ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5297 good FE KOG1448 Amino acid transport and metabolism Ribose-phosphate pyrophosphokinase
r_klactV5297 good FE KOG1448 Nucleotide transport and metabolism Ribose-phosphate pyrophosphokinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5297 1813948 1812977 -324
(324 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER099c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 551 e-157
YBL068w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 543 e-154
SPCC1620.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 423 e-118
YHL011c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 406 e-113
Hs4506127 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 384 e-107
Hs4506129 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 384 e-106
7294893 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 384 e-106
CE27199 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 373 e-103
CE00745 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 373 e-103
Hs20539448 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 372 e-103
7294894 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 370 e-102
CE29454 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 369 e-102
SPBC3D6.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 273 2e-73
Hs4506133 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-as... 247 1e-65
At2g35390 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 240 2e-63
At1g32380 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 237 2e-62
Hs4506131 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-as... 228 9e-60
At2g44530 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 226 5e-59
CE03789 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-asso... 216 4e-56
SPAC4A8.14 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 208 1e-53
YKL181w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 207 1e-53
7301964 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-asso... 192 4e-49
YOL061w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 135 8e-32
Hs20542182 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 77 3e-14
At1g10700 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 72 1e-12
At2g42910 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 69 7e-12
>YER099c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 551 bits (1421), Expect = e-157
Identities = 275/318 (86%), Positives = 299/318 (93%)
Query: 7 MSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQT 66
MSTNSIKLLAGNSHP LA+ I++ LG+ LS +GVYQYSN+ETSVTIGESIRDEDVYIIQT
Sbjct: 1 MSTNSIKLLAGNSHPGLAELISQRLGVPLSKVGVYQYSNKETSVTIGESIRDEDVYIIQT 60
Query: 67 GTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQML 126
G GE EINDFLMELLI+IHAC+TAS RRITAVIPNFPYARQDKKDKSRAPITAKL+A +L
Sbjct: 61 GYGEHEINDFLMELLILIHACKTASVRRITAVIPNFPYARQDKKDKSRAPITAKLIANLL 120
Query: 127 ETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKTDIGNAILVSPDAGGAKR 186
ETAGCDHVITMDLHASQIQGFFHIPVDNLY EPSVL YI+ KTD NAILVSPDAGGAKR
Sbjct: 121 ETAGCDHVITMDLHASQIQGFFHIPVDNLYGEPSVLNYIRTKTDFNNAILVSPDAGGAKR 180
Query: 187 VASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLL 246
VASLADKLD+NFALIHKERQKANEVSRM+LVGDV GKSCLLIDDMADTCGTLVKA DTL+
Sbjct: 181 VASLADKLDMNFALIHKERQKANEVSRMLLVGDVAGKSCLLIDDMADTCGTLVKACDTLM 240
Query: 247 EHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVNILDQIDISPTLAEAI 306
+HGAKEV+AIVTHGIFSGSA +KL NS+LSRIVCTNTVPVDLD++I+DQ+DISPT+AEAI
Sbjct: 241 DHGAKEVIAIVTHGIFSGSAREKLINSRLSRIVCTNTVPVDLDLDIVDQVDISPTIAEAI 300
Query: 307 RRLHNGESVSYLFTHAAI 324
RRLHNGESVSYLFTHA +
Sbjct: 301 RRLHNGESVSYLFTHAPV 318
>YBL068w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 355
Score = 543 bits (1400), Expect = e-154
Identities = 273/324 (84%), Positives = 300/324 (92%), Gaps = 1/324 (0%)
Query: 2 ETSKRMSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDV 61
E+ + M+ NSIKLLAGNSHP+LA+ I++ LG+ LS +GVYQYSN+ETSVTIGES+RDEDV
Sbjct: 32 ESREDMAINSIKLLAGNSHPDLAEQISKKLGIPLSKVGVYQYSNKETSVTIGESLRDEDV 91
Query: 62 YIIQTGTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKL 121
YIIQTG GEQEINDFLMELLI+IHAC+ ASAR+IT VIPNFPYARQDKKDKSRAPITAKL
Sbjct: 92 YIIQTGIGEQEINDFLMELLILIHACQIASARKITTVIPNFPYARQDKKDKSRAPITAKL 151
Query: 122 VAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQ-HKTDIGNAILVSPD 180
VA +L+TAG DHVITMDLHASQIQGFFHIPVDNLYAEPSVL YI+ KTD NAILVSPD
Sbjct: 152 VANLLQTAGADHVITMDLHASQIQGFFHIPVDNLYAEPSVLNYIRARKTDFDNAILVSPD 211
Query: 181 AGGAKRVASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVK 240
AGGAKRVA+LADKLDLNFALIHKERQKANEVS+MVLVGDVT KSCLL+DDMADTCGTLVK
Sbjct: 212 AGGAKRVAALADKLDLNFALIHKERQKANEVSKMVLVGDVTNKSCLLVDDMADTCGTLVK 271
Query: 241 ASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVNILDQIDISP 300
A DTL+EHGAKEV+AIVTHGIFSGSA +KL+NS+LSRIVCTNTVPVDLD+ I DQIDISP
Sbjct: 272 ACDTLMEHGAKEVIAIVTHGIFSGSAREKLRNSRLSRIVCTNTVPVDLDLPIADQIDISP 331
Query: 301 TLAEAIRRLHNGESVSYLFTHAAI 324
T AEAIRRLHNGESVSYLFTHA +
Sbjct: 332 TFAEAIRRLHNGESVSYLFTHAPV 355
>SPCC1620.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 321
Score = 423 bits (1087), Expect = e-118
Identities = 217/321 (67%), Positives = 264/321 (81%), Gaps = 7/321 (2%)
Query: 7 MSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQT 66
M++NSIK+ AGNSHPELA+ +AR +GL L + V QYSN+ETSVTIGES+RDEDV+I+QT
Sbjct: 1 MASNSIKIFAGNSHPELAEKVARRIGLSLGKVAVVQYSNRETSVTIGESVRDEDVFILQT 60
Query: 67 GTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQML 126
G G IND LMELLI+I+ACR+ASARRITA+IP FPYARQDKKDKSRAPITA+LVA ML
Sbjct: 61 GCGS--INDHLMELLIMINACRSASARRITAIIPCFPYARQDKKDKSRAPITARLVANML 118
Query: 127 ETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKTD--IGNAILVSPDAGGA 184
+TAGC+H+ITMDLHASQIQGFF++PVDNLYAEPSVL+YI+ D + ++VSPDAGGA
Sbjct: 119 QTAGCNHIITMDLHASQIQGFFNVPVDNLYAEPSVLRYIRENIDTTVNPTVIVSPDAGGA 178
Query: 185 KRVASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDT 244
KR +LAD+LDL+FALIHKERQKANEVSRMVLVGDV K +L+DDMADTCGTL A+ T
Sbjct: 179 KRATALADRLDLDFALIHKERQKANEVSRMVLVGDVRDKLAILVDDMADTCGTLGLAAKT 238
Query: 245 LLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVNI---LDQIDISPT 301
L ++GAK V AIVTHGI SG A + + S L +++ TNT+P D ++ ++ IDIS
Sbjct: 239 LKDNGAKAVYAIVTHGILSGKAIKVINESALEKVIVTNTIPHDDKRSLCSKIETIDISGV 298
Query: 302 LAEAIRRLHNGESVSYLFTHA 322
LAE IRR+H+GESVS LF+ A
Sbjct: 299 LAECIRRIHHGESVSVLFSVA 319
>YHL011c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 320
Score = 406 bits (1044), Expect = e-113
Identities = 208/316 (65%), Positives = 258/316 (80%), Gaps = 4/316 (1%)
Query: 7 MSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQT 66
M TNSIKLLA + H LA+ +A+ LGL+L++ + + E S +IGES+RD+D++II T
Sbjct: 1 MPTNSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFII-T 59
Query: 67 GTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQML 126
G +ND ++ELLI+I+A +TASARRITA+IPNFPYARQD+KDKSRAPITAKL+A ML
Sbjct: 60 QIGSGVVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADML 119
Query: 127 ETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKTDIGNAILVSPDAGGAKR 186
TAGCDHVITMDLHASQIQGFF +PVDNLYAEPSV++YI+ + ++I++SPDAGGAKR
Sbjct: 120 TTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNYMDSIIISPDAGGAKR 179
Query: 187 VASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLL 246
A+LAD+LDLNFALIHKER +ANEVSRMVLVGDVT K C+++DDMADTCGTL KA++ LL
Sbjct: 180 AATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILL 239
Query: 247 EHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVN---ILDQIDISPTLA 303
E+ AK V+AIVTHG+ SG A + + NSKL R+VCTNTVP + + L IDIS LA
Sbjct: 240 ENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLA 299
Query: 304 EAIRRLHNGESVSYLF 319
E+IRRLHNGES+SYLF
Sbjct: 300 ESIRRLHNGESISYLF 315
>Hs4506127 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 384 bits (987), Expect = e-107
Identities = 201/318 (63%), Positives = 247/318 (77%), Gaps = 6/318 (1%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
+IK+ +G+SH +L+Q IA LGL L + ++SNQET V IGES+R EDVYI+Q+G GE
Sbjct: 3 NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGE 62
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAG 130
IND LMELLI+I+AC+ ASA R+TAVIP FPYARQDKKDKSRAPI+AKLVA ML AG
Sbjct: 63 --INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 120
Query: 131 CDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAILVSPDAGGAKRVAS 189
DH+ITMDLHASQIQGFF IPVDNLYAEP+VLK+I+ ++ N +VSPDAGGAKRV S
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS 180
Query: 190 LADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHG 249
+AD+L+++FALIHKER+KANEV RMVLVGDV + +L+DDMADTCGT+ A+D LL G
Sbjct: 181 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG 240
Query: 250 AKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVD---LDVNILDQIDISPTLAEAI 306
A V AI+THGIFSG A ++ N+ +V TNT+P + + + IDIS LAEAI
Sbjct: 241 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI 300
Query: 307 RRLHNGESVSYLFTHAAI 324
RR HNGESVSYLF+H +
Sbjct: 301 RRTHNGESVSYLFSHVPL 318
>Hs4506129 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 384 bits (985), Expect = e-106
Identities = 201/318 (63%), Positives = 246/318 (77%), Gaps = 6/318 (1%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
+I L +G+SH +L+Q +A LGL L + ++SNQETSV IGES+R EDVYIIQ+G GE
Sbjct: 3 NIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGE 62
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAG 130
IND LMELLI+I+AC+ AS+ R+TAVIP FPYARQDKKDKSRAPI+AKLVA ML AG
Sbjct: 63 --INDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 120
Query: 131 CDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAILVSPDAGGAKRVAS 189
DH+ITMDLHASQIQGFF IPVDNLYAEP+VL++I+ + N I+VSPDAGGAKRV S
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTS 180
Query: 190 LADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHG 249
+AD+L++ FALIHKER+KANEV RMVLVGDV + +L+DDMADTCGT+ A+D LL G
Sbjct: 181 IADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG 240
Query: 250 AKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVD---LDVNILDQIDISPTLAEAI 306
A +V AI+THGIFSG A ++ N+ +V TNT+P + + IDIS LAEAI
Sbjct: 241 ATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAI 300
Query: 307 RRLHNGESVSYLFTHAAI 324
RR HNGESVSYLF+H +
Sbjct: 301 RRTHNGESVSYLFSHVPL 318
>7294893 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 384 bits (985), Expect = e-106
Identities = 200/315 (63%), Positives = 247/315 (77%), Gaps = 6/315 (1%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
+IK+ +G SHP+LAQ I LG+ L + ++SN ET V IGES+R EDVYI+Q+G+GE
Sbjct: 3 NIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGE 62
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAG 130
IND LMELLI+I+AC+ ASA R+TAVIP FPYARQDKKDKSRAPI+AKLVA ML AG
Sbjct: 63 --INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 120
Query: 131 CDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAILVSPDAGGAKRVAS 189
DH+ITMDLHASQIQGFF IPVDNLYAEP+VLK+I+ + N+I+VSPDAGGAKRV S
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVTS 180
Query: 190 LADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHG 249
+AD+L++ FALIHKER+KANEV+ MVLVGDV K +L+DDMADTCGT+V A+D L+E G
Sbjct: 181 IADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAG 240
Query: 250 AKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVD---LDVNILDQIDISPTLAEAI 306
A +V AI+THGIFSG A ++ N+ +V TNT+P D D + ID+S AEA+
Sbjct: 241 ATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAV 300
Query: 307 RRLHNGESVSYLFTH 321
RR HNGESVSYLF++
Sbjct: 301 RRTHNGESVSYLFSN 315
>CE27199 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 419
Score = 373 bits (957), Expect = e-103
Identities = 197/320 (61%), Positives = 245/320 (76%), Gaps = 10/320 (3%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
+IK+ +G+SHP+L+ I L L +S + ++SN+ET+V IGES+R EDVYIIQ+ GE
Sbjct: 103 NIKVFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYIIQSAAGE 162
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAG 130
IND LMELLI+I+AC+ AS+ R+ AVIP FPYARQDKKDKSRAPI+AKLVA ML AG
Sbjct: 163 --INDNLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAG 220
Query: 131 CDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKTDIGN---AILVSPDAGGAKRV 187
DH+ITMDLHASQIQGFF IPVDNLYAEP++LKYI K I N +++VSPDAGGAKRV
Sbjct: 221 ADHIITMDLHASQIQGFFDIPVDNLYAEPAILKYI--KESIPNWQTSVIVSPDAGGAKRV 278
Query: 188 ASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLE 247
S+AD+L+++FALIHKE ++ANEV +M LVG V GK +L+DDMADTCGT+ A+D L+E
Sbjct: 279 TSIADRLNVDFALIHKESKRANEVEKMTLVGSVEGKVAILVDDMADTCGTICMAADKLVE 338
Query: 248 HGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDV---NILDQIDISPTLAE 304
GA +V A HGIFSG A +L SK +V TNT+P D ++ + + IDIS LAE
Sbjct: 339 AGADKVYAFCVHGIFSGPALTRLNASKFEAVVVTNTIPQDENMKKCSKIQCIDISMILAE 398
Query: 305 AIRRLHNGESVSYLFTHAAI 324
AIRR HNGESVSYLF+H I
Sbjct: 399 AIRRTHNGESVSYLFSHVPI 418
>CE00745 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 377
Score = 373 bits (957), Expect = e-103
Identities = 197/320 (61%), Positives = 245/320 (76%), Gaps = 10/320 (3%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
+IK+ +G+SHP+L+ I L L +S + ++SN+ET+V IGES+R EDVYIIQ+ GE
Sbjct: 61 NIKVFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYIIQSAAGE 120
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAG 130
IND LMELLI+I+AC+ AS+ R+ AVIP FPYARQDKKDKSRAPI+AKLVA ML AG
Sbjct: 121 --INDNLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAG 178
Query: 131 CDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKTDIGN---AILVSPDAGGAKRV 187
DH+ITMDLHASQIQGFF IPVDNLYAEP++LKYI K I N +++VSPDAGGAKRV
Sbjct: 179 ADHIITMDLHASQIQGFFDIPVDNLYAEPAILKYI--KESIPNWQTSVIVSPDAGGAKRV 236
Query: 188 ASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLE 247
S+AD+L+++FALIHKE ++ANEV +M LVG V GK +L+DDMADTCGT+ A+D L+E
Sbjct: 237 TSIADRLNVDFALIHKESKRANEVEKMTLVGSVEGKVAILVDDMADTCGTICMAADKLVE 296
Query: 248 HGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDV---NILDQIDISPTLAE 304
GA +V A HGIFSG A +L SK +V TNT+P D ++ + + IDIS LAE
Sbjct: 297 AGADKVYAFCVHGIFSGPALTRLNASKFEAVVVTNTIPQDENMKKCSKIQCIDISMILAE 356
Query: 305 AIRRLHNGESVSYLFTHAAI 324
AIRR HNGESVSYLF+H I
Sbjct: 357 AIRRTHNGESVSYLFSHVPI 376
>Hs20539448 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 372 bits (956), Expect = e-103
Identities = 197/318 (61%), Positives = 243/318 (75%), Gaps = 6/318 (1%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
+IK+ +G+SH +L+Q IA LGL L + ++SNQET V I ES+R EDVYI+Q+G GE
Sbjct: 3 NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGE 62
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAG 130
IND LMELLI+I+AC+ ASA R+TAVIP FPYARQDKKDKSR+PI+AKLVA ML AG
Sbjct: 63 --INDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAG 120
Query: 131 CDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAILVSPDAGGAKRVAS 189
DH+ITMDLHASQIQGFF IPVDNLYAEP+VLK+I+ + N I+VSPDAGGAKRV S
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTS 180
Query: 190 LADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHG 249
+AD+L+++FALIHKER+KANEV +VLVGDV + +L+DDMADTC T+ A+D LL G
Sbjct: 181 IADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAG 240
Query: 250 AKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVNILDQ---IDISPTLAEAI 306
A V AI+THGIFSG A ++ + +V TNT+P D + + IDIS LAEAI
Sbjct: 241 ATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAI 300
Query: 307 RRLHNGESVSYLFTHAAI 324
RR HNGESVSYLF+H +
Sbjct: 301 RRTHNGESVSYLFSHVPL 318
>7294894 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 341
Score = 370 bits (951), Expect = e-102
Identities = 200/338 (59%), Positives = 247/338 (72%), Gaps = 29/338 (8%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
+IK+ +G SHP+LAQ I LG+ L + ++SN ET V IGES+R EDVYI+Q+G+GE
Sbjct: 3 NIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGE 62
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDK------------------ 112
IND LMELLI+I+AC+ ASA R+TAVIP FPYARQDKKDK
Sbjct: 63 --INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNY 120
Query: 113 -----SRAPITAKLVAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQH 167
SRAPI+AKLVA ML AG DH+ITMDLHASQIQGFF IPVDNLYAEP+VLK+I+
Sbjct: 121 DWKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKE 180
Query: 168 KT-DIGNAILVSPDAGGAKRVASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCL 226
+ N+I+VSPDAGGAKRV S+AD+L++ FALIHKER+KANEV+ MVLVGDV K +
Sbjct: 181 NIPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAI 240
Query: 227 LIDDMADTCGTLVKASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPV 286
L+DDMADTCGT+V A+D L+E GA +V AI+THGIFSG A ++ N+ +V TNT+P
Sbjct: 241 LVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQ 300
Query: 287 D---LDVNILDQIDISPTLAEAIRRLHNGESVSYLFTH 321
D D + ID+S AEA+RR HNGESVSYLF++
Sbjct: 301 DGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSN 338
>CE29454 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 369 bits (947), Expect = e-102
Identities = 195/317 (61%), Positives = 242/317 (75%), Gaps = 10/317 (3%)
Query: 14 LLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGEQEI 73
+ +G+SHP+L+ I L L +S + ++SN+ET+V IGES+R EDVYIIQ+ GE I
Sbjct: 5 VFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYIIQSAAGE--I 62
Query: 74 NDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAGCDH 133
ND LMELLI+I+AC+ AS+ R+ AVIP FPYARQDKKDKSRAPI+AKLVA ML AG DH
Sbjct: 63 NDNLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAGADH 122
Query: 134 VITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKTDIGN---AILVSPDAGGAKRVASL 190
+ITMDLHASQIQGFF IPVDNLYAEP++LKYI K I N +++VSPDAGGAKRV S+
Sbjct: 123 IITMDLHASQIQGFFDIPVDNLYAEPAILKYI--KESIPNWQTSVIVSPDAGGAKRVTSI 180
Query: 191 ADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHGA 250
AD+L+++FALIHKE ++ANEV +M LVG V GK +L+DDMADTCGT+ A+D L+E GA
Sbjct: 181 ADRLNVDFALIHKESKRANEVEKMTLVGSVEGKVAILVDDMADTCGTICMAADKLVEAGA 240
Query: 251 KEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDV---NILDQIDISPTLAEAIR 307
+V A HGIFSG A +L SK +V TNT+P D ++ + + IDIS LAEAIR
Sbjct: 241 DKVYAFCVHGIFSGPALTRLNASKFEAVVVTNTIPQDENMKKCSKIQCIDISMILAEAIR 300
Query: 308 RLHNGESVSYLFTHAAI 324
R HNGESVSYLF+H I
Sbjct: 301 RTHNGESVSYLFSHVPI 317
>SPBC3D6.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 341
Score = 273 bits (698), Expect = 2e-73
Identities = 153/329 (46%), Positives = 213/329 (64%), Gaps = 29/329 (8%)
Query: 19 SHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGEQEINDFLM 78
SHP+L ++I L L + + + ++SN ETSV I +S+R DVYI+ +G+ +ND LM
Sbjct: 11 SHPKLTESICEHLCLDIGRVELSKFSNGETSVRIKQSVRGCDVYIVSPASGQ--VNDHLM 68
Query: 79 ELLIIIHACRTASARRITAVIPNFPYARQ--DKKDKSRAPIT------------------ 118
ELLI+I AC+TASA+++TAV+P FPY+RQ K S AP++
Sbjct: 69 ELLIMISACKTASAKKVTAVLPVFPYSRQPDQKFSFSGAPLSDLQDAVVPCKKQTGYHPW 128
Query: 119 ----AKLVAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQ-HKTDIGN 173
LVA +L +G DH+ITMDLH Q QGFF IPVDNL+ P + YI + + N
Sbjct: 129 IAQSGTLVADLLMCSGADHIITMDLHDPQFQGFFDIPVDNLFGRPLLKHYISLNIPNYHN 188
Query: 174 AILVSPDAGGAKRVASLADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMAD 233
A++VSPDAGGAKR ++AD L L+FALIHK R+ S M LVGDV K +LIDD+ D
Sbjct: 189 AVIVSPDAGGAKRATAIADALGLDFALIHKNRRHEYGTSLM-LVGDVQNKVAILIDDLID 247
Query: 234 TCGTLVKASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVN-I 292
T TLV+A++ + EHGA ++ A+VTH + SG A +++K S + +++ TNT P + +
Sbjct: 248 TAYTLVRAAEFVKEHGASKIYALVTHCVLSGDAIERVKLSCIDKLIVTNTAPQTITPSGC 307
Query: 293 LDQIDISPTLAEAIRRLHNGESVSYLFTH 321
D ID++PT AEAIRR+HNGES+S L+ H
Sbjct: 308 FDIIDVAPTFAEAIRRIHNGESISILYDH 336
>Hs4506133 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 369
Score = 247 bits (631), Expect = 1e-65
Identities = 142/362 (39%), Positives = 215/362 (59%), Gaps = 41/362 (11%)
Query: 1 METSKRMSTNSIKLLAGNSHP---ELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIR 57
+ET ++ + L + NS+ EL++ IA LG+ + + VYQ N+ET V I ES+R
Sbjct: 9 LETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVR 68
Query: 58 DEDVYIIQTGTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPI 117
+DV+IIQT + +++N +MELLI+++AC+T+ A+ I VIP FPY++Q K K R I
Sbjct: 69 GKDVFIIQTVS--KDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRK-RGSI 125
Query: 118 TAKLVAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAIL 176
+KL+A M+ AG H+ITMDLH +IQGFF+IPVDNL A P +L+YIQ + D NA++
Sbjct: 126 VSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVI 185
Query: 177 VSPDAGGAKRVASLADKLDLNFALIHKERQKA---------------------------- 208
V+ AKR S A++L L A+IH E Q A
Sbjct: 186 VAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPM 245
Query: 209 ---NEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHGAKEVLAIVTHGIFSGS 265
E + +VGDV G+ +++DD+ D + + A++TL E GA ++ + THG+ S
Sbjct: 246 LIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSD 305
Query: 266 AEQKLKNSKLSRIVCTNTVPVD---LDVNILDQIDISPTLAEAIRRLHNGESVSYLFTHA 322
A ++++ S + +V TNT+P + L + +DIS L+EAIRR+HNGES+SYLF +
Sbjct: 306 APRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNI 365
Query: 323 AI 324
+
Sbjct: 366 GL 367
>At2g35390 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 352
Score = 240 bits (613), Expect = 2e-63
Identities = 134/324 (41%), Positives = 196/324 (60%), Gaps = 8/324 (2%)
Query: 1 METSKRMSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDED 60
ME S + +KL +G ++P LAQ IA +GL L + + ++++ E V + ES+R D
Sbjct: 31 MEKSVNRTNTRLKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCD 90
Query: 61 VYIIQTGTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAK 120
VY++Q N+ LMELLI++ ACR ASA+++TAVIP F YAR D+K + R I AK
Sbjct: 91 VYLVQPTC--TPTNENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAK 148
Query: 121 LVAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKT-DIGNAILVSP 179
LVA ++ AG D V+ DLH+ Q G+F IPVD++Y +P +L Y+ K+ + ++VSP
Sbjct: 149 LVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPSEDLVVVSP 208
Query: 180 DAGGAKRVASLADKL-DLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTL 238
D GG R + A KL D A++ K R N M L+GDV GK +++DDM DT GT+
Sbjct: 209 DVGGVARARAFAKKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTI 268
Query: 239 VKASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVNILDQ--- 295
VK + L + GA+EV A TH +FS A ++L L ++ TNT+PV + N Q
Sbjct: 269 VKGAALLHQEGAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPV-AEKNYFPQLTI 327
Query: 296 IDISPTLAEAIRRLHNGESVSYLF 319
+ ++ L E I R+H+ SVS +F
Sbjct: 328 LSVANLLGETIWRVHDDSSVSSIF 351
>At1g32380 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 400
Score = 237 bits (605), Expect = 2e-62
Identities = 131/324 (40%), Positives = 197/324 (60%), Gaps = 8/324 (2%)
Query: 1 METSKRMSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDED 60
+E S + +KL +G ++P L+Q IA +GL L + + ++++ E V + ES+R D
Sbjct: 79 LEKSVSRNNTKLKLFSGTANPALSQEIAWYMGLELGKVSIKRFADGEIYVQLKESVRGCD 138
Query: 61 VYIIQTGTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAK 120
V+++Q N+ LMELLI++ ACR ASA+++TAVIP F YAR D+K + R I AK
Sbjct: 139 VFLVQPTC--TPTNENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAK 196
Query: 121 LVAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKT-DIGNAILVSP 179
LVA ++ AG D V+ DLH+ Q G+F IPVD++Y +P +L Y+ K+ + ++VSP
Sbjct: 197 LVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSISSEDLVVVSP 256
Query: 180 DAGGAKRVASLADKL-DLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTL 238
D GG R + A KL D A++ K R N M L+GDV GK +++DD+ DT GT+
Sbjct: 257 DVGGVARARAFAKKLSDAPLAIVDKRRHGHNVAEVMNLIGDVKGKVAVMVDDIIDTAGTI 316
Query: 239 VKASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVNILDQ--- 295
VK + L E GA+EV A TH +FS A ++L + L ++ TNT+PV + N Q
Sbjct: 317 VKGAALLHEEGAREVYACCTHAVFSPPAIERLSSGLLQEVIVTNTLPV-AEKNYFPQLTI 375
Query: 296 IDISPTLAEAIRRLHNGESVSYLF 319
+ ++ L E I R+H+ SVS +F
Sbjct: 376 LSVANLLGETIWRVHDDSSVSSIF 399
>Hs4506131 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 356
Score = 228 bits (581), Expect = 9e-60
Identities = 137/337 (40%), Positives = 192/337 (56%), Gaps = 37/337 (10%)
Query: 22 ELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGEQEINDFLMELL 81
ELA+ I LG L VYQ +N ET V I E +R +D++IIQT +++N +MELL
Sbjct: 21 ELAKRITERLGAELGKSVVYQETNGETRVEIKEFVRGQDIFIIQTIP--RDVNTAVMELL 78
Query: 82 IIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAGCDHVITMDLHA 141
I+ +A +TA AR I VIP FPY++Q K K R I KL+A ML AG H+ITMDLH
Sbjct: 79 IMAYALKTACARNIIGVIPYFPYSKQSKMRK-RGSIVCKLLASMLAKAGLTHIITMDLHQ 137
Query: 142 SQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAILVSPDAGGAKRVASLADKLDLNFAL 200
+IQGFF PVDNL A P +L+YIQ + + NA++V+ AKR S A++L L A+
Sbjct: 138 KEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAV 197
Query: 201 IHKERQ------------------------------KANEVSRMVLVGDVTGKSCLLIDD 230
IH E Q A E + +VGDV G+ +++DD
Sbjct: 198 IHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDD 257
Query: 231 MADTCGTLVKASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVD--- 287
+ D + V A++ L E GA ++ + THGI S A + ++ S + +V TNTVP +
Sbjct: 258 IIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQK 317
Query: 288 LDVNILDQIDISPTLAEAIRRLHNGESVSYLFTHAAI 324
L + +DIS L+EAIRR+HNGES++YLF + +
Sbjct: 318 LQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITV 354
>At2g44530 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 386
Score = 226 bits (575), Expect = 5e-59
Identities = 128/321 (39%), Positives = 191/321 (58%), Gaps = 8/321 (2%)
Query: 1 METSKRMSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDED 60
+E S +T +++ +G ++P LAQ I+ LGL L I + ++++ E V + ES+R D
Sbjct: 67 LEDSIYQNTTRLRIFSGTANPILAQEISCYLGLDLGKIKIKRFADGEIYVQLQESVRGCD 126
Query: 61 VYIIQTGTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAK 120
V+++Q N+ LMELL++I ACR ASA+ ITAVIP F YAR D+K + R I AK
Sbjct: 127 VFLVQPTC--PPANENLMELLVMIDACRRASAKTITAVIPYFGYARADRKTQGRESIAAK 184
Query: 121 LVAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKT-DIGNAILVSP 179
LVA ++ +G D V+ DLH+ Q G+F IPVD++Y +P +L Y+ K + ++VSP
Sbjct: 185 LVANLITQSGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKAISSEDLVVVSP 244
Query: 180 DAGGAKRVASLADKL-DLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTL 238
D GG R + A KL D A++ K R N M L+GDV GK +++DDM DT GT+
Sbjct: 245 DVGGVARARAFAKKLSDAPLAIVDKRRHGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTI 304
Query: 239 VKASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIVCTNTVPVDLDVNILDQ--- 295
K + L + GA+EV A TH +FS A +L + ++ TNT+P+ + N Q
Sbjct: 305 SKGAALLHQEGAREVYACTTHAVFSPPAISRLSSGLFQEVIITNTIPLS-EKNYFPQLTV 363
Query: 296 IDISPTLAEAIRRLHNGESVS 316
+ ++ L E I R+H+ SVS
Sbjct: 364 LSVANLLGETIWRVHDDCSVS 384
>CE03789 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 353
Score = 216 bits (550), Expect = 4e-56
Identities = 122/343 (35%), Positives = 203/343 (58%), Gaps = 34/343 (9%)
Query: 8 STNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTG 67
+++ + LL GNSHPELA+ ++ L +RL VY +N+ETSV I +S+R + V+I+Q+G
Sbjct: 7 ASSGMVLLTGNSHPELAKMVSERLEIRLGEATVYNKTNRETSVDIKQSVRGKHVFILQSG 66
Query: 68 TGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLE 127
+ + +N+ +MELL++I+AC+T+ ++ IT ++P PY++Q + + R+ I KLVA+M+
Sbjct: 67 S--KNVNNDVMELLVLIYACKTSMSKTITVIMPYLPYSKQCRMLR-RSSIAMKLVAEMIC 123
Query: 128 TAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKT-DIGNAILVSPDAGGAKR 186
AG ++++DL+ +IQGFF PVDNL A P L++I+ D NAI+V+ G +
Sbjct: 124 KAGASRLVSLDLYKKEIQGFFSCPVDNLRASPFFLQHIKTNIPDYKNAIIVAKSPGVMNK 183
Query: 187 VASLADKLDLNFALIHKER---------------------------QKANEVSRMVLVGD 219
S AD+L L A+IH E+ Q++ + + +VGD
Sbjct: 184 ATSYADRLRLGVAVIHGEQKDEEESGLEDGRQSPPPNVTSYDFLPAQESKQKPPLTVVGD 243
Query: 220 VTGKSCLLIDDMADTCGTLVKASDTLLEHGAKEVLAIVTHGIFSGSAEQKLKNSKLSRIV 279
V G+ +++DD+ D + V A++ L GA ++ I THG+ S A L+ S ++ ++
Sbjct: 244 VGGRIAIMVDDIIDDAQSFVAAAEVLKARGAYKIYVIATHGVLSSDAPALLEASPITEVI 303
Query: 280 CTNTVPVDLD---VNILDQIDISPTLAEAIRRLHNGESVSYLF 319
TNTVP DL + + +D+S + EAIRR+ + ES+ LF
Sbjct: 304 VTNTVPHDLQKMRCHKIKTVDVSLMICEAIRRIFHNESMGQLF 346
>SPAC4A8.14 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 409
Score = 208 bits (529), Expect = 1e-53
Identities = 107/204 (52%), Positives = 151/204 (73%), Gaps = 3/204 (1%)
Query: 11 SIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGE 70
S ++ G SHPEL I+ LG+ ++ + +++N ETSV I ES+RD+DV+I+Q+G+
Sbjct: 3 SATIIGGGSHPELLHLISNRLGITPCDVSLKRFANGETSVEIRESVRDKDVFILQSGSST 62
Query: 71 QEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAG 130
+ND LMELLIII AC+ SA+RITAV+P FPY++Q K K R ITA++VA +L AG
Sbjct: 63 --VNDSLMELLIIISACKGGSAKRITAVMPYFPYSKQSKMRKYRDAITARMVANLLTVAG 120
Query: 131 CDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKT-DIGNAILVSPDAGGAKRVAS 189
DH+IT+DLHASQ+QGFF PVDNLYAEP++ ++I+ D A++VS + GGAKRV S
Sbjct: 121 VDHIITLDLHASQMQGFFTRPVDNLYAEPNIAEWIRRNVDDWEEAVVVSKNPGGAKRVTS 180
Query: 190 LADKLDLNFALIHKERQKANEVSR 213
LAD L+L+FALI+ +RQ+++ S+
Sbjct: 181 LADTLNLDFALINTDRQRSSHFSQ 204
Score = 89.7 bits (221), Expect = 5e-18
Identities = 54/115 (46%), Positives = 73/115 (62%), Gaps = 6/115 (5%)
Query: 214 MVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEH-GAKEVLAIVTHGIFSGSAEQKLKN 272
+ LVGDV GK+ LLIDD + + AS+ L++ GAK V+ I THGIF + L++
Sbjct: 294 ITLVGDVNGKTALLIDDTIENPTAFIVASEHLVKRCGAKRVIVIGTHGIFQNKCLKDLQS 353
Query: 273 SK-LSRIVCTNTVPVD----LDVNILDQIDISPTLAEAIRRLHNGESVSYLFTHA 322
+ + +IV TNT P+ L+ + L IDIS LAEAIRR HNGES+S+LF A
Sbjct: 354 CEYIEQIVVTNTYPIKPQAVLECDKLTVIDISGVLAEAIRRTHNGESISFLFKKA 408
>YKL181w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 427
Score = 207 bits (528), Expect = 1e-53
Identities = 103/200 (51%), Positives = 146/200 (72%), Gaps = 3/200 (1%)
Query: 13 KLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGEQE 72
K+ GNSHPEL + + LG+ + + +++N ETSV IG S+RDEDVY+IQ+G+
Sbjct: 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS--PS 62
Query: 73 INDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAGCD 132
IND +MELLI++ ACR SAR+ITAVIP FPY++Q K + R ITA+++A +L AG D
Sbjct: 63 INDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGAD 122
Query: 133 HVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHKT-DIGNAILVSPDAGGAKRVASLA 191
HV++MDLHASQ+QGFF PVDNLY PS+ K+I+ D +A++VS + GG KRV +LA
Sbjct: 123 HVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTALA 182
Query: 192 DKLDLNFALIHKERQKANEV 211
D L +NFA+IH +R+++ ++
Sbjct: 183 DSLKINFAMIHTDRRRSKDL 202
Score = 86.3 bits (212), Expect = 6e-17
Identities = 49/116 (42%), Positives = 73/116 (62%), Gaps = 6/116 (5%)
Query: 214 MVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEH-GAKEVLAIVTHGIFSGSAEQKL-K 271
+ LVG+V G+S +++DDM D G+ + A++ L+++ GAK+V + THGIF+G ++L K
Sbjct: 310 ITLVGNVRGRSAIILDDMIDRPGSFISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEK 369
Query: 272 NSKLSRIVCTNTVPVDLD----VNILDQIDISPTLAEAIRRLHNGESVSYLFTHAA 323
+ + IV TNT P+ + L ID+SP AE IRR H GES+S LF A
Sbjct: 370 SDAIDTIVVTNTYPISGERIAGSKKLVTIDVSPIFAECIRRDHYGESISVLFDSLA 425
>7301964 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 386
Score = 192 bits (489), Expect = 4e-49
Identities = 136/384 (35%), Positives = 203/384 (52%), Gaps = 71/384 (18%)
Query: 8 STNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTG 67
ST+ I ++ GNSHP+LA +A +G++ V+ SN+ET V I +S+R +D+YIIQTG
Sbjct: 5 STSDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTG 64
Query: 68 TGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLE 127
T ++ N+ +MELLI+ +AC+T+SAR I VIP PY++Q K K R I +KL+A+M+
Sbjct: 65 T--KDANNNIMELLIMAYACKTSSARSIVGVIPYLPYSKQCKMRK-RGCIVSKLLAKMMC 121
Query: 128 TAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAILVSPDAGGAKR 186
T+G H+ITMDLH +IQGFF IPVDNL A P +L+YIQ D N+++V+ + G AK+
Sbjct: 122 TSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKK 181
Query: 187 VASLADKLDLNFALIHKERQK--ANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDT 244
S A++L L A+IH E+++ A+EV + S LL + + C + T
Sbjct: 182 ANSYAERLRLGLAVIHGEQKETDADEVDGRYSPPPTSAYSNLL-GNSVEMCLPATPRNST 240
Query: 245 -------------------LLEHGAKEVLAIVTHGIFSG-----------------SAEQ 268
+ EH K + G SG +A +
Sbjct: 241 PQHAPTSSARQRTTSVSVGVPEHIVKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAE 300
Query: 269 KLKNSKLSRI-------VCTNTVPVDLDVNILDQ---------------------IDISP 300
LK + +I + ++ P LD + +D+ IDIS
Sbjct: 301 MLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQKLQCHKIKTIDISI 360
Query: 301 TLAEAIRRLHNGESVSYLFTHAAI 324
+AEAIRR+HN ES+SYLF + +
Sbjct: 361 LIAEAIRRIHNKESMSYLFRNVTL 384
>YOL061w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 496
Score = 135 bits (340), Expect = 8e-32
Identities = 94/270 (34%), Positives = 130/270 (47%), Gaps = 69/270 (25%)
Query: 121 LVAQMLETAGCDHVITMDLHASQIQGFFHIPVDNLYAEPSVLKYIQHK-TDIGNAILVSP 179
L+A +L AG DHVITMDLH Q GFF IPVDNLY +P YIQH+ D +A++VSP
Sbjct: 225 LIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVSP 284
Query: 180 DAGGAKRVASLADKLDLNFALIHKERQK---------------ANEVSRMVLV------- 217
DAGGAKR ++AD L+L+FALIHKER+ + VS LV
Sbjct: 285 DAGGAKRATAIADALELSFALIHKERRSQLLKGPPDATLTSGGSLPVSPRPLVTTLVSSQ 344
Query: 218 ----GDVTGKSCLLIDDMADTCGTLVKASD-------TLLEHGAKEVLAIVTHGIFSGS- 265
TG + L + T T ++S+ T+L + + I+ + S
Sbjct: 345 NTTSSGATGVAALEMKKTTSTSSTSSQSSNSSKFVQTTMLVGDVRNKVCIIVDDLVDTSY 404
Query: 266 -----------------------------AEQKLKNSKLSRIVCTNTVPVDLDVNIL--- 293
A +++ S + +++ +NTVP D + L
Sbjct: 405 TITRAAKLLKDQGSTKVYALITHGVFSGDALERIGQSSIDKLIISNTVPQDRTLQYLGKD 464
Query: 294 --DQIDISPTLAEAIRRLHNGESVSYLFTH 321
D ID+S + EAIRR+HNGES+S LF H
Sbjct: 465 RVDVIDVSCIIGEAIRRIHNGESISMLFEH 494
Score = 97.1 bits (240), Expect = 3e-20
Identities = 51/114 (44%), Positives = 76/114 (65%), Gaps = 7/114 (6%)
Query: 7 MSTNSIKLLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQT 66
MS ++I + G+SHPEL I L + S + + ++SN ET++ + ES+R++DVYIIQ+
Sbjct: 1 MSMSNIVVFGGDSHPELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYIIQS 60
Query: 67 GTGEQEINDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAK 120
G G ++ND M+LLI+I AC++ASA R+TAV+P Y+RQ P TAK
Sbjct: 61 GCG--QVNDTFMQLLILISACKSASASRVTAVMPYLCYSRQPD-----IPYTAK 107
>Hs20542182 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 271
Score = 77.0 bits (188), Expect = 3e-14
Identities = 47/142 (33%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 14 LLAGNSHPELAQNIARTLGLRLSNIGVYQYSNQETSVTIGESIRDEDVYIIQTGTGEQEI 73
+L G+S LAQ + + GL L + ++SNQE S+ GE +RD+ Y+I +I
Sbjct: 46 VLLGSSSLGLAQKVVKRWGLELGKVVTKKFSNQEVSIVSGERMRDQAAYVI------VKI 99
Query: 74 NDFLMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLETAGCDH 133
ND L L + + C+ + + AV+ PYA+QD+KDKS ++AKLVA + AG
Sbjct: 100 NDTLTS-LAMTNVCKATWSSGMKAVLSCSPYAQQDQKDKSHPAVSAKLVANVFSVAGRSV 158
Query: 134 VITMDLHASQIQGFFHIPVDNL 155
+ I+ + + VD++
Sbjct: 159 GVDRMFLVGDIKDWVAVLVDDI 180
>At1g10700 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 411
Score = 71.6 bits (174), Expect = 1e-12
Identities = 53/202 (26%), Positives = 90/202 (44%), Gaps = 10/202 (4%)
Query: 77 LMELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLET-----AGC 131
+ E L +I+A T V+P FP ++ + TA +A++L G
Sbjct: 165 IFEQLSVIYALPKLFVSSFTLVLPFFPTGTSERMEDEGDVATAFTLARILSNIPTSRGGP 224
Query: 132 DHVITMDLHASQIQGFFHIPVDNLYAE--PSVLKYIQHKTDIGNAILVSPDAGGAKRVAS 189
++T D+HA Q + +F + + P + +Q D N + PD G KR
Sbjct: 225 TSLVTFDIHALQERFYFGDTILPCFESGIPLLKSRLQSLPDSDNISIAFPDDGAWKRFHK 284
Query: 190 LADKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHG 249
+ +K R + R + GD G+ +++DD+ + GTL++ L HG
Sbjct: 285 QLQHYPT--IVCNKVRMGDKRIVR-IKEGDAEGRHVVIVDDLVQSGGTLIECQKVLAAHG 341
Query: 250 AKEVLAIVTHGIFSGSAEQKLK 271
A ++ A VTHGIF S+ ++ K
Sbjct: 342 AAKISAYVTHGIFPRSSWKRFK 363
>At2g42910 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 337
Score = 69.3 bits (168), Expect = 7e-12
Identities = 66/263 (25%), Positives = 118/263 (44%), Gaps = 17/263 (6%)
Query: 22 ELAQNIARTLG-LRLSNIGVYQYSNQETSVTIGES--IRDEDVYIIQTGTGEQEINDFLM 78
ELA+NIA + L +I +++ ++ I + IR + V + + + I
Sbjct: 38 ELARNIAAESDHITLQSINWRSFADGFPNLFINNAHDIRGQHVAFLASFSSPAVI----F 93
Query: 79 ELLIIIHACRTASARRITAVIPNFPYARQDKKDKSRAPITAKLVAQMLET-----AGCDH 133
E + +I+ T V+P FP ++ ++ TA +A+++ G
Sbjct: 94 EQISVIYLLPRLFVASFTLVLPFFPTGSFERMEEEGDVATAFTMARIVSNIPISRGGPTS 153
Query: 134 VITMDLHASQIQGFFHIPVDNLYAE--PSVLKYIQHKTDIGNAILVSPDAGGAKRVASLA 191
V+ D+HA Q + +F V L+ P + K +Q + I+ PD G KR L
Sbjct: 154 VVIYDIHALQERFYFADQVLPLFETGIPLLTKRLQQLPETEKVIVAFPDDGAWKRFHKLL 213
Query: 192 DKLDLNFALIHKERQKANEVSRMVLVGDVTGKSCLLIDDMADTCGTLVKASDTLLEHGAK 251
D + K R+ + R+ G+ G +++DD+ + GTL++ L HGA
Sbjct: 214 DHYPT--VVCTKVREGDKRIVRLK-EGNPAGCHVVIVDDLVQSGGTLIECQKVLAAHGAV 270
Query: 252 EVLAIVTHGIFSGSAEQKLKNSK 274
+V A VTHG+F S+ ++ + K
Sbjct: 271 KVSAYVTHGVFPKSSWERFTHKK 293
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.133 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,262,478
Number of Sequences: 60738
Number of extensions: 666635
Number of successful extensions: 1724
Number of sequences better than 1.0e-05: 26
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1615
Number of HSP's gapped (non-prelim): 34
length of query: 324
length of database: 30,389,216
effective HSP length: 106
effective length of query: 218
effective length of database: 23,950,988
effective search space: 5221315384
effective search space used: 5221315384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)