ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5144 good E KOG1250 Amino acid transport and metabolism Threonine/serine dehydratases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5144 1762503 1760803 -567
(567 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER086w [E] KOG1250 Threonine/serine dehydratases 869 0.0
SPBC1677.03c [E] KOG1250 Threonine/serine dehydratases 555 e-158
At3g10050 [E] KOG1250 Threonine/serine dehydratases 417 e-116
YKL218c [TE] KOG1251 Serine racemase 170 5e-42
7299166 [E] KOG1250 Threonine/serine dehydratases 167 5e-41
SPCC320.14 [TE] KOG1251 Serine racemase 162 1e-39
CE02261 [E] KOG1250 Threonine/serine dehydratases 156 9e-38
CE26153 [E] KOG1250 Threonine/serine dehydratases 154 3e-37
At4g11640 [TE] KOG1251 Serine racemase 135 1e-31
Hs11345492 [TE] KOG1251 Serine racemase 123 8e-28
Hs5803161 [E] KOG1250 Threonine/serine dehydratases 114 5e-25
Hs19923959 [E] KOG1250 Threonine/serine dehydratases 113 7e-25
CE13016 [TE] KOG1251 Serine racemase 113 9e-25
YCL064c [E] KOG1250 Threonine/serine dehydratases 78 4e-14
>YER086w [E] KOG1250 Threonine/serine dehydratases
Length = 576
Score = 869 bits (2246), Expect = 0.0
Identities = 432/568 (76%), Positives = 494/568 (86%), Gaps = 3/568 (0%)
Query: 2 LQSIVRTPRVLRAS--NALKLSVRCVSTDQFSDNLQRMYSHLKADERLEDGSPDYVRLIL 59
L ++VR + + S N L+L + S +L +++S LK DE D +PDYVRL+L
Sbjct: 10 LCTVVRQGKQSKVSGLNLLRLKAH-LHRQHLSPSLIKLHSELKLDELQTDNTPDYVRLVL 68
Query: 60 RSSVYEVIEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAG 119
RSSVY+VI E+PIS+ V LSSRLNTNV LKREDLLPVFSFKLRGAYNMIAKLD++Q+N G
Sbjct: 69 RSSVYDVINESPISQGVGLSSRLNTNVILKREDLLPVFSFKLRGAYNMIAKLDDSQRNQG 128
Query: 120 VIACSAGNHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLE 179
VIACSAGNHAQGVAF++ H+ IPATIVMPV TPSIKYQNVSRLG+QVVLYG+DFDEAK E
Sbjct: 129 VIACSAGNHAQGVAFAAKHLKIPATIVMPVCTPSIKYQNVSRLGSQVVLYGNDFDEAKAE 188
Query: 180 CARLAEERGMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXX 239
CA+LAEERG+T+IPPFDHPYVIAGQGT+AMEILRQV+ + IGAVF V
Sbjct: 189 CAKLAEERGLTNIPPFDHPYVIAGQGTVAMEILRQVRTANKIGAVFVPVGGGGLIAGIGA 248
Query: 240 YLKRIAPHIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQDV 299
YLKR+APHIK+IGVETYDAATL SL+ +RTPLP VGTFADGTSVR+IGEETFRV Q V
Sbjct: 249 YLKRVAPHIKIIGVETYDAATLHNSLQRNQRTPLPVVGTFADGTSVRMIGEETFRVAQQV 308
Query: 300 VDEVILVNTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSKKTYVPIL 359
VDEV+LVNTDEICAAVKD+FEDTRSIVEPSGAL+VAG+KKY+S +HPEIDH+K TYVPIL
Sbjct: 309 VDEVVLVNTDEICAAVKDIFEDTRSIVEPSGALSVAGMKKYISTVHPEIDHTKNTYVPIL 368
Query: 360 SGANMNFDRLRFVSERAVLGEGKEVFMLVTIPDTPGSFKKLQNVIHPRAVTEFSYRYNEH 419
SGANMNFDRLRFVSERAVLGEGKEVFMLVT+PD PG+FKK+Q +IHPR+VTEFSYRYNEH
Sbjct: 369 SGANMNFDRLRFVSERAVLGEGKEVFMLVTLPDVPGAFKKMQKIIHPRSVTEFSYRYNEH 428
Query: 420 CHENDSDVPTACIYTSFNVVDREKEIKQVVQQLHALGFEAVDISDNEMAKSHGRYLVGGA 479
HE+ S+VP A IYTSF+VVDREKEIKQV+QQL+ALGFEAVDISDNE+AKSHGRYLVGGA
Sbjct: 429 RHESSSEVPKAYIYTSFSVVDREKEIKQVMQQLNALGFEAVDISDNELAKSHGRYLVGGA 488
Query: 480 SKIENEKVIAFEFPERPGALTKFLSGLNVSWNLTLFHYRNHGADIGKILAGISVPPQDNE 539
SK+ NE++I+FEFPERPGALT+FL GL+ SWNLTLFHYRNHGADIGK+LAGISVPP++N
Sbjct: 489 SKVPNERIISFEFPERPGALTRFLGGLSDSWNLTLFHYRNHGADIGKVLAGISVPPRENL 548
Query: 540 IFQKFLDDLGYKYQDETDNMVYQKFLKY 567
FQKFL+DLGY Y DETDN VYQKFLKY
Sbjct: 549 TFQKFLEDLGYTYHDETDNTVYQKFLKY 576
>SPBC1677.03c [E] KOG1250 Threonine/serine dehydratases
Length = 600
Score = 555 bits (1429), Expect = e-158
Identities = 285/520 (54%), Positives = 373/520 (70%), Gaps = 11/520 (2%)
Query: 47 LEDGSPDYVRLILRSSVYEVIEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYN 106
L DG+PDY+RL L S+VYEVI+ETP+++ V +S V LKREDL PVFSFK+RGA+N
Sbjct: 91 LPDGTPDYLRLTLTSNVYEVIKETPLTKGVVISESTGVPVYLKREDLTPVFSFKIRGAHN 150
Query: 107 MIAKLDETQKNAGVIACSAGNHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQV 166
+A LD+ GVIACSAGNHAQGVA+S+ + + ATIVMP +TP IK++NV RLGA V
Sbjct: 151 KMASLDKQSLKNGVIACSAGNHAQGVAYSARTLGVKATIVMPQNTPEIKWRNVKRLGANV 210
Query: 167 VLYGDDFDEAKLECARLAEERGMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFC 226
+L+G +FD AK ECARLA+E+ + I PFD PYVIAGQGTI +EIL Q+ + + A++C
Sbjct: 211 LLHGANFDIAKAECARLAKEQNLEVIHPFDDPYVIAGQGTIGLEILHQI-DLRKLDAIYC 269
Query: 227 AVXXXXXXXXXXXYLKRIAPHIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVR 286
AV Y+KRIAPH+KVIGVET+DA L SLK+ KR L VG FADGT+V+
Sbjct: 270 AVGGGGLIAGIATYVKRIAPHVKVIGVETFDADALKKSLKDKKRVTLKEVGLFADGTAVK 329
Query: 287 LIGEETFRVCQDVVDEVILVNTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHP 346
L+GEETFR+ +D+V+LV+ DEICAA+KDVF DTRS+VEPSGA+AVAG+K+YV++ P
Sbjct: 330 LVGEETFRLVSKNIDDVVLVDKDEICAAIKDVFLDTRSVVEPSGAMAVAGMKRYVAKHKP 389
Query: 347 EIDHSKKTYVPILSGANMNFDRLRFVSERAVLGEGKEVFMLVTIPDTPGSFKKLQNVIHP 406
+ + V ILSGANM+FDRLRF++ERA LG KEVF+ VTIP+ PGSF+ L N+I P
Sbjct: 390 K--NPNAAQVCILSGANMDFDRLRFIAERADLGLNKEVFLSVTIPERPGSFEALHNIITP 447
Query: 407 RAVTEFSYRYNEHCHENDSDVPTACIYTSFNVVDREKEIKQVVQQLHALGFEAVDISDNE 466
R++TEFSYRY+ + N IYTSF V DR E+ ++QQ+ A DISDNE
Sbjct: 448 RSITEFSYRYDNDDYAN--------IYTSFVVKDRATELPLILQQISEQNMVAEDISDNE 499
Query: 467 MAKSHGRYLVGGASKIENEKVIAFEFPERPGALTKFLSGLNVSWNLTLFHYRNHGADIGK 526
+AK+H RYL+GG S + E++ +FPERPGAL KFL + +++LFHYRN G DI
Sbjct: 500 LAKTHARYLIGGKSSVSKERLYRLDFPERPGALCKFLRSIKEVCSISLFHYRNCGGDIAS 559
Query: 527 ILAGISVPPQDNEIFQKFLDDLGYKYQDETDNMVYQKFLK 566
+LAG+ V E L+++GY + DET+N VY ++L+
Sbjct: 560 VLAGLRVFDGQVEKLHSVLEEIGYNWVDETNNPVYLRYLR 599
>At3g10050 [E] KOG1250 Threonine/serine dehydratases
Length = 592
Score = 417 bits (1073), Expect = e-116
Identities = 224/500 (44%), Positives = 312/500 (61%), Gaps = 15/500 (3%)
Query: 53 DYVRLILRSSVYEVIEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLD 112
+Y+ IL + VY++ E+P+ A LS RL + LKREDL PVFSFKLRGAYNM+ KL
Sbjct: 94 EYLTNILSTKVYDIAIESPLQLAKKLSKRLGVRMYLKREDLQPVFSFKLRGAYNMMVKLP 153
Query: 113 ETQKNAGVIACSAGNHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDD 172
Q GVI SAGNHAQGVA S++ + A IVMPV+TP IK+Q V LGA VVL+GD
Sbjct: 154 ADQLAKGVICSSAGNHAQGVALSASKLGCTAVIVMPVTTPEIKWQAVENLGATVVLFGDS 213
Query: 173 FDEAKLECARLAEERGMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXX 232
+D+A+ AEE G+T IPPFDHP VIAGQGT+ MEI RQ + + A+F V
Sbjct: 214 YDQAQAHAKIRAEEEGLTFIPPFDHPDVIAGQGTVGMEITRQAK--GPLHAIFVPVGGGG 271
Query: 233 XXXXXXXYLKRIAPHIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEET 292
Y+KR++P +K+IGVE DA + +SL +G+R L VG FADG +V+ +GEET
Sbjct: 272 LIAGIAAYVKRVSPEVKIIGVEPADANAMALSLHHGERVILDQVGGFADGVAVKEVGEET 331
Query: 293 FRVCQDVVDEVILVNTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSK 352
FR+ ++++D V+LV D ICA++KD+FE+ R+I+EP+GALA+AG + Y
Sbjct: 332 FRISRNLMDGVVLVTRDAICASIKDMFEEKRNILEPAGALALAGAEAYCKY----YGLKD 387
Query: 353 KTYVPILSGANMNFDRLRFVSERAVLGEGKEVFMLVTIPDTPGSFKKLQNVIHPRAVTEF 412
V I SGANMNFD+LR V+E A +G +E + +P+ PGSFK+ ++ P ++EF
Sbjct: 388 VNVVAITSGANMNFDKLRIVTELANVGRQQEAVLATLMPEKPGSFKQFCELVGPMNISEF 447
Query: 413 SYRYNEHCHENDSDVPTACIYTSFNVVDREKEIKQVVQQLHALGFEAVDISDNEMAKSHG 472
YR + S+ +Y+ V E+K + +++ + + V+++ +++ K H
Sbjct: 448 KYRCS-------SEKEAVVLYSV--GVHTAGELKALQKRMESSQLKTVNLTTSDLVKDHL 498
Query: 473 RYLVGGASKIENEKVIAFEFPERPGALTKFLSGLNVSWNLTLFHYRNHGADIGKILAGIS 532
RYL+GG S + +E + F FPERPGAL FL + WN+TLFHYR G +L GI
Sbjct: 499 RYLMGGRSTVGDEVLCRFTFPERPGALMNFLDSFSPRWNITLFHYRGQGETGANVLVGIQ 558
Query: 533 VPPQDNEIFQKFLDDLGYKY 552
VP Q+ E F+ LGY Y
Sbjct: 559 VPEQEMEEFKNRAKALGYDY 578
>YKL218c [TE] KOG1251 Serine racemase
Length = 326
Score = 170 bits (431), Expect = 5e-42
Identities = 106/321 (33%), Positives = 168/321 (52%), Gaps = 15/321 (4%)
Query: 63 VYEVIEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAGVIA 122
+ E + +TP+ + L+ RL + K E+ V +FK RGA N ++KL + +++ GVIA
Sbjct: 16 IKEYVNKTPVLTSRMLNDRLGAQIYFKGENFQRVGAFKFRGAMNAVSKLSDEKRSKGVIA 75
Query: 123 CSAGNHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLECAR 182
S+GNHAQ +A S+ +N+PATIVMP P++K + GA ++ Y ++ + +
Sbjct: 76 FSSGNHAQAIALSAKLLNVPATIVMPEDAPALKVAATAGYGAHIIRYNRYTEDREQIGRQ 135
Query: 183 LAEERGMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXXYLK 242
LA E G IPP+DHP VIAGQGT A E+L +V + A+F + +
Sbjct: 136 LAAEHGFALIPPYDHPDVIAGQGTSAKELLEEV---GQLDALFVPLGGGGLLSGSALAAR 192
Query: 243 RIAPHIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQDVVDE 302
++P K+ GVE S ++G + + T ADG + +GE TF + ++ VD+
Sbjct: 193 SLSPGCKIFGVEPEAGNDGQQSFRSGSIVHINTPKTIADGAQTQHLGEYTFAIIRENVDD 252
Query: 303 VILVNTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSKKTYVPILSGA 362
++ V+ E+ + + E + +VEP+ L AG + L E KK + ILSG
Sbjct: 253 ILTVSDQELVKCMHFLAERMKVVVEPTACLGFAG-----ALLKKEELVGKKVGI-ILSGG 306
Query: 363 NMNFDRLRFVSERAVLGEGKE 383
N++ R A L GKE
Sbjct: 307 NVDMKRY------ATLISGKE 321
>7299166 [E] KOG1250 Threonine/serine dehydratases
Length = 469
Score = 167 bits (422), Expect = 5e-41
Identities = 106/335 (31%), Positives = 166/335 (48%), Gaps = 11/335 (3%)
Query: 67 IEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAGVIACSAG 126
+E TP ++ S S + LK++ L SFK RGA + L E QK GVI+ S G
Sbjct: 75 VERTPCPKSTS-SDLYGMELYLKKDFLQYTGSFKERGARYALLSLTEEQKRTGVISASLG 133
Query: 127 NHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLECARLAEE 186
NHAQ + + +NIP T+VMP + P +K Q A+V++ G+D EAK R++ E
Sbjct: 134 NHAQALCYHGWKLNIPVTVVMPKAAPIMKIQKCRNYKARVIVDGNDMGEAKSLAMRMSRE 193
Query: 187 RGMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXXYLKRIAP 246
G+ + +DHP+++AGQGTI +EIL QV AV V +K ++P
Sbjct: 194 EGLLYVNGYDHPHIMAGQGTIGLEILEQVPEPD---AVVVPVGGGGLIAGIATAVKALSP 250
Query: 247 HIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQDVVDEVILV 306
K+IGVE+ A+ +++N P T ADG +V +G + ++D +++V
Sbjct: 251 KTKIIGVESEKCASFTRAMENDGPIHTPIKNTLADGLAVPKVGYNAYATAMPLIDRMVVV 310
Query: 307 NTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSK-KTYVPILSGANMN 365
+ I A+ + E+ + +VE +G +A + L +D K K V +L G N++
Sbjct: 311 KEEWIAVAILRLVEEEKCVVEGAGGAGLAAI------LAGHLDELKGKKVVVLLCGGNID 364
Query: 366 FDRLRFVSERAVLGEGKEVFMLVTIPDTPGSFKKL 400
ER + G+ V V + D PG L
Sbjct: 365 TTVFGRCLERGLAAVGRLVKFNVEVSDRPGGINDL 399
>SPCC320.14 [TE] KOG1251 Serine racemase
Length = 323
Score = 162 bits (410), Expect = 1e-39
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 9/300 (3%)
Query: 69 ETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAGVIACSAGNH 128
+TP+ + +++ V K E+ + +FK RGA N +++L+E Q+ AGV+ S+GNH
Sbjct: 26 KTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQLNEAQRKAGVLTFSSGNH 85
Query: 129 AQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLECARLAEERG 188
AQ +A S+ + IPA I+MP+ P K G QV++Y D+ + ++E G
Sbjct: 86 AQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYKDDREKMAKEISEREG 145
Query: 189 MTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXXYLKRIAPHI 248
+T IPP+DHP+V+AGQGT A E+ +V + A+F + + AP+
Sbjct: 146 LTIIPPYDHPHVLAGQGTAAKELFEEV---GPLDALFVCLGGGGLLSGSALAARHFAPNC 202
Query: 249 KVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQDVVDEVILVNT 308
+V GVE S + G + + T ADG + +G TF + ++ VD+++ V+
Sbjct: 203 EVYGVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVDDILTVSD 262
Query: 309 DEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSKKTYVPILSGANMNFDR 368
+E+ +K + +VEP+G L+ A + +L K I+SG N++ +R
Sbjct: 263 EELIDCLKFYAARMKIVVEPTGCLSFAAARAMKEKL------KNKRIGIIISGGNVDIER 316
>CE02261 [E] KOG1250 Threonine/serine dehydratases
Length = 512
Score = 156 bits (394), Expect = 9e-38
Identities = 112/348 (32%), Positives = 170/348 (48%), Gaps = 15/348 (4%)
Query: 67 IEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAGVIACSAG 126
++ TP R++ LSS+ ++ K+E L SFK RGA ++K+ E K AGVIA SAG
Sbjct: 115 VQTTPCVRSLQLSSKCEMDLYFKKEYLQVTGSFKERGARYALSKMAEQFKKAGVIAASAG 174
Query: 127 NHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLECARLAEE 186
NHA +++ M IP T+VMPV P +K Q LGA V+L G+ AK R A+E
Sbjct: 175 NHALALSYHGQQMGIPVTVVMPVIAPLMKIQFCRSLGATVILKGESIAVAKDFALRHAKE 234
Query: 187 RGMTDIPPFDHPYVIAGQGTIAMEILRQVQN----------GSNIGAVFCAVXXXXXXXX 236
+ I +D ++AGQGTI +EIL QV + G I + AV
Sbjct: 235 NHLKYINGYDAIDILAGQGTIGLEILDQVPDVDTILVPVGGGGLIAGIATAVKTLKPDVH 294
Query: 237 XXXYLKRIAPHIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVC 296
I + KV G+E+ + + + G + + ADG +V +G +
Sbjct: 295 IYVSSFLIIANFKVTGIESETCPSFTEAYEAGHIITSQAKASLADGLAVPTVGGNSLETA 354
Query: 297 QDVVDEVILVNTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSKKTYV 356
+ +VD+VI V + I ++ + E +++VE GA+ GL + PE+ K V
Sbjct: 355 KGLVDKVITVKEESIALSILRLLEVEKAVVEGGGAV---GLAAILEGKVPEL--KGKKVV 409
Query: 357 PILSGANMNFDRLRFVSERAVLGEGKEVFMLVTIPDTPGSFKKLQNVI 404
ILSG N++ L ER + +G+ V + V + D PG +L I
Sbjct: 410 SILSGGNIDTTVLGRSIERGLAVDGRLVRLEVVVSDRPGGIAELTTTI 457
>CE26153 [E] KOG1250 Threonine/serine dehydratases
Length = 448
Score = 154 bits (389), Expect = 3e-37
Identities = 111/388 (28%), Positives = 177/388 (45%), Gaps = 10/388 (2%)
Query: 67 IEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAGVIACSAG 126
I T ++ LS + N+ LK E SFK RGA + L E +K AGV A SAG
Sbjct: 55 IVRTDCRKSRCLSKLFDMNIYLKMEVNQDTGSFKERGARYALQNLPEEKKKAGVYAASAG 114
Query: 127 NHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLECARLAEE 186
NHA ++ + + +VMP P +K LGA +++ G+D E++ R+A +
Sbjct: 115 NHALALSLHGKQLGVEVNVVMPKIAPLMKINRCQDLGANILVQGEDIAESREIALRMAHD 174
Query: 187 RGMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXXYLKRIAP 246
T I +DH ++AG GT +EIL Q+Q A+ V +K ++P
Sbjct: 175 SNGTYINGYDHYDILAGAGTTGIEILEQIQMPD---AILVPVGGGGLVAGVATAVKALSP 231
Query: 247 HIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQDVVDEVILV 306
+VIGV + + SL+ G P+ T ADG +V G F VD VI V
Sbjct: 232 TTEVIGVVSETCQAIVKSLQAGHPVYTPTRPTLADGLAVPNAGVNAFASMIGKVDRVISV 291
Query: 307 NTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSK-KTYVPILSGANMN 365
++I A+ + E+ + + E +GA+ + + L +++H K KT V ILSG N++
Sbjct: 292 PENDIAVAILRLIENEKVVCEGAGAIGIGAI------LSGKLNHLKGKTVVSILSGGNID 345
Query: 366 FDRLRFVSERAVLGEGKEVFMLVTIPDTPGSFKKLQNVIHPRAVTEFSYRYNEHCHENDS 425
L ER + + + + + V IPD PG KL ++ + ND
Sbjct: 346 STSLGRCIERGLAYDHRVIRLSVIIPDKPGGLSKLTGLVGELSGNVRDLYLERAFMRNDM 405
Query: 426 DVPTACIYTSFNVVDREKEIKQVVQQLH 453
+ + E ++KQ Q+++
Sbjct: 406 SSQRVKMVIEVRGEEHEMQLKQKFQEVY 433
>At4g11640 [TE] KOG1251 Serine racemase
Length = 346
Score = 135 bits (341), Expect = 1e-31
Identities = 89/272 (32%), Positives = 135/272 (48%), Gaps = 5/272 (1%)
Query: 98 SFKLRGAYNMIAKLDETQKNAGVIACSAGNHAQGVAFSSNHMNIPATIVMPVSTPSIKYQ 157
+FK RGA N + LD Q GV+ S+GNHA ++ ++ IPA IV+P P K
Sbjct: 72 AFKFRGACNAVLSLDAEQAAKGVVTHSSGNHAAALSLAAKIQGIPAYIVVPKGAPKCKVD 131
Query: 158 NVSRLGAQVVLYGDDFDEAKLECARLAEERGMTDIPPFDHPYVIAGQGTIAMEILRQVQN 217
NV R G +V+ + +++ +E G I P++ +I+GQGTIA+E+L Q+Q
Sbjct: 132 NVIRYGGKVIWSEATMSSREEIASKVLQETGSVLIHPYNDGRIISGQGTIALELLEQIQ- 190
Query: 218 GSNIGAVFCAVXXXXXXXXXXXYLKRIAPHIKVIGVETYDAATLDVSLKNGKRTPLPSVG 277
I A+ + K I P I++I E A S GK LP
Sbjct: 191 --EIDAIVVPISGGGLISGVALAAKSIKPSIRIIAAEPKGADDAAQSKVAGKIITLPVTN 248
Query: 278 TFADGTSVRLIGEETFRVCQDVVDEVILVNTDEICAAVKDVFEDTRSIVEPSGALAVAGL 337
T ADG L G+ T+ V +D+VD+V+ + EI A+K +E + VEPSGA+ +A +
Sbjct: 249 TIADGLRASL-GDLTWPVVRDLVDDVVTLEECEIIEAMKMCYEILKVSVEPSGAIGLAAV 307
Query: 338 KKYVSQLHPEIDHSKKTYVPILSGANMNFDRL 369
+ +P K + +LSG N++ L
Sbjct: 308 LSNSFRNNPSCRDCKNIGI-VLSGGNVDLGSL 338
>Hs11345492 [TE] KOG1251 Serine racemase
Length = 340
Score = 123 bits (308), Expect = 8e-28
Identities = 97/310 (31%), Positives = 150/310 (48%), Gaps = 15/310 (4%)
Query: 62 SVYEVIEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDET---QKNA 118
++ + I TP+ + L+ N+ K E SFK+RGA N + L +K
Sbjct: 18 NIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPK 77
Query: 119 GVIACSAGNHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKL 178
V+ S+GNH Q + +++ IPA IV+P + P K + GA +V Y + DE++
Sbjct: 78 AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIV-YCEPSDESRE 136
Query: 179 ECA-RLAEERGMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXX 237
A R+ EE + P P VIAGQGTIA+E+L QV + A+ V
Sbjct: 137 NVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQV---PLVDALVVPVGGGGMLAGI 193
Query: 238 XXYLKRIAPHIKVIGVETYDAATLDVSLKNGKRTP-LPSVGTFADGTSVRLIGEETFRVC 296
+K + P +KV E +A S GK P L T ADG IG T+ +
Sbjct: 194 AITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVK-SSIGLNTWPII 252
Query: 297 QDVVDEVILVNTDEICAAVKDVFEDTRSIVEPSGALAVAG-LKKYVSQLHPEIDHSKKTY 355
+D+VD++ V DEI A + V+E + ++EP+ + VA L ++ + PE+ K
Sbjct: 253 RDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEV----KNI 308
Query: 356 VPILSGANMN 365
+LSG N++
Sbjct: 309 CIVLSGGNVD 318
>Hs5803161 [E] KOG1250 Threonine/serine dehydratases
Length = 328
Score = 114 bits (284), Expect = 5e-25
Identities = 86/316 (27%), Positives = 155/316 (48%), Gaps = 15/316 (4%)
Query: 69 ETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAGVIACSAGNH 128
+TPI +++LS T+V LK + P SFK+RG + + + Q A + SAGN
Sbjct: 10 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAK-QGCAHFVCSSAGNA 68
Query: 129 AQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEA-KLECARLAEER 187
A+++ + +PATIV+P +TP++ + + GA + G+ DEA +L A
Sbjct: 69 GMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATCKVVGELLDEAFELAKALAKNNP 128
Query: 188 GMTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXXYLKRIA-P 246
G IPPFD P + G +I E+ + GA+ +V L+
Sbjct: 129 GWVYIPPFDDPLIWEGHASIVKELKETL--WEKPGAIALSVGGGGLLCGVVQGLQECGWG 186
Query: 247 HIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQD--VVDEVI 304
+ VI +ET+ A + + GK LP + + A V+ +G + ++ Q+ + EVI
Sbjct: 187 DVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGSQALKLFQEHPIFSEVI 246
Query: 305 LVNTDEICAAVKDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSKKTYVP-----IL 359
+ E AA++ +D + +VEP+ A+A + +V Q +++ + +T +P +
Sbjct: 247 --SDQEAVAAIEKFVDDEKILVEPAWGAALAAVYSHVIQ-KLQLEGNLRTPLPSLVVIVC 303
Query: 360 SGANMNFDRLRFVSER 375
G+N++ +LR + E+
Sbjct: 304 GGSNISLAQLRALKEQ 319
>Hs19923959 [E] KOG1250 Threonine/serine dehydratases
Length = 329
Score = 113 bits (283), Expect = 7e-25
Identities = 77/270 (28%), Positives = 129/270 (47%), Gaps = 6/270 (2%)
Query: 70 TPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKLDETQKNAGVIACSAGNHA 129
TP+ + +LS V LK E++ P SFK+RG + ++ +K + CS+G +A
Sbjct: 18 TPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEM--AKKGCRHLVCSSGGNA 75
Query: 130 Q-GVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLECARLAEERG 188
A+++ + IPATIV+P ST Q + GA+V L G +DEA L LA+ G
Sbjct: 76 GIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELAKRDG 135
Query: 189 MTDIPPFDHPYVIAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXXYLKRIA-PH 247
++PPFDHP + G ++ E+ ++ GA+ AV L + H
Sbjct: 136 WENVPPFDHPLIWKGHASLVQELKAVLRTPP--GALVLAVGGGGLLAGVVAGLLEVGWQH 193
Query: 248 IKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQDVVDEVILVN 307
+ +I +ET+ A + ++ GK LP + + A + + Q +V
Sbjct: 194 VPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSEVVE 253
Query: 308 TDEICAAVKDVFEDTRSIVEPSGALAVAGL 337
E +AV+ + +D R +VEP+ A+A +
Sbjct: 254 DTEAVSAVQQLLDDERMLVEPACGAALAAI 283
>CE13016 [TE] KOG1251 Serine racemase
Length = 317
Score = 113 bits (282), Expect = 9e-25
Identities = 90/290 (31%), Positives = 146/290 (50%), Gaps = 26/290 (8%)
Query: 84 TNVKLKREDLLPVFSFKLRGAYN--MIAKLDETQKNA-GVIACSAGNHAQGVAFSSNHMN 140
T+V K E L SFK RGA N ++AK +KNA G+IA S+GNH Q +A+++ +
Sbjct: 40 THVLFKCEHLQKTGSFKARGALNSAILAK----EKNAKGMIAHSSGNHGQALAWAAQKIG 95
Query: 141 IPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEAKLECARLAEERGMTDIPPFDHPYV 200
+P TIV+P + P K + + A +V + CA L E+ + P++ +
Sbjct: 96 LPCTIVVPKNAPISKIEGMREYNANIVFCEPTVTSRESVCADLTEKLEYYCVEPYNCVSM 155
Query: 201 IAGQGTIAMEILRQVQNGSNIGAVFCAVXXXXXXXXXXXYLKRIAPHIKVIGVETYDAAT 260
I G ++A EIL QV G+ I ++F +V + + P I+V V+
Sbjct: 156 INGHSSVAFEILEQV--GNEIDSIFLSVGGGGLASSVAFLIGNLRPDIEVYLVQPAQ-KE 212
Query: 261 LDVSLKNGKRTPLPSVGTFADGTSVRLIGEETFRVCQDVV-----DEVILVNTDEICAAV 315
L L+NG + P+ ++ T ADG V +G +C+ ++ +VI V DEI +
Sbjct: 213 LSNFLENGIKCPVDTLDTIADGVRVARVGP----LCEPILKQYCAQKVISVKEDEIKEGL 268
Query: 316 KDVFEDTRSIVEPSGALAVAGLKKYVSQLHPEIDHSKKTYVPILSGANMN 365
K ++ + +EP+ ALA AG+ L+ + H K+ V IL G N++
Sbjct: 269 KLIWTRMKQRIEPTAALAFAGV------LYHKPAHIKRPLV-ILCGGNVD 311
>YCL064c [E] KOG1250 Threonine/serine dehydratases
Length = 360
Score = 77.8 bits (190), Expect = 4e-14
Identities = 65/286 (22%), Positives = 121/286 (41%), Gaps = 18/286 (6%)
Query: 66 VIEETPISRAVSLSSRLNTNVKLKREDLLPVFSFKLRGAYNMIAKL-----DETQKNAGV 120
V +TP+ R + + LK E L P SFK RG N+I K + +++ V
Sbjct: 4 VYNKTPLLRQF-FPGKASAQFFLKYECLQPSGSFKSRGIGNLIMKSAIRIQKDGKRSPQV 62
Query: 121 IACSAGNHAQGVAFSSNHMNIPATIVMPVSTPSIKYQNVSRLGAQVVLYGDDFDEA---- 176
A S GN A + +++P T+V+P +T + GAQV++ G + EA
Sbjct: 63 FASSGGNAGFAAATACQRLSLPCTVVVPTATKKRMVDKIRNTGAQVIVSGAYWKEADTFL 122
Query: 177 KLECARLAEERGMTDI--PPFDHPYVIAGQGTIAMEILRQVQNG----SNIGAVFCAVXX 230
K + + + I PFD+P + G ++ EI++ +++ + + + C+V
Sbjct: 123 KTNVMNKIDSQVIEPIYVHPFDNPDIWEGHSSMIDEIVQDLKSQHISVNKVKGIVCSVGG 182
Query: 231 XXXXXXXXXYLKR--IAPHIKVIGVETYDAATLDVSLKNGKRTPLPSVGTFADGTSVRLI 288
L+R +A I ++GVET + SLK G+ + + A +I
Sbjct: 183 GGLYNGIIQGLERYGLADRIPIVGVETNGCHVFNTSLKIGQPVQFKKITSIATSLGTAVI 242
Query: 289 GEETFRVCQDVVDEVILVNTDEICAAVKDVFEDTRSIVEPSGALAV 334
+TF + +++ ++ ++EP+ A+
Sbjct: 243 SNQTFEYARKYNTRSVVIEDKDVIETCLKYTHQFNMVIEPACGAAL 288
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,012,051
Number of Sequences: 60738
Number of extensions: 1408934
Number of successful extensions: 3258
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3212
Number of HSP's gapped (non-prelim): 16
length of query: 567
length of database: 30,389,216
effective HSP length: 112
effective length of query: 455
effective length of database: 23,586,560
effective search space: 10731884800
effective search space used: 10731884800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)