (153), Expect = 9e-10
Identities = 76/362 (20%), Positives = 152/362 (40%), Gaps = 62/362 (17%)
Query: 30 KYTTLQNEYEISKLSSER---ETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL-- 84
KY Q E E S+ S E + ++N Y++S++ LE ++ K L +E L E++
Sbjct: 1463 KYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAE 1522
Query: 85 ---------KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTN 135
K K L E ++ T+L SL++E E +I+ + +L+ ++E+
Sbjct: 1523 GGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHE----EGKILRIQLELNQVKSEIDR 1578
Query: 136 AIESMKLEIEG-SGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNN 194
I E++ N L E+ + EIR L+ K+ + +L ++ +H N
Sbjct: 1579 KIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANR 1638
Query: 195 STEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL 254
E L+ N L+D L ++ + +++++ L+Q+++
Sbjct: 1639 QAAE---------ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEV 1689
Query: 255 DQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTN 314
++L + +E K+ + ++ D + +L +NT L++T
Sbjct: 1690 EELRA--------SLERTERGRKMAEQELL----------DASERVQLLHTQNTSLINTK 1731
Query: 315 SKLQIDFNQM-SMLNDEMAIERN--------------QLLDLNKDYETSILNLKRLNHEL 359
KL+ D +Q+ + D + RN +L K+ +TS +L+R+ +
Sbjct: 1732 KKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNM 1790
Query: 360 EQ 361
EQ
Sbjct: 1791 EQ 1792
Score = 59.3 bits (142), Expect = 2e-08
Identities = 118/599 (19%), Positives = 235/599 (38%), Gaps = 107/599 (17%)
Query: 19 QLRRRVLTLQYKYTTLQNE-----YEISKLSSERETYS-LQNKYDKSMNELENALKDTKI 72
+L +++ +LQ L+ E EI+ L+S ET S + ++K LE+ L + K
Sbjct: 1206 ELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKT 1265
Query: 73 LYEENIKLKEELKS------------------KDALPKEDEKIITTLRTQVVSLKNEVNL 114
EE +L EL + KDA+ + + Q+ LK ++
Sbjct: 1266 KEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEE 1325
Query: 115 KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH--------------QHETQINK 160
+ + LAH L S +++ E + E E + ++ET +
Sbjct: 1326 ETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQ 1385
Query: 161 HVEEIRYLQQELKEK--------ENLISELRSVQTSASHRNNSTEELQ-DLAVLNKTL-- 209
EE+ +++L ++ E + S+ S++ + N E+L D+ N
Sbjct: 1386 RTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIA 1445
Query: 210 --KEQLNYAKELEDMNLK----QATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKK 263
K+Q N+ K L + K QA +++ + + L K + LD L +L+++
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE 1505
Query: 264 FESLEMENISLQEKITQWG--IVRLDGKFKNPNDVITELNMLQRENTFLLDTNS----KL 317
++L+ E L E+I + G I L+ K + +EL E L+ ++
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565
Query: 318 QIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXX 377
Q++ NQ+ D E+++ LD LKR NH + + S
Sbjct: 1566 QLELNQVKSEIDRKIAEKDEELD----------QLKR-NHLRVVESMQS----------- 1603
Query: 378 XXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITND 437
+ D + +EG N+ E +L N + ++ ++ + I D
Sbjct: 1604 ----TLDAEIRSRNDALRIKKKMEGDLNEME---IQLNHANRQAAEALRNLRNTQGILKD 1656
Query: 438 LGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLK 497
+ + + AN+++ ++ +L + E+ R ++ + LL
Sbjct: 1657 TQLHLDD----AIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLD 1712
Query: 498 EHYIRKEKLALLEKENSDLLS---GIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTR 553
E++ LL +N+ L++ +ETD +I+ +M+ + +E +A +K +
Sbjct: 1713 ----ASERVQLLHTQNTSLINTKKKLETD------ISQIQGEMEDIVQEARNAEEKAKK 1761
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 63.2 bits (152), Expect = 1e-09
Identities = 73/345 (21%), Positives = 146/345 (42%), Gaps = 59/345 (17%)
Query: 44 SSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL-----------KSKDALPK 92
S E + ++N Y++S+++LE ++ K L +E L E++ K K + +
Sbjct: 1480 SLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQ 1539
Query: 93 EDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEG-SGNIL 151
E ++ L SL++E E +I+ + +L+ ++EV I EI+ N +
Sbjct: 1540 EKSELQAALEEAEASLEHE----EGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHI 1595
Query: 152 HQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKE 211
E+ + EIR ++ K+ + +L ++ +H N E L+
Sbjct: 1596 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE---------ALRN 1646
Query: 212 QLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMEN 271
N L+D L L+ + +++++ LLQ+++++L + ++ E
Sbjct: 1647 YRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE--RSRK 1704
Query: 272 ISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQM-SMLNDE 330
I+ QE + D + +L +NT L++T KL+ D +Q+ + D
Sbjct: 1705 IAEQELL----------------DASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDI 1748
Query: 331 MAIERN--------------QLLDLNKDYETSILNLKRLNHELEQ 361
+ RN +L K+ +TS +L+R+ LEQ
Sbjct: 1749 IQEARNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNLEQ 1792
Score = 60.8 bits (146), Expect = 6e-09
Identities = 129/604 (21%), Positives = 232/604 (38%), Gaps = 92/604 (15%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALK 68
EK E L + +R+ L+ K TL E +L + E SL + ++ + L
Sbjct: 861 EKTKEELAKTEAKRK--ELEEKMVTLMQEKNDLQLQVQAEADSLADAEERC-----DQLI 913
Query: 69 DTKILYEENIK-LKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLS 127
TKI E IK + E + ++ + E L + LK +++ E + ++ +
Sbjct: 914 KTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 973
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQT 187
+ +N+V N E M E + + + H + + LQ E ++K N +++ +
Sbjct: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE-EDKVNTLTKAKI--- 1029
Query: 188 SASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKEN 247
++L+ K ++ L AK + +LK A E + ND Q L +
Sbjct: 1030 ---KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQE-SAMDIENDKQQL----D 1081
Query: 248 ELLQSKLDQLNSLQKKFESLEMENISLQEKI--TQWGIVRLDGKF-----------KNPN 294
E L+ K +++ LQ K E + + LQ+KI Q I L+ + K +
Sbjct: 1082 EKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 295 DVITELNMLQRE-------NTFLLDTNSKLQIDFNQMSMLNDEMAIE--------RNQLL 339
D+ EL + + ++ N K + +F +M +E ++ R +
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201
Query: 340 DLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNI 399
D + I NL+R+ +LE++K E A
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS-------------KAKGN 1248
Query: 400 IEGYKNQTEDLTNELKRLNEELSK-TDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXX 458
+E ED +E+K EE + +D +R ++ + G YS+
Sbjct: 1249 LEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG-EYSRQLDEKDTLVSQLSR 1307
Query: 459 XXSATKNHANILEQKILDLTSLKEKKVRILQ--LRDNPLLKEHY-----IRKEKLALLEK 511
A L++++ + K LQ D LL+E Y + E + K
Sbjct: 1308 GKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSK 1367
Query: 512 ENSDLL---SGIETDAIPRSVYDRIKHDMKLLEKEIFSANKK-TTRLKEVFNKKSLEFIE 567
NS++ + ETDAI R+ +E+ A KK RL++ + E +E
Sbjct: 1368 ANSEVAQWRTKYETDAIQRT-------------EELEEAKKKLAQRLQD-----AEEHVE 1409
Query: 568 AVNS 571
AVN+
Sbjct: 1410 AVNA 1413
>Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 636
Score = 63.2 bits (152), Expect = 1e-09
Identities = 81/347 (23%), Positives = 139/347 (39%), Gaps = 54/347 (15%)
Query: 3 LTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNE 62
L Q++E + D R++ + + TLQ E E +E + E
Sbjct: 121 LEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERE----DLNKELVQASERLKNQSKE 176
Query: 63 LENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVEL 122
L++A K+ +E +++ E L T L TQ L V KE+ + +
Sbjct: 177 LKDAHCQRKLAMQEFMEINERL--------------TELHTQKQKLARHVRDKEEEVDLV 222
Query: 123 AHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISEL 182
K+ S + E+ E K E+E L ++ K E+ + ++L EN + L
Sbjct: 223 MQKVESLRQELRRT-ERAKKELEVHTEALAAEASKDRKLREQSEHYSKQL---ENELEGL 278
Query: 183 RSVQTSASHRNNSTEELQDLAVLNKTL-KEQLNYAKELEDMNLKQATELKKLRQ----NN 237
+ Q S S S E Q++ L L K+ + Y +EL A E+K L++ +
Sbjct: 279 KQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSE 338
Query: 238 DVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVI 297
Q L KE +L+ KL E E+ S +E+ + +FK
Sbjct: 339 GQQLALNKEIMILKDKL----------EKTRRESQSEREEF--------ESEFKQ----- 375
Query: 298 TELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKD 344
+RE L + N KL + ++++ L + ++I QL + KD
Sbjct: 376 ----QYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKD 418
>SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1044
Score = 62.8 bits (151), Expect = 2e-09
Identities = 80/375 (21%), Positives = 162/375 (42%), Gaps = 47/375 (12%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTT-----LQNEYEISKLSSERETYSLQNKYDKSM 60
Q+ EK E L +Q + L ++ YT ++ E ++ + E E ++ K
Sbjct: 652 QLAEKYHEELLDNQQKLYDLRIELDYTKSNCKQMEEEMQVLREGHESEIKDFIEEHSKLT 711
Query: 61 NELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIV 120
+L++ I+ +N L EL+ +L + L ++ L+N++NL
Sbjct: 712 KQLDDIKNQFGIISSKNRDLLSELEKSKSLNNS----LAALESKNKKLENDLNL------ 761
Query: 121 ELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLIS 180
L+ K N+ ES K I E +++K + L L KEN+IS
Sbjct: 762 -----LTEKLNKKNADTESFKNTI---------REAELSK-----KALNDNLGNKENIIS 802
Query: 181 ELRSVQTSASHR-----NNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQ 235
+L++ + S R + ++ + LN+ + + +E +N QA ELK +Q
Sbjct: 803 DLKNKLSEESTRLQELQSQLNQDKNQIETLNERISAAADELSSMESINKNQANELKLAKQ 862
Query: 236 N-NDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPN 294
+++Q + N+L + ++++SL+K E+ +L +++ K + +
Sbjct: 863 KCSNLQEKINFGNKLAKEHTEKISSLEKDLEAATKTASTLSKELKTVKSENDSLKSVSND 922
Query: 295 DVITELNM----LQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLN--KDYET- 347
D E ++ + + L + N KL ++ L ++ +N L++ KD +
Sbjct: 923 DQNKEKSVNNEKFKEVSQALAEANEKLNARDEEIERLKVDIIGLQNASLNMQSLKDSDNR 982
Query: 348 SILNLKRLNHELEQQ 362
+I +L+ N ELE++
Sbjct: 983 TISDLESKNKELEKK 997
Score = 60.1 bits (144), Expect = 1e-08
Identities = 95/432 (21%), Positives = 179/432 (40%), Gaps = 76/432 (17%)
Query: 20 LRRRVLTLQYKYTTLQNEYEISKLSSERETY--SLQNKYDKSMNELENALKDTKILYEEN 77
++R V + + N YEI+ LS +++ SL+ + D + L+ ++K+ I E
Sbjct: 577 VKRDVFINRLQRLRRMNLYEITFLSMKQKMQLKSLREEIDNTKEALDLSVKERSIQEE-- 634
Query: 78 IKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAI 137
KL E LK+ +E ++ ++ L N+ L + RI K + KQ E
Sbjct: 635 -KLNESLKTSKTNLEEQTQLAEKYHEEL--LDNQQKLYDLRIELDYTKSNCKQME----- 686
Query: 138 ESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTE 197
E M++ EG HE++I +EE L ++L + +N + S
Sbjct: 687 EEMQVLREG-------HESEIKDFIEEHSKLTKQLDDIKNQFGIISSK------------ 727
Query: 198 ELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQL 257
N+ L +L +K L N A E K + ND+ LL KL++
Sbjct: 728 --------NRDLLSELEKSKSLN--NSLAALESKNKKLENDLN--------LLTEKLNKK 769
Query: 258 NSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITEL-NMLQRENTFLLDTNSK 316
N+ + F++ E L +K L+ N ++I++L N L E+T L + S+
Sbjct: 770 NADTESFKNTIRE-AELSKKA-------LNDNLGNKENIISDLKNKLSEESTRLQELQSQ 821
Query: 317 LQIDFNQMSMLNDEM---AIERNQLLDLNKDYETSILNLKRLNHELEQ------------ 361
L D NQ+ LN+ + A E + + +NK+ + K+ L++
Sbjct: 822 LNQDKNQIETLNERISAAADELSSMESINKNQANELKLAKQKCSNLQEKINFGNKLAKEH 881
Query: 362 -QKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNE-LKRLNE 419
+K+ S E+ + + ++ +N+ + + NE K +++
Sbjct: 882 TEKISSLEK-DLEAATKTASTLSKELKTVKSENDSLKSVSNDDQNKEKSVNNEKFKEVSQ 940
Query: 420 ELSKTDDKIQKR 431
L++ ++K+ R
Sbjct: 941 ALAEANEKLNAR 952
>Hs4505301 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 61.6 bits (148), Expect = 4e-09
Identities = 82/362 (22%), Positives = 153/362 (41%), Gaps = 62/362 (17%)
Query: 30 KYTTLQNEYEISKLSSER---ETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL-- 84
KY Q E E S+ S E + ++N Y++S+++LE + K L +E L E++
Sbjct: 1462 KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAE 1521
Query: 85 ---------KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTN 135
K K + +E +I L SL++E E +I+ + +L+ ++EV
Sbjct: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHE----EGKILRIQLELNQVKSEVDR 1577
Query: 136 AIESMKLEIEG-SGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNN 194
I EI+ N ET + EIR L+ K+ + +L ++ +H N
Sbjct: 1578 KIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637
Query: 195 STEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL 254
E +L+ N L++ L L+ + +++++ LLQ+++
Sbjct: 1638 LAAE---------SLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 255 DQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTN 314
++L + ++ E I+ QE + D + +L +NT L++T
Sbjct: 1689 EELWATLEQTE--RSRKIAEQELL----------------DASERVQLLHTQNTSLINTK 1730
Query: 315 SKLQIDFNQMSMLNDEMAIE-RN--------------QLLDLNKDYETSILNLKRLNHEL 359
KL+ D +Q+ +E+ E RN +L K+ +TS +L+R+ L
Sbjct: 1731 KKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNL 1789
Query: 360 EQ 361
EQ
Sbjct: 1790 EQ 1791
Score = 58.5 bits (140), Expect = 3e-08
Identities = 105/556 (18%), Positives = 207/556 (36%), Gaps = 88/556 (15%)
Query: 44 SSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRT 103
S E + L+ K ++ + + L E + +L +DAL + +
Sbjct: 1254 SLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQ 1313
Query: 104 QVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH----------- 152
Q+ LK+++ + + LAH L S +++ E + E EG +
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 1373
Query: 153 ---QHETQINKHVEEI----RYLQQELKEKENLI----SELRSVQTSASHRNNSTEELQ- 200
++ET + EE+ + L Q L+E E + ++ S++ + N E+L
Sbjct: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLML 1433
Query: 201 DLAVLNKTL----KEQLNYAKELEDMNLK----QATELKKLRQNNDVQSLLKKENELLQS 252
D+ N K+Q N+ K L + K QA +++ + + L K + +
Sbjct: 1434 DVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 253 KLDQLNSLQKKFESLEMENISLQEKITQWG--IVRLDGKFKNPNDVITELNMLQRENTFL 310
LDQL +L++ ++L+ E L E+I + G I L+ K E+ E
Sbjct: 1494 SLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEAS 1553
Query: 311 LDTNS----KLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLS 366
L+ ++Q++ NQ+ D E+++ +D K T ++ + + E
Sbjct: 1554 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE------ 1607
Query: 367 FEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDD 426
+ D + +EG N+ E N RL E
Sbjct: 1608 --------------------IRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE------ 1641
Query: 427 KIQKRRKITNDLGI--SYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKK 484
R N GI + + AN+L+ +I +L + E+
Sbjct: 1642 ---SLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQT 1698
Query: 485 VRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEI 544
R ++ + LL E++ LL +N+ L+ + ++++D+ L+ E+
Sbjct: 1699 ERSRKIAEQELLD----ASERVQLLHTQNTSLI----------NTKKKLENDVSQLQSEV 1744
Query: 545 FSANKKTTRLKEVFNK 560
+++ +E K
Sbjct: 1745 EEVIQESRNAEEKAKK 1760
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 61.2 bits (147), Expect = 5e-09
Identities = 71/341 (20%), Positives = 145/341 (41%), Gaps = 59/341 (17%)
Query: 48 ETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL-----------KSKDALPKEDEK 96
E + ++N Y++S+++LE ++ K L +E L E++ K K + +E +
Sbjct: 1486 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCE 1545
Query: 97 IITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEG-SGNILHQHE 155
+ L SL++E E +I+ + +L+ ++EV I EI+ N + E
Sbjct: 1546 LQAALEEAEASLEHE----EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVE 1601
Query: 156 TQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNY 215
+ + EIR ++ K+ + +L ++ +H N E L+ N
Sbjct: 1602 SMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE---------ALRNYRNT 1652
Query: 216 AKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQ 275
L+D + L+ + +++++ LLQ+++++L + ++ E I+ Q
Sbjct: 1653 QGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE--RSRKIAEQ 1710
Query: 276 EKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQM-SMLNDEMAIE 334
E + D + +L +NT L++T KL+ D +QM + D +
Sbjct: 1711 ELL----------------DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEA 1754
Query: 335 RN--------------QLLDLNKDYETSILNLKRLNHELEQ 361
RN +L K+ +TS +L+R+ +EQ
Sbjct: 1755 RNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNMEQ 1794
Score = 57.0 bits (136), Expect = 9e-08
Identities = 114/586 (19%), Positives = 231/586 (38%), Gaps = 113/586 (19%)
Query: 68 KDTKILYEENIKLKEELKSKDALPKE-DEKIITTLRT----------------------- 103
K+ + EE K+K+EL +A KE +EK++T L+
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912
Query: 104 QVVSLKNEVNLKEQRIVELAH-------KLSSKQNEVTNAIESMKLEIEGSGNILHQHET 156
Q++ K ++ K + + E A +L++K+ ++ + +K +I+ L + E
Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 972
Query: 157 QINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAV----LNKTLKEQ 212
+ + +++ L +E+ + I++L + + + T L DL +N K +
Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT--LDDLQAEEDKVNTLTKAK 1030
Query: 213 LNYAKELEDM--NLKQATELK--------------KLRQNN--DVQSLLKKENELLQSKL 254
+ ++++D+ +L+Q +L+ KL Q + D+++ ++ +E L+ K
Sbjct: 1031 IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKE 1090
Query: 255 DQLNSLQKKFESLEMENISLQEKI--TQWGIVRLDGKF-----------KNPNDVITELN 301
++++LQ K E + I LQ+KI Q I L+ + K +D+ EL
Sbjct: 1091 FEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 302 MLQRE-------NTFLLDTNSKLQIDFNQMSMLNDEMAIE--------RNQLLDLNKDYE 346
+ + ++ N K + +F +M +E ++ R + D +
Sbjct: 1151 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG 1210
Query: 347 TSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQ 406
I NL+R+ +LE++K E A +E
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS-------------KAKGNLEKMCRT 1257
Query: 407 TEDLTNELKRLNEELSK-TDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKN 465
ED +ELK EE + +D +R ++ + G +S+ A
Sbjct: 1258 LEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG-EFSRQLDEKEALVSQLSRGKQAFTQ 1316
Query: 466 HANILEQKILDLTSLKEKKVRILQ--LRDNPLLKEHY-----IRKEKLALLEKENSDLL- 517
L++++ + K LQ D LL+E Y + E L K N+++
Sbjct: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376
Query: 518 --SGIETDAIPRS-----VYDRIKHDMKLLEKEIFSANKKTTRLKE 556
+ ETDAI R+ ++ ++ E+ + + N K L++
Sbjct: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1422
Score = 53.9 bits (128), Expect = 7e-07
Identities = 109/556 (19%), Positives = 210/556 (37%), Gaps = 81/556 (14%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL 67
KEK ++ D L V T+ L+ + E + L++K ++ + +
Sbjct: 1225 KEKSEMKMEIDDLASNVETVSKAKGNLEKMCR----TLEDQLSELKSKEEEQQRLINDLT 1280
Query: 68 KDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLS 127
L E+ + +L K+AL + + Q+ LK ++ + + LAH L
Sbjct: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 128 SKQNEVTNAIESMKLEIEGSGNILH--------------QHETQINKHVEEIRYLQQELK 173
S +++ E + E E + ++ET + EE+ +++L
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 174 EK--------ENLISELRSVQTSASHRNNSTEELQ-DLAVLNKTL----KEQLNYAKELE 220
++ E + ++ S++ + N E+L D+ N K+Q N+ K L
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
Query: 221 DMNLK-QATELKKLRQNNDVQSL---LKKENELLQSKLDQLNSLQKKFESLEMENISLQE 276
+ K + T + + +SL L K + LDQL +L+++ ++L+ E L E
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
Query: 277 KITQWG--IVRLDGKFKNPNDVITELNMLQRENTFLLDTNS----KLQIDFNQMSMLNDE 330
+I + G I L+ K EL E L+ ++Q++ NQ+ D
Sbjct: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Query: 331 MAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTP 390
E+++ +D LKR NH + + S +
Sbjct: 1581 KIAEKDEEID----------QLKR-NHIRIVESMQS---------------TLDAEIRSR 1614
Query: 391 GDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXX 450
D + +EG N+ E N R+ E + + + I D I
Sbjct: 1615 NDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR---NYRNTQGILKDTQIHLDD----AL 1667
Query: 451 XXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLE 510
+ + AN+L+ +I +L + E+ R ++ + LL E++ LL
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLD----ASERVQLLH 1723
Query: 511 KENSDLLS---GIETD 523
+N+ L++ +ETD
Sbjct: 1724 TQNTSLINTKKKLETD 1739
Score = 53.5 bits (127), Expect = 1e-06
Identities = 79/361 (21%), Positives = 154/361 (41%), Gaps = 52/361 (14%)
Query: 16 DADQLRRR-VLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILY 74
+ DQL+R + ++ +TL E + S + L+ K + +NE+E L +
Sbjct: 1588 EIDQLKRNHIRIVESMQSTLDAE-----IRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642
Query: 75 EENIK--------LKE-ELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHK 125
E ++ LK+ ++ DAL +++ L+ Q+ ++ NL + I EL
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQED-----LKEQLAMVERRANLLQAEIEELRAT 1697
Query: 126 LSSKQNEVTNAI-ESMKLEIEGSGNILHQHETQINKHVEEIRY-LQQELKEKENLISELR 183
L +Q E + I E L+ +LH T + +++ + Q E E+++ E R
Sbjct: 1698 L--EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEAR 1755
Query: 184 SVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDM--NLKQATELKKLRQNNDVQS 241
+ + A + + D A++ + LK++ + + LE M N++Q + +LR + Q
Sbjct: 1756 NAEEKAK------KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQL 1809
Query: 242 LLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELN 301
LK + +Q ++ L+ + ES + N + G+ + + + K +T
Sbjct: 1810 ALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVK-----GLRKHERRVKE----LTYQT 1860
Query: 302 MLQRENTFLL-DTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELE 360
R+N L D KLQ +E + N T++ ++L HELE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN----------TNLAKFRKLQHELE 1910
Query: 361 Q 361
+
Sbjct: 1911 E 1911
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 61.2 bits (147), Expect = 5e-09
Identities = 80/356 (22%), Positives = 156/356 (43%), Gaps = 41/356 (11%)
Query: 35 QNEYEISKLSSERETYSLQNKYDKSMN--------ELENALKDTKILYEENIKLKEELKS 86
QNE KL++ RE ++ + ++ N +LE AL + K+L ++ +K
Sbjct: 850 QNEKLEDKLAAVREQMIVERQAARTANLSLWKVEKQLEEALSEKKLLARRMELTEDRIKK 909
Query: 87 KDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTN--------AIE 138
E ++++ T + E +E RI EL +L++ + +V E
Sbjct: 910 VQNASDEAQRMLKT-------SQEETRQRESRIEELKQELAAAKRDVLKEHRQWEKAEQE 962
Query: 139 SMKLE---IEGSGNI--LHQHETQINKHVEEIR-YLQQELKEKENLISELRSVQTSASHR 192
MK + IE N+ L Q ET++ + + +I+ E++N I EL+ + +
Sbjct: 963 RMKCKSEIIEHLANVHRLEQQETELRQKLRQIQSRFDGVTLEQKNTIRELQEEREKSRKA 1022
Query: 193 NNSTEELQ-DLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQ--NNDVQSLLKKENEL 249
N+S LQ +L L ++L YA + D L + + K Q N +S L +E
Sbjct: 1023 NDSCLVLQKELKQLTDNF-QRLKYACSITDSQLTEVETMLKSEQERNKSQKSQLDTLHEK 1081
Query: 250 LQSKLDQLNSLQKKFESLEMENISLQEK----ITQWGIVRLDGKFKNPNDVITELNMLQR 305
L+ + DQL L+K+ ++E E +++ ++ +RL+ K + ++ + + L
Sbjct: 1082 LRERNDQLTDLRKQLTTVESEKRLAEQRAQVLASEIDELRLNLK-EQQKKLVAQQDQLVE 1140
Query: 306 ENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQ 361
+ L T + ++ Q + + A +++ L E + L L H+ E+
Sbjct: 1141 QTNALFATQERAELLDGQNANYEAQTADSNREMVSLK---EENARILSELFHKKEE 1193
Score = 57.0 bits (136), Expect = 9e-08
Identities = 66/323 (20%), Positives = 126/323 (38%), Gaps = 47/323 (14%)
Query: 7 IKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENA 66
+++ + + ++L+ ++ L K T +NE + K R SL+ +KS
Sbjct: 450 MEKSAISATTDEKLQEKLKELLQKLKTRENEISMLKQDLLRAQQSLRKTDNKSQ-----V 504
Query: 67 LKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNL-------KEQRI 119
+ D K+ E+K + KE +TT +TQ+ +L++ + KE I
Sbjct: 505 VADAKM----------EIKKLQQIIKEKTMELTTCKTQIKTLQSSAKIDEEMWSKKEATI 554
Query: 120 VELAHKLSSKQNEVTNAIE--------SMKLEIEGSGNILHQHETQINKHVEEIRYLQQE 171
+L K E A E K E+ + L E + N EE ++L +
Sbjct: 555 TDLLRLNRQKYEEAKIASEQRYEKQLADKKQELASTLQKLDARELEFNAKFEECKHLSMK 614
Query: 172 LKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELK 231
L+ ++++ +++ Q S N+ + Q + + L + ++ +D N + E+K
Sbjct: 615 LQNYKDMLQQIKE-QNLKSETNHEEQRRQMAELYEQKLTDLRKKVRDSQDTNRRMTMEIK 673
Query: 232 KLRQNND--------VQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGI 283
++R D Q ++ L +LN L E + L+ K
Sbjct: 674 EIRTELDESISSSKSTQEAKNATERNIEEILRRLNEEIASNNELHAEKVKLETK------ 727
Query: 284 VRLDGKFKNPNDVITELNMLQRE 306
L K +V E + L+RE
Sbjct: 728 --LQLKENETQEVRAECHRLERE 748
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 61.2 bits (147), Expect = 5e-09
Identities = 78/368 (21%), Positives = 158/368 (42%), Gaps = 38/368 (10%)
Query: 14 SLDADQLRRRVLTLQYKYTTLQNEYE-----ISKLSSERETYSLQNKYDKSMNELENALK 68
SL + RR+ L+ + L + + + L S N+ DK + +L ++
Sbjct: 437 SLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNR-DKEIKKLNEEIE 495
Query: 69 DTKILYEENIKLKEELKSKDALPKEDEKIITTLR---TQVVSLKNEVNLKEQRIVELAHK 125
K ++ +L+ +L+ AL +E E LR Q ++ E +++VE + +
Sbjct: 496 RLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASER 555
Query: 126 LSSKQNEVTNAIESMKLEIEGSGNI---LHQHETQINKHVEEIRYLQQELKEKENLISEL 182
L S+ E+ +A + KL ++ + + + Q K ++R ++E++ + +
Sbjct: 556 LKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAM 615
Query: 183 RSVQTSASHRNNSTEELQDLAVLNKTLKEQL-----NYAK----ELEDMNLKQA-----T 228
R A E D AV + + +L N+ K ELE + +KQ
Sbjct: 616 RQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQGGRGAGA 675
Query: 229 ELKKLRQNNDVQSLLKK-----ENELLQ---SKLDQLNSLQKKFESLEMENISLQEKITQ 280
L+ ++ + ++S L+K E EL++ S + ++ +++K+ E ++LQ++I
Sbjct: 676 TLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEILM 735
Query: 281 WGIVRLDGKFKNPND----VITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERN 336
K + N+ V T + +RE L D N KL + ++ D++ +
Sbjct: 736 LKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNR 795
Query: 337 QLLDLNKD 344
QL D +D
Sbjct: 796 QLEDELQD 803
>YLR086w [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1418
Score = 60.8 bits (146), Expect = 6e-09
Identities = 69/320 (21%), Positives = 142/320 (43%), Gaps = 35/320 (10%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL 67
KE LE L+ ++ + + +++ LQ+ SKL+S E S NK L
Sbjct: 375 KETALEFLEKEKQLTLLRSKLFQFKLLQSN---SKLASTLEKISSSNK----------DL 421
Query: 68 KDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLS 127
+D K+ ++E++K +E+K++ K+ ++ +V + E+ + E L
Sbjct: 422 EDEKMKFQESLKKVDEIKAQRKEIKDRISSCSSKEKTLVLERRELEGTRVSLEERTKNLV 481
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELR-SVQ 186
SK + ++S K I + N+L + Q +H EI+ L Q L+++ +++ +++ S++
Sbjct: 482 SKMEKAEKTLKSTKHSISEAENMLEELRGQQTEHETEIKDLTQLLEKERSILDDIKLSLK 541
Query: 187 TSASH------RNNSTEELQDLAVLNKTLKEQL----------NYAKELEDMNLKQATEL 230
+ R+ E DL + K + QL AK +++ + L
Sbjct: 542 DKTKNISAEIIRHEKELEPWDLQLQEKESQIQLAESELSLLEETQAKLKKNVETLEEKIL 601
Query: 231 KKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLD--- 287
K ++Q L+ + L S D+ + +K F S ++ +Q+ + ++
Sbjct: 602 AKKTHKQELQDLILDLKKKLNSLKDERSQGEKNFTSAHLKLKEMQKVLNAHRQRAMEARS 661
Query: 288 --GKFKNPNDVITELNMLQR 305
K +N + V+T L+ LQ+
Sbjct: 662 SLSKAQNKSKVLTALSRLQK 681
>Hs17978507 [Z] KOG0161 Myosin class II heavy chain
Length = 1581
Score = 60.8 bits (146), Expect = 6e-09
Identities = 139/704 (19%), Positives = 272/704 (37%), Gaps = 110/704 (15%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEIS----------KLSSERETYSLQNKYD 57
KE+ L++D+L R+ L + T +N E + +L +E+E LQ +YD
Sbjct: 817 KERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYD 876
Query: 58 ---KSMNELENALKDTKIL---------------------YEENIKLKEELKSKDALPKE 93
K M +E + + +++ YE ++ + K + E
Sbjct: 877 ALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 936
Query: 94 DE-KIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILH 152
D+ ++ + Q+ ++ + +L K +T ++ KL +EG H
Sbjct: 937 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 996
Query: 153 QHETQINKHVEEIRYLQQEL-----------KEKENLISELRSVQTSASHRN-------- 193
+ E + + E+ +E +EK+ L++E S++ ++
Sbjct: 997 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ 1056
Query: 194 ---NSTEELQDLAVLNKTLKEQLNYA---KELEDMNLKQATELKKL-RQNNDVQSL---- 242
+ ELQD++ ++ K++ + A K+L D+ K + ++L Q +Q L
Sbjct: 1057 KVVSLEAELQDIS--SQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAK 1114
Query: 243 LKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNM 302
L+ E E+ + + ++ + E +E S Q+K+ Q V+L+ ++++ V+ E
Sbjct: 1115 LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME-VQLEEEYEDKQKVLREKRE 1173
Query: 303 LQRENTFLLDTNSKLQIDFNQMSMLNDE------MAIERNQLLDLNKDYETSILNLKRLN 356
L+ + L D ++ DF L + + + +LD K+ S + +L
Sbjct: 1174 LEGKLATLSDQVNRR--DFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLK 1231
Query: 357 HELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKR 416
++LE+ + F D A +E ++ + NE++
Sbjct: 1232 NQLEESE---FTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQN 1288
Query: 417 LNEELSKTDDKIQKRRKIT-----------NDLGISYSQXXXXXXXXXXXXXXXXSATKN 465
EE + +++ K+ K NDL + A ++
Sbjct: 1289 RLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE----ANKEKQELQEKLQALQS 1344
Query: 466 HANILEQKILD--LTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETD 523
LEQ ++D L S +E K+R L+ R + R E LA KEN + L+
Sbjct: 1345 QVEFLEQSMVDKSLVSRQEAKIRELETR-LEFERTQVKRLESLASRLKENMEKLTEERDQ 1403
Query: 524 AIPRSVYDRIKHDMKLLEKEIFSANKKTTRL----KEVFNKK-----SLEFIEAVNSLL- 573
I + +R K K L++++ ++ L E KK LE +EA N L
Sbjct: 1404 RI--AAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQ 1461
Query: 574 -GFKLEFLAHGKVKLVSCYQPNKYIIADLQSNTLKSDLDKVIPE 616
KL F G ++ + DL ++ SD+D + +
Sbjct: 1462 ADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELED 1505
Score = 55.1 bits (131), Expect = 3e-07
Identities = 93/410 (22%), Positives = 179/410 (42%), Gaps = 76/410 (18%)
Query: 2 SLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSE--RETYSLQNKYDKS 59
SL Q++EK +D ++V++L E E+ +SS+ ++ SL K K
Sbjct: 1039 SLKQQLEEK---DMDIAGFTQKVVSL---------EAELQDISSQESKDEASLA-KVKKQ 1085
Query: 60 MNELENALKDTKILYEEN---IKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKE 116
+ +LE +KD + +E I++ E+ K + L E E++ T ++ S EV
Sbjct: 1086 LRDLEAKVKDQEEELDEQAGTIQMLEQAKLR--LEMEMERMRQTHSKEMESRDEEVEEAR 1143
Query: 117 Q----RIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKH-VEEIRYLQQE 171
Q ++ ++ +L + + + K E+EG L Q+N+ E + L+++
Sbjct: 1144 QSCQKKLKQMEVQLEEEYEDKQKVLRE-KRELEGK---LATLSDQVNRRDFESEKRLRKD 1199
Query: 172 LKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKE-----------QLNYAKELE 220
LK + L+++ Q H NS +++A L L+E + E+E
Sbjct: 1200 LKRTKALLAD---AQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIE 1256
Query: 221 DMNL--------KQATE--LKKL-RQNNDVQSLLKKE----NELLQSK----------LD 255
D++L K A E L +L R+ N++Q+ L+++ NEL++ L
Sbjct: 1257 DLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA 1316
Query: 256 QLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNS 315
Q+N LQ + E E LQEK+ L + + + + +++ R+ + + +
Sbjct: 1317 QINDLQAQLEEANKEKQELQEKLQ-----ALQSQVEFLEQSMVDKSLVSRQEAKIRELET 1371
Query: 316 KLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLL 365
+L+ + Q+ L + + + L ++ + I N E EQ K L
Sbjct: 1372 RLEFERTQVKRLESLASRLKENMEKLTEERDQRI---AAENREKEQNKRL 1418
>Hs14764231 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1233
Score = 60.5 bits (145), Expect = 8e-09
Identities = 71/331 (21%), Positives = 148/331 (44%), Gaps = 36/331 (10%)
Query: 52 LQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNE 111
L +YDK E+ A +DT+ Y + E K KE+ L+ +VV + +
Sbjct: 164 LAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQ-EKEEADRYQRLKDEVVRAQVQ 222
Query: 112 VNL-----KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIR 166
+ L E I +L +L+SK E IE K ++ + L + + ++ K + E +
Sbjct: 223 LQLFKLYHNEVEIEKLNKELASKNKE----IEKDKKRMDKVEDELKEKKKELGKMMREQQ 278
Query: 167 YLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKE-QLNYAKELEDMNLK 225
+++E+KEK++ +++ R A + N++ +++ L K+L+ Q +Y K DM+
Sbjct: 279 QIEKEIKEKDSELNQKRPQYIKA--KENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDEL 336
Query: 226 QATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL-------------EMENI 272
+ L + + + +++E++ L + KK+ L E+E
Sbjct: 337 EKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKF 396
Query: 273 SLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMA 332
+ +K Q RLD + + + ++ RE ++ N K +I+ + + + +
Sbjct: 397 NRDQKADQ---DRLDLEERKKVETEAKIKQKLRE----IEENQK-RIEKLEEYITTSKQS 448
Query: 333 IERNQLL--DLNKDYETSILNLKRLNHELEQ 361
+E + L +L ++ E + + +N EL Q
Sbjct: 449 LEEQKKLEGELTEEVEMAKRRIDEINKELNQ 479
Score = 52.0 bits (123), Expect = 3e-06
Identities = 71/310 (22%), Positives = 133/310 (42%), Gaps = 34/310 (10%)
Query: 2 SLTPQIKEKPLESLDADQLRR---RVLTLQYK---YTTLQNEYEISKLSSERETYSLQNK 55
++ + KE E +AD+ +R V+ Q + + NE EI KL+ E + + + +
Sbjct: 191 NIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIE 250
Query: 56 YDKS-MNELENALKDTKI----LYEENIKLKEELKSKDA-----------LPKEDEKIIT 99
DK M+++E+ LK+ K + E ++++E+K KD+ + I
Sbjct: 251 KDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIK 310
Query: 100 TLRTQVVSLKNEVNLKEQR---IVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHET 156
L SL+N ++R + EL ++ S + E M+ E + G L E
Sbjct: 311 KLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEEN 370
Query: 157 QINKHVEEIRYLQQELKEKENLISELRSV---QTSASHRNNSTE--ELQDLAVLNKTLKE 211
Q+ K+ R ++ K L EL Q + R + E +++ A + + L+E
Sbjct: 371 QVKKY---HRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 212 QLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLN-SLQKKFESLEME 270
K +E + T + L + ++ L +E E+ + ++D++N L + E L
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 271 NISLQEKITQ 280
I QE Q
Sbjct: 488 RIDRQESSRQ 497
>Hs4505993 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 1756
Score = 60.1 bits (144), Expect = 1e-08
Identities = 83/377 (22%), Positives = 156/377 (41%), Gaps = 48/377 (12%)
Query: 27 LQYKYTTLQNEYEISKLSSER-ETYSLQNKYDKSMNELEN---ALKDTK----------- 71
++YK T + E E+ +L E + L + D + +L+ ALKDTK
Sbjct: 1236 IKYK-TDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQE 1294
Query: 72 -ILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQ 130
+ ++E+ + KEE+ S A E++K L + S + ++ KE+ + + ++ Q
Sbjct: 1295 ILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERV--VQ 1352
Query: 131 NEVTNAIESMKLEIEGS--GNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTS 188
EV E L E S + QI+K E+R LQ+ E E + EL + +
Sbjct: 1353 QEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQA 1412
Query: 189 ASHRNNSTEELQD-LAVLNKTLKEQLNYAKELEDMNLKQATELKK--------LRQNNDV 239
+ LQ LA L + E + + L+Q + + L +
Sbjct: 1413 RREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHR 1472
Query: 240 QSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVR----LDGKFKNPND 295
+ LL+ E E L+ KL L + K + + E++ +++ T+ I R L+ + ++ +
Sbjct: 1473 RQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRE 1532
Query: 296 VITELNMLQ--------------RENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDL 341
+ E++ L+ +E FL + N KLQ++ + + + E N
Sbjct: 1533 LDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRLQSEINMAATE 1592
Query: 342 NKDYETSILNLKRLNHE 358
+D + NH+
Sbjct: 1593 TRDLRNMTVADSGTNHD 1609
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 60.1 bits (144), Expect = 1e-08
Identities = 129/644 (20%), Positives = 251/644 (38%), Gaps = 120/644 (18%)
Query: 31 YTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSK--- 87
+T + +S S RET S+Q++ ++ E++ L + ++ KEEL+ K
Sbjct: 413 FTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKS 472
Query: 88 -----DALPKEDEKIITTLRTQVVS----LKNEVNLKEQRIVELAHKL---SSKQNEVTN 135
+ KE E+ I TLR V S L+ E L + + E K + K+ + N
Sbjct: 473 VNTRLEKTAKELEEEI-TLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLEN 531
Query: 136 AIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLI-------SELRSVQTS 188
+ S+K ++E L + E++ LQ++L E L+ + LR Q
Sbjct: 532 DVNSLKDQLED----LKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAE 587
Query: 189 ASHR----NNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQN------ND 238
+S + ++ +LQD L +T K +L E E +NL+ A E ++ + ND
Sbjct: 588 SSKQIQQLESNNRDLQDKNCLLETAKLKL----EKEFINLQSALESERRDRTHGSEIIND 643
Query: 239 VQSLL------KKENELLQSKLD-QLNSLQKKFESLEME------NISLQEKITQWGIVR 285
+Q + K ++L +K++ + LQ++F LE E +++ Q K+ Q + +
Sbjct: 644 LQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQ 703
Query: 286 LDGKFK--------------------------NPNDVITELNMLQRENTFLLDTN---SK 316
+ + K ++ E + Q+ LL+ S
Sbjct: 704 EEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSL 763
Query: 317 LQIDFNQMSMLNDEMAIE--------RNQLLDLNKDYETSILNLKRLNHELEQQKLLSFE 368
L D Q +E+ + RN L + ++ + L L + +Q L
Sbjct: 764 LDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMS 823
Query: 369 ECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTED--------------LTNEL 414
E + +G + +D EL
Sbjct: 824 EKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVREL 883
Query: 415 KRLNEELSKTDDKI-QKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQK 473
K EE +K ++ QK++++ ++ +Q A + ++++ ++K
Sbjct: 884 KEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEK 943
Query: 474 ILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGI-----ETDAIPRS 528
I +KE +++ + R L E + +A LE+ N L S + E + +
Sbjct: 944 I-----MKELEIKEMMARHKQELTE---KDATIASLEETNRTLTSDVANLANEKEELNNK 995
Query: 529 VYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSL 572
+ D + +L ++EI +A K K++ +++L+ +AVN L
Sbjct: 996 LKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLK-TQAVNKL 1038
Score = 57.8 bits (138), Expect = 5e-08
Identities = 85/369 (23%), Positives = 162/369 (43%), Gaps = 68/369 (18%)
Query: 23 RVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKI-LYEENIKLK 81
R LTL+ + T + + L + + + +K + + N L + K+ L ++N +L+
Sbjct: 790 RNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELR 849
Query: 82 EELKSKDALPKE-------DEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVT 134
+E + D KE ++ T +TQV LK E K +L +L K+ E+
Sbjct: 850 KERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEK----TKLGKELQQKKQELQ 905
Query: 135 NAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNN 194
+ +S+ ++E + + Q+ + + E +Y E KE ++ EL + A H+
Sbjct: 906 DERDSLAAQLEIT--LTKADSEQLARSIAEEQYSDLE---KEKIMKELEIKEMMARHKQE 960
Query: 195 STEELQDLAVL---NKTLKEQL-NYAKELEDMNLK------QATELK------------- 231
TE+ +A L N+TL + N A E E++N K Q + LK
Sbjct: 961 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF 1020
Query: 232 ----------KLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQW 281
K + N + ++ ++ + + + +K+ L ME S +EK+TQ
Sbjct: 1021 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ 1080
Query: 282 GIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIE--RNQLL 339
I K++ ELN +Q + + S+++I+ QM++ + + IE R+QL
Sbjct: 1081 MI-----KYQK------ELNEMQAQ----IAEESQIRIEL-QMTLDSKDSDIEQLRSQLQ 1124
Query: 340 DLNKDYETS 348
L+ ++S
Sbjct: 1125 ALHIGLDSS 1133
Score = 52.4 bits (124), Expect = 2e-06
Identities = 90/414 (21%), Positives = 166/414 (39%), Gaps = 61/414 (14%)
Query: 27 LQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELK- 85
LQ ++T L+ E ++ TY L+ +S+ + E K TK + K+ E ++
Sbjct: 672 LQERFTDLEKEKSNMEIDM---TYQLK-VIQQSLEQEEAEHKATKARLADKNKIYESIEE 727
Query: 86 SKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIE 145
+K KE EK + RT ++N + E+R L L Q ++ ++ + E
Sbjct: 728 AKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNE 787
Query: 146 GSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVL 205
N+ + E + K Q +LK + T+++ L +
Sbjct: 788 DVRNLTLKIEQETQKRC----LTQNDLKMQ--------------------TQQVNTLKMS 823
Query: 206 NKTLKEQLNYAKELEDMNL-KQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKF 264
K LK++ N+ E++ MNL KQ EL+K RQ+ D Q ++ DQL + Q
Sbjct: 824 EKQLKQENNHLMEMK-MNLEKQNAELRKERQDADGQ---------MKELQDQLEAEQYFS 873
Query: 265 ESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQM 324
+ + L+E+ + K K ++ + LQ E L ++L+I +
Sbjct: 874 TLYKTQVRELKEECEE--------KTKLGKELQQKKQELQDERDSLA---AQLEITLTKA 922
Query: 325 SMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXX 384
+I Q DL K+ ++ ELE +++++ +
Sbjct: 923 DSEQLARSIAEEQYSDLEKE---------KIMKELEIKEMMARHKQELTEKDATIASLEE 973
Query: 385 XXXXTPGDQVNASNIIEGYKNQTEDLTNELKRL-NEELSKTDDKIQKRRKITND 437
D N +N E N+ +D+ +L RL +EE+S K Q +++ +
Sbjct: 974 TNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTE 1027
>YHR023w [Z] KOG0161 Myosin class II heavy chain
Length = 1928
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/353 (22%), Positives = 156/353 (43%), Gaps = 51/353 (14%)
Query: 40 ISKLSSERETYSLQNKYDKSMNELENALKDT----KILYEENIKLKEELK-SKDALPKED 94
I L + + K+++ +N+L+N L++ K L E+N K EL+ ++D L +E
Sbjct: 850 IKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEK 909
Query: 95 EKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQH 154
E + + SL N V + + + L S+++E++ KLE+ + HQ
Sbjct: 910 ENL-----RKNESLLNRVKTSSETLQKQFDDLVSEKDEISRE----KLEVAQNLEEAHQ- 959
Query: 155 ETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLN 214
+I+ LQ+ ++E+E + +L S +NN E ++ ++ LN + ++ +
Sbjct: 960 ---------KIQGLQETIREREATLEKLHS-------KNN--ELIKQISDLNCDISKEQS 1001
Query: 215 YAKELEDMNLKQATELKKLRQ-NNDVQSLLKKENELLQSKLDQL-----------NSLQK 262
+++ LK E+K+L+ N + +K N+ L S + L N
Sbjct: 1002 SQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTLEKNCNIAMS 1061
Query: 263 KFESLEMENISLQEKITQWGIVR--LDGKFKNPNDVITELNMLQRENTFLLDTNSKLQID 320
+ +SL EN L+ K + + L+ + KN + ++ + L T SK + D
Sbjct: 1062 RLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDD 1121
Query: 321 -FNQMSMLNDEMAIERNQLLDLNKDYE---TSILNLKRLNHELEQQKLLSFEE 369
++ + E+ R QL + +Y+ N +R E EQ+K S E
Sbjct: 1122 AVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQEQKKRNSLVE 1174
Score = 55.5 bits (132), Expect = 3e-07
Identities = 110/550 (20%), Positives = 211/550 (38%), Gaps = 80/550 (14%)
Query: 71 KILYEENIKLKEELKSKDALPKED-EKIITTLR--TQVVSLKNE---------VNLKEQR 118
+ILY EN A K++ E ++T+L+ T+V + N +L++Q+
Sbjct: 731 RILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQK 790
Query: 119 IVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKE-- 176
V KL++ ++T I + E + ++ +T++ + R + +KE
Sbjct: 791 DV----KLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNT--FRLYNRLVKEDPWF 844
Query: 177 NLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQN 236
NL ++ + TS++ + + + + L L+E + K LE+ N K EL+ +
Sbjct: 845 NLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDL 904
Query: 237 -NDVQSLLKKENELLQSKLDQLNSLQKKFESL--EMENISLQEKITQWGIVRLDGKFKNP 293
N + L+K LL +LQK+F+ L E + IS ++ + K +
Sbjct: 905 LNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGL 964
Query: 294 NDVITE----LNMLQRENTFLLDTNSKLQIDFNQ----MSMLNDEMAIERNQLLDLNKDY 345
+ I E L L +N L+ S L D ++ S++ + N++ L
Sbjct: 965 QETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVI 1024
Query: 346 ETSILNLKRLNHELEQQ------KLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNI 399
+ +K N +L KL++ E+ T + + N
Sbjct: 1025 NSKEEEIKSFNDKLSSSEEDLDIKLVTLEK------NCNIAMSRLQSLVTENSDLRSKN- 1077
Query: 400 IEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXX 459
E +K + L N+LK EL K +KI +K
Sbjct: 1078 -ENFKKEKAALNNQLKNKESELLKMKEKIDNHKK-----------------ELATFSKQR 1119
Query: 460 XSATKNHANILEQKILDLTSLKEKKVRILQLRDN-PLLKEHY--IRKEKLALLEKENSDL 516
A H I + LKE ++++ + + N +KE Y ++E +K+ + L
Sbjct: 1120 DDAVSEHGKITAE-------LKETRIQLTEYKSNYQKIKEEYSNFQRETKEQEQKKRNSL 1172
Query: 517 LSGIETDAIPRSVYDRIKHDMKL---LEKEI----FSANKKTTRLKEVFNKKSLEFIEAV 569
+ + I + + R+ ++ L L K I N +TR ++ L+ + +
Sbjct: 1173 VESLNDSKI-KELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDII 1231
Query: 570 NSLLGFKLEF 579
+L F
Sbjct: 1232 KKYYDLQLAF 1241
Score = 55.1 bits (131), Expect = 3e-07
Identities = 132/620 (21%), Positives = 233/620 (37%), Gaps = 117/620 (18%)
Query: 34 LQNEYEISKLSSERETYSLQNKYDKSMNE---LENALKDTKIL---YEENI-KLKEELKS 86
L+ + +I E T+S Q D +++E + LK+T+I Y+ N K+KEE +
Sbjct: 1099 LKMKEKIDNHKKELATFSKQR--DDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSN 1156
Query: 87 KDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQ--------NEVTNAIE 138
KE E+ R +V N+ +KE L+ ++S Q N V I
Sbjct: 1157 FQRETKEQEQ---KKRNSLVESLNDSKIKELE-ARLSQEISLNQYLNKRISGNSVETNIS 1212
Query: 139 SMKLEIEGSGNILHQHETQINKH-------VEEIRYLQQELKEKENLISELRSVQTSASH 191
S + S + L + + I K+ E R L+ E++EK+NLIS LR +T +
Sbjct: 1213 STRRSTSYSDDPLDKEDI-IKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLAS 1271
Query: 192 RNNSTEE-----------LQDL---AVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNN 237
+ ++ +QD+ L+ L E L+ + E K E+ L++
Sbjct: 1272 SSFEDQKIKAQMKKLKKLIQDMDPSIPLDSILNEPLDNCPDKESDINKLMLEVDYLKRQL 1331
Query: 238 DVQSLLKKENELL-------------QSKLDQLNSLQKKFESLEMENISLQEKITQWGI- 283
D+++ + E +S L + + KFE+ E SL++K+ +
Sbjct: 1332 DIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMPLR 1391
Query: 284 ----VRLDGKFKNPNDVI---TELNMLQREN----TFLLDTNSKLQIDFNQMSMLNDEMA 332
+ + KN + + E+ + EN L ++N KL + + A
Sbjct: 1392 DRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEA 1451
Query: 333 IERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPG- 391
+ QL L KD E++ + L+ ++QQK FE C
Sbjct: 1452 LLSEQLDRLQKDLESTERQKELLSSTIKQQK-QQFENCMDDLQGNELRLREHIHALKQAE 1510
Query: 392 -DQVNASNIIEGYKNQTED-----------------------------------LTNELK 415
D N ++IIE K Q + L+++L
Sbjct: 1511 EDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRVQDVKKILSDDLA 1570
Query: 416 RLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKIL 475
L E LS +D+ Q +I N L + + N E KI
Sbjct: 1571 HLKERLSAVEDRSQYTDEI-NRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKIS 1629
Query: 476 DLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSVYDRIKH 535
DL + +++++ +N K+ ++L EKE + T+ S+ +I
Sbjct: 1630 DLLKQLDHYTKVVEMLNN--------EKDAISLAEKELYQKYEALNTEC--ESLKGKIVS 1679
Query: 536 DMKLLEKEIFSANKKTTRLK 555
K+ ++ N+KT L+
Sbjct: 1680 LTKIKQELESDLNQKTDALQ 1699
Score = 54.3 bits (129), Expect = 6e-07
Identities = 78/393 (19%), Positives = 157/393 (39%), Gaps = 49/393 (12%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSM-------- 60
E ++ L ++LR R ++ + Q E ++ ++S E QNK + +
Sbjct: 1486 ENCMDDLQGNELRLR----EHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMER 1541
Query: 61 NELENALKDT-----------KILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLK 109
N+ + L++T KIL ++ LKE L + + + ++I SLK
Sbjct: 1542 NDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLK 1601
Query: 110 NEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQ 169
E NLK++ L +KL + N+ I + +++ ++ +N + I +
Sbjct: 1602 AETNLKKE-FATLKYKLETSTNDSEAKISDLLKQLDHYTKVVE----MLNNEKDAISLAE 1656
Query: 170 QELKEK-ENLISELRSVQTSASHRNNSTEELQD--------LAVLNKTLKEQLNYAKELE 220
+EL +K E L +E S++ +EL+ L + N L KE+
Sbjct: 1657 KELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEIT 1716
Query: 221 DMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQ 280
+ +K E +L+ + + EL+++ N + KF+ + +NI L E+
Sbjct: 1717 E-KIKYLEETLQLQMEQN-----SRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQT 1770
Query: 281 WGIVRLDGKFKNPNDVITELNMLQRENTFL-----LDTNSKLQIDFNQMSMLNDEMAIER 335
+ D + + N + L+ +N +L L+ L+ D M ++
Sbjct: 1771 LQKLNTDLQLQLKN-LHERLSDTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERA 1829
Query: 336 NQLLDLNKDYETSILNLKRLNHELEQQKLLSFE 368
+ L +T ++ L N ++ L +E
Sbjct: 1830 VEELQTKNSQQTDVIELANKNRSEFEEATLKYE 1862
>Hs5453642 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1233
Score = 59.3 bits (142), Expect = 2e-08
Identities = 70/328 (21%), Positives = 147/328 (44%), Gaps = 36/328 (10%)
Query: 55 KYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNL 114
+YDK E+ A +DT+ Y + E K KE+ L+ +VV + ++ L
Sbjct: 167 EYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQ-EKEEADRYQRLKDEVVRAQVQLQL 225
Query: 115 -----KEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQ 169
E I +L +L+SK E IE K ++ + L + + ++ K + E + ++
Sbjct: 226 FKLYHNEVEIEKLNKELASKNKE----IEKDKKRMDKVEDELKEKKKELGKMMREQQQIE 281
Query: 170 QELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKE-QLNYAKELEDMNLKQAT 228
+E+KEK++ +++ R A + N++ +++ L K+L+ Q +Y K DM+ +
Sbjct: 282 KEIKEKDSELNQKRPQYIKA--KENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKE 339
Query: 229 ELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL-------------EMENISLQ 275
L + + + +++E++ L + KK+ L E+E +
Sbjct: 340 MLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRD 399
Query: 276 EKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIER 335
+K Q RLD + + + ++ RE ++ N K +I+ + + + ++E
Sbjct: 400 QKADQ---DRLDLEERKKVETEAKIKQKLRE----IEENQK-RIEKLEEYITTSKQSLEE 451
Query: 336 NQLL--DLNKDYETSILNLKRLNHELEQ 361
+ L +L ++ E + + +N EL Q
Sbjct: 452 QKKLEGELTEEVEMAKRRIDEINKELNQ 479
Score = 52.0 bits (123), Expect = 3e-06
Identities = 71/310 (22%), Positives = 133/310 (42%), Gaps = 34/310 (10%)
Query: 2 SLTPQIKEKPLESLDADQLRR---RVLTLQYK---YTTLQNEYEISKLSSERETYSLQNK 55
++ + KE E +AD+ +R V+ Q + + NE EI KL+ E + + + +
Sbjct: 191 NIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIE 250
Query: 56 YDKS-MNELENALKDTKI----LYEENIKLKEELKSKDA-----------LPKEDEKIIT 99
DK M+++E+ LK+ K + E ++++E+K KD+ + I
Sbjct: 251 KDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIK 310
Query: 100 TLRTQVVSLKNEVNLKEQR---IVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHET 156
L SL+N ++R + EL ++ S + E M+ E + G L E
Sbjct: 311 KLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEEN 370
Query: 157 QINKHVEEIRYLQQELKEKENLISELRSV---QTSASHRNNSTE--ELQDLAVLNKTLKE 211
Q+ K+ R ++ K L EL Q + R + E +++ A + + L+E
Sbjct: 371 QVKKY---HRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 212 QLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLN-SLQKKFESLEME 270
K +E + T + L + ++ L +E E+ + ++D++N L + E L
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 271 NISLQEKITQ 280
I QE Q
Sbjct: 488 RIDRQESSRQ 497
>Hs20532997 [Z] KOG0161 Myosin class II heavy chain
Length = 975
Score = 59.3 bits (142), Expect = 2e-08
Identities = 82/360 (22%), Positives = 153/360 (41%), Gaps = 82/360 (22%)
Query: 44 SSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL------------------K 85
+S++E +L + K N E ++ + L EN L+EE+ K
Sbjct: 510 ASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEK 569
Query: 86 SKDALPKEDEKIITTL--------RTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAI 137
K + +E ++ TL R + L ++ L E + EL KLS K E+ N
Sbjct: 570 VKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAK-AELERKLSEKDEEIENFR 628
Query: 138 ESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHR--NNS 195
+ I+ + L +++ +E R L+++++E N + +Q S ++R + +
Sbjct: 629 RKQQCTIDSLQSSL---DSEAKSRIEVTR-LKKKMEEDLNEM----ELQLSCANRQVSEA 680
Query: 196 TEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLD 255
T+ L L + K L+ QL+ + +L + +LK+ ++ ++ N LLQS+L+
Sbjct: 681 TKSLGQLQIQIKDLQMQLDDSTQL-NSDLKEQV------------AVAERRNSLLQSELE 727
Query: 256 QLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNS 315
L SLQ++ E +S +E + + +N+ +NT LL
Sbjct: 728 DLRSLQEQTE--RGRRLSEEELL----------------EATERINLFYTQNTSLLSQKK 769
Query: 316 KLQIDFNQMSMLNDEM--------------AIERNQLLDLNKDYETSILNLKRLNHELEQ 361
KL+ D +M +E+ AIE L + K + +I +L+R +EQ
Sbjct: 770 KLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQ 829
>Hs12667788 [Z] KOG0161 Myosin class II heavy chain
Length = 1960
Score = 59.3 bits (142), Expect = 2e-08
Identities = 133/631 (21%), Positives = 235/631 (37%), Gaps = 102/631 (16%)
Query: 39 EISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKII 98
E ++ E E ++ K + N L L E ++L+E+L+++ L E E+
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE-- 901
Query: 99 TTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQI 158
L+ + K+Q + E+ H L ++ E + ++ E + + + E Q+
Sbjct: 902 ---------LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQL 952
Query: 159 NKHVEEIRYLQQE-------LK--EKENLISELRSVQTS----------ASHRNNSTEEL 199
+ + LQ E LK E+E +I E ++ + + A N TEE
Sbjct: 953 EEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE 1012
Query: 200 QDLAVLNKTLKEQLNYAKELED---MNLKQATELKKLRQNNDVQS--------------- 241
+ L K + +LE+ KQ EL+K R+ + S
Sbjct: 1013 EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIA 1072
Query: 242 -----LLKKENEL------LQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKF 290
L KKE EL ++ + Q N KK LE + LQE + R +
Sbjct: 1073 ELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE- 1131
Query: 291 KNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSIL 350
K D+ EL L+ E LD+ + Q S E+ I + L + K +E I
Sbjct: 1132 KQKRDLGEELEALKTELEDTLDSTAAQQ---ELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 351 NLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDL 410
+++ + + ++ E+ T + N + +N+ +L
Sbjct: 1189 EMRQKHSQAVEELAEQLEQ-------------------TKRVKANLEKAKQTLENERGEL 1229
Query: 411 TNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANIL 470
NE+K L + ++ K +K +L + +++ N +L
Sbjct: 1230 ANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL 1289
Query: 471 EQKILDLTSL-KEKKVRILQLRD-NPLLKEHYIRK----EKLALLEKENSDLLSGIETDA 524
Q + L K+ QL+D LL+E +K KL +E E + +E +
Sbjct: 1290 SQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEE- 1348
Query: 525 IPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKK--SLEFIEAVNSLLGFKLEFLAH 582
+ KH+ LEK+I + + + +K+ LE E V L LE L+
Sbjct: 1349 ------EEAKHN---LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
Query: 583 GKVKLVSCYQPNKYIIADLQS--NTLKSDLD 611
+ V+ Y + LQ + L DLD
Sbjct: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Score = 53.9 bits (128), Expect = 7e-07
Identities = 72/357 (20%), Positives = 153/357 (42%), Gaps = 44/357 (12%)
Query: 18 DQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMN---ELENALKDTKILY 74
DQL T+ KY ++ E E + SL +++M ELE K +
Sbjct: 1447 DQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEM 1506
Query: 75 EENIKLKEEL--------KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKL 126
E+ + K+++ KSK AL ++ E+ ++TQ+ L++E+ E + L L
Sbjct: 1507 EDLMSSKDDVGKSVHELEKSKRALEQQVEE----MKTQLEELEDELQATEDAKLRLEVNL 1562
Query: 127 SSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQ 186
+ + + ++ Q E + + V ++R ++ EL+++ + RS+
Sbjct: 1563 QAMKAQFERDLQGRD----------EQSEEKKKQLVRQVREMEAELEDER----KQRSMA 1608
Query: 187 TSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKE 246
+A R +L+DL + ++ A + D +KQ +L+ Q D L
Sbjct: 1609 VAA--RKKLEMDLKDL-------EAHIDSANKNRDEAIKQLRKLQA--QMKDCMRELDDT 1657
Query: 247 NELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRE 306
+ L Q +KK +S+E E I LQE++ + + + +++ E+ +
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ-QERDELADEIANSSGK 1716
Query: 307 NTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQK 363
L+ +L+ +++ L +E+ E+ +N + + L + ++N +L ++
Sbjct: 1717 GALALEEKRRLEA---RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Score = 50.8 bits (120), Expect = 6e-06
Identities = 125/624 (20%), Positives = 237/624 (37%), Gaps = 92/624 (14%)
Query: 16 DADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYE 75
D+ L ++ LQ + E ++ E E + + ++ + ALK + L
Sbjct: 1056 DSTDLSDQIAELQAQIA----ELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELES 1111
Query: 76 ENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELA--HKLSSKQNEV 133
+ +L+E+L+S+ A + EK L ++ +LK E+ E + A +L SK+ +
Sbjct: 1112 QISELQEDLESERASRNKAEKQKRDLGEELEALKTEL---EDTLDSTAAQQELRSKREQE 1168
Query: 134 TNAIESMKLEIEGSGNILHQHETQI----NKHVEEIRYLQQELKEKENLISEL-RSVQTS 188
N ++ LE E HE QI KH + + L ++L++ + + + L ++ QT
Sbjct: 1169 VNILKK-TLEEEAK-----THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 189 ASHRNNSTEELQ------------------DLAVLNKTLKEQLNYAKELEDMNLKQATEL 230
+ R E++ L L E EL D K EL
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 231 ---------------KKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQ 275
K + + ++S L+ ELLQ + Q SL K + +E E S +
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 276 EKITQWGIVR--LDGKFKNPNDVITELNMLQRENTFLLDT----NSKLQIDFNQMSMLND 329
E++ + + L+ + + + ++ ++ L+T KLQ D +S ++
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHE 1402
Query: 330 EMAIE-----------RNQLLDLNKDYE---TSILNLKRLNHELEQQKLLSFEECXXXXX 375
E + +L DL D + S NL++ + +Q LL+ E+
Sbjct: 1403 EKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQ--LLAEEKTISAKY 1460
Query: 376 XXXXXXXXXXXXXTPGDQVNASNIIE---GYKNQTEDLTNELKRLNEELSKTDDKIQKRR 432
++ + +E K + E L + + E+L + D + K
Sbjct: 1461 AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSV 1520
Query: 433 KITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRD 492
+ Q AT++ LE ++L ++K + R LQ RD
Sbjct: 1521 HELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE---VNLQAMKAQFERDLQGRD 1577
Query: 493 NPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSV----YDRIKHDMKLLEKEIFSAN 548
+EK L ++ ++ + +E + RS+ +++ D+K LE I SAN
Sbjct: 1578 EQ-------SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
Query: 549 KKTTRLKEVFNKKSLEFIEAVNSL 572
K + K + + + L
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMREL 1654
>Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2871
Score = 58.9 bits (141), Expect = 2e-08
Identities = 105/574 (18%), Positives = 240/574 (41%), Gaps = 62/574 (10%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSE--RETYSLQNKYDKSMNELENA 66
EK ++ + + R RVL + + E E++K+ + E +L+NKY+ +N +
Sbjct: 1161 EKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTT 1220
Query: 67 LKDTKILYEENIK-LKEELKSKDALPKEDEKIITTLRTQVVSLKNEV---NLKEQRIVEL 122
+K+ + E++ K L+ +L D L +E+ L+ ++V L + + + +R E
Sbjct: 1221 IKEISMQKEDDSKNLRNQL---DRLSRENR----DLKDEIVRLNDSILQATEQRRRAEEN 1273
Query: 123 AHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISEL 182
A + + +E+ + +++E++ ++ Q +H + + + +++K I L
Sbjct: 1274 ALQQKACGSEIMQKKQHLEIELK---QVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERL 1330
Query: 183 RSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSL 242
++ + R E N+ K + NY +E+ + + TE+ N ++
Sbjct: 1331 KAEFQEEAKRRWEYE--------NELSKVRNNYDEEIISLKNQFETEI------NITKTT 1376
Query: 243 LKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNM 302
+ ++L K + + + + ++L EN SL E+I + L +N V ++
Sbjct: 1377 I---HQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNT-LTQTTENLRRVEEDIQQ 1432
Query: 303 LQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLD----LNKDYETSILNLKRL-NH 357
+ + + +L+++ Q++ + E ++ Q LD +D I LK+L +
Sbjct: 1433 QKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDK 1492
Query: 358 ELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTN---EL 414
E +K L E +A+ I K Q ++LT +
Sbjct: 1493 ETNDRKCLEDENARLQRVQYDLQKANS----------SATETINKLKVQEQELTRLRIDY 1542
Query: 415 KRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKI 474
+R+++E + D I + + +L + + K LE+++
Sbjct: 1543 ERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKK----LEEEL 1598
Query: 475 LDL-TSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSG-IETDAIPRSVYDR 532
+ SLKE+ ++I L L++ I K++ ++ D+L G + + R
Sbjct: 1599 EGMRRSLKEQAIKITNLTQQ--LEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRR 1656
Query: 533 IKHDMKLLEKEIFSANK--KTTRLKEVFNKKSLE 564
+ +++ L +++ + K L+ +K++E
Sbjct: 1657 LSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIE 1690
Score = 57.8 bits (138), Expect = 5e-08
Identities = 114/596 (19%), Positives = 231/596 (38%), Gaps = 79/596 (13%)
Query: 37 EYEISKLSSERETYSLQNKYDKSMNELENALKD-TKILYEENIKLKEELKSKDALPKEDE 95
E E+ ++ +R + ++K +S+ E ++D K + + +EE K + E
Sbjct: 1292 EIELKQVMQQRSEDNARHK--QSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELS 1349
Query: 96 KIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNA----IESMKLEIEGSGNIL 151
K+ +++SLKN+ + H+L+ ++ E T+ I+++ E +
Sbjct: 1350 KVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEI 1409
Query: 152 HQHETQINKHVEEIRYLQQELKE-----------KENLISELRSVQTSASHRNNSTEELQ 200
+ + + + E +R +++++++ K+ L ELR Q + S Q
Sbjct: 1410 KRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELR--QVTQMRTEESVRYKQ 1467
Query: 201 DLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNND----VQSLLKKENELLQSKLDQ 256
L KT++++ + L+ + K+ + K L N VQ L+K N +++
Sbjct: 1468 SLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINK 1527
Query: 257 LNSLQKKFESLEM--ENISLQEKITQWGIVRLDGKFKN----PNDVITELNMLQRENTFL 310
L +++ L + E +S + + I R K V ELN L+R +
Sbjct: 1528 LKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASED 1587
Query: 311 LDTNSKLQIDFNQMSMLNDEMAIERNQLL---------------DLN----------KDY 345
KL+ + M E AI+ L DL ++
Sbjct: 1588 SCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREK 1647
Query: 346 ETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNI-IEGYK 404
+ + L+RL+ E+E + +E +N S I IE +
Sbjct: 1648 QRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 1707
Query: 405 NQTEDLTNELKRLNEEL--------------SKTD-DKIQKRRKITNDLGISYSQXXXXX 449
+ TE+LT E L EEL S+ D DK ++ + L IS ++
Sbjct: 1708 SLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQ 1767
Query: 450 XXXXXXXXXXXSATKNHANILEQKILDLTSLKEKK---VRILQLRDNPLLKEHYIRKEKL 506
+ + +Q + ++E K +++Q R++ L+K + ++K
Sbjct: 1768 GLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKA 1827
Query: 507 AL--LEKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNK 560
L LE E + S +E + V R++ + + ++ ++ + +R +E K
Sbjct: 1828 RLQRLEDELNRAKSTLEAET---RVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRK 1880
>Hs4502781_1 [Z] KOG0242 Kinesin-like protein
Length = 731
Score = 58.9 bits (141), Expect = 2e-08
Identities = 84/394 (21%), Positives = 170/394 (42%), Gaps = 51/394 (12%)
Query: 1 MSLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNK--YDK 58
M TP + E + + R+ ++ L+ + + E + ++ L+ K K
Sbjct: 329 MKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQK 388
Query: 59 SMNE-LENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQ 117
NE +EN + ++ ++ L++ELK+K ++ +T ++ +KN N +Q
Sbjct: 389 VQNEKIENLTR--MLVTSSSLTLQQELKAKR------KRRVTWCLGKINKMKNS-NYADQ 439
Query: 118 -----RIVELAHKLS------------SKQNEVTNAIESMKLEIEGSGNILHQHETQINK 160
I HKLS S+ + +N ++++ EIE + ++ I
Sbjct: 440 FNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLS-EIEWNPATKLLNQENIES 498
Query: 161 HVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDL----AVLNKTLKEQ-LNY 215
+ +R + +NL+ + ++T +E DL A+ KT K+Q +
Sbjct: 499 ELNSLR------ADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQL 552
Query: 216 AKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQ 275
E+ NLK + +++ N D+++ L + ELL+ K DQ+ LQ+ +S ++ENI +
Sbjct: 553 IHEIS--NLKNLVKHREV-YNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMD 609
Query: 276 EKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIER 335
+ I + D T +RE+ FL N +L+ E+A
Sbjct: 610 LSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMK-------ELATTY 662
Query: 336 NQLLDLNKDYETSILNLKRLNHELEQQKLLSFEE 369
Q+ + + Y++ + K++ +LE++ +F E
Sbjct: 663 KQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNE 696
>Hs7705348 [Z] KOG0247 Kinesin-like protein
Length = 1780
Score = 58.5 bits (140), Expect = 3e-08
Identities = 78/320 (24%), Positives = 141/320 (43%), Gaps = 55/320 (17%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL 67
K K LE++ Q R + + + L+ E I KL ER Q L++++
Sbjct: 1122 KIKELETILETQKVERSHSAKLEQDILEKESIILKL--ERNLKEFQE-------HLQDSV 1172
Query: 68 KDTKILYEENIKLKEE----------LKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQ 117
K+TK L + +KLKEE +K L +E+E+ T R + LK E++
Sbjct: 1173 KNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEE---TNRQETEKLKEELSASSA 1229
Query: 118 RIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKEN 177
R L L K+ + + E L + QI + +E+ ++ E K
Sbjct: 1230 RTQNLKADLQRKEEDYADLKEK-----------LTDAKKQIKQVQKEVSVMRDEDKLLRI 1278
Query: 178 LISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLN----------YAKELEDMNLKQA 227
I+EL +N ++EL + LKEQLN Y + +D+N+K+
Sbjct: 1279 KINELE------KKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1332
Query: 228 TELKKLRQNNDVQSLLK-KENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRL 286
++ +R + Q + +++++L++KL+++ L + E + + L+ K Q R
Sbjct: 1333 I-IEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ----RS 1387
Query: 287 DGKFKNPNDVITELNMLQRE 306
+ + +N DV+ +L LQ E
Sbjct: 1388 NKEHENNTDVLGKLTNLQDE 1407
Score = 53.5 bits (127), Expect = 1e-06
Identities = 73/360 (20%), Positives = 145/360 (40%), Gaps = 31/360 (8%)
Query: 7 IKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENA 66
+KE L+ + QL + +++ + E E ++ +ET L+ + S +N
Sbjct: 1180 VKELKLKE-EITQLTNNLQDMKHLLQLKEEEEETNR----QETEKLKEELSASSARTQNL 1234
Query: 67 LKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKL 126
D + E+ LKE+L K+ +K ++ +R + L+ ++N E++ + + +L
Sbjct: 1235 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 1294
Query: 127 SSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQ 186
KQ + E + + ++ + +++ ++L KE +I ++R
Sbjct: 1295 DMKQRTIQQLKEQL-------------NNQKVEEAIQQYERACKDLNVKEKIIEDMR--M 1339
Query: 187 TSASHRNNSTEELQDLAVLNKTLKEQLNYAKELE-------DMNLKQATELKKLRQNN-D 238
T E+ Q VL L+E A ELE D+ K K +NN D
Sbjct: 1340 TLEEQEQTQVEQDQ---VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTD 1396
Query: 239 VQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVIT 298
V L + LQ + N+ +KK+ +M I+ ++ + ++
Sbjct: 1397 VLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFK 1456
Query: 299 ELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHE 358
+ N ++ L + +S LQ + L + I+ L+ N + I LKR+ E
Sbjct: 1457 QQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISE 1516
>CE09197 [Z] KOG0161 Myosin class II heavy chain
Length = 872
Score = 58.5 bits (140), Expect = 3e-08
Identities = 105/544 (19%), Positives = 230/544 (41%), Gaps = 77/544 (14%)
Query: 35 QNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKED 94
+ E E+SKL E L++ + +MN L +D+ + Y++ I E+L+ K+A +
Sbjct: 93 KREGELSKLRKLLEESQLES--EDAMNVLRKKHQDSCLDYQDQI---EQLQKKNAKIDRE 147
Query: 95 EKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQH 154
+ + ++ + +++ + + A + ++ NE+ N +E +
Sbjct: 148 RQRVQHEVIELTATIDQLQKDKHTAEKAAERFEAQANELANKVEDL-------------- 193
Query: 155 ETQINKHVEEIRYLQQELKEKEN-LISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQL 213
NKHV ++ +Q L+ + N L+ E+ + +L +L + TL +QL
Sbjct: 194 ----NKHVNDLAQQRQRLQAENNDLLKEVHDQKV----------QLDNLQHVKYTLAQQL 239
Query: 214 NYAKE-LEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFE-SLEMEN 271
A+ LED +++ +L Q ++ E + +++ LD+ + + E L + N
Sbjct: 240 EEARRRLEDAERERSQLQSQLHQ-------VQLELDSVRTALDEESIARSDAEHKLNLAN 292
Query: 272 ISLQEKITQWGIVRLDGKFKNPNDVITELN--MLQRENTFLLDTNSKLQIDFNQMSMLND 329
+ITQW + D + ++ + +L MLQ++ + +++I ++S L
Sbjct: 293 T----EITQWKS-KFDAEVALHHEEVEDLRKKMLQKQAEY----EEQIEIMLQKISQL-- 341
Query: 330 EMAIERNQ------LLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXX 383
E A R Q ++DL K T L L+R +LE+Q + +
Sbjct: 342 EKAKSRLQSEVEVLIVDLEKAQNTIAL-LERAREQLERQ--VGELKVRIDEITVELEAAQ 398
Query: 384 XXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYS 443
+ ++ E Q E L E K+L++EL + + + + ++L + +
Sbjct: 399 RELRAVNAELQKMKHLYEKAVEQKEALARENKKLHDELHEAKEALADANRKLHELDLENA 458
Query: 444 QXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRK 503
+ + ++ N ++ + +L +L+ + R LQ ++ + +RK
Sbjct: 459 RLAGEIRELQTALKEADAQRRDAENRAQRALAELQALRIEMERRLQEKEEEM---EALRK 515
Query: 504 EKLALLEKENSDLLSGI-ETDAIPRSVYDRIKH----DMKLLEKEIFSANKKTTRLKEVF 558
L+ E L++ + + +A +S R+K ++ LE + + N+ ++
Sbjct: 516 N----LQFEIDRLIAALADAEARMKSEISRLKKKYQAEIAELEMTVDNLNRANIEAQKTI 571
Query: 559 NKKS 562
K+S
Sbjct: 572 KKQS 575
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 58.2 bits (139), Expect = 4e-08
Identities = 128/644 (19%), Positives = 250/644 (37%), Gaps = 120/644 (18%)
Query: 31 YTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSK--- 87
+T + +S S RE S+Q++ ++ E++ L + ++ KEEL+ K
Sbjct: 413 FTYYRENLLLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKS 472
Query: 88 -----DALPKEDEKIITTLRTQVVS----LKNEVNLKEQRIVELAHKL---SSKQNEVTN 135
+ KE E+ I TLR V S L+ E L + + E K + K+ + N
Sbjct: 473 VNTRLEKTAKELEEEI-TLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLEN 531
Query: 136 AIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLI-------SELRSVQTS 188
+ S+K ++E L + E++ LQ++L E L+ + LR Q
Sbjct: 532 DVNSLKDQLED----LKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAE 587
Query: 189 ASHR----NNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQN------ND 238
+S + ++ +LQD L +T K +L E E +NL+ A E ++ + ND
Sbjct: 588 SSKQIQQLESNNRDLQDKNCLLETAKLKL----EKEFINLQSALESERRDRTHGSEIIND 643
Query: 239 VQSLL------KKENELLQSKLD-QLNSLQKKFESLEME------NISLQEKITQWGIVR 285
+Q + K ++L +K++ + LQ++F LE E +++ Q K+ Q + +
Sbjct: 644 LQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQ 703
Query: 286 LDGKFK--------------------------NPNDVITELNMLQRENTFLLDTN---SK 316
+ + K ++ E + Q+ LL+ S
Sbjct: 704 EEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSL 763
Query: 317 LQIDFNQMSMLNDEMAIE--------RNQLLDLNKDYETSILNLKRLNHELEQQKLLSFE 368
L D Q +E+ + RN L + ++ + L L + +Q L
Sbjct: 764 LDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMS 823
Query: 369 ECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTED--------------LTNEL 414
E + +G + +D EL
Sbjct: 824 EKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVREL 883
Query: 415 KRLNEELSKTDDKI-QKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQK 473
K EE +K ++ QK++++ ++ +Q A + ++++ ++K
Sbjct: 884 KEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEK 943
Query: 474 ILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGI-----ETDAIPRS 528
I +KE +++ + R L E + +A LE+ N L S + E + +
Sbjct: 944 I-----MKELEIKEMMARHKQELTE---KDATIASLEETNRTLTSDVANLANEKEELNNK 995
Query: 529 VYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSL 572
+ D + +L ++EI +A K K++ +++L+ +AVN L
Sbjct: 996 LKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLK-TQAVNKL 1038
Score = 57.8 bits (138), Expect = 5e-08
Identities = 85/369 (23%), Positives = 162/369 (43%), Gaps = 68/369 (18%)
Query: 23 RVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKI-LYEENIKLK 81
R LTL+ + T + + L + + + +K + + N L + K+ L ++N +L+
Sbjct: 790 RNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELR 849
Query: 82 EELKSKDALPKE-------DEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVT 134
+E + D KE ++ T +TQV LK E K +L +L K+ E+
Sbjct: 850 KERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEK----TKLGKELQQKKQELQ 905
Query: 135 NAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNN 194
+ +S+ ++E + + Q+ + + E +Y E KE ++ EL + A H+
Sbjct: 906 DERDSLAAQLEIT--LTKADSEQLARSIAEEQYSDLE---KEKIMKELEIKEMMARHKQE 960
Query: 195 STEELQDLAVL---NKTLKEQL-NYAKELEDMNLK------QATELK------------- 231
TE+ +A L N+TL + N A E E++N K Q + LK
Sbjct: 961 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF 1020
Query: 232 ----------KLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQW 281
K + N + ++ ++ + + + +K+ L ME S +EK+TQ
Sbjct: 1021 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ 1080
Query: 282 GIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIE--RNQLL 339
I K++ ELN +Q + + S+++I+ QM++ + + IE R+QL
Sbjct: 1081 MI-----KYQK------ELNEMQAQ----IAEESQIRIEL-QMTLDSKDSDIEQLRSQLQ 1124
Query: 340 DLNKDYETS 348
L+ ++S
Sbjct: 1125 ALHIGLDSS 1133
Score = 52.4 bits (124), Expect = 2e-06
Identities = 90/414 (21%), Positives = 166/414 (39%), Gaps = 61/414 (14%)
Query: 27 LQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELK- 85
LQ ++T L+ E ++ TY L+ +S+ + E K TK + K+ E ++
Sbjct: 672 LQERFTDLEKEKSNMEIDM---TYQLK-VIQQSLEQEEAEHKATKARLADKNKIYESIEE 727
Query: 86 SKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIE 145
+K KE EK + RT ++N + E+R L L Q ++ ++ + E
Sbjct: 728 AKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNE 787
Query: 146 GSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVL 205
N+ + E + K Q +LK + T+++ L +
Sbjct: 788 DVRNLTLKIEQETQKRC----LTQNDLKMQ--------------------TQQVNTLKMS 823
Query: 206 NKTLKEQLNYAKELEDMNL-KQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKF 264
K LK++ N+ E++ MNL KQ EL+K RQ+ D Q ++ DQL + Q
Sbjct: 824 EKQLKQENNHLMEMK-MNLEKQNAELRKERQDADGQ---------MKELQDQLEAEQYFS 873
Query: 265 ESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQM 324
+ + L+E+ + K K ++ + LQ E L ++L+I +
Sbjct: 874 TLYKTQVRELKEECEE--------KTKLGKELQQKKQELQDERDSLA---AQLEITLTKA 922
Query: 325 SMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXX 384
+I Q DL K+ ++ ELE +++++ +
Sbjct: 923 DSEQLARSIAEEQYSDLEKE---------KIMKELEIKEMMARHKQELTEKDATIASLEE 973
Query: 385 XXXXTPGDQVNASNIIEGYKNQTEDLTNELKRL-NEELSKTDDKIQKRRKITND 437
D N +N E N+ +D+ +L RL +EE+S K Q +++ +
Sbjct: 974 TNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTE 1027
>Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2649
Score = 58.2 bits (139), Expect = 4e-08
Identities = 77/407 (18%), Positives = 169/407 (40%), Gaps = 87/407 (21%)
Query: 22 RRVLTLQYKYTTLQNEYEISKLS-SERETYSLQNKYDKSMNELENALKDTKILYEENIKL 80
+ + L + + ++E E+ +L +R++ L+ +++KS +L +K K ++ +L
Sbjct: 1499 KNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRL 1558
Query: 81 KEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESM 140
EEL+ + + ++ + L Q NE L QRI + + ++ + E++
Sbjct: 1559 NEELEKSNECAEMLKQKVEELTRQ----NNETKLMMQRIQAESENIVLEKQTIQQRCEAL 1614
Query: 141 KLEIEGSGNILHQHETQINKHVE-------EIRYLQQELKEKENLISELRSV-------- 185
K++ +G + L ++K + +I+ L+++L + +NL+SE +
Sbjct: 1615 KIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIII 1674
Query: 186 -------------------------------QTSASHRNNSTEELQDLAVLNKTLKEQLN 214
Q NN +++QD L KT++EQ+
Sbjct: 1675 QNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHL-KTIEEQMT 1733
Query: 215 YAKEL----EDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEME 270
+ K + E KQ+ E + + ++S + EN++ +LD F SL+ E
Sbjct: 1734 HRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLD--------FVSLQQE 1785
Query: 271 NISLQE--KITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLN 328
N QE K+ + I L+ + + + + + ++ + + + L
Sbjct: 1786 NSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANH-------------YQKCQKLE 1832
Query: 329 DEMAIERNQLLDLNKDYETSILNLKRLNHEL-----EQQKLLSFEEC 370
DE+ ++ ++ +L + + I K H+L E QK + ++C
Sbjct: 1833 DELIAQKREVENLKQKMDQQI---KEHEHQLVLLQCEIQKKSTAKDC 1876
Score = 57.4 bits (137), Expect = 7e-08
Identities = 109/560 (19%), Positives = 223/560 (39%), Gaps = 99/560 (17%)
Query: 1 MSLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYE---ISKLSSERETYSLQNKYD 57
++ Q+ EK L+ +L R + +YT +N I++ +S R LQ ++D
Sbjct: 1298 LAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHD 1357
Query: 58 KSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQ 117
K E +LK+++ A ++ E+ + L ++ +L+ E E+
Sbjct: 1358 KQKAE----------------ELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEE 1401
Query: 118 RIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKEN 177
+ A L K +E N + +KLE+E K E Y QQ
Sbjct: 1402 K----ARLLKDKLDETNNTLRCLKLELE-------------RKDQAEKGYSQQ------- 1437
Query: 178 LISEL-RSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQN 236
+ EL R + + + +E DL + + NY ELE +N E KL++
Sbjct: 1438 -LRELGRQLNQTTGKAEEAMQEASDLKKIKR------NYQLELESLN----HEKGKLQRE 1486
Query: 237 NDVQSLLKKENELLQSKLDQLNSLQKKF-ESLEMENISLQEKITQWGIVRLDGKFKNPND 295
D + + + + + + LNS F + E+E + + ++ + L +F+ ++
Sbjct: 1487 VD---RITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSD----HLKEQFEKSHE 1539
Query: 296 VITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRL 355
+ + ++EN N K+Q ++ N+ + + ++ +L + + L ++R+
Sbjct: 1540 QLLQNIKAEKEN------NDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRI 1593
Query: 356 NHELEQ---QKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTE-DLT 411
E E +K + C DQ+ ++N + +TE D
Sbjct: 1594 QAESENIVLEKQTIQQRCEALKIQADGFK----------DQLRSTNEHLHKQTKTEQDFQ 1643
Query: 412 NELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILE 471
++K L E+L+K+ + + + ++ + I +A+K E
Sbjct: 1644 RKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQN----TKKEVRNLNAELNASKEEKRRGE 1699
Query: 472 QKI-LDLTSLKEKKVRILQLRDNPLLK--EHYIRKEKLALLEKENSDLLSGIETDAIPRS 528
QK+ L ++E R+ +++D LK E + K+ L ++E+ +S
Sbjct: 1700 QKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESG---------KFKQS 1750
Query: 529 VYDRIKHDMKLLEKEIFSAN 548
+ K KL+E ++ + N
Sbjct: 1751 AEEFRKKMEKLMESKVITEN 1770
>Hs11128045_1 [TU] KOG1029 Endocytic adaptor protein intersectin
Length = 1177
Score = 58.2 bits (139), Expect = 4e-08
Identities = 59/279 (21%), Positives = 133/279 (47%), Gaps = 22/279 (7%)
Query: 21 RRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENAL-KDTKILYEENIK 79
+RR ++ + + + + K ER+ LQ + K ELE L K ++ + +
Sbjct: 391 KRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEE 450
Query: 80 LKEELKSKDALPKEDEKI--ITTLRTQVVSLKNEVNLKEQRIVELAHK----------LS 127
+++++ ++A +E E+ + R + L N+ N +++ IV L K L+
Sbjct: 451 RRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALN 510
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKEN----LISELR 183
K +++ ++ ++L+ + L + Q + + EI+ LQQEL+E +N L+ E +
Sbjct: 511 GKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQ 570
Query: 184 SVQTSASHRNNSTEELQDLAVLNKTL--KEQL--NYAKELEDMNLKQATELKKLRQNNDV 239
+ + S +++L+K KE+L ++L+ + + A++L ++ N+
Sbjct: 571 LLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQ 630
Query: 240 QSLLKKENELLQSKLDQLNSLQK-KFESLEMENISLQEK 277
L++ Q L+QL +++ K + +E + + L +K
Sbjct: 631 LKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQK 669
>Hs4505541 [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 962
Score = 57.8 bits (138), Expect = 5e-08
Identities = 79/360 (21%), Positives = 165/360 (44%), Gaps = 51/360 (14%)
Query: 25 LTLQYKYTTLQNEYE--ISK-LSSERETYSLQNKYDKSMNELENALKDTK-ILYEENIKL 80
+ +++T L E E I+K + E + + K++ + +N + K ++ E++++L
Sbjct: 607 MIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQL 666
Query: 81 KEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESM 140
+E + L ++E++ T + QV ++ + ++L K + Q + +
Sbjct: 667 EELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLG-KDNQHQGSYSEGAQMN 725
Query: 141 KLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNS----- 195
++ E G + + E + K +E+ LQ +L EK+++I ++S QTS ++ +S
Sbjct: 726 GIQPEEIGRL--REEIEELKRNQEL--LQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSA 781
Query: 196 --TEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSK 253
+E++ +L TLK QLN Q+ E+ KL+ + Q LL+K +S
Sbjct: 782 RDSEQVAELKQELATLKSQLN----------SQSVEITKLQ--TEKQELLQKTEAFAKSV 829
Query: 254 LDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFL--- 310
+Q + E++ + E RL + ++ E+ L E T +
Sbjct: 830 -----EVQGETETIIATKTTDVEG-------RLSALLQETKELKNEIKALSEERTAIKEQ 877
Query: 311 LDTNSK----LQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKR----LNHELEQQ 362
LD+++ LQ + +++ + + E++ LL L D + IL+LK L H +E++
Sbjct: 878 LDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEE 937
>Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 948
Score = 57.4 bits (137), Expect = 7e-08
Identities = 111/579 (19%), Positives = 233/579 (40%), Gaps = 131/579 (22%)
Query: 23 RVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKE 82
++ +++ L+ E ++ K + T + ++ M ++E +K + + ++K+
Sbjct: 390 KISSMERGLRDLEEEIQMLKSNGALST----EEREEEMKQMEVYRSHSKFMKNKIGQVKQ 445
Query: 83 ELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKL 142
EL KD + L+T++ +L N+ + +Q I L L++K+
Sbjct: 446 ELSRKDT-------ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAA-------- 490
Query: 143 EIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDL 202
IL E+ L+ L+EKE ++ N T+++QD+
Sbjct: 491 -------ILQ----------TEVDALRLRLEEKETML-------------NKKTKQIQDM 520
Query: 203 AVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQK 262
A +E+ A E+ D LK ++K+ R+ N +Q ++ E L+ K Q++SL++
Sbjct: 521 A------EEKGTQAGEIHD--LKDMLDVKE-RKVNVLQKKIENLQEQLRDKEKQMSSLKE 571
Query: 263 KFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFN 322
+ +SL+ + + +T L K + + + + +RE +D K D
Sbjct: 572 RVKSLQADTTNTDTALTTLE-EALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK 630
Query: 323 Q-MSMLNDEMAIERNQLLDLNKDYETSILN--------LKRLNHELEQQKLLSFEECXXX 373
+ +S+L +++ + LLDL K++ +S+ + LK L LEQ+K EEC
Sbjct: 631 EKVSLLQGDLSEKEASLLDL-KEHASSLASSGLKKDSRLKTLEIALEQKK----EECLKM 685
Query: 374 XXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRK 433
+ ++ + L E+ R +E SK ++ + +
Sbjct: 686 ESQLKKAHEAALEARASPEM----------SDRIQHLEREITRYKDESSKAQAEVDRLLE 735
Query: 434 ITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDN 493
I ++ +N N ++KI +L SL ++V+ +
Sbjct: 736 ILKEV-------------------------ENEKNDKDKKIAELESLTSRQVKDQNKKVA 770
Query: 494 PLLKEHYIRKEKLALL-------EKENSDLLSGIETDAIPRSVYDRIKHDMK-------- 538
L + + K+K A + E +D ++ + + ++ +++K +++
Sbjct: 771 NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQVEELLMAM-EKVKQELESMKAKLSS 829
Query: 539 ----LLEKEIFSANKKTTR---LKEVFNKKSLEFIEAVN 570
L EKE N + R L+EV K + A++
Sbjct: 830 TQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAIS 868
Score = 53.1 bits (126), Expect = 1e-06
Identities = 85/369 (23%), Positives = 156/369 (42%), Gaps = 60/369 (16%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYT---TLQNEYEISKLSSERETYSLQNKYDKS----M 60
KEK + SL + RV +LQ T T E + ER L+ + D+
Sbjct: 562 KEKQMSSL-----KERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQ 616
Query: 61 NELENALKDTKILYEENIKLKEELKSKDA-----------LPKEDEKIITTLRTQVVSL- 108
E++N KD K L E+ L+ +L K+A L K + L+T ++L
Sbjct: 617 EEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 676
Query: 109 -KNEVNLKEQRIVELAHKLSSKQN---EVTNAIESMKLEIEGSGNILHQHETQINKHVEE 164
K E LK + ++ AH+ + + E+++ I+ ++ EI + + + ++++ +E
Sbjct: 677 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEI 736
Query: 165 IRYLQQELKEKENLISELRSVQT-SASHRNNSTEELQDLAVLNKTLKEQ-LNYAKELEDM 222
++ ++ E +K+ I+EL S+ + +N L+ + K Q L A+ ED
Sbjct: 737 LKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDN 796
Query: 223 ------------------NLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKF 264
+KQ E K + ++ QSL +KE L + ++ L+
Sbjct: 797 LNDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLE--- 853
Query: 265 ESLEMEN----ISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQID 320
E LEM+ ++ EK ++ L K + E+ L+RE L+ Q
Sbjct: 854 EVLEMKQEALLAAISEKDANIALLELSSSKKKTQE---EVAALKREKDRLV--QQLKQQT 908
Query: 321 FNQMSMLND 329
N+M ++ D
Sbjct: 909 QNRMKLMAD 917
>YPR141c [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 729
Score = 57.0 bits (136), Expect = 9e-08
Identities = 67/336 (19%), Positives = 156/336 (45%), Gaps = 32/336 (9%)
Query: 45 SERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKI------I 98
+++ + + Y +++NEL + IL+E+ L KD L + EKI
Sbjct: 87 NQKSNSGVTSFYKENVNELN---RTQAILFEKKATLD---LLKDELTETKEKINAVNLKF 140
Query: 99 TTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSG-NILHQHETQ 157
TLR + + ++ ++NLK ++ + + SK+ + E ++ S L Q E +
Sbjct: 141 ETLREEKIKIEQQLNLKNNELISIKEEFLSKKQFMNEGHEIHLKQLAASNKKELKQMENE 200
Query: 158 INKHVEEIRY--LQQELKEKENLISELRSVQTSASHRNNSTEE-LQDLAVLNKTLKE--- 211
+E++++ ++Q E+ +L+ ++ V+ + ++ +E L D+ + KE
Sbjct: 201 YKTKIEKLKFMKIKQFENERASLLDKIEEVRNKITMNPSTLQEMLNDVEQKHMLEKEEWL 260
Query: 212 ---QLNYAKELEDMNLKQATELKKLRQ--NNDVQSLLKKENELLQSKLDQLNSLQKKFES 266
Q + K++E +N K E++ +++ N ++ L ++ +LL K + +++ K +
Sbjct: 261 TEYQSQWKKDIE-LNNKHMQEIESIKKEIENTLKPELAEKKKLLTEKRNAYEAIKVKVKE 319
Query: 267 LEMENISLQEKITQWGIVRLD--GKFKNPNDVITELNMLQRE-NTFLLDTNSKLQIDFNQ 323
E E L++++ L+ K K + I + + +E N L+ + + N+
Sbjct: 320 KEEETTRLRDEVALKQKTNLETLEKIKELEEYIKDTELGMKELNEILIKEETVRRTLHNE 379
Query: 324 MSMLNDEMAIE---RNQLLDLNKDYETSILNLKRLN 356
+ L + + R L +L ++ +TS++N+ +
Sbjct: 380 LQELRGNIRVYCRIRPALKNL-ENSDTSLINVNEFD 414
>CE03665 [Z] KOG0161 Myosin class II heavy chain
Length = 1968
Score = 57.0 bits (136), Expect = 9e-08
Identities = 74/368 (20%), Positives = 149/368 (40%), Gaps = 46/368 (12%)
Query: 35 QNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKED 94
Q + ISKL+ ER+ QNK K +L+ A + + KL + L+ + + +
Sbjct: 1000 QQDENISKLNKERKNQEEQNK--KLTEDLQAAEEQNLAANKLKAKLMQSLEDSEQTMERE 1057
Query: 95 EKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQH 154
++ + + E+ + ++ + EL + +++ NA+ + E+ G L
Sbjct: 1058 KRNRADMDKNKRKAEGELKIAQETLEEL----NKSKSDAENALRRKETELHTLGMKLEDE 1113
Query: 155 ETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHR--------NNSTEELQDLAVLN 206
+ + K + I+ + +K+ + +++ + + A + TE+L+D A
Sbjct: 1114 QAAVAKLQKGIQQDEARVKDLHDQLADEKDARQRADRSRADQQAEYDELTEQLEDQARAT 1173
Query: 207 KTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFES 266
E L K+ E L++ E L+ + L KK ++ +Q DQ+ LQK+
Sbjct: 1174 AAQIE-LGKKKDAELTKLRRDLEESGLKFGEQLTVLKKKGSDAIQELSDQIEQLQKQKGR 1232
Query: 267 LEMENISL--------------------QEKITQWGIVRL-------DGKFKNPNDVITE 299
+E E + QE+I + VRL D + + D ++
Sbjct: 1233 IEKEKGHMQREFDESSAALDQEAKLRADQERIAKGYEVRLLELRLKADEQSRQLQDFVSS 1292
Query: 300 LNMLQRENTFLL----DTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRL 355
L EN+ L + +K+Q ++E+ + Q + +++ + K L
Sbjct: 1293 KGRLNSENSDLARQVEELEAKIQAANRLKLQFSNELDHAKRQAEEESRERQNLSNLSKNL 1352
Query: 356 NHELEQQK 363
ELEQ K
Sbjct: 1353 ARELEQLK 1360
>Hs4504949 [W] KOG1836 Extracellular matrix glycoprotein Laminin subunits
alpha and gamma
Length = 1816
Score = 56.6 bits (135), Expect = 1e-07
Identities = 80/344 (23%), Positives = 143/344 (41%), Gaps = 68/344 (19%)
Query: 41 SKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITT 100
+KLS Y+L+ +N EN +K EE ++ + + K L +++
Sbjct: 316 TKLSERENQYALRKI---QINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESM---- 368
Query: 101 LRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINK 160
+ +N Q +VE AH + K E+ N + E E S + + K
Sbjct: 369 ---------DTINHASQ-LVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418
Query: 161 HVEEIR-----YLQQELKEKE-NLISELRSVQTSASHRNNST--------EELQD----L 202
+EEIR + Q+EL ++E + EL S S +N T E+L D L
Sbjct: 419 MLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKL 478
Query: 203 AVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLN-SLQ 261
+ L + L + LN+ ++ EDMN A RQ + +K+ E ++ +++ +N SL
Sbjct: 479 SDLQEALDQALNHVRDAEDMNRATAA-----RQRDH-----EKQQERVREQMEVVNMSLS 528
Query: 262 KKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDF 321
+SL ++L E LD KN + + E++ S+LQ+
Sbjct: 529 TSADSLTTPRLTLSE---------LDDIIKNASGIYAEID----------GAKSELQVKL 569
Query: 322 NQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLL 365
+ +S L+ ++ + +D +D + L R H + L+
Sbjct: 570 SNLSNLSHDLV---QEAIDHAQDLQQEANELSRKLHSSDMNGLV 610
>CE08691 [U] KOG0999 Microtubule-associated protein Bicaudal-D
Length = 869
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/222 (22%), Positives = 102/222 (45%), Gaps = 23/222 (10%)
Query: 61 NELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIV 120
+ELE +D IL E+ + KE++ E + L ++ ++ E++L I
Sbjct: 4 SELEKLRQDIAILTEKYEQAKEDIHKAANAGLELLRQKEDLEKRLAEMQAELDLARTEID 63
Query: 121 ELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLIS 180
+ L+ +++ + S E+E ++L + + ++++ I L+ +LK+KE ++
Sbjct: 64 KTNQTLAEYRSQHQRSTRS---ELENEESLLEESSAKEEEYLQRIAKLEADLKKKEQELA 120
Query: 181 ELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNN--- 237
E + ++L + K ++++ LED K ELK+ ++
Sbjct: 121 EKK----------------EELESIEKKHSKEIDSGAALEDERRKLRAELKETKEREQRL 164
Query: 238 -DVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKI 278
S L++EN LQ + L Q ++ESL ++N L+E I
Sbjct: 165 ISEYSELEEENIGLQKTVANLRGSQVEYESLRIDNNRLEETI 206
>7295043 [Z] KOG0161 Myosin class II heavy chain
Length = 879
Score = 56.6 bits (135), Expect = 1e-07
Identities = 116/592 (19%), Positives = 230/592 (38%), Gaps = 73/592 (12%)
Query: 2 SLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMN 61
S+ Q++E+ +D L R+++ T+ QN++ + E ++ KY +
Sbjct: 271 SVRNQLEEESEARID---LERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRIT 327
Query: 62 ELENALKDTKILYEENIKLKEELKSK-----------DALPKEDEKIITTLRTQVVSLKN 110
ELE ++ + K+K L S+ + +E K + TL V LK+
Sbjct: 328 ELEEHIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKS 387
Query: 111 --------------EVNLKEQRIVELAHKLSS-KQNEVTNAIESMKLEIEGSGNILHQHE 155
++ K +V H+L K N E+ KL G+ LH+ +
Sbjct: 388 RLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRENKKL-----GDDLHEAK 442
Query: 156 TQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEEL-QDLAVLNKTLKEQLN 214
IN+ + L+ EL+ EN EL + A + E+ Q LA
Sbjct: 443 GAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAA---------- 492
Query: 215 YAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISL 274
D N + ++L + ++ ++K+ + +++QLN+ + E+ ++
Sbjct: 493 ------DFNQYRHDAERRLAEKDEEIEAIRKQTSI---EIEQLNARVIEAETRLKTEVTR 543
Query: 275 QEKITQWGIVRLDGKFKNPNDVITEL-NMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAI 333
+K Q I L+ N +L ++++++ L + + + Q+ D+ A+
Sbjct: 544 IKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAV 603
Query: 334 ERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQ 393
+ +L LN + E +L N ++ L +EE + +Q
Sbjct: 604 AQRRLAGLNGELEEVRSHLDSAN-RAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQ 662
Query: 394 VNASNIIEGYKNQTEDL----------TNELKRLNEELSKTDDKIQKRRKITNDLGISYS 443
S + Y+ +++L ELK + E++ + ++I K I L +
Sbjct: 663 -ELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEV--- 718
Query: 444 QXXXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRK 503
+ + +K + LE +I DL E++ R L K+ K
Sbjct: 719 EVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVK 778
Query: 504 EKLALLEKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLK 555
E L E++ +L+ + DA+ +S + +L E+E S + TTR++
Sbjct: 779 EVLVQCEEDQKNLI--LLQDALDKSTAKINIYRRQLSEQEGVS-QQTTTRVR 827
>7294128 [S] KOG0992 Uncharacterized conserved protein
Length = 776
Score = 56.6 bits (135), Expect = 1e-07
Identities = 107/543 (19%), Positives = 244/543 (44%), Gaps = 70/543 (12%)
Query: 34 LQNEYEISKLSSERETYSLQNK----YDKSMNELENALKDTKILYEENIKLKEELKSKDA 89
++N + S R++ ++ K D + +E L+++ + E N D
Sbjct: 12 MENPASVENGDSGRDSNHIEGKAIGDVDMKADSIEQQLEESDVKTESN---------GDQ 62
Query: 90 LPKEDE-KIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSG 148
L +DE KI L+ V+ +V ++E+ + S + + A E +K E++ +
Sbjct: 63 LTDQDEGKIEQDLKAAVLE---QVPIEEEGL--------SLRFKDLQAQEKVK-ELQQTP 110
Query: 149 NILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQ-DLAVLNK 207
+ Q++ I HV + L+++ + E + +LR TS ++N +Q + A+L K
Sbjct: 111 SQPPQND--ILSHVHCLAQLEEQRRNYEQQLEQLR---TSNVQKDNMITLIQRENAILGK 165
Query: 208 TLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL 267
E+ KE+E N ++ + K + KKE E ++ QL +K+ +++
Sbjct: 166 ---EKQACRKEMEMANKEKEATVIKFAMKEKLLIDAKKEKEAVEK---QLAEAKKEVKNV 219
Query: 268 EMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSML 327
+++ E+ ++ + +D K N+V ++ T + SKL+ N++++
Sbjct: 220 STRFLAVSEEKSRMTYI-IDEKC---NEVRKYQRECEKYKTEMGHLESKLKYHINKLNIE 275
Query: 328 NDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXX 387
+ A+ +L + E + N +L + ++ + FE
Sbjct: 276 TEAKAVVERKL-----EEEKNAPN--KLEEKANEKLKMEFEANTILLKHEITSKTEALDK 328
Query: 388 XTPGDQ-VNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYS-QX 445
T Q ++A+N ++L N+L+ + E ++ ++ + R++ N + SYS +
Sbjct: 329 LTKEQQKLSAAN---------KELQNQLQEITTEHNQLTEEYNRLRELHNSVEGSYSDEL 379
Query: 446 XXXXXXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQ--LRDNPL-LKEHYIR 502
T+N N E+K++D ++K+V+ L+ ++DN L++ ++
Sbjct: 380 LNSAKLRGQLEELQLLRTQNTIN--EEKLMD----QQKRVQKLEALVQDNETDLEQLKVK 433
Query: 503 KEKLALLEKENSDLLSGIETD-AIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKK 561
+++L + KE S+L+ ++ D + ++ + + KLL++E + + K +L++ + +
Sbjct: 434 RQELLTINKEMSELIVQLQNDICLAKAKAQGLDAENKLLKQEKLTYDTKYNQLEQQLSLE 493
Query: 562 SLE 564
+ E
Sbjct: 494 ASE 496
>7301391 [Z] KOG1850 Myosin-like coiled-coil protein
Length = 515
Score = 56.2 bits (134), Expect = 1e-07
Identities = 81/371 (21%), Positives = 163/371 (43%), Gaps = 53/371 (14%)
Query: 6 QIKEKPLESLD-ADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELE 64
+++E ++SLD +V L ++ + +E +S+L++E LQ + + E E
Sbjct: 20 KLEELVMKSLDECPSAEEKVKLLLQRH--VDSEKNVSRLTAELRV--LQRQMESQQREKE 75
Query: 65 NALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAH 124
+D +++ ++++L+ + +E ++II +++ + + ++ ++E+R E
Sbjct: 76 QVQRDLN----KSVLMRDKLQE---VCREQQRIIKSVKNESLL---QIKVEEERRKESQT 125
Query: 125 KLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRS 184
K S N+V ++ + N+ ++R E+ +K L++E
Sbjct: 126 KFQSSLNDVQKSL------------------AKNNEENIKLRDYNIEMTKKLKLLAE--Q 165
Query: 185 VQTSASHRNNSTEELQDLAVLN--KTLKEQLNYAKELEDMNLKQATELKKLRQNN----- 237
QT H E++Q A L+ K K Q+ A E E ++ + L+KL Q
Sbjct: 166 YQTREQHLEKLNEQVQLEAQLHQAKLQKCQVEAAMEKEILSKENQIGLEKLMQAQRAIKD 225
Query: 238 --DVQSLLKKENELLQSKLDQLN-SLQKKFE-----SLEMENISLQEKITQWGIVRLDGK 289
D + LK++ + +K D SLQK E +E+E +S K + + K
Sbjct: 226 LTDREHQLKEQLNIYTAKYDDFQQSLQKSNEVFGSYKVELEKMSKHTKKIEKEALGWRQK 285
Query: 290 FKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSI 349
++ N ++ +L E + + +LQ Q+ L + +ER L +D+E I
Sbjct: 286 YEKANAMVIDL---ATEKSLQTQHSERLQKQIQQLQKLLRALQLERTTLHKCLRDHEIEI 342
Query: 350 LNLKRLNHELE 360
L +L E E
Sbjct: 343 PALPQLPPEPE 353
>7297163 [R] KOG0249 LAR-interacting protein and related proteins
Length = 1205
Score = 56.2 bits (134), Expect = 1e-07
Identities = 85/429 (19%), Positives = 189/429 (43%), Gaps = 57/429 (13%)
Query: 20 LRRRVLTLQYKYTTLQNEY-----EISKLSSE-RETYSLQNKYDKSMNELE----NALKD 69
L ++ L+ + +Q E+ + +KL + RE + + ++ + LE NA ++
Sbjct: 283 LNNKISELEENMSRVQKEHCKAQDQCAKLQRDLRENVAQKEDQEERITTLEKRYLNAQRE 342
Query: 70 TKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSK 129
+ L++ N KL++EL+ K+A K E+ ++ +++ ++ L EQ++ + A KL
Sbjct: 343 STSLHDLNEKLEQELRHKEAQLKLHEE-------KIGAIEEKLELSEQKLAQHA-KLQPD 394
Query: 130 QNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSA 189
E +K +E + ++ + + + IR L+ L EK N + V+ +
Sbjct: 395 ME------EQLKARMEALTKVGNKAQERHGSAEDRIRGLETNLDEKTNEV-----VRLNQ 443
Query: 190 SHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENEL 249
+ N L+ L+ T+ + L+ + E ++LK+ + L + N + L+K ++
Sbjct: 444 RLKMNEEHNLR----LSSTVDKLLSESNERLQVHLKE--RMHALDEKNALTQELEKARKV 497
Query: 250 LQSKLDQLNSLQKKFES--LEMENIS---LQEKITQWGIVRLDG--KFKNPNDVITELNM 302
+ + + + K+ LE+EN LQ++I + I + + + +P+ V+
Sbjct: 498 AEELHHEKSEIMKELSKTRLEIENFKRQLLQQEIA-YNIQQTEALTRSLSPSSVVDPSGA 556
Query: 303 LQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQ- 361
R N+ L+ Q L++E A+ R+ +++E L++ H +Q
Sbjct: 557 FSRSNSHASFETHSLRRQSKQ--RLSEENALVRSM---AEQEWE----KLQQAAHAQQQA 607
Query: 362 QKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEEL 421
+L S +C +P +A + + Q + + NE++ + EE
Sbjct: 608 YELASAADC----DDSDVLYAAATDMMSPSGHTDAQTLAMMLQEQLDAINNEIRLIQEEK 663
Query: 422 SKTDDKIQK 430
T+ + ++
Sbjct: 664 QSTEARAEE 672
>7292701_2 [S] KOG4415 Uncharacterized conserved protein
Length = 1643
Score = 55.8 bits (133), Expect = 2e-07
Identities = 77/335 (22%), Positives = 142/335 (41%), Gaps = 15/335 (4%)
Query: 39 EISKLSSER-ETYSLQNKYDKSMNELENAL---KDTKILYEENIKLKEELKSKDALPKE- 93
EI L E +T S NK + + + K+ + E+ +KLKE+ + KE
Sbjct: 688 EIEGLDEEPPKTMSKDNKKKQKPGDAVATMTIDKEKEKAKEKELKLKEKEREAKLQEKEK 747
Query: 94 DEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQ 153
+EK+ R + + ++ E LKE++I E + K+ ++ KL+ E +
Sbjct: 748 EEKLKLKEREESLRMEREEKLKEEKIKEKEREEKLKEEKIKEKQREEKLKEEKLKEKERE 807
Query: 154 HETQINKHVEEIRYLQQELKEKENLISEL-RSVQTSASHRNNSTEELQDLAVLNKTLKEQ 212
+ + E+ + Q+E K +E I E R + R +E + L K +E+
Sbjct: 808 ERMKEKEREEKAKEKQREEKLREEKIKEKEREEKLKEKLREEKIKEKEKEEKLRKEREEK 867
Query: 213 LNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENI 272
+ KE E+ +K+ ++K+++ + L K++ E L+ K + L +K E E E
Sbjct: 868 MR-EKEREE-KIKEKERVEKIKEKEREEKLKKEKEEKLKEKEELLKKKEK--EEKEREE- 922
Query: 273 SLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSML--NDE 330
L+EK Q + + + K + +RE ++ D + L +E
Sbjct: 923 KLKEKERQEKLKEKEREEKLKRETEERQREKEREEKLKEKERAEKLKDLEKEVKLKEKEE 982
Query: 331 MAIERNQLLDLNKDYETSILNLKRLNHELEQQKLL 365
E+ + L L + E +K LE +KLL
Sbjct: 983 QLKEKEKELKLKEKKEKD--KVKEKEKSLESEKLL 1015
Score = 55.1 bits (131), Expect = 3e-07
Identities = 70/276 (25%), Positives = 126/276 (45%), Gaps = 28/276 (10%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
+IKEK E ++L+ + + + L+ E K ER + + K + E
Sbjct: 772 KIKEKERE----EKLKEEKIKEKQREEKLKEEKLKEKEREERMKEKEREEKAKE-KQREE 826
Query: 66 ALKDTKILYEENI-KLKEELKSKDALPKEDEKIITTLRTQVVSLKN-EVNLKEQRIVELA 123
L++ KI +E KLKE+L+ + KE E+ + R + + K E +KE+ VE
Sbjct: 827 KLREEKIKEKEREEKLKEKLREEKIKEKEKEEKLRKEREEKMREKEREEKIKEKERVE-- 884
Query: 124 HKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELR 183
K+ K+ E E +K E E L + E + K +E + +++LKEKE E
Sbjct: 885 -KIKEKERE-----EKLKKEKEEK---LKEKEELLKKKEKEEKEREEKLKEKER--QEKL 933
Query: 184 SVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLL 243
+ TEE Q + LKE+ A++L+D+ K+++ + L
Sbjct: 934 KEKEREEKLKRETEERQREKEREEKLKEK-ERAEKLKDLE-------KEVKLKEKEEQLK 985
Query: 244 KKENELLQSKLDQLNSLQKKFESLEMENISLQEKIT 279
+KE EL + + + +++K +SLE E + + ++
Sbjct: 986 EKEKELKLKEKKEKDKVKEKEKSLESEKLLISATVS 1021
>Hs4759006 [U] KOG0993 Rab5 GTPase effector Rabaptin-5
Length = 862
Score = 55.5 bits (132), Expect = 3e-07
Identities = 67/319 (21%), Positives = 136/319 (42%), Gaps = 28/319 (8%)
Query: 19 QLRRRVLTLQYKYTTLQNEYEIS---KLSSERETYSLQNKY-DKSMNELENALKDTKILY 74
Q R V +LQ +YE +L ER ++ +Y ++ + +L L + +
Sbjct: 109 QWREEVASLQAVMKETVRDYEHQFHLRLEQERTQWAQYREYAEREIADLRRRLSEGQ--E 166
Query: 75 EENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVT 134
EEN L+ E+K ++ ++ + ++ +LK+++ E +I EL + N
Sbjct: 167 EEN--LENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYL 224
Query: 135 NAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNN 194
A +S + ++E +L+ ++ + + E++R +EL E +L+ + R H
Sbjct: 225 EAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLR---KELHEVCHLLEQERQQHNQLKHTWQ 281
Query: 195 STEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQS-- 252
+ Q L +++ L L+Q ELKK Q +D Q L K + ++
Sbjct: 282 KAND-QFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEDDEQQRLNKRKDHKKADV 340
Query: 253 ----KLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKF---------KNPNDVITE 299
K+ + +L ++ S ++ N T+ + LD K+ ND+ +
Sbjct: 341 EEEIKIPVVCALTQEESSAQLSNEEEHLDSTRGSVHSLDAGLLLPSGDPFSKSDNDMFKD 400
Query: 300 LNMLQRENTFLLDTNSKLQ 318
+ + ++T L T+ LQ
Sbjct: 401 -GLRRAQSTDSLGTSGSLQ 418
>At5g49880 [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 726
Score = 55.5 bits (132), Expect = 3e-07
Identities = 123/638 (19%), Positives = 252/638 (39%), Gaps = 77/638 (12%)
Query: 12 LESLDADQLRRRVLTLQYKYTTLQNEYEIS------KLSSERETYSLQNKYDKSMNELEN 65
L++L+A+ ++ L +E E++ K+ E+ + N ++ EL++
Sbjct: 88 LQTLNANFTEADAERKHFRDKFLYSEQELAAAKAREKMLQEQLLMEINNSQERYTKELQS 147
Query: 66 ALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHK 125
+ ++ + + L+++ +S A +E K++ TQ L V+ +++R+
Sbjct: 148 C-HELEVKLQNEMNLRKKAESSAATAEEKAKLLEDKLTQ---LSGSVDREKKRL------ 197
Query: 126 LSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSV 185
N++ + KL + G L + + + E L+ +L+ + + E
Sbjct: 198 ----NNDIAQLGKEAKLSVARIGADLERMQCRAQNAETESNLLRSQLEHLKLIFDECLQE 253
Query: 186 QTSASHRNNS-TEEL---QDLAVLNKTLKEQLN-YAKELEDMNLKQATELKKLRQNNDVQ 240
+T + +S T E D +VL K L+E+L Y E+ E +KL+ +
Sbjct: 254 KTEVDKKLSSFTSEAASSSDNSVLVKHLQEELKRYEAEVR--------EARKLKSRHLDA 305
Query: 241 SLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLD-GKFKNPNDVITE 299
LL QS+ ++ S KF L++ L+ +++ W + D P+D++
Sbjct: 306 ELLNVNLLEEQSRRERAESELSKFHDLQLSMEKLENELSSWKSLLNDIPGVSCPDDIVMR 365
Query: 300 LNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILN-----LKR 354
++LQ E ++ + K+ ++ L E +E QL N E ++ LK
Sbjct: 366 FSVLQNE---VVQSTMKIGEASTRIKQL--EETLEAIQLGRQNAVSEAALAKEKSEALKT 420
Query: 355 LNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNEL 414
+E L EE G A +I+G+++ N +
Sbjct: 421 DVKRIEVMLTLVTEEKEQLKAVVNELRKSNSEGSVSGAADGA--LIQGFESSLAKKENYI 478
Query: 415 KRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQKI 474
K L ++L++ D + R++ +L ++ ++ ++LE K+
Sbjct: 479 KDLEQDLNQLKD-VNNRQRTEIEL---LNEKLVDEARRNKSLERDSDRLRSEISLLESKL 534
Query: 475 --LDLTSLKEKKVRILQLRD---------NPLLKEHYIRKEKLALLEKENSDLLSGIETD 523
D ++ + +R++ L E KE+L +E+ S ++
Sbjct: 535 GHGDYSAANTRVLRMVNTLGVENEAKQTIEALQAELQKTKERLQAVEELKS------QSG 588
Query: 524 AIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSLLGFKLEFLAHG 583
+ V I + L+++ + K+ R K VF + F A L G+K+ H
Sbjct: 589 DAGKLVDSHITGKIAQLKEQNATLEKREERYKTVFADRISVFRRACCELFGYKIVMDEH- 647
Query: 584 KVKLVSCYQPNKYIIA--DLQSNTLKSDLDKVIPEWET 619
+PN + LQS +SD +K+ E+E+
Sbjct: 648 -------QRPNGIPVTRFTLQSIYAQSDDEKLEFEYES 678
>At1g04600 [Z] KOG0160 Myosin class V heavy chain
Length = 1730
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/298 (23%), Positives = 130/298 (42%), Gaps = 29/298 (9%)
Query: 4 TPQIKEKPLESLDAD------QLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYD 57
T + K K + L + QLR T + + LQ+ + +L E + L+ D
Sbjct: 939 TQETKSKEISDLQSVLTDIKLQLRDTQETKSKEISDLQSALQDMQLEIEELSKGLEMTND 998
Query: 58 ---------KSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSL 108
+S++ L+N + +++ YEE K+ EE + KD +P D+ I L T+ L
Sbjct: 999 LAAENEQLKESVSSLQNKIDESERKYEEISKISEE-RIKDEVPVIDQSAIIKLETENQKL 1057
Query: 109 KNEVNLKEQRIVELAHKLSSKQNEVTNAI-ESMKLEIEGSGNILHQHET------QINKH 161
K V+ E++I EL K +T + E + + E N+ ++E + K
Sbjct: 1058 KALVSSMEEKIDELDRKHDETSPNITEKLKEDVSFDYEIVSNLEAENERLKALVGSLEKK 1117
Query: 162 VEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELED 221
+ E + +E+ I + S+ AS N E ++ LA NK L + ++ ++ D
Sbjct: 1118 INESGNNSTDEQEEGKYILKEESLTEDASIDN---ERVKKLADENKDLNDLVSSLEKKID 1174
Query: 222 MNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLE-MENISLQEKI 278
K+ E +L + ++ L E L+ K + L++K +E E I Q+ +
Sbjct: 1175 ETEKKYEEASRLCEER-LKQALDAETGLIDLK-TSMQRLEEKVSDMETAEQIRRQQAL 1230
Score = 55.1 bits (131), Expect = 3e-07
Identities = 79/352 (22%), Positives = 144/352 (40%), Gaps = 64/352 (18%)
Query: 71 KILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQ 130
K+ E LK K AL +D K T L QV L + + L++Q +E+ S +
Sbjct: 867 KVARRELRNLKMAAKETGAL--QDAK--TKLENQVEELTSNLELEKQMRMEIEEAKSQEI 922
Query: 131 NEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYL---QQELKEKE--NLISELRSV 185
+ + + +KL++ + + + + + +I+ QE K KE +L S L+ +
Sbjct: 923 EALQSVLTDIKLQLRDTQETKSKEISDLQSVLTDIKLQLRDTQETKSKEISDLQSALQDM 982
Query: 186 QTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNN-------- 237
Q + E DLA N+ LKE ++ + D + ++ E+ K+ +
Sbjct: 983 QLEIEELSKGLEMTNDLAAENEQLKESVSSLQNKIDESERKYEEISKISEERIKDEVPVI 1042
Query: 238 DVQSLLKKENE------LLQSKLDQLNSLQKKFE----------------------SLEM 269
D +++K E E L+ S ++++ L +K + +LE
Sbjct: 1043 DQSAIIKLETENQKLKALVSSMEEKIDELDRKHDETSPNITEKLKEDVSFDYEIVSNLEA 1102
Query: 270 ENI-------SLQEKITQWGIVRLD----GKFKNPNDVITE--------LNMLQRENTFL 310
EN SL++KI + G D GK+ + +TE + L EN L
Sbjct: 1103 ENERLKALVGSLEKKINESGNNSTDEQEEGKYILKEESLTEDASIDNERVKKLADENKDL 1162
Query: 311 LDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQ 362
D S L+ ++ +E + + L D ET +++LK LE++
Sbjct: 1163 NDLVSSLEKKIDETEKKYEEASRLCEERLKQALDAETGLIDLKTSMQRLEEK 1214
>7294543 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 1087
Score = 55.5 bits (132), Expect = 3e-07
Identities = 77/369 (20%), Positives = 169/369 (44%), Gaps = 31/369 (8%)
Query: 1 MSLTPQIKEKPLESLDADQLRRRVLT-LQYKYTTLQNEYEISKLSSERETYSLQNKYDKS 59
++ P + +K +E + +L L+ YT +++E+ I L + + NK +K
Sbjct: 352 LNQNPILLQKAMEEEEKHKLSSEKFNKLKTLYTKIRDEH-IQLLREQSDCNKSLNK-EKQ 409
Query: 60 MNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRI 119
+N L +TK L E K+K ++ K+ +K I + ++ L+ N +++
Sbjct: 410 VNS--QLLLETKELTNEISKIKVNVEEKEKTNLILQKQIEEHKEKIAHLEAVKNEMKEKF 467
Query: 120 VELAHKLSSKQNEVTNAIESMKLEI----EGSGNI------LHQHETQINKHVEEIRYLQ 169
++ + ++ ++ + E+++L E +GN+ L E+QIN E+I +
Sbjct: 468 DDVVKQKEIQELDIISTSENLRLNCLKVEELNGNLNDTLEKLSNAESQINAKTEDIEKML 527
Query: 170 QELKEKENLI---SELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQ 226
+ + ++ L+ E +SV+ S SH +LQ++ + ++ N K L+ + +
Sbjct: 528 KAFEAEKALLLTQIEQQSVE-SKSHSEAQNAQLQEIMDNLEQKDKEFNEVK-LQLSSAES 585
Query: 227 ATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRL 286
LK L N++++ + E +L +K++QL K + E +N LQ +T + +
Sbjct: 586 QISLKALEIQNNLKA-FEAEKSVLLTKIEQLGIEHK--NNSEAQNAQLQ--LTLNNLEQN 640
Query: 287 DGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYE 346
+ + +++ N L++EN N LQ +++S+ ++ Q+ + Y+
Sbjct: 641 ESALQQTQEIV---NQLRQENASAGQRNEDLQ---SKLSLTEVKLTQATQQIDAVTSSYQ 694
Query: 347 TSILNLKRL 355
+L L
Sbjct: 695 ICSTDLSEL 703
>YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1679
Score = 55.1 bits (131), Expect = 3e-07
Identities = 125/654 (19%), Positives = 254/654 (38%), Gaps = 81/654 (12%)
Query: 12 LESLDAD-QLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDT 70
LE+++A + R +L + L E +K ++ T S++ +K + ELE L T
Sbjct: 569 LENINAKMETRINILLRERDSYKLLASTEENKANTNSVT-SMEAAREKKIRELEAELSST 627
Query: 71 KILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQ 130
K+ EN + + L+ + + K+ + T + K KE+ + E L ++
Sbjct: 628 KV---ENSAIIQNLRKELLIYKKSQCKKKTTLEDFENFKGLAKEKERMLEEAIDHLKAEL 684
Query: 131 NEVTNAIES-MKLEIEGSGNILHQHETQINKHVEEIRYLQQEL----------------- 172
+ + + S + +E E + L Q +I EI L++E
Sbjct: 685 EKQKSWVPSYIHVEKERASTELSQSRIKIKSLEYEISKLKKETASFIPTKESLTRDFEQC 744
Query: 173 -KEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELK 231
KEK+ L ++R ++ SH N + +KE N + L + E++
Sbjct: 745 CKEKKEL--QMRLKESEISHNENKMDFSSKEGQYKAKIKELENNLERLRSDLQSKIQEIE 802
Query: 232 KLRQNND-----VQSLLKKENELLQSKLDQLNSLQKKFESL--EMENISLQEKITQWGIV 284
+R D Q+ + ++S L +L++ + E L E+EN+ + + T++
Sbjct: 803 SIRSCKDSQLKWAQNTIDDTEMKMKSLLTELSNKETTIEKLSSEIENLDKELRKTKFQYK 862
Query: 285 RLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIE-RNQLLDLNK 343
LD T L++ L D NS++Q + ++ N+ IE +N+L +
Sbjct: 863 FLDQNSDASTLEPTLRKELEQIQVQLKDANSQIQA-YEEIISSNENALIELKNELAKTKE 921
Query: 344 DYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGY 403
+Y+ I ELE+++ + EE P + A + ++
Sbjct: 922 NYDAKI--------ELEKKEKWAREE----DLSRLRGELGEIRALQPKLKEGALHFVQ-- 967
Query: 404 KNQTEDLTNELKRLNEELSKTD--------------DKIQKRRKITNDLGISYSQXXXXX 449
Q+E L NE++R+ + + K + + Q K DL +
Sbjct: 968 --QSEKLRNEVERIQKMIEKIEKMSTIVQLCKKKEMSQYQSTMKENKDLSELVIRLEKDA 1025
Query: 450 XXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALL 509
S+ + ++L++ + ++EK +L N + + +R E L+
Sbjct: 1026 ADCQAELTKTKSSLYSAQDLLDKH--ERKWMEEKADYERELISN-IEQTESLRVENSVLI 1082
Query: 510 EKENSDLLSGIETDAIPR-SVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEA 568
EK + + + D + S++ ++H+ LE ++ + K+ L F++
Sbjct: 1083 EKVDDTAANNGDKDHLKLVSLFSNLRHERNSLETKLTTC------------KRELAFVKQ 1130
Query: 569 VNSLLGFKLEFLAHGKVKLVSCYQPNKYIIADLQSNTLKSDLDKVIPEWETLFQ 622
N L + L + YQ + II + + T + ++ E + Q
Sbjct: 1131 KNDSLEKTINDLQRTQTLSEKEYQCSAVIIDEFKDITKEVTQVNILKENNAILQ 1184
Score = 53.5 bits (127), Expect = 1e-06
Identities = 99/542 (18%), Positives = 210/542 (38%), Gaps = 61/542 (11%)
Query: 37 EYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKS-KDALPKEDE 95
E EIS ++ + S + +Y + ELEN L+ + + I+ E ++S KD+ K +
Sbjct: 757 ESEISHNENKMDFSSKEGQYKAKIKELENNLERLRSDLQSKIQEIESIRSCKDSQLKWAQ 816
Query: 96 KIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSG------- 148
I ++ SL E++ KE I +L+ ++ + E+ K + S
Sbjct: 817 NTIDDTEMKMKSLLTELSNKETTIEKLSSEIENLDKELRKTKFQYKFLDQNSDASTLEPT 876
Query: 149 --NILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEEL------- 199
L Q + Q+ +I+ ++ + EN + EL++ ++ EL
Sbjct: 877 LRKELEQIQVQLKDANSQIQAYEEIISSNENALIELKNELAKTKENYDAKIELEKKEKWA 936
Query: 200 --QDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQL 257
+DL+ L L E +L++ L + +KLR N+V+ + K ++ K+ +
Sbjct: 937 REEDLSRLRGELGEIRALQPKLKEGALHFVQQSEKLR--NEVERIQKMIEKI--EKMSTI 992
Query: 258 NSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKL 317
L KK E + ++ + K ++RL+ K+ D EL T +K
Sbjct: 993 VQLCKKKEMSQYQSTMKENKDLSELVIRLE---KDAADCQAEL------------TKTK- 1036
Query: 318 QIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXX 377
+ + D + + ++ DYE +++ +EQ + L E
Sbjct: 1037 ----SSLYSAQDLLDKHERKWMEEKADYERELIS------NIEQTESLRVENSVLIEKVD 1086
Query: 378 XXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITND 437
D + ++ +++ L +L EL+ K K ND
Sbjct: 1087 DTAANNGDK-----DHLKLVSLFSNLRHERNSLETKLTTCKRELAFVKQKNDSLEKTIND 1141
Query: 438 LGISYSQXXXXXXXXXXXXXXXXSATK--NHANILEQKILDLTSLKEKKVRILQLRDNPL 495
L + + TK NIL++ ++ +K ++ + ++ +
Sbjct: 1142 LQRTQTLSEKEYQCSAVIIDEFKDITKEVTQVNILKEN----NAILQKSLKNVTEKNREI 1197
Query: 496 LKEHYIRKEKLALLEKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLK 555
K+ R+E+++ L+++ + ++ VY+ K +++ S +K + K
Sbjct: 1198 YKQLNDRQEEISRLQRDLIQTKEQVSINSNKILVYESEMEQCKQRYQDL-SQQQKDAQKK 1256
Query: 556 EV 557
++
Sbjct: 1257 DI 1258
>YFL008w [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1225
Score = 55.1 bits (131), Expect = 3e-07
Identities = 62/314 (19%), Positives = 137/314 (42%), Gaps = 42/314 (13%)
Query: 18 DQLRRRVLTLQYKYTTLQNEYEISKLSS-ERETYSLQNKYDKSMNELENALKDTKILYEE 76
++L++ Q + Q E KLS+ E SL+ K + NE+++ + +E
Sbjct: 231 NELQKFQALWQLYHLEQQKEELTDKLSALNSEISSLKGKIN---NEMKSLQRSKSSFVKE 287
Query: 77 NIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQ-NEVTN 135
+ + ++ D + K+ EK+++ L R++++ + + K+ + +
Sbjct: 288 SAVISKQKSKLDYIFKDKEKLVSDL----------------RLIKVPQQAAGKRISHIEK 331
Query: 136 AIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNS 195
IES++ +++ + + ETQ+ ++E+K+ + + + N
Sbjct: 332 RIESLQKDLQRQKTYVERFETQLKVVTRSKEAFEEEIKQSARNYDKFKLNENDLKTYNCL 391
Query: 196 TEEL---------QDLAVLN---KTLKEQLNYAKELEDMNLKQATELKKL------RQNN 237
E+ + +AVLN + ++E+L + D++ ++ TE + Q N
Sbjct: 392 HEKYLTEGGSILEEKIAVLNNDKREIQEELERFNKRADISKRRITEELSITGEKLDTQLN 451
Query: 238 DVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVI 297
D++ L ++N L +L +L LQ ES + L K+ + +V++D N + +
Sbjct: 452 DLRVSLNEKNALHTERLHELKKLQSDIESANNQEYDLNFKLRE-TLVKIDDLSANQRETM 510
Query: 298 TELNMLQRENTFLL 311
E + REN +L
Sbjct: 511 KERKL--RENIAML 522
>Hs19924131 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1173
Score = 55.1 bits (131), Expect = 3e-07
Identities = 87/444 (19%), Positives = 176/444 (39%), Gaps = 37/444 (8%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
++KE +E Q + + ++ + T+ + ++L+S +E + Y+ ++ L+N
Sbjct: 63 KVKEYQMELKYLKQYKEKACEIRDQITSKE-----AQLTSSKE---IVKSYENELDPLKN 114
Query: 66 ALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSL---------------KN 110
LK+ + + +KL E+K+ D+ K+ EK + L ++ + +
Sbjct: 115 RLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQR 174
Query: 111 EVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQ 170
V KE+++V+ H+ K N+ + + K E+ L + +H+ L Q
Sbjct: 175 TVREKERKLVD-CHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQ 233
Query: 171 ELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATEL 230
L + L R + +N + KT + +N E E + KQ E+
Sbjct: 234 SLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEI 293
Query: 231 KKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISL----QEKITQWGIVRL 286
+ + + +++ ++E+L K ++L +++ + + LE + + QE I +
Sbjct: 294 RD--KKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSK 351
Query: 287 DGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYE 346
K N + E+ LQ E L T KL + Q+ + R Q+ L KD
Sbjct: 352 AEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQL----NHHTTTRTQMEMLTKDKA 407
Query: 347 TSILNLKRL--NHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYK 404
++++ H E LL + T + + +
Sbjct: 408 DKDEQIRKIKSRHSDELTSLLGYFP-NKKQLEDWLHSKSKEINQTRDRLAKLNKELASSE 466
Query: 405 NQTEDLTNELKRLNEELSKTDDKI 428
+ NELKR E+LS +DK+
Sbjct: 467 QNKNHINNELKRKEEQLSSYEDKL 490
>Hs19924129 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1312
Score = 55.1 bits (131), Expect = 3e-07
Identities = 87/444 (19%), Positives = 176/444 (39%), Gaps = 37/444 (8%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
++KE +E Q + + ++ + T+ + ++L+S +E + Y+ ++ L+N
Sbjct: 202 KVKEYQMELKYLKQYKEKACEIRDQITSKE-----AQLTSSKE---IVKSYENELDPLKN 253
Query: 66 ALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSL---------------KN 110
LK+ + + +KL E+K+ D+ K+ EK + L ++ + +
Sbjct: 254 RLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQR 313
Query: 111 EVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQ 170
V KE+++V+ H+ K N+ + + K E+ L + +H+ L Q
Sbjct: 314 TVREKERKLVD-CHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQ 372
Query: 171 ELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATEL 230
L + L R + +N + KT + +N E E + KQ E+
Sbjct: 373 SLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEI 432
Query: 231 KKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISL----QEKITQWGIVRL 286
+ + + +++ ++E+L K ++L +++ + + LE + + QE I +
Sbjct: 433 RD--KKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSK 490
Query: 287 DGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYE 346
K N + E+ LQ E L T KL + Q+ + R Q+ L KD
Sbjct: 491 AEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQL----NHHTTTRTQMEMLTKDKA 546
Query: 347 TSILNLKRL--NHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYK 404
++++ H E LL + T + + +
Sbjct: 547 DKDEQIRKIKSRHSDELTSLLGYFP-NKKQLEDWLHSKSKEINQTRDRLAKLNKELASSE 605
Query: 405 NQTEDLTNELKRLNEELSKTDDKI 428
+ NELKR E+LS +DK+
Sbjct: 606 QNKNHINNELKRKEEQLSSYEDKL 629
>At3g18480 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 689
Score = 55.1 bits (131), Expect = 3e-07
Identities = 74/281 (26%), Positives = 134/281 (47%), Gaps = 28/281 (9%)
Query: 10 KPLESLDADQLRRR---VLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENA 66
K E DQLR+ V T+Q + QN+ + S+ ET Q++ M+E+E A
Sbjct: 209 KDREQALQDQLRQAKDSVSTMQKLHELAQNQLFELRAQSDEETAGKQSEVSLLMDEVERA 268
Query: 67 LKDTKILYEENIKLKEELKS--KDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAH 124
L E L+ +L++ +D K+ + I + L+N + KE+ I EL
Sbjct: 269 QTRLLTLEREKGHLRSQLQTANEDTDNKKSDNIDSNSM-----LENSLTAKEKIISELNM 323
Query: 125 KLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKEN--LISEL 182
++ + + + N ES EI+ ++L++ +T I + +++EL+E+ + L+ +L
Sbjct: 324 EIHNVETALANERESHVAEIKKLNSLLNKKDTIIEE-------MKKELQERPSAKLVDDL 376
Query: 183 R-SVQTSASHRNNSTE-ELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLR-QNNDV 239
R V+ + NS E E D A T +E L D N K E+ +L+ Q ++
Sbjct: 377 RKKVKILQAVGYNSIEAEDWDAAT---TGEEMSKMESLLLDKNRKMEHEVTQLKVQLSEK 433
Query: 240 QSLLKK---ENELLQSKLDQLNSLQKKFESLEMENISLQEK 277
SLL+K + E L +K+++ L +K E ++ +E+
Sbjct: 434 ASLLEKAEAKGEELTAKVNEQQRLIQKLEDDILKGYGSKER 474
>At4g27180 [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 744
Score = 54.3 bits (129), Expect = 6e-07
Identities = 65/270 (24%), Positives = 123/270 (45%), Gaps = 23/270 (8%)
Query: 2 SLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEY--EISKLSSERETYSLQNKYDKS 59
S+ Q+ ++ E L A++ + + +LQ E++K E +T + + +
Sbjct: 128 SVQVQLAKEQTEKLAANESLGKEREARIAVESLQAAITEELAKTQGELQTANQRIQAVND 187
Query: 60 MNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRI 119
M +L + LY N KL+ +L K EK T + + +LK + + ++
Sbjct: 188 MYKLLQEYNSSLQLY--NSKLQGDLDEAHENIKRGEKERTGIVESIGNLKGQFKALQDQL 245
Query: 120 VELAHKLSS-----KQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKE 174
A K+S +++E+ N I S+K+EI+ Q + ++H+ EI LQ E +
Sbjct: 246 A--ASKVSQDDVMKQKDELVNEIVSLKVEIQ-------QVKDDRDRHITEIETLQAEATK 296
Query: 175 KENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMN--LKQATELKK 232
+ + + +++ S +N EELQD V ++ K Q+ E MN +Q + +
Sbjct: 297 QNDFKDTINELESKCSVQNKEIEELQDQLVASER-KLQVADLSTFEKMNEFEEQKESIME 355
Query: 233 LRQNNDVQSLLKKENELLQSKLDQLNSLQK 262
L+ + L E E L+ KL N++Q+
Sbjct: 356 LKGRLEEAELKLIEGEKLRKKLH--NTIQE 383
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 54.3 bits (129), Expect = 6e-07
Identities = 90/455 (19%), Positives = 174/455 (37%), Gaps = 88/455 (19%)
Query: 83 ELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKL 142
ELK +AL + + L Q L+ ++ L +R EL S + ++
Sbjct: 456 ELKRLEALLERERGRSEALEQQDAGLRQQIELITKREAELQRIASEYEKDLA-------- 507
Query: 143 EIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDL 202
L QH ++ ++ ++QE++ ++ +E V+T + N +DL
Sbjct: 508 --------LRQHNYKV-----AMQKVEQEIELRKK--TEALLVETQRNLENEQKTRARDL 552
Query: 203 AVLNK--TLKEQLNYAKELEDMNLKQATELKKLRQNN-DVQSLLKKENELLQSKLDQLNS 259
+ +K +L++QL E+E + +KL+++N ++ +K + E ++ +D +++
Sbjct: 553 NINDKVVSLEKQL---LEMEQSYKTETENTQKLKKHNAELDFTVKSQEEKVRDMVDMIDT 609
Query: 260 LQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQI 319
LQK E L EN LQ + Q E N+ + + +K+Q
Sbjct: 610 LQKHKEELGQENAELQALVVQ------------------EKNLRSQLKEMHKEAENKMQT 651
Query: 320 DFN--QMSMLNDEMAIERNQLL-----DLNKDYETSILNLKRLNHELEQQKLLSFEECXX 372
N + +M ++ A E N+ L DL K + LK +Q+
Sbjct: 652 LINDIERTMCREQKAQEDNRALLEKISDLEKAHAGLDFELKAAQGRYQQE---------- 701
Query: 373 XXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELS---KTDDKIQ 429
+ S ++ + +++ +LNEE S K D Q
Sbjct: 702 ---------------VKAHQETEKSRLVSREEANLQEVKALQSKLNEEKSARIKADQHSQ 746
Query: 430 KRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQK------ILDLTSLKEK 483
++ + + L + Y Q + L+Q+ +L SL
Sbjct: 747 EKERQLSMLSVDYRQIQLRLQKLEGECRQESEKVAALQSQLDQEHSKRNALLSELSLHSS 806
Query: 484 KVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLS 518
+V L+ R+N L KE ++E E++ + L S
Sbjct: 807 EVAHLRSRENQLQKELSTQREAKRRFEEDLTQLKS 841
>SPAC4A8.05c [Z] KOG0161 Myosin class II heavy chain
Length = 2104
Score = 53.9 bits (128), Expect = 7e-07
Identities = 91/431 (21%), Positives = 194/431 (44%), Gaps = 48/431 (11%)
Query: 40 ISKLSSERETYSLQNKYDKSMNELENALKDTK-------ILYEENIKLKEELKSKDALPK 92
+ L +T + D +N L+N L+ TK I E ++L +L+ + AL
Sbjct: 825 LKPLLGTTQTDEYLRRKDALINNLQNQLESTKEVANELTITKERVLQLTNDLQEEQALAH 884
Query: 93 EDEKII--TTLRTQVV-----SLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIE 145
E + ++ R +VV SL+N+V + +++ L + S + ++ N + EI
Sbjct: 885 EKDILVERANSRVEVVHERLSSLENQVTIADEKYEFLYAEKQSIEEDLAN----KQTEIS 940
Query: 146 GSGNILHQHETQINKHVEEIRYLQQELKEKE-NLISELRSVQTSASHRNNSTEELQDLAV 204
++ E +++ ++ + + + KE E + ++ + Q S+ H +N + + + +
Sbjct: 941 YLSDLSSTLEKKLSSIKKDEQTISSKYKELEKDYLNIMADYQHSSQHLSNLEKAINEKNL 1000
Query: 205 LNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKF 264
+ L E+L + +++ LKQ + K+++ + + LK + +S+L L S +
Sbjct: 1001 NIRELNEKL--MRLDDELLLKQRSYDTKVQELREENASLKDQCRTYESQLASLVSKYSET 1058
Query: 265 ES----LEMENISLQEKITQWGIVRLDGKFKNP------NDVITELNMLQRENTFLLDTN 314
ES E E + Q++IT++ +L F+NP NDV + L + ++
Sbjct: 1059 ESELNKKEAELVIFQKEITEYR-DQLHKAFQNPEKTHNINDV--KSGPLNSDENIYSTSS 1115
Query: 315 SKLQI--DFNQMSMLNDEMAIERNQ-LLDLNKDYETSIL---NLKRLNHEL-EQQKLLSF 367
+ L I D ++ L+ + A + ++ + ++++ E SI L+R N EL + + L +
Sbjct: 1116 TTLSILKDVQELKSLHTKEANQLSERIKEISEMLEQSIATEEKLRRKNSELCDIIEALKY 1175
Query: 368 EECXXXXXXXXXXXXXXXXXXTPGD-QVNASNIIE------GYKNQTEDLTNELKRLNEE 420
+ T G + NAS+ I+ Y+++ DL N+L++ +
Sbjct: 1176 QIQDQETEIISLNADNLDLKDTNGVLEKNASDFIDFQGIKSRYEHKISDLLNQLQKERCK 1235
Query: 421 LSKTDDKIQKR 431
+ K + R
Sbjct: 1236 VGLLKQKTENR 1246
>SPAC27D7.13c [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 670
Score = 53.9 bits (128), Expect = 7e-07
Identities = 88/393 (22%), Positives = 158/393 (39%), Gaps = 60/393 (15%)
Query: 4 TPQIKEKPL-ESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNE 62
TP K L E+L ++ + R+ L + T L+ + I KL+ E E Q + +S N
Sbjct: 196 TPHSKGSYLKENLKSELRKGRLDELMCENTALKEK--IDKLNKELEKVEPQLTFLRSKNS 253
Query: 63 LENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVEL 122
+E N + ++ LK A+ KE I LR + + ++ N K
Sbjct: 254 IEKP---------RNFRREKFLKKFLAMQKE----IKYLRKRKLQIRKIPNYKYSDRSLN 300
Query: 123 AHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKE------ 176
+ S+ N T S L + +L + Q++ E ++ + EK
Sbjct: 301 SKTPKSQDNWTTQVTPSSLLGVSEVSKVLQLKQVQVDI-TELVKIPKNPFSEKLTISNVN 359
Query: 177 ---NLISELRSVQTSASHRN----NST--EELQDLAVLNKTLKEQLNYAKELEDMNLKQA 227
N++ +Q S ++ N NST +EL +L N ++ + LE+ L
Sbjct: 360 RYLNIVPGSLDLQFSLTNENFVHWNSTVYQELLNLKSNNSSVDGVKTRRQLLEENALLSH 419
Query: 228 TELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKIT-------- 279
LK + D+++L + E+ + ++LN +Q++ + L IS Q +T
Sbjct: 420 KVLKLTEEIQDLETLNQLNTEIEARQSEKLNEVQEETQRLSQLLISSQPALTEVKHLKLC 479
Query: 280 ----QWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIER 335
Q +++L+ K + N VI ELN KL + S + D++
Sbjct: 480 LSDSQEELLQLNAKLEKANIVIDELN----------SAKLKLSKQVEEESSMKDDLTEMN 529
Query: 336 NQLLDLNKDYETSILNLKRLNHELEQQKLLSFE 368
+L + + YE + N E+ + L FE
Sbjct: 530 QRLKEQIESYENEV------NSEITSRTLKEFE 556
>At5g48600 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1241
Score = 53.9 bits (128), Expect = 7e-07
Identities = 72/276 (26%), Positives = 131/276 (47%), Gaps = 41/276 (14%)
Query: 25 LTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEEL 84
L Q K T + E ++K++ +R+ SLQN LEN+LKD ++ +E+ EEL
Sbjct: 258 LKWQEKATKMAYEDTVAKITEQRD--SLQN--------LENSLKDERVKMDES---NEEL 304
Query: 85 KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIV----ELAH------KLSSKQNEVT 134
K +++ ++ +K L ++ + K + E++ V +L H KL K + +
Sbjct: 305 KKFESVHEKHKKRQEVLDNELRACKEKFKEFERQDVKHREDLKHVKQKIKKLEDKLEKDS 364
Query: 135 NAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQ--TSASHR 192
+ I M E E S N+ I K E I LQ+ L ++E + E++++ + +R
Sbjct: 365 SKIGDMTKESEDSSNL-------IPKLQENIPKLQKVLLDEEKKLEEIKAIAKVETEGYR 417
Query: 193 NNSTEELQDLAVLNKTL---KEQLNYA-KELEDMNLKQATELKKL----RQNNDVQSLLK 244
+ T+ +L K L + +L+ A E E ++ K LK +Q +D+ + K
Sbjct: 418 SELTKIRAELEPWEKDLIVHRGKLDVASSESELLSKKHEAALKAFTDAQKQLSDISTRKK 477
Query: 245 KENELLQS-KLDQLNSLQKKFESLEMENISLQEKIT 279
++ S K D Q+ E+ ++E SL+E+ T
Sbjct: 478 EKAAATTSWKADIKKKKQEAIEARKVEEESLKEQET 513
>7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 1456
Score = 53.9 bits (128), Expect = 7e-07
Identities = 93/524 (17%), Positives = 194/524 (36%), Gaps = 61/524 (11%)
Query: 42 KLSSERETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTL 101
K +S +E + KYD++ NE+ + +L+ E + + + + L
Sbjct: 600 KDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKL 659
Query: 102 RTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKH 161
+ + R+ E + + + + ++ + E+E S + + +T I +
Sbjct: 660 QDE-----------STRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRA 708
Query: 162 VEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELED 221
E + Q EL+ + + QT AS + +E E +YA ELE
Sbjct: 709 QGEKEHFQSELERVTYELERAHAAQTKASASVEAAKE------------EAAHYAVELEK 756
Query: 222 MN---LKQATELKKLRQNNDV---QSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQ 275
M K EL+KL+ + LK+ENE L+ KLD+ +E+E I +
Sbjct: 757 MRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDK--------TLMELETIRGK 808
Query: 276 EKITQWGIVRLDGKFKNPNDVITELNM-LQRENTFLLDTNSKLQIDFNQMSMLNDEMAIE 334
+ F+ D ++ M +Q + L +T+ +L++ +++ + +
Sbjct: 809 SQYE-------SESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQ 861
Query: 335 RNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQV 394
R++L + + E + ++L E+++ +L E ++
Sbjct: 862 RSELERAHIEREKARDKHEKLLKEVDRLRLQQSSEIDRLRDRLEKALQSRDATELEAGRL 921
Query: 395 -----NASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXX 449
A + + TE E +R+ EL + D+++K + +
Sbjct: 922 AKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAE--------AEREALRQA 973
Query: 450 XXXXXXXXXXXSATKNHANILEQKILDLTSLKEKKVRILQLRDNPLL---KEHYIRKEKL 506
+ H LE + L +E+ V L+ L+ KE + +L
Sbjct: 974 NRSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAEL 1033
Query: 507 ALLEKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKK 550
+EN L +G + + + + ++KEI + +K
Sbjct: 1034 QKTREENRKLRNGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQK 1077
Score = 51.2 bits (121), Expect = 5e-06
Identities = 91/469 (19%), Positives = 172/469 (36%), Gaps = 65/469 (13%)
Query: 16 DADQLRRRVLTLQYKYTTLQNEYEISKLSSER---ETYSLQNKYDKSMNELENALKDTKI 72
DA++ R LQ K Q E K E E SL+ + +K+ + + D
Sbjct: 340 DAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDR 399
Query: 73 LYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVN----------LKEQRIV-- 120
+ E K+KEE++ A + + L+ + +NEV+ + +R+V
Sbjct: 400 AFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLE 459
Query: 121 --ELAHKLSSKQNEVTNAI----------ESMKLEIEGSGNILHQHETQINKHVEEIRYL 168
+L + + Q+++ A+ E++ L+ + L + + Q+ + +E
Sbjct: 460 KEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQF 519
Query: 169 QQELKEKENLISELRSVQTSASHRNNSTEELQ-DLAVLNKTLKEQLNYAKELEDMNLKQA 227
EL E L S QT E +Q DL VL + ++ ++L+
Sbjct: 520 SDEL---ETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAV 576
Query: 228 TELKKLRQNND-----VQSLL------KKENELLQSKLD----QLNSLQKKFESLEMENI 272
TE++ L++ D Q L+ KE E + K D ++ LQ + ++ E +
Sbjct: 577 TEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRA 636
Query: 273 SLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMA 332
L+ + + G+ + +L LQ E+T L + + + ++ D
Sbjct: 637 RLEVEAERSGLAASKAR--------EDLRKLQDESTRLQEACDRAALQLSRAKECEDNAR 688
Query: 333 IERNQLLDLNKDYETSI-----------LNLKRLNHELEQQKLLSFEECXXXXXXXXXXX 381
E D +T I L+R+ +ELE+ +
Sbjct: 689 SELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAA 748
Query: 382 XXXXXXXTPGDQVNASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQK 430
D+ S + T+ E +RL EE + +K+ K
Sbjct: 749 HYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDK 797
>Hs4758648 [Z] KOG0240 Kinesin (SMY1 subfamily)
Length = 963
Score = 53.1 bits (126), Expect = 1e-06
Identities = 86/449 (19%), Positives = 180/449 (39%), Gaps = 44/449 (9%)
Query: 7 IKEKPLESLDADQL----RRRVLTLQYKYTTLQNEYEISKLSSERETYSLQN---KYDKS 59
+++ + LD ++L RR +Q + LQ E + SK + +L+ YD+
Sbjct: 446 VEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQK 505
Query: 60 MNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRI 119
E+E+ K+ ++ L +EL K A + ++ ++ LK N +++R
Sbjct: 506 SQEVEDKTKEYEL-------LSDELNQKSA-------TLASIDAELQKLKEMTNHQKKRA 551
Query: 120 VELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLI 179
E+ L E+ A+ + ++ ++ + T ++ + ++ E+K
Sbjct: 552 AEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISK---MKSEVKTMVKRC 608
Query: 180 SELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDV 239
+L S QT ++ + E ++LA + + K L + Q E KK + V
Sbjct: 609 KQLESTQTESNKKMEENE--KELAACQLRISQHEAKIKSLTE--YLQNVEQKKRQLEESV 664
Query: 240 QSL------LKKENELLQSKLDQLNSLQKKFESLEM--ENISLQEKITQWGIVRLDGKFK 291
+L L+ + ++ + + + LN +Q E + + I + Q I L + +
Sbjct: 665 DALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVE 724
Query: 292 NPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILN 351
+IT+ LQ +N ++ +L+++ ++ + E + + ++L + E + +
Sbjct: 725 AKAKLITD---LQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQD 781
Query: 352 LKRLNHEL--EQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTED 409
LK L + E Q L + + G I +N E
Sbjct: 782 LKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQ 841
Query: 410 LT---NELKRLNEELSKTDDKIQKRRKIT 435
LT +L R N +L K++KR + T
Sbjct: 842 LTKVHKQLVRDNADLRCELPKLEKRLRAT 870
>YKL179c [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 679
Score = 52.8 bits (125), Expect = 2e-06
Identities = 75/323 (23%), Positives = 147/323 (45%), Gaps = 31/323 (9%)
Query: 58 KSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLK-- 115
K + E + L+D Y + LK L + + T +TQ ++ E +
Sbjct: 121 KELKEKISYLEDKLAKYADYETLKSRLLDLEQSSAKTLAKRLTAKTQEINSTWEEKGRNW 180
Query: 116 EQRIVELAHKLSS--KQNEVTNAIESMKLEIEGSGNI---LHQHETQINKHVEEIRYLQQ 170
++R +L +L++ +QN+ A S ++IEG+GN ++ +++ + E + Q
Sbjct: 181 KEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNEDGDQENNQKEVSTRIAEYNLVTQ 240
Query: 171 ELKEKENLISEL--RSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQAT 228
EL+ + I +L R+ + S + ++E ++ + K LK LN E E+ L +
Sbjct: 241 ELETTQARIYQLEKRNEELSGALAKATSEAEKETELHAKELK--LNQL-ESENALLSASY 297
Query: 229 ELKKLRQNNDVQSLLKKENELL---QSKLDQLNSLQKKFESLE-----MENISLQEKITQ 280
E ++ ++ + L ++ N ++ +S +L ++++K + E +S +KI +
Sbjct: 298 EQERKSTSHAINELKEQLNSVVAESESYKSELETVRRKLNNYSDYNKIKEELSALKKI-E 356
Query: 281 WGIVRLDGKFKNPNDVITELNMLQRENTF---LLDTNSKLQIDFNQMSMLNDEMAIERNQ 337
+G+ D + ND+ +E + +NTF LL N KLQ + + ERN+
Sbjct: 357 FGVNEDD----SDNDIRSED---KNDNTFESSLLSANKKLQATLAEYRSKSTAQEEERNE 409
Query: 338 LLDLNKDYETSILNLKRLNHELE 360
L + I LK N +LE
Sbjct: 410 LKKSVDQLKQQIATLKEANEKLE 432
>Hs5453591 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1197
Score = 52.8 bits (125), Expect = 2e-06
Identities = 73/347 (21%), Positives = 149/347 (42%), Gaps = 36/347 (10%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSE-RETYSLQNKYDKSMNEL- 63
+IKE L +L+ ++L T + KY L+ ++E+ ++ +T Q+ Y K EL
Sbjct: 689 RIKENELRALE-EELAGLKNTAE-KYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELD 746
Query: 64 ---------ENALKDTKIL-------YE--ENIKLKEELKSKDALPKEDEKIITTLRTQV 105
E LK+TK + YE EN K+K ++ K+ +K + +T+
Sbjct: 747 ALKKTIEESEETLKNTKEIQRKAEEKYEVLEN-KMKNAEAERERELKDAQKKLDCAKTKA 805
Query: 106 VSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQIN------ 159
+ ++ K+Q + + +L + E T S K ++E + +E+QI
Sbjct: 806 DASSKKMKEKQQEVEAITLELEELKREHT----SYKQQLEAVNEAIKSYESQIEVMAAEV 861
Query: 160 -KHVEEIRYLQQEL-KEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLN-YA 216
K+ E + Q+E+ K+KE + ++ ++ + N+ + L++ K L ++ +
Sbjct: 862 AKNKESVNKAQEEVTKQKEVITAQDTVIKLNMQKWQNTRSKTMILSLKIKELDHHISKHK 921
Query: 217 KELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQE 276
+E ED K + LK N + L + N K + ++ + L+ L
Sbjct: 922 REAEDGAAKVSKMLKDYDWINAERHLFGQPNSAYDFKTNNPKEAGQRLQKLQEMKEKLGR 981
Query: 277 KITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQ 323
+ + L + ND++ + +++ + + +L T L NQ
Sbjct: 982 NVNMRAMNVLTEAEERCNDLMKKKRIVENDKSKILTTIEDLDQKKNQ 1028
>At3g44050 [Z] KOG4280 Kinesin-like protein
Length = 1229
Score = 52.8 bits (125), Expect = 2e-06
Identities = 85/391 (21%), Positives = 167/391 (41%), Gaps = 57/391 (14%)
Query: 16 DADQLRRRVLTLQYKYTTLQN---EYEISKLSSERETYSLQN---KYDKSMNELENALKD 69
+ D+L+R + + K N E E+ +SSE+ T L + K + + +L + K
Sbjct: 839 EKDELKRLLSSPDQKKPIEANSDTEMELCNISSEKSTEDLNSAKLKLELAQEKLSISAKT 898
Query: 70 TKIL--YEENI----KLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELA 123
+ EENI KL +E K + KE + + +++T + E+++ L
Sbjct: 899 IGVFSSLEENILDIIKLSKESKETEEKVKEHQSELGSIKTVSDQTNARKEVAEKKLAALR 958
Query: 124 HKLSS---------------------------KQNEVTNAIESMKLEIEGSGNILHQHET 156
LS+ ++NE + I S K EI+ + + Q E
Sbjct: 959 CSLSNFASSAVYFQQREERARAHVNSFSGYLNQKNEELDVIRSHKREIDAAMGKIQQSEA 1018
Query: 157 QINKHVEEIRY-LQQELK--EKENLISELRSVQTS--ASHRNNSTEELQDLAVLNKTLKE 211
++ ++ ++ + +E K E+E ++ + ++ + A+ S EE L K +E
Sbjct: 1019 ELKSNIVMLKIKVDEENKRHEEEGVLCTIDNILRTGKATDLLKSQEEKTKLQSEMKLSRE 1078
Query: 212 QL-NYAKELEDM---NLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL 267
+L + KE++DM +LK E+K + + S + E+E ++ N++Q+K
Sbjct: 1079 KLASVRKEVDDMTKKSLKLEKEIKTMETEIEKSSKTRTESE-----MELENTIQEKQTIQ 1133
Query: 268 EMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSML 327
EME + E Q I+ + + +D+ E M+ RE + +K + N + +
Sbjct: 1134 EMEEQGMSE--IQNMIIEIH-QLVFESDLRKEEAMIIREELIAEELRAK-DVHTNMIERV 1189
Query: 328 NDEMAIERNQLLDLNKDYETSILNLKRLNHE 358
+ + NQ ++ E + N+ L HE
Sbjct: 1190 ENALKTLENQNNSVSGKIEEEVENVLSLVHE 1220
>7303314 [S] KOG0992 Uncharacterized conserved protein
Length = 611
Score = 52.8 bits (125), Expect = 2e-06
Identities = 70/333 (21%), Positives = 148/333 (44%), Gaps = 46/333 (13%)
Query: 58 KSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQ 117
+ + E + + T + E++++ + KD +E EKI + ++ LKN ++ +EQ
Sbjct: 84 QQLQEEKTRVDKTNEILLESVRVAQT--QKDIYCEEQEKIQNLQQIEIDKLKNLLSFREQ 141
Query: 118 RIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKEN 177
V+ + T IES+ E+E I E + +E++R+ Q+ EK
Sbjct: 142 ESVD----RMGLMRQQTQQIESLSEELERLRPIESVAE-DLRDELEQLRHSTQQ--EKNL 194
Query: 178 LISELRSVQTSASH-----------------RNNSTEELQDLAVLNKTLKEQLNYAK-EL 219
L + L +VQ H + NS +++Q L +K L++ L A +L
Sbjct: 195 LTTTLAAVQEENRHLKKRMKIVEESRLESLGKLNSEQQVQALIREHKLLEQHLEEAHLQL 254
Query: 220 EDM-------NLKQATELKKL-----RQNNDVQSLLKKENELLQSKLDQLNSLQKKFESL 267
D+ NL T++ +L + + + LK ++ ++S+ L+K + +
Sbjct: 255 SDIKGSWSGQNLALETQVSRLSKQVAEETTEKRKALKSRDDAIESRKQVSFELEKAKDEI 314
Query: 268 EMENIS---LQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQI---DF 321
+ + L+E+I + + + + +N V+ E N Q T + D ++L F
Sbjct: 315 KQRDDKVKLLEEEIDELSVALKECREENEQQVLFERNKSQNLETEVKDLKTRLTAADDRF 374
Query: 322 NQMSMLNDEMAIE-RNQLLDLNKDYETSILNLK 353
++ S +++A + R Q+ + + + +I+ L+
Sbjct: 375 SEYSSNAEQVAQKLRVQVTEKQEQLDETIMQLE 407
>YIL144w [D] KOG0995 Centromere-associated protein HEC1
Length = 691
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/360 (20%), Positives = 158/360 (43%), Gaps = 32/360 (8%)
Query: 35 QNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKIL--YEENIKLKEELK-SKDALP 91
QN EI+ LS +T Q++ + + L Y+ +KL++ + S L
Sbjct: 246 QNTQEITILSQPLKTLDEQDQRQERYELMVEKLLIDYFTESYKSFLKLEDNYEPSMQELK 305
Query: 92 KEDEKIITTLRTQVVSLKNEV-NLKE--QRIVELAHK----------LSSKQNEVTNAIE 138
EK + + T + +L+ + NL E Q +++++ K L S N+ N +
Sbjct: 306 LGFEKFVHIINTDIANLQTQNDNLYEKYQEVMKISQKIKTTREKWKALKSDSNKYENYVN 365
Query: 139 SMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISE----LRSVQTSASHRNN 194
+MK + + L + +++ EEI+ LQ + E ++ + + R
Sbjct: 366 AMKQKSQEWPGKLEKMKSECELKEEEIKALQSNISELHKILRKKGISTEQFELQNQEREK 425
Query: 195 STEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQ-NNDVQSLLKKENELLQSK 253
T EL + + + L + +++LE + ++ L LRQ ++ +Q+L + ++L +
Sbjct: 426 LTRELDKINIQSDKLTSSIK-SRKLEAEGIFKSL-LDTLRQYDSSIQNLTRSRSQLGHNV 483
Query: 254 LD---QLNSLQKKFESLEMENISLQEKITQWGIVR--LDGKFKNPNDVITE-LNMLQREN 307
D ++N + + E IS ++ + + + ND I E + ++++N
Sbjct: 484 NDSSLKINISENLLDRDFHEGISYEQLFPKGSGINESIKKSILKLNDEIQERIKTIEKDN 543
Query: 308 TFLLDTNSKLQIDFNQMSMLNDEMAI---ERNQLLDLNKDYETSILNLKRLNHELEQQKL 364
L L+ D N+ + +N+++ + E N +L+K +L +R+ E ++K+
Sbjct: 544 ITLEKDIKNLKHDINEKTQINEKLELELSEANSKFELSKQENERLLVAQRIEIEKMEKKI 603
>SPAC688.11 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 1092
Score = 52.4 bits (124), Expect = 2e-06
Identities = 57/286 (19%), Positives = 129/286 (44%), Gaps = 23/286 (8%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYS-LQNKYDKSMNELE 64
Q+ + + + +QL ++ +Q + + E ++ + E + L N+YD + LE
Sbjct: 387 QMAQAEQQRIAQEQLAQQQFQMQTQGQLAELEQQLLATRGQLEQSNVLLNQYDARVRTLE 446
Query: 65 NALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAH 124
N L + + L+E++ D L I +L+ Q+++ KN K + + +L
Sbjct: 447 NELS------QAGVNLQEQIHQNDDL-------IESLKNQILTWKN----KYEALAKLYT 489
Query: 125 KLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRS 184
+L + ++ + + ++L+ + + + E + + L + E++ EL +
Sbjct: 490 QLRQEHLDLLSKYKQIQLKASSAQEAIDKKEKMEREMKNKNLELADMILERDRARHELET 549
Query: 185 VQTSASHRNNSTEELQDLAVL-NKTLKEQLNYAKELEDMNLKQATELKKLRQ--NNDVQS 241
+ S + STE ++L +L K + N + E+ ++ + TE+ L ++ +
Sbjct: 550 MHRSQRDKQESTE--RELRLLQEKAASLERNKSSEVSNLLSRYNTEVAHLEDALHSKDRE 607
Query: 242 LLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLD 287
L EL ++ LQ+K E LE++ ++ E + Q ++LD
Sbjct: 608 LANLGVELKSTENRYRQLLQEKEEELEIQKAAVDESLLQLSKLQLD 653
>Hs18560881 [Z] KOG0244 Kinesin-like protein
Length = 1234
Score = 52.4 bits (124), Expect = 2e-06
Identities = 69/304 (22%), Positives = 129/304 (41%), Gaps = 34/304 (11%)
Query: 3 LTPQIKEKPLESLDADQLRRRV---LTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKS 59
LT Q+ EK L+ +LR+ V L LQ TL+++ + L +
Sbjct: 422 LTEQVNEKLNAKLE--ELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDE 479
Query: 60 MNELENALKDTKILYEENIKLKEEL-KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQR 118
A DT + E ++ E +S DA + + +VV L N + LKE
Sbjct: 480 TVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEA- 538
Query: 119 IVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENL 178
L K++ N++ I Q++ I E+ LQ KEKE L
Sbjct: 539 ---LVRKMTQNDNQLQP--------------IQFQYQDNIKNLELEVINLQ---KEKEEL 578
Query: 179 ISELRSVQTSASHRNNSTEE---LQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQ 235
+ EL++ + + + S LQ+L LK++LN +L + LK++TE +
Sbjct: 579 VRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKL--LKLKESTERTVSKL 636
Query: 236 NNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQE--KITQWGIVRLDGKFKNP 293
N ++ + + +L++ + ++ + + E I L+E + Q+ +++L+ F+
Sbjct: 637 NQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQ 696
Query: 294 NDVI 297
+ V+
Sbjct: 697 SSVL 700
>CE20131 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase Citron
Length = 1256
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/367 (19%), Positives = 158/367 (42%), Gaps = 45/367 (12%)
Query: 16 DADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYE 75
D++Q + + K T + + L + R K ++ + + AL+D + + E
Sbjct: 313 DSEQATKYLHAENMKLTRQKADIRCDLLEARRNLKGFDEKREELEKQRDEALEDVRRITE 372
Query: 76 ENIKLKEELKSKDALPKEDEKIITTLRTQVV----------SLKNEVNLKEQRIVELAHK 125
++ EL+S L +E E+ I L+++V ++KNE+ E+++ ++
Sbjct: 373 LKKNVEIELRSLKLLAEEREEQIDELKSRVAGYEVLRRDHEAVKNELAKAEEKLNKMGAH 432
Query: 126 LSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSV 185
L + ++ +++K EGS + Q N+ V IR L+ L+ + + EL V
Sbjct: 433 LVMADKQ-SSHFKTLKETAEGS---RRRAIEQCNEMVARIRGLEASLENQRKVEQELEMV 488
Query: 186 QTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSL--- 242
+ + E +++ + + L+Y +EL + + +++++++S
Sbjct: 489 KAENVRQAKKIEFMKE-----EIQETHLDYREELSKLAKGGGSHEADSQRDSELRSAKKT 543
Query: 243 ---LKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITE 299
+K +N+ LQ L+++ Q K LE EN+ L+ K + I +
Sbjct: 544 IQEVKADNKKLQQILEEVRQNQSKV--LE-ENVKLR---------------KGMAEAIEK 585
Query: 300 LNMLQRENTFLLDTNSKLQIDF--NQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNH 357
+ +R + +LQ++ N+ +L E ++ +L L K+ + L +
Sbjct: 586 IEEFKRNWHSSREAGERLQLEAKENEEKVLKVEEELQEKRLEVLEKEELVNYLQSQINTK 645
Query: 358 ELEQQKL 364
+ +Q KL
Sbjct: 646 QTKQPKL 652
>At5g54670 [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 746
Score = 52.4 bits (124), Expect = 2e-06
Identities = 53/224 (23%), Positives = 106/224 (46%), Gaps = 22/224 (9%)
Query: 39 EISKLSSERETYSLQNKYDKSMNELENALKD-TKILYEENIKLKEELKSKDALPKEDEKI 97
E+ K + +T N+ +S+N++ L++ L N KL+ +L K EK
Sbjct: 176 ELGKAQGDLQT---ANQRIQSVNDMYKLLQEYNSSLQLYNSKLQGDLDEAHETIKRGEKE 232
Query: 98 ITTLRTQVVSLKNEVN-LKEQRIVELAHK--LSSKQNEVTNAIESMKLEIEGSGNILHQH 154
T + + +LK + + L+EQ A + + ++ E+ N I S+K+E++ Q
Sbjct: 233 RTAIIENIGNLKGQFSALQEQLAASKASQEDIMKQKGELVNEIASLKVELQ-------QV 285
Query: 155 ETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLN 214
+ ++H+ E++ LQ E + + + ++T+ S ++ +LQD V + + E++N
Sbjct: 286 KDDRDRHLVEVKTLQTEATKYNDFKDAITELETTCSSQSTQIRQLQDRLVSDLSTFEKMN 345
Query: 215 YAKELED-----MNLKQATELKKLRQNNDVQSLLKKENELLQSK 253
E ED ++LK E +L+ + K N +L+ K
Sbjct: 346 ---EYEDQKQSIIDLKSRVEEAELKLVEGEKLRKKLHNTILELK 386
>7298332 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1409
Score = 52.4 bits (124), Expect = 2e-06
Identities = 65/286 (22%), Positives = 124/286 (42%), Gaps = 50/286 (17%)
Query: 7 IKEKPLESLDA-----DQLRRRVLTLQYKYTTLQNEYEISKLS----------SERETYS 51
I K +E +A +Q+++R++T++ YT +Q+ E + +E+E
Sbjct: 373 IIRKEIEEYEALVKKREQIKKRLVTVESAYTEIQSTMENTNKQRKKDKAQIEKNEKELED 432
Query: 52 LQNKYDKSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNE 111
L +K+ E+E+ K + L + L EEL+ + A E K L + + L +E
Sbjct: 433 LHKLPEKNQREIEDCNKKLESLEVSKVTLNEELEKQQA---ELTKTTAPLTEKRLKLSDE 489
Query: 112 VNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIR----Y 167
+V L K+++ + EV E IL Q ET ++ E ++
Sbjct: 490 -------LVGLKEKVNTAKGEVQ--------VFESQLKILKQAETTESRKYETLKSSYEQ 534
Query: 168 LQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNL--- 224
Q+ L+EK + EL+ S TE A ++K +KE+ N + + +
Sbjct: 535 SQKSLEEKVTRVDELKE-----SIPRMKTEIASKSAEVDKMVKEERNLSMQCNKLRTEIN 589
Query: 225 KQATELKKLRQNNDVQSLL---KKENEL--LQSKLDQLNSLQKKFE 265
++++ ++ R NN V L K E ++ + +L L + K++
Sbjct: 590 ERSSVMQAQRSNNKVLDFLMRMKMEGKIPGILGRLGDLGGIDAKYD 635
>7296991 [DY] KOG0977 Nuclear envelope protein lamin intermediate filament
superfamily
Length = 622
Score = 52.4 bits (124), Expect = 2e-06
Identities = 86/368 (23%), Positives = 158/368 (42%), Gaps = 52/368 (14%)
Query: 23 RVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDT-----------K 71
RV L+ + + L E + ++ + RET +++N ++ + E L DT K
Sbjct: 71 RVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIK 130
Query: 72 ILYEENIKLKEELKSKDALPKEDEKIITTLRTQV---VSLKNEVNLKEQRIVELAHKLSS 128
L+EEN +LK +L K K TT V S NE+N K + KL+
Sbjct: 131 RLWEENEELKNKLDKKT-------KECTTAEGNVRMYESRANELNNKYNQANADRKKLNE 183
Query: 129 KQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTS 188
NE +E ++ + E + L Q I+ L++EL K+ ++ S + +
Sbjct: 184 DLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKD----QIHSQEIN 239
Query: 189 ASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENE 248
S R TE + L+ +L + L+++ + +++ R +++QSL + + +
Sbjct: 240 ESRRIKQTEYSEIDGRLSSEYDAKLK--QSLQELRAQYEEQMQINR--DEIQSLYEDKIQ 295
Query: 249 LLQSKLDQL-NSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDV---ITELNMLQ 304
LQ + NS K E L VR+D N N++ +LN
Sbjct: 296 RLQEAAARTSNSTHKSIEELRSTR------------VRIDALNANINELEQANADLNARI 343
Query: 305 RENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELE---Q 361
R+ LD + + ++ +L E+ R ++ K+Y+ ++++K ++ +LE
Sbjct: 344 RDLERQLDNDRERH--GQEIDLLEKELIRLREEMTQQLKEYQ-DLMDIK-VSLDLEIAAY 399
Query: 362 QKLLSFEE 369
KLL EE
Sbjct: 400 DKLLVGEE 407
>SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 658
Score = 52.0 bits (123), Expect = 3e-06
Identities = 92/405 (22%), Positives = 163/405 (39%), Gaps = 72/405 (17%)
Query: 23 RVLTLQYKYTTLQNEYEISKLS--SERETYSLQNKYDKSMNELENALKDTKILYEENIKL 80
R L L K TT Q + +L + E ++ N+ + +++ +L +K L + I
Sbjct: 96 RSLQLSVKKTTRQQKTLDGQLLILKDNERTTISNRCAELDSQVPLSLGVSKALLDYVIFC 155
Query: 81 KEE-----LKSKDALPKEDEKIITTLR-----TQVVSLKN--EVNLKEQRIVELAHKLSS 128
+E L L K ++I +LR Q+ LK E +K + L H S
Sbjct: 156 HQEESFWPLSEPANLKKRFDEIFESLRYAKALDQIKGLKRDQETQVKVDQAT-LTHYRSD 214
Query: 129 KQNEVTNAIESMKLEIEGSG---NILHQHETQINKHVEEIRYLQQEL----KEKENLISE 181
K+ E ++L + S + + ++++ + E LQ EL +E E +
Sbjct: 215 KERA-----EKIELRVHESLKRISCIRSKVEELDQEITETARLQDELFKSTEEYEQQMIT 269
Query: 182 LRSVQTSASHRNNSTEELQDLAVLNKTLKEQL-----NYAKEL-EDMNLKQATELKKLRQ 235
+R +++ + N + +L+ + E L N+A+++ E+ L ++ E K+
Sbjct: 270 IRHLESQSDIINTTINDLKSQMTITDESSEDLEKLHSNFAEKVKEEQELYKSLEKKR--- 326
Query: 236 NNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQ------------EKITQWGI 283
+D++SLLK ELL+ L +Q + ESLE + +I + GI
Sbjct: 327 -SDLESLLKSRRELLEKLTGDLGKIQGEIESLEKLKVKKSTMINEIVHRYNINEINEEGI 385
Query: 284 VRLDGKFK---NPNDVITELNMLQRE-----------------NTFLLDTNSKLQIDFNQ 323
+ K+ N N I+ + +R+ N + + NS L+
Sbjct: 386 MTEVSKYASLVNKNYEISSGKLKERQVAVRARIEGIKAHEMFLNNRVSEINSSLEKQLTT 445
Query: 324 MSMLNDEMAI---ERNQLLDLNKDYETSILNLKRLNHELEQQKLL 365
L I + Q D KD E S L +K L E E + LL
Sbjct: 446 QKELRSRFEILFPVKLQREDFTKDVEKSDLWIKSLRQEYESKNLL 490
>Hs20484473 [S] KOG4725 Uncharacterized conserved protein
Length = 653
Score = 52.0 bits (123), Expect = 3e-06
Identities = 75/324 (23%), Positives = 134/324 (41%), Gaps = 33/324 (10%)
Query: 23 RVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKILYEENI-KLK 81
R LQ++ E + + T SL+ + +E +K + ++E + K+
Sbjct: 193 REAVLQWRLQQTIKEQALLNAHVTQVTESLK-QVQLEQDEYAKHIKGERARWQERMWKMS 251
Query: 82 EELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMK 141
E ++ K D I L+ + LKN+ +A LS VT+ +E ++
Sbjct: 252 VEARTLKEEKKRDIHRIQELKRSLSELKNQ----------MAEPLSLAPPAVTSVVEQLQ 301
Query: 142 LEIEGSGNILHQHETQINKHVEEIRYLQQELKE-KENLISELRSVQTSASHRNNSTEELQ 200
E + + E ++ VE + L KE K+ L + +Q + R EL+
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSVLSKEQKQRLQEQEERLQEQEAQR---VRELE 358
Query: 201 DLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSK----LDQ 256
L N+ L+EQ +E + KQ L+K + L+KE E LQ + DQ
Sbjct: 359 RLCEQNERLREQQKMLQEQGERLQKQEQRLRKQEER------LQKEEERLQKQEKRLWDQ 412
Query: 257 LNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSK 316
L KK + L+ + +E++ + +LD + P +LN ++ L +
Sbjct: 413 EERLWKKEDRLQKQ----EERLVLFQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 317 LQIDFNQMSMLNDEMAIERNQLLD 340
LQ ++ + E A +RNQ L+
Sbjct: 469 LQEKLDEEHL---EAASQRNQQLE 489
>CE04916 [KRT] KOG4572 Predicted DNA-binding transcription factor interacts
with stathmin
Length = 1330
Score = 52.0 bits (123), Expect = 3e-06
Identities = 74/322 (22%), Positives = 141/322 (42%), Gaps = 25/322 (7%)
Query: 33 TLQNEYEISKLSSERETYSLQNKYDKSMNEL--ENALKDTKILYEENIKLKEELKSKDAL 90
T+Q E + +LS + + ++ + + + A +D +I+ + KLK +K
Sbjct: 713 TVQLEDAVKRLSKMQNIVANMTPRNEKLFKYLHQTAPRDFEIIIHDGDKLKNRVK----- 767
Query: 91 PKEDEKIITTLRTQVVSLKNEVNLKEQRIVEL--AHKLSSKQNEVTNAIESMKLEIE-GS 147
E + + +L T++ + K+ + E ++ E+ +HK +N I+ M +E E +
Sbjct: 768 --ELGESVESLETELENKKSTESNLEAKLAEMTVSHK-KEIENTQAECIKRMSVEFELMT 824
Query: 148 GNILHQHETQINKHVEEIRYLQQELKEKENLISE--LRSVQTSASHRNNSTEELQDLAVL 205
++ Q + QI EI L+ +L EK+N+ E LR+ S ++ T E++ A L
Sbjct: 825 DSMSRQSKEQIESKDREIEELKAKL-EKQNIAHEKALRNDPYSEEYKRTLTAEIR--AEL 881
Query: 206 NKTLKEQLNYAKELEDMNLKQA--TELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKK 263
K K+++ + + +A + K L N V L ENE KL+ +N +++
Sbjct: 882 EKEFKQRIEVITKAVECKKDEAFARQEKTLEIENRV---LSSENESKSKKLEAMNREKEQ 938
Query: 264 FESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENT--FLLDTNSKLQIDF 321
ESL + + + ++ ++ D + +T LDTN L ID
Sbjct: 939 LESLIRQMPEGEVILDEFNALKESQPSAQIKDRFAAIRSRMERSTDGKCLDTNKVLLIDN 998
Query: 322 NQMSMLNDEMAIERNQLLDLNK 343
++ ER Q D+ K
Sbjct: 999 ILKVHKLQQLVNEREQYRDVIK 1020
>7292323 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 1381
Score = 52.0 bits (123), Expect = 3e-06
Identities = 113/515 (21%), Positives = 198/515 (37%), Gaps = 74/515 (14%)
Query: 127 SSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQ 186
SS N +N + ++ L Q ++ + E + L++EL +K+ +LR
Sbjct: 241 SSSSNSESNHLAVECADLRSKNRKLRQ---ELEEKSENLLELREELDDKKARFDKLRQES 297
Query: 187 TS-------ASHRNNSTEELQDLAVLNKTLKEQLN-YAKELEDMNLKQATELKKLRQNND 238
AS + + L++ A L+ ++ Y ++L D + ++ +++LR++N
Sbjct: 298 QEWFTEAKRASAYRDEVDILRERAERADRLEVEVQKYREKLGDSDFYKS-RVEELREDNR 356
Query: 239 VQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVIT 298
V L + E+L+ +L + + SLE E I ++KI + R D +++
Sbjct: 357 V---LLESKEMLEEQLQRYRKRSEHAISLESEIIKYKQKINDMALER-DVDRSKLEELLE 412
Query: 299 ELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLD-LNKDYETSILNL----K 353
E + LQ + NS + +D S D+ N L + L + +T L L +
Sbjct: 413 ENSQLQ---LVARNLNSTMDLD-KSFSENEDDCNSGDNSLSEQLTNNAQTRALKLELENR 468
Query: 354 RLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDLTNE 413
RL LEQ K SF E +Q+ + I Q +L
Sbjct: 469 RLTAALEQLKESSFHESTSKMLELEKEKKKLSLKI---EQMQEN--INRLTQQNVELEGV 523
Query: 414 LKRLNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANILEQK 473
K EE K D + R+K + + + + K L +
Sbjct: 524 FKNALEENKKLQDAVDNRQKSYDRQSLE-READRQKLSDAEQHVETLNKEKQRIQTLNES 582
Query: 474 IL----DLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALLEKENSDLLSGIETDAIPRSV 529
I DL L E K + L E Y+ K + L K+ +
Sbjct: 583 IQRRADDLERLAESKTKEL---------EQYLEKSRQYELTKQK---------------L 618
Query: 530 YDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAVNSL---------LGFKLEFL 580
Y+ I+ + E+E S K+ ++LKE +KS++ +++N L LG LE
Sbjct: 619 YE-IEARVSTYERENASLLKEVSKLKEGSEQKSVQLDDSINRLDVQSKELQKLGKALEDS 677
Query: 581 AHGKVKLVSCYQPN-----KYIIADLQSNTLKSDL 610
KLV + N + II +TL++DL
Sbjct: 678 EQVHQKLVELEKQNQELASQRIIDQEMISTLRNDL 712
Score = 51.6 bits (122), Expect = 4e-06
Identities = 82/387 (21%), Positives = 171/387 (43%), Gaps = 56/387 (14%)
Query: 2 SLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEY-----EISKLSSERETYSLQ--- 53
S T ++++ +S + ++++ ++ + +T + E E+SKL E S+Q
Sbjct: 596 SKTKELEQYLEKSRQYELTKQKLYEIEARVSTYERENASLLKEVSKLKEGSEQKSVQLDD 655
Query: 54 --NKYD---KSMNELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSL 108
N+ D K + +L AL+D++ ++++ ++L+++ + + D+++I+TLR +V+
Sbjct: 656 SINRLDVQSKELQKLGKALEDSEQVHQKLVELEKQNQELASQRIIDQEMISTLRNDLVT- 714
Query: 109 KNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQH-------ETQINKH 161
L +K +V N +E + L E G + +H + K
Sbjct: 715 ---------------GTLVTK--KVRNNLEKLGLADEEPGELNVEHVVEKLVRNPETFKT 757
Query: 162 VEEIRY-LQQELKEKENLISELRSVQTSASHRNN--STEELQDLAVLNKTLKEQLNYAKE 218
V EI + +E E+E ++S HR + E+ +LA Q + ++E
Sbjct: 758 VREIMLNVTREQLEEEEREGGVKSDMCVLCHRQEIFTVEKNIELAATPAPAPAQPS-SQE 816
Query: 219 L---EDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQ 275
L + L A E +L + D + L+ EN L + L S + SL ++++LQ
Sbjct: 817 LRFEHKVRLSPARESAELTRIKDSNTQLQTENARLSVDVAALGS---QITSLNTQHVALQ 873
Query: 276 EKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIER 335
+Q + + ++ E++ LQ+E+ L LQ +Q+S + + ++
Sbjct: 874 LANSQLAAEK--------DSLLKEIDSLQQEHKHALQDQVTLQCLHDQLSAEYESLNKDK 925
Query: 336 NQLLDLNKDYETSILNLKRLNHELEQQ 362
QL +D + + + LEQ+
Sbjct: 926 EQLKAAVRDLRQELRDTREQQSALEQR 952
>YBL047c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1381
Score = 51.6 bits (122), Expect = 4e-06
Identities = 62/284 (21%), Positives = 116/284 (40%), Gaps = 38/284 (13%)
Query: 98 ITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQ 157
++ T++ +L N+VN ++ + + S+ + + MK I+ N L Q
Sbjct: 599 LSNATTEMANLSNQVNSLSKQ-ASITNDKKSRATQELKRVTEMKNSIQIKLNNLRSTHDQ 657
Query: 158 INKHVEEIR-YLQQELKEKENLISELR----SVQTSASHRNNSTEELQDLAVLNKTLKEQ 212
K E++ + Q KE E L +L + + S N T +LQ+ N LKEQ
Sbjct: 658 NVKQTEQLEAQVLQVNKENETLAQQLAVSEANYHAAESKLNELTTDLQESQTKNAELKEQ 717
Query: 213 LNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEMENI 272
+ L M ++L N+ Q +K+E ++ QL Q +L+ E
Sbjct: 718 IT---NLNSMTASLQSQL------NEKQQQVKQERSMVDVNSKQLELNQVTVANLQKEID 768
Query: 273 SLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMA 332
L EKI+ + +T+ L + + +++LQ + +S + ++
Sbjct: 769 GLGEKISVY---------------LTKQKELNDYQKTVEEQHAQLQAKYQDLSNKDTDLT 813
Query: 333 IERNQLLDLNKD-------YETSILNLKRLNHELEQQKLLSFEE 369
QL + N+ Y + L+ + +L Q+K SFE+
Sbjct: 814 DREKQLEERNRQIEEQENLYHQHVSKLQEMFDDLSQRK-ASFEK 856
>SPBC146.03c [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1324
Score = 51.6 bits (122), Expect = 4e-06
Identities = 85/363 (23%), Positives = 168/363 (45%), Gaps = 56/363 (15%)
Query: 20 LRRRVLTLQYK-YTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKI--LYEE 76
L+ + + L +K + LQ E E R ++ D + LE+ + +K + EE
Sbjct: 251 LKEKGIDLNHKRFLILQGEVESIAQMKPR---AISEGDDGLLEYLEDIIGTSKYKPIIEE 307
Query: 77 NIKLKEELKSKDALPKEDE---KIITTLRTQVVSLKNEVN--LKEQRIVELAHKLSSKQN 131
N+ +EL + D + E E K++ + + ++ KN V LK++ ++L KQN
Sbjct: 308 NM---QELSNSDDICAEKESRLKLVLSEKAKLEDSKNSVLSFLKDE------NELFMKQN 358
Query: 132 EVTNAI----ESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQT 187
++ I + K ++ N+L+ E ++ H+E+ ++++ EK + LR +
Sbjct: 359 QLYRTILYETRNKKTLVQ---NLLNSLEGKLQAHLEKFEQTERDISEKNEEVKSLR--EK 413
Query: 188 SASHRNNSTEE---LQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLK 244
+A +N+ T E Q ++EQL + ++ LK++ E ++ SL
Sbjct: 414 AAKVKNDCTSEKKTRQSYEQQTVKIEEQLKFLLN-KEKKLKKSIEALSFEKSEAENSLSS 472
Query: 245 K--ENELLQSKLDQLNSLQKKFESLEMENI--SLQEKITQWGIVRLDGKFKNPNDVITEL 300
+++ L S++ L SL+ + E L +++I SLQ K T+ ++ K K + ++
Sbjct: 473 HDIDSQKLNSEIADL-SLRLQQEELSLDDIRKSLQGK-TEGISNAIEEKQKAMAPALEKI 530
Query: 301 NMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELE 360
N L E L ++++D +LN E DL D E+S +L +L ++ E
Sbjct: 531 NQLTSEKQIL-----QVELDM----LLNKEN--------DLINDVESSQSSLDKLRNDAE 573
Query: 361 QQK 363
+ +
Sbjct: 574 ENR 576
>CE02790 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase Citron
Length = 1286
Score = 51.6 bits (122), Expect = 4e-06
Identities = 80/409 (19%), Positives = 173/409 (41%), Gaps = 68/409 (16%)
Query: 3 LTPQIKE--KPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSM 60
LTP K K E + QL +V+ ++NE +LS + E ++N+ + +
Sbjct: 252 LTPVRKNASKIRELDEYHQLSAKVIEESMNDLKIKNETLTKELSDKTELVKMKNEELEDL 311
Query: 61 NE-----LENALKDTKILYEENIKL--------------KEELKSKDALPKEDEK----- 96
+ L ++ + TK L+EEN+KL + +++ D L +E EK
Sbjct: 312 RQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQELEKERDDA 371
Query: 97 ---------IITTLRTQVVSLKNEVNLKEQRIVELAHKL----------SSKQNEVTNAI 137
+ + ++ SL + + ++++I EL K+ S +NE++
Sbjct: 372 LADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQ 431
Query: 138 ESMKLEIEGSGNILHQHETQINKHVEEIR--YLQQELKEKENLISELRSVQTSASHRNNS 195
E KL+ G I+ + K ++E ++ +++ ++ +R +QTS +
Sbjct: 432 E--KLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKV 489
Query: 196 TEELQDLAVLNKTLKEQLNYAK-ELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKL 254
+E++ L N +++ + K E+++++L EL +L + + L +
Sbjct: 490 EQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAEKTKGKEDADHLRLTLSQRD 549
Query: 255 DQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTN 314
+L S +K + ++ +N +Q + + + + I E N+ R+ +
Sbjct: 550 SELRSAKKTIQEVKADNQKVQLMLVE---------VRQHQEKILEENVRLRKGM----AD 596
Query: 315 SKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKRLNHELEQQK 363
+ +I+ + S N + ER L ++ T L +L EL+++K
Sbjct: 597 ALAKIEEYKRSWQNSQETCER-----LERESATKEDKLDKLEEELQEKK 640
>7294443 [DZ] KOG0971 Microtubule-associated protein dynactin DCTN1/Glued
Length = 1265
Score = 51.6 bits (122), Expect = 4e-06
Identities = 57/269 (21%), Positives = 116/269 (42%), Gaps = 29/269 (10%)
Query: 14 SLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN-------A 66
+LD + + TLQ + + + E ++ E +QNK + ++ + +
Sbjct: 320 TLDKEMAEEKADTLQLELESSKERIEELEVDLELLRSEMQNKAESAIGNISGGGDSPGLS 379
Query: 67 LKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVEL---A 123
+ K L ++NI+LKE L L D + + L E+ +K + EL
Sbjct: 380 TYEFKQLEQQNIRLKETLVRLRDLSAHD-------KHDIQKLSKELEMKRSEVTELERTK 432
Query: 124 HKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELR 183
KLS+K +E+ + ++ +++ + E + + E+ L+ ++K E I++L
Sbjct: 433 EKLSAKIDELEAIVADLQEQVDAALGA----EEMVEQLAEKKMELEDKVKLLEEEIAQLE 488
Query: 184 SVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLL 243
+++ S EL+ L+E+L+ A + L++ + + D +
Sbjct: 489 ALEEVHEQLVESNHELE------LDLREELDLANGAKKEVLRERDAAIETIYDRD--QTI 540
Query: 244 KKENELLQSKLDQLNSLQKKFESLEMENI 272
K EL+Q DQL L+ + S E E++
Sbjct: 541 VKFRELVQKLNDQLTELRDRNSSNEKESL 569
>Hs4505983 [R] KOG0249 LAR-interacting protein and related proteins
Length = 1202
Score = 51.2 bits (121), Expect = 5e-06
Identities = 65/374 (17%), Positives = 160/374 (42%), Gaps = 41/374 (10%)
Query: 2 SLTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMN 61
+L +++E+ +L+ L L +K + E K + + ++ + + +
Sbjct: 173 ALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPS 232
Query: 62 ELENALKDTKILYEEN----IKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQ 117
D + +EE+ I+L+E + + + ++ + +L + V L+ +++ +
Sbjct: 233 TSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARK 292
Query: 118 RIVELAHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKEN 177
+++ + Q +V A+ + K ++E L + + + L +L EN
Sbjct: 293 DLIKSEEMNTKLQRDVREAM-AQKEDMEERITTLEKRYLAAQREATSVHDLNDKL---EN 348
Query: 178 LISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNN 237
I+ S+ +N +E +LA + L++ L A+ L ++ + A + L +
Sbjct: 349 EIANKDSMHRQTEDKNRQLQERLELA--EQKLQQTLRKAETLPEVEAELAQRVAALSKAE 406
Query: 238 DVQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVI 297
+ +++ ++++L++ N E++ +EK+ + RL +D +
Sbjct: 407 ERHGNIEERLRQMEAQLEEKNQ--------ELQRARQREKMNEEHNKRL-------SDTV 451
Query: 298 TELNMLQRENTFLLDTNSKLQIDFNQ-MSMLNDEMAIERN------QLLDLNKDYETSIL 350
+L L ++N +LQ+ + M+ L D+ ++ R QL + D + +L
Sbjct: 452 DKL---------LSESNERLQLHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVL 502
Query: 351 NLKRLNHELEQQKL 364
N++ L EL+ +L
Sbjct: 503 NIEALRAELDHMRL 516
>SPCC364.04c [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 633
Score = 50.8 bits (120), Expect = 6e-06
Identities = 75/348 (21%), Positives = 144/348 (40%), Gaps = 43/348 (12%)
Query: 29 YKYTTLQNEYEISKLSSE-RETYSLQNKYDKSMNELENALKDTKILYEENIKLKEELKSK 87
YK +N I KL+S+ RE + Q +D ++ E+A D E + EL
Sbjct: 187 YKDMEQENASTIQKLTSKIRELQASQLDHDLQASQNESAGLDVNAKSAEVNAILSELDDA 246
Query: 88 DALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEVTNAIESMKLEIEGS 147
+ KII L+ ++ LK N KEQ+ LS++Q + + ++S+ ++
Sbjct: 247 N-------KIIVELQAEIAVLKQ--NTKEQKSGSSQDDLSNQQKQQLDFMDSLNKKLSTE 297
Query: 148 -GNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLN 206
+I ++ H I+ L+ E+KE + E ++ S + EL L +
Sbjct: 298 LESIKEASRKEMETHCATIQTLENEVKEARKVKEESLTLANKFSDYDEIKRELSVLKQIE 357
Query: 207 KTLKEQLNYAKELEDMNLKQ----ATELKKLRQNN----DVQSLLKKENELLQSKLDQLN 258
+ + + LE LK+ + EL KLR N D + K+ L+ K +
Sbjct: 358 FSGEHATHENTSLESQLLKREKQLSEELAKLRSTNAQLTDRITQESKKASFLEQKASEQE 417
Query: 259 SLQKKFESLEMENISLQEKI----TQWGIVRLDGKFK--------NP---NDVITELNML 303
+ +K E ++ ++ ++ + T + G+ NP N + N +
Sbjct: 418 EVIRKLEK-DLADVDVEGSVYLSNTTYRREGTSGQLSPTSSIMGGNPSLFNGSVLSRNSV 476
Query: 304 QRENTFLLDTNSKLQIDF--------NQMSMLNDEMAIERNQLLDLNK 343
+ ++D + + F NQ+S ND++A+ ++L ++ K
Sbjct: 477 NETGSAIVDVIKQQRDRFRRANVTLVNQVSAANDKIALLESKLEEVEK 524
>Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2349
Score = 50.8 bits (120), Expect = 6e-06
Identities = 123/664 (18%), Positives = 252/664 (37%), Gaps = 112/664 (16%)
Query: 8 KEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERE---TYSLQNKYDKSMNELE 64
K +P D D L ++ + + L+ + S + E+ SL+ +K E
Sbjct: 925 KGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTE 984
Query: 65 NALKDTKILYEENIKLKEELKSK-DALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELA 123
K+ ++ +E+ + + +L+ K + KE +++ R + S+ EQ++ EL
Sbjct: 985 EVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESM-------EQQLSELK 1037
Query: 124 HKLSSKQNEVTNAI------------------ESMKLEIEGSGN-----ILHQHETQ--- 157
LSS QNEV A+ E K+ +E +LH + +
Sbjct: 1038 KTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQ 1097
Query: 158 -INKHVEEIRYLQQELKE-KENLISELRSVQTSASHRNNSTEE--------LQDLAVLNK 207
+ V ++ ++Q L+E + S+L + S R ++ +DL N+
Sbjct: 1098 AAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNR 1157
Query: 208 TLKEQLNYAKELED-------------MNLKQATELKKLRQNNDVQSLLKKENELLQSKL 254
L +Q+ ++L D +N+ + E K Q ++ +++E E+ +++
Sbjct: 1158 LLHDQI---EKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRF 1214
Query: 255 D--QLNSL--QKKFESLEMENISLQE---------KITQWGIVRLDGKFKNPN--DVITE 299
+ Q+ SL +++ E LE E L++ ++T + + + K +V+ E
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVME 1274
Query: 300 LNMLQRENTFLLDTN--------SKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILN 351
N + RE L+ + KL++D + N E++ + L K E +
Sbjct: 1275 TNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKR 1334
Query: 352 LKRLNHEL----------EQQKLLSFEECXX---XXXXXXXXXXXXXXXXTPGDQVNASN 398
K N L E +KLLS +E + N N
Sbjct: 1335 WKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQN 1394
Query: 399 IIEGYKNQTEDLTNELKRLNEELSKTDDKIQKR-------RKITNDLGISYSQ-XXXXXX 450
+I+ K + E + + ++L IQ++ +KI Y +
Sbjct: 1395 LIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDK 1454
Query: 451 XXXXXXXXXXSATKNHANILE-QKILDLTSLKEKKVRILQLRDNPLLKEHYIRKEKLALL 509
+ H ++ E Q++ + + E K + L+ + L K ++ + L
Sbjct: 1455 VMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNL 1514
Query: 510 EKENSDLLSGIETDAIPRSVYDRIKHDMKLLEKEIFSANKKTTRLKEVFNKKSLEFIEAV 569
+++ L S E + + + DR + +L ++ + ++ TR V K + + V
Sbjct: 1515 QEQTVQLQS--ELSRLRQDLQDRTTQEEQL--RQQITEKEEKTRKAIVAAKSKIAHLAGV 1570
Query: 570 NSLL 573
L
Sbjct: 1571 KDQL 1574
>Hs20373153 [Z] KOG0161 Myosin class II heavy chain
Length = 2567
Score = 50.8 bits (120), Expect = 6e-06
Identities = 84/385 (21%), Positives = 164/385 (41%), Gaps = 50/385 (12%)
Query: 17 ADQLRRRV--LTLQYKYTTLQNEYEISK---LSSERETYSLQNKYDKSMNELENALKDTK 71
A QL+R+ LT + T + E + S+ L +++ + LQ + E L++
Sbjct: 1571 AHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREK- 1629
Query: 72 ILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEV-------NLKEQRIVELAH 124
+ +EN ++ EL K+ E+ + L+ QV L++ +L E + L
Sbjct: 1630 -VTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKE 1688
Query: 125 KLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRS 184
+L ++ +A+E K++ + I + + +E R Q K++E+ EL
Sbjct: 1689 RLWKLES---SALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELED 1745
Query: 185 VQTSASHRNNSTE---------------ELQDLAVLNKTLKEQLNYAKELEDMNLKQATE 229
V+ S R + E E QDL L TL +Q+ + D+ + +
Sbjct: 1746 VRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDF--DVEKRLRRD 1803
Query: 230 LKKLRQN-NDVQSLL-----------KKENELLQSKLDQLNSLQKKFESLEMENISLQEK 277
L++ +DVQ LL K+E E + S+L+Q S K E+L+ + + +
Sbjct: 1804 LRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQ--SEAKCEEALKTQKVLTADL 1861
Query: 278 ITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQ 337
+ L+ +N + V +L LQ E LL + Q D N++ + ++ +
Sbjct: 1862 ESMHS--ELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAA 1919
Query: 338 LLDLNKDYETSILNLKRLNHELEQQ 362
+ ++ + + K+ H+L++Q
Sbjct: 1920 DIGQIQELQLQLEEAKKEKHKLQEQ 1944
>CE21149 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC superfamily
Length = 1298
Score = 50.8 bits (120), Expect = 6e-06
Identities = 75/352 (21%), Positives = 152/352 (42%), Gaps = 32/352 (9%)
Query: 16 DADQLRRRVLTLQYKYTTLQNEYE--ISKLSSERETYSLQNKYDKSMNELENALKDTKIL 73
+ ++ +++ + + T Q E E +SKL E + K + NEL+ +K+ K +
Sbjct: 678 EINEFSKKLENMTLSFPTEQEELEKLVSKLEKEE---IIIVKAEGQANELQRIVKELKEV 734
Query: 74 YEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLSSKQNEV 133
E+N KL E+ + + ++EK + T V+ K ++ Q V + +L + E
Sbjct: 735 REKNRKLSTEMAEEKSNLSKNEKQLET-----VNAKLKLAEDLQTDVGVIQQLYEQTEEN 789
Query: 134 TNAIESMKLEIEGSGNILHQHETQINKHV----EEIRYLQQELKEKENLISELRSVQTSA 189
E + E + S + + T++ K V EE R + QE +E + E +Q+
Sbjct: 790 EKRYEQLVSESDSSDGLSY---TELRKKVEDKDEEYRKIVQEGEELQKCSEERNKLQSKL 846
Query: 190 SHRNNSTEELQDLAVLNKTLKEQL-NYAKELED----MNLKQATEL--KKLRQNNDVQSL 242
+ L + A EQL KE+++ ++ K+ +L + ++++ +++
Sbjct: 847 NELGTHRVSLGEAAAQAGAFAEQLETKIKEIQECITAISQKRNEDLPDAQFKKDDLTRNV 906
Query: 243 LKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNM 302
KE E ++++ ++ ++K+ + SL +K+ + G+ K N I LN
Sbjct: 907 SSKEEEKKKAEM-EVQMMKKELDQKIFHRKSLFKKVQEGGLCERQLMDKENN--IATLNA 963
Query: 303 LQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQLLDLNKDYETSILNLKR 354
EN + + D + +I ++QL + E I LKR
Sbjct: 964 SLEENQ---QRQKRFEEDLRSFDSSHQRESILKDQLTRM--IIENKIKELKR 1010
>CE04618 [Z] KOG0161 Myosin class II heavy chain
Length = 1956
Score = 50.8 bits (120), Expect = 6e-06
Identities = 111/526 (21%), Positives = 225/526 (42%), Gaps = 74/526 (14%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
Q++++ S + D +R R+ T + + N+ +LS E + QN +K+ +E
Sbjct: 887 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMR-DRLSEEEQ----QN--EKNNDERRK 939
Query: 66 ALKDTKILYEENIKLKEELKSKDALPKED-EKIITTLRTQVVSLKNEVN--LKEQRIVEL 122
++ + L EE ++ +E+ + K L K + ++ + L ++V L++ + LKE+R++E
Sbjct: 940 QMETVRDL-EEQLEQEEQARQKLLLDKTNVDQRLRNLEERLVELQDAYDKLLKEKRLLEE 998
Query: 123 AHKLSSKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISEL 182
++EG L HE + V+ L+ +L E E ++
Sbjct: 999 --------------------KVEGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRE 1038
Query: 183 RSVQTS-ASHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQS 241
R ++ H+ EL+D L E++ +EL + +K+ EL+ D +S
Sbjct: 1039 RQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 1095
Query: 242 ----LLKKENELLQSKLDQLNSLQKKFESLEME-NISLQEKITQWGIVRLDGKFK-NPND 295
L++K+ +Q+ +D+L E +E E N + ++T+ +V K K + D
Sbjct: 1096 ANVTLMQKQMRDMQTTIDELR------EDMETERNARNKAEMTRREVVAQLEKVKGDVLD 1149
Query: 296 VITELNMLQ----RENTFLLDTNSKL-QIDFNQMSMLNDEMAIERNQLLDLNKDYETSIL 350
+ E MLQ R++ + T + QI + ++ A Q+ +L+ E
Sbjct: 1150 KVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH-- 1207
Query: 351 NLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQVNASNIIEGYKNQTEDL 410
K+ +LE+Q+ + +E +++ ++++E N E
Sbjct: 1208 --KKQRSQLEKQQNQADQE-RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE-- 1262
Query: 411 TNELKR-LNEELSKTDDKIQKRRKITNDLGISYSQXXXXXXXXXXXXXXXXSATKNHANI 469
++E KR L ++L ++ D++ ++ + +++ + +
Sbjct: 1263 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFAN-----------MQRRLATAEGQIQE 1311
Query: 470 LEQKILDLTSLKEKKV-RILQLRD--NPLLKEHYIRKEKLALLEKE 512
L ++I + T LK + R QL D N LL E + A LEKE
Sbjct: 1312 LNEQIQEETRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKE 1357
>At5g60930 [Z] KOG0244 Kinesin-like protein
Length = 1288
Score = 50.8 bits (120), Expect = 6e-06
Identities = 86/394 (21%), Positives = 156/394 (38%), Gaps = 62/394 (15%)
Query: 44 SSERETYSLQNKYDKSMNELENALKDTKILYE-ENIKLKEELKSKDALPKEDEKII---- 98
S + E L NKY + ELE L K L + N + ++ S D P+ + +
Sbjct: 459 SCQNEDVGLVNKYVSKIQELEGELLHIKNLKKTSNHQYSDD--SYDVGPRSNNVLFPSSN 516
Query: 99 --TTLRTQVVSLKNEVNLKEQRI--VELAHKLSSKQNEVTNAIESMKLEIE----GSGNI 150
+ +V+ + +E+ +E+ I L KL + E+ +E + E++ G ++
Sbjct: 517 ESSDCEDKVMDVTDELEFQEKEIEHCSLQEKLDMELKELDKRLEEKEAEMKRFSSGGTSV 576
Query: 151 LHQH-ETQINKHVEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTL 209
L QH E ++ +E R LQ+E++ + ++ + S + + L
Sbjct: 577 LKQHYEKKVYDLEQEKRALQREIEGLRHNLASIPSGPGDGAQK----------------L 620
Query: 210 KEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENELLQSKLDQLNSLQKKFESLEM 269
KE+ Y ++L + T++ L++ D Q+ L ++ Q D LQ + ++
Sbjct: 621 KEE--YVQKLNTLE----TQVSVLKKKQDAQAQLMRQK---QKSDDAAIKLQDEIHRIKS 671
Query: 270 ENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLND 329
+ + LQ+KI Q K +V+ +L R N + +M L
Sbjct: 672 QKVQLQQKIKQESEQFRAWKASREKEVM-QLKKEGRRNEY-------------EMHKL-- 715
Query: 330 EMAIERNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXT 389
MA+ + Q L L + E + KRL L+ +K S E
Sbjct: 716 -MALNQKQKLVLQRKTEEASQVTKRLKELLDNRK-ASSRETLSGANGPGTQALMQAIEHE 773
Query: 390 PGDQVNASNIIEGYKNQTED---LTNELKRLNEE 420
V + Y+ QTE+ + E+ RL EE
Sbjct: 774 IEVTVRVHEVRSEYERQTEERARMAKEVARLREE 807
>YJL074c [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1230
Score = 50.4 bits (119), Expect = 8e-06
Identities = 80/374 (21%), Positives = 156/374 (41%), Gaps = 69/374 (18%)
Query: 14 SLDADQLRRR-VLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDTKI 72
+LD D+ +R VLT Y ++++ ++L S + ++++ K + EL+ +
Sbjct: 660 TLDGDRADKRGVLTGGYL-----DQHKRTRLESLKNLNESRSQHKKILEELDFVRNE--- 711
Query: 73 LYEENIKLKEELKSKDALPKEDEKIITTL---RTQVVSLKNEVNLKEQRIVELAHKLSSK 129
L + + K+ + + + + E ++T + RT + + KNE + E+ + + KL
Sbjct: 712 LNDIDTKIDQVNGNIRKVSNDRESVLTNIEVYRTSLNTKKNEKLILEESLNAIILKLEKL 771
Query: 130 QNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTSA 189
T A E + ++L + +++++K +EKE L S + + +
Sbjct: 772 NTNRTFAQEKLNTF---ENDLLQEFDSELSK------------EEKERLESLTKEISAAH 816
Query: 190 SHRNNSTEELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLKKENEL 249
+ N +++ L+ + +L +L E K + Q ND++S + + +
Sbjct: 817 NKLNITSDALEGITTTIDSLNAEL---------------ESKLIPQENDLESKMSEVGDA 861
Query: 250 LQSKL-DQLNSLQKKFESLEM--ENISLQEKITQWGIVRLDGKFKNPNDVITELNMLQR- 305
L D+L LQ + ES+E EN L+ Q I L + N ++ + N QR
Sbjct: 862 FIFGLQDELKELQLEKESVEKQHENAVLELGTVQREIESLIAEETNNKKLLEKANNQQRL 921
Query: 306 -----------------ENTFLLDTNSKLQIDFNQMSML------NDEMAIERNQLLDLN 342
+ T L+ +LQ ++ +L ND I +QLL
Sbjct: 922 LLKKLDNFQKSVEKTMIKKTTLVTRREELQQRIREIGLLPEDALVNDFSDITSDQLLQRL 981
Query: 343 KDYETSILNLKRLN 356
D T I LK +N
Sbjct: 982 NDMNTEISGLKNVN 995
>HsM4885113 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1288
Score = 50.4 bits (119), Expect = 8e-06
Identities = 70/294 (23%), Positives = 131/294 (43%), Gaps = 45/294 (15%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNE-YEISKLSSERETYSLQNKYDKSMNELENAL 67
EK ++L+ ++ + ++ TL+NE + + Y LQ + + + E
Sbjct: 292 EKEKDALEGEK------NIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIH 345
Query: 68 KDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLK---NEVNLKEQRIVELAH 124
+DTK + E++ L E+K+K+ K+ EK + + + K +++L++ ++ E
Sbjct: 346 EDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLK 405
Query: 125 KLSSKQNEVTNAIESMKLEIE-------GSGNILHQHETQIN-----------KHVEEIR 166
+SK ++ ++ K ++E S NI+++ T+ N K E +
Sbjct: 406 HATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMD 465
Query: 167 YLQQEL----KEKENLISEL----RSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKE 218
L+QE KEKE+ EL +SV + S + + EL + T QL AKE
Sbjct: 466 SLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKE 525
Query: 219 LEDMNLKQATELKKLRQN--NDVQSLLKKENELLQSK---LDQLNSLQKKFESL 267
L A+E K R+ D++ L + + L+ K L +L + F+SL
Sbjct: 526 A----LIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSL 575
>Hs7305205 [Z] KOG0244 Kinesin-like protein
Length = 1232
Score = 50.4 bits (119), Expect = 8e-06
Identities = 52/235 (22%), Positives = 109/235 (46%), Gaps = 29/235 (12%)
Query: 69 DTKILYEENIKLKEEL-KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVELAHKLS 127
DT + E ++ E +S DA + + ++V L + LKE LA K++
Sbjct: 489 DTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEA----LARKMT 544
Query: 128 SKQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQT 187
+++ I +Q++ I + E+ LQ KEKE L+ EL++ +
Sbjct: 545 QNDSQLQP--------------IQYQYQDNIKEPELEVINLQ---KEKEELVLELQTAKK 587
Query: 188 SASHRNNST---EELQDLAVLNKTLKEQLNYAKELEDMNLKQATELKKLRQNNDVQSLLK 244
A+ S + LQ+L LK++LN +L + LK++TE + N +++ +
Sbjct: 588 DANQAKLSERRRKRLQELEGQIADLKKKLNEQSKL--LKLKESTERTVSKLNQEIRMMKN 645
Query: 245 KENELLQSKLDQLNSLQKKFESLEMENISLQE--KITQWGIVRLDGKFKNPNDVI 297
+ +L++ + ++ + + E I L+E + Q+ +++L+ F+ ++V+
Sbjct: 646 QRVQLMRQMKEDAEKFRQWKQKRDKEVIQLKERDRKRQYELLKLERNFQKQSNVL 700
>Hs21361252 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1288
Score = 50.4 bits (119), Expect = 8e-06
Identities = 70/294 (23%), Positives = 131/294 (43%), Gaps = 45/294 (15%)
Query: 9 EKPLESLDADQLRRRVLTLQYKYTTLQNE-YEISKLSSERETYSLQNKYDKSMNELENAL 67
EK ++L+ ++ + ++ TL+NE + + Y LQ + + + E
Sbjct: 292 EKEKDALEGEK------NIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIH 345
Query: 68 KDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLK---NEVNLKEQRIVELAH 124
+DTK + E++ L E+K+K+ K+ EK + + + K +++L++ ++ E
Sbjct: 346 EDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLK 405
Query: 125 KLSSKQNEVTNAIESMKLEIE-------GSGNILHQHETQIN-----------KHVEEIR 166
+SK ++ ++ K ++E S NI+++ T+ N K E +
Sbjct: 406 HATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMD 465
Query: 167 YLQQEL----KEKENLISEL----RSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKE 218
L+QE KEKE+ EL +SV + S + + EL + T QL AKE
Sbjct: 466 SLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKE 525
Query: 219 LEDMNLKQATELKKLRQN--NDVQSLLKKENELLQSK---LDQLNSLQKKFESL 267
L A+E K R+ D++ L + + L+ K L +L + F+SL
Sbjct: 526 A----LIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSL 575
>At2g27170 [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1200
Score = 50.4 bits (119), Expect = 8e-06
Identities = 58/276 (21%), Positives = 115/276 (41%), Gaps = 36/276 (13%)
Query: 162 VEEIRYLQQELKEKENLISELRSVQTSASHRNNSTEELQDLAVLNKTLKEQLNYAKELED 221
+E + YL + L+E + ELR Q R + + + +K L + +++E
Sbjct: 227 IEVVHYLDERLRELDEEKEELRKYQQLDKQRKSL-----EYTIYDKELHDAREKLEQVEV 281
Query: 222 MNLKQATELKKLRQNND-VQSLLKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQ 280
K + E K+ + Q K +E L+ +L +L K+ E++E + +K T+
Sbjct: 282 ARTKASEESTKMYDRVEKAQDDSKSLDESLKELTKELQTLYKEKETVEAQQTKALKKKTK 341
Query: 281 WGIV------RLDGKFKNPNDVITELNMLQRENTFLLDTNSKLQIDFNQMSMLNDEMAIE 334
+ R+ G ++ ND + +LN ++RE L + AI+
Sbjct: 342 LELDVKDFQDRITGNIQSKNDALEQLNTVERE----------------MQDSLRELEAIK 385
Query: 335 RNQLLDLNKDYETSILNLKRLNHELEQQKLLSFEECXXXXXXXXXXXXXXXXXXTPGDQV 394
++K+ +TS KR+N ELE+ + +++ D
Sbjct: 386 PLYESQVDKENQTS----KRIN-ELEKTLSILYQKQGRATQFSNKAARDKWLRKEIED-- 438
Query: 395 NASNIIEGYKNQTEDLTNELKRLNEELSKTDDKIQK 430
+++ Q + L +E+ RLN +L++ D+ I+K
Sbjct: 439 -LKRVLDSNTVQEQKLQDEILRLNTDLTERDEHIKK 473
>7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2346
Score = 50.4 bits (119), Expect = 8e-06
Identities = 92/412 (22%), Positives = 172/412 (41%), Gaps = 66/412 (16%)
Query: 6 QIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELEN 65
++KE +ES + D L + +L + E + + T LQ+ + E
Sbjct: 173 ELKENRMES-ERDMLHKEILLISGDLNKSNAELQNIRREHTINTMQLQS----CLKEKTE 227
Query: 66 ALKDTKILYEENIKLKEELKSKDALPKEDE-KIITTLRTQVVSLKNEVNLKEQRIVELAH 124
+LK + YE+ +K EL SK + + K V LK E++ KE ++ E+
Sbjct: 228 SLKLMQEQYEQAVKTIGELTSKIEMQNDTAFKQNQATEEYVGKLKKELDAKE-KLFEIFK 286
Query: 125 KLSS----KQNEVTNAIESMKLEIEGS----GNILHQHETQINKHVEEIRYLQQELKEKE 176
S ++ E+ I +K +E + + Q ET KH E+ ++++ E
Sbjct: 287 STESDHLIQREELLQGISEIKRLLEEAEEQCAQLTEQMETMKQKHSAELDEQNKKIQAME 346
Query: 177 NLISELRSVQTSASHRNNSTEELQ---DLAVLNKTLKEQLN-------YAKELEDMNLKQ 226
++ + A N + Q AV ++ ++ L+ YAK E++ ++
Sbjct: 347 QELASANDLLKQARESNLESAICQLAPSAAVASRLIRSDLSLTELYSMYAKSSEELEMRN 406
Query: 227 AT------ELKKL------------RQNNDVQS-------LLKKENELLQSKLDQLNSLQ 261
+LK + +QN+D Q LL++ +ELLQ+KL L+
Sbjct: 407 CEIEQLKLQLKSIIAEISESAPILEKQNSDYQKMKETNSELLREHDELLQNKLCLERELE 466
Query: 262 KKFESL---EMENISLQEKITQWG---IVRLDGKFKNPNDVITELNMLQRENTFLLDTNS 315
+ +L + EN L++ T + LD N + + ++ + T L T+
Sbjct: 467 RALSTLNHNQNENKKLKQTHTDLSRQVCMLLD----ELNCIRAGVKHVRIQPTRQLPTSE 522
Query: 316 KLQIDFNQMSMLNDEMAIERN-QLLDLNKDYETSILNLKRLNHE---LEQQK 363
L I N ++ + E ++RN LL+++++ T +L N + LEQ K
Sbjct: 523 SL-ISDNLVTFSSIEELVDRNTYLLNMSREL-TELLEASEKNQDKMLLEQSK 572
>7303173 [DY] KOG0977 Nuclear envelope protein lamin intermediate filament
superfamily
Length = 621
Score = 50.4 bits (119), Expect = 8e-06
Identities = 78/356 (21%), Positives = 150/356 (41%), Gaps = 47/356 (13%)
Query: 23 RVLTLQYKYTTLQNEYEISKLSSERETYSLQNKYDKSMNELENALKDT-----------K 71
R+ L+ + + L E +++ + RET +L+ Y+K + L +T K
Sbjct: 63 RMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIK 122
Query: 72 ILYEENIKLKEEL--KSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVE-LAHKLSS 128
L+EEN LK L K+K+A E+ + R V+ K +L +++ E A +L+
Sbjct: 123 RLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELAL 182
Query: 129 KQNEVTNAIESMKLEIEGSGNILHQHETQINKHVEEIRYLQQELKEKENLISELRSVQTS 188
+ + ++ ++ ++E E Q EE+ + Q ++ R ++ S
Sbjct: 183 ENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEIS 242
Query: 189 ASHRNNSTEELQDLAVLNKTLKEQLNYAKEL--EDMNLKQATELKKLR--QNNDVQ--SL 242
S + L + L++Q + E++ L E++ L+ N Q +L
Sbjct: 243 EIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSAL 302
Query: 243 LKKENELLQSKLDQLNSLQKKFESLEMENISLQEKITQWGIVRLDGKFKNPNDVITELNM 302
+E L+++K+D LN+ K ++LE N L +I + N + TE
Sbjct: 303 ATEEVRLMRTKIDGLNA---KLQNLEDTNAGLNARIREL-----------ENLLDTE--- 345
Query: 303 LQRENTFLLDTNSKLQIDFNQMSMLNDEMAIERNQ---LLDLNKDYETSILNLKRL 355
QR N ++ ++LQ + DEMA + + L+D+ + I +L
Sbjct: 346 RQRHNQYIASLEAELQ-------RMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKL 394
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.310 0.129 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,656,337
Number of Sequences: 60738
Number of extensions: 1414318
Number of successful extensions: 9412
Number of sequences better than 1.0e-05: 118
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 127
Number of HSP's that attempted gapping in prelim test: 8383
Number of HSP's gapped (non-prelim): 564
length of query: 648
length of database: 30,389,216
effective HSP length: 113
effective length of query: 535
effective length of database: 23,525,822
effective search space: 12586314770
effective search space used: 12586314770
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)