ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5474 good S KOG0269 Function unknown WD40 repeat-containing protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5474 1872227 1876189 1321
(1321 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL138c [S] KOG0269 WD40 repeat-containing protein 815 0.0
SPAC4F8.11 [S] KOG0269 WD40 repeat-containing protein 112 3e-24
7301821 [S] KOG0269 WD40 repeat-containing protein 96 4e-19
Hs14149987 [S] KOG0269 WD40 repeat-containing protein 92 4e-18
SPAC29A4.18 [B] KOG0264 Nucleosome remodeling factor subunit CAF... 59 7e-08
ECU07g0750 [B] KOG0264 Nucleosome remodeling factor subunit CAF1... 59 7e-08
YDL195w [U] KOG0307 Vesicle coat complex COPII subunit SEC31 56 4e-07
Hs5031817 [D] KOG0267 Microtubule severing protein katanin p80 s... 55 7e-07
Hs14149696 [U] KOG0307 Vesicle coat complex COPII subunit SEC31 55 7e-07
YBR195c [B] KOG0264 Nucleosome remodeling factor subunit CAF1/NU... 54 2e-06
Hs7705258 [U] KOG0307 Vesicle coat complex COPII subunit SEC31 53 4e-06
CE28516 [S] KOG0269 WD40 repeat-containing protein 53 4e-06
Hs7662370 [U] KOG0307 Vesicle coat complex COPII subunit SEC31 52 5e-06
CE27713 [A] KOG0265 U5 snRNP-specific protein-like factor and re... 52 5e-06
CE24997 [S] KOG0290 Conserved WD40 repeat-containing protein AN11 52 8e-06
>YOL138c [S] KOG0269 WD40 repeat-containing protein
Length = 1341
Score = 815 bits (2105), Expect = 0.0
Identities = 507/1336 (37%), Positives = 729/1336 (53%), Gaps = 138/1336 (10%)
Query: 45 TSPFRISPKYKPDSRTPFSFDGTGNVGPESSLNEEESNARWRPSESSFDKR-RTFHGAKY 103
TS F S Y P + P++ TG++ +SN + + +++ + R G Y
Sbjct: 84 TSSFNDS--YLPYDKNPYA-KTTGSMS-------NKSNMKIKTKKNAINTNTRKSSGLIY 133
Query: 104 SLSIGKEVSSIDKINSPESRSLIIAGKSHLGIYTFDEDSKTITNVHDFLQTAKTNTGITK 163
+ + KE+SSIDK+N P L+ AGK+HLG+Y F ++I VHDF+ T +NT T+
Sbjct: 134 TTKVDKELSSIDKVNDPNINGLVCAGKTHLGLYKFSPSDRSIKCVHDFI-TPNSNTS-TR 191
Query: 164 NTSSTLRRTTK-----KISTISDVKAGFYNHKNYVAICGTSTSVAIYDINKTSAIDNPVV 218
T+S L + +K K STI+DVK GF N+KN +A+C ST+++IYD+NK+S+IDNP++
Sbjct: 192 GTTSLLPKLSKRTRQNKFSTIADVKTGFNNYKNCIAVCNNSTAISIYDLNKSSSIDNPLI 251
Query: 219 TSLSEHTRSINSVDFNMVQTSLLISGGQDGCIKIWDLRSPKI-STTRSDVSINTGSDSIR 277
TSL EHTRSINS DFNMV+++L+ISGGQD C+KIWDLRS K S+ RSD+SINT SDSIR
Sbjct: 252 TSLCEHTRSINSFDFNMVESNLIISGGQDSCVKIWDLRSNKSKSSNRSDISINTASDSIR 311
Query: 278 DVKWMPSYEFSN------DTNGLSNRHFKFASVHDSGLLLKFDLRQPNQAEKKINAHSGP 331
DVKWMP Y F++ T G +KFAS+HDSG LLKFDLRQP Q EKK+NAH+GP
Sbjct: 312 DVKWMPGYNFASKNDQGSSTYGNLKSGYKFASIHDSGYLLKFDLRQPAQYEKKLNAHTGP 371
Query: 332 ALCLNWHPHQDYIISGGRDGKCCLWYVGDKSNQVGNISSTNLNSSN-PATHNLSSSYPLG 390
LCLNWHP+Q+YI +GGRDGK CLW+VGD +N N T LN N P+ H ++S L
Sbjct: 372 GLCLNWHPNQEYIATGGRDGKSCLWFVGDNANAAEN---TVLNYGNSPSLHAPNTS--LN 426
Query: 391 LSNTLAFPELTINTARSMNKLKFRPKYETNVFNSLIGTSSMGEDSDVSVYSLARKYIPKN 450
S +LAFP+LTINT + KLKF+P Y +N++NSL+G SSMG++++V +YSLARKYIPK+
Sbjct: 427 NSGSLAFPKLTINTGYPVTKLKFKPAYSSNIYNSLLGISSMGDEAEVRIYSLARKYIPKH 486
Query: 451 VIASSAPSVGFVWWDDDTIFNIDKQNTVTGWDISHEPTVLDNLPKNTIKWRDLDGDGILF 510
V+ S PS+G VWWD++ IFNIDK + GWDI+ EPTVL+NL KNT WRDLDG+G+L
Sbjct: 487 VLLSETPSLGLVWWDENLIFNIDKGTRINGWDINKEPTVLENLSKNTTTWRDLDGNGLLS 546
Query: 511 LDQKPGGYLSQEETVLTPGSGENRKMPFTHRMSSATANSFXXXXXXXXXXXXXXXXXXXX 570
+ Q+ G Y E + S +K P T + N
Sbjct: 547 VGQEIGSYEVVEPELQPTSSTTCKKHPGTIKNPK---NGNPENQGIIGGIKKGFSHTGLT 603
Query: 571 XXXXLGMSQLHQGNVLGERS-TMSKHAQSVNSKFSPSVNSSPWTNPYSSPHHNSIVSGSE 629
L G +S T++ A S NS + + +P T + E
Sbjct: 604 SFTPERPPTLKAGPTFSTKSLTLASGASSFNSSSASLTSLTPQTE-----------NREE 652
Query: 630 SALHAVNDSFLQSPYLIGLDFPHILNTIRNTRLAEFNRKVESAALLELKSSPTEVFKFLA 689
A ++ P +I LD P I N IR T++A +K + +K+SP E FK+LA
Sbjct: 653 IA--------IEPPCIITLDIPQIFNNIRLTKIAHSRKKNVISESSSMKNSPVEKFKYLA 704
Query: 690 RELKFSY--KYNSIETKDNGRELD---------SSSTHGSVDSKTN-------------- 724
R+LKFSY ++N ++ D + D ++ THG + TN
Sbjct: 705 RQLKFSYIREHNVSDSADTAYKNDIENIDVVKNATETHGDNTTTTNNNDDGDDDDDDDDD 764
Query: 725 -------LMEKLGLSENNTWTHLI------KYTKSHDSDEVISKGTELKTPVSDKSANIE 771
L++K ENNTW L+ K +K + S ++++ +S SA
Sbjct: 765 DKIIESHLLKKYNFPENNTWATLMNEKVNNKKSKRNSSSSREFDEKDVRSSISSISA--- 821
Query: 772 KSATNHKAETNQDENSSCINSSNQVKTKNLIELITLCDKNAEIYIMLEDFSNYKIWLLMR 831
S +H D+N + + Q K + L++LI++ NA +Y+ ++D +N+KIW+L+R
Sbjct: 822 -SRQSHDRARKIDKN---VEAELQEKIQTLVDLISIATHNASVYLSIDDLTNFKIWILIR 877
Query: 832 DSLLWDLKVLTES-MAVDVTADQEVNDQSSIDQPWKKNDSFTSLKEARQXXXXXXXXXXX 890
DSLLWDLK +T S ++ D ++ + N+ S ++ +LK ++
Sbjct: 878 DSLLWDLKWMTSSQISSDNASNMDANESSDF-------EAGENLKTGKEFPEEDGAGTSG 930
Query: 891 XXXXXXXVNTNNRHSFNEPTHLTQTPPVSHLKAQLQGSKETTTISRADSIQNSLQNDIIE 950
R + +EP+ + PVS LK QL K T I A ++S +
Sbjct: 931 AESLVEERPQAFRANSDEPSD-AEKKPVSKLKEQL---KNTEIIPYAQPNEDSDE----V 982
Query: 951 IRKLRQSHGDRAELAIDXXXXXXXXXXLTKRAFEEDENNKQFINIPRRESGPSALMPSPS 1010
+ KL++ R E + EEDE+ Q P SA +
Sbjct: 983 LTKLKELQNQRLESRTKMGETVSDDVII-----EEDEHEHQEEEQPHDSPTKSAQFHASP 1037
Query: 1011 HVSSQSEIPSNPENHHQPRRPRTSFIDSFMSQLRSPGSSNVDAD-REXXXXXXXXXXXXX 1069
S IP + H R SFID+FM L SP N D D
Sbjct: 1038 IAKS---IPILQKREH-----RKSFIDTFM--LHSPNGYNGDTDIGNEDDNISPRFTYNS 1087
Query: 1070 XXXXXXLNSKKSQNANHNKLKSATEVSDILESEFATQK---SWNGSVAKTTTQMSGITAL 1126
++S +S ++L++ ++S + + S S+ + S +T
Sbjct: 1088 VSPRSKVSSLQSYATTTSQLETFKKLSSHTAPIIGSPRHAPSRPDSIGREQLS-SSLTKK 1146
Query: 1127 MNETKKLENTITPPWSSRRLIHQLYEQSVASGNILLTMAILLLFQDMFQLVDTETVKNSI 1186
+ + KK+ PPW +++LI QLY Q+ +GN++LT+ IL LFQ ++Q+ + + K++I
Sbjct: 1147 LAKCKKI--IADPPWDTKKLIKQLYNQATETGNVVLTVNILFLFQTIYQITEIDIAKDAI 1204
Query: 1187 AEFTELLHRYELFEIAAELMKNCPYEDIXXXXXXXXXIQLFCDKCNKPLVNESSKEKIIK 1246
A F LLHRYELF IAA+++K CP+EDI I+LFC++C + + NESSKEK+
Sbjct: 1205 AHFLLLLHRYELFGIAADVLKYCPFEDIMGSEGDQSSIRLFCERCGELITNESSKEKLRA 1264
Query: 1247 ERLE-GNSSAMSRFGYWYCDSCSKRNTLCCFCNKPMKSLAISMLNCGHEGHFECLKKWFF 1305
E + GN M +FGYWYCDSC K+NT C C +P+K L + +L CGHEGHF+C+++WF
Sbjct: 1265 EAQQTGNKKIMDKFGYWYCDSCKKKNTSCVLCERPLKKLTMVILPCGHEGHFQCIQEWFL 1324
Query: 1306 DENMDVCPLGCPAILF 1321
DEN CP GCP + F
Sbjct: 1325 DENEQECPGGCPGVAF 1340
>SPAC4F8.11 [S] KOG0269 WD40 repeat-containing protein
Length = 846
Score = 112 bits (281), Expect = 3e-24
Identities = 94/392 (23%), Positives = 179/392 (44%), Gaps = 74/392 (18%)
Query: 112 SSIDKINSPESRSLI-IAGKSHLGIYTFDEDS-KTITNVHDFLQTAKTNTGITKNTSSTL 169
+SI I+ +SR+ + +AG+ L + + +S K + D LQ K+T
Sbjct: 40 ASISAISVNKSRTKVGVAGRELLKVLAVNPNSSKPPVCISDLLQ---------KSTQ--- 87
Query: 170 RRTTKKISTISDVKAGFYNHKNYVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSIN 229
TK IS +DVK G N + C ++ ++D+N + ++ +EH+R+++
Sbjct: 88 ---TKHISC-NDVKWGSSFASNLIFTCSPLGNLNVWDVNLEA-----LLYDFNEHSRAVH 138
Query: 230 SVDFNMVQTSLLISGGQDGCIKIWDLRSPKISTTRSDVSINTGSDSIRDVKWMPSYEFSN 289
+D + S +++ QDG IK+WD + + S ++ S++ RDV + PS
Sbjct: 139 KLDISSFHPSYVLTASQDGLIKLWDYKE-----SSSTITFRGNSEAARDVVFSPS----- 188
Query: 290 DTNGLSNRHFKFASVHDSGLLLKFDLRQPNQAEKKINAHSGPALCLNWHPHQDYIISGGR 349
+ N +F + +DSG+L K+D+R P K+ AH+G LC+N+ P+ ++ S GR
Sbjct: 189 EPN-------EFVAAYDSGILQKWDIRFPKLPFLKLAAHNGVVLCVNYSPNGVFLASCGR 241
Query: 350 DGKCCLWYVGDKSNQVGNISSTNLNSSNPATHNLSSSYPLGLSNTLAFPELTINTARSMN 409
D +W +T N S +TIN +N
Sbjct: 242 DKTIRIW---------------------DSTSNKKKSL------------ITINNVSPLN 268
Query: 410 KLKFRPKYETNVFNSLIGTSSMGEDSDVSVYSLARKYIPKNVIASSAPSVGFVWW-DDDT 468
+++RP + + ++ + +SS+ D+ ++V+ + R YIP ++ V + W +
Sbjct: 269 CVRWRPANQQSRGSNQLASSSLVGDTAINVWDITRPYIPYRTVSCHDSIVSTMHWASTEL 328
Query: 469 IFNIDKQNTVTGWDISHEPTVLDNLPKNTIKW 500
+++ K + + + +D LP+ T W
Sbjct: 329 LWSCSKDGIFSQTRVENAFNCIDMLPRATSSW 360
>7301821 [S] KOG0269 WD40 repeat-containing protein
Length = 776
Score = 95.9 bits (237), Expect = 4e-19
Identities = 92/372 (24%), Positives = 168/372 (44%), Gaps = 71/372 (19%)
Query: 115 DKINSPESRSLIIAGKSHLGIYTFDEDSKTITNV-HDFLQTAKTNT-GITKNTSSTLRRT 172
D + + SL I + H ++D+ I L+ N+ G T+ S +R
Sbjct: 3 DSVEDTSTISLRICLEGHANALALNKDNNQIALAGRSLLKVYSINSNGFTE--SCNMRGK 60
Query: 173 TKKISTISDVKAGFYNHKNYVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSINSVD 232
+ +S ++ A N +A T+ V+++D++K +V +EH R+ ++V
Sbjct: 61 NQNLSYSANDVAWSTLDSNLLATAATNGVVSVWDLSKFGRQKQLLV--YNEHERTAHTVT 118
Query: 233 FNMVQTSLLISGGQDGCIKIWDLRSPKISTTRSDVSINT---GSDSIRDVKWMPSYEFSN 289
F+ + ++LISG QDG IK +D+RS K SINT S+S+RDVK FS
Sbjct: 119 FHSSEPNILISGSQDGTIKCFDIRSDK--------SINTYFCNSESVRDVK------FSP 164
Query: 290 DTNGLSNRHFKFASVHDSGLLLKFDLRQPNQAEKKINAHSGPALCLNWHPHQDYIISGGR 349
T + F++V ++G + +D+R+ ++ + AH GP +WHP ++++ +G R
Sbjct: 165 HTQNI------FSAVSENGTVQLWDMRKWDKCMVQFTAHYGPVYTCDWHPTRNWLATGSR 218
Query: 350 DGKCCLWYVGDKSNQVGNISSTNLNSSNPATHNLSSSYPLGLSNTLAFPELTINTARSMN 409
D + +W + + GL E TI+T +
Sbjct: 219 DKQIKVWNMDGRP---------------------------GL-------EHTIHTIAVVG 244
Query: 410 KLKFRPKYETNVFNSLIGTSSMGEDSDVSVYSLARKYIP-KNVIASSAPSVGFVWWDDDT 468
++K+RP+ + I + ++ D V V+ + R YIP + + + G W D+
Sbjct: 245 RVKWRPERTYH-----IASCALVVDYSVHVWDIRRPYIPFASFNEHTNVTTGIAWQGSDS 299
Query: 469 --IFNIDKQNTV 478
+ +I K +T+
Sbjct: 300 HCLLSISKDSTI 311
Score = 58.5 bits (140), Expect = 7e-08
Identities = 35/169 (20%), Positives = 65/169 (37%), Gaps = 24/169 (14%)
Query: 1139 PPWSSRRLIHQLYEQSVASGNILLTMAILLLFQDMFQL--VDTETVKNSIAEFTELLHRY 1196
P W + + G++ + +L+ + +L +D V++ + + LHRY
Sbjct: 613 PMWEPHKFVSDALMLMNDVGDVQTALTVLIALGEARKLLPIDDALVEHWFYTYVDQLHRY 672
Query: 1197 ELFEIAAELMKNCPYEDIXXXXXXXXXIQLFCDKCNKPLVNESSKEKIIKERLEGNSSAM 1256
EL+ A E++ + + C +C +P+ +
Sbjct: 673 ELWNEACEVINRSWLRSVQQLNQHSTAMHTNCGECGRPMGGKVG---------------- 716
Query: 1257 SRFGYWYCDSC-SKRNTLCCFCNKPMKSLAISMLNCGHEGHFECLKKWF 1304
WYCD C S ++ CC C ++ + C H GH E L+K+F
Sbjct: 717 -----WYCDKCKSMQSAKCCVCGLIVRGVYAWCQGCSHGGHIEHLQKYF 760
>Hs14149987 [S] KOG0269 WD40 repeat-containing protein
Length = 790
Score = 92.4 bits (228), Expect = 4e-18
Identities = 79/330 (23%), Positives = 148/330 (43%), Gaps = 79/330 (23%)
Query: 121 ESRSLIIAGKSHLGIYTFDEDSKTITNVHDFLQTAKTNTGITKNTSSTLRRTTKKISTIS 180
++ +++AG+S IY +E+ F++ K N + + S L + +
Sbjct: 37 DAAQVVVAGRSIFKIYAIEEEQ--------FVE--KLNLRVGRKPSLNL--------SCA 78
Query: 181 DVKAGFYNHKNYVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSINSVDFNMVQTSL 240
DV +N +A T+ V +++ + S N +EH R++N V F+ + +
Sbjct: 79 DV-VWHQMDENLLATAATNGVVVTWNLGRPSR--NKQDQLFTEHKRTVNKVCFHPTEAHV 135
Query: 241 LISGGQDGCIKIWDLRSPKISTTRSDVSINTG-SDSIRDVKWMPSYEFSNDTNGLSNRHF 299
L+SG QDG +K +DLR + VS +G S+S+RDV++ +F
Sbjct: 136 LLSGSQDGFMKCFDLRR------KDSVSTFSGQSESVRDVQFS------------IRDYF 177
Query: 300 KFASVHDSGLLLKFDLRQPNQAEKKINAHSGPALCLNWHPH-QDYIISGGRDGKCCLWYV 358
FAS ++G + +D+R+P++ E+ AH+GP C +WHP + ++ +GGRD +W
Sbjct: 178 TFASTFENGNVQLWDIRRPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVW-- 235
Query: 359 GDKSNQVGNISSTNLNSSNPATHNLSSSYPLGLSNTLAFPELTINTARSMNKLKFRPKYE 418
+ TH + + T S+ ++K+RP+
Sbjct: 236 ------------------DMTTHRAKEMH-------------CVQTIASVARVKWRPECR 264
Query: 419 TNVFNSLIGTSSMGEDSDVSVYSLARKYIP 448
+ + T SM D ++ V+ + R ++P
Sbjct: 265 HH-----LATCSMMVDHNIYVWDVRRPFVP 289
Score = 67.4 bits (163), Expect = 1e-10
Identities = 37/193 (19%), Positives = 81/193 (41%), Gaps = 25/193 (12%)
Query: 1125 ALMNETKKLENTITPPWSSRRLIHQLYEQSVASGNILLTMAILLLFQDMFQL-VDTETVK 1183
+L++ + L ++ PP L+ + G++ + +++L++ + + +D +T +
Sbjct: 615 SLLSVSHALYDSRLPPDFFGVLVRDMLHFYAEQGDVQMAVSVLIVLGERVRKDIDEQTQE 674
Query: 1184 NSIAEFTELLHRYELFEIAAELMKNCPYEDIXXXXXXXXXIQLFCDKCNKPLVNESSKEK 1243
+ + +LL R+ L+ ++ E++K + + + C C +P+ +
Sbjct: 675 HWYTSYIDLLQRFRLWNVSNEVVKLSTSRAVSCLNQASTTLHVNCSHCKRPMSSRG---- 730
Query: 1244 IIKERLEGNSSAMSRFGYWYCDSCSKRNTLCCFCNKPMKSLAISMLNCGHEGHFECLKKW 1303
W CD C + ++C C+ +K L + C H GH + + KW
Sbjct: 731 ------------------WVCDRCHRCASMCAVCHHVVKGLFVWCQGCSHGGHLQHIMKW 772
Query: 1304 FFDENMDVCPLGC 1316
E CP GC
Sbjct: 773 L--EGSSHCPAGC 783
>SPAC29A4.18 [B] KOG0264 Nucleosome remodeling factor subunit CAF1/NURF55/MSI1
Length = 431
Score = 58.5 bits (140), Expect = 7e-08
Identities = 45/159 (28%), Positives = 76/159 (47%), Gaps = 28/159 (17%)
Query: 210 TSAIDNPVVTS--LSEHTRSINSVDFNMVQTSLLISGGQDGCIKIWDLRSPKISTTRS-- 265
+SA ++P+ L++HT+ SV +N + L+SG QD + WDL + S + S
Sbjct: 167 SSASESPLKPKYRLTKHTQPCTSVCWNFLSKGTLVSGSQDATLSCWDLNAYNESDSASVL 226
Query: 266 DVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFK----FASVHDSGLLLKFDLRQPNQA 321
V I++ + DV++ H+K ASV L D+R+P+ +
Sbjct: 227 KVHISSHEKQVSDVRF----------------HYKHQDLLASVSYDQYLHVHDIRRPDAS 270
Query: 322 EK---KINAHSGPALCLNWHPHQDYIISG-GRDGKCCLW 356
K ++AHSGP + ++PH D+I++ D LW
Sbjct: 271 TKPARSVHAHSGPIHSVAFNPHNDFILATCSTDKTIALW 309
>ECU07g0750 [B] KOG0264 Nucleosome remodeling factor subunit CAF1/NURF55/MSI1
Length = 384
Score = 58.5 bits (140), Expect = 7e-08
Identities = 46/182 (25%), Positives = 78/182 (42%), Gaps = 20/182 (10%)
Query: 187 YNHKN--YVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSINSVDFNMVQTSLLISG 244
+NH N +A CG V ++D+++ S+ +P V L H ++N F+ LL S
Sbjct: 166 WNHLNPGELAGCGEGGEVCVFDVSQESSSISPTVV-LRRHETAVNDCAFSFFDKKLLSSA 224
Query: 245 GQDGCIKIWDLRSPKISTTRSDVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFKFASV 304
G G + +WD RS + + I V++ P D N + A+
Sbjct: 225 GDGGMVVLWDTRSEDCIHAIEEAH----TSDILSVRFSPL-----DGNVI-------ATS 268
Query: 305 HDSGLLLKFDLRQPNQAEKKINAHSGPALCLNWHPHQDYII-SGGRDGKCCLWYVGDKSN 363
G + +D R +Q + HS + + W PH D ++ SG D + +W +G
Sbjct: 269 SCDGSVKVWDRRSLSQPLHILLGHSKDVVSVEWSPHNDKVLASGSTDRRVIVWDLGQAGA 328
Query: 364 QV 365
+V
Sbjct: 329 EV 330
>YDL195w [U] KOG0307 Vesicle coat complex COPII subunit SEC31
Length = 1273
Score = 55.8 bits (133), Expect = 4e-07
Identities = 77/295 (26%), Positives = 119/295 (40%), Gaps = 42/295 (14%)
Query: 90 SSFDKRRTFHGA--KYSLSIGKEVSSIDKINSPESRSL----IIAGKSHLGIYTFDEDSK 143
+ F + TF + K L + VS N SL ++A S I + DSK
Sbjct: 5 AEFSRTATFAWSHDKIPLLVSGTVSGTVDANFSTDSSLELWSLLAADSEKPIASLQVDSK 64
Query: 144 TITNVHDFLQTAKTNTGITKNTSSTLRRTTKKISTISDVKAGFYNHK------------- 190
N D+ K G N S L T + + I+ + A F NH
Sbjct: 65 F--NDLDWSHNNKIIAGALDNGSLELYSTNEANNAINSM-ARFSNHSSSVKTVKFNAKQD 121
Query: 191 NYVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSINSVD------FNMVQTSLLISG 244
N +A G + + I+D+NK + ++P + +S++SVD +N + S
Sbjct: 122 NVLASGGNNGEIFIWDMNKCT--ESPSNYTPLTPGQSMSSVDEVISLAWNQSLAHVFASA 179
Query: 245 GQDGCIKIWDLRSPKISTTRSDVSINTG-SDSIRDVKWMPSYEFSNDTNGLSNRHFKFAS 303
G IWDL++ K S S N+G + V+W P N T + S
Sbjct: 180 GSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWHPK----NSTRVATAT----GS 231
Query: 304 VHDSGLLLKFDLRQPNQAEKKIN-AHSGPALCLNW-HPHQDYIISGGRDGKCCLW 356
+D +L+ +DLR N + +N H L L+W H + ++S GRD LW
Sbjct: 232 DNDPSILI-WDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDNTVLLW 285
>Hs5031817 [D] KOG0267 Microtubule severing protein katanin p80 subunit B
(contains WD40 repeats)
Length = 655
Score = 55.1 bits (131), Expect = 7e-07
Identities = 57/227 (25%), Positives = 92/227 (40%), Gaps = 42/227 (18%)
Query: 159 TGITKNTSSTLRRTTKKISTISDVKAGFYNHKNYVAICGTSTSVAIYDINKTSAIDNPVV 218
T + T+ L+ S +S + G + + +A G V ++ INK + I
Sbjct: 3 TPVVTKTAWKLQEIVAHASNVSSLVLGKASGR-LLATGGDDCRVNLWSINKPNCI----- 56
Query: 219 TSLSEHTRSINSVDFNMVQTSLLISGGQDGCIKIWDLRSPKISTTRSDVSINTGSDSIRD 278
SL+ HT + SV N + L+++G Q G I++WDL + KI T + N I
Sbjct: 57 MSLTGHTSPVESVRLNTPE-ELIVAGSQSGSIRVWDLEAAKILRTLMGLKAN-----ICS 110
Query: 279 VKWMPSYEF----SNDTN------------------GLSNRHFKF-------ASVHDSGL 309
+ + P EF S DTN + R +F AS D
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 310 LLKFDLRQPNQAEKKINAHSGPALCLNWHPHQDYIISGGRDGKCCLW 356
+ +DL + + H+GP + +HP++ + SG DG W
Sbjct: 171 VKLWDL-TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFW 216
>Hs14149696 [U] KOG0307 Vesicle coat complex COPII subunit SEC31
Length = 1179
Score = 55.1 bits (131), Expect = 7e-07
Identities = 43/148 (29%), Positives = 68/148 (45%), Gaps = 21/148 (14%)
Query: 197 GTSTSVAIYDINKT-SAIDNPVVTSLSEHTRSINSVDFNMVQTSLLISGGQDGCIKIWDL 255
G + + +Y++ S+ PV+ +HT ++ ++D N Q +LL SG D I IWDL
Sbjct: 92 GDNGMLILYNVTHILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDL 151
Query: 256 RSPKISTTRSDVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFK--FASVHDSGLLLKF 313
+ + T S D I+ + W NR + +S H SG + +
Sbjct: 152 NNLNVPMTLGSKSQQPPED-IKALSW--------------NRQAQHILSSAHPSGKAVVW 196
Query: 314 DLRQPNQAEKKINAHSGPALC--LNWHP 339
DLR+ N+ K++ HS C L WHP
Sbjct: 197 DLRK-NEPIIKVSDHSNRMHCSGLAWHP 223
>YBR195c [B] KOG0264 Nucleosome remodeling factor subunit CAF1/NURF55/MSI1
Length = 422
Score = 53.9 bits (128), Expect = 2e-06
Identities = 58/233 (24%), Positives = 92/233 (38%), Gaps = 63/233 (27%)
Query: 187 YNHKNYVAICGTSTSVAIYDINKT---------SAIDNPVVTSL---------------- 221
Y +N I G S+ AIY ++T S I +P T L
Sbjct: 137 YLPQNPDIIAGASSDGAIYIFDRTKHGSTRIRQSKISHPFETKLFGSHGVIQDVEAMDTS 196
Query: 222 SEHTRSINSVDFNMVQTSLLISGGQDGCIKIWDLRSPKISTTRSD---VSINTGSDSIRD 278
S S+ +N+ Q +LL+S +G +++WD++ D VSIN+ ++ D
Sbjct: 197 SADINEATSLAWNLQQEALLLSSHSNGQVQVWDIKQYSHENPIIDLPLVSINSDGTAVND 256
Query: 279 VKWMPSYE--FSNDTNG---------------LSNR------------HFK----FASVH 305
V WMP+++ F+ T G SNR ++K AS
Sbjct: 257 VTWMPTHDSLFAACTEGNAVSLLDLRTKKEKLQSNREKHDGGVNSCRFNYKNSLILASAD 316
Query: 306 DSGLLLKFDLRQPNQAEKKINAHSGPALCLNWHPHQDYII--SGGRDGKCCLW 356
+G L +D+R N++ H L W P+ D ++ +G DG LW
Sbjct: 317 SNGRLNLWDIRNMNKSPIATMEHGTSVSTLEWSPNFDTVLATAGQEDGLVKLW 369
>Hs7705258 [U] KOG0307 Vesicle coat complex COPII subunit SEC31
Length = 1181
Score = 52.8 bits (125), Expect = 4e-06
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 22/148 (14%)
Query: 197 GTSTSVAIYDINKTSAIDNPVVTSLSE-HTRSINSVDFNMVQTSLLISGGQDGCIKIWDL 255
G + ++ +YD +K A D VV + ++ HT + ++D N+ QT+L+ SG + I IWDL
Sbjct: 93 GENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDL 152
Query: 256 RSPKISTTRSDVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFK--FASVHDSGLLLKF 313
+ +T + + + I + W NR + AS SG +
Sbjct: 153 NN--FATPMTPGAKTQPPEDISCIAW--------------NRQVQHILASASPSGRATVW 196
Query: 314 DLRQPNQAEKKINAHSGPALC--LNWHP 339
DLR+ N+ K++ HS C L WHP
Sbjct: 197 DLRE-NEPIIKVSDHSNRMHCSGLAWHP 223
>CE28516 [S] KOG0269 WD40 repeat-containing protein
Length = 3901
Score = 52.8 bits (125), Expect = 4e-06
Identities = 43/186 (23%), Positives = 84/186 (45%), Gaps = 22/186 (11%)
Query: 189 HKNYVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSINSVDFNMVQTSLLISGGQDG 248
+ Y+A ++ S+ ++I++ + + H RS +D++ +L+SG +D
Sbjct: 114 YDQYIATTSSNGSIVCWNISRRNK------SVFKSHERSATCLDWHATTPYILVSGSRDC 167
Query: 249 CIKIWDLRSPKISTTRSDVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFKFASVHDSG 308
+K +D+R + + +SIRDV + F + F + D G
Sbjct: 168 TVKSYDMR---VKDNHQLTFSDRNCESIRDVAMCKAPGFDD----------YFFTGDDGG 214
Query: 309 LLLKFDLRQPNQAEKKINAHSGPALCLNWHPHQDYIIS--GGRDGKCCLW-YVGDKSNQV 365
+L +DLRQ + + AH L+ +PH +I+ GGRD +W + G + N++
Sbjct: 215 VLRLWDLRQTRRWVFQKVAHRSFVSTLSLNPHNRTLIATGGGRDKMVKIWEWTGPELNRI 274
Query: 366 GNISST 371
+ +T
Sbjct: 275 SVVETT 280
Score = 52.4 bits (124), Expect = 5e-06
Identities = 42/178 (23%), Positives = 71/178 (39%), Gaps = 25/178 (14%)
Query: 1141 WSSRRLIHQLYEQSVASGNILLTMAILLLF-QDMFQLVDTETVKNSIAEFTELLHRYELF 1199
WS I++L G++ AI ++ + + VD TV I + E+LHR ELF
Sbjct: 679 WSPMLEIYRLLLYHAEQGDMQTCAAISMVCGKRLLDAVDPYTVNGWIQCYMEMLHRLELF 738
Query: 1200 EIAAELMKNCPYEDIXXXXXXXXXIQLFCDKCNKPLVNESSKEKIIKERLEGNSSAMSRF 1259
+ A++ K CP + I IQL C+ +VN +
Sbjct: 739 LVCAKIRKYCPLDSISSVSRENTTIQLAHADCDALIVNGRCTK----------------- 781
Query: 1260 GYWYCDSCSKRNTLCCFCNKPMKSLAISMLNCGHEGHFECLKKWFFDENMDVCPLGCP 1317
C++ ++ + C C + + CGH H + +W F + + +GCP
Sbjct: 782 ----CEALAQAD--CTVCRFGIVGMTFQCNVCGHCMHTDHAYQW-FQKTKECAFVGCP 832
>Hs7662370 [U] KOG0307 Vesicle coat complex COPII subunit SEC31
Length = 1220
Score = 52.4 bits (124), Expect = 5e-06
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 22/148 (14%)
Query: 197 GTSTSVAIYDINKTSAIDNPVVTSLSE-HTRSINSVDFNMVQTSLLISGGQDGCIKIWDL 255
G + ++ +YD +K A D VV + ++ HT + ++D N+ QT+L+ SG + I IWDL
Sbjct: 93 GENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDL 152
Query: 256 RSPKISTTRSDVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFK--FASVHDSGLLLKF 313
+ +T + + + I + W NR + AS SG +
Sbjct: 153 NN--FATPMTPGAKTQPPEDISCIAW--------------NRQVQHILASASPSGRATVW 196
Query: 314 DLRQPNQAEKKINAHSGPALC--LNWHP 339
DLR+ N+ K++ HS C L WHP
Sbjct: 197 DLRK-NEPIIKVSDHSNRMHCSGLAWHP 223
>CE27713 [A] KOG0265 U5 snRNP-specific protein-like factor and related
proteins
Length = 331
Score = 52.4 bits (124), Expect = 5e-06
Identities = 59/259 (22%), Positives = 108/259 (40%), Gaps = 47/259 (18%)
Query: 179 ISDVKAGFYNHKNYVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSINSVDFNMVQT 238
I +VK F +++ GT +V ++D+ S I N HT +NSVD N
Sbjct: 82 IMEVK--FNADSSHLVSAGTDKTVRVWDMETGSCIRN-----FKSHTDIVNSVDVNRRGP 134
Query: 239 SLLISGGQDGCIKIWDLRSPKIST------TRSDVSINTGSDSI---------------- 276
++ S DG + + D+RS + + ++ V+ N +D++
Sbjct: 135 QMICSASDDGTVMVHDMRSKEAAKKFICKYQQTAVTFNDAADNVICGGIDNQIKVWDMLR 194
Query: 277 RDVKWMPSYEFSNDTNGLS---NRHFKFASVHDSGLLLKFDLRQPNQAEKKINAHSGPA- 332
DV+++ S T+ LS N +F ++ D L+ +D+R A++ + + G +
Sbjct: 195 NDVRYVLSGHRDTITS-LSVSHNGNFLLSNSMDCS-LMSWDIRPFVPAQRLVARYQGASH 252
Query: 333 ------LCLNWHPHQDYIISGGRDGKCCLWYVGDKS---NQVGNISSTNLNSSNPATHNL 383
L W P +YI +G D +W ++ G++ S N + +P L
Sbjct: 253 NFEKNLLKCGWSPRDNYITAGSADRFVYVWNAKSRACVYKLPGHLGSVNCTALHPTQQIL 312
Query: 384 SSSYPLGLSNTLAFPELTI 402
S+ G T+ EL +
Sbjct: 313 LSA---GSDKTIFLGELDL 328
>CE24997 [S] KOG0290 Conserved WD40 repeat-containing protein AN11
Length = 478
Score = 51.6 bits (122), Expect = 8e-06
Identities = 45/190 (23%), Positives = 77/190 (39%), Gaps = 15/190 (7%)
Query: 200 TSVAIYDINKTSAIDNPVVTSLSEHTRSINSVDFNMVQTSLLISGGQDGCIKIWDLRSPK 259
T AI T+AID V T L H + + + F+ + S G DG ++++DLR +
Sbjct: 287 TGQAIGTTRPTAAIDGTVRTQLIAHDKEVFDISFSRGSAQIFASVGADGSLRLFDLRRLE 346
Query: 260 ISTTRSDVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFKFASVHDSGLLLKFDLRQPN 319
ST + D + P + + N + ++ DS +L DLR P
Sbjct: 347 HSTIMYE-----------DPQRQPLLRLAWNRN---DHNYIATFGQDSKEVLILDLRLPC 392
Query: 320 QAEKKINAHSGPALCLNWHPHQ-DYIISGGRDGKCCLWYVGDKSNQVGNISSTNLNSSNP 378
++ H L+W PH +I + G D + +W V + + + +
Sbjct: 393 TPVARLRNHEATINGLSWAPHSGSHICTAGDDYQALIWDVHEMPKPINDPILAYRAQAEV 452
Query: 379 ATHNLSSSYP 388
+ SSS+P
Sbjct: 453 NQIHWSSSFP 462
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.313 0.128 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,594,667
Number of Sequences: 60738
Number of extensions: 3137783
Number of successful extensions: 10924
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 10861
Number of HSP's gapped (non-prelim): 38
length of query: 1321
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1203
effective length of database: 23,222,132
effective search space: 27936224796
effective search space used: 27936224796
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)