ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5173 good Q KOG0023 Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase, class V
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5173 1770061 1771158 366
(366 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR318c [Q] KOG0023 Alcohol dehydrogenase class V 424 e-119
YCR105w [Q] KOG0023 Alcohol dehydrogenase class V 375 e-104
At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V 181 1e-45
At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V 177 2e-44
At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V 177 3e-44
At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V 177 3e-44
At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V 171 2e-42
At4g37970 [Q] KOG0023 Alcohol dehydrogenase class V 168 1e-41
At3g19450 [Q] KOG0023 Alcohol dehydrogenase class V 166 7e-41
At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V 162 9e-40
At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V 156 5e-38
YOL086c [Q] KOG0023 Alcohol dehydrogenase class V 108 2e-23
YMR303c [Q] KOG0023 Alcohol dehydrogenase class V 107 2e-23
YBR145w [Q] KOG0023 Alcohol dehydrogenase class V 107 3e-23
CE12214 [Q] KOG0023 Alcohol dehydrogenase class V 99 8e-21
CE20628 [Q] KOG0023 Alcohol dehydrogenase class V 98 2e-20
YMR083w [Q] KOG0023 Alcohol dehydrogenase class V 96 6e-20
SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V 93 5e-19
CE12212 [Q] KOG0023 Alcohol dehydrogenase class V 92 1e-18
At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III 75 1e-13
7298873 [Q] KOG0024 Sorbitol dehydrogenase 71 2e-12
YAL060w [Q] KOG0024 Sorbitol dehydrogenase 69 8e-12
Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III 68 2e-11
7299382 [Q] KOG0024 Sorbitol dehydrogenase 68 2e-11
Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III 66 7e-11
Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III 62 1e-09
Hs4501931 [Q] KOG0022 Alcohol dehydrogenase class III 59 1e-08
At5g51970 [Q] KOG0024 Sorbitol dehydrogenase 58 2e-08
YDL246c [Q] KOG0024 Sorbitol dehydrogenase 57 3e-08
YJR159w [Q] KOG0024 Sorbitol dehydrogenase 57 4e-08
Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III 57 4e-08
CE06216 [Q] KOG0024 Sorbitol dehydrogenase 57 6e-08
SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase 56 7e-08
CE23822 [Q] KOG0022 Alcohol dehydrogenase class III 55 2e-07
7299380 [Q] KOG0022 Alcohol dehydrogenase class III 55 2e-07
CE06215 [Q] KOG0024 Sorbitol dehydrogenase 54 3e-07
YDL168w [Q] KOG0022 Alcohol dehydrogenase class III 53 6e-07
Hs11496891 [Q] KOG0022 Alcohol dehydrogenase class III 52 1e-06
CE22292_2 [Q] KOG0022 Alcohol dehydrogenase class III 52 1e-06
SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III 52 2e-06
SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III 50 7e-06
SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase 50 7e-06
>YMR318c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 424 bits (1091), Expect = e-119
Identities = 204/353 (57%), Positives = 256/353 (71%), Gaps = 3/353 (0%)
Query: 1 MSYPDNFEGFAVVDSHKKWLSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGE 60
MSYP+ FEG A+ SH+ W +P+K Y K F D+DI+IEACGVCGSD+HCA G+WG
Sbjct: 1 MSYPEKFEGIAI-QSHEDWKNPKKTKYDPKPFYDHDIDIKIEACGVCGSDIHCAAGHWGN 59
Query: 61 MKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVT 120
MK+PLVVGHEI+GKVV+LG K ++GLKVG RVGVGAQV +CL+C+RC NDNE YC KFVT
Sbjct: 60 MKMPLVVGHEIVGKVVKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVT 119
Query: 121 TYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXX 180
TYSQPY EDGYV QGGYA+++RVHEHFV+PIPE++ ++ APLLCGG TVYSPL RN
Sbjct: 120 TYSQPY-EDGYVSQGGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNGCG 178
Query: 181 XXXXXXXXXXXXXXXXXXLLAKAMGAEVYAISRSHAKEETSKQLGADHYIATEDEG-WET 239
L++KAMGAE Y ISRS K E + ++GADHYIAT +EG W
Sbjct: 179 PGKKVGIVGLGGIGSMGTLISKAMGAETYVISRSSRKREDAMKMGADHYIATLEEGDWGE 238
Query: 240 KYFDTLDFMVLCGNSLSAVDFGKLPKILKAQGVIASISVPDQHEAIHLHPAQLLGFQITQ 299
KYFDT D +V+C +SL+ +DF +PK +K G I SIS+P+QHE + L P L I+
Sbjct: 239 KYFDTFDLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYGLKAVSISY 298
Query: 300 SCLASRAEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGDVRFRFTL 352
S L S E+ ++L LV+EK IK+WVET+P+ E + F+RME GDVR+RFTL
Sbjct: 299 SALGSIKELNQLLKLVSEKDIKIWVETLPVGEAGVHEAFERMEKGDVRYRFTL 351
>YCR105w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 361
Score = 375 bits (963), Expect = e-104
Identities = 186/354 (52%), Positives = 241/354 (67%), Gaps = 4/354 (1%)
Query: 1 MSYPDNFEGFAVVDSHKKWLSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGE 60
M YP+ F+G + ++ K W P+ V + K F DVD+EIEACG+CGSD H A GNWG
Sbjct: 1 MLYPEKFQGIGISNA-KDWKHPKLVSFDPKPFGDHDVDVEIEACGICGSDFHIAVGNWGP 59
Query: 61 MKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPK-FV 119
+ ++GHEIIG+VV++G KC TG+K+GDRVGVGAQ AC +C RC +DNEQYC V
Sbjct: 60 VPENQILGHEIIGRVVKVGSKCHTGVKIGDRVGVGAQALACFECERCKSDNEQYCTNDHV 119
Query: 120 TTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXX 179
T PY +DGY+ QGG+ASH+R+HEHF I IPE++ + APLLCGG TV+SPL RN
Sbjct: 120 LTMWTPY-KDGYISQGGFASHVRLHEHFAIQIPENIPSPLAAPLLCGGITVFSPLLRNGC 178
Query: 180 XXXXXXXXXXXXXXXXXXXLLAKAMGAEVYAISRSHAKEETSKQLGADHYIA-TEDEGWE 238
LLAKAMGAEVYA SR H+K E S +LGADHYIA ED+GW
Sbjct: 179 GPGKRVGIVGIGGIGHMGILLAKAMGAEVYAFSRGHSKREDSMKLGADHYIAMLEDKGWT 238
Query: 239 TKYFDTLDFMVLCGNSLSAVDFGKLPKILKAQGVIASISVPDQHEAIHLHPAQLLGFQIT 298
+Y + LD +V+C +SLS V+F + KI+K G I SI+ P+ +E + L P L+G I+
Sbjct: 239 EQYSNALDLLVVCSSSLSKVNFDSIVKIMKIGGSIVSIAAPEVNEKLVLKPLGLMGVSIS 298
Query: 299 QSCLASRAEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGDVRFRFTL 352
S + SR EI ++L LV+EK +K+WVE +PISEE +S F RMESGDV++RFTL
Sbjct: 299 SSAIGSRKEIEQLLKLVSEKNVKIWVEKLPISEEGVSHAFTRMESGDVKYRFTL 352
>At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 181 bits (460), Expect = 1e-45
Identities = 120/336 (35%), Positives = 173/336 (50%), Gaps = 12/336 (3%)
Query: 20 LSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLG 79
LSP Y ++ P DV+I I CG+C +D+H K + G P+V GHE++G+VV +G
Sbjct: 22 LSP--YTYTLRETGPEDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGEVVEVG 79
Query: 80 DKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYAS 139
+ VGD VGVG V C C+ C D EQYCPK + +Y+ Y +G QGG+A
Sbjct: 80 SDV-SKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVYI-NGQPTQGGFAK 137
Query: 140 HIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKR-NXXXXXXXXXXXXXXXXXXXXX 198
VH+ FV+ IPE + APLLC G TVYSPL
Sbjct: 138 ATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGILGLGGVGHMGV 197
Query: 199 LLAKAMGAEVYAISRSHAK-EETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSA 257
+AKAMG V IS S+ K EE + LGAD Y+ D+ ++ D+LD+++ A
Sbjct: 198 KIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQAKMSELADSLDYVIDTVPVHHA 257
Query: 258 VDFGKLPKILKAQGVIASISVPDQHEAIHLHPAQLLGFQ-ITQSCLASRAEIIEMLNLVA 316
++ +LK G + + V + + L P +LG + IT S + S E EML
Sbjct: 258 LE--PYLSLLKLDGKLILMGVIN-NPLQFLTPLLMLGRKVITGSFIGSMKETEEMLEFCK 314
Query: 317 EKKIKLWVETVPISEENISTVFKRMESGDVRFRFTL 352
EK + +E V + + ++T F+R+E DVR+RF +
Sbjct: 315 EKGLSSIIEVVKM--DYVNTAFERLEKNDVRYRFVV 348
>At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 359
Score = 177 bits (450), Expect = 2e-44
Identities = 109/329 (33%), Positives = 168/329 (50%), Gaps = 10/329 (3%)
Query: 27 YPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGL 86
+ ++ +DV ++ CG+C SD+H K WG PLV GHEI+G V +G K T
Sbjct: 26 FTRRETGEKDVRFKVLFCGICHSDLHMVKNEWGMSTYPLVPGHEIVGVVTEVGAKV-TKF 84
Query: 87 KVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEH 146
K G++VGVG VS+C C+ C E YCPK + TY PY+ D + GGY+ H+ E
Sbjct: 85 KTGEKVGVGCLVSSCGSCDSCTEGMENYCPKSIQTYGFPYY-DNTITYGGYSDHMVCEEG 143
Query: 147 FVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXL-LAKAMG 205
FVI IP++L + APLLC G TVYSP+K + + AKAMG
Sbjct: 144 FVIRIPDNLPLDAAAPLLCAGITVYSPMKYHGLDKPGMHIGVVGLGGLGHVGVKFAKAMG 203
Query: 206 AEVYAISRSHAK-EETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSAV-DFGKL 263
+V IS S K +E +LGAD ++ + D T+D ++ +++SA L
Sbjct: 204 TKVTVISTSEKKRDEAINRLGADAFLVSRDPKQIKDAMGTMDGII---DTVSATHSLLPL 260
Query: 264 PKILKAQGVIASISVPDQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIKLW 323
+LK +G + + P++ + + P + S + E EM+++ + I
Sbjct: 261 LGLLKHKGKLVMVGAPEKPLELPVMPLIFERKMVMGSMIGGIKETQEMIDMAGKHNITAD 320
Query: 324 VETVPISEENISTVFKRMESGDVRFRFTL 352
+E IS + ++T +R+E DVR+RF +
Sbjct: 321 IEL--ISADYVNTAMERLEKADVRYRFVI 347
>At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 177 bits (448), Expect = 3e-44
Identities = 114/331 (34%), Positives = 170/331 (50%), Gaps = 13/331 (3%)
Query: 27 YPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGL 86
+ ++ DV ++I CGVC SD+H K +WG + P++ GHEI+G ++G K T
Sbjct: 24 FSRRENGENDVTVKILFCGVCHSDLHTIKNHWGFSRYPIIPGHEIVGIATKVG-KNVTKF 82
Query: 87 KVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEH 146
K GDRVGVG + +C C CN D E YCPK V TY+ DG QGGY+ I V
Sbjct: 83 KEGDRVGVGVIIGSCQSCESCNQDLENYCPKVVFTYNSRS-SDGTRNQGGYSDVIVVDHR 141
Query: 147 FVIPIPESLETNNVAPLLCGGATVYSPLK--RNXXXXXXXXXXXXXXXXXXXXXLLAKAM 204
FV+ IP+ L +++ APLLC G TVYSP+K + KA
Sbjct: 142 FVLSIPDGLPSDSGAPLLCAGITVYSPMKYYGMTKESGKRLGVNGLGGLGHIAVKIGKAF 201
Query: 205 GAEVYAISRSHAKE-ETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSAVDFGKL 263
G V ISRS KE E +LGAD ++ T D + T+DF++ +++SA + L
Sbjct: 202 GLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAVGTMDFII---DTVSA-EHALL 257
Query: 264 P--KILKAQGVIASISVPDQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIK 321
P +LK G + ++ + ++ + + P L + S + E EML A+ KI
Sbjct: 258 PLFSLLKVSGKLVALGLLEKPLDLPIFPLVLGRKMVGGSQIGGMKETQEMLEFCAKHKIV 317
Query: 322 LWVETVPISEENISTVFKRMESGDVRFRFTL 352
+E + +S+ I++ R+ DVR+RF +
Sbjct: 318 SDIELIKMSD--INSAMDRLVKSDVRYRFVI 346
>At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 376
Score = 177 bits (448), Expect = 3e-44
Identities = 112/331 (33%), Positives = 169/331 (50%), Gaps = 12/331 (3%)
Query: 27 YPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGL 86
+ ++ DV ++I CGVC SD+H K +WG + P++ GHEI+G ++G K T
Sbjct: 24 FSRRENGENDVTVKILFCGVCHSDLHTIKNHWGFSRYPIIPGHEIVGIATKVG-KNVTKF 82
Query: 87 KVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEH 146
K GDRVGVG + +C C CN D E YCPK V TY+ + QGGY+ I V
Sbjct: 83 KEGDRVGVGVIIGSCQSCESCNQDLENYCPKVVFTYNSRSSDGTSRNQGGYSDVIVVDHR 142
Query: 147 FVIPIPESLETNNVAPLLCGGATVYSPLK--RNXXXXXXXXXXXXXXXXXXXXXLLAKAM 204
FV+ IP+ L +++ APLLC G TVYSP+K + KA
Sbjct: 143 FVLSIPDGLPSDSGAPLLCAGITVYSPMKYYGMTKESGKRLGVNGLGGLGHIAVKIGKAF 202
Query: 205 GAEVYAISRSHAKE-ETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSAVDFGKL 263
G V ISRS KE E +LGAD ++ T D + T+DF++ +++SA + L
Sbjct: 203 GLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAVGTMDFII---DTVSA-EHALL 258
Query: 264 P--KILKAQGVIASISVPDQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIK 321
P +LK G + ++ +P++ + + L + S + E EML A+ KI
Sbjct: 259 PLFSLLKVNGKLVALGLPEKPLDLPIFSLVLGRKMVGGSQIGGMKETQEMLEFCAKHKIV 318
Query: 322 LWVETVPISEENISTVFKRMESGDVRFRFTL 352
+E + +S+ I++ R+ DVR+RF +
Sbjct: 319 SDIELIKMSD--INSAMDRLAKSDVRYRFVI 347
>At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 171 bits (432), Expect = 2e-42
Identities = 109/320 (34%), Positives = 164/320 (51%), Gaps = 10/320 (3%)
Query: 36 DVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVG 95
DV ++I CGVC +D+H K +WG P+V GHEI+G ++G K T K GDRVGVG
Sbjct: 39 DVTVKILFCGVCHTDLHTIKNDWGYSYYPVVPGHEIVGIATKVG-KNVTKFKEGDRVGVG 97
Query: 96 AQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPESL 155
+C C C+ D E YCP+ TY+ DG GGY+ +I V + FV+ PE+L
Sbjct: 98 VISGSCQSCESCDQDLENYCPQMSFTYNA-IGSDGTKNYGGYSENIVVDQRFVLRFPENL 156
Query: 156 ETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXL-LAKAMGAEVYAISRS 214
+++ APLLC G TVYSP+K + + KA G +V IS S
Sbjct: 157 PSDSGAPLLCAGITVYSPMKYYGMTEAGKHLGVAGLGGLGHVAVKIGKAFGLKVTVISSS 216
Query: 215 HAK-EETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSAVD-FGKLPKILKAQGV 272
K EE LGAD ++ T D T+D+++ +++SAV L +LK G
Sbjct: 217 STKAEEAINHLGADSFLVTTDPQKMKAAIGTMDYII---DTISAVHALYPLLGLLKVNGK 273
Query: 273 IASISVPDQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIKLWVETVPISEE 332
+ ++ +P++ + + P L + S + E EML+ A+ I +E + + E
Sbjct: 274 LIALGLPEKPLELPMFPLVLGRKMVGGSDVGGMKETQEMLDFCAKHNITADIELIKMDE- 332
Query: 333 NISTVFKRMESGDVRFRFTL 352
I+T +R+ DVR+RF +
Sbjct: 333 -INTAMERLAKSDVRYRFVI 351
>At4g37970 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 363
Score = 168 bits (425), Expect = 1e-41
Identities = 112/347 (32%), Positives = 171/347 (49%), Gaps = 13/347 (3%)
Query: 9 GFAVVDSHKKWLSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVG 68
G+A DS LSP V+ ++ +V +++ CG+C SD+HC K W PLV G
Sbjct: 16 GWAARDSSGH-LSP--FVFSRRKTGEEEVRVKVLYCGICHSDLHCLKNEWHSSIYPLVPG 72
Query: 69 HEIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFE 128
HEIIG+V +G+K + +GD+VGVG V +C C C D E YC K + TY+ +
Sbjct: 73 HEIIGEVSEIGNKV-SKFNLGDKVGVGCIVDSCRTCESCREDQENYCTKAIATYNGVH-H 130
Query: 129 DGYVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKR-NXXXXXXXXXX 187
DG + GGY+ HI V E + + IP +L + APLLC G ++YSP+K
Sbjct: 131 DGTINYGGYSDHIVVDERYAVKIPHTLPLVSAAPLLCAGISMYSPMKYFGLTGPDKHVGI 190
Query: 188 XXXXXXXXXXXLLAKAMGAEVYAISRSHAK-EETSKQLGADHYIATEDEGWETKYFDTLD 246
AKA G +V +S + K ++ LGAD ++ + DE T+D
Sbjct: 191 VGLGGLGHIGVRFAKAFGTKVTVVSSTTGKSKDALDTLGADGFLVSTDEDQMKAAMGTMD 250
Query: 247 FMVLCGNSLSAV-DFGKLPKILKAQGVIASISVPDQHEAIHLHPAQLLGFQITQSCLASR 305
++ +++SA L +LK+ G + + ++ I L I S +
Sbjct: 251 GII---DTVSASHSISPLIGLLKSNGKLVLLGATEKPFDISAFSLILGRKSIAGSGIGGM 307
Query: 306 AEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGDVRFRFTL 352
E EM++ AE IK +E IS + ++T R+ GDVR+RF +
Sbjct: 308 QETQEMIDFAAEHGIKAEIEI--ISMDYVNTAMDRLAKGDVRYRFVI 352
>At3g19450 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 365
Score = 166 bits (419), Expect = 7e-41
Identities = 114/332 (34%), Positives = 165/332 (49%), Gaps = 16/332 (4%)
Query: 27 YPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGL 86
Y + DV I++ CG+C +D+H K + G P+V GHE++G+V+ +G
Sbjct: 28 YTLRSTGADDVYIKVICCGICHTDIHQIKNDLGMSNYPMVPGHEVVGEVLEVGSDVSK-F 86
Query: 87 KVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEH 146
VGD VGVG V C C C+++ EQYC K + +Y+ Y DG QGG+A + V++
Sbjct: 87 TVGDVVGVGVVVGCCGSCKPCSSELEQYCNKRIWSYNDVY-TDGKPTQGGFADTMIVNQK 145
Query: 147 FVIPIPESLETNNVAPLLCGGATVYSPLKR-NXXXXXXXXXXXXXXXXXXXXXLLAKAMG 205
FV+ IPE + APLLC G TVYSPL +AKAMG
Sbjct: 146 FVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLMASGLKGGILGLGGVGHMGVKIAKAMG 205
Query: 206 AEVYAISRS-HAKEETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSAVDFGKLP 264
V IS S KEE + LGAD Y+ + D + D+LD+++ +D
Sbjct: 206 HHVTVISSSDKKKEEAIEHLGADDYVVSSDPAEMQRLADSLDYIIDTVPVFHPLD--PYL 263
Query: 265 KILKAQG---VIASISVPDQHEAIHLHPAQLLGFQ-ITQSCLASRAEIIEMLNLVAEKKI 320
LK G ++ I+ P Q + P +LG + I+ S + S E E+L EK +
Sbjct: 264 ACLKLDGKLILMGVINTPLQ----FVTPLVILGRKVISGSFIGSIKETEEVLAFCKEKGL 319
Query: 321 KLWVETVPISEENISTVFKRMESGDVRFRFTL 352
+ETV I E NI+ F+R+ DVR+RF +
Sbjct: 320 TSTIETVKIDELNIA--FERLRKNDVRYRFVV 349
>At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 162 bits (409), Expect = 9e-40
Identities = 102/321 (31%), Positives = 159/321 (48%), Gaps = 10/321 (3%)
Query: 35 RDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGV 94
+DV ++ CG+C +D+ AK WG PLV GHEI+G V +G K GD+VGV
Sbjct: 34 KDVRFKVLFCGICHTDLSMAKNEWGLTTYPLVPGHEIVGVVTEVGAKVKK-FNAGDKVGV 92
Query: 95 GAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPES 154
G +C C+ CN+ +E YCPK + T F+D GGY+ H+ E F+I IP++
Sbjct: 93 GYMAGSCRSCDSCNDGDENYCPKMILTSGAKNFDDTMT-HGGYSDHMVCAEDFIIRIPDN 151
Query: 155 LETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXL-LAKAMGAEVYAISR 213
L + APLLC G TVYSP+K + + AKAMG +V IS
Sbjct: 152 LPLDGAAPLLCAGVTVYSPMKYHGLDKPGMHIGVVGLGGLGHVAVKFAKAMGTKVTVIST 211
Query: 214 SHAK-EETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSAV-DFGKLPKILKAQG 271
S K +E +LGAD ++ + D T+D ++ +++SA L +LK +G
Sbjct: 212 SERKRDEAVTRLGADAFLVSRDPKQMKDAMGTMDGII---DTVSATHPLLPLLGLLKNKG 268
Query: 272 VIASISVPDQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIKLWVETVPISE 331
+ + P + + + P + S + E EM++L + I +E IS
Sbjct: 269 KLVMVGAPAEPLELPVFPLIFGRKMVVGSMVGGIKETQEMVDLAGKHNITADIEL--ISA 326
Query: 332 ENISTVFKRMESGDVRFRFTL 352
+ ++T +R+ DV++RF +
Sbjct: 327 DYVNTAMERLAKADVKYRFVI 347
>At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 355
Score = 156 bits (394), Expect = 5e-38
Identities = 111/337 (32%), Positives = 159/337 (46%), Gaps = 15/337 (4%)
Query: 20 LSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLG 79
LSP + + DV + I CGVC +DV ++ G+ K PLV GHEI G V ++G
Sbjct: 23 LSPHTIT--RRSVTTDDVSLTITHCGVCYADVIWSRNQHGDSKYPLVPGHEIAGIVTKVG 80
Query: 80 DKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYAS 139
KVGD VGVG V++C +C CN E C K V T++ DG V +GGY+S
Sbjct: 81 PNVQR-FKVGDHVGVGTYVNSCRECEYCNEGQEVNCAKGVFTFNG-IDHDGSVTKGGYSS 138
Query: 140 HIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKR-NXXXXXXXXXXXXXXXXXXXXX 198
HI VHE + IP + APLLC G TVY+P+ R N
Sbjct: 139 HIVVHERYCYKIPVDYPLESAAPLLCAGITVYAPMMRHNMNQPGKSLGVIGLGGLGHMAV 198
Query: 199 LLAKAMGAEVYAISRS-HAKEETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSA 257
KA G V S S KEE LGA++++ + D +LDF+V + A
Sbjct: 199 KFGKAFGLSVTVFSTSISKKEEALNLLGAENFVISSDHDQMKALEKSLDFLVDTASGDHA 258
Query: 258 VDFGKLPKILKAQGVIASISVPDQHEAIHLHPAQL-LGFQITQSCLASRAEII-EMLNLV 315
F +LK G + P + I + PA L LG ++ + +I +ML+
Sbjct: 259 --FDPYMSLLKIAGTYVLVGFPSE---IKISPANLNLGMRMLAGSVTGGTKITQQMLDFC 313
Query: 316 AEKKIKLWVETVPISEENISTVFKRMESGDVRFRFTL 352
A KI +E +PI + I+ +R+ D+++RF +
Sbjct: 314 AAHKIYPNIEVIPI--QKINEALERVVKKDIKYRFVI 348
>YOL086c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 108 bits (269), Expect = 2e-23
Identities = 95/359 (26%), Positives = 151/359 (41%), Gaps = 22/359 (6%)
Query: 1 MSYPDNFEGFAVVDSHKKWLSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWG- 59
MS P+ +G +SH K L + + P + N ++ I ++ GVC +D+H G+W
Sbjct: 1 MSIPETQKGVIFYESHGK-LEYKDIPVPKPKAN--ELLINVKYSGVCHTDLHAWHGDWPL 57
Query: 60 EMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFV 119
+KLPLV GHE G VV +G+ G K+GD G+ +C+ C C NE CP
Sbjct: 58 PVKLPLVGGHEGAGVVVGMGENVK-GWKIGDYAGIKWLNGSCMACEYCELGNESNCPHAD 116
Query: 120 TTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLK-RNX 178
+ GY G + + IP+ + VAP+LC G TVY LK N
Sbjct: 117 LS--------GYTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSANL 168
Query: 179 XXXXXXXXXXXXXXXXXXXXLLAKAMGAEVYAISRSHAKEETSKQLGADHYIATEDE--- 235
AKAMG V I KEE + +G + +I E
Sbjct: 169 MAGHWVAISGAAGGLGSLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFIDFTKEKDI 228
Query: 236 -GWETKYFDTLDFMVLCGNSLSAVDFGKLPKILKAQGVIASISVPDQHEAI-HLHPAQLL 293
G K D V+ S+S + ++A G + +P + + +
Sbjct: 229 VGAVLKATDGGAHGVI-NVSVSEAAIEASTRYVRANGTTVLVGMPAGAKCCSDVFNQVVK 287
Query: 294 GFQITQSCLASRAEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGDVRFRFTL 352
I S + +RA+ E L+ A +K ++ V +S + ++++ME G + R+ +
Sbjct: 288 SISIVGSYVGNRADTREALDFFARGLVKSPIKVVGLS--TLPEIYEKMEKGQIVGRYVV 344
>YMR303c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 107 bits (268), Expect = 2e-23
Identities = 94/364 (25%), Positives = 149/364 (40%), Gaps = 32/364 (8%)
Query: 1 MSYPDNFEGFAVVDSHKKWLSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWG- 59
MS P+ + +S+ K E P + P ++ I ++ GVC +D+H G+W
Sbjct: 1 MSIPETQKAIIFYESNGKL---EHKDIPVPKPKPNELLINVKYSGVCHTDLHAWHGDWPL 57
Query: 60 EMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFV 119
KLPLV GHE G VV +G+ G K+GD G+ +C+ C C NE CP
Sbjct: 58 PTKLPLVGGHEGAGVVVGMGENVK-GWKIGDYAGIKWLNGSCMACEYCELGNESNCPHAD 116
Query: 120 TTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLK-RNX 178
+ GY G + + IP+ + VAP+LC G TVY LK N
Sbjct: 117 LS--------GYTHDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGITVYKALKSANL 168
Query: 179 XXXXXXXXXXXXXXXXXXXXLLAKAMGAEVYAISRSHAKEETSKQLGADHYIATEDEGWE 238
AKAMG V I KEE LG + +I
Sbjct: 169 RAGHWAAISGAAGGLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEVFIDF------ 222
Query: 239 TKYFDTLDFMVLCGN---------SLSAVDFGKLPKILKAQGVIASISVPDQHE-AIHLH 288
TK D + +V N S+S + +A G + + +P + + +
Sbjct: 223 TKEKDIVSAVVKATNGGAHGIINVSVSEAAIEASTRYCRANGTVVLVGLPAGAKCSSDVF 282
Query: 289 PAQLLGFQITQSCLASRAEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGDVRF 348
+ I S + +RA+ E L+ A +K ++ V +S ++ ++++ME G +
Sbjct: 283 NHVVKSISIVGSYVGNRADTREALDFFARGLVKSPIKVVGLS--SLPEIYEKMEKGQIAG 340
Query: 349 RFTL 352
R+ +
Sbjct: 341 RYVV 344
>YBR145w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 107 bits (267), Expect = 3e-23
Identities = 86/331 (25%), Positives = 137/331 (40%), Gaps = 29/331 (8%)
Query: 34 PRDVDIEIEACGVCGSDVHCAKGNWG-EMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRV 92
P ++ + ++ GVC SD+H G+W ++K PL+ GHE G VV+LG G KVGD
Sbjct: 34 PNEILVHVKYSGVCHSDLHAWHGDWPFQLKFPLIGGHEGAGVVVKLGSNVK-GWKVGDFA 92
Query: 93 GVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIP 152
G+ C+ C C NE CP T G+ G + + IP
Sbjct: 93 GIKWLNGTCMSCEYCEVGNESQCPYLDGT--------GFTHDGTFQEYATADAVQAAHIP 144
Query: 153 ESLETNNVAPLLCGGATVYSPLKR-NXXXXXXXXXXXXXXXXXXXXXLLAKAMGAEVYAI 211
++ VAP+LC G TVY LKR N A AMG V I
Sbjct: 145 PNVNLAEVAPILCAGITVYKALKRANVIPGQWVTISGACGGLGSLAIQYALAMGYRVIGI 204
Query: 212 SRSHAKEETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGN---------SLSAVDFGK 262
+AK + +QLG + +I +E D + ++ N S+S
Sbjct: 205 DGGNAKRKLFEQLGGEIFIDFTEEK------DIVGAIIKATNGGSHGVINVSVSEAAIEA 258
Query: 263 LPKILKAQGVIASISVP-DQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIK 321
+ + G + + +P + + + I SC+ +RA+ E L+ A IK
Sbjct: 259 STRYCRPNGTVVLVGMPAHAYCNSDVFNQVVKSISIVGSCVGNRADTREALDFFARGLIK 318
Query: 322 LWVETVPISEENISTVFKRMESGDVRFRFTL 352
+ +S+ + +F +ME G++ R+ +
Sbjct: 319 SPIHLAGLSD--VPEIFAKMEKGEIVGRYVV 347
>CE12214 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 99.4 bits (246), Expect = 8e-21
Identities = 91/346 (26%), Positives = 150/346 (43%), Gaps = 40/346 (11%)
Query: 20 LSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKL-PLVVGHEIIGKVVRL 78
L +V P Q N ++ ++IE G+C SD+H +G++ + PL+ GHE G VV +
Sbjct: 22 LEVRQVSVPQPQEN--ELLVKIEYSGICHSDLHTWEGDFEYASICPLIGGHEGAGTVVTI 79
Query: 79 GDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYA 138
G K G +GDR G+ + CL+C C +E C + Q Y G G +
Sbjct: 80 GSKVK-GWNIGDRAGIKLINANCLNCEYCKTGHEPLC-----DHIQNY---GIDRHGTFQ 130
Query: 139 SHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLK-RNXXXXXXXXXXXXXXXXXXXX 197
++ + + I + AP+LCGG T Y LK N
Sbjct: 131 EYLTIRDIDAIKVSNDTNLAAAAPVLCGGVTAYKSLKATNVKPGQIVVLTGAGGGLGSFG 190
Query: 198 XLLAKAMGAEVYAISRSHAKEETSKQLGADHYIATEDEGWETKYFDTLDFM-----VLCG 252
AKAMG V A+ +KE+ + LGA+ W FDT D + + G
Sbjct: 191 IQYAKAMGMRVVAVDHI-SKEDHCRNLGAE---------WFVDAFDTPDIVAHIRKLTNG 240
Query: 253 NSLSAVDFGKLPK-------ILKAQGVIASISVPDQHEAIHLHPAQLLGFQIT--QSCLA 303
+ V F K ++ +G + + +P + I L L+ +IT S +
Sbjct: 241 GAHGVVSFAAAKKPMEYALEYVRKRGTVVFVGLP-KDGTIPLDTLSLICNEITVKGSIVG 299
Query: 304 SRAEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGDVRFR 349
SR ++ E ++ + + + +E V + E++ +V++RM+ G V R
Sbjct: 300 SRMDVDEAIDFITRGIVHVPIELVKL--EDVPSVYQRMKDGKVTSR 343
>CE20628 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 408
Score = 98.2 bits (243), Expect = 2e-20
Identities = 84/348 (24%), Positives = 147/348 (42%), Gaps = 34/348 (9%)
Query: 28 PAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEM-KLPLVVGHEIIGKVVRLGDKCDTGL 86
P Q N ++ +++E G+C SDVH G++ + K P++ GHE G V+ +G K
Sbjct: 28 PIPQPNEDELLVKMEYSGICHSDVHTWLGDFHYVSKCPMIGGHEGAGSVISVGSKVKNW- 86
Query: 87 KVGDRVGVGAQVSA----------------CLDCNRCNNDNEQYCPKFVTTYSQPYFEDG 130
++GD+VG+ + CL+C C +E CP Q Y
Sbjct: 87 QIGDKVGIKVSQTLNSSSLNFNIFQLVQGNCLNCEYCQTGHEPLCPHVWNIGVQKY---- 142
Query: 131 YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXX 190
G + + + + I IP+S+ AP+LCGG T Y LK +
Sbjct: 143 ----GTFQEYATIRDVDAIKIPKSMNMAAAAPVLCGGVTAYKALKESEVKSGQIVAVTGA 198
Query: 191 XXXXXXXXL-LAKAMGAEVYAISRSHAKEETSKQLGADHYI---ATEDEGWETKYFDTLD 246
+ A+AMG V AI +KE K LGA+ ++ TED +
Sbjct: 199 GGGLGSFAIQYARAMGMRVVAIDHP-SKEAHCKSLGAEWFVDAFGTEDIVAHIREITDGG 257
Query: 247 FMVLCGNSLSAVDFGKLPKILKAQGVIASISV-PDQHEAIHLHPAQLLGFQITQSCLASR 305
+ + + V K + ++ +G + + + D + P +I S + SR
Sbjct: 258 AHGVVNFAAAKVPMEKALEYVRKRGTVVFVGLAKDSKILVDTIPLIFNAVKIKGSIVGSR 317
Query: 306 AEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGDVRFRFTLT 353
++ E ++ VA + + +E V + E+++ V+ +M G + R L+
Sbjct: 318 LDVNEAMDFVARGAVNVPLELVKL--EDVAEVYTKMHDGKINSRQLLS 363
>YMR083w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 96.3 bits (238), Expect = 6e-20
Identities = 83/331 (25%), Positives = 137/331 (41%), Gaps = 17/331 (5%)
Query: 28 PAKQFNPRDVDIEIEACGVCGSDVHCAKGNWG-EMKLPLVVGHEIIGKVVRLGDKCDTGL 86
P + P ++ I ++ GVC +D+H G+W +KLPLV GHE G VV+LG G
Sbjct: 52 PVPEPKPNEILINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGHEGAGVVVKLGSNVK-GW 110
Query: 87 KVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEH 146
KVGD G+ +C+ C C + +E CP + GY G +
Sbjct: 111 KVGDLAGIKWLNGSCMTCEFCESGHESNCPDADLS--------GYTHDGSFQQFATADAI 162
Query: 147 FVIPIPESLETNNVAPLLCGGATVYSPLKR-NXXXXXXXXXXXXXXXXXXXXXLLAKAMG 205
I + + VAP+LC G TVY LK + A AMG
Sbjct: 163 QAAKIQQGTDLAEVAPILCAGVTVYKALKEADLKAGDWVAISGAAGGLGSLAVQYATAMG 222
Query: 206 AEVYAISRSHAKEETSKQLGADHYI---ATEDEGWETKYFDTLDFMVLCGNSLSAVDFGK 262
V I KE+ K+LG + +I T++ + + + S+S
Sbjct: 223 YRVLGIDAGEEKEKLFKKLGGEVFIDFTKTKNMVSDIQEATKGGPHGVINVSVSEAAISL 282
Query: 263 LPKILKAQGVIASISVP-DQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIK 321
+ ++ G + + +P + + + + I S + +RA+ E L+ + IK
Sbjct: 283 STEYVRPCGTVVLVGLPANAYVKSEVFSHVVKSINIKGSYVGNRADTREALDFFSRGLIK 342
Query: 322 LWVETVPISEENISTVFKRMESGDVRFRFTL 352
++ V +SE + V+ ME G + R+ +
Sbjct: 343 SPIKIVGLSE--LPKVYDLMEKGKILGRYVV 371
>SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 350
Score = 93.2 bits (230), Expect = 5e-19
Identities = 93/367 (25%), Positives = 150/367 (40%), Gaps = 36/367 (9%)
Query: 1 MSYPDNFEGFAVVDSHKKWLSPEKVVY---PAKQFNPRDVDIEIEACGVCGSDVHCAKGN 57
M+ PD + AV +H PE V + P + +V + I+ GVC +D+H +G+
Sbjct: 1 MTIPDK-QLAAVFHTHG---GPENVKFEEVPVAEPGQDEVLVNIKYTGVCHTDLHALQGD 56
Query: 58 WG-EMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCP 116
W K+PL+ GHE G VV++G T LK+GDRVGV S+C +C C E CP
Sbjct: 57 WPLPAKMPLIGGHEGAGVVVKVGAGV-TRLKIGDRVGVKWMNSSCGNCEYCMKAEETICP 115
Query: 117 KFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKR 176
+ GY G + + + IPES+ AP++C G T Y LK
Sbjct: 116 HIQLS--------GYTVDGTFQHYCIANATHATIIPESVPLEVAAPIMCAGITCYRALKE 167
Query: 177 NXXXXXXXXXXXXXXXXXXXXXL-LAKAMGAEVYAISRSHAKEETSKQLGADHYIATEDE 235
+ + AKAM V AI K E K GA+ ++ + E
Sbjct: 168 SKVGPGEWICIPGAGGGLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFLDFKKE 227
Query: 236 GWETKYFDTLDFMVLCGN---------SLSAVDFGKLPKILKAQGVIASISVPDQHE-AI 285
D ++ + N S S + + + + ++S+P +
Sbjct: 228 A------DMIEAVKAATNGGAHGTLVLSTSPKSYEQAAGFARPGSTMVTVSMPAGAKLGA 281
Query: 286 HLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIKLWVETVPISEENISTVFKRMESGD 345
+ + +I S + +R + IE L V+ +K + + P S + V++ M
Sbjct: 282 DIFWLTVKMLKICGSHVGNRIDSIEALEYVSRGLVKPYYKVQPFS--TLPDVYRLMHENK 339
Query: 346 VRFRFTL 352
+ R L
Sbjct: 340 IAGRIVL 346
>CE12212 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 349
Score = 92.0 bits (227), Expect = 1e-18
Identities = 84/324 (25%), Positives = 138/324 (41%), Gaps = 26/324 (8%)
Query: 36 DVDIEIEACGVCGSDVHCAKGNWGEMKL-PLVVGHEIIGKVVRLGDKCDTGLKVGDRVGV 94
++ ++IE G+C SD+H G+ +M + PLV GHE G VV++G K TG ++GD+ GV
Sbjct: 35 EILVKIEYSGICHSDLHVWLGDLKDMSVCPLVGGHEGAGSVVQIG-KNVTGWQLGDKAGV 93
Query: 95 GAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPES 154
CL+C C +E C + Q Y G+ G + ++ + I +
Sbjct: 94 KLMNFNCLNCEFCKKGHEPLC-----HHIQNY---GFDRSGTFQEYLTIRGVDAAKINKD 145
Query: 155 LETNNVAPLLCGGATVYSPLKR-NXXXXXXXXXXXXXXXXXXXXXLLAKAMGAEVYAISR 213
AP+LC G TVY LK N A AMG V A+
Sbjct: 146 TNLAAAAPILCAGVTVYKALKESNVAPGQIIVLTGAGGGLGSLAIQYACAMGMRVVAMDH 205
Query: 214 SHAKEETSKQLGADHYIATEDEGWETKYFDTLDFMVLCGNSLSAVDFGKLPK-------I 266
+KE K LGA+ ++ + +ET + + G ++F K
Sbjct: 206 G-SKEAHCKGLGAEWFV----DAFETPDIVSHITKLTEGGPHGVINFAVARKPMEQAVEY 260
Query: 267 LKAQGVIASISVP-DQHEAIHLHPAQLLGFQITQSCLASRAEIIEMLNLVAEKKIKLWVE 325
++ +G + + +P D P I S + SR ++ E + V +K+ +E
Sbjct: 261 VRKRGTVVFVGLPKDSKVTFDTTPFIFNAITIKGSIVGSRLDVDEAMEFVTRGIVKVPLE 320
Query: 326 TVPISEENISTVFKRMESGDVRFR 349
V + E++ V++RM G + R
Sbjct: 321 LVKL--EDVPAVYQRMLDGKINSR 342
>At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 383
Score = 75.5 bits (184), Expect = 1e-13
Identities = 73/254 (28%), Positives = 103/254 (39%), Gaps = 27/254 (10%)
Query: 4 PDNFEGFAVVDSHKKWLSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKL 63
P F AV K L+ E+ P + N ++ I+ +ACGVC SD+H KG
Sbjct: 8 PGGFMRGAVYREPNKPLTIEEFHIPRPKSN--EILIKTKACGVCHSDLHVMKGEI-PFAS 64
Query: 64 PLVVGHEIIGKVVRLGDKCD----TGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFV 119
P V+GHEI G+VV G D +G RV VGA + C C+ C ++ C F
Sbjct: 65 PCVIGHEITGEVVEHGPLTDHKIINRFPIGSRV-VGAFIMPCGTCSYCAKGHDDLCEDFF 123
Query: 120 T-TYSQPYFEDG--------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLL 164
++ DG GG A + H + P+PESL + A L
Sbjct: 124 AYNRAKGTLYDGETRLFLRHDDSPVYMYSMGGMAEYCVTPAHGLAPLPESLPYSESAILG 183
Query: 165 CGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXL-LAKAMGA-EVYAISRSHAKEETSK 222
C T Y + L +A+A GA ++ A+ K + +K
Sbjct: 184 CAVFTAYGAMAHAAEIRPGDSIAVIGIGGVGSSCLQIARAFGASDIIAVDVQDDKLQKAK 243
Query: 223 QLGADHYI--ATED 234
LGA H + A ED
Sbjct: 244 TLGATHIVNAAKED 257
>7298873 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 71.2 bits (173), Expect = 2e-12
Identities = 58/205 (28%), Positives = 87/205 (42%), Gaps = 14/205 (6%)
Query: 28 PAKQFNPRDVDIEIEACGVCGSDVH-CAKGNWGEMKL--PLVVGHEIIGKVVRLGDKCDT 84
P + +V + +++ G+CGSDVH A G G+ L P+++GHE G V +LG K T
Sbjct: 22 PIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIGHESAGVVAKLGKKVTT 81
Query: 85 GLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVH 144
LKVGDRV + V C C+ C CP V + PY G + +
Sbjct: 82 -LKVGDRVAIEPGV-PCRKCDHCKQGKYNLCPGMVFCATPPY-------DGNLTRYYKHA 132
Query: 145 EHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXLLAKAM 204
F +P+ + A L V++ KR + A+AM
Sbjct: 133 ADFCFKLPDHVTMEEGALLEPLSVGVHA-CKRAEVTLGSKVLILGAGPIGLVTLMAAQAM 191
Query: 205 GA-EVYAISRSHAKEETSKQLGADH 228
GA E+ + + +K+LGA H
Sbjct: 192 GASEILITDLVQQRLDVAKELGATH 216
>YAL060w [Q] KOG0024 Sorbitol dehydrogenase
Length = 382
Score = 69.3 bits (168), Expect = 8e-12
Identities = 75/284 (26%), Positives = 117/284 (40%), Gaps = 60/284 (21%)
Query: 36 DVDIEIEACGVCGSDVH--------------CAKGNWGEMKLPLVVGHEIIGKVVRLGDK 81
+V I++ CG+CGSD+H C K LPL +GHE+ G V ++G K
Sbjct: 28 EVIIDVSWCGICGSDLHEYLDGPIFMPKDGECHK--LSNAALPLAMGHEMSGIVSKVGPK 85
Query: 82 CDTGLKVGDRVGVGAQVSACLD--------------CNRCNNDNEQYCPKFVTTYSQPYF 127
T +KVGD V V A S+C D C+ C +E C
Sbjct: 86 V-TKVKVGDHVVVDA-ASSCADLHCWPHSKFYNSKPCDACQRGSENLCT----------- 132
Query: 128 EDGYVG----QGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXX 183
G+VG GG+A + V +H +IP+P+ + +VA L+ + + +K +
Sbjct: 133 HAGFVGLGVISGGFAEQVVVSQHHIIPVPKEIPL-DVAALVEPLSVTWHAVKISGFKKGS 191
Query: 184 XXXXXXXXXXXXXXXLLAKAMGAEVYAISR-SHAKEETSKQLGADHYIATEDEGWE---- 238
L+ K MGA +S + + E +K+LG + + ++ G +
Sbjct: 192 SALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAKKLGVEVFNPSK-HGHKSIEI 250
Query: 239 ----TKYFDTLDFMVLCGNSLSAVDFGKLPKILKAQGVIASISV 278
TK D D+ C S V F K L +G +I+V
Sbjct: 251 LRGLTKSHDGFDYSYDC--SGIQVTFETSLKALTFKGTATNIAV 292
>Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 67.8 bits (164), Expect = 2e-11
Identities = 77/306 (25%), Positives = 124/306 (40%), Gaps = 31/306 (10%)
Query: 11 AVVDSHKKWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGH 69
AV+ KK S E+V V P K +V I++ A G+CG+D H G LP+++GH
Sbjct: 13 AVLWELKKPFSIEEVEVAPPKA---HEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILGH 68
Query: 70 EIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFED 129
E G V +G+ T +K GD+V + + C C C N YC K + Q +D
Sbjct: 69 EAAGIVESVGEGVTT-VKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126
Query: 130 G-------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKR 176
G ++G ++ + V E+ V I + V + CG +T Y
Sbjct: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186
Query: 177 NXXXXXXXXXXXXXXXXXXXXXLL-AKAMG-AEVYAISRSHAKEETSKQLGADHYIATED 234
++ KA G A + A+ + K +K+LGA I +D
Sbjct: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246
Query: 235 EGWETKYFDTLDFMVLCGNSLSAVDFGKLPKIL-------KAQGVIASISVPDQHEAIHL 287
++ + L M G S G+L ++ +A G + VP + + +
Sbjct: 247 --YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSM 304
Query: 288 HPAQLL 293
+P LL
Sbjct: 305 NPMLLL 310
>7299382 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 67.8 bits (164), Expect = 2e-11
Identities = 57/205 (27%), Positives = 86/205 (41%), Gaps = 14/205 (6%)
Query: 28 PAKQFNPRDVDIEIEACGVCGSDVH-CAKGNWGEMKL--PLVVGHEIIGKVVRLGDKCDT 84
P + +V + +++ G+CGSDVH A G G+ L P+++GHE G V +LG K T
Sbjct: 22 PIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIGHEAAGVVAKLGKKVTT 81
Query: 85 GLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVH 144
LKVGDRV + V C C+ C C V + PY G + +
Sbjct: 82 -LKVGDRVAIEPGV-PCRYCDHCKQGRYNLCADMVFCATPPY-------DGNLTRYYKHA 132
Query: 145 EHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXLLAKAM 204
F +P+ + A L V++ +R L A+AM
Sbjct: 133 ADFCFKLPDHVSMEEGALLEPLSVGVHA-CRRAGVGLGSKVLILGAGPIGLVTLLAAQAM 191
Query: 205 GA-EVYAISRSHAKEETSKQLGADH 228
GA E+ + + +K+LGA H
Sbjct: 192 GASEILITDLVQQRLDVAKELGATH 216
>Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 66.2 bits (160), Expect = 7e-11
Identities = 80/306 (26%), Positives = 124/306 (40%), Gaps = 31/306 (10%)
Query: 11 AVVDSHKKWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGH 69
AV+ KK S E+V V P K +V I++ A G+C SD H GN LP+++GH
Sbjct: 13 AVLWELKKPFSIEEVEVAPPKA---HEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILGH 68
Query: 70 EIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFED 129
E G V +G+ T +K GD+V + C C C N YC K + +D
Sbjct: 69 EAAGIVESVGEGVTT-VKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126
Query: 130 G-------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVY-SPLK 175
G +VG ++ + V E+ V I + V + CG +T Y S +K
Sbjct: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186
Query: 176 RNXXXXXXXXXXXXXXXXXXXXXLLAKAMG-AEVYAISRSHAKEETSKQLGADHYIATED 234
+ KA G A + A+ + K +K+LGA I +D
Sbjct: 187 VAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246
Query: 235 EGWETKYFDTLDFMVLCGNSLSAVDFGKLPKIL-------KAQGVIASISVPDQHEAIHL 287
++ + L M G S G+L ++ +A G + VP + + +
Sbjct: 247 --YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304
Query: 288 HPAQLL 293
+P LL
Sbjct: 305 NPMLLL 310
>Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 62.0 bits (149), Expect = 1e-09
Identities = 77/306 (25%), Positives = 123/306 (40%), Gaps = 31/306 (10%)
Query: 11 AVVDSHKKWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGH 69
AV+ KK S E V V P K + +V I++ A G+C +D H GN LP+++GH
Sbjct: 13 AVLWEVKKPFSIEDVEVAPPKAY---EVRIKMVAVGICHTDDHVVSGNL-VTPLPVILGH 68
Query: 70 EIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFED 129
E G V +G+ T +K GD+V + C C C N YC K + +D
Sbjct: 69 EAAGIVESVGEGVTT-VKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126
Query: 130 G-------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVY-SPLK 175
G ++G ++ + V E+ V I + V + CG +T Y S +
Sbjct: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186
Query: 176 RNXXXXXXXXXXXXXXXXXXXXXLLAKAMG-AEVYAISRSHAKEETSKQLGADHYIATED 234
+ KA G A + A+ + K +K+LGA I +D
Sbjct: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246
Query: 235 EGWETKYFDTLDFMVLCGNSLSAVDFGKLPKIL-------KAQGVIASISVPDQHEAIHL 287
++ + L M G S G+L ++ +A G + VP + + +
Sbjct: 247 --YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304
Query: 288 HPAQLL 293
+P LL
Sbjct: 305 NPMLLL 310
>Hs4501931 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 58.9 bits (141), Expect = 1e-08
Identities = 76/306 (24%), Positives = 122/306 (39%), Gaps = 31/306 (10%)
Query: 11 AVVDSHKKWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGH 69
AV+ KK S E V V P K + +V I++ A G+C +D H G LP+++GH
Sbjct: 13 AVLWEVKKPFSIEDVEVAPPKAY---EVRIKMVAVGICRTDDHVVSGKL-VTPLPVILGH 68
Query: 70 EIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFED 129
E G V +G+ T +K GD+V + C C C N YC K + +D
Sbjct: 69 EAAGIVESVGEGVTT-VKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126
Query: 130 G-------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVY-SPLK 175
G ++G ++ + V E+ V I + + V + CG +T Y S +
Sbjct: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASKLEKVCLIGCGFSTGYGSAVN 186
Query: 176 RNXXXXXXXXXXXXXXXXXXXXXLLAKAMG-AEVYAISRSHAKEETSKQLGADHYIATED 234
+ KA G A + A+ + K +K LGA I +D
Sbjct: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKVLGATECINPQD 246
Query: 235 EGWETKYFDTLDFMVLCGNSLSAVDFGKLPKIL-------KAQGVIASISVPDQHEAIHL 287
++ + L M G S G+L ++ +A G + VP + + +
Sbjct: 247 --YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304
Query: 288 HPAQLL 293
+P LL
Sbjct: 305 NPMLLL 310
>At5g51970 [Q] KOG0024 Sorbitol dehydrogenase
Length = 364
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/93 (38%), Positives = 49/93 (51%), Gaps = 7/93 (7%)
Query: 34 PRDVDIEIEACGVCGSDVHCAKGNWGE---MKLPLVVGHEIIGKVVRLGDKCDTGLKVGD 90
P DV + ++A G+CGSDVH K +K P+V+GHE G + +G++ L VGD
Sbjct: 41 PHDVRVRMKAVGICGSDVHYLKTMRCADFVVKEPMVIGHECAGIIEEVGEEV-KHLVVGD 99
Query: 91 RVGVGAQVSACLDCNRCNNDNEQYCP--KFVTT 121
RV + +S C CN C CP KF T
Sbjct: 100 RVALEPGIS-CWRCNLCREGRYNLCPEMKFFAT 131
>YDL246c [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 57.4 bits (137), Expect = 3e-08
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 15/140 (10%)
Query: 33 NPRDVDIEIEACGVCGSDVHCAK-GNWGE--MKLPLVVGHEIIGKVVRLGDKCDTGLKVG 89
+P V + I+A G+CGSD+H + G G+ +K P+V+GHE G+VV +GD T +KVG
Sbjct: 29 DPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAV-TRVKVG 87
Query: 90 DRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVI 149
DRV + V + + + CP + P G + E F++
Sbjct: 88 DRVAIEPGVPSRYS-DETKEGSYNLCPHMAFAATPPI-------DGTLVKYYLSPEDFLV 139
Query: 150 PIPESL---ETNNVAPLLCG 166
+PE + E V PL G
Sbjct: 140 KLPEGVSYEEGACVEPLSVG 159
>YJR159w [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 57.0 bits (136), Expect = 4e-08
Identities = 44/140 (31%), Positives = 66/140 (46%), Gaps = 15/140 (10%)
Query: 33 NPRDVDIEIEACGVCGSDVHCAK-GNWGE--MKLPLVVGHEIIGKVVRLGDKCDTGLKVG 89
+P V + I+A G+CGSD+H + G G+ +K P+V+GHE G+VV +GD T +KVG
Sbjct: 29 DPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAV-TRVKVG 87
Query: 90 DRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVI 149
DRV + V + + CP + P G + E F++
Sbjct: 88 DRVAIEPGVPSRYS-DETKEGRYNLCPHMAFAATPPI-------DGTLVKYYLSPEDFLV 139
Query: 150 PIPESL---ETNNVAPLLCG 166
+PE + E V PL G
Sbjct: 140 KLPEGVSYEEGACVEPLSVG 159
>Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 374
Score = 57.0 bits (136), Expect = 4e-08
Identities = 86/364 (23%), Positives = 146/364 (39%), Gaps = 41/364 (11%)
Query: 11 AVVDSHKKWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGH 69
AV+ K+ S E++ V P K ++V I+I A G+C +D H KG K P++VGH
Sbjct: 13 AVLWEQKQPFSIEEIEVAPPKT---KEVRIKILATGICRTDDHVIKGTM-VSKFPVIVGH 68
Query: 70 EIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFED 129
E G V +G+ T +K GD+V + + C +CN C N + C + T + D
Sbjct: 69 EATGIVESIGEGVTT-VKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDIT-GRGVLAD 125
Query: 130 G-------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVY-SPLK 175
G ++ + + V E V I ++ V + CG +T Y + +K
Sbjct: 126 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVK 185
Query: 176 RNXXXXXXXXXXXXXXXXXXXXXLLAKAMGA-EVYAISRSHAKEETSKQLGADHYIATED 234
+ K+ GA + I + K E + +GA I+ +D
Sbjct: 186 TGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 245
Query: 235 EGWETKYFDTLDFMVLCGNSLSAV--DFGKLPKILKA-------QGVIASISVPDQHEAI 285
TK + + GN++ G L ++ A G + VP + +
Sbjct: 246 ---STKPISEV-LSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 301
Query: 286 HLHPAQLLGFQITQSC----LASRAEIIEMLNLVAEKKIKL-WVETVPISEENISTVFKR 340
P L + + C L SR ++ +++ KK L + T + + IS F+
Sbjct: 302 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 361
Query: 341 MESG 344
+ SG
Sbjct: 362 LNSG 365
>CE06216 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/205 (27%), Positives = 83/205 (39%), Gaps = 16/205 (7%)
Query: 28 PAKQFNPRDVDIEIEACGVCGSDVH-CAKGNWGE--MKLPLVVGHEIIGKVVRLGDKCDT 84
P + PR V ++I G+CGSDVH G G +K P+V+GHE G V +G +
Sbjct: 22 PISKPGPRQVLVKINTVGICGSDVHFLTHGAIGSFVVKEPMVLGHESSGVVSEIGSEV-K 80
Query: 85 GLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVH 144
G KVGDR+ + + C C C CP + P G S VH
Sbjct: 81 GFKVGDRIAMEPGL-PCKLCEHCKIGRYNLCPDMRFFATPPV--------NGALSRFVVH 131
Query: 145 E-HFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXLLAKA 203
+ F +P++L + A LL + +R L AKA
Sbjct: 132 DADFCFKLPDNLSFEDGA-LLEPLSVAIQACRRGTVQMGQKILVLGAGPIGVLNLLTAKA 190
Query: 204 MGA-EVYAISRSHAKEETSKQLGAD 227
+GA +V + + ++ LGAD
Sbjct: 191 IGASKVVITDLNDERLALARLLGAD 215
>SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 56.2 bits (134), Expect = 7e-08
Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query: 37 VDIEIEACGVCGSDVHCAK-GNWGE--MKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVG 93
V + I+A G+CGSDVH K G G+ +K P+++GHE G VV +G K + LK GD V
Sbjct: 32 VKVAIKATGICGSDVHYWKEGGIGDFILKKPMILGHESAGVVVEVG-KGVSSLKPGDPVA 90
Query: 94 VGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVHEHFVIPIPE 153
V C C+ C + CP + PY G ++ E F +P+
Sbjct: 91 V-EPGCVCRLCDYCRSGRYNLCPHMEFAATPPY-------DGTLRTYYITTEDFCTKLPK 142
Query: 154 SLETNNVA 161
+ A
Sbjct: 143 QISVEEGA 150
>CE23822 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 384
Score = 55.1 bits (131), Expect = 2e-07
Identities = 75/309 (24%), Positives = 116/309 (37%), Gaps = 32/309 (10%)
Query: 11 AVVDSHKKWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGH 69
AV S K LS E + V P K +V ++I VC +D + G+ E P+V+GH
Sbjct: 14 AVAWSAKAPLSIETIQVAPPKA---HEVRVKILYTAVCHTDAYTLDGHDPEGLFPVVLGH 70
Query: 70 EIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFED 129
E G V +G+ TG GD V V V C +C C N C K + + D
Sbjct: 71 EGSGIVESVGEGV-TGFAPGDHV-VPLYVPQCKECEYCKNPKTNLCQKIRISQGNGFMPD 128
Query: 130 G-------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKR 176
G ++G ++ + V + + + V+ L CG +T Y +
Sbjct: 129 GSSRFTCNGKQLFHFMGCSTFSEYTVVADISLCKVNPEAPLEKVSLLGCGISTGYGAVLN 188
Query: 177 NXXXXXXXXXXXXXXXXXXXXXLL-AKAMGA-EVYAISRSHAKEETSKQLGADHYIATED 234
++ AKA GA ++ I +K E++K GA I +
Sbjct: 189 TCKVEEGSTVAVWGLGAVGLAVIMGAKAAGAKKIVGIDLIESKFESAKFFGATECINPKS 248
Query: 235 ---------EGWETKYFD-TLDFMVLCGNSLSAVDFGKLPKILKAQGVIASISVPDQHEA 284
+ W + FD D+ C ++ + L K GV I V +
Sbjct: 249 VELPEGKSFQAWLVEQFDGGFDYTFECIGNVHTMR-QALEAAHKGWGVSCIIGVAGAGQE 307
Query: 285 IHLHPAQLL 293
I P QL+
Sbjct: 308 IATRPFQLV 316
>7299380 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 55.1 bits (131), Expect = 2e-07
Identities = 51/214 (23%), Positives = 78/214 (35%), Gaps = 17/214 (7%)
Query: 36 DVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVG 95
+V I+I A GVC +D G E P+V+GHE G V +G+ T K GD V +
Sbjct: 37 EVRIKITATGVCHTDAFTLSGADPEGLFPVVLGHEGAGIVESVGEGV-TNFKAGDHV-IA 94
Query: 96 AQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDG-------------YVGQGGYASHIR 142
+ C +C C + C K T +G ++G +A +
Sbjct: 95 LYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSRLSCKGQQLFHFMGTSTFAEYTV 154
Query: 143 VHEHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXLLA- 201
V + + I E V L CG +T Y L
Sbjct: 155 VADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTCAVWGLGAVGLAVGLGC 214
Query: 202 -KAMGAEVYAISRSHAKEETSKQLGADHYIATED 234
KA ++Y I + K E +K+ G ++ +D
Sbjct: 215 KKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKD 248
>CE06215 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 54.3 bits (129), Expect = 3e-07
Identities = 53/205 (25%), Positives = 85/205 (40%), Gaps = 16/205 (7%)
Query: 28 PAKQFNPRDVDIEIEACGVCGSDVH-CAKGNWGE--MKLPLVVGHEIIGKVVRLGDKCDT 84
P + P V +++ G+CGSDVH G G +K P++VGHE G V +G++
Sbjct: 22 PIPKPGPNQVLVKVHTVGICGSDVHYWTHGAIGPFVVKEPMIVGHETSGIVSEVGNEV-K 80
Query: 85 GLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDGYVGQGGYASHIRVH 144
LKVGDR+ + + C C C CP+ + P G S VH
Sbjct: 81 HLKVGDRIAMEPGL-PCKLCEHCKTGRYNLCPEMRFFATPPVH--------GTLSRFVVH 131
Query: 145 E-HFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXLLAKA 203
+ F +P++L + A + +++ +R + AKA
Sbjct: 132 DADFCFKLPDNLSFEDGALIEPLSVAIHA-CRRGNVQMGHRVLVLGAGPIGVLNLITAKA 190
Query: 204 MGA-EVYAISRSHAKEETSKQLGAD 227
+GA +V + +K+LGAD
Sbjct: 191 VGAGKVVITDLDDGRLALAKKLGAD 215
>YDL168w [Q] KOG0022 Alcohol dehydrogenase class III
Length = 386
Score = 53.1 bits (126), Expect = 6e-07
Identities = 58/241 (24%), Positives = 95/241 (39%), Gaps = 20/241 (8%)
Query: 11 AVVDSHKKWLSPEKVVYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHE 70
AV KK LS E++ A + + +V I+IE VC +D + G+ E P V+GHE
Sbjct: 15 AVAYDAKKPLSVEEITVDAPKAH--EVRIKIEYTAVCHTDAYTLSGSDPEGLFPCVLGHE 72
Query: 71 IIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDG 130
G V +GD T +K GD V + + C C C + C T + DG
Sbjct: 73 GAGIVESVGDDVIT-VKPGDHV-IALYTAECGKCKFCTSGKTNLCGAVRATQGKGVMPDG 130
Query: 131 --------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVY-SPLK 175
++G ++ + V + V+ I + L CG T + + LK
Sbjct: 131 TTRFHNAKGEDIYHFMGCSTFSEYTVVADVSVVAIDPKAPLDAACLLGCGVTTGFGAALK 190
Query: 176 RNXXXXXXXXXXXXXXXXXXXXXLLAKAMGA-EVYAISRSHAKEETSKQLGADHYIATED 234
AK GA ++ AI ++ K++ Q GA ++ ++
Sbjct: 191 TANVQKGDTVAVFGCGTVGLSVIQGAKLRGASKIIAIDINNKKKQYCSQFGATDFVNPKE 250
Query: 235 E 235
+
Sbjct: 251 D 251
>Hs11496891 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 374
Score = 52.4 bits (124), Expect = 1e-06
Identities = 90/358 (25%), Positives = 134/358 (37%), Gaps = 41/358 (11%)
Query: 18 KWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVV 76
K LS E++ V P K +V I+I A VC +D + G E P+++GHE G V
Sbjct: 18 KPLSIEEIEVAPPKA---HEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVE 74
Query: 77 RLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDG------ 130
+G+ T LK GD V + + C +C C N C K T + DG
Sbjct: 75 SVGEGV-TKLKAGDTV-IPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTC 132
Query: 131 -------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKRNXXXXXX 183
Y+G ++ + V + V I V L CG +T Y
Sbjct: 133 KGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLYKVCLLGCGISTGYGAAVNTAKLEPG 192
Query: 184 XXXXXXXXXXXXXXXLLAKAMGAEVYAISR------SHAKEETSKQLGADHYIATED--- 234
LA MG +V SR + K +K+ GA I +D
Sbjct: 193 SVCAVFGLGGVG----LAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDLSK 248
Query: 235 ---EGWETKYFDTLDFMVLCGNSLSAVDFGKLPKILKAQGVIASISVPDQHEAIHLHPAQ 291
E +D+ C ++ + L K GV + V E I P Q
Sbjct: 249 PIQEVLIEMTDGGVDYSFECIGNVKVMR-AALEACHKGWGVSVVVGVAASGEEIATRPFQ 307
Query: 292 LLGFQITQSCLASRAEIIEML-NLVAE---KKIKL-WVETVPISEENISTVFKRMESG 344
L+ + + + +E + LV+E KKIK+ T +S + I+ F+ M SG
Sbjct: 308 LVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSG 365
>CE22292_2 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 340
Score = 52.0 bits (123), Expect = 1e-06
Identities = 64/273 (23%), Positives = 99/273 (35%), Gaps = 28/273 (10%)
Query: 46 VCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCN 105
VC +D + G+ E P+V+GHE G V +G K TG GD V V V C +C
Sbjct: 6 VCHTDAYTLDGHDPEGLFPVVLGHEGSGIVESVG-KGVTGFAPGDHV-VPLYVPQCKECE 63
Query: 106 RCNNDNEQYCPKFVTTYSQPYFEDG-------------YVGQGGYASHIRVHEHFVIPIP 152
C N C K + + DG ++G ++ + V + + +
Sbjct: 64 YCKNPKTNMCQKIRVSQGDGFMPDGTSRFTCNGKQLFHFMGCSTFSEYTVVADISLCKVN 123
Query: 153 ESLETNNVAPLLCGGATVYSPLKRNXXXXXXXXXXXXXXXXXXXXXLL-AKAMGA-EVYA 210
V+ L CG +T Y + ++ AKA GA ++
Sbjct: 124 PQAPLEKVSLLGCGISTGYGAVLNTCKVEEGSTVAVWGLGAVGLAVIMGAKAAGAKKIVG 183
Query: 211 ISRSHAKEETSKQLGADHYIATED---------EGWETKYFD-TLDFMVLCGNSLSAVDF 260
I +K E +K GA I + + W + FD D+ C ++ +
Sbjct: 184 IDLIESKFEKAKMFGATECINPKSVELPEGKSFQSWLVEQFDGGFDYTFECIGNVHTMR- 242
Query: 261 GKLPKILKAQGVIASISVPDQHEAIHLHPAQLL 293
L K GV I V + I P QL+
Sbjct: 243 QALEAAHKGWGVSCIIGVAGAGQEIATRPFQLV 275
>SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 380
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 17/155 (10%)
Query: 32 FNPR--DVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGLKVG 89
F PR +V I+I GVC +D + G E P+++GHE G V +G + T ++VG
Sbjct: 33 FPPRVHEVRIKIVNSGVCHTDAYTLSGKDPEGLFPVILGHEGAGIVESVGPQVTT-VQVG 91
Query: 90 DRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFEDG-------------YVGQGG 136
D V + C C C + C + TT + DG ++G
Sbjct: 92 DPV-IALYTPECKTCKFCKSGKTNLCGRIRTTQGKGLMPDGTSRFSCNGNTLLHFMGCST 150
Query: 137 YASHIRVHEHFVIPIPESLETNNVAPLLCGGATVY 171
++ + V + V+ I ++V L CG T Y
Sbjct: 151 FSEYTVVADISVVAIERLAPLDSVCLLGCGITTGY 185
>SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 378
Score = 49.7 bits (117), Expect = 7e-06
Identities = 55/236 (23%), Positives = 92/236 (38%), Gaps = 21/236 (8%)
Query: 11 AVVDSHKKWLSPEKV-VYPAKQFNPRDVDIEIEACGVCGSDVHCAKGNWGEMKLPLVVGH 69
AV K+ LS E + V P K +V ++++ VC +D + G E P+V+GH
Sbjct: 13 AVAWGAKEPLSIEDIQVAPPKA---HEVRVKVDWSAVCHTDAYTLSGVDPEGAFPIVLGH 69
Query: 70 EIIGKVVRLGDKCDTGLKVGDRVGVGAQVSACLDCNRCNNDNEQYCPKFVTTYSQPYFED 129
E G V +G+ ++ GD V + C +C C + C K T + D
Sbjct: 70 EGAGIVESIGEGV-INVRPGDHV-ILLYTPECKECKFCRSGKTNLCSKIRETQGRGLMPD 127
Query: 130 G-------------YVGQGGYASHIRVHEHFVIPIPESLETNNVAPLLCGGATVYSPLKR 176
G Y+G ++ + V + ++ I S ++ L CG T + +
Sbjct: 128 GTSRFSCRDKTLLHYMGCSSFSQYTVVADISLVAISHSAPLRSICLLGCGVTTGFGAVTH 187
Query: 177 NXXXXXXXXXXXXXXXXXXXXXLL-AKAMGA-EVYAISRSHAKEETSKQLGADHYI 230
+ + A A GA + AI + KE +K+ GA +I
Sbjct: 188 SAKVESGSTVAVVGCGCVGLAAMQGAVAAGASRIIAIDINADKEVYAKKFGATDFI 243
>SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase
Length = 423
Score = 49.7 bits (117), Expect = 7e-06
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 33 NPRDVDIEIEACGVC-GSDVHCAKGNWGEMKLPLVVGHEIIGKVVRLGDKCDTGLKVGDR 91
+P+DV ++ AC +C GSD H G ++ ++GHE G V GD+ + L++GDR
Sbjct: 60 HPKDVIVKTTACTICSGSDSHIFSGEMPGIEKGAILGHESCGIVAEKGDEVN-NLEIGDR 118
Query: 92 VGVGAQVSACLDCNRCNNDNEQYC 115
V + + AC C+ C C
Sbjct: 119 VVIAFDL-ACGQCSFCKRHEYAAC 141
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,083,577
Number of Sequences: 60738
Number of extensions: 894638
Number of successful extensions: 1960
Number of sequences better than 1.0e-05: 42
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 1846
Number of HSP's gapped (non-prelim): 42
length of query: 366
length of database: 30,389,216
effective HSP length: 108
effective length of query: 258
effective length of database: 23,829,512
effective search space: 6148014096
effective search space used: 6148014096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)