ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5046 check: MH U KOG1059 Intracellular trafficking, secretion, and vesicular transport Vesicle coat complex AP-3, delta subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5046 1728676 1725953 -908
(908 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL195w [U] KOG1059 Vesicle coat complex AP-3 delta subunit 815 0.0
SPAC144.06 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 361 2e-99
Hs20127438 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 339 1e-92
7292917 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 332 2e-90
CE24044 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 325 1e-88
At1g48760 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 259 2e-68
SPCP1E11.06 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 140 9e-33
At1g60070 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 137 1e-31
At1g23900 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 132 2e-30
At1g31730 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 131 4e-30
CE25176 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 127 8e-29
7291008 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 124 5e-28
Hs6671551 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 122 2e-27
At5g22780 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 120 1e-26
At5g22770 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 120 1e-26
Hs18104998 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 119 2e-26
SPBC691.03c [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 117 6e-26
CE28680 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 109 2e-23
Hs4503843 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 109 2e-23
7296210 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 109 2e-23
Hs19913416 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 99 3e-20
Hs19913414 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 99 3e-20
CE28513 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 92 3e-18
At4g23460 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 92 3e-18
7292916 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 91 8e-18
At4g11380 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 90 2e-17
Hs4557469 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 86 3e-16
HsM4501973 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 84 1e-15
Hs22027653 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 84 1e-15
Hs22027651 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 84 1e-15
YPR029c [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 82 4e-15
7293642 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 82 4e-15
At1g23940_3 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 70 1e-11
CE24628 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 70 1e-11
YDR238c [U] KOG1058 Vesicle coat complex COPI beta subunit 68 6e-11
7293454 [U] KOG1058 Vesicle coat complex COPI beta subunit 57 1e-07
>YPL195w [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 932
Score = 815 bits (2106), Expect = 0.0
Identities = 435/854 (50%), Positives = 569/854 (65%), Gaps = 42/854 (4%)
Query: 1 MSSIYGTSAEDVKKRLRPFGIFFEKSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVK 60
M+S+Y AED+++RLRPFG FFEKSLKDLIKGIRS+NETPE+L F Q + ECREEV
Sbjct: 1 MTSLYAPGAEDIRQRLRPFGFFFEKSLKDLIKGIRSHNETPEKLDQFFKQVLSECREEVN 60
Query: 61 SPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDI 120
SPD N KTNAVLKLTYLEMYGFDMAW NFH+LEVMSSN QQKRVGYLAASQSFYKDSDI
Sbjct: 61 SPDLNSKTNAVLKLTYLEMYGFDMAWCNFHILEVMSSNKLQQKRVGYLAASQSFYKDSDI 120
Query: 121 LMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKK 180
LMLATNLLKKDLKYD +N+ VK+G+ALSGLSTI+TP LARDI DDLF MLNS +PY+RKK
Sbjct: 121 LMLATNLLKKDLKYDGNNDVVKVGIALSGLSTIITPSLARDIADDLFTMLNSTRPYIRKK 180
Query: 181 AVTALFKVFLQYPESLRDGLSKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLL 240
A+TALFKVFLQYPE+LRD KFVS L+D+D SVVSAAVSVICEL+K NP PFIQ SPLL
Sbjct: 181 AITALFKVFLQYPEALRDNFDKFVSKLDDDDISVVSAAVSVICELSKKNPQPFIQLSPLL 240
Query: 241 YEMLIQIDNNWIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKTTAISVIYESINCIVK 300
YE+L+ IDNNWIIIRLLKLFT+LS+ EPKLR K+LPK+LELM+ T A SVIYES+NCIVK
Sbjct: 241 YEILVTIDNNWIIIRLLKLFTNLSQVEPKLRAKLLPKILELMESTVATSVIYESVNCIVK 300
Query: 301 GQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLL 360
G MLEEDD++TA CL L + S DPNLRYISC+LFY IGKIN +FI ++D+L+I LL
Sbjct: 301 GNMLEEDDFETAMACLERLHTFCDSQDPNLRYISCILFYKIGKINTDFISRFDQLIIRLL 360
Query: 361 KDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDT--------VHVNDQGVQIDI 412
DVD+SIR+K +EL GI DN+K +V+ L+KQFVD D V+ + + I I
Sbjct: 361 SDVDVSIRSKAIELVEGIVDEDNLKAIVQTLMKQFVDEDVVILQTGSIVYEKSKRIPIII 420
Query: 413 PLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRN 472
P NYK+K+ ++ +C ++Y ++N DF+WY ++ DL ++ QD+++ + + +G+ FRN
Sbjct: 421 PENYKIKMVNVIISICSADNYSSVN-DFEWYNAVIMDLAMLCQDISDKSLGSKIGEQFRN 479
Query: 473 IMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNCDTLVGILLNK 532
+M+KVPSMR+ + +IKL +ND+I +LP +L+E IWC GE+S L++N + L+ I+
Sbjct: 480 LMIKVPSMREVTIANIIKLISNDNINKQLPTVLRECIWCLGEFSTLVENGNDLIKIMTEN 539
Query: 533 ANKLPDTVIQTMIPALVKLFSTYANTEGRTKS-EISDLLSTLIAFMEQKYRSTNFDIQER 591
+ +V + +I ALVK+FS + N K EI +L LI F E S+ F++QER
Sbjct: 540 ISYYSHSVQEVLILALVKVFSNWCNNFQEDKRFEIKMVLKELIEFFENLSYSSTFEVQER 599
Query: 592 SVEFYEMLKLCQDALQDETEGLPLLITDVLPSLFNEYELGPMSHGQQQQLVKALTLDLDT 651
SVE E L+L +AL+++TEGLP+L+++VLPS FN YEL P++ G Q +L LDL+T
Sbjct: 600 SVEVLEFLRLSLEALEEDTEGLPMLLSEVLPSFFNAYELAPIARGTQLKLAVDENLDLET 659
Query: 652 PFLSSVELEELM--KNEELYEDEAAYYSDKESVKXXXXXXXXXXXVTQDISSEKDISMTX 709
PFL+ +EL+ + + D + S E V+ V +S ++
Sbjct: 660 PFLTKEAADELLDEQKSDAISDLMSDISMDEQVE--------LKFVDDSDTSYEEKEKLD 711
Query: 710 XXXXXXXXXXXXXXXDNPFYLNDDKIDRAETKLIELSDNDDEGETKTIEPVIXXXXXXXX 769
NP+YL ++ +R + L N++E K E +
Sbjct: 712 DFENPFEIEREKERMSNPYYLGEEDEERTKNSKDLLDLNEEESSDKKPETIRLNRTDNSL 771
Query: 770 XXXXXX----------------VQILSD--IVVAPPSTITKEGKKKSNTSGHS----DAI 807
VQ+LSD ++ A P K N S + D I
Sbjct: 772 NSLSLSTTEISRKKKKGKKKNRVQVLSDEPVIEAAPKRKDAFQKPHDNHSTQNPLKKDKI 831
Query: 808 TLSTSNKFKSFDFS 821
L ++ ++FDFS
Sbjct: 832 NLRMHSQLENFDFS 845
>SPAC144.06 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 834
Score = 361 bits (927), Expect = 2e-99
Identities = 226/682 (33%), Positives = 377/682 (55%), Gaps = 44/682 (6%)
Query: 23 FEKSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGF 82
FE++L DLIKGIRS+ E F+ ++ECR+E S D ++K+ A+LKL YLEM G
Sbjct: 3 FERTLIDLIKGIRSHANDEEA---FIATCLLECRKEATSQDADLKSEAILKLAYLEMLGV 59
Query: 83 DMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVK 142
D++WA+F ++EVMSS+ QK+ GYLAA QSF D+D+LML TNLLKKDL +S++ +
Sbjct: 60 DISWASFQIVEVMSSSKILQKQKGYLAAVQSFKPDTDVLMLTTNLLKKDL---MSSKVPE 116
Query: 143 MGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSK 202
+ +A+ GLS T LARD+ D+ ++LN PYVRK+ + L+++ LQYPE++ + K
Sbjct: 117 ITLAIDGLSHFSTLGLARDLYRDVLILLNHSVPYVRKRTILLLYRLCLQYPEAISACIPK 176
Query: 203 FVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWIIIRLLKLFTS 262
L+D DTSVV+AAVSVICELA+ P +++F+P L+ +L NNW++I+L+KLF S
Sbjct: 177 LRERLDDPDTSVVNAAVSVICELARRAPKNYLEFAPDLFHLLTTSSNNWMLIKLIKLFAS 236
Query: 263 LSKEEPKLRYKILPKVLELMDKTTAISVIYESINCIVKGQML--EEDDYDTAHQCLNHLE 320
L+ EP+L K++P + ++++ T A+S++YE IN IV G ML A C + L
Sbjct: 237 LTPYEPRLVKKLIPSLTDIIENTHAMSLLYECINTIVSGNMLVGHSQCDKLASLCASKLR 296
Query: 321 SLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIAS 380
+ D NL+YI+ + + + + +++ L D D SIR + L+L + I +
Sbjct: 297 GFFEDTDQNLKYIALLCLRKLANTHPSLVSAQLDIILKCLVDTDTSIRLRALDLVNEIVN 356
Query: 381 TDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDF 440
+NI+ +V+ L+ Q + V ++ V+ + + A ++++ + Y NI DF
Sbjct: 357 KENIRTIVKTLMLQLI----VSSDESAVE-----DIRNSTATRIIEMTSKSTYMNI-ADF 406
Query: 441 DWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMR--------DAALEQLIKLT 492
+W L + DL ++ ++ TLL + ++ V+V ++R A L+ T
Sbjct: 407 EWLLTVYVDLA----NIPGIDTGTLLNNQIIDLCVRVKALRPFSVDIFSQAILDPSYVST 462
Query: 493 TNDDIIAKLPNLLKEGIWCFGEYSELIDN-CDTLVGILLNKANKLPDTVIQTMIPALVKL 551
T+ + K ++L IWC GEY+E I+ D L + K + + ++ A+ K+
Sbjct: 463 TDCSVSEKRTDILPAIIWCLGEYAEFIEEYLDILDALTRPSFKKCSNLAHRLLLQAITKI 522
Query: 552 FSTYANTE----GRTKSEISDL-LSTLIAFMEQKYRSTNFDIQERSVEFYEMLKLCQDAL 606
F + E G K + L + +++F+EQ + +IQ R+ EFY + D +
Sbjct: 523 FCQWCLEEEPTWGVEKFGLVKLWVEKIVSFIEQFLNFQDMEIQRRASEFYILFNQVSDIV 582
Query: 607 --QDETEGL------PLLITDVLPSLFNEYELGPMSHGQQQQLVKALTLDLDTPFLSSVE 658
D E L P ++ + + LF L P++ Q++++ LDL+ P +E
Sbjct: 583 NTSDTMEVLELQKKPPYIVQNTMYKLFFGEPLNPVAVKAQRKVMPDENLDLNCPINGVIE 642
Query: 659 LEELMKNEELYEDEAAYYSDKE 680
+ + + + D++ D E
Sbjct: 643 VPKELLENIIQSDDSLINFDTE 664
>Hs20127438 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 1153
Score = 339 bits (869), Expect = 1e-92
Identities = 213/666 (31%), Positives = 372/666 (54%), Gaps = 46/666 (6%)
Query: 23 FEKSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGF 82
F+K+L+DL++GIR++ E + +++Q I E ++E+K + +K NAV KLTYL+M G+
Sbjct: 14 FDKNLQDLVRGIRNHKEDEAK---YISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGY 70
Query: 83 DMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVK 142
D++WA F+++EVMS++ F KR+GYLAASQSF++ +D++ML TN ++KDL +T
Sbjct: 71 DISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDT-- 128
Query: 143 MGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSK 202
GVAL+GLS VTP+LARD+ +D+ +++ KPY+RKKAV ++KVFL+YPESLR +
Sbjct: 129 -GVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPR 187
Query: 203 FVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWIIIRLLKLFTS 262
LED D V SAAV+VICELA+ NP ++ +PL ++++ NNW++I+++KLF +
Sbjct: 188 LKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGA 247
Query: 263 LSKEEPKLRYKILPKVLELMDKTTAISVIYESINCIVKGQMLEEDDYD----TAHQCLNH 318
L+ EP+L K++ + L+ T+A+S++YE +N ++ + + C+
Sbjct: 248 LTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQK 307
Query: 319 LESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGI 378
L L++ D NL+Y+ + I K + + + + L++ L D D SIR + L+L G+
Sbjct: 308 LRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGM 367
Query: 379 ASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENING 438
S KNL+ I+ K VD Y+ ++ ++D+C ++Y+ I
Sbjct: 368 VSK---KNLMEIVKKLMTHVDKAE----------GTTYRDELLTKIIDICSQSNYQYIT- 413
Query: 439 DFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDII 498
+F+WY+ IL +L L L+ ++ ++V ++R A+ Q+ L + ++
Sbjct: 414 NFEWYISILVEL----TRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLL 469
Query: 499 AK------LPNLLKEGIWCFGEYSE-LIDNCDTLVGILLNKANKLPDTVIQTMIPALVKL 551
A + +L W GE+SE L + TL +L + LP + + +VKL
Sbjct: 470 ASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKL 529
Query: 552 F-STYANTEGRTKSEISDLLSTL-IAFMEQKYRSTNFDIQERSVEFYEMLKLCQDALQDE 609
+ S E ++E + ++ L + + Q +S + ++QER+ +++K Q +
Sbjct: 530 YASILQQKEQAGEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQ-----K 584
Query: 610 TEGLPLLITDVLPSLFNEYELGPMSHGQQQQLVKALTLDLDTPF---LSSVELEELMKNE 666
+ + + + + +LF EL P++ Q+++ LDLD LS E E+
Sbjct: 585 LQAKDVPVAEEVSALF-AGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDERPRA 643
Query: 667 ELYEDE 672
+E+E
Sbjct: 644 VFHEEE 649
>7292917 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 627
Score = 332 bits (850), Expect = 2e-90
Identities = 194/614 (31%), Positives = 349/614 (56%), Gaps = 41/614 (6%)
Query: 19 FGIFFEKSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLE 78
F F+K+L DL++GIR+N + + +++ I E ++E++ + ++K NAV KLTY++
Sbjct: 11 FERMFDKNLTDLVRGIRNNKDNEAK---YISTCIEEIKQELRQDNISVKCNAVAKLTYIQ 67
Query: 79 MYGFDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSN 138
M G+D++WA F+++EVMSS+ F KR+GYLAASQ F+ DS++LML TN+++KDL S
Sbjct: 68 MLGYDISWAGFNIIEVMSSSRFTCKRIGYLAASQCFHPDSELLMLTTNMIRKDLN---SQ 124
Query: 139 ETVKMGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRD 198
GVALSGLS ++P+L+RD+ +D+ +++S KPY+R KAV ++KVFL+YPE+LR
Sbjct: 125 NQYDAGVALSGLSCFISPDLSRDLANDIMTLMSSTKPYLRMKAVLMMYKVFLRYPEALRP 184
Query: 199 GLSKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWIIIRLLK 258
K LED D V SAAV+VICELA+ NP ++ +P+ ++++ NNW++I+++K
Sbjct: 185 AFPKLKEKLEDPDPGVQSAAVNVICELARKNPKNYLPLAPIFFKLMTTSTNNWMLIKIIK 244
Query: 259 LFTSLSKEEPKLRYKILPKVLELMDKTTAISVIYESINCIVKGQMLEEDDYD----TAHQ 314
LF +L+ EP+L K++ + L+ T+A+S++YE IN ++ + +
Sbjct: 245 LFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECINTVIAVLISISSGMPNHSASIQL 304
Query: 315 CLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVDISIRTKVLEL 374
C+ L L++ D NL+Y+ + I K + + + + L++ L D D SIR + L+L
Sbjct: 305 CVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQAHKDLILACLDDKDESIRLRALDL 364
Query: 375 CSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYE 434
G+ S N+ +V+ L+ + D+ L YK V+++C + Y
Sbjct: 365 LYGMVSKKNLMEIVKRLLGHMERAEGSAYRDE-------LLYK------VIEICAQSSYL 411
Query: 435 NINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLTTN 494
+ +F+WYL +L +L + + L+ + ++ ++VP +R A+ ++ L
Sbjct: 412 YVT-NFEWYLTVLVELIQLEAGSRH---GRLIAEQLLDVAIRVPVVRQFAVNEMTNLLDT 467
Query: 495 DDIIAK---LPNLLKEGIWCFGEYSELIDNCDTLVGILLNKANKLPDTVIQTMIPALVKL 551
+ A+ + +L W GE++ +++ + + ILL + LP + + ++KL
Sbjct: 468 FTVSAQSNSMYEVLYAAAWIVGEFAGELEDAEKTLNILL-RPRLLPGHIQGVYVQNVIKL 526
Query: 552 FSTYANTEGRTKSEISDL--LSTLIAFMEQKYR----STNFDIQERSVEFYEMLKLCQDA 605
F+ A T E+ DL L TL + K + S++ ++QER+ ++++ ++
Sbjct: 527 FARLAT----TCLELQDLPGLVTLCDHVLDKLQHFNGSSDIEVQERANSACMLIEMLRNQ 582
Query: 606 LQDETEGLPLLITD 619
L T+ + + T+
Sbjct: 583 LSTSTDAMAMDTTN 596
>CE24044 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 1251
Score = 325 bits (834), Expect = 1e-88
Identities = 197/642 (30%), Positives = 359/642 (55%), Gaps = 44/642 (6%)
Query: 23 FEKSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGF 82
F+KSL DLI+GIR+N + + ++ Q + E ++E++ +K NA+ KL YL+M G+
Sbjct: 14 FDKSLTDLIRGIRNNKDNESR---YITQCMEEIKQELRQDSIYVKANAIEKLAYLQMLGY 70
Query: 83 DMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVK 142
D++WA+F+V+EVM+S + +KR+GYLAA+QSF+ ++D+LML TNL++KD+ S+ +
Sbjct: 71 DISWASFNVIEVMASTKYTEKRIGYLAAAQSFHDETDVLMLTTNLIRKDVN---SSNMYE 127
Query: 143 MGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSK 202
G+AL GLS VTP+LARD+ D+ +L+ + Y RK+AV L+K+FL+YP++LR +
Sbjct: 128 SGIALGGLSCFVTPDLARDLAADVVNLLSCSRNYTRKRAVLLLYKIFLKYPDALRPTFPR 187
Query: 203 FVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWIIIRLLKLFTS 262
LED D V S+AV+VICELA+ NP ++ +P+ ++++ NNW++I+++KLF +
Sbjct: 188 LKEKLEDPDPGVQSSAVNVICELARKNPKNYLTLAPVFFKLMTTSSNNWMLIKIIKLFGA 247
Query: 263 LSKEEPKLRYKILPKVLELMDKTTAISVIYESINCIVKG--QMLEEDDYDTAHQ-CLNHL 319
L EP+L K+L + L++ T+A+S++YE IN ++ + D+ + Q C+ L
Sbjct: 248 LVPLEPRLGKKLLEPLTNLINSTSAMSLLYECINTVIAVLISISAGGDHTASIQLCVQKL 307
Query: 320 ESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIA 379
L++ D NL+Y+ + I K + + + + +V+ L D D SIR + L+L G+
Sbjct: 308 GVLIEDSDQNLKYLGLLAMGKILKTHPKAVQAHKDIVLRCLDDKDESIRIRSLDLLYGMV 367
Query: 380 STDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGD 439
S NI +V+ L++ + H Y+ ++ ++ +C ++Y+ I +
Sbjct: 368 SKKNIVEIVKKLMEHVEAAEGSH-------------YRDELLSRIIGICSWSNYQYIT-N 413
Query: 440 FDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDII- 498
F+WY+ +L +L V E + + +++ V+V S+R ++ Q+ L N ++
Sbjct: 414 FEWYISVLVELTKV----EGTEHGAKIAEQIQDVTVRVESIRHFSVSQMALLVENAHVLL 469
Query: 499 -------AKLPNLLKEGIWCFGEYSELIDNCD-TLVGILLNKANKLPDTVIQTMIPALVK 550
+ + +L W GEYS+ + N L +L K + +P ++ + + K
Sbjct: 470 AGSAQQRSNMCEVLLAAAWICGEYSQHVRNQQGVLESMLKAKPSVMPGHILSVYVQNIGK 529
Query: 551 LF-STYANTEGRTKSEISDLLSTL-IAFMEQKYRSTNFDIQERSVEFYEMLKLCQDALQD 608
L+ S + E + D L L ++ + Q S + + QER+ ++++ + QD
Sbjct: 530 LYCSLMSQAEEEDDWDAIDSLDNLMLSKLPQFELSEHLEAQERACNLMAIIRIVEKLHQD 589
Query: 609 ETEGLPLLITDVLPSLFNEYELGPMSHGQQQQLVKALTLDLD 650
+ + + L+ + EL P++ Q+++ LDLD
Sbjct: 590 RQK-----MGSEVQKLY-DGELNPVATKAQRKVPVPDGLDLD 625
>At1g48760 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 869
Score = 259 bits (661), Expect = 2e-68
Identities = 191/693 (27%), Positives = 347/693 (49%), Gaps = 67/693 (9%)
Query: 23 FEKSLKDLIKGIRSNNETPEQL---QDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLE- 78
F++SL+DLIKG R QL +F+++A+ E R E+K+ D + K+ A+ KL+YL
Sbjct: 13 FQRSLEDLIKGFRL------QLLGESNFISRAVEEIRREIKATDLSTKSTALHKLSYLAA 66
Query: 79 MYGFDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSN 138
++G DM+WA FH +EV+SS+ FQ KR+GY A +QSF + +++L TN ++KDL S
Sbjct: 67 LHGVDMSWAAFHAVEVVSSSRFQHKRIGYQAITQSFNDQTSVMLLITNQVRKDLN---SA 123
Query: 139 ETVKMGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRD 198
++ +AL LS I T +LARD+ ++F +L S K +V+KKA+ + +VF +Y ++++
Sbjct: 124 NEYEVSLALECLSRIGTHDLARDLTPEVFTLLGSSKSFVKKKAIGVVLRVFEKYHDAVKV 183
Query: 199 GLSKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWIIIRLLK 258
+ V LE D ++SA V V CELA +P + +P Y++L+ NNW++I++LK
Sbjct: 184 CFKRLVENLETSDPQILSAVVGVFCELATKDPQSCLPLAPEFYKVLVDSRNNWVLIKVLK 243
Query: 259 LFTSLSKEEPKLRYKILPKVLELMDKTTAISVIYESINCIVKGQMLEEDDYDTAHQCLNH 318
+F L+ EP+L K+ + E M +T A S+++E + +V L +++
Sbjct: 244 IFAKLALIEPRLGKKVAEPICEHMRRTVAKSLVFECVRTVVSS--LSDNEAAVKLAVAKI 301
Query: 319 LESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGI 378
E LV+ DPNL+Y+ + + +++ ++V+ + D D +++ + L L +
Sbjct: 302 REFLVED-DPNLKYLGLNALSIVAPKHLWAVLENKEVVVKAMSDEDPNVKLEALHLLMAM 360
Query: 379 ASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENING 438
+ DN+ + RIL+ + D + N+ + +VL C N YE I
Sbjct: 361 VNEDNVSEISRILMNYALKSDPLFCNE--------------IIFSVLSACSRNAYE-IIV 405
Query: 439 DFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDII 498
DFDWYL +L ++ + ++ L D + P + + LI ++
Sbjct: 406 DFDWYLSLLGEMARIPHCQRGEDIEHQLIDIGMRVRDARPQLVRVSWALLIDPALLGNLF 465
Query: 499 AKLPNLLKEGIWCFGEYSELIDN-CDTLVGILLNKANKLPDTV----IQTMIPALVKLFS 553
L +L W GEY E N +T+ +L + + LP ++ I + LV
Sbjct: 466 --LHPILSAAAWVSGEYVEFSKNPYETVEALLQPRTDLLPPSIKAIYIHSAFKVLVFCLG 523
Query: 554 TYANTEGRTKSEISDLLST----LIAFMEQKYRST---------------NFDIQERSVE 594
+Y +++ T S ++ S+ + F + S + ++QER+
Sbjct: 524 SYFSSQEPTSSSLAQESSSGSLLVNVFTHESILSLVNVIELGLGPLSGYHDVEVQERAKN 583
Query: 595 FYEMLKLCQDALQD-----ETEGLPLLITDVLPSLFNEYELGPMSHGQQQQLVKALTLDL 649
+ + + + + + E +T + +F+E E GP+S Q+++ L+L
Sbjct: 584 VLGYISVIKQEIAEQLNLQDNETEASRVTAFMEDVFSE-EFGPISATAQEKVCVPDGLEL 642
Query: 650 DTPFLSSVELEELM-KNEELYEDEAAYYSDKES 681
+ +LEE+ ++ + E ++ Y+DK S
Sbjct: 643 KE---NLGDLEEICGEHLKPVESDSVSYTDKIS 672
>SPCP1E11.06 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 865
Score = 140 bits (353), Expect = 9e-33
Identities = 148/636 (23%), Positives = 279/636 (43%), Gaps = 91/636 (14%)
Query: 26 SLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVK--SPDFNMKTNAVLKLTYLEMYGFD 83
SLK IK +R++ T E+ L ++ + R+ ++ S D M+ V KL YL + G
Sbjct: 32 SLKSFIKAVRASKTTAEEHTTILKES-AQIRKNIRQGSNDMRMRRKNVAKLLYLFLLGEP 90
Query: 84 MAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKM 143
+ L+++SS+ F KR+GYLAA ++ ++L L TN L+ DLK S + +
Sbjct: 91 THFGQIECLKLLSSSRFMDKRLGYLAAMLLLDENQEVLTLLTNSLQNDLK---SRDKFIV 147
Query: 144 GVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKF 203
G+ALS + PELARD+ +D+ + ++ Y+ KKAV +V + P+ + K
Sbjct: 148 GLALSAFGNVAGPELARDLSNDIAELCSNHHNYISKKAVLCALRVIQKEPDLESLYIEKT 207
Query: 204 VSTLEDEDTSVVSAAVSVICELAKHNPGPFIQF----SPLLYEM-------------LIQ 246
L + V+ AA++ K NP +F L+Y + +
Sbjct: 208 DELLHSKSHGVLMAALAFAISACKINPSLISRFESQADDLIYRIRQLSTSTYSSEHNIGN 267
Query: 247 IDNNWIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKTTAI-----SVIYESINCIVKG 301
I + ++ +++L+ + L + PK+ K+ + ++ T + +++Y+++ I+
Sbjct: 268 ISDPFLQVKILQFLSILGQNNPKIYDKMSDLLAQVCTNTDSSRNAGNAILYQAVRTILD- 326
Query: 302 QMLEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLK 361
D +N L + + D N RY++ + + + ++ ++ L
Sbjct: 327 ---LNSDSSLRVLGVNILAKFLGNRDNNTRYVALNMLKLVVNSEENAVQRHRSTILACLN 383
Query: 362 DVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVA 421
DVD SI+++ LEL + + + N++ +VR L+ F+D +V+D+ + A
Sbjct: 384 DVDSSIQSRALELSTFLVNEANVRFMVRELL-SFLD----NVSDE---------LRGSTA 429
Query: 422 KTVLDVCCINDY-ENINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSM 480
+ + +V N + N FD L++ N + STL F ++ P +
Sbjct: 430 QYITEV--TNAFAPNKRWHFDTLLRVFKSAG------NFVSESTL--STFLRLIASAPEL 479
Query: 481 RDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELI-------DNCDTL-------- 525
+ A+ +L D L W GEY +++ D+ TL
Sbjct: 480 HEYAVVKLYAALKED---VSQEALTLSAFWVIGEYGQMLLSPTMNFDDDQTLPHSVSESD 536
Query: 526 ----VGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKY 581
+ + N ++Q + AL KL + ++ T S I ++ +
Sbjct: 537 IVDIIEEVFNSVEASRYIIVQYGLFALTKLSARLGSSS--TASRIDKIIYSY-------K 587
Query: 582 RSTNFDIQERSVEFYEML---KLCQDALQDETEGLP 614
R+ N ++Q+RSVEF+ +L KL + L+ LP
Sbjct: 588 RNKNTEVQQRSVEFHLILNDSKLSKTILEPTPAPLP 623
>At1g60070 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 867
Score = 137 bits (344), Expect = 1e-31
Identities = 140/636 (22%), Positives = 281/636 (44%), Gaps = 93/636 (14%)
Query: 27 LKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAW 86
L D+I+ IR++ E+ + + + R + D + + + KL ++ M G+ +
Sbjct: 10 LSDMIRAIRASKTAAEE-RAVVRKECAAIRASINENDQDYRHRDLAKLMFIHMLGYPTHF 68
Query: 87 ANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVA 146
L++++S F +KR+GYL + ++LML TN LK+DL + +N+ + +G+A
Sbjct: 69 GQMECLKLIASPGFPEKRIGYLGLMLLLDERQEVLMLVTNSLKQDLNH--TNQYI-VGLA 125
Query: 147 LSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVST 206
L L I + E+ARD+ ++ +L P +RKKA ++ + P+ + ++ +
Sbjct: 126 LCALGNICSAEMARDLAPEVERLLQFRDPNIRKKAALCAIRIIRKVPDLSENFINPGAAL 185
Query: 207 LEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQ------------------ID 248
L+++ V+ V + E+ K + F E L++ I
Sbjct: 186 LKEKHHGVLITGVHLCTEICKVSSEALEYFRKKCTEGLVKTLRDIANSPYSPEYDVAGIT 245
Query: 249 NNWIIIRLLKLFTSLSK---EEPKLRYKILPKVLELMD--KTTAISVIYESINCIVKGQM 303
+ ++ IRLLKL L + + IL +V + K +++YE + I M
Sbjct: 246 DPFLHIRLLKLLRVLGQGDADASDCMNDILAQVASKTESNKNAGNAILYECVQTI----M 301
Query: 304 LEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDV 363
E++ +N L + + D N+RY++ + ++ + + ++ ++ +KD
Sbjct: 302 SIEENGGLRVLAINILGKFLSNRDNNIRYVALNMLMRSLTVDSQAVQRHRATILECVKDS 361
Query: 364 DISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKT 423
D SI+ + LEL + + +N+K L + LI + + V++Q + D+
Sbjct: 362 DASIQKRALELIYLLVNENNVKPLAKELI------EYLEVSEQDFKGDL----------- 404
Query: 424 VLDVCCINDYENINGDFDWY----LKILTDL-CIVSQDLNNLEVSTLLGDNFRNIMVKVP 478
+C I E + WY LK+L++ V +D+ + + ++ P
Sbjct: 405 TAKICSI--VEKFAPEKIWYIDQMLKVLSEAGTYVKEDVWHALIV---------VITNAP 453
Query: 479 SMRDAALEQLIKL--TTNDDIIAKLPNLLKEGIWCFGEYSELIDNCDTLVGI-------- 528
+ + L + T+ + + L L++ IWC GEY++L+ N ++ +
Sbjct: 454 DLHGYTVRALYRALHTSFEQVDISLETLVRVAIWCIGEYADLLVNNAGMLDLEDPITVTE 513
Query: 529 -----LLNKANK--LPDTVIQTM-IPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQK 580
++ A K L D + M + AL+K+ S + + R KS I Q
Sbjct: 514 SDAVDVVENAIKHHLSDVTTKAMALIALLKISSRFPSCSERVKSIIG-----------QN 562
Query: 581 YRSTNFDIQERSVEFYEMLKLCQDALQDETEGLPLL 616
S ++Q+RS+EF +++ Q+ E +P+L
Sbjct: 563 KGSFVLELQQRSLEFSSVIQKHQNIRSSLVERMPVL 598
>At1g23900 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 876
Score = 132 bits (332), Expect = 2e-30
Identities = 139/629 (22%), Positives = 280/629 (44%), Gaps = 84/629 (13%)
Query: 27 LKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAW 86
L+D+I+ IR+ E+ + + + + R + D + + + KL ++ M G+ +
Sbjct: 10 LRDMIRAIRACKTAAEE-RAVVRKECADIRALINEDDPHDRHRNLAKLMFIHMLGYPTHF 68
Query: 87 ANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVA 146
L++++S F +KR+GYL + ++LML TN LK+DL + SN+ V +G+A
Sbjct: 69 GQMECLKLIASPGFPEKRIGYLGLMLLLDERQEVLMLVTNSLKQDLNH--SNQYV-VGLA 125
Query: 147 LSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVST 206
L L I + E+ARD+ ++ ++ P +RKKA ++ + P+ + ++ S
Sbjct: 126 LCALGNICSAEMARDLAPEVERLIQFRDPNIRKKAALCSTRIIRKVPDLAENFVNAAASL 185
Query: 207 LEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQ------------------ID 248
L+++ V+ V + EL N F E LI+ I
Sbjct: 186 LKEKHHGVLITGVQLCYELCTINDEALEYFRTKCTEGLIKTLRDITNSAYQPEYDVAGIT 245
Query: 249 NNWIIIRLLKLFTSLSK---EEPKLRYKILPKVLELMD--KTTAISVIYESINCIVKGQM 303
+ ++ IRLL+L L + + L IL +V + K +V+YE + I M
Sbjct: 246 DPFLHIRLLRLLRVLGQGDADASDLMTDILAQVATKTESNKNAGNAVLYECVETI----M 301
Query: 304 LEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDV 363
ED +N L + + D N+RY++ + + + + ++ ++ +KD
Sbjct: 302 AIEDTNSLRVLAINILGRFLSNRDNNIRYVALNMLMKAITFDDQAVQRHRVTILECVKDP 361
Query: 364 DISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKT 423
D SIR + LEL + + + +N+ L + LI D + ++D+ + D+
Sbjct: 362 DASIRKRALELVTLLVNENNVTQLTKELI------DYLEISDEDFKEDLSAK-------- 407
Query: 424 VLDVCCINDYENINGDFDWYL-KILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRD 482
+C I E + + WY+ ++L LC E + D+ + ++ V S
Sbjct: 408 ---ICFI--VEKFSPEKLWYIDQMLKVLC---------EAGKFVKDDVWHALIVVISNAS 453
Query: 483 AALEQLIKLTTNDDI-IAKLPNLLKEGIWCFGEYSELIDNCDTLVGILLNKANKLPDTVI 541
++ + ++ L++ +WC GEY +L+ N ++GI + P TV
Sbjct: 454 ELHGYTVRALYKSVLTYSEQETLVRVAVWCIGEYGDLLVNNVGMLGI------EDPITVT 507
Query: 542 QTMIPALVKLFSTYANTEGRTKS--------------EISDLLSTLIAFMEQKYRSTNFD 587
++ +++ T N++ TK+ IS+ + +I ++QK S +
Sbjct: 508 ESDAVDVIEDAITRHNSDSTTKAMALVALLKLSSRFPSISERIKDII--VKQK-GSLLLE 564
Query: 588 IQERSVEFYEMLKLCQDALQDETEGLPLL 616
+Q+R++E+ ++ ++ + +P+L
Sbjct: 565 MQQRAIEYNSIVDRHKNIRSSLVDRMPVL 593
>At1g31730 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 933
Score = 131 bits (330), Expect = 4e-30
Identities = 141/612 (23%), Positives = 268/612 (43%), Gaps = 67/612 (10%)
Query: 25 KSLKDLIKGIRSNNETPEQLQDFLNQAIVECRE--EVKSPDFNMKTNAVLKLTYLEMYGF 82
K DL+K I E+ + L++ + R E P MK +++L Y+EM G
Sbjct: 23 KEFLDLVKSIGEARSKAEEDRIVLSEVDILKRRLLEPDIPKRKMK-EYIIRLVYIEMLGH 81
Query: 83 DMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVK 142
D ++ + +++ +N KR GYLA + +D D+++L N ++KDL+ S+ +
Sbjct: 82 DASFGYIYAVKMTHDDNLLLKRTGYLAVTLFLNEDHDLIILIVNTIQKDLR---SDNYLV 138
Query: 143 MGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSK 202
+ AL+ + ++ E + + +LN K VRKKA+ AL + + P S+ +S
Sbjct: 139 VCAALNAICRLINEETIPAVLPQVVELLNHQKEAVRKKAIMALHRFHRKSPSSVSHLVSN 198
Query: 203 FVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWI---------- 252
F L D D V+ A + + +L + + +L Q+ +
Sbjct: 199 FRKRLCDNDPGVMGATLCPLFDLISEDVNSYKDLVSSFVSILKQVTERRLPKSYDYHQMP 258
Query: 253 --IIRLLKLFTSLSKEEPKLRYKILPKVLELMDKTTAI--SVIYE---SINCIVKGQMLE 305
I+++ L S K + +L + D +T I +++YE I+CI+ L
Sbjct: 259 APFIQIMALLGSGDKNASDIMSMVLGDLFRKCDSSTNIGNAILYECIRCISCILPNPKLL 318
Query: 306 EDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVDI 365
E D + ++S NL+Y+ + KI+ + Q+ VI L+D D
Sbjct: 319 EAAADA-------ISKFLKSDSHNLKYMGIDGLGRLIKISPDIAEQHQLAVIDCLEDPDD 371
Query: 366 SIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVL 425
+++ K EL + + N++ +V +I + ++ H YK ++A
Sbjct: 372 TLKRKTFELLYKMTKSSNVEVIVDRMIDYMISINDNH-------------YKTEIASR-- 416
Query: 426 DVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVS----TLLGDNFRNIMVKVPS-M 480
C+ E W+++I+ + + DL N++V+ L+ + F S +
Sbjct: 417 ---CVELAEQFAPSNQWFIQIMNKVFEHAGDLVNIKVAHNLMRLIAEGFGEDDDDADSKL 473
Query: 481 RDAALEQLIKLTTNDDIIAKLPNLLKEGI-WCFGEYSELID--NCDTLVGILLNKAN--K 535
R +A+E ++L + KLP+L + I W GEY + + G L + A+
Sbjct: 474 RLSAVESYLQLISE----PKLPSLFLQVISWVLGEYGTADGKYSASYISGKLCDVADAYS 529
Query: 536 LPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRSTNFDIQERSVEF 595
+TV + AL+K+++ + GR D+L + +E+ S + D+Q+R+ E
Sbjct: 530 SDETVKGYAVSALMKIYA-FEIASGRK----VDVLPECQSLIEELLASHSTDLQQRAYEL 584
Query: 596 YEMLKLCQDALQ 607
+L L A++
Sbjct: 585 QALLALDARAVE 596
>CE25176 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 894
Score = 127 bits (319), Expect = 8e-29
Identities = 124/601 (20%), Positives = 269/601 (44%), Gaps = 62/601 (10%)
Query: 27 LKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAW 86
L+DLI+ +R+ E+ + +++ RE + D K + KL Y+ M G+ +
Sbjct: 29 LRDLIRQVRAARTMAEE-RAVVDRESANIRESFRDDDSPWKCRNIAKLLYIHMLGYPAHF 87
Query: 87 ANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVA 146
+++++ F KR+GYL A + S++ ML TN LK DL S + V G+A
Sbjct: 88 GQMECMKLVAHPRFTDKRIGYLGAMLLLDERSEVHMLVTNSLKNDLT--CSTQFVS-GLA 144
Query: 147 LSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVST 206
L L +I + E+ RD+ +++ ++ Y++KKA F++ + PE + + S
Sbjct: 145 LCTLGSICSAEMCRDLANEVEKIIKQNNAYLKKKAALCAFRIVRKVPELMEVFIPCTRSL 204
Query: 207 LEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEML-----------------IQIDN 249
L +++ V+ A +++ E+ + +P F L+ ++ I +
Sbjct: 205 LGEKNHGVLMGATTLVTEMCEKSPDVLNHFKKLVPNLVRILKNLLMSGYSPEHDVTGISD 264
Query: 250 NWIIIRLLKLFTSLSKEEPKLRYK---ILPKVLELMD--KTTAISVIYESINCIVKGQML 304
++ +++L+L L K++ ++ + IL +V + K +++YE++ I++
Sbjct: 265 PFLQVKILRLLRVLGKDDVRVTEEMNDILAQVATNTETAKNVGNAILYETVLTIME---- 320
Query: 305 EEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVD 364
+ + +N L + + D N+RY++ ++++ + ++ +V+ LKD D
Sbjct: 321 IKSESGLRILAVNILGRFLLNTDKNIRYVALNTLLKTVHVDYQAVQRHRNVVVECLKDPD 380
Query: 365 ISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTV 424
ISIR + +ELC + + NI + + ++ D ++ ++ I
Sbjct: 381 ISIRKRAMELCFALMNRTNIAIMTKEVLIFLETADAEFKSECASRMYIAT---------- 430
Query: 425 LDVCCINDYENINGDFDWYLK-ILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDA 483
E + + +W+L ++T L + + + + VS ++ ++ ++
Sbjct: 431 ---------ERYSPNHEWHLDTMITVLRLAGKYVPDEVVSCMI-----QMISANEQLQSY 476
Query: 484 ALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNCDTLVGILLNKANKLPDTVIQT 543
A+ QL D I A+ LL+ W GE+ +L+ + +++ + + V ++
Sbjct: 477 AVSQLYHAAQKDAINAQ--PLLQVAFWTIGEFGDLLLQPTDVDSTPISENDVVG--VFES 532
Query: 544 MIP-ALVKLFSTYANTEGRTK--SEISDLLSTLIAFMEQKYRSTNFDIQERSVEFYEMLK 600
++P AL L++ K + + A + ++Q+RSVEF +L
Sbjct: 533 VLPSALTSLWTKCYGVTALAKLGTRFQSTGDRIGALVRMNQAHIQLELQQRSVEFNVILN 592
Query: 601 L 601
L
Sbjct: 593 L 593
>7291008 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 951
Score = 124 bits (312), Expect = 5e-28
Identities = 94/389 (24%), Positives = 180/389 (46%), Gaps = 32/389 (8%)
Query: 27 LKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAW 86
L+DLI+ IR+ E+ + +N+ R + D + + KL Y+ M G+ +
Sbjct: 23 LRDLIRQIRAARTAAEE-RAVVNKECAYIRSTFREEDSVWRCRNIAKLLYIHMLGYPAHF 81
Query: 87 ANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVA 146
L++ +S F KR+GYL A + D+ +L TN LK DL S+ +G+A
Sbjct: 82 GQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLN---SSTQFVVGLA 138
Query: 147 LSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVST 206
L L I +PE+ARD+ ++ ++ S Y+RKKA F+V + PE + L S
Sbjct: 139 LCTLGAIASPEMARDLASEVERLMKSPNTYIRKKATLCAFRVIRRVPELMEIFLPATRSL 198
Query: 207 LEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWII------------- 253
L +++ ++ V++I E+ +++ + F ++ L++I N I+
Sbjct: 199 LSEKNHGILITGVTLITEMCENSSDTLMHFKKIV-PNLVRILKNLILGGYSPEHDVSGVS 257
Query: 254 -----IRLLKLFTSLSKEEP---KLRYKILPKVLELMD--KTTAISVIYESINCIVKGQM 303
+++L+L L +P + IL +V + K +++YE++ I M
Sbjct: 258 DPFLQVKILRLLRILGHNDPDASEAMNDILAQVATNTETSKNVGNTILYETVLSI----M 313
Query: 304 LEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDV 363
+ +N L + + D N+RY++ + + ++ ++ LKD
Sbjct: 314 DIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNTLLRTVHADTSAVQRHRTTILECLKDP 373
Query: 364 DISIRTKVLELCSGIASTDNIKNLVRILI 392
D+SIR + +EL + + NI+ + + L+
Sbjct: 374 DVSIRRRAMELSFALINAQNIRTMTKELL 402
>Hs6671551 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 1137
Score = 122 bits (307), Expect = 2e-27
Identities = 131/621 (21%), Positives = 269/621 (43%), Gaps = 68/621 (10%)
Query: 23 FEKSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKT--NAVLKLTYLEMY 80
F L L++GI + E+ + + Q + + V +P +K +++L Y EM
Sbjct: 32 FSSRLGSLVRGITALTSKHEE-EKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEML 90
Query: 81 GFDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNET 140
G+D ++ H +++ N +KRVGYLA S ++ ++L+L N + KDL+ S
Sbjct: 91 GYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQ---STNL 147
Query: 141 VKMGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGL 200
V++ +AL+ +S I E+ + + L K VR+KAV AL+K L P ++
Sbjct: 148 VEVCMALTVVSQIFPREMIPAVLPLIEDKLQHSKEIVRRKAVLALYKFHLIAPNQVQHIH 207
Query: 201 SKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNN---------- 250
KF L D D V++A++ + + K N + + +L Q+
Sbjct: 208 IKFRKALCDRDVGVMAASLHIYLRMIKENSSGYKDLTGSFVTILKQVVGGKLPVEFNYHS 267
Query: 251 ----WIIIRLLKLFTSLSKEEPK---LRYKILPKVLEL--MDKTTAISVIYESINCIV-- 299
W+ I+LL++ L K++ + L Y +L + L ++ ++++E ++ +
Sbjct: 268 VPAPWLQIQLLRILGLLGKDDQRTSELMYDVLDESLRRAELNHNVTYAILFECVHTVYSI 327
Query: 300 --KGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVI 357
K ++LE+ A +C+ V S NL+Y+ ++ + + +Q+ +I
Sbjct: 328 YPKSELLEK-----AAKCIG---KFVLSPKINLKYLGLKALTYVIQQDPTLALQHQMTII 379
Query: 358 GLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYK 417
L D I+ + LEL I + NI +V+ +++ Q + + +N
Sbjct: 380 ECLDHPDPIIKRETLELLYRITNAQNITVIVQKMLEYL---------HQSKEEYVIVNLV 430
Query: 418 VKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVST----LLGDNFRNI 473
K+A+ E D W+++ + + V D+ + ++ LL + F +
Sbjct: 431 GKIAELA---------EKYAPDNAWFIQTMNAVFSVGGDVMHPDIPNNFLRLLAEGFDD- 480
Query: 474 MVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNCDTLVGILLNKA 533
+ +R A++ + L +++ L+ W GEYS L+D +T ++
Sbjct: 481 ETEDQQLRLYAVQSYLTLLDMENVFYP-QRFLQVMSWVLGEYSYLLDK-ETPEEVIAKLY 538
Query: 534 NKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRSTNFDIQ--ER 591
L + + + A + T ++ + + + L+ ++ R F+++
Sbjct: 539 KLLMNDSVSSETKAWLIAAVTKLTSQAHSSNTVERLIHEFTISLDTCMRQHAFELKHLHE 598
Query: 592 SVEFYEML----KLCQDALQD 608
+VE + L + C+D + D
Sbjct: 599 NVELMKSLLPVDRSCEDLVVD 619
>At5g22780 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 1013
Score = 120 bits (300), Expect = 1e-26
Identities = 131/573 (22%), Positives = 254/573 (43%), Gaps = 81/573 (14%)
Query: 67 KTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATN 126
K V K+ Y+ M G+D+ + + + ++S+ + +K+VGY+ S ++ D L LA N
Sbjct: 49 KKKYVWKMLYIHMLGYDVDFGHMEAVSLISAPKYPEKQVGYIVTSCLLNENHDFLKLAIN 108
Query: 127 LLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDL--FLMLNSGKPYVRKKAVTA 184
++ D+ NET + +AL+ + I + A + D+ L+ +S +P VRKKA
Sbjct: 109 TVRNDIIG--RNETFQC-LALTLVGNIGGRDFAESLAPDVQKLLISSSCRPLVRKKAALC 165
Query: 185 LFKVFLQYPESLR-DG-LSKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYE 242
L ++F + P+++ DG + L++ D V++++ S++ L +N + P +
Sbjct: 166 LLRLFRKNPDAVNVDGWADRMAQLLDERDLGVLTSSTSLLVALVSNNHEAYSSCLPKCVK 225
Query: 243 MLIQIDNN---------------WI---IIRLLKLFTSLSKEEPKLR---YKILPKVLEL 281
+L ++ N W+ +R L+ F ++ E+P R +++L ++L
Sbjct: 226 ILERLARNQDVPQEYTYYGIPSPWLQVKAMRALQYFPTI--EDPSTRKALFEVLQRILMG 283
Query: 282 MD-------KTTAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYIS 334
D + +V++E+++ + M + + + QC+ L + +PN+RY+
Sbjct: 284 TDVVKNVNKNNASHAVLFEALSLV----MHLDAEKEMMSQCVALLGKFISVREPNIRYLG 339
Query: 335 CVLFYHIGKIN--FEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILI 392
+ + + I ++ +I LKD DISIR + L+L G+ N K++V L+
Sbjct: 340 LENMTRMLMVTDVQDIIKKHQSQIITSLKDPDISIRRRALDLLYGMCDVSNAKDIVEELL 399
Query: 393 KQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCI 452
Q++ + ++ L+ K + E D WY+ ++ L
Sbjct: 400 -QYLSTAEFSMREE-------LSLKAAILA-----------EKFAPDLSWYVDVILQLID 440
Query: 453 VSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCF 512
+ D + D + ++ V + D K D IA ++K +
Sbjct: 441 KAGDF-------VSDDIWFRVVQFVTNNEDLQPYAASKAREYMDKIAIHETMVKVSAYIL 493
Query: 513 GEYSELID-----NCDTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEIS 567
GEY L+ + L IL KLP TV IP L+ STYA +
Sbjct: 494 GEYGHLLARQPGCSASELFSIL---HEKLP-TVSTPTIPILL---STYAKLLMHAQPPDP 546
Query: 568 DLLSTLIAFMEQKYRSTNFDIQERSVEFYEMLK 600
+L + A ++ + +IQ+R+VE++E+ K
Sbjct: 547 ELQKKVWAVFKKYESCIDVEIQQRAVEYFELSK 579
>At5g22770 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 1012
Score = 120 bits (300), Expect = 1e-26
Identities = 129/573 (22%), Positives = 255/573 (43%), Gaps = 81/573 (14%)
Query: 67 KTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATN 126
K V K+ Y+ M G+D+ + + + ++S+ + +K+VGY+ S ++ D L LA N
Sbjct: 49 KKKYVWKMLYIHMLGYDVDFGHMEAVSLISAPKYPEKQVGYIVTSCLLNENHDFLKLAIN 108
Query: 127 LLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDL--FLMLNSGKPYVRKKAVTA 184
++ D+ NET + +AL+ + I + A + D+ L+ +S +P VRKKA
Sbjct: 109 TVRNDIIG--RNETFQC-LALTLVGNIGGRDFAESLAPDVQKLLISSSCRPLVRKKAALC 165
Query: 185 LFKVFLQYPESLR-DG-LSKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYE 242
L ++F + P+++ DG + L++ D V++++ S++ L +N + P +
Sbjct: 166 LLRLFRKNPDAVNVDGWADRMAQLLDERDLGVLTSSTSLLVALVSNNHEAYSSCLPKCVK 225
Query: 243 MLIQIDNN---------------WI---IIRLLKLFTSLSKEEPKLR---YKILPKVLEL 281
+L ++ N W+ +R L+ F ++ E+P R +++L ++L
Sbjct: 226 ILERLARNQDVPQEYTYYGIPSPWLQVKAMRALQYFPTI--EDPSTRKALFEVLQRILMG 283
Query: 282 MD-------KTTAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYIS 334
D + +V++E+++ + M + + + QC+ L + +PN+RY+
Sbjct: 284 TDVVKNVNKNNASHAVLFEALSLV----MHLDAEKEMMSQCVALLGKFISVREPNIRYLG 339
Query: 335 CVLFYHIGKIN--FEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILI 392
+ + + I ++ +I LKD DISIR + L+L G+ N K++V L+
Sbjct: 340 LENMTRMLMVTDVQDIIKKHQSQIITSLKDPDISIRRRALDLLYGMCDVSNAKDIVEELL 399
Query: 393 KQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCI 452
Q++ + ++ L+ K + E D WY+ ++ L
Sbjct: 400 -QYLSTAEFSMREE-------LSLKAAILA-----------EKFAPDLSWYVDVILQLID 440
Query: 453 VSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCF 512
+ D + ++ + N P A E L K+ ++ ++K +
Sbjct: 441 KAGDFVSDDIWFRVVQFVTNNEDLQPYAASKAREYLDKIAIHE-------TMVKVSAYIL 493
Query: 513 GEYSELID-----NCDTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEIS 567
GEY L+ + L IL KLP T+ IP L+ STYA +
Sbjct: 494 GEYGHLLARQPGCSASELFSIL---HEKLP-TISTPTIPILL---STYAKLLMHAQPPDP 546
Query: 568 DLLSTLIAFMEQKYRSTNFDIQERSVEFYEMLK 600
+L + A ++ + +IQ+R+VE++E+ K
Sbjct: 547 ELQKKVWAVFKKYESCIDVEIQQRAVEYFELSK 579
>Hs18104998 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 825
Score = 119 bits (298), Expect = 2e-26
Identities = 132/632 (20%), Positives = 263/632 (40%), Gaps = 90/632 (14%)
Query: 27 LKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAW 86
L++LI+ IR+ E+ ++ + + R + D + V KL Y+ M G+ +
Sbjct: 7 LRELIRTIRTARTQAEE-REMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHF 65
Query: 87 ANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVA 146
L++++S F KR+GYL A + D+ +L TN +K DL + S + V+ G+A
Sbjct: 66 GQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNH--STQFVQ-GLA 122
Query: 147 LSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVST 206
L L + + E+ RD+ ++ +L + Y+RKKA V + PE + L +
Sbjct: 123 LCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNL 182
Query: 207 LEDEDTSVVSAAVSVICELAKHNPGPFIQF--SPLLYEMLIQIDNNWI------------ 252
L +++ V+ +V ++ E+ + +P F S L L++I N I
Sbjct: 183 LNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKSLQLVPQLVRILKNLIMSGYSPEHDVSG 242
Query: 253 ---------IIRLLKLFTSLSKEEPKLRYKILPKVLELMD--KTTAISVIYESINCIVKG 301
I+RLL++ + + IL +V + K +++YE++ I
Sbjct: 243 ISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTI--- 299
Query: 302 QMLEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLK 361
M + + +N L + + D N+RY++ + + + ++ ++ LK
Sbjct: 300 -MDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLK 358
Query: 362 DVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVA 421
D+D+SI+ + +EL + + +NI+ +++ L+ F+D +K A
Sbjct: 359 DLDVSIKRRAMELSFALVNGNNIRGMMKELL-YFLD-------------SCEPEFKADCA 404
Query: 422 KTVLDVCCINDYENINGDFDWYL-KILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSM 480
+ E W++ I+ L + + V L+ ++ M
Sbjct: 405 SGIFLAA-----EKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLI-----QLITNSVEM 454
Query: 481 RDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELI----------------DNCDT 524
+++L K D ++ P L++ WC GEY +L+ + D
Sbjct: 455 HAYTVQRLYKAILGD--YSQQP-LVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDI 511
Query: 525 LVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRST 584
L +L+ +N + A++KL + + T R K +S S S
Sbjct: 512 LESVLI--SNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS-----------SI 558
Query: 585 NFDIQERSVEFYEMLKLCQDALQDETEGLPLL 616
+ ++Q+R+VE+ + K E +P++
Sbjct: 559 DVELQQRAVEYNALFKKYDHMRSALLERMPVM 590
>SPBC691.03c [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 878
Score = 117 bits (294), Expect = 6e-26
Identities = 130/627 (20%), Positives = 277/627 (43%), Gaps = 82/627 (13%)
Query: 25 KSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDM 84
K L+ I +RS E+ + + A + + + + + V KL Y+ M G+ +
Sbjct: 8 KGLRAFISDLRSLEHDDEEKRVNVELAKIRAKFQSSTLSAYDRKKYVSKLLYIYMLGYPI 67
Query: 85 AWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMG 144
+ + +++S + +K +GYLA + ++ +++ L N +KKDL LS+++++
Sbjct: 68 TFGHMEAAKLLSGTKYSEKLIGYLAVALLLNENHELMKLVINSIKKDL---LSHDSLQNS 124
Query: 145 VALSGLSTIVTPELARDICDDLF--LMLNSGKPYVRKKAVTALFKVFLQYPESLR-DGLS 201
+AL ++ I EL + D++ LM S + VR+K+ AL ++ ++P+ + +
Sbjct: 125 LALHTIANIGGRELCETVYYDIYKLLMSASNENIVRQKSALALLHIYRKFPDLINPEWFE 184
Query: 202 KFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFS---------PLLYE-------MLI 245
V L D+D + VS AVS L + +F+ +++E +
Sbjct: 185 PIVMILGDDDLN-VSLAVSNFVNLIVIREPKYQKFAYGKAVGKLKNIVFEHGYSSDYLYY 243
Query: 246 QIDNNWIIIRLLKLFTSLSKEEPK------LRYKILPKVLELMDKTTAISVIYESINCI- 298
+ W+ + L ++ L+ E P ++L ++L L + + + + ++N I
Sbjct: 244 SVPCPWLQVNLCRIL--LACERPSDNPTRATLIRVLDRILSLPNDNSNVQQV-NAVNAIL 300
Query: 299 ---VKGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEF--IMQYD 353
+K L ++ + +C++ L ++ + N+RY++ ++ + Y
Sbjct: 301 FEAIKLAFLVDESHSLYEKCMDRLADMIADKESNIRYLAFETTAYLISCGHSITSLKHYK 360
Query: 354 KLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIP 413
+L++ L+ D+S+R K LEL + +N K +V L++ +D+V D
Sbjct: 361 ELILSSLRYKDVSLRKKSLELLYMMCDEENAKLIVADLLQYLPHLDSVTQED-------- 412
Query: 414 LNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNI 473
L KV + E D++WY+ + L ++ + ++
Sbjct: 413 LISKVAIIS-----------ETFATDYEWYVDVTIQLLRIA----GKSADDGVWHQLVHV 457
Query: 474 MVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELI-DNCDT----LVGI 528
+V +++ A ++L L ++ I L+K G + GE+ LI D D+
Sbjct: 458 IVNNEEIQEYATKRLFSLLQSETI---HECLVKAGGYVLGEFGHLITDYPDSQPVHQFST 514
Query: 529 LLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRS-TNFD 587
+ K N + ++ L+KL + + L+ IA + Q+Y + N +
Sbjct: 515 IYRKLNVSSPSTRVLLLTTLIKL------------ANLQPELNDRIAKVFQEYSTIINPE 562
Query: 588 IQERSVEFYEMLKLCQDALQDETEGLP 614
+Q+R+ E+ ++LK+ +D LQ + +P
Sbjct: 563 VQQRACEYLQLLKMPRDFLQLVCDEVP 589
>CE28680 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 925
Score = 109 bits (273), Expect = 2e-23
Identities = 135/638 (21%), Positives = 267/638 (41%), Gaps = 93/638 (14%)
Query: 25 KSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSP---DFNMKTNAVLKLTYLEMYG 81
+ L I IR+ +L+ +N+ + R + K D K V KL ++ + G
Sbjct: 10 RGLAVFISDIRNCKSKEAELKR-INKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLG 68
Query: 82 FDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETV 141
D+ + + + ++SSN + +K++GYL S + SD++ L ++ DL S V
Sbjct: 69 NDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQGIRNDL---TSRNPV 125
Query: 142 KMGVALSGLSTIVTPELARDICDDLFLMLNSGK--PYVRKKAVTALFKVFLQYPESLRDG 199
+ +AL +S + + E+ C DL +L SG+ +V++ A + K+F P+S + G
Sbjct: 126 HVNLALQCISNMGSREMVEAFCTDLPKLLVSGETIDFVKQSAALCILKLFRNSPDSFQPG 185
Query: 200 --LSKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQI---------- 247
S+ V L D VV++A S+I L+K P + PL L +I
Sbjct: 186 DYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATYTDLQD 245
Query: 248 ------DNNWIIIRLLKLFTSL-SKEEPKLRYKIL-------------PKVLELMDKTTA 287
W+ ++LL+L + ++P + ++L PK ++
Sbjct: 246 YTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKAQDAPKSKKVQHSNAK 305
Query: 288 ISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYIS----CVLFYHIGK 343
+V++E+I I+ ++ + C N L + + + NLRY++ C+L +
Sbjct: 306 NAVLFEAIALIIH---MDSEPQLLVRAC-NQLGTFLSHRETNLRYLALESMCLL--ATSE 359
Query: 344 INFEFIMQYDKLVIGLLK-DVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVH 402
+ + + ++ +I LK + D+S+R + ++L + N +V ++ D
Sbjct: 360 FSHDAVKKHQDTIINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAEMLAYLETAD--- 416
Query: 403 VNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEV 462
Y ++ + VL V + E D+ WY+ ++ L ++ D V
Sbjct: 417 -------------YSIR-EEMVLKVAIL--AEKYATDYTWYVDVILKLIRIAGDY----V 456
Query: 463 STLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNC 522
S + I+V ++ A + + + A N++K G + GE+ I
Sbjct: 457 SEEVWYRVIQIVVNREDVQGYAAKTVFEALQRP---ACHENMVKVGGYILGEFGNFIAGD 513
Query: 523 DTLVG-----ILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFM 577
+ +L +K + T ++ +K + N K + + T
Sbjct: 514 ERSTAKIQFELLHSKFHLCSITTRCLLLTTYIK----FCNLFPEIKPLVQQVFQT----- 564
Query: 578 EQKYRSTNFDIQERSVEFYEMLKLC-QDALQDETEGLP 614
+ R+ + ++Q+RS+E+ +M KL D L E +P
Sbjct: 565 DHNLRNPDAELQQRSIEYLQMTKLASNDVLATILEVMP 602
>Hs4503843 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 785
Score = 109 bits (272), Expect = 2e-23
Identities = 137/674 (20%), Positives = 270/674 (39%), Gaps = 94/674 (13%)
Query: 27 LKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAW 86
L+DLI+ IR +T Q ++ + + R + D + + KL Y+ M G+ +
Sbjct: 8 LQDLIEEIRGA-KTQAQEREVIQKECAHIRASFRDGDPVHRHRQLAKLLYVHMLGYPAHF 66
Query: 87 ANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVA 146
L++++S+ F KRVGYL A + D +L TN +K DL + G+A
Sbjct: 67 GQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPV---QGLA 123
Query: 147 LSGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVST 206
L LST+ + E+ RD+ ++ +L PYVRKKA+ + + PE L
Sbjct: 124 LCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKVPELSSVFLPPCAQL 183
Query: 207 LEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQIDNNWI-------------- 252
L + ++ +++I EL + +P F ++ L+ I +
Sbjct: 184 LHERHHGILLGTITLITELCERSPAALRHFRKVV-PQLVHILRTLVTMGYSTEHSISGVS 242
Query: 253 -------IIRLLKLFTSLSKEEPKLRYKILPKVLELMD--KTTAISVIYESINCIVKGQM 303
I+RLL++ +E + +L +V D + +V++E++ I M
Sbjct: 243 DPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTI----M 298
Query: 304 LEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDV 363
+N L + + D N+RY++ + + + + ++ V+ L++
Sbjct: 299 DIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRET 358
Query: 364 DISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKT 423
D S+ + LEL + ++ N++ +++ L Q P + + A
Sbjct: 359 DASLSRRALELSLALVNSSNVRAMMQEL--------------QAFLESCPPDLRADCASG 404
Query: 424 VLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDA 483
+L + D L +LT +D ++ L+G V + +A
Sbjct: 405 IL-LAAERFAPTKRWHIDTILHVLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNA 463
Query: 484 ALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELI--DNCDTLVGILLNKANKLP--DT 539
E I++ P L++ WC GEY +L+ NC+ + + +++ L +
Sbjct: 464 LAED----------ISQQP-LVQVAAWCIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEK 512
Query: 540 VIQT----------MIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRSTNFDIQ 589
V+Q+ + AL+KL + R + +S S L + ++Q
Sbjct: 513 VLQSHMSLPATRGYALTALMKLSTRLCGDNNRIRQVVSIYGSCL-----------DVELQ 561
Query: 590 ERSVEFYEMLKLCQDALQDETEGLPLLITDVLPSLFNEYELGPMSHGQQQQLVKALTLDL 649
+R+VE+ + + E +PL+ D GP + + ++ +A L
Sbjct: 562 QRAVEYDTLFRKYDHMRAAILEKMPLVERD-----------GPQADEEAKESKEAAQLSE 610
Query: 650 DTPFLSSVELEELM 663
P + + +L+
Sbjct: 611 AAPVPTEPQASQLL 624
>7296210 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 932
Score = 109 bits (272), Expect = 2e-23
Identities = 136/635 (21%), Positives = 267/635 (41%), Gaps = 86/635 (13%)
Query: 25 KSLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSP---DFNMKTNAVLKLTYLEMYG 81
+ L I IR N ++ E +N+ + R + K D K V KL ++ + G
Sbjct: 2 RGLAVFISDIR-NCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLG 60
Query: 82 FDMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETV 141
D+ + + + ++SSN + +K++GYL S +SD++ L +K DL+ S V
Sbjct: 61 HDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQ---SRNPV 117
Query: 142 KMGVALSGLSTIVTPELARDICDDLFLMLNSG--KPYVRKKAVTALFKVFLQYPESLRDG 199
+ +AL ++ I + ++A +++ +L SG V++ A L ++F P+ + G
Sbjct: 118 HVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGG 177
Query: 200 --LSKFVSTLEDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQI---------- 247
S+ + L D+ VV+AA S+I L K NP + L L +I
Sbjct: 178 EWTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRLSRIVTASYTDLQD 237
Query: 248 ------DNNWIIIRLLKLFTSLS--KEEPKLRYKI-------------LPKVLELMDKTT 286
W+ ++LL+L + + EE +R ++ PK ++
Sbjct: 238 YTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNA 297
Query: 287 AISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINF 346
+V++E+IN I+ + + + + N L + + + NLRY++ H+ F
Sbjct: 298 KNAVLFEAINLIIH----SDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEF 353
Query: 347 --EFIMQYDKLVIGLLK-DVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHV 403
E + ++ ++VI +K + D+S+R ++L + N + +V+ ++ D
Sbjct: 354 SHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETAD---- 409
Query: 404 NDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVS 463
Y ++ + VL V + E D+ WY+ ++ +L ++ D VS
Sbjct: 410 ------------YSIR-EEMVLKVAIL--AEKYATDYTWYVDVILNLIRIAGDY----VS 450
Query: 464 TLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNCD 523
+ I++ ++ A + + + A N++K G + GE+ LI
Sbjct: 451 EEVWYRVIQIVINREEVQGYAAKTVFEAL---QAPACHENMVKVGGYILGEFGNLIAGDS 507
Query: 524 TLVGILLNKANKLPDTVIQTMIPALVKLFSTY---ANTEGRTKSEISDLLSTLIAFMEQK 580
++ K + M AL L STY N ++ I D+
Sbjct: 508 RSAPLVQFKLLHSKYHLCSPMTRAL--LLSTYIKFINLFPEIRTNIQDVFR-----QHSN 560
Query: 581 YRSTNFDIQERSVEFYEM-LKLCQDALQDETEGLP 614
RS + ++Q+R+ E+ ++ + D L E +P
Sbjct: 561 LRSADAELQQRASEYLQLSIVASTDVLATVLEEMP 595
>Hs19913416 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 955
Score = 99.0 bits (245), Expect = 3e-20
Identities = 126/614 (20%), Positives = 257/614 (41%), Gaps = 90/614 (14%)
Query: 48 LNQAIVECREEVKSP---DFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKR 104
+N+ + R + K D K V KL ++ + G D+ + + + ++SSN + +K+
Sbjct: 33 INKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQ 92
Query: 105 VGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICD 164
+GYL S +S+++ L N +K DL S M +AL ++ + + E+
Sbjct: 93 IGYLFISVLVNSNSELIRLINNAIKNDL---ASRNPTFMCLALHCIANVGSREMGEAFAA 149
Query: 165 DL--FLMLNSGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVS 220
D+ L+ V++ A L +++ P+ + G ++ V L D+ VV+AAVS
Sbjct: 150 DIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVS 209
Query: 221 VICELAKHNPGPFIQFSPLLYEMLIQIDNN----------------WIIIRLLKLFTSL- 263
+I L K NP F L L +I ++ W+ ++LL+L
Sbjct: 210 LITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYP 269
Query: 264 SKEEPKLRYKIL-------------PKVLELMDKTTAISVIYESINCIVKGQMLEEDDYD 310
E+ ++ +++ PK ++ ++++E+I+ I+ + + +
Sbjct: 270 PPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIH----YDSEPN 325
Query: 311 TAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINF--EFIMQYDKLVIGLLK-DVDISI 367
+ N L +Q + NLRY++ + F E + + VI LK + D+S+
Sbjct: 326 LLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSV 385
Query: 368 RTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDV 427
R + +L + N K +V +++ + D ++ +I L + K +
Sbjct: 386 RQRAADLLYAMCDRSNAKQIVSEMLRY------LETADYAIREEIVLKVAILAEKYAV-- 437
Query: 428 CCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQ 487
D+ WY+ + +L ++ D + EV +R ++++ + RD
Sbjct: 438 -----------DYSWYVDTILNLIRIAGDYVSEEVW------YR--VLQIVTNRDDVQGY 478
Query: 488 LIKLTTNDDIIAKL--PNLLKEGIWCFGEYSELI----DNCDTLVGILLNKANKLPDTVI 541
K T + + A N++K G + GE+ LI + + LL+ L
Sbjct: 479 AAK-TVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVAT 537
Query: 542 QTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRSTNFDIQERSVEFYEMLKL 601
+ + L+ + + N TK+ I +L + R+ + ++Q+R+VE+ + +
Sbjct: 538 RAL---LLSTYIKFINLFPETKATIQGVLRA-----GSQLRNADVELQQRAVEYLTLSSV 589
Query: 602 CQ-DALQDETEGLP 614
D L E +P
Sbjct: 590 ASTDVLATVLEEMP 603
>Hs19913414 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 977
Score = 99.0 bits (245), Expect = 3e-20
Identities = 126/614 (20%), Positives = 257/614 (41%), Gaps = 90/614 (14%)
Query: 48 LNQAIVECREEVKSP---DFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKR 104
+N+ + R + K D K V KL ++ + G D+ + + + ++SSN + +K+
Sbjct: 33 INKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQ 92
Query: 105 VGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICD 164
+GYL S +S+++ L N +K DL S M +AL ++ + + E+
Sbjct: 93 IGYLFISVLVNSNSELIRLINNAIKNDL---ASRNPTFMCLALHCIANVGSREMGEAFAA 149
Query: 165 DL--FLMLNSGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVS 220
D+ L+ V++ A L +++ P+ + G ++ V L D+ VV+AAVS
Sbjct: 150 DIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVS 209
Query: 221 VICELAKHNPGPFIQFSPLLYEMLIQIDNN----------------WIIIRLLKLFTSL- 263
+I L K NP F L L +I ++ W+ ++LL+L
Sbjct: 210 LITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYP 269
Query: 264 SKEEPKLRYKIL-------------PKVLELMDKTTAISVIYESINCIVKGQMLEEDDYD 310
E+ ++ +++ PK ++ ++++E+I+ I+ + + +
Sbjct: 270 PPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIH----YDSEPN 325
Query: 311 TAHQCLNHLESLVQSLDPNLRYISCVLFYHIGKINF--EFIMQYDKLVIGLLK-DVDISI 367
+ N L +Q + NLRY++ + F E + + VI LK + D+S+
Sbjct: 326 LLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSV 385
Query: 368 RTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDV 427
R + +L + N K +V +++ + D ++ +I L + K +
Sbjct: 386 RQRAADLLYAMCDRSNAKQIVSEMLRY------LETADYAIREEIVLKVAILAEKYAV-- 437
Query: 428 CCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQ 487
D+ WY+ + +L ++ D + EV +R ++++ + RD
Sbjct: 438 -----------DYSWYVDTILNLIRIAGDYVSEEVW------YR--VLQIVTNRDDVQGY 478
Query: 488 LIKLTTNDDIIAKL--PNLLKEGIWCFGEYSELI----DNCDTLVGILLNKANKLPDTVI 541
K T + + A N++K G + GE+ LI + + LL+ L
Sbjct: 479 AAK-TVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVAT 537
Query: 542 QTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRSTNFDIQERSVEFYEMLKL 601
+ + L+ + + N TK+ I +L + R+ + ++Q+R+VE+ + +
Sbjct: 538 RAL---LLSTYIKFINLFPETKATIQGVLRA-----GSQLRNADVELQQRAVEYLTLSSV 589
Query: 602 CQ-DALQDETEGLP 614
D L E +P
Sbjct: 590 ASTDVLATVLEEMP 603
>CE28513 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 979
Score = 92.4 bits (228), Expect = 3e-18
Identities = 84/377 (22%), Positives = 174/377 (45%), Gaps = 38/377 (10%)
Query: 288 ISVIYESINCIVKG--QMLEEDDYDTAHQ-CLNHLESLVQSLDPNLRYISCVLFYHIGKI 344
+S++YE IN ++ + D+ + Q C+ L L++ D NL+Y+ + I K
Sbjct: 1 MSLLYECINTVIAVLISISAGGDHTASIQLCVQKLGVLIEDSDQNLKYLGLLAMGKILKT 60
Query: 345 NFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVN 404
+ + + + +V+ L D D SIR + L+L G+ S NI +V+ L++ + H
Sbjct: 61 HPKAVQAHKDIVLRCLDDKDESIRIRSLDLLYGMVSKKNIVEIVKKLMEHVEAAEGSH-- 118
Query: 405 DQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVST 464
Y+ ++ ++ +C ++Y+ I +F+WY+ +L +L V E
Sbjct: 119 -----------YRDELLSRIIGICSWSNYQYIT-NFEWYISVLVELTKV----EGTEHGA 162
Query: 465 LLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDII--------AKLPNLLKEGIWCFGEYS 516
+ + +++ V+V S+R ++ Q+ L N ++ + + +L W GEYS
Sbjct: 163 KIAEQIQDVTVRVESIRHFSVSQMALLVENAHVLLAGSAQQRSNMCEVLLAAAWICGEYS 222
Query: 517 ELIDNCD-TLVGILLNKANKLPDTVIQTMIPALVKLF-STYANTEGRTKSEISDLLSTL- 573
+ + N L +L K + +P ++ + + KL+ S + E + D L L
Sbjct: 223 QHVRNQQGVLESMLKAKPSVMPGHILSVYVQNIGKLYCSLMSQAEEEDDWDAIDSLDNLM 282
Query: 574 IAFMEQKYRSTNFDIQERSVEFYEMLKLCQDALQDETEGLPLLITDVLPSLFNEYELGPM 633
++ + Q S + + QER+ ++++ + QD + + + L+ + EL P+
Sbjct: 283 LSKLPQFELSEHLEAQERACNLMAIIRIVEKLHQDRQK-----MGSEVQKLY-DGELNPV 336
Query: 634 SHGQQQQLVKALTLDLD 650
+ Q+++ LDLD
Sbjct: 337 ATKAQRKVPVPDGLDLD 353
>At4g23460 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 893
Score = 92.4 bits (228), Expect = 3e-18
Identities = 126/593 (21%), Positives = 241/593 (40%), Gaps = 63/593 (10%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E +EE+ S + + +AV K+ G D++ V+ M + N + K++ YL
Sbjct: 17 IPELKEELNSQYKDKRKDAVKKVIAAMTVGKDVSSLFTDVVNCMQTENLELKKLVYLYLI 76
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ +LA N KD + N ++ +A+ + I ++ +CD L L
Sbjct: 77 NYAKSQPDLAILAVNTFVKDSQDP--NPLIR-ALAVRTMGCIRVDKITEYLCDPLQKCLK 133
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVSVICELAKHN 229
PYVRK A + K+F E + D L + D + VV+ AV+ + E+ +++
Sbjct: 134 DDDPYVRKTAAICVAKLFDINAELVEDRGFLEALKDLISDNNPMVVANAVAALAEIQENS 193
Query: 230 PGPFIQFSPLLYEMLIQIDNN---WIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKTT 286
P + + + L+ N W + +L + +P+ I+ +V +
Sbjct: 194 TSPIFEINSTILTKLLTALNECTEWGQVFILDALSRYKASDPREAENIVERVTPRLQHAN 253
Query: 287 AISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQ--SLDPNLRYISCVLFYHIGKI 344
+V+ ++ I++ L + C LV S +P ++Y++ + I
Sbjct: 254 C-AVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPEIQYVA------LRNI 306
Query: 345 NF-----EFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVD 399
N I+ ++ V + I ++ + LE+ +AS NI ++
Sbjct: 307 NLIVQKRPTILAHEIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVL----------- 355
Query: 400 TVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNN 459
+ + ++D+ V+ A + C I + + + +L +L + +
Sbjct: 356 -LEFKEYATEVDVDF---VRKAVRAIGRCAIK----LERAAERCISVLLELIKIKVNYVV 407
Query: 460 LEVSTLLGDNFRNIMVKVPSMRDAALEQLIK-LTTNDDIIAKLPNLLKEGIWCFGEYSEL 518
E ++ D FR + P+ ++ + L + L T D+ P IW GEY+E
Sbjct: 408 QEAIIVIKDIFR----RYPNTYESIIATLCESLDTLDE-----PEAKASMIWIIGEYAER 458
Query: 519 IDNCDTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFME 578
IDN D L+ L + P V ++ A VKLF TEG + +
Sbjct: 459 IDNADELLESFLENFPEEPAQVQLQLLTATVKLF-LKKPTEGPQQ-------MIQVVLNN 510
Query: 579 QKYRSTNFDIQERSVEFYEMLKLCQDALQDETEGLPLLITD----VLPSLFNE 627
+ N D+++R+ ++ +L +A +D +ITD + PSL +E
Sbjct: 511 ATVETDNPDLRDRAYIYWRLLSTDPEAAKDVVLAEKPVITDDSNQLDPSLLDE 563
>7292916 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 568
Score = 90.9 bits (224), Expect = 8e-18
Identities = 87/388 (22%), Positives = 178/388 (45%), Gaps = 47/388 (12%)
Query: 288 ISVIYESINCIVKGQMLEEDDYD----TAHQCLNHLESLVQSLDPNLRYISCVLFYHIGK 343
+S++YE IN ++ + + C+ L L++ D NL+Y+ + I K
Sbjct: 1 MSLLYECINTVIAVLISISSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILK 60
Query: 344 INFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHV 403
+ + + + L++ L D D SIR + L+L G+ S N+ +V+ L+ +
Sbjct: 61 THPKSVQAHKDLILACLDDKDESIRLRALDLLYGMVSKKNLMEIVKRLLGHMERAEGSAY 120
Query: 404 NDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVS 463
D+ L YK V+++C + Y + +F+WYL +L +L + +
Sbjct: 121 RDE-------LLYK------VIEICAQSSYLYVT-NFEWYLTVLVELIQLEAGSRH---G 163
Query: 464 TLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAK---LPNLLKEGIWCFGEYSELID 520
L+ + ++ ++VP +R A+ ++ L + A+ + +L W GE++ ++
Sbjct: 164 RLIAEQLLDVAIRVPVVRQFAVNEMTNLLDTFTVSAQSNSMYEVLYAAAWIVGEFAGELE 223
Query: 521 NCDTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDL--LSTLIAFME 578
+ + + ILL + LP + + ++KLF+ A T E+ DL L TL +
Sbjct: 224 DAEKTLNILL-RPRLLPGHIQGVYVQNVIKLFARLAT----TCLELQDLPGLVTLCDHVL 278
Query: 579 QKYR----STNFDIQERSVEFYEMLKLCQDALQDETE----------GLPLLITDVLP-- 622
K + S++ ++QER+ ++++ ++ L T+ G+P L +++
Sbjct: 279 DKLQHFNGSSDIEVQERANSACMLIEMLRNQLSTSTDAMAMDTTTEGGIPPLAIEIVQEM 338
Query: 623 SLFNEYELGPMSHGQQQQLVKALTLDLD 650
+L EL P++ Q+++ LDLD
Sbjct: 339 TLLFTGELIPVAPKAQRKVPLPDGLDLD 366
>At4g11380 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 894
Score = 89.7 bits (221), Expect = 2e-17
Identities = 125/593 (21%), Positives = 240/593 (40%), Gaps = 63/593 (10%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E +EE+ S + + +AV K+ G D++ V+ M + N + K++ YL
Sbjct: 17 IPELKEELNSQYKDKRKDAVKKVIAAMTVGKDVSSLFTDVVNCMQTENLELKKLVYLYLI 76
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ +LA N KD + N ++ +A+ + I ++ +CD L L
Sbjct: 77 NYAKSQPDLAILAVNTFVKDSQDP--NPLIR-ALAVRTMGCIRVDKITEYLCDPLQKCLK 133
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVSVICELAKHN 229
PYVRK A + K+F E + D L + D + VV+ AV+ + E+ +++
Sbjct: 134 DDDPYVRKTAAICVAKLFDINAELVEDRGFLEALKDLISDNNPMVVANAVAALAEIQENS 193
Query: 230 PGPFIQFSPLLYEMLIQIDNN---WIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKTT 286
P + + L+ N W + +L + +P+ I+ +V +
Sbjct: 194 SSPIFEINSTTLTKLLTALNECTEWGQVFILDALSKYKAADPREAENIVERVTPRLQHAN 253
Query: 287 AISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQ--SLDPNLRYISCVLFYHIGKI 344
+V+ ++ I++ L + C LV S +P ++Y++ + I
Sbjct: 254 C-AVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPEIQYVA------LRNI 306
Query: 345 NF-----EFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVD 399
N I+ ++ V + I ++ + LE+ +AS NI ++
Sbjct: 307 NLIVQKRPTILAHEIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVL----------- 355
Query: 400 TVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNN 459
+ + ++D+ V+ A + C I + + + +L +L + +
Sbjct: 356 -LEFKEYATEVDVDF---VRKAVRAIGRCAIK----LERAAERCISVLLELIKIKVNYVV 407
Query: 460 LEVSTLLGDNFRNIMVKVPSMRDAALEQLIK-LTTNDDIIAKLPNLLKEGIWCFGEYSEL 518
E ++ D FR + P+ ++ + L + L T D+ P IW GEY+E
Sbjct: 408 QEAIIVIKDIFR----RYPNTYESIIATLCESLDTLDE-----PEAKASMIWIIGEYAER 458
Query: 519 IDNCDTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFME 578
IDN D L+ L + P V ++ A VKLF TEG + +
Sbjct: 459 IDNADELLESFLENFPEEPAQVQLQLLTATVKLF-LKKPTEGPQQ-------MIQVVLNN 510
Query: 579 QKYRSTNFDIQERSVEFYEMLKLCQDALQDETEGLPLLITD----VLPSLFNE 627
+ N D+++R+ ++ +L +A +D +I+D + PSL +E
Sbjct: 511 ATVETDNPDLRDRAYIYWRLLSTDPEAAKDVVLAEKPVISDDSNQLDPSLLDE 563
>Hs4557469 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 937
Score = 85.9 bits (211), Expect = 3e-16
Identities = 120/557 (21%), Positives = 227/557 (40%), Gaps = 50/557 (8%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E + E+ + + AV K+ G D++ V+ M ++N + K++ YL
Sbjct: 15 IFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLM 74
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ ++A N KD + N ++ +A+ + I ++ +C+ L L
Sbjct: 75 NYAKSQPDMAIMAVNSFVKDCEDP--NPLIR-ALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVSVICELAKHN 229
PYVRK A + K+ + + D L + D + VV+ AV+ + E+++ +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESH 191
Query: 230 PGP-FIQFSPLLYEMLIQIDNN---WIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKT 285
P + +P L+ N W I +L ++ + ++ + I +V +
Sbjct: 192 PNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHA 251
Query: 286 TAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSL---DPNLRYISCVLFYHIG 342
+ +V+ ++ ++K L D D + L L + +L +P ++Y++ I
Sbjct: 252 NS-AVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIV 310
Query: 343 KINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVH 402
+ E + Q K+ D I ++ + L++ +AS NI ++ L + +VD
Sbjct: 311 QKRPEILKQEIKVFFVKYND-PIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVD--- 366
Query: 403 VNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEV 462
+D V+ A + C I + + + L DL + E
Sbjct: 367 -------VDF-----VRKAVRAIGRCAIK----VEQSAERCVSTLLDLIQTKVNYVVQEA 410
Query: 463 STLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNC 522
++ D FR K S+ E L L D A IW GEY+E IDN
Sbjct: 411 IVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAM--------IWIVGEYAERIDNA 462
Query: 523 DTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYR 582
D L+ L + V T++ A+VKLF + SE +L+ +++ Q
Sbjct: 463 DELLESFLEGFHDESTQVQLTLLTAIVKLFL-------KKPSETQELVQQVLSLATQD-- 513
Query: 583 STNFDIQERSVEFYEML 599
S N D+++R ++ +L
Sbjct: 514 SDNPDLRDRGYIYWRLL 530
>HsM4501973 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 949
Score = 84.0 bits (206), Expect = 1e-15
Identities = 119/557 (21%), Positives = 225/557 (40%), Gaps = 50/557 (8%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E + E+ S K AV K+ G D++ V+ M ++N + K++ YL
Sbjct: 15 IFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLM 74
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ ++A N KD + N ++ +A+ + I ++ +C+ L L
Sbjct: 75 NYAKSQPDMAIMAVNTFVKDCEDP--NPLIR-ALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVSVICELAKHN 229
PYVRK A + K+ + + D L + D + VV+ AV+ + E+A+ +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESH 191
Query: 230 PGP-FIQFSPLLYEMLIQIDNN---WIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKT 285
P + +P L+ N W I +L + ++ + I +V +
Sbjct: 192 PSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSHA 251
Query: 286 TAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSL---DPNLRYISCVLFYHIG 342
+ +V+ ++ ++K + D D L L + +L +P L+Y++ I
Sbjct: 252 NS-AVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIV 310
Query: 343 KINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVH 402
+ E I++++ V + + I ++ + L++ +AS NI ++ L + +VD
Sbjct: 311 QKRPE-ILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVD--- 366
Query: 403 VNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEV 462
+D V+ A + C I + + + L DL + E
Sbjct: 367 -------VDF-----VRKAVRAIGRCAIK----VEQSAERCVSTLLDLIQTKVNYVVQEA 410
Query: 463 STLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNC 522
++ D FR K S+ E L L P IW GEY+E IDN
Sbjct: 411 IVVIKDIFRKYPNKYESVIATLCENLDSLDE--------PEARAAMIWIVGEYAERIDNA 462
Query: 523 DTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYR 582
D L+ L + V ++ A+VKLF + +E +L+ +++ Q
Sbjct: 463 DELLESFLEGFHDESTQVQLQLLTAIVKLFL-------KKPTETQELVQQVLSLATQD-- 513
Query: 583 STNFDIQERSVEFYEML 599
S N D+++R ++ +L
Sbjct: 514 SDNPDLRDRGYIYWRLL 530
>Hs22027653 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 942
Score = 84.0 bits (206), Expect = 1e-15
Identities = 119/557 (21%), Positives = 225/557 (40%), Gaps = 50/557 (8%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E + E+ S K AV K+ G D++ V+ M ++N + K++ YL
Sbjct: 15 IFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLM 74
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ ++A N KD + N ++ +A+ + I ++ +C+ L L
Sbjct: 75 NYAKSQPDMAIMAVNTFVKDCEDP--NPLIR-ALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVSVICELAKHN 229
PYVRK A + K+ + + D L + D + VV+ AV+ + E+A+ +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESH 191
Query: 230 PGP-FIQFSPLLYEMLIQIDNN---WIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKT 285
P + +P L+ N W I +L + ++ + I +V +
Sbjct: 192 PSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSHA 251
Query: 286 TAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSL---DPNLRYISCVLFYHIG 342
+ +V+ ++ ++K + D D L L + +L +P L+Y++ I
Sbjct: 252 NS-AVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIV 310
Query: 343 KINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVH 402
+ E I++++ V + + I ++ + L++ +AS NI ++ L + +VD
Sbjct: 311 QKRPE-ILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVD--- 366
Query: 403 VNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEV 462
+D V+ A + C I + + + L DL + E
Sbjct: 367 -------VDF-----VRKAVRAIGRCAIK----VEQSAERCVSTLLDLIQTKVNYVVQEA 410
Query: 463 STLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNC 522
++ D FR K S+ E L L P IW GEY+E IDN
Sbjct: 411 IVVIKDIFRKYPNKYESVIATLCENLDSLDE--------PEARAAMIWIVGEYAERIDNA 462
Query: 523 DTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYR 582
D L+ L + V ++ A+VKLF + +E +L+ +++ Q
Sbjct: 463 DELLESFLEGFHDESTQVQLQLLTAIVKLFL-------KKPTETQELVQQVLSLATQD-- 513
Query: 583 STNFDIQERSVEFYEML 599
S N D+++R ++ +L
Sbjct: 514 SDNPDLRDRGYIYWRLL 530
>Hs22027651 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 949
Score = 84.0 bits (206), Expect = 1e-15
Identities = 119/557 (21%), Positives = 225/557 (40%), Gaps = 50/557 (8%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E + E+ S K AV K+ G D++ V+ M ++N + K++ YL
Sbjct: 15 IFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLM 74
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ ++A N KD + N ++ +A+ + I ++ +C+ L L
Sbjct: 75 NYAKSQPDMAIMAVNTFVKDCEDP--NPLIR-ALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVSVICELAKHN 229
PYVRK A + K+ + + D L + D + VV+ AV+ + E+A+ +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESH 191
Query: 230 PGP-FIQFSPLLYEMLIQIDNN---WIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKT 285
P + +P L+ N W I +L + ++ + I +V +
Sbjct: 192 PSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSHA 251
Query: 286 TAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSL---DPNLRYISCVLFYHIG 342
+ +V+ ++ ++K + D D L L + +L +P L+Y++ I
Sbjct: 252 NS-AVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIV 310
Query: 343 KINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVH 402
+ E I++++ V + + I ++ + L++ +AS NI ++ L + +VD
Sbjct: 311 QKRPE-ILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVD--- 366
Query: 403 VNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEV 462
+D V+ A + C I + + + L DL + E
Sbjct: 367 -------VDF-----VRKAVRAIGRCAIK----VEQSAERCVSTLLDLIQTKVNYVVQEA 410
Query: 463 STLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNC 522
++ D FR K S+ E L L P IW GEY+E IDN
Sbjct: 411 IVVIKDIFRKYPNKYESVIATLCENLDSLDE--------PEARAAMIWIVGEYAERIDNA 462
Query: 523 DTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYR 582
D L+ L + V ++ A+VKLF + +E +L+ +++ Q
Sbjct: 463 DELLESFLEGFHDESTQVQLQLLTAIVKLFL-------KKPTETQELVQQVLSLATQD-- 513
Query: 583 STNFDIQERSVEFYEML 599
S N D+++R ++ +L
Sbjct: 514 SDNPDLRDRGYIYWRLL 530
>YPR029c [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 832
Score = 82.0 bits (201), Expect = 4e-15
Identities = 138/636 (21%), Positives = 244/636 (37%), Gaps = 148/636 (23%)
Query: 26 SLKDLIKGIRSNNETPEQLQDFLNQAIVECREEVKS---PDFNMKTNAVLKLTYLEMYGF 82
SL+ IK +R ++ Q+ + R +++ P + N + KL YL + G
Sbjct: 4 SLRSFIKDVRGAKTLADERAIITKQS-AKIRTKLRDDHLPHEKRRVN-IQKLLYLYILGE 61
Query: 83 DMAWANFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVK 142
+ + +++S++F KR+GYLAA+ + D+L L TN+L DL +
Sbjct: 62 KTHFGQVESINLIASDDFVDKRLGYLAATLLLDESEDLLTLLTNMLNNDLHHP---NKYA 118
Query: 143 MGVALSGLSTIVTPELARDICDDL-FLMLNSGKPYVRKKAVTALFKVFLQYPESLRD--- 198
+ +AL+ L + +PELARD+ D+ ++ NS P++ KKA+ K+ + L
Sbjct: 119 VSLALTSLGFLSSPELARDLYPDVENIIKNSRDPFLLKKALQCAAKLIFKDVSLLEIFNI 178
Query: 199 -------------------GLSKFVSTL----------EDEDTSVVSAAVSVICELAKHN 229
G++K + ++ EDED + + ++ L
Sbjct: 179 EDITKILSSHSICTHGVLLGVTKIIQSILLIGLNRKKDEDEDEDGIDYSNDILSPL---- 234
Query: 230 PGPFIQFSPLLYEMLIQIDN--------------------NWIIIRLLKLF---TSLSKE 266
S LL + I+++N II LKL+ L
Sbjct: 235 -------SLLLRDFFIRLENMNSKNIEPGYDVQGICDPFLQCEIIYTLKLYFQVGELLNS 287
Query: 267 EPKLRYK-----ILPKVLELMD--KTTAISVIYESINCIVKGQMLEEDDYDTAHQCLNHL 319
L YK +L ++ D K + +++YE++ I + + +N L
Sbjct: 288 NNVLDYKDNFCDLLTRIATNTDSTKNSGQAILYETVKTIFSLDL----NQPLRVLGINIL 343
Query: 320 ESLVQSLDPNLRYISCVLFYHIGKINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIA 379
+ D N +Y+S + + ++ K + L+D D+SIR + LEL I
Sbjct: 344 AKFLAGKDNNTKYVSLNTLLKVVPQEPTAVQRHRKFISHCLQDTDVSIRMRALELSFAIL 403
Query: 380 STDNIKNLVRILIKQFVDVDTVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGD 439
N+ LV L+K D D I +++ + T + D
Sbjct: 404 DDSNLVELVNELMKFLAKQD----EDSKDLIIYTIDHLIDTFDT-----------RVVKD 448
Query: 440 FDWYLKILTD-LCIVSQDLNNLEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLT------ 492
W L + + L +V +N +++ +L I++ S E L K+
Sbjct: 449 ESWKLDVFFNILKLVGSFINYEKINDIL------IIINNTSQLSDKSEFLRKMLTISLNG 502
Query: 493 TNDDIIAKLPNLLKEGIWCFGEYSELIDNCDTLVGILLNKANKLPDTVIQTMIPALVKLF 552
T+ +I + IWC GEY +L+ LN+ NK +I
Sbjct: 503 TSAEISEENIGWQLVLIWCIGEYGDLV----------LNEGNKNGADII----------- 541
Query: 553 STYANTEGRTKSEISDLLSTLIAFMEQKYRSTNFDI 588
+S I+D L TL ++ Y +TN I
Sbjct: 542 ---------NESSITDYLLTL----QELYTATNLKI 564
>7293642 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 921
Score = 82.0 bits (201), Expect = 4e-15
Identities = 124/591 (20%), Positives = 246/591 (40%), Gaps = 57/591 (9%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E + E+ + K AV K+ G D++ V+ M ++N + K++ YL
Sbjct: 15 IFELKSELNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLM 74
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ ++A N KD + SN ++ +A+ + I ++ +C+ L L
Sbjct: 75 NYAKSQPDMAIMAVNTFVKDCED--SNPLIR-ALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDG--LSKFVSTLEDEDTSVVSAAVSVICEL--AK 227
PYVRK A + K++ + D L + L D + VV+ AV+ + E+ A
Sbjct: 132 DEDPYVRKTAAVCVAKLYDISATMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEINEAS 191
Query: 228 HNPGPFIQFSPLLYEMLIQIDNN---WIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDK 284
+ P ++ + + L+ N W + +L + S ++ + I ++ +
Sbjct: 192 QSGQPLVEMNSVTINKLLTALNECTEWGQVFILDSLANYSPKDEREAQSICERITPRLAH 251
Query: 285 TTAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSL---DPNLRYISCVLFYHI 341
A +V+ ++ ++K + D D L + +L +P ++Y++ I
Sbjct: 252 ANA-AVVLSAVKVLMKLLEMLSSDSDFCATLTKKLAPPLVTLLSSEPEVQYVALRNINLI 310
Query: 342 GKINFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTV 401
+ + I++++ V + + I ++ + L++ +A+ NI ++ L + +VD
Sbjct: 311 VQKRPD-ILKHEMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQVLSELKEYATEVD-- 367
Query: 402 HVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLE 461
+D V+ A + C I + + + L DL + E
Sbjct: 368 --------VDF-----VRKAVRAIGRCAIK----VEPSAERCVSTLLDLIQTKVNYVVQE 410
Query: 462 VSTLLGDNFRNIMVKVPSMRDAALEQLIK-LTTNDDIIAKLPNLLKEGIWCFGEYSELID 520
++ D FR K P+ ++ + L + L T D+ P +W GEY+E ID
Sbjct: 411 AIVVIKDIFR----KYPNKYESIISTLCENLDTLDE-----PEARASMVWIIGEYAERID 461
Query: 521 NCDTLVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQK 580
N D L+ L V ++ A+VKLF + S+ +L+ +++ Q
Sbjct: 462 NADELLDSFLEGFQDENAQVQLQLLTAVVKLFL-------KRPSDTQELVQHVLSLATQD 514
Query: 581 YRSTNFDIQERSVEFYEMLKLCQDALQDETEGLPLLI---TDVL-PSLFNE 627
S N D+++R ++ +L A ++ LI TD+L P+L +E
Sbjct: 515 --SDNPDLRDRGFIYWRLLSTDPAAAKEVVLADKPLISEETDLLEPTLLDE 563
>At1g23940_3 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 361
Score = 70.5 bits (171), Expect = 1e-11
Identities = 54/219 (24%), Positives = 104/219 (46%), Gaps = 13/219 (5%)
Query: 28 KDLIKGIRSNNETPEQLQDFLNQAIVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWA 87
+D+I+ +R+ E+ + + + R + D + + + KL + M G+ +
Sbjct: 1 RDMIRAVRACQTAAEE-RAVVRKECANIRALINEDDPHDRHRNLAKLMLIHMLGYPTHFV 59
Query: 88 NFHVLEVMSSNNFQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVAL 147
L++++S F +KR+GYL +LML T LK+DL + SN+ V +G+AL
Sbjct: 60 QMECLKLIASPGFPEKRIGYLGL---------MLMLVTKSLKQDLNH--SNQYV-VGLAL 107
Query: 148 SGLSTIVTPELARDICDDLFLMLNSGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVSTL 207
L I + E+A D+ ++ ++ P +RKKA ++ + P+ + + ++ S L
Sbjct: 108 FALGNICSAEMAPDLAPEVERLVQFRDPNIRKKAALCSTRIVRKVPDLVENFVNADASLL 167
Query: 208 EDEDTSVVSAAVSVICELAKHNPGPFIQFSPLLYEMLIQ 246
+++ V+ V + EL N F E LI+
Sbjct: 168 KEKHHGVLIRGVQLCYELCTINDEALEYFRTKCTEGLIK 206
>CE24628 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 827
Score = 70.1 bits (170), Expect = 1e-11
Identities = 112/555 (20%), Positives = 227/555 (40%), Gaps = 49/555 (8%)
Query: 52 IVECREEVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLEVMSSNNFQQKRVGYLAAS 111
I E + E+ S K AV K+ G D++ V+ M ++N + K++ YL
Sbjct: 15 IFELKNELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNVELKKLVYLYLM 74
Query: 112 QSFYKDSDILMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
D+ ++A N KD + N ++ +A+ + I ++ +CD L +
Sbjct: 75 NYAKSQPDLAIMAVNTFVKDCEDP--NPLIR-ALAVRTMGCIRVEKITEYLCDPLRRCMK 131
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRD-GLSKFVSTL-EDEDTSVVSAAVSVICELAKHN 229
PYVRK A + K+ P +++ G + ++ L D + VV+ AV+ + E+ +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDMNPALVKEQGFVELLNDLLSDANPMVVANAVAALTEMNEQQ 191
Query: 230 PGPFIQFSPLLYEMLIQIDN--NWIIIRLLKLFTSLSKEEPKLRYKILPKVLELMDKTTA 287
+ S ++ ++L ++ W + +L + + + I ++ + A
Sbjct: 192 TVIEVN-SQMVNKLLTALNECTEWGQVFILDALAGYTPRDERETQNICERISPRLAHANA 250
Query: 288 ISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSL---DPNLRYISCVLFYHIGKI 344
+V+ ++ ++K + D D Q L + +L +P ++Y++ I +
Sbjct: 251 -AVVLSTVKVLMKLIDMMPADSDFITQLTKKLAPPMVTLLSAEPEIQYVALRNINLIVQK 309
Query: 345 NFEFIMQYDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVN 404
+ + Q K+ D I ++ + L++ +A +NI ++ L + +VD
Sbjct: 310 RPDILKQEMKVFFVKYND-PIYVKMEKLDIMIRLAQQNNIAQVLSELKEYATEVD----- 363
Query: 405 DQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVST 464
+D V+ + + C I + + ++ L +L + E
Sbjct: 364 -----VDF-----VRKSVRAIGRCAIK----VEASSERCVQTLLELIQTKVNYVVQEAVV 409
Query: 465 LLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSELIDNCDT 524
++ D FR + S+ A E L L P IW GEY+E IDN D
Sbjct: 410 VIKDIFRKYPNRYESIISALCENLDTLDE--------PEARASMIWIIGEYAERIDNADE 461
Query: 525 LVGILLNKANKLPDTVIQTMIPALVKLFSTYANTEGRTKSEISDLLSTLIAFMEQKYRST 584
L+ + + V ++ A+VKLF G ++ + +LS +A + S
Sbjct: 462 LLESFVEGFHDENTQVQLQLLTAVVKLF---LKRPGVAQALVQRVLS--LATQD----SD 512
Query: 585 NFDIQERSVEFYEML 599
N D+++R ++ +L
Sbjct: 513 NPDLRDRGFIYWRLL 527
>YDR238c [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 973
Score = 68.2 bits (165), Expect = 6e-11
Identities = 103/478 (21%), Positives = 203/478 (41%), Gaps = 60/478 (12%)
Query: 58 EVKSPDFNMKTNAVLKLTYLEMYGFDMAWANFHVLE-VMSSNNFQQKRVGYL--AASQSF 114
E S + + T + +T LE G M H++ VM S N + K++ Y
Sbjct: 33 EKGSDEQKIDTMKSILVTMLE--GNPMPELLMHIIRFVMPSKNKELKKLLYFYWEIVPKL 90
Query: 115 YKDSDI---LMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLN 171
+D + ++L N ++ DL++ NE ++ G L L+ + EL + + L
Sbjct: 91 AEDGKLRHEMILVCNAIQHDLQHP--NEYIR-GNTLRFLTKLREAELLEQMVPSVLACLE 147
Query: 172 SGKPYVRKKAVTALFKVFLQYPESLRDGLSKFVSTLEDEDTSVVSAAVSV-ICELAKHNP 230
YVRK A+ A+F +F L D S + E + + + EL + N
Sbjct: 148 YRHAYVRKYAILAVFSIFKVSEHLLPDAKEIINSFIVAETDPICKRNAFIGLAELDRENA 207
Query: 231 GPFIQ--------FSPLLYEMLIQIDNNWIIIRLLKLFTSLSKEEPKLRYKILPKVLELM 282
+++ PLL + +Q + P L+ + + ++EL+
Sbjct: 208 LHYLENNIADIENLDPLLQAVFVQ------------FIRQDANRTPALKAQYIELLMELL 255
Query: 283 DKTTAISVIYESINCIVKGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYISCVLFYHIG 342
TT+ VI+E+ + + + + +N L L + N I ++ I
Sbjct: 256 STTTSDEVIFETALALT----VLSANPNVLVPAVNKLIDLAVKVSDN--NIKLIVLDRIQ 309
Query: 343 KINFEFIMQYDKLVIGLLKDV---DISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVD 399
IN + ++L + +L+ + D+ +R+K L++ +A++ N +++V++L K+
Sbjct: 310 DINANNVGALEELTLDILRVLNAEDLDVRSKALDISMDLATSRNAEDVVQLLKKEL--QT 367
Query: 400 TVHVNDQGVQIDIPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNN 459
TV+ DQ D + Y+ + KT+ V +N E +++ L DLN+
Sbjct: 368 TVNNPDQ----DKAMQYRQLLIKTIRTV-AVNFVE-------MAASVVSLLLDFIGDLNS 415
Query: 460 LEVSTLLGDNFRNIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSE 517
+ S ++ + ++ K P +R LE +++ T D + + + +W GEY+E
Sbjct: 416 VAASGIIA-FIKEVIEKYPQLRANILENMVQ--TLDKV--RSAKAYRGALWIMGEYAE 468
>7293454 [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 963
Score = 57.0 bits (136), Expect = 1e-07
Identities = 91/406 (22%), Positives = 166/406 (40%), Gaps = 46/406 (11%)
Query: 121 LMLATNLLKKDLKYDLSNETVKMGVALSGLSTIVTPELARDICDDLFLMLNSGKPYVRKK 180
++L + +KDL++ NE ++ G L L + PEL + + L+ YVR+
Sbjct: 96 MILVCDAYRKDLQHP--NEFLR-GSTLRFLCKLKEPELLEPLMPAIRACLDHRHSYVRRN 152
Query: 181 AVTALFKVFLQYPESLRDGLSKFVSTLE-DEDTSVVSAAVSVICELAKHNPGPFIQFSPL 239
AV A+F ++ + + DG S L+ +D S A ++ + +
Sbjct: 153 AVLAIFTIYKNFDWLVPDGPELIASFLDTQQDMSCKRNAFLMLLHADQERALNY------ 206
Query: 240 LYEMLIQIDNNWIIIRL--LKLFTSLSKEEPKLRYKILPKVLELMDKTTAISVIYESINC 297
L + Q+ I++L ++L + P R + + + L++ +++ +V YES
Sbjct: 207 LASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLN-SSSNAVRYESAGT 265
Query: 298 IVKGQMLEEDDYDTAHQCLNHLESLVQSLDPNLRYI----SCVLFYHIG--KINFEFIMQ 351
++ L A C ++E +V+ D N++ I + H G K+ + +M
Sbjct: 266 LIT-LSLAPTAIKAAASC--YIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMD 322
Query: 352 YDKLVIGLLKDVDISIRTKVLELCSGIASTDNIKNLVRILIKQFVDVDTVHVNDQGVQID 411
V+ +L DI +R K L L + + NI +V +L K+ V D G
Sbjct: 323 ----VLRVLAAPDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNVEHEDTG---- 374
Query: 412 IPLNYKVKVAKTVLDVCCINDYENINGDFDWYLKILTDLCIVSQDLNNLEVSTLLGDNFR 471
Y+ + +T L C I D ++ L D N L + +L R
Sbjct: 375 ---KYRQLLVRT-LHTCSIKFP-------DVAANVIPVLVEFLSDTNELAAADVL-IFIR 422
Query: 472 NIMVKVPSMRDAALEQLIKLTTNDDIIAKLPNLLKEGIWCFGEYSE 517
+ K P++R +E LI+ K + + +W GEY E
Sbjct: 423 EAIQKFPALRALIIEHLIEAFPQ----IKSSKIHRAAVWILGEYVE 464
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,967,693
Number of Sequences: 60738
Number of extensions: 1916704
Number of successful extensions: 5700
Number of sequences better than 1.0e-05: 36
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 5591
Number of HSP's gapped (non-prelim): 52
length of query: 908
length of database: 30,389,216
effective HSP length: 116
effective length of query: 792
effective length of database: 23,343,608
effective search space: 18488137536
effective search space used: 18488137536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)