ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV4990 good T KOG2137 Signal transduction mechanisms Protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV4990 1709335 1711635 767
(767 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL083w [T] KOG2137 Protein kinase 644 0.0
SPBP23A10.10 [T] KOG2137 Protein kinase 185 2e-46
7301728 [T] KOG2137 Protein kinase 129 1e-29
At1g71410 [T] KOG2137 Protein kinase 114 7e-25
At1g22870 [T] KOG2137 Protein kinase 77 1e-13
7294852 [T] KOG2137 Protein kinase 76 2e-13
CE27789 [T] KOG2137 Protein kinase 68 6e-11
7301824 [R] KOG1243 Protein kinase 63 1e-09
Hs8922218 [T] KOG2137 Protein kinase 62 3e-09
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 53 2e-06
YGR052w [T] KOG0583 Serine/threonine protein kinase 52 3e-06
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 52 4e-06
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 52 4e-06
At4g10390 [T] KOG1187 Serine/threonine protein kinase 51 8e-06
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 51 8e-06
>YGL083w [T] KOG2137 Protein kinase
Length = 804
Score = 644 bits (1662), Expect = 0.0
Identities = 335/727 (46%), Positives = 459/727 (63%), Gaps = 22/727 (3%)
Query: 1 MFWXXXXXXXXXXXXXNTPTFTAEPWSVYTGKPKXXXXXXXGGPIDKVSVFIFDKKQFES 60
MFW ++PTFTAEPWS+YTG+PK KVS+F+FDKKQFE+
Sbjct: 2 MFWSSKTGITSKYSFSSSPTFTAEPWSIYTGRPKSSSSSSPS----KVSIFMFDKKQFEN 57
Query: 61 YLLHYGIIKSKNSSHDKLFLNDAYTVLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVT 120
YLLHYGIIKSK+ S DK+ + +AY +LRNQ NNLAK KHPNIL LIEPLEEHSKNF+FVT
Sbjct: 58 YLLHYGIIKSKSGSRDKVLIQEAYEILRNQANNLAKLKHPNILTLIEPLEEHSKNFMFVT 117
Query: 121 EYVSGSLFNLFQEQDSVTSTFGEELLQSNDTNNLTIQRGILQVCQALDFIHNKTSSVHLD 180
E+V+ SL +F+E D F LQ + +N+ +QRGILQ+ ALDF+HN+ S VHL+
Sbjct: 118 EFVTSSLETVFRETDDEEQNF----LQGHVKDNIVVQRGILQLVNALDFVHNRASFVHLN 173
Query: 181 IQPRSVFVNENADWKLSGLGHLIKLPEGTNVGDFTIPQYDPRVPTFLQIDLNFAAPELVM 240
IQPR++F+NEN+DWK+SGLG+L+K+P GTN ++ +PQYDPRVP F+ + LN+ APE+V
Sbjct: 174 IQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLPQYDPRVPPFMHLQLNYTAPEIVF 233
Query: 241 EDTFSARSDXXXXXXXXXXXXXXXXXFLCENSKQSYRDQFTKFERKIASLSWDAVFQKVP 300
E+T + ++D F ENS Y+ ++ KFE KI+++SWD +F KVP
Sbjct: 234 ENTLTFKNDYFSLGLLIYFLYTGKDLFRSENSTSEYKLEYNKFESKISTMSWDNIFSKVP 293
Query: 301 QTLRFCLPRLMNRDIYSRYDNIVEFLDNDFFKDPLIQTLIFLDDLPTKNIDEKTIFLTGL 360
Q LR C+P+L+NRDIYSRYDNI LD++FF+DPL++TL FLDDLPTKN +EK +FL GL
Sbjct: 294 QKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNFLDDLPTKNNEEKYVFLEGL 353
Query: 361 ITLLPKYPAQLLQKKFXXXXXXXXXXXCSMKETADECLQINLEVILLIGKNLSQLSFTEK 420
+ LLP++P LLQKKF C+ K +D+C+ +L++I+ IG LSQLSF EK
Sbjct: 354 VNLLPEFPPALLQKKFLPILLELLSQFCAEKVVSDKCVGKSLDLIIKIGSTLSQLSFQEK 413
Query: 421 ITNHIIGSANGKVILEHGASGLIKHLSILQIKLKKDAFDKSLLKPLYEYTCESQENP--- 477
+ ++ AN V+L+ LI +L L+ K+K+ F +++LKPL+ Y E+
Sbjct: 414 VYPVLLSDANFPVLLKKATICLIDNLDTLKQKVKRSDFLENILKPLFNYVLHDSESDITV 473
Query: 478 NIQESLLNQLPIALETFDFATVKNFLSPLIQKLFTKTTSLTVKNACISCFQTMIQSNAMD 537
QE LL+Q+P+ALE DF TVK FL PL+ LFTKTTSLTVKN C++CFQ MI+ ++D
Sbjct: 474 VCQEKLLSQIPLALEVLDFPTVKQFLLPLLSNLFTKTTSLTVKNTCVTCFQIMIEHKSID 533
Query: 538 TYMIQETLFPLIKSMKSRDSRILMKFLEFFPHLYTAIQDKEELITESFIPLMFAFSMAPT 597
+Y ET+ PL KSMK+RD RIL K L+ F + I D E ++ + +PLM+ +SMA T
Sbjct: 534 SYTCSETVLPLFKSMKTRDPRILSKLLKLFETVPLIITD-EIVLVDQVLPLMWNYSMAST 592
Query: 598 LXXXXXXXXXXXXXXXXXQIQKRHVQQLKTEQSKSQELESKDFTKIIDTPIVPARTDTDN 657
L IQK H+ +L K ++ F K+I+ P + + D +
Sbjct: 593 LTKSQYSGYTKAINKMSSDIQKHHIAKL---DDKVNDIGEDAFHKVIE-PTIMKKEDPET 648
Query: 658 EISRSINVPVIKP---KASPSYQATGILXXXXXXXXXXXXXIRSGGPSRGVP-RSIRSPP 713
+++I V ++P K SY T L ++ +RG P R + SPP
Sbjct: 649 VAAKNIEVAAMQPVKKKTGSSYGET--LPQSKSILNSKPLNPKNALATRGFPTRILNSPP 706
Query: 714 QKPVKPT 720
Q P T
Sbjct: 707 QTPSSRT 713
>SPBP23A10.10 [T] KOG2137 Protein kinase
Length = 749
Score = 185 bits (470), Expect = 2e-46
Identities = 161/667 (24%), Positives = 274/667 (40%), Gaps = 67/667 (10%)
Query: 25 PWSVYTGKPKXXXXXXXGGPIDKVSVFIFDKKQFESYLLHYGIIKSKNSSHDKLFLNDAY 84
PW+VY+ K G ++VSVF FDKK + L + S L N
Sbjct: 31 PWTVYSASKK--------GTNEEVSVFTFDKKNLSTLL-------KRGSIDSNLKTNYVL 75
Query: 85 TVLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEE 144
+LR V++L++ +HP++LQ++EPLEE + FVT + L + + + S +G
Sbjct: 76 ELLRKDVSSLSRLRHPSLLQVVEPLEESKSSMSFVTRRIQSMLQDFIKSSNGGFSNYGSS 135
Query: 145 LLQSNDTNNLT---IQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGH 201
+ N L IQ+G+LQ+ L F+H +H +I+P SV V+ DWKL G
Sbjct: 136 ANGKSSGNALEEVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFS- 194
Query: 202 LIKLPEGTNVGDFTIPQYDPRVPTFLQIDLNFAAPELVMEDTFSARSDXXXXXXXXXXXX 261
+ + YD +P+ LQ ++F APE + + SD
Sbjct: 195 ---FSQSVESARYEFNDYDFGIPSSLQQSMDFLAPEYITHEIAGPESDVFSFGCLIYSIF 251
Query: 262 XXXXXFLCENSKQSYRDQFTKFERKIASLSWDAVFQKV---PQTLRFCLPRLMNRDIYSR 318
+ N+ +E++I SL+ + + L+ L + D R
Sbjct: 252 NKNQSIINANN------HLLSYEKEITSLNSPTFIESKNLPSENLKSLLKETLAVDPKQR 305
Query: 319 YDNIVEFLDNDFFKDPLIQTLIFLDDLPTKNIDEKTIFLTGLITLLPKYPAQLLQKKFXX 378
++ E + +F I L FL+ P K EK F+ L L +P ++ +K
Sbjct: 306 A-SMFELERSPYFTGSAIAALRFLESFPEKLPSEKVSFMESLSKNLTTFPYRIQSQKILP 364
Query: 379 XXXXXXXXXCSMKETADECLQINL-EVILLIGKNLSQLSFTEKITNHI---IGSANGKVI 434
+ D+ L +L I I K L F+ K+ I I +AN
Sbjct: 365 TL---------LDHLNDQKLVPSLLPCIFEISKGLDSSIFSSKVFTAIFPIISAANSYP- 414
Query: 435 LEHGASGLIKHLSILQIKLKKDAFDKSLLKPLYEYTCESQENPNIQESLLNQLPIALETF 494
E + +++ L+ KL F ++ + Y C + N+Q + + L L+
Sbjct: 415 -ERVPLCIFQYMDCLKSKLPSGEFLSKIVP--FIYGCFENSSLNVQTTSIQILGTLLDII 471
Query: 495 DFATVKNFLSPLIQKLFTKTTSLTVKNACISCFQTMIQSNAMDTYMIQETLFPLIKSMKS 554
D TVK+ + P + F+ T L VK A + F I +D++ I + L P+++ +K+
Sbjct: 472 DVTTVKSSICPKLYHSFSVTNQLDVKVAILDTFNVFINQKFLDSFAIVDKLLPVLEKVKT 531
Query: 555 RDSRILMKFLEFFPHLYTAIQDKEELITESFIPLMFAFSMAPTLXXXXXXXXXXXXXXXX 614
R+ ++M + + I EE + E IP ++ S++P+L
Sbjct: 532 REPTVVMGMVTVYISAGAII--PEETVHEQVIPRLWILSVSPSLSLEQYNKCMREIRSLS 589
Query: 615 XQIQKRHVQQLKTEQSKSQELESKDFTKIIDTPIVPARTDTDNEISRSINVPVIKPKASP 674
+QK H ++L+++ S +VP R TD S++ SP
Sbjct: 590 DAVQKSHAKKLQSKPSS----------------VVPNRITTDPFSSQTKEATSKPSSISP 633
Query: 675 SYQATGI 681
+ T I
Sbjct: 634 NKATTNI 640
>7301728 [T] KOG2137 Protein kinase
Length = 835
Score = 129 bits (325), Expect = 1e-29
Identities = 140/635 (22%), Positives = 258/635 (40%), Gaps = 80/635 (12%)
Query: 26 WSVYTGKPKXXXXXXXGGPIDKVSVFIFDKKQFESYLLHYGIIKSKNSSHDKLFLNDAYT 85
W VY G K +VSVF+F+KK E + SK+ L
Sbjct: 46 WKVYNGHKKSTK--------QEVSVFVFEKKSLERW--------SKDDRETML------E 83
Query: 86 VLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEEL 145
LR V L K +HP++L + PLEE + F TE V SL N+ G+ +
Sbjct: 84 TLRRGVQQLTKIRHPHVLTVQHPLEESRDSLAFATEPVFASLANVV----------GDNV 133
Query: 146 LQSNDTNNLTIQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLI-K 204
++ I+ G+LQ+ L F+H VH +I ++ +N+N WKL G I
Sbjct: 134 RSEKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGFDFCIAN 193
Query: 205 LPEGTNVGDFTIPQYDPRVPTFLQIDLNFAAPELVMEDTFSARSDXXXXXXXXXXXXXXX 264
P + +Y + Q L + APEL + + SD
Sbjct: 194 QPATDGTPHWPFREYTTSLHVLAQPSLEYTAPELALNSVNTPDSDLFSLGVLIFTIYAGK 253
Query: 265 XXFLCENSKQSYRDQFTKF-ERKIASLSWDAVFQKVPQTLRFCLPRLMNRDIYSRYDNIV 323
+ + S+R +RK ++ VP L L L++ R +
Sbjct: 254 PLKMFGSDYSSFRRYANDLNQRKYPPMN------AVPSELTESLKALLHPSANLR-PKLH 306
Query: 324 EFLDNDFFKDPLIQTLIFLDDLPTKNIDEKTIFLTGLITLLPKYPAQLLQKKFXXXXXXX 383
E +F+D ++TL +LD L + +K+ F GL ++P P ++
Sbjct: 307 ELKQIAYFQDVGVKTLSYLDSLYQWDNLQKSKFYKGLPQIIPTLPHRV---------NLH 357
Query: 384 XXXXCSMKETADE-CLQINLEVILLIGKNLSQLSFTEKITNHIIGSANGKVILEHGASGL 442
+KE + + L +LLI + SQ + + I H+ K I + L
Sbjct: 358 SILPYLVKEFVNSPMIPFVLPNVLLIAEMSSQREYCDHILPHL------KPIFK-----L 406
Query: 443 IKHLSILQIKLKK----------DAFDKSLLKPLY-EYTCESQENPNIQESLLNQLPIAL 491
+ IL I ++K + +S+L LY C+ P IQ+ L LP
Sbjct: 407 TDPIQILLIFMQKMDLLLKLTPAEEVKQSVLPLLYRSLECDM---PQIQDLCLAVLPTFS 463
Query: 492 ETFDFATVKNFLSPLIQKLFTKTTSLTVKNACISCFQTMIQSNAMDTYMIQETLFPLIKS 551
D+ +KN + P I+KL ++++++VK C+ ++++ +D +++ + + P ++
Sbjct: 464 TLIDYNAMKNSVLPRIKKLCLQSSNVSVKVNCLISIGKLLEN--LDKWLVLDEILPFLQQ 521
Query: 552 MKSRDSRILMKFLEFF--PHLYTAIQDKEELITESFIPLMFAFSMAPTLXXXXXXXXXXX 609
++SR+ I+M + + T + ++++ IP + S+ L
Sbjct: 522 IQSREPAIIMGIIGIYKIAMTNTKLGITKDVMAHKCIPYLVPLSVENGLTIAQFNTIISL 581
Query: 610 XXXXXXQIQKRHVQQLKTEQSKSQELESKDFTKII 644
++++ ++L+ + ++ + KD ++I+
Sbjct: 582 IKEMMGRVEQEQREKLQQLSTIQRDNKPKDASEIL 616
>At1g71410 [T] KOG2137 Protein kinase
Length = 909
Score = 114 bits (284), Expect = 7e-25
Identities = 115/519 (22%), Positives = 221/519 (42%), Gaps = 49/519 (9%)
Query: 26 WSVYTGKPKXXXXXXXGGPIDKVSVFIFDKKQFESYLLHYGIIKSKNSSHDKLFLNDAYT 85
W +Y K + V V++ DK+ + + K+ + FL+
Sbjct: 54 WKLYAAKARDSTRPQQ---YPTVCVWMLDKRALSEARVRANLSKAAEDA----FLD---- 102
Query: 86 VLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEEL 145
++R L + +HP ++ +++ L+E+ VTE + S+ N ++V + +
Sbjct: 103 LIRADAGKLVRLRHPGVVHVVQALDENKNAMALVTEPLFASVANALGNVENVGNVPKD-- 160
Query: 146 LQSNDTNNLTIQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLIKL 205
L+S + + L ++ G+LQ+ + L+F+HN + +H I P +V + WKL+G G I
Sbjct: 161 LKSMEMSLLEVKHGLLQISETLNFLHNNANLIHRAISPENVLITSAGSWKLAGFGFAISA 220
Query: 206 PEGTNVGD---FTIPQYDPRVPTF-LQIDLNFAAPELVMEDTFS--ARSDXXXXXXXXXX 259
+ N+ + F +YD +Q LN+ APEL+ + S A SD
Sbjct: 221 AQAGNLDNMQSFHYSEYDVEDSILPVQPSLNYTAPELMRSKSPSAGASSDIFSFGCLAYH 280
Query: 260 XXXXXXXFLCENSKQSYRDQFTKFERKIASLSWDAVFQKVPQTLRFCLPRLMNRDIYSRY 319
F C N+ + Y + + F +P L L R+++ + R
Sbjct: 281 LVARKPLFDCNNNVKMYMNTLNYITNE--------SFSSIPSELVSDLQRMLSTNESFR- 331
Query: 320 DNIVEFLDNDFFK-DPLIQTLIFLDDLPTKNIDEKTIFLTGLITLLPKYPAQLLQKKFXX 378
++F ++FF+ D ++ L FLD L ++ +K+ FL L + + +++L+ K
Sbjct: 332 PTALDFTGSNFFRSDARLRALRFLDHLLERDNMQKSEFLKALSDMWKDFDSRVLRYK--- 388
Query: 379 XXXXXXXXXCSMKETADECLQ-INLEVILLIGKNLSQLSF---TEKITNHIIGSANGKVI 434
C+ E + LQ I L ++L I ++ + F T ++ +A+G +
Sbjct: 389 ----VLPPLCA--ELRNLVLQPIILPMVLTIAQSQDRTDFELITLPALVPVLSTASGDTL 442
Query: 435 LEHGASGLIKHLSILQIKLKKDAFDKSLLKPLYEYTCESQENPNIQESLLNQLPIALETF 494
L L+KH ++ K + +L L + + IQE +L + +
Sbjct: 443 LL-----LVKHADLITNKTDSEHLVSHVLPLLLR--AYNDNDVRIQEEVLKRSTSVAKQL 495
Query: 495 DFATVKNFLSPLIQKLFTKTTSLTVKNACISCFQTMIQS 533
D V+ + P + L KTT V+ + C ++Q+
Sbjct: 496 DGQVVRQAILPRVHGLALKTTVAAVRVNALLCLAELVQT 534
>At1g22870 [T] KOG2137 Protein kinase
Length = 811
Score = 76.6 bits (187), Expect = 1e-13
Identities = 44/186 (23%), Positives = 88/186 (46%), Gaps = 13/186 (6%)
Query: 26 WSVYTGKPKXXXXXXXGGPIDKVSVFIFDKKQFESYLLHYGIIKSKNSSHDKLFLNDAYT 85
W +Y+ K + V V++ DK+ G+ K+ + FL+
Sbjct: 54 WKLYSAKARDSTRPQQ---YPTVCVWVLDKRALSEARARAGLSKAAEDA----FLD---- 102
Query: 86 VLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEEL 145
++R L + +HP ++ +++ L+E+ VTE + S+ N ++V + +
Sbjct: 103 LIRADSGKLVRLRHPGVVHVVQALDENKNAMAMVTEPLFASVANALGNVENVDNVPKD-- 160
Query: 146 LQSNDTNNLTIQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLIKL 205
L+S + + L ++ G+LQ+ + L+F+HN +H + P +VF+ WKL+G G I
Sbjct: 161 LKSMEMSLLEVKHGLLQIAETLNFLHNNAHLIHRAVSPENVFITSAGSWKLAGFGFAISQ 220
Query: 206 PEGTNV 211
+ N+
Sbjct: 221 AQDGNL 226
>7294852 [T] KOG2137 Protein kinase
Length = 621
Score = 76.3 bits (186), Expect = 2e-13
Identities = 66/295 (22%), Positives = 116/295 (38%), Gaps = 43/295 (14%)
Query: 49 SVFIFDKKQFESYLLHYGIIKSKNSSHDKLFLNDAYTVLRNQVNNLAKFKHPNILQLIEP 108
SVFIF+KK E H +L++ V L +F+HP ILQ+
Sbjct: 332 SVFIFEKKIAEKL-------------HKPRRKETITELLKSSVKTLERFRHPRILQIYHT 378
Query: 109 LEEHSKNFLFVTEYVSGSLFNLFQEQDSVT----------------------STFGEELL 146
+EE + F +E + SL N+ +S T +T +
Sbjct: 379 VEESADTLAFASEPIFASLSNVLAFHESKTYEATNVAPAAGGAAASQAQAAANTLPQRPA 438
Query: 147 QSNDTN--NLTIQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLIK 204
+ + N ++ ++ G LQ+ +AL ++H +H ++ P S+ + + WKL+G+ ++ +
Sbjct: 439 HAKEYNFLDMELKYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLAGMEYVER 498
Query: 205 LPEGTNVGDFTIPQYDPRVPTFLQIDLNFAAPELVMEDTFSARSDXXXXXXXXXXXXXXX 264
+ E P + RV Q +L+F APE S SD
Sbjct: 499 MNENDLNSSIPCPPWSNRVSKMAQPNLDFMAPETQSTSKCSLLSDMFSLGMVICAVFNNG 558
Query: 265 XXFL-CENSKQSYRDQFTKFERKIASLSWDAVFQKVPQTLRFCLPRLMNRDIYSR 318
+ NS +Y Q + + L ++P L+ R+ +RD +R
Sbjct: 559 RPLIQAGNSTSNYAKQMETLDDLVHKL-----MPRLPIALQEATSRMASRDATAR 608
>CE27789 [T] KOG2137 Protein kinase
Length = 789
Score = 67.8 bits (164), Expect = 6e-11
Identities = 48/189 (25%), Positives = 80/189 (41%), Gaps = 28/189 (14%)
Query: 49 SVFIFDKKQFESYLLHYGIIKSKNSSHDKLFLNDAYTVLRNQVNNLAKFKHPNILQLIEP 108
SV +FDKK G KSK S + +++ + L HP IL +
Sbjct: 55 SVLVFDKKSNVKAPPKLG--KSKTYS--------MFDLIKYETQQLMGLIHPRILHMEHS 104
Query: 109 LEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEELLQSNDTNNLTIQRGILQVCQALD 168
LEE F TE + G+L N+ ++ + L I+ G+LQ+ +
Sbjct: 105 LEETKDYISFATEQIFGNLENVVTDES---------------LDRLEIKLGVLQIIDGMS 149
Query: 169 FIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLIKLPEGTNVGDFTIPQYDPRVPTFLQ 228
++HN +H ++ P +++V WK+ G + E + + ++P LQ
Sbjct: 150 YLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKE---PNCYPCYPWTKKLPPCLQ 206
Query: 229 IDLNFAAPE 237
DL+F APE
Sbjct: 207 PDLDFLAPE 215
>7301824 [R] KOG1243 Protein kinase
Length = 873
Score = 63.2 bits (152), Expect = 1e-09
Identities = 78/350 (22%), Positives = 136/350 (38%), Gaps = 67/350 (19%)
Query: 26 WSVYTGKPKXXXXXXXGGPIDKVSVFIFDKKQFESYLLHYGIIKSKNSSHDKLFLNDAYT 85
W+++ K K +++VSVF++D I+S + + +L
Sbjct: 30 WTLHKAKRKTT--------LEEVSVFVYD-------------IRSGSDTKCEL------- 61
Query: 86 VLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEEL 145
+ + L +HP+ILQ ++ LE K TE V T+ +L
Sbjct: 62 -AKAALKRLKTLRHPSILQYLDSLET-DKMLYVATEAVDP------------LGTYFSKL 107
Query: 146 LQSNDTNNLTIQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLIKL 205
N L + GI Q+ +AL F++N + H ++ SVFVN + +WKL L + +
Sbjct: 108 GSDNVQKGLYLAWGIFQITRALSFLNNDGNLRHNNVSAWSVFVNASGEWKLGSLEY-VSA 166
Query: 206 PEGTNVGDFTIPQYDPRVPTFLQIDLNFAAPELVMEDTFSARSDXXXXXXXXXXXXXXXX 265
+G P ++P L++ + +PE D ++
Sbjct: 167 ADGN-------PMPPAKIPVTLEV---YDSPE--KNDPSKLKAATKCSVDMWGLGCLVWE 214
Query: 266 XFLCENSKQSYRDQFTKFERKIASLSWDAVFQKVPQTLRFCLPRLMNRDIYSRYDNIVEF 325
F ++S + + SL + V R DI +R
Sbjct: 215 AFNGVLKQRSNLKDIEHIPKSLQSLYCELVGASPSN-------RPNPADIITRCRK---- 263
Query: 326 LDNDFFKDPLIQTLIFLDDLPTKNIDEKTIFLTGLITLLPKYPAQLLQKK 375
FFK+ L+ TL+FL+++ K+ EK F +GL T L +P + + K
Sbjct: 264 -PGGFFKNDLVDTLLFLEEIQIKDKAEKNRFFSGLTTHLDNFPDNVCRHK 312
>Hs8922218 [T] KOG2137 Protein kinase
Length = 332
Score = 62.0 bits (149), Expect = 3e-09
Identities = 75/345 (21%), Positives = 140/345 (39%), Gaps = 39/345 (11%)
Query: 177 VHLDIQPRSVFVNENADWKLSGLGHLIKLPEGTNVGD----FTIPQYDPRVPTFLQIDLN 232
VH +I P ++ +N++ WK+ G + TN + F ++DP +P+ +
Sbjct: 2 VHGNITPENIILNKSGAWKIMGFDFCVS---STNPSEQEPKFPCKEWDPNLPSLCLPNPE 58
Query: 233 FAAPELVMEDTFSARSDXXXXXXXXXXXXXXXXXFLCENSKQSYRDQFTKFERKIASLS- 291
+ APE ++ + SD N + Y+ F R++ LS
Sbjct: 59 YLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKS----FSRQLDQLSR 114
Query: 292 -WDAVFQKVPQTLRFCLPRLMNRDIYSRYDNIVEFLDNDFFKDPLIQTLIFLDDLPTKNI 350
+ +P+ +R + L+N R D + FF D TL + D L ++
Sbjct: 115 LGSSSLTNIPEEVREHVKLLLNVTPTVRPD-ADQMTKIPFFDDVGAVTLQYFDTLFQRDN 173
Query: 351 DEKTIFLTGLITLLPKYPAQLLQKKFXXXXXXXXXXXCSMKETAD-ECLQINLEVILLIG 409
+K+ F GL +LPK P +++ ++ C E + + + L +LLI
Sbjct: 174 LQKSQFFKGLPKVLPKLPKRVIVQRI---------LPCLTSEFVNPDMVPFVLPNVLLIA 224
Query: 410 KNLSQLSFTEKITNHIIGSANGKVILEHGASGL----IKHLSILQIKLKKDAFDKSLLKP 465
+ ++ + + I + G V + + ++ + +L K D S+L
Sbjct: 225 EECTKEEYVKLILPEL-----GPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPM 279
Query: 466 LYEYTCESQENPN--IQESLLNQLPIALETFDFATVKNFLSPLIQ 508
+Y + E P+ IQE LN +P D+ ++KN L P I+
Sbjct: 280 VY----RALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIK 320
>At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 438
Score = 53.1 bits (126), Expect = 2e-06
Identities = 44/148 (29%), Positives = 74/148 (49%), Gaps = 25/148 (16%)
Query: 74 SHDKLFLNDAYTVLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYV-SGSLFNLFQ 132
S D+L + D R++V+ L K +HPNI+Q + + E K + +TEY+ G L +
Sbjct: 196 SDDRLVIQD----FRHEVDLLVKLRHPNIVQFLGAVTER-KPLMLITEYLRGGDLHQYLK 250
Query: 133 EQDSVTSTFGEELLQSNDTNNLTIQRGILQVCQALDFIHNKTS-SVHLDIQPRSV-FVNE 190
E+ +T T T L + + + ++HN+ + +H D++PR+V VN
Sbjct: 251 EKGGLTPT--------------TAVNFALDIARGMTYLHNEPNVIIHRDLKPRNVLLVNS 296
Query: 191 NAD-WKLS--GLGHLIKLPEGTNVGDFT 215
+AD K+ GL LIK+ +V T
Sbjct: 297 SADHLKVGDFGLSKLIKVQNSHDVYKMT 324
>YGR052w [T] KOG0583 Serine/threonine protein kinase
Length = 369
Score = 52.0 bits (123), Expect = 3e-06
Identities = 38/127 (29%), Positives = 61/127 (47%), Gaps = 12/127 (9%)
Query: 99 HPNILQLIEPLEEHSKNFLFVTEYVS-GSLFNLFQEQDSVTSTFGEELLQSNDTNNLTIQ 157
HPNI +++ + S ++ V EY G L++ S S L+Q + +Q
Sbjct: 59 HPNICSMLDFYTDDSY-YIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQ------IDMQ 111
Query: 158 RGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLIKLPEGTNVGDFTIP 217
+ I Q+C A+ F H+ H DI+P ++ + N D KL+ GH I+ P+ DF I
Sbjct: 112 KIIKQLCSAISFAHS-LGIAHRDIKPENILLTINGDIKLADWGHAIQSPKS---NDFQIG 167
Query: 218 QYDPRVP 224
+ R P
Sbjct: 168 TDNYRAP 174
>SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 722
Score = 51.6 bits (122), Expect = 4e-06
Identities = 58/197 (29%), Positives = 87/197 (43%), Gaps = 33/197 (16%)
Query: 63 LHYGIIKSKNSSHDKLFLNDAYTVLRNQVNNLAKFKHPNILQLI-EPLEEHSKNFLFVTE 121
+H+G I + +K ++ D +LRN KHPNI+Q E L ++ E
Sbjct: 35 IHFGNI----TRQEKQYIADEVNILRN-------LKHPNIVQYCGEELNRSAQVINLYME 83
Query: 122 YVS-GSLFNLFQEQDSVTSTFGE-ELLQSNDTNNLTIQR----GILQVCQAL---DFIHN 172
Y G L NL Q F E E+L+ L + R C + + H
Sbjct: 84 YCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGENAPACDSQWPREIFHP 143
Query: 173 KTSSVHLDIQPRSVFVNENADWKLSGLGHLIKLPEGTNVGDFTIPQYDPRVPTFLQIDLN 232
K S +H DI+P ++F++EN KL G L KL + T V FT Q P ++
Sbjct: 144 KQSVLHRDIKPANIFLDENNSVKLGDFG-LSKLLDNTRV--FT--QSYVGTPYYM----- 193
Query: 233 FAAPELVMEDTFSARSD 249
+PE++ +SA+SD
Sbjct: 194 --SPEIIRSSPYSAKSD 208
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 51.6 bits (122), Expect = 4e-06
Identities = 68/316 (21%), Positives = 120/316 (37%), Gaps = 62/316 (19%)
Query: 86 VLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEEL 145
++ N+V+ L + KHPNI+ L+E +E ++ FL + G LF+ T G +
Sbjct: 258 LIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAM 317
Query: 146 LQSNDTNNLTIQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLS------GL 199
+ + AL ++H S VH DI+P ++ V E D S GL
Sbjct: 318 --------------VYNLANALRYLHG-LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGL 362
Query: 200 GHLIKLPEGTNVGDFTIPQYDPRVPTFLQIDLNFAAPELVMEDTFSARSDXXXXXXXXXX 259
+++ P T G PT++ APE++ E + + D
Sbjct: 363 ATVVEGPLYTVCG----------TPTYV-------APEIIAETGYGLKVDIWAAGVITYI 405
Query: 260 XXXXXXXFLCENS-KQSYRDQFTKFERKIASLSWDAVFQKVPQTL----------RFCLP 308
F EN+ ++ DQ + + + WD + + + R
Sbjct: 406 LLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAG 465
Query: 309 RLMNR----DIYSRYDN--------IVEFLDNDFFKDPLIQTLIFLDDLPTKNIDEKTIF 356
++++ D S+ +N + + +N K T + + +P K K F
Sbjct: 466 QILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSV-IMPAKQAPGKLYF 524
Query: 357 LTGLITLLPKYPAQLL 372
T +T LP +P Q L
Sbjct: 525 QTSQLTTLPAFPDQQL 540
>At4g10390 [T] KOG1187 Serine/threonine protein kinase
Length = 342
Score = 50.8 bits (120), Expect = 8e-06
Identities = 38/123 (30%), Positives = 63/123 (50%), Gaps = 21/123 (17%)
Query: 84 YTVLRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYV-SGSLFNLFQEQDSVTSTFG 142
Y V R +++ L + +HPNI++L+ ++ +N + EY+ G+L
Sbjct: 78 YQVFRLELDILLRLQHPNIVKLLGYFDDSEENGALLLEYLPQGNL--------------- 122
Query: 143 EELLQSNDTNNLTIQRGI---LQVCQALDFIHNKTSS--VHLDIQPRSVFVNENADWKLS 197
+E LQSN L + + LQ+ QA++ IH K S VH DI+ +V +++N D KL
Sbjct: 123 QEKLQSNSKQVLQWRNRVAIALQLVQAIEHIHEKCSPQIVHGDIKSSNVLLDKNFDCKLC 182
Query: 198 GLG 200
G
Sbjct: 183 DFG 185
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 50.8 bits (120), Expect = 8e-06
Identities = 37/163 (22%), Positives = 72/163 (43%), Gaps = 28/163 (17%)
Query: 87 LRNQVNNLAKFKHPNILQLIEPLEEHSKNFLFVTEYVSGSLFNLFQEQDSVTSTFGEELL 146
LR ++ L K KH NI+++++ E+++ F VTE+ G LF + ++ +
Sbjct: 50 LRQEIEILRKLKHENIIEMLDSF-ENAREFCVVTEFAQGELFEILEDDKCLPEE------ 102
Query: 147 QSNDTNNLTIQRGILQVCQALDFIHNKTSSVHLDIQPRSVFVNENADWKLSGLGHLIKLP 206
+Q Q+ +ALD++H+ +H D++P+++ + + KL G +
Sbjct: 103 --------QVQAIAKQLVKALDYLHS-NRIIHRDMKPQNILIGAGSVVKLCDFGFARAMS 153
Query: 207 EGTNVGDFTIPQYDPRVPTFLQIDLNFAAPELVMEDTFSARSD 249
T + + P ++ APELV E + D
Sbjct: 154 TNT-----VVLRSIKGTPLYM-------APELVKEQPYDRTVD 184
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,027,430
Number of Sequences: 60738
Number of extensions: 1641813
Number of successful extensions: 5490
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 5449
Number of HSP's gapped (non-prelim): 21
length of query: 767
length of database: 30,389,216
effective HSP length: 114
effective length of query: 653
effective length of database: 23,465,084
effective search space: 15322699852
effective search space used: 15322699852
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)