ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5005 normal R KOG0118 General function prediction only FOG: RRM domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5005 1713099 1715315 739
(739 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL190c [R] KOG0118 FOG: RRM domain 405 e-112
SPAC3H8.09c [R] KOG0118 FOG: RRM domain 89 3e-17
Hs4758544 [R] KOG0118 FOG: RRM domain 54 1e-06
Hs14110428 [R] KOG0118 FOG: RRM domain 54 1e-06
Hs20127499 [A] KOG0106 Alternative splicing factor SRp55/B52/SRp... 50 1e-05
Hs18545341 [R] KOG0118 FOG: RRM domain 50 1e-05
CE03763 [A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 ... 50 1e-05
>YPL190c [R] KOG0118 FOG: RRM domain
Length = 802
Score = 405 bits (1040), Expect = e-112
Identities = 202/365 (55%), Positives = 260/365 (70%), Gaps = 17/365 (4%)
Query: 147 KLTNDIESEEKQLPGESDNIDKALLEKQFKLIKEACILQNPSFKNASEQEQISALIAILN 206
K+T + E++ P +N++ LL+KQ K I ++ +L P F++ ++E++SA++A+LN
Sbjct: 188 KITRE-ENDNTHFPTNMENVNYDLLQKQVKYIMDSNMLNLPQFQHLPQEEKMSAILAMLN 246
Query: 207 SDPQTAM---PHXXXXXXXXXXXXXXXKGKN-------------VRFPRPNMSQPMSAEE 250
S+ TA+ PH N +RFPR ++S+P++ EE
Sbjct: 247 SNSDTALSVPPHDSTISTTASASATSGARSNDQRKPPLSDAQRRMRFPRADLSKPITEEE 306
Query: 251 KERYSEYLNGETKITEIQSFPPKSRLFIGNLPLKNVTKEDLFRIFSPYGHIFQINIKNAF 310
+RY+ YL+GE KITE+ + PPKSRLFIGNLPLKNV+KEDLFRIFSPYGHI QINIKNAF
Sbjct: 307 HDRYAAYLHGENKITEMHNIPPKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKNAF 366
Query: 311 GFIQYDNQRSVLDAIECESEEMNFGKKLILEVSSSNARPQFDHGDHGSNTSSTYVTSSKR 370
GFIQ+DN +SV DAIECES+EMNFGKKLILEVSSSNARPQFDHGDHG+N+SST+++S+KR
Sbjct: 367 GFIQFDNPQSVRDAIECESQEMNFGKKLILEVSSSNARPQFDHGDHGTNSSSTFISSAKR 426
Query: 371 XXXXXXXXXXXXXXXXHYKKSKKRTPQCLIYVKKAADRTYAYSVFTNLSKKTGLETDMVI 430
YKKS++ T C I+VK+ ADRTYA VF TGLETDM+
Sbjct: 427 PFQTESGDMYNDDNGAGYKKSRRHTVSCNIFVKRTADRTYAIEVFNRFRDGTGLETDMIF 486
Query: 431 LKPRMELRKLVNEAAYDGVWGVVLVNKNKNIDVQTFYLGPSGETKSDEYVAVSIDEAISI 490
LKPRMEL KL+N+AAY+GVWGVVLVNK N+DVQTFY G GETK DEY+++S D+A++I
Sbjct: 487 LKPRMELGKLINDAAYNGVWGVVLVNKTHNVDVQTFYKGSQGETKFDEYISISADDAVAI 546
Query: 491 FNNIK 495
FNNIK
Sbjct: 547 FNNIK 551
>SPAC3H8.09c [R] KOG0118 FOG: RRM domain
Length = 738
Score = 88.6 bits (218), Expect = 3e-17
Identities = 74/285 (25%), Positives = 126/285 (43%), Gaps = 23/285 (8%)
Query: 243 SQPMSAEEKERYSEYLNGETKITEIQ---SFPPKSRLFIGNLPLKNVTKEDLFRIFSPYG 299
S M+ E+++R+ ++L E I FP SRLF+G+L K+++K +L+++F YG
Sbjct: 329 SLQMNLEDEQRFQQFLKDEESIMSNWYPGQFPSASRLFLGHLNTKSLSKRNLWKVFKIYG 388
Query: 300 HIFQINIKNAFGFIQYDNQRSVLDAIECESEEMNFGKKLILEVS--SSNARPQFDHGDHG 357
+ QI +K +GF+Q+ A+ E G+KL LE+S + Q ++ G
Sbjct: 389 PLAQIVLKANYGFVQFFTNEDCARALNAEQGNFVRGQKLHLEISKIQKKYQNQIENMKKG 448
Query: 358 SNTSST-----------YVTSS-KRXXXXXXXXXXXXXXXXHYKKSKKRTPQCLIYVKKA 405
S+ + + Y TSS KR SK +P C I V +
Sbjct: 449 SHVTKSNQYSEMIGNLPYPTSSRKRTRSPLMSKGKSYDRKGSISMSKNFSPDCEILVTED 508
Query: 406 ADRTYAYSVFTNLSKKTGLETDMVILKPRMELRKLVNEAAYDGVWGVVLVNKN----KNI 461
+ + + V + ++ L L L+ ++ + V ++L+N +
Sbjct: 509 CPKEFVWGV-EKVFQERRLNIHTTCLYRDSNLQVIIKSCIINSVKSIILINAGLAHLGKV 567
Query: 462 DVQTFYLGPS-GETKSDEYVAVSIDEAISIFNNIKATKIGLPARS 505
VQ F G S E + DEY AV + A SI ++ K + + A S
Sbjct: 568 SVQVFKDGSSDSEVRCDEYAAVDVMVAASIVHHAKTSLMHSAASS 612
>Hs4758544 [R] KOG0118 FOG: RRM domain
Length = 290
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/95 (34%), Positives = 49/95 (50%), Gaps = 3/95 (3%)
Query: 274 SRLFIGNLPLKNVTKEDLFRIFSPYGHIFQINIKNAFGFIQYDNQRSVLDAIECESEEMN 333
SR+FIGNL V K D+ IFS YG I ++ F F+QY N+R+ A+ E M
Sbjct: 16 SRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMI 75
Query: 334 FGKKLILEVSSSNARPQFDHGDHGSNTSSTYVTSS 368
G+ L + ++ A P+ + G G S+ + S
Sbjct: 76 AGQVLDINLA---AEPKVNRGKAGVKRSAAEMYGS 107
>Hs14110428 [R] KOG0118 FOG: RRM domain
Length = 303
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/95 (34%), Positives = 49/95 (50%), Gaps = 3/95 (3%)
Query: 274 SRLFIGNLPLKNVTKEDLFRIFSPYGHIFQINIKNAFGFIQYDNQRSVLDAIECESEEMN 333
SR+FIGNL V K D+ IFS YG I ++ F F+QY N+R+ A+ E M
Sbjct: 16 SRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMI 75
Query: 334 FGKKLILEVSSSNARPQFDHGDHGSNTSSTYVTSS 368
G+ L + ++ A P+ + G G S+ + S
Sbjct: 76 AGQVLDINLA---AEPKVNRGKAGVKRSAAEMYGS 107
>Hs20127499 [A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM
superfamily)
Length = 344
Score = 50.4 bits (119), Expect = 1e-05
Identities = 28/87 (32%), Positives = 55/87 (63%), Gaps = 4/87 (4%)
Query: 275 RLFIGNLPLKNVTKEDLFRIFSPYGHIFQINIKNAFGFIQYDNQRSVLDAI-ECESEEMN 333
R++IG L NV ++D+ R FS YG + ++++KN +GF+++++ R DA+ E +E+
Sbjct: 3 RVYIGRLSY-NVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL- 60
Query: 334 FGKKLILEVSSSNARPQFDHGDHGSNT 360
G+++I+E + R + D +GS +
Sbjct: 61 CGERVIVEHARGPRRDR-DGYSYGSRS 86
>Hs18545341 [R] KOG0118 FOG: RRM domain
Length = 293
Score = 50.4 bits (119), Expect = 1e-05
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 274 SRLFIGNLPLKNVTKEDLFRIFSPYGHIFQINIKNAFGFIQYDNQRSVLDAIECESEEMN 333
SR+FIGNL V K D+ IFS YG I ++ F F+QYD +++ A+ E M
Sbjct: 16 SRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMI 75
Query: 334 FGKKLILEVSSSNARPQFDHGDHGSNTSSTYVTSS 368
+ + + ++ A P+ + G+ G S+ + S
Sbjct: 76 ASQVVDINLA---AEPKVNRGNAGVKRSAAEMYGS 107
>CE03763 [A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM
superfamily)
Length = 312
Score = 50.4 bits (119), Expect = 1e-05
Identities = 27/84 (32%), Positives = 51/84 (60%), Gaps = 5/84 (5%)
Query: 274 SRLFIGNLPLKNVTKEDLFRIFSPYGHIFQINIKNAFGFIQYDNQRSVLDAIECESEEMN 333
+R++IG L + V+++D+ F YG I + +KN FGF+++D++R DA+ + +
Sbjct: 3 ARIYIGRLTSR-VSEKDIEHFFRGYGQIRDVLLKNGFGFVEFDDKRDAEDAVHDLNGKEL 61
Query: 334 FGKKLILEVSSSNARPQFDHGDHG 357
G+++IL+ S +P+ GD G
Sbjct: 62 GGERVILDYS----KPRGGGGDRG 81
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.309 0.129 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,218,985
Number of Sequences: 60738
Number of extensions: 1075151
Number of successful extensions: 2357
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2352
Number of HSP's gapped (non-prelim): 8
length of query: 739
length of database: 30,389,216
effective HSP length: 114
effective length of query: 625
effective length of database: 23,465,084
effective search space: 14665677500
effective search space used: 14665677500
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)