ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5208 good Y KOG2086 Nuclear structure Protein tyrosine phosphatase SHP1/Cofactor for p97 ATPase-mediated vesicle membrane fusion
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5208 1785253 1784054 -400
(400 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBL058w [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor f... 361 1e-99
SPAC343.09 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofacto... 139 1e-32
Hs20149635 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofacto... 122 9e-28
7304214 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor f... 105 9e-23
At4g04210 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor... 96 1e-19
At4g22150 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor... 95 2e-19
At4g15410_1 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofact... 90 5e-18
Hs18552306 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofacto... 82 2e-15
CE27555 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor f... 82 2e-15
7291782_1 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor... 80 7e-15
Hs10047114 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofacto... 75 1e-13
>YBL058w [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 423
Score = 361 bits (926), Expect = 1e-99
Identities = 206/423 (48%), Positives = 261/423 (61%), Gaps = 32/423 (7%)
Query: 3 DEQIQQFVALTNTSVNVASDYLNQFGDLGEALNAFYATQQDEQEPKTK-ASFEQPIPKAA 61
DE IQQF+ALTN S N+A YL++FGDL EALN++YA+Q D+Q+ + + A + + KA
Sbjct: 6 DETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQTDDQKDRREEAHWNRQQEKAL 65
Query: 62 SQGELSNSSAKDDVTYART----------------LSGQKIALPRSTXXXXXXXXXXXXX 105
Q S +S+ + L + P T
Sbjct: 66 KQEAFSTNSSNKAINTEHVGGLCPKPGSSQGSNEYLKRKGSTSPEPTKGSSRSGSGNNSR 125
Query: 106 XXX-XDILKG---GDDEDEDRNTFAGGETSGLEITDPHANDSNSLIRDLLQKXXXXXXXX 161
D+++G DDED+ RNTFAGGETSGLE+TDP +D NSL++DLL+K
Sbjct: 126 FMSFSDMVRGQADDDDEDQPRNTFAGGETSGLEVTDP--SDPNSLLKDLLEKARRGGQMG 183
Query: 162 XXXXXXXXXXXSK-KHHFVGKGYRLGSDVSAXXXXXXXXXXXXSK-PKKVTREITFWKDG 219
+ F G+G+RLGS + A + P+KVTREITFWK+G
Sbjct: 184 AENGFRDDEDHEMGANRFTGRGFRLGSTIDAADEVVEDNTSQSQRRPEKVTREITFWKEG 243
Query: 220 FQVGDGKLYRYDDPENSFYLKELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKV 279
FQV DG LYRYDDP NSFYL ELNQGRAPL+LLDV+FGQEV+V VYKKL+E Y P RK+
Sbjct: 244 FQVADGPLYRYDDPANSFYLSELNQGRAPLKLLDVQFGQEVEVNVYKKLDESYKAPTRKL 303
Query: 280 SGFQGTGKRLGSPIPGDAVNSQSASPAESTPVGTEIKEKSPDDELK-GDTSVQIRYASGK 338
GF G G+RLGSPIPG+ +S + P TP E + PD+E K GDTS+QIRYA+GK
Sbjct: 304 GGFSGQGQRLGSPIPGE--SSPAEVPKNETPAAQE--QPMPDNEPKQGDTSIQIRYANGK 359
Query: 339 REVLRCNSTDTIRFLYQHV--KANTAEMRPFTLSHAFPVKPIDEFDSTLKDQDLCNAVVV 396
REVL CNSTDT++FLY+HV ANT R FTL++AFP+KPI ++TLKD DL N+VVV
Sbjct: 360 REVLHCNSTDTVKFLYEHVTSNANTDPSRNFTLNYAFPIKPISNDETTLKDADLLNSVVV 419
Query: 397 QRW 399
QRW
Sbjct: 420 QRW 422
>SPAC343.09 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 410
Score = 139 bits (349), Expect = 1e-32
Identities = 100/311 (32%), Positives = 149/311 (47%), Gaps = 33/311 (10%)
Query: 112 LKGGDDEDEDRN-TFAGGETSGLEITDPHANDSNSLIRDLLQKXXXXXXXXXXXXXXXXX 170
L+G D+ E+++ F GGE SGL + D + L+RD+L+K
Sbjct: 107 LEGNDESAEEKSHLFTGGEKSGLSVEDGDPDPKKQLVRDILEKARQHTISPLDEQDSGPS 166
Query: 171 XXSKKHHFVGKGYRLGSDVSAXXXXXXXXXX--------XXSKPKK-VTREITFWKDGFQ 221
+ VG+ RLG++ A S+P+K + R + FW++GF
Sbjct: 167 SLASSWASVGQ--RLGTENEASGSTTPVTQSGPPRENPPTESQPEKPLRRTLYFWRNGFS 224
Query: 222 VGDGKLYRYDDPENSFYLKELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKVSG 281
V DG +Y YDDP N L+ +N GRAPL LL V Q +DV V +++E YV P +
Sbjct: 225 VDDGPIYTYDDPANQEMLRYINSGRAPLHLLGVSMNQPIDVVVQHRMDEDYVAPFKP--- 281
Query: 282 FQGTGKRLG--------SPIPGDAVNSQSASPAESTPVGTEIKEKSPD-----DELKGDT 328
F G G+RLG S +PG S S S P+ + +P DE K T
Sbjct: 282 FSGKGQRLGSTYMQPRMSQMPGGLYTDTSTS--SSVPINVKPNSTTPHASLQIDENKPTT 339
Query: 329 SVQIRYASGKREVLRCNSTDTIRFLYQHVKANTAEMRPFTLSHAFPVKPIDEFDS-TLKD 387
+Q+R ++G R VL N + T+ +Y+ V+A F LS FP K +++ S T++
Sbjct: 340 RIQVRLSNGGRTVLTVNLSHTLHDIYEAVRA--VSPGNFILSVPFPAKTLEDDPSVTVEA 397
Query: 388 QDLCNAVVVQR 398
L NA +VQ+
Sbjct: 398 ASLKNASLVQK 408
>Hs20149635 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 370
Score = 122 bits (306), Expect = 9e-28
Identities = 113/406 (27%), Positives = 170/406 (41%), Gaps = 55/406 (13%)
Query: 4 EQIQQFVALTNTSVNVASDYLNQFG-DLGEALNAFYATQQDEQEPKTKASFEQPIPKAAS 62
E +++FVA+T + A +L G DL AL +FY DE + Q P + S
Sbjct: 7 EALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDI----VTISQATPSSVS 62
Query: 63 QGELSNSSAKDDVTYARTLSGQKIALPRSTXXXXXXXXXXXXXXXXXDILKGGDDEDEDR 122
+G + + + VT R L + ++E+E +
Sbjct: 63 RG---TAPSDNRVTSFRDLIHDQ---------------------------DEDEEEEEGQ 92
Query: 123 NTFAGG-ETSGLEITDPHANDS-NSLIRDLLQKXXXXXXXXXXXXXXXXXXXSKKHHFVG 180
+AGG E SG +I P S N L+ DL + SK F G
Sbjct: 93 RFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAG 152
Query: 181 KGYRLGSDVSAXXXXXXXXXXXXSKPKKVTREITFWKDGFQVGDGKLYRYDDPENSFYLK 240
GYRLG+ S + V + WK GF + +G+L Y DP N+ +L+
Sbjct: 153 GGYRLGAAPEEESAYVAGEKRQHSS-QDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLE 211
Query: 241 ELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKVSGFQGTGKRLGSPIPGDAVNS 300
+ +G P +L + G +V++ + +E +V PK F G G++LGS P S
Sbjct: 212 SIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTS 271
Query: 301 QSASPAESTPVGTEIKEKSP--DDELKGDTSVQIRYASGKREVLRCNSTDTIRFLYQHVK 358
A AE+ E K S DE + T++QIR A G R V + N + I ++
Sbjct: 272 SPAQQAEN-----EAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSHRI----SDIR 322
Query: 359 ANTAEMRP------FTLSHAFPVKPIDEFDSTLKDQDLCNAVVVQR 398
+ RP F L FP K + + TLK+ +L NAV+VQR
Sbjct: 323 LFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNAVIVQR 368
>7304214 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 407
Score = 105 bits (263), Expect = 9e-23
Identities = 100/407 (24%), Positives = 169/407 (40%), Gaps = 23/407 (5%)
Query: 6 IQQFVALTNTSVNVASDYLNQFG-DLGEALNAFYATQQDEQEP-KTKASFEQPIPKAASQ 63
I QF+ +T T NVA YL+ D+ AL +++TQ D P T + P PK S
Sbjct: 8 IAQFIEITGTDENVARFYLSSCDWDIEHALGNYWSTQADLPVPVPTVGHADNPKPKPTSS 67
Query: 64 GELSNSSAKDDVTYARTLSGQKIALPRSTXXXXXXXXXXXXXXXXXDILKGGDDEDEDRN 123
S S++ T ++ S D+ K +D+ +
Sbjct: 68 SGASASASAAGAT--KSADSAVATSSASVDIAPAATKAKPKFATLSDMSKESSSDDDQQA 125
Query: 124 TFAGG-ETSGLEITDPHANDS-NSLIRDLLQKXXXXXXXXXXXXXXXXXXXSKKHHFV-G 180
+AGG + SG ++ P + + D+++ V G
Sbjct: 126 FYAGGSDRSGQQVLGPPKRKNFREQLTDMMRSAQEQNIAEVGPSTSSGSASGGSGGAVWG 185
Query: 181 KGYRLGSDVSAXXXXXXXXXXXXSKPKKVTREITFWKDGFQVGDGKLYRYDDPENSFYLK 240
+G RLG + + K V + W GF + G+L YDDP+N +L+
Sbjct: 186 QGMRLGMTDNDHTAVGTKKPAATIENKPVV-VLKLWSQGFSIDGGELRHYDDPQNKEFLE 244
Query: 241 ELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRK--VSGFQGTGKRLGSPIPGDAV 298
+ +G P +LL E G+ V+V V E + KR+ F+G+G++LGSP+ + V
Sbjct: 245 TVMRGEIPQELL--EMGRMVNVDVEDHRHEDF---KRQPVPQTFKGSGQKLGSPV-ANLV 298
Query: 299 NSQSASPAESTPVGTEIKEKSPDDELK-----GDTSVQIRYASGKREVLRCNSTDTIRFL 353
P +P +E S D + T++QIR A G R + N + T+ +
Sbjct: 299 TEAPTVPVALSPGEAANQEASARDAINLNSEAPSTTLQIRLADGSRLAAQFNLSHTVSDI 358
Query: 354 YQHVKANTAEMRP--FTLSHAFPVKPIDEFDSTLKDQDLCNAVVVQR 398
+ ++ + F L +FP + + + +ST++ L NA ++QR
Sbjct: 359 RRFIQTARPQYSTSNFILVSSFPTRELSDDNSTIEKAGLKNAALMQR 405
>At4g04210 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 308
Score = 95.5 bits (236), Expect = 1e-19
Identities = 78/300 (26%), Positives = 127/300 (42%), Gaps = 31/300 (10%)
Query: 113 KGGDDEDED----RNTFAGGETSGLEITDPHANDSNSLIRDLLQKXXXXXXXXXXXXXXX 168
+ G D D D + + GGE SG+ + DP D I + ++
Sbjct: 27 RSGPDSDSDSDGPQEYYTGGEKSGMLVQDPSKKDDVDEIFNQARQLGAVEGPLEPP---- 82
Query: 169 XXXXSKKHHFVGKGYRLGSDVSAXXXXXXXXXXXXSKPKKVTREITFWKDGFQVGDGKLY 228
F G G L + +P+ V I FW +GF + DG L
Sbjct: 83 ----PSSRSFTGTGRLLSGE---------NVPTGNQQPEPVVHNIVFWSNGFTIDDGPLR 129
Query: 229 RYDDPENSFYLK-----ELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKVSGFQ 283
+ DDPEN+ +L+ + + P +L + V V + +K E+ KR+VS FQ
Sbjct: 130 KLDDPENASFLEVNDFHSIRKSECPKELEPADRRAPVHVNLMRKEEKCPERQKRRVS-FQ 188
Query: 284 GTGKRLGSPIPGDAVNSQSASPAESTPVGTE--IKEKSPDDELKGDTSVQIRYASGKREV 341
G G+ LG G +S A + P+ TE + DE TS+Q+R A G R V
Sbjct: 189 GVGRTLGGSNEGSGSSSPVAPDSAPIPIQTEPAPSQSLVIDETVPTTSIQLRLADGTRLV 248
Query: 342 LRCNSTDTIRFLYQHVKANT--AEMRPFTLSHAFPVKPIDEFDSTLKDQDLCNAVVVQRW 399
+ N T+ + + ++ A + + FP KP+ + T+++ L N+VV+Q++
Sbjct: 249 AKFNHHHTVNDIRGFIDSSRPGASLNYQLQTMGFPPKPLTDLTQTIEEAGLANSVVLQKF 308
>At4g22150 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 302
Score = 94.7 bits (234), Expect = 2e-19
Identities = 76/287 (26%), Positives = 124/287 (42%), Gaps = 24/287 (8%)
Query: 117 DEDEDRNTFAGGETSGLEITDPHANDSNSLIRDLLQKXXXXXXXXXXXXXXXXXXXSKKH 176
D D + F GGE SG+ + DP + + ++ + S
Sbjct: 36 DSDGPQEYFTGGEKSGMLVQDPTKEPKHDDVDEIFNQARQLGAVEGPLEHP-----SSSR 90
Query: 177 HFVGKGYRLGSDVSAXXXXXXXXXXXXSKPKKVTREITFWKDGFQVGDGKLYRYDDPENS 236
F G G L + +P+ V I FW +GF V DG L + DDPEN+
Sbjct: 91 SFTGTGRLLSGE---------SVPTALQQPEPVIHNIIFWSNGFTVDDGPLRKLDDPENA 141
Query: 237 FYLKELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKVSGFQGTGKRLGSPIPGD 296
+L + + P +L V+ V V + ++ E+ K KVS FQG G+ LG
Sbjct: 142 SFLDSIRKSECPKELEPVDKRAPVHVNLMRRDEKCPEKEKLKVS-FQGVGRTLGG----- 195
Query: 297 AVNSQSASPAESTPVGT--EIKEKSPDDELKGDTSVQIRYASGKREVLRCNSTDTIRFLY 354
A +S ++S + T V + DE TS+Q+R A G R V + N+ T+ +
Sbjct: 196 ASSSTASSQSNLTDVAAVQSPLQSLVVDETLPSTSIQLRLADGTRMVAKFNNHHTVNDIR 255
Query: 355 QHVK-ANTAEMRPFTLS-HAFPVKPIDEFDSTLKDQDLCNAVVVQRW 399
++ + +TL FP KP+ + T++ L ++VV+Q++
Sbjct: 256 GFIEFSRPGNPNNYTLQVMGFPPKPLTDPSQTIEQAGLASSVVIQKF 302
>At4g15410_1 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 463
Score = 90.1 bits (222), Expect = 5e-18
Identities = 74/280 (26%), Positives = 115/280 (40%), Gaps = 29/280 (10%)
Query: 115 GDDEDEDRNTFAGGETSGLEITDPH-ANDSNSLIRDLLQKXXXXXXXXXXXXXXXXXXXS 173
G D DE + GG+ SG+ + DP D + L Q +
Sbjct: 150 GSDSDEANEYYTGGQKSGMMVQDPKKVKDVDELFDQARQSAVDRPVEPSRSASTSFTGAA 209
Query: 174 KKHHFVGKGYRLGSDVSAXXXXXXXXXXXXSKPKKVTREITFWKDGFQVGDGKLYRYDDP 233
+ +S +P+++ ITFW +GF V DG L + DP
Sbjct: 210 RL-------------LSGEAVSSSPQQQQQEQPQRIMHTITFWLNGFTVNDGPLRGFSDP 256
Query: 234 ENSFYLKELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKVSGFQGTGKRLGSPI 293
EN+ ++ +++ P +L + V V + ++ E PPK K + FQG G+ LG+
Sbjct: 257 ENAAFMNSISRSECPSELEPADKKIPVHVDLVRRGENFTEPPKPK-NPFQGVGRTLGASG 315
Query: 294 PGDAVNSQSASPAESTPVGTEIKEKSPDDELKGD-----TSVQIRYASGKREVLRCNSTD 348
G S SA A S P+ +P L D TS+Q+R A G R V R N+
Sbjct: 316 SG----SSSAPQASSAPMNV---APAPSRGLVVDPAAPTTSIQLRLADGTRLVSRFNNHH 368
Query: 349 TIRFLYQHVKANT--AEMRPFTLSHAFPVKPIDEFDSTLK 386
T+R + + A+ L+ FP K + E D T++
Sbjct: 369 TVRDVRGFIDASRPGGSKEYQLLTMGFPPKQLTELDQTIE 408
>Hs18552306 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 259
Score = 81.6 bits (200), Expect = 2e-15
Identities = 62/195 (31%), Positives = 95/195 (47%), Gaps = 10/195 (5%)
Query: 207 KKVTREITFWKDGFQVGDGKLYRYDDPENSFYLKELNQGRAPLQLLDVEFGQEVDVTVYK 266
K+V I WK+GF V D Y D + +L + +G P +L + +EVDV V
Sbjct: 59 KQVDVNIKLWKNGFTVNDD-FRSYSDGASQQFLNSIKKGELPSELQGIFDKEEVDVKVED 117
Query: 267 KLEEPYVPPKRKVSGFQGTGKRLGSPIPGDAVNSQSASPAESTPVGTEIKEKS-PDDELK 325
K E + K F G G RLGS P + S A++ V + + P + L+
Sbjct: 118 KKNEICLSTKPVFQPFSGQGHRLGSATP------KIVSKAKNIEVENKNNLSAVPLNNLE 171
Query: 326 GDTSVQIRYASGKREVLRCNSTDTIRFLYQHVKANTAEMR--PFTLSHAFPVKPIDEFDS 383
T++QI A+GKR V + N T + + ++ R PF+L+ A PV + +
Sbjct: 172 PITNIQIWLANGKRIVQKFNITHRVSHIKDFIEKYQGSQRSPPFSLATALPVLRLLDETL 231
Query: 384 TLKDQDLCNAVVVQR 398
TL++ DL NAV++QR
Sbjct: 232 TLEEADLQNAVIIQR 246
>CE27555 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 301
Score = 81.6 bits (200), Expect = 2e-15
Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 26/208 (12%)
Query: 209 VTREITFWKDGFQVGDGKLYRYDDPENSFYLKELNQGRAPLQLLDVEFGQEVDVTVYKKL 268
++ + W DG + DG L DP +L+ + +G P L+ G+E+D V +
Sbjct: 90 ISLTLHLWSDGLSIEDGPLMSRQDPRTIEFLESVGKGEIPPSLVQQYPGKEIDFKVNRHH 149
Query: 269 EEPYVPPKRKVSGFQGTGKRLGSPIPGDAVNSQSASPAESTPVGTEIKEKSPDDELKGD- 327
EE YV PK K F G+G RLG+ +P V QS+S A + + + +PD + +
Sbjct: 150 EE-YVAPKMK--PFGGSGVRLGNVVP--TVLGQSSSSATTAGTSSATTDHNPDHTAENEA 204
Query: 328 ------------------TSVQIRYASGKREVLRCNSTDTIRFLYQHVKANTAEM--RPF 367
T++QIR + +R V N + T+ + + +M PF
Sbjct: 205 KQLEDAKKELSTNMNEPTTNIQIRLPNNQRLVGIFNHSHTLEAVRTFICTARPDMIYAPF 264
Query: 368 TLSHAFPVKPIDEFDSTLKDQDLCNAVV 395
+ A+P KP ++ TLKD ++ N+VV
Sbjct: 265 QMMAAYPPKPFEDESQTLKDANVLNSVV 292
>7291782_1 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 788
Score = 79.7 bits (195), Expect = 7e-15
Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 21/224 (9%)
Query: 180 GKGYRLGSDVSAXXXXXXXXXXXXSKPKKVTREIT---FWKDGFQVGDGKLYRYDDPENS 236
G G RLGS ++P I W +GF + DG L Y PEN
Sbjct: 125 GHGNRLGSAHPINPPPRSATEDSDTEPADDEHTIVVLHLWSEGFSLDDGSLRLYALPENE 184
Query: 237 FYLKELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKVSGFQGTGKRLGSPIPGD 296
+L+ + +G P ++L V V ++V E Y RK F G G+ L SP P
Sbjct: 185 RFLRAILRGDFPEEMLRV---PRVQLSVQDHTNESYRHLSRK--QFMGPGRPLNSPSPQI 239
Query: 297 AVNSQSASPAESTPVGTEIKEKSPDDELKGDTSVQIRYASGKREVLRCNSTDTIRFLYQH 356
V P G ++ E++ T+VQ+R A G R R N T + LYQ+
Sbjct: 240 LV----VGPMPVEAQGLQLNERA------DTTTVQLRMADGSRVAGRFNLTHNVGDLYQY 289
Query: 357 VKANTAEM--RPFTLSHAFPVKPIDEFDS-TLKDQDLCNAVVVQ 397
+ E R F L AFP + + E D+ TL +LCN VV+Q
Sbjct: 290 ARLARPEFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQ 333
>Hs10047114 [Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97
ATPase-mediated vesicle membrane fusion
Length = 371
Score = 75.5 bits (184), Expect = 1e-13
Identities = 102/408 (25%), Positives = 156/408 (38%), Gaps = 62/408 (15%)
Query: 6 IQQFVALTNTSVNVASDYLNQFG-DLGEALNAFYATQQDEQEPKTKASFEQPIPKAASQG 64
+++FVA+T + A +L G DL AL Y DE + Q P + S+G
Sbjct: 9 LREFVAVTGAEEDRARFFLESAGWDLQIALEPSYEDGGDEDI----VTISQATPSSVSRG 64
Query: 65 ELSNSSAKDDVTYARTLSGQKIALPRSTXXXXXXXXXXXXXXXXXDILKGGDDEDEDRNT 124
+ + + VT R L D + ++E+ R+
Sbjct: 65 ---TAPSDNRVTSFRDL--------------------------IHDQDEDEEEEEGQRSR 95
Query: 125 F--AGGETSGLEITDPHANDS-NSLIRDLLQ--KXXXXXXXXXXXXXXXXXXXSKKHHFV 179
F G E SG +I P S N L+ DL + K SK ++
Sbjct: 96 FYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVACWKRVTQEPWGETSKPRPYL 155
Query: 180 -GKGYRLGSDVSAXXXXXXXXXXXXSKPKKVTREITFWKDGFQVGDGKLYRYDDPENSFY 238
G GY LG + + + WK G+ + +G L Y F+
Sbjct: 156 QGGGYPLGPAPEEDSFLLLAGEKRQHFQQDGSCSMKLWKSGYSLDNGDLRSYKPSNAQFW 215
Query: 239 LKELNQGRAPLQLLDVEFGQEVDVTVYKKLEEPYVPPKRKVSGFQGTGKRLGSPIPGDAV 298
+G + ++ L V++ + +E +V PK F G G++LGS P
Sbjct: 216 --SYRRGESTIRRLATV---TVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLS 270
Query: 299 NSQSASPAESTPVGTEIKEKSPD--DELKGDTSVQIRYASGKREVLRCNSTDTIRFLYQH 356
S A AE+ E K S DE + T++QIR A G R V + N + I
Sbjct: 271 TSSPAQQAEN-----EAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSHRI----SD 321
Query: 357 VKANTAEMRP------FTLSHAFPVKPIDEFDSTLKDQDLCNAVVVQR 398
++ + RP F L FP K + + TLK+ +L NAV+VQR
Sbjct: 322 IRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNAVIVQR 369
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.131 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,112,187
Number of Sequences: 60738
Number of extensions: 917796
Number of successful extensions: 2196
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2156
Number of HSP's gapped (non-prelim): 14
length of query: 400
length of database: 30,389,216
effective HSP length: 109
effective length of query: 291
effective length of database: 23,768,774
effective search space: 6916713234
effective search space used: 6916713234
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)