ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5131 good U KOG3875 Intracellular trafficking, secretion, and vesicular transport Peroxisomal biogenesis protein peroxin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5131 1757908 1756685 -408
(408 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR191w [U] KOG3875 Peroxisomal biogenesis protein peroxin 300 3e-81
SPAC3C7.10 [U] KOG3875 Peroxisomal biogenesis protein peroxin 118 1e-26
Hs4505723 [U] KOG3875 Peroxisomal biogenesis protein peroxin 79 9e-15
7303343 [U] KOG3875 Peroxisomal biogenesis protein peroxin 66 8e-11
Hs4885153 [T] KOG4792 Crk family adapters 54 4e-07
Hs5453754 [T] KOG4226 Adaptor protein NCK/Dock contains SH2 and ... 50 6e-06
>YLR191w [U] KOG3875 Peroxisomal biogenesis protein peroxin
Length = 386
Score = 300 bits (768), Expect = 3e-81
Identities = 153/244 (62%), Positives = 189/244 (76%), Gaps = 2/244 (0%)
Query: 143 IAESTQATFQLIEGLIGAVAGFAQMLEATYMATHNSFFTMITVAEQFQYMKELLGSFFGI 202
+ EST+ATFQLIE LIGAV GFAQMLE+TYMATHNSFFTMI+VAEQF +KE+LGSFFGI
Sbjct: 141 LGESTKATFQLIESLIGAVTGFAQMLESTYMATHNSFFTMISVAEQFGNLKEMLGSFFGI 200
Query: 203 FALIKFVKKILYRVTGGKMGVAPSKKRLGIEGGKSQGSDLSKQFIEEFRDSDLTKKKGRR 262
FA++KF+KKILYR T G++G+ P K EG K++ + ++F + + K R+
Sbjct: 201 FAIMKFLKKILYRATKGRLGI-PPKNFAESEGSKNKLIEDFQKFNDSGTINSNEKATRRK 259
Query: 263 ISWKPLIVFLAAVFGFPYLLNKFIQKLQQHQKAKIAGGAMAQQILDPNNLEFARAIYDFV 322
ISWKPL+ FL AVFGFPYLLNKFI KLQ + + G ++ I DP+ LEFARA+YDFV
Sbjct: 260 ISWKPLLFFLMAVFGFPYLLNKFITKLQTSGTIRASQGNGSEPI-DPSKLEFARALYDFV 318
Query: 323 PENPRIECNLKKGDLMAIISKKDPLGNNSEWWKVRTKQGNIGYVPYNYLELIKKRKNGVP 382
PENP +E LKKGDLMAI+SKKDPLG +S+WWKVRTK GNIGY+PYNY+E+IK+RK
Sbjct: 319 PENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEIIKRRKKIEH 378
Query: 383 VESE 386
V+ E
Sbjct: 379 VDDE 382
>SPAC3C7.10 [U] KOG3875 Peroxisomal biogenesis protein peroxin
Length = 288
Score = 118 bits (296), Expect = 1e-26
Identities = 68/228 (29%), Positives = 122/228 (52%), Gaps = 22/228 (9%)
Query: 149 ATFQLIEGLIGAVAGFAQMLEATYMATHNSFFTMITVAEQFQYMKELLGSFFGIFALIKF 208
++ Q+IE ++GAV AQ+LE+T MA H S+ T ++V+E +K +G+ FGI +L+
Sbjct: 83 SSLQVIESIVGAVGSIAQVLESTLMAAHMSYNTFVSVSENLNKLKSSIGAIFGIVSLLSR 142
Query: 209 VKKILYRVTGGKMGVAPSKKRLGIEGGKSQGSDLSKQFIEEFRDSDLTKKKGRRISWKPL 268
+K+++ + S+ +++ Q + F + K L
Sbjct: 143 LKRLVLKFFK-----------------HSKIDEMNSQEYDVFEKEEGNHKNSIYSIVSSL 185
Query: 269 IVFLAAVFGFPYLLNKFIQKLQQHQKAKIAGGAMAQQILDPNNLEFARAIYDFVPENPRI 328
+ L V G PY + + + + + +K +I + ++I ++LEF +A Y+F+ +P +
Sbjct: 186 AIILGLV-GLPYAIIRLFKNIYEKEK-QIQQAKIRKKI---DSLEFCKADYEFMSRDPGV 240
Query: 329 ECNLKKGDLMAIISKKDPLGNNSEWWKVRTKQGNIGYVPYNYLELIKK 376
E +LKKGD++AI+SK D GN EWW+ R + G G+ P NY +I +
Sbjct: 241 EMSLKKGDIIAILSKTDTQGNPCEWWQGRKRSGETGWFPSNYCSIISR 288
>Hs4505723 [U] KOG3875 Peroxisomal biogenesis protein peroxin
Length = 403
Score = 79.3 bits (194), Expect = 9e-15
Identities = 66/253 (26%), Positives = 116/253 (45%), Gaps = 27/253 (10%)
Query: 145 ESTQATFQLIEGLIGAVAGFAQMLEATYMATHNSFFTMITVAEQFQYMKELLGSFFGIFA 204
ES++ FQ IE ++ A A + M++AT+ A +NSF ++ VA F +K F FA
Sbjct: 124 ESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFA 183
Query: 205 LIKFVKKILYRVTGGKMGVAPSKKRLGIEGGKSQGSDL---SKQFIEEFRDSDLTKKKGR 261
L++ ++ + R+ ++ LG+ G S+ DL S+ + D +
Sbjct: 184 LVRTIRYLYRRL----------QRMLGLRRG-SENEDLWAESEGTVACLGAEDRAATSAK 232
Query: 262 RISWKPLIVFLAAVFGFPYLLNKFIQKLQQHQKAKIAGGAMAQQILDPNNLEFARAIYDF 321
SW P+ +F A + G PYL+ K + I + ++ ARA YDF
Sbjct: 233 --SW-PIFLFFAVILGGPYLIWKLLSTHSDEVTDSINWAS------GEDDHVVARAEYDF 283
Query: 322 VPENPRIECNLKKGDLMAIISKKDPLGNNSEWWKVRTKQG-NIGYVPYNYLELIKKRKNG 380
+ E + + GD++ + K+ W + + G G +P NY++++ KRK
Sbjct: 284 AAVSEE-EISFRAGDMLNLALKEQQ--PKVRGWLLASLDGQTTGLIPANYVKILGKRKGR 340
Query: 381 VPVESEKSNTSEE 393
VES K + ++
Sbjct: 341 KTVESSKVSKQQQ 353
>7303343 [U] KOG3875 Peroxisomal biogenesis protein peroxin
Length = 440
Score = 66.2 bits (160), Expect = 8e-11
Identities = 58/258 (22%), Positives = 118/258 (45%), Gaps = 27/258 (10%)
Query: 146 STQATFQLIEGLIGAVAGFAQMLEATYMATHNSFFTMITVAEQFQYMKELLGSFFGIFAL 205
S++ FQ IE L+ A+ A ML++T+ A +SF ++ VA F ++ + F+ FA+
Sbjct: 155 SSRPAFQSIESLVSAIGNIASMLDSTFFALTSSFRAILGVATNFVRLRSVFAQFWTTFAI 214
Query: 206 IK----FVKKILY--RVTGGKMGVAPSKKRLGIEGGKSQGSDLSKQFIEEFRDSDLTKKK 259
+ +KILY R++ A KK ++ G + R + +K
Sbjct: 215 FRGLNWMYRKILYWLRLSNLDPSSAAFKKAFAEALNENNG---------QARGAPNVPRK 265
Query: 260 GRRISWKPLIVFLAAVFGFPYLLNKFIQKLQQHQKAKIAGGAMAQQILDPNNLEFARAIY 319
G W P++ F++ +F PYL+ K + + + + A + +A+Y
Sbjct: 266 GNS-PW-PVLAFISFIFTAPYLIMKLLGTVTNTAQEEARNPAKWTAPIQ------TQAVY 317
Query: 320 DFVPENPRIECNLKKGDLMAIISK--KDPLGNNSEWWKVRTKQGNI-GYVPYNYLELIKK 376
+FV +P E +L+ G ++ + + + L + W + T G G +P +Y++ ++
Sbjct: 318 EFVARSPS-ELSLRAGQMLHVAPRDIQQTLNLLNTGWALATTNGQTSGIIPISYVKSPQQ 376
Query: 377 RKNGVPVESEKSNTSEEL 394
+ + +++ + EL
Sbjct: 377 MRQEMQDQTKPAQPQPEL 394
>Hs4885153 [T] KOG4792 Crk family adapters
Length = 303
Score = 53.9 bits (128), Expect = 4e-07
Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 7/72 (9%)
Query: 310 NNLEFARAIYDFVPENPRIECNLKKGDLMAIISKKDPLGNNSEWWKVRTKQGNIGYVPYN 369
+NLE+ R +YDF P N + KKG+++ II K + +WW R K G +G +P
Sbjct: 123 DNLEYVRTLYDF-PGNDAEDLPFKKGEILVIIEKPE-----EQWWSARNKDGRVGMIPVP 176
Query: 370 YLE-LIKKRKNG 380
Y+E L++ +G
Sbjct: 177 YVEKLVRSSPHG 188
>Hs5453754 [T] KOG4226 Adaptor protein NCK/Dock contains SH2 and SH3 domains
Length = 377
Score = 50.1 bits (118), Expect = 6e-06
Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 4/64 (6%)
Query: 312 LEFARAIYDFVPENPRIECNLKKGDLMAIISKKDPLGNNSEWWKVRTKQGNIGYVPYNYL 371
L +A+Y F N E N +KGD+M +I K + N+ EWWK R G +G VP NY+
Sbjct: 192 LHVVQALYPFSSSNDE-ELNFEKGDVMDVIEKPE---NDPEWWKCRKINGMVGLVPKNYV 247
Query: 372 ELIK 375
+++
Sbjct: 248 TVMQ 251
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.134 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,882,621
Number of Sequences: 60738
Number of extensions: 820476
Number of successful extensions: 1898
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1887
Number of HSP's gapped (non-prelim): 8
length of query: 408
length of database: 30,389,216
effective HSP length: 109
effective length of query: 299
effective length of database: 23,768,774
effective search space: 7106863426
effective search space used: 7106863426
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)