ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5554 good E KOG0053 Amino acid transport and metabolism Cystathionine beta-lyases/cystathionine gamma-synthases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5554 1904841 1905980 380
(380 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR112c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 517 e-147
SPAC23A1.14c [E] KOG0053 Cystathionine beta-lyases/cystathionine... 278 1e-74
At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 157 3e-38
YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 142 1e-33
CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 139 9e-33
CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 127 2e-29
CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 127 2e-29
7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 124 2e-28
At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 123 5e-28
At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 121 2e-27
HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 120 4e-27
Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 120 4e-27
SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 101 2e-21
YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 88 2e-17
At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 74 3e-13
YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 73 6e-13
YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 64 3e-10
YLL058w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 56 1e-07
SPBC15D4.09c [E] KOG0053 Cystathionine beta-lyases/cystathionine... 54 4e-07
YJR130c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 54 5e-07
>YHR112c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 378
Score = 517 bits (1332), Expect = e-147
Identities = 244/378 (64%), Positives = 316/378 (83%), Gaps = 2/378 (0%)
Query: 1 MSLSTELVHADDKHNRVTDIVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAH 60
+ LST L+H DDK NRVTD+ PINV+TTFRY++ DLIPW ERE+ +EKKP+YSRLAH
Sbjct: 2 VDLSTALIHGDDKDNRVTDVAPPINVSTTFRYDDDDLIPWTERENLDFMEKKPVYSRLAH 61
Query: 61 PNSLRVESVLSKVLEGEAVVYANGLAAYFAMLTYYNPKRLFIGEGYHGCRSIADIHTRNW 120
PNS R+ES+ S++L+G AV+Y++GLAA++A + +YNPK++FIG+ YHG R+IA+I TRN+
Sbjct: 62 PNSTRLESIFSEILDGYAVIYSSGLAAFYAAMVHYNPKKIFIGQSYHGVRAIANILTRNY 121
Query: 121 NLEQHKLEIDEILQHAGKGDVVHIETPVNPYGTSFDIKAFADATHSKGAILVIDSTFAPP 180
+EQH LE +I + A +GD+VH+E+PVNPYGTS DI++ A H+KGA+L++DSTFA P
Sbjct: 122 GIEQHPLE--DIEKCASEGDIVHLESPVNPYGTSSDIESLARRAHAKGALLIVDSTFASP 179
Query: 181 PLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTNIANLEAF 240
PLQ W+FG D++L+SATKYFGGHSDLL+GVL VK++ + +L+ DRIYLGTN+ANLE+F
Sbjct: 180 PLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIYLGTNVANLESF 239
Query: 241 LLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPFVKEQLKGGY 300
+LLRSLRT+EMRI QSENATKLV +L +H+S+F+ VL+ ++HSSLQTE FVK+QL GGY
Sbjct: 240 MLLRSLRTYEMRITKQSENATKLVRFLSDHQSEFDKVLKTIYHSSLQTEEFVKKQLVGGY 299
Query: 301 GPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPYIIPTLIRVSVGVEN 360
GPVFA+TL +KEQC++ P L F HATSLGG+ESLVEWRA+TDPYI TLIRVSVG E+
Sbjct: 300 GPVFAITLYTKEQCKQLPLKLKYFHHATSLGGIESLVEWRAMTDPYIDQTLIRVSVGCES 359
Query: 361 VDDLIKDFANALKTLQGA 378
+DLIKD A+ALK LQ A
Sbjct: 360 ANDLIKDLASALKELQDA 377
>SPAC23A1.14c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 398
Score = 278 bits (711), Expect = 1e-74
Identities = 165/391 (42%), Positives = 229/391 (58%), Gaps = 25/391 (6%)
Query: 2 SLSTELVHADDKHNRVTDIVSPINVATTFRYEEVD--LIPWNE--REDFSVLEKKPIYSR 57
+LST ++HADD + D+ PI+++TT+ Y L P+ + EDF P Y+R
Sbjct: 15 TLSTNVLHADDAYALENDVAPPIHISTTYTYPGTPDTLQPFTKLAEEDF------PYYAR 68
Query: 58 LAHPNSLRVESVLSKVLEGEAVVYANGLAAYFAMLTYYNPKRLFIGE----GYHGCRSIA 113
++ N R E+ LS VL +VVY++GLAA + +L+Y NPK + + + GY G I
Sbjct: 69 ISGNNVDRAEASLSSVLGAPSVVYSSGLAAIYGLLSYLNPKHIAVHKPGFGGYSGTIQII 128
Query: 114 DIHTRNWNLEQHKLEIDEILQHAGKGDVVHIETPVNPYGTSFDIKAFADATHSKGAILVI 173
R LE ID G+GDV+ +ETP+NP G +FDI + + KGAILV+
Sbjct: 129 ARINRLTGLETSF--IDGKCDAIGEGDVIWLETPLNPLGIAFDIPFYKELAKKKGAILVV 186
Query: 174 DSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTN 233
DSTFAPPP+Q+ G D ++HSATKY GHSD+LAGV A KD+ L+ DR YLGT
Sbjct: 187 DSTFAPPPIQDALVLGADYVVHSATKYLAGHSDVLAGVTASKDRSKILDLKADRAYLGTI 246
Query: 234 IANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFE---------GVLEGVFHS 284
+ +AFLLLRSLRTF +RI SEN + +L + +D + ++ V+H+
Sbjct: 247 LHPQQAFLLLRSLRTFPLRIAKHSENGFLVAQHLNKLATDEQFATSLGIDSSLILEVYHN 306
Query: 285 SLQTEPFVKEQLKGGYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTD 344
SLQT+ FV + L GG+ F+V L S + L F HATSLG VESL+EWR +TD
Sbjct: 307 SLQTKEFVAKNLTGGHASCFSVLLKSDTVAKHLCCELKYFHHATSLGSVESLIEWRRMTD 366
Query: 345 PYIIPTLIRVSVGVENVDDLIKDFANALKTL 375
I P L+R+S+G+E+ DLI D +L
Sbjct: 367 SKIDPRLVRLSIGIEDAADLIADLNRVFASL 397
>At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 464
Score = 157 bits (396), Expect = 3e-38
Identities = 115/395 (29%), Positives = 201/395 (50%), Gaps = 41/395 (10%)
Query: 2 SLSTELVHADDKHNRVTDIVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPI-YSRLAH 60
S+ST LV+ D+K + + +P+ TF+ S +E P Y+R +
Sbjct: 86 SVSTLLVNLDNKFDPFDAMSTPLYQTATFKQP-------------SAIENGPYDYTRSGN 132
Query: 61 PNSLRVESVLSKVLEGE-AVVYANGLAAYFAMLTYY-NPKRLFIGEGYHGC--RSIADIH 116
P +ES+L+K+ + + A + +G+AA A+ N + + G+ +G R ++ +
Sbjct: 133 PTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVV 192
Query: 117 TRNWNLEQ--HKLEIDEILQHAG-KGDVVHIETPVNPYGTSFDIKAFADATHSKGAILVI 173
R+ + + + ++DE+ G + +V +E+P NP DI+ ++ H++GA++++
Sbjct: 193 PRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLV 252
Query: 174 DSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTN 233
D++ P L P + G D+++HSATK+ GHSD++AGVLAVK +++A ++ + G+
Sbjct: 253 DNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSG 312
Query: 234 IANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEP--- 290
+A + +L LR ++T +RI+ Q ENA K+ YL H ++ V+++ L P
Sbjct: 313 LAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPR-----VKKVYYAGLPDHPGHH 367
Query: 291 FVKEQLKGGYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPYIIPT 350
Q KG G VF+ S + + F A S G V+SL+ IP
Sbjct: 368 LHFSQAKGA-GSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPA 426
Query: 351 -----------LIRVSVGVENVDDLIKDFANALKT 374
L+R+S G+E+VDDLI D A KT
Sbjct: 427 EVREARGLTEDLVRISAGIEDVDDLISDLDIAFKT 461
>YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 394
Score = 142 bits (357), Expect = 1e-33
Identities = 116/398 (29%), Positives = 193/398 (48%), Gaps = 45/398 (11%)
Query: 4 STELVHADDKHNRVTDIVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPNS 63
+T+ +HA + + ++ PI+++TTF+ P N + YSR +PN
Sbjct: 10 ATKAIHAGEHVDVHGSVIEPISLSTTFKQSS----PANPIGTYE-------YSRSQNPNR 58
Query: 64 LRVESVLSKVLEGE-AVVYANGLAAYFAMLTYY--NPKRLFIGEGYHGCR----SIADIH 116
+E ++ + + + +++G A +L + IG+ Y G +A+ H
Sbjct: 59 ENLERAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAH 118
Query: 117 TRNWNLEQHKL-EIDEILQHAGKGDVVHIETPVNPYGTSFDIKAFADAT--HSKG--AIL 171
+ L ++ ++++ K +V IETP NP DI+ AD H+ G IL
Sbjct: 119 GVETSFTNDLLNDLPQLIKENTK--LVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVIL 176
Query: 172 VIDSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLG 231
V+D+TF P + NP +FG D+++HSATKY GHSD++ GVLA +K + +L+ + +G
Sbjct: 177 VVDNTFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIG 236
Query: 232 TNIANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPF 291
+ +A+L R L+T +R++ + +A K+ +L K + + V + L+T P
Sbjct: 237 AIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKEN----VVAVNYPGLKTHPN 292
Query: 292 VKEQLKG-----GYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPY 346
LK G G + E KF F A SLGG+ESL+E A+
Sbjct: 293 YDVVLKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHG 352
Query: 347 IIP-----------TLIRVSVGVENVDDLIKDFANALK 373
IP L+R+SVG+E+ DDL++D ALK
Sbjct: 353 GIPKEAREASGVFDDLVRISVGIEDTDDLLEDIKQALK 390
>CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 139 bits (349), Expect = 9e-33
Identities = 107/382 (28%), Positives = 186/382 (48%), Gaps = 45/382 (11%)
Query: 20 IVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPNSLRVESVLSKVLEGE-A 78
+V PI ++T+R++ VD +NE + +Y R +P + VE V++++ G +
Sbjct: 82 VVVPIYHSSTYRFKTVD--QFNEDNHGANF----VYRRCGNPTTENVEVVINEIEGGAGS 135
Query: 79 VVYANGLAAYFAMLTYY---NPKRLFIGEGYHGCRSIADIHTRNWNLEQHKLEIDEILQH 135
++Y +GLAA A+ + + + Y G S + + +E +++++
Sbjct: 136 LLYNSGLAAISAVFLEFLSSGAHMIVMNPIYSGTSSFINETLARFGVEITSVDVEKEKDF 195
Query: 136 AGKGD--------VVHIETPVNPYGTSFDIKAFADATHSKGAILVIDSTFAPPPLQNPWD 187
AG + +++ E+ NP DI + + +D+TF+ P P
Sbjct: 196 AGAVEKAIRPNTKMIYFESIANPTMAVPDILGTIEVAKKYKILTCLDATFSSPYNIQPLK 255
Query: 188 FGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTNIANLEAFLLLRSLR 247
G D+ LHS +KY GGH+D++AGV+ V + KL+ ++ G++++ +A LL R L+
Sbjct: 256 LGADISLHSCSKYIGGHTDVIAGVVTVSSYDNWKKLKLQQLTTGSSLSPYDAALLTRGLK 315
Query: 248 TFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEP---FVKEQLKGGYGPVF 304
T +R+ SENA K +L H +E VF+ L + P + K+ +K + +
Sbjct: 316 TLGLRVDRISENAQKTAEFLESHPK-----VERVFYPGLPSHPQHQYAKQVMK-QFAGMI 369
Query: 305 AVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVE-----------WRALTDPYIIPTLIR 353
A + + E K + A SLGG ESL+E R L P + P L+R
Sbjct: 370 AFDVGTAENAIKLVE-------AISLGGTESLIEHPLSMSHGKHLLRYLDGPTVAPGLLR 422
Query: 354 VSVGVENVDDLIKDFANALKTL 375
SVG+ENV+D+I D +AL+ L
Sbjct: 423 FSVGIENVEDIIGDLNDALEKL 444
>CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 127 bits (320), Expect = 2e-29
Identities = 114/393 (29%), Positives = 180/393 (45%), Gaps = 39/393 (9%)
Query: 5 TELVHADDKHNR--VTDIVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPN 62
T+ VH + + + +V PI+++TT++ + N E K+ Y+R +P
Sbjct: 9 TDAVHVGQEPEQWDINQVVPPISMSTTYKQD-------NPGEP-----KRYDYARGGNPT 56
Query: 63 SLRVESVLSKVLEG--EAVVYANGLAAYFAMLTYYNP-KRLFIGEGYHG--CRSIADIHT 117
++ L+ LEG +++GLAA A++ N + + +G R I I
Sbjct: 57 RDVLQKNLA-ALEGAKHCQAFSSGLAASSAVINLLNHGDHIVCSDDVYGGTIRYIRQIAV 115
Query: 118 RNWNLEQHKLEIDEI--LQHAGKGD--VVHIETPVNPYGTSFDIKAFADATHSKGA--IL 171
+ + +E +++ ++ L+ A K + +V E+P NP DI A ++
Sbjct: 116 KKYGMEVDSVDLTDVQNLEKAIKPNTKMVWFESPSNPLLKVVDIAAVVQTAKRANPEIVV 175
Query: 172 VIDSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLG 231
V+D+TF P Q P G D+ +HS TKY GHSD++ G + E L + +G
Sbjct: 176 VVDNTFMTPYFQRPLSLGADIAVHSITKYINGHSDIIMGAAITNNDEFQQHLHFMQRAIG 235
Query: 232 TNIANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPF 291
+ + FL+ R L+T +R++ ENA + +L H E VL S Q
Sbjct: 236 GVPSPFDCFLVNRGLKTLHVRMKAHFENALAIAKFLEAHDC-IESVLYPALPSHPQHTVH 294
Query: 292 VKEQLKGGYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPYIIPT- 350
VK Q KG G + Q R F L F A SLGG ESL E ++ +P+
Sbjct: 295 VK-QTKGMSGMISFYLKGELCQSRAFLSALKVFTLAESLGGCESLAELPSIMTHASVPSA 353
Query: 351 ----------LIRVSVGVENVDDLIKDFANALK 373
LIR+SVG+E++DDLI D ALK
Sbjct: 354 TRAELGITDNLIRISVGIEDLDDLIADLDQALK 386
>CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 127 bits (320), Expect = 2e-29
Identities = 111/378 (29%), Positives = 176/378 (46%), Gaps = 35/378 (9%)
Query: 17 VTDIVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPNSLRVESVLSKVLEG 76
+ +V PI++++T++ + N E K YSR +P ++ L+ + +
Sbjct: 23 MNQVVPPISLSSTYKQD-------NPGEP-----KGHDYSRAGNPTRDVLQKNLAALEDA 70
Query: 77 E-AVVYANGLAAYFAMLTY--YNPKRLFIGEGYHGC-RSIADIHTRNWNLEQHKLEIDEI 132
+ V+++GLAA A++ Y + + Y G R I + N LE +++ ++
Sbjct: 71 KHCQVFSSGLAATSAIINLLKYGDHIVCSDDVYGGTQRYIRRVAVPNHGLEVDSVDLTDV 130
Query: 133 --LQHAGKGD--VVHIETPVNPYGTSFDIKAFADATHSKGA--ILVIDSTFAPPPLQNPW 186
L+ A K + +V E+P NP DI A ++V+D+TF P Q P
Sbjct: 131 QNLEKAIKPNTKMVWFESPSNPLLKVVDIAAVVQTAKKANPEIVVVVDNTFMSPYFQRPI 190
Query: 187 DFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTNIANLEAFLLLRSL 246
G DV++HS TKY GHSD++ G + + E L ++ +G + + FL+ R L
Sbjct: 191 SLGADVVVHSITKYINGHSDVVMGAVITDNDEFQQHLFFMQLAVGAVPSPFDCFLVNRGL 250
Query: 247 RTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPFVKEQLKGGYGPVFAV 306
+T +R++ ENA + YL E E VL S Q E K Q KG G +
Sbjct: 251 KTLHIRMRAHYENALAVAKYL-EANDRIESVLYPALPSHPQHEVHEK-QTKGMSGMISFY 308
Query: 307 TLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPYIIP-----------TLIRVS 355
++ R F L F A SLGG ESL E ++ +P LIR+S
Sbjct: 309 LKGELQESRAFLSALKVFTLAESLGGYESLAELPSIMTHASVPAETRIVLGITDNLIRIS 368
Query: 356 VGVENVDDLIKDFANALK 373
VG+E++DDL+ D ALK
Sbjct: 369 VGIEDLDDLVADLDQALK 386
>7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 393
Score = 124 bits (311), Expect = 2e-28
Identities = 105/380 (27%), Positives = 185/380 (48%), Gaps = 46/380 (12%)
Query: 20 IVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPNSLRVESVLSKVLEGE-A 78
++ PI+++TTF+ + E + YSR +P +E+ + + +
Sbjct: 29 VIPPISLSTTFKQDAP-----GEHRGYE-------YSRSGNPTRNVLETCFAALDNAKYG 76
Query: 79 VVYANGLAAYFAMLTYYNP-KRLFIGEGYHGC--RSIADIHTRNWNLEQHKLEID----E 131
+ +++GL A A+LT + + +G+ +G R I + TR L +D +
Sbjct: 77 LTFSSGLGATTAVLTMLSSGDHIIMGDDVYGGTNRLIRQVATR---LGISATFVDPTKLD 133
Query: 132 ILQHAGKGD--VVHIETPVNPYGTSFDIKAFADATHS--KGAILVIDSTFAPPPLQNPWD 187
+++ + K + +V IE+P NP DI+A A H + +L +D+TF Q P +
Sbjct: 134 LIKSSIKPETKLVWIESPTNPLVKVADIEAIAQLVHGVREDIVLAVDNTFLTSYFQRPLE 193
Query: 188 FGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTNIANLEAFLLLRSLR 247
G D++ +S TKY GH+D++ G + + +++ L+ + +G + + + + RSL+
Sbjct: 194 LGADLVCYSLTKYMNGHTDVVMGGITMNSEKLYKSLKFLQNAVGIVPSPFDCYQVNRSLK 253
Query: 248 TFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPFVKEQLKG--GYGPVFA 305
T +R++ +NA K+ YL + +E V H SL + P K LK GY VF+
Sbjct: 254 TLSLRMEQHQKNALKVAKYL-----ETNPFVEKVLHPSLPSHPQHKIALKQAYGYSGVFS 308
Query: 306 VTLNSK-EQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPYIIPT-----------LIR 353
+ + + F + L F A SLGG ESL E ++ +P L+R
Sbjct: 309 FYIKGELKHSSAFLKALKVFTLAESLGGYESLAELPSIMTHASVPAEDRKTLGITDGLVR 368
Query: 354 VSVGVENVDDLIKDFANALK 373
+SVG+E+ DDLIKD AL+
Sbjct: 369 LSVGLEDADDLIKDLEQALE 388
>At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 412
Score = 123 bits (308), Expect = 5e-28
Identities = 112/394 (28%), Positives = 180/394 (45%), Gaps = 39/394 (9%)
Query: 6 ELVHADDKHNRVTDIVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPNSLR 65
E + D K + +T +V +N T F + +LI + E+ + E Y+R +P ++
Sbjct: 34 ERLRRDMKTSSITTLV--VNTTTYFFKDTTELIDFKEKR-IDLYE----YARYGNPTTMA 86
Query: 66 VESVLSKVLEG--EAVVYANGLAAYFAMLTYYNPKRLFI---GEGYHGCRSIADIHTRNW 120
+E +S VLEG +V A+G+ A ML P I + Y R +
Sbjct: 87 LEEKIS-VLEGAESTLVMASGMYASNVMLLALVPTNGHIVATKDCYKETRIFMENFLTKL 145
Query: 121 NLEQHKLEIDEI-----LQHAGKGDVVHIETPVNPYGTSFDIKAFADATHSKGAILVIDS 175
+ ++ D+I L + + + E+P NP+ DIK + H +G ++ ID+
Sbjct: 146 GITVTFIDSDDIAGLQTLVNNHEVSLFFTESPTNPFLRCVDIKLVSKICHRRGTLVCIDA 205
Query: 176 TFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTNIA 235
T A P Q G D++ HSATKY GGH+D LAG ++ E+ SK+R LG +
Sbjct: 206 TIATPINQKTLALGADLVHHSATKYIGGHNDFLAGSIS-GSMELVSKIRNLHKLLGGTLN 264
Query: 236 NLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEP---FV 292
A+LL+R ++T +R++ Q+ K+ L H + V++ L + P
Sbjct: 265 PNAAYLLIRGMKTMHLRVRQQNSTGMKMAQVLEAHPK-----VSRVYYLGLPSHPEHLIA 319
Query: 293 KEQLKGGYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPYIIP--- 349
K Q+ G G + + KF L A S GG ESLV+ A T + IP
Sbjct: 320 KRQMTGIGGLISFEIDGDLKTTIKFIDALKIPYLAASFGGCESLVDQLA-TGIWDIPREE 378
Query: 350 --------TLIRVSVGVENVDDLIKDFANALKTL 375
L+R S G+E+ +D+ D AL+T+
Sbjct: 379 RLKDGFQDNLVRFSFGIEDFEDIKADVLQALETI 412
>At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 563
Score = 121 bits (303), Expect = 2e-27
Identities = 109/396 (27%), Positives = 178/396 (44%), Gaps = 40/396 (10%)
Query: 8 VHADDKHNR--VTDIVSP--INVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPNS 63
VHA ++ R VTD ++ +N + F + +LI + E+ S Y R +P +
Sbjct: 180 VHAGERLGRGIVTDAITTPVVNTSAYFFKKTAELIDFKEKRSVSFE-----YGRYGNPTT 234
Query: 64 LRVESVLSKVLEG--EAVVYANGLAAYFAMLTYYNPKRLFI---GEGYHGCRSIADIHTR 118
+ +E +S LEG +V A+G+ A ML P I + Y R +
Sbjct: 235 VVLEDKIS-ALEGAESTLVMASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFMENFLP 293
Query: 119 NWNLEQHKLEIDEILQ-----HAGKGDVVHIETPVNPYGTSFDIKAFADATHSKGAILVI 173
+ ++ +I + K + E+P NP+ DI+ + H +G ++ I
Sbjct: 294 KLGITVTVIDPADIAGLEAAVNEFKVSLFFTESPTNPFLRCVDIELVSKICHKRGTLVCI 353
Query: 174 DSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTN 233
D TFA P Q G D+++HSATKY GGH+D+LAG + K + S++R LG
Sbjct: 354 DGTFATPLNQKALALGADLVVHSATKYIGGHNDVLAGCICGSLK-LVSEIRNLHHVLGGT 412
Query: 234 IANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEP--- 290
+ A+L++R ++T +R+Q Q+ A ++ L H + V++ L + P
Sbjct: 413 LNPNAAYLIIRGMKTLHLRVQQQNSTAFRMAEILEAHPK-----VSHVYYPGLPSHPEHE 467
Query: 291 FVKEQLKGGYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPYIIP- 349
K Q+ G G V E KF L A S GG ES+V+ A+ + +P
Sbjct: 468 LAKRQMTGFGGVVSFEIDGDIETTIKFVDSLKIPYIAPSFGGCESIVDQPAIMSYWDLPQ 527
Query: 350 ----------TLIRVSVGVENVDDLIKDFANALKTL 375
L+R S GVE+ +D+ D AL+ +
Sbjct: 528 EERLKYGIKDNLVRFSFGVEDFEDVKADILQALEAI 563
>HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 120 bits (300), Expect = 4e-27
Identities = 112/395 (28%), Positives = 184/395 (46%), Gaps = 43/395 (10%)
Query: 4 STELVHADDKHNRVTD--IVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHP 61
+T+ +H + T +V PI+++TTF+ + F YSR +P
Sbjct: 19 ATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAP-----GQHSGFE-------YSRSGNP 66
Query: 62 NSLRVESVLSKVLEGE--AVVYANGLAAYFAM--LTYYNPKRLFIGEGYHGCRSIADIHT 117
+E ++ L+G + +A+GLAA + L + + + + Y G
Sbjct: 67 TRNCLEKAVA-ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVA 125
Query: 118 RNWNLEQHKLEIDEI--LQHA--GKGDVVHIETPVNPYGTSFDIKAFADATHSKG-AILV 172
+ L+ ++ +I L+ A + +V IETP NP DI+ A H G ILV
Sbjct: 126 SEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV 185
Query: 173 IDSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGT 232
+D+TF P Q P G D+ ++SATKY GHSD++ G+++V + + ++LR + LG
Sbjct: 186 VDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGA 245
Query: 233 NIANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEP-- 290
+ ++ +L R L+T +R++ +N + +L + +E V + L + P
Sbjct: 246 VPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFL-----ESNPWVEKVIYPGLPSHPQH 300
Query: 291 -FVKEQLKGGYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPY--- 346
VK Q G G V + + F + L F A SLGG ESL E A+
Sbjct: 301 ELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVL 360
Query: 347 --------IIPTLIRVSVGVENVDDLIKDFANALK 373
I TLIR+SVG+E+ +DL++D ALK
Sbjct: 361 KNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALK 395
>Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 120 bits (300), Expect = 4e-27
Identities = 112/395 (28%), Positives = 184/395 (46%), Gaps = 43/395 (10%)
Query: 4 STELVHADDKHNRVTD--IVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHP 61
+T+ +H + T +V PI+++TTF+ + F YSR +P
Sbjct: 19 ATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAP-----GQHSGFE-------YSRSGNP 66
Query: 62 NSLRVESVLSKVLEGE--AVVYANGLAAYFAM--LTYYNPKRLFIGEGYHGCRSIADIHT 117
+E ++ L+G + +A+GLAA + L + + + + Y G
Sbjct: 67 TRNCLEKAVA-ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVA 125
Query: 118 RNWNLEQHKLEIDEI--LQHA--GKGDVVHIETPVNPYGTSFDIKAFADATHSKG-AILV 172
+ L+ ++ +I L+ A + +V IETP NP DI+ A H G ILV
Sbjct: 126 SEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV 185
Query: 173 IDSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDKEVASKLRTDRIYLGT 232
+D+TF P Q P G D+ ++SATKY GHSD++ G+++V + + ++LR + LG
Sbjct: 186 VDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGA 245
Query: 233 NIANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEP-- 290
+ ++ +L R L+T +R++ +N + +L + +E V + L + P
Sbjct: 246 VPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFL-----ESNPWVEKVIYPGLPSHPQH 300
Query: 291 -FVKEQLKGGYGPVFAVTLNSKEQCRKFPQLLTCFQHATSLGGVESLVEWRALTDPY--- 346
VK Q G G V + + F + L F A SLGG ESL E A+
Sbjct: 301 ELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVL 360
Query: 347 --------IIPTLIRVSVGVENVDDLIKDFANALK 373
I TLIR+SVG+E+ +DL++D ALK
Sbjct: 361 KNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALK 395
>SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 429
Score = 101 bits (252), Expect = 2e-21
Identities = 107/409 (26%), Positives = 168/409 (40%), Gaps = 68/409 (16%)
Query: 23 PINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPNSLRVESVLSKVLEGEAVVY- 81
PI T++ + + D + F + E IYSR+ +P + E ++ + G A +
Sbjct: 29 PIYATTSYVFRDCD----HGGRLFGLQEPGYIYSRMMNPTADVFEKRIAALEHGAAAIAT 84
Query: 82 ANGLAAYFAMLTYY---NPKRLFIGEGYHGCRSIADIHTRNWNLEQHKLEIDEILQHAGK 138
++G +A F LT + Y G ++ + + + D+ A +
Sbjct: 85 SSGTSALFMALTTLAKAGDNIVSTSYLYGGTYNLFKVTLPRLGITTKFVNGDDPNDLAAQ 144
Query: 139 GD----VVHIETPVNPYGTSFDIKAFADATHSKGAILVIDSTFAPPP-LQNPWDFGVDVI 193
D V++E+ NP D + A+ H+ G L++D+TF L P D G D++
Sbjct: 145 IDENTKAVYVESIGNPMYNVPDFERIAEVAHAAGVPLMVDNTFGGGGYLVRPIDHGADIV 204
Query: 194 LHSATKYFGGHSDLLAGVLAVKDK--------------------------------EVAS 221
HSATK+ GGH + GV+ K A
Sbjct: 205 THSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEFNEPHPGYHGMVFTETFGNLAYAF 264
Query: 222 KLRTDRIY-LGTNIANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKS----DFEG 276
RT + +G N FLLL+ L T +R++ +NA L YL +H + G
Sbjct: 265 ACRTQTLRDVGGNANPFGVFLLLQGLETLSLRMERHVQNAFALAKYLEKHPKVNWVSYPG 324
Query: 277 VLEGVFHSSLQTEPFVKEQLKGGYGPVFAV-TLNSKEQCRKFPQLLTCFQHATSLGGVES 335
+ V H K+ LK GYG V + +Q RK L ++G ++
Sbjct: 325 LESHVSHK------LAKKYLKNGYGAVLSFGAKGGPDQSRKVVNALKLASQLANVGDAKT 378
Query: 336 LVEWRA------LTDPYIIPT-----LIRVSVGVENVDDLIKDFANALK 373
LV A LTD I LIRV+VG+E++DD+I DFA AL+
Sbjct: 379 LVIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHIDDIIADFAQALE 427
>YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 465
Score = 88.2 bits (217), Expect = 2e-17
Identities = 103/415 (24%), Positives = 176/415 (41%), Gaps = 61/415 (14%)
Query: 3 LSTELVHADDKHNRVTDIVSPINVATTFRYEEVDLIPWNEREDFSVLEKKPIYSRLAHPN 62
L T +V+ ++++ + V P+ ++TTF+ VDL ED + YSR +P
Sbjct: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFK---VDL----NNEDAQNYD----YSRSGNPT 54
Query: 63 SLRVESVLSK---VLEGEAVVYANGLAAYFAML--------TYYNPKRLFIGEGYHGCRS 111
++ + K V + + ++G+ A +L T + + G+ +G
Sbjct: 55 RSVLQHQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQ 114
Query: 112 -----------IADIHTRNWNLEQHKLEIDEILQHAGKGDVVHIETPVNPYGTSFDIKAF 160
+H + E+ K + Q K D V +E+P NP DI
Sbjct: 115 RLLNFFKQQSHAVSVHVDTSDFEKFKT----VFQSLDKVDCVLLESPTNPLCKVVDIPRI 170
Query: 161 ADATH--SKGAILVIDSTFAPPPLQNPWDF--GVDVILHSATKYFGGHSDLLAGVLAVKD 216
S +V+D+T NP G DV+ SATKY GH DL+ GV+ K
Sbjct: 171 LRFVKCISPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKT 230
Query: 217 KEVASKLRTDRIYLGTNIANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEG 276
E+ASKL G ++ ++++LL+R L+T +R+ Q NA ++++ +E+ F+
Sbjct: 231 PEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNA-MILAHWLENSCGFKP 289
Query: 277 VLEGVFHSS----LQTEPFVK--EQLKGGYGPVFAVTLNSKEQCRKF--PQLLTCFQHAT 328
+ L++ P K + G G V + S E ++ + L+ +
Sbjct: 290 TRTNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTV 349
Query: 329 SLGGVESLVEW-----RALTDPYI------IPTLIRVSVGVENVDDLIKDFANAL 372
S G V SL+ A DP + L+R+ G+EN+ DL KD A+
Sbjct: 350 SFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
>At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 441
Score = 74.3 bits (181), Expect = 3e-13
Identities = 89/347 (25%), Positives = 149/347 (42%), Gaps = 61/347 (17%)
Query: 54 IYSRLAHPNSLRVESVLSKVLEGEAVVY--ANGLAAYFAML--------------TYYNP 97
+YSR +P L + ++ LEG Y ++G++A +++ T Y
Sbjct: 94 VYSRHFNPTVLNLSRQMA-ALEGTQAAYCTSSGMSAISSVMLQLCSSGGHVVAASTLYGG 152
Query: 98 KRLFIGEGYHGCRSIADIHTRNWNLEQHKLEIDEILQHAGKGDVVHIETPVNPYGTSFDI 157
+ H +I T ++ H + I++ G+ V++ E+ NP T DI
Sbjct: 153 THALLS---HFLPRTCNITTSFVDITDHGAVANAIVE--GRTQVLYFESVANPTLTVADI 207
Query: 158 KAFADATHSKGAILVIDSTFAPPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKD- 216
+ H KG +V+D+TFAP L +P G DV++HS +K+ G +D++AG + +
Sbjct: 208 PELSRMAHEKGVTVVVDNTFAPMVL-SPAKLGADVVVHSISKFISGGADIIAGAVCGSEN 266
Query: 217 --KEVASKLRTDRIYLGTNIANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDF 274
KE+ + LG + AF L + +R++ S A E D
Sbjct: 267 LVKEMMDLRGGSLMLLGPTMNAKVAFELSERIPHLGLRMREHSHRA----QVYAERMRDL 322
Query: 275 EGVLEGVFHSSLQTEPFVKEQLKG------GYGPVFAVTLNSKEQCRKFPQLLTCFQHAT 328
V + L+T P K KG GYG + ++ + ++E+ K L+ Q+AT
Sbjct: 323 G---MKVIYPGLETHPQHK-LFKGMVNRDYGYGGLLSIDMETEEKANK---LMAYLQNAT 375
Query: 329 -------SLGGVESLVEWRALT-----DPY------IIPTLIRVSVG 357
SLG E+L+ + DP I P L+R+SVG
Sbjct: 376 QFGFMAVSLGYYETLMSCSGSSTSSELDPSQKEAAGISPGLVRMSVG 422
>YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 73.2 bits (178), Expect = 6e-13
Identities = 96/390 (24%), Positives = 158/390 (39%), Gaps = 74/390 (18%)
Query: 54 IYSRLAHPNSLRVESVLSKVLEGEAVVYA--NGLAAYFAM---LTYYNPKRLFIGEGYHG 108
+YSR +P S +E ++ LEG A A +G AA L + + Y G
Sbjct: 55 VYSRFQNPTSNVLEERIA-ALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGG 113
Query: 109 CRSIADIHTRNWNLEQHKLEIDEILQHAGKGD----VVHIETPVNPYGTSFDIKAFADAT 164
+ I + + +E +E D + D V++ET NP D +
Sbjct: 114 TYNQFKISFKRFGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIA 173
Query: 165 HSKGAILVIDSTF-APPPLQNPWDFGVDVILHSATKYFGGHSDLLAGVLAVKDK------ 217
H G +V+D+TF A P +G D++ HSATK+ GGH + G++ K
Sbjct: 174 HKHGIPVVVDNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDY 233
Query: 218 ------------------------------EVASKLRTDRIYLGTNIANLEAFLLLRSLR 247
V ++L D LG + +FLLL+ +
Sbjct: 234 PEKFPQFSQPAEGYHGTIYNEAYGNLAYIVHVRTELLRD---LGPLMNPFASFLLLQGVE 290
Query: 248 TFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPFVKEQLKGGYGPVFAVT 307
T +R + ENA KL +L +S + + +S K+ L G+G V +
Sbjct: 291 TLSLRAERHGENALKLAKWL--EQSPYVSWVSYPGLASHSHHENAKKYLSNGFGGVLSFG 348
Query: 308 L----NSKEQCRKF----PQLLTCFQHATSL---GGVESLV------EWRALTDPY---- 346
+ N+ ++ F Q++ + A++L G ++LV + L D
Sbjct: 349 VKDLPNADKETDPFKLSGAQVVDNLKLASNLANVGDAKTLVIAPYFTTHKQLNDKEKLAS 408
Query: 347 -IIPTLIRVSVGVENVDDLIKDFANALKTL 375
+ LIRVSVG+E +DD+I DF + +T+
Sbjct: 409 GVTKDLIRVSVGIEFIDDIIADFQQSFETV 438
>YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 340
Score = 64.3 bits (155), Expect = 3e-10
Identities = 49/170 (28%), Positives = 83/170 (48%), Gaps = 4/170 (2%)
Query: 141 VVHIETPVNPYGTSFDIKAFADATHSKGAILVIDSTFAPPPLQNPWDFGVDVILHSATKY 200
V+ +E+P + DI A G ++D+T+A P + G+D+ + + TKY
Sbjct: 150 VIFLESPGSGTMEVQDIPALVSVAKKHGIKTILDNTWATPLFFDAHAHGIDISVEAGTKY 209
Query: 201 FGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTNIANLEAFLLLRSLRTFEMRIQTQSENA 260
GGHSDLL G LA ++E LR+ + + L LR +RT +R++ A
Sbjct: 210 LGGHSDLLIG-LASANEECWPLLRSTYDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKA 268
Query: 261 TKLVSYLIEHKSDFEGVLEGVFHSSLQTEPFVKEQLKGGYGPVFAVTLNS 310
L ++L ++ + E VL F E +V++ KG G +F++ L +
Sbjct: 269 LDLAAWL-GNRDEVEKVLHPAFEDCPGHEYWVRD-YKGSSG-LFSIVLKN 315
>YLL058w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 575
Score = 55.8 bits (133), Expect = 1e-07
Identities = 62/261 (23%), Positives = 115/261 (43%), Gaps = 39/261 (14%)
Query: 142 VHIETPVNPYGTSFDIKAFADATHSKGAILVIDSTFAPPPLQN-PWDFGVDVILHSATKY 200
V +ETP NP D+K G +VID T + P+ D++ S TK
Sbjct: 321 VFVETPSNPLLNMPDLKKLRSLADQYGFFIVIDDTIGGLNVDILPY---ADIVSTSLTKL 377
Query: 201 FGGHSDLLAGVLAVKDKEVASKLRTDRIYLGTNIANL----EAFLLLRSLRTFEMRIQTQ 256
F G S+++ G + + K + + N +L +A +L R+ R FE R
Sbjct: 378 FNGASNVMGGSVVLNPKSSLYPYARE-YFRSANFEDLLWCEDAIVLERNSRDFEDRTLRA 436
Query: 257 SENATKLVSYLIEHKSDFEG-VLEGVFHSSLQTEPFVKE-----QLKGGYGPVFAVTLNS 310
+ N L++ L+ + EG + + +++ ++ ++ + +GGYG +F+V +
Sbjct: 437 NANTGILLNDLLLPE---EGKICKKIYYPTVTSKETFENYESVRNERGGYGCLFSVAFFN 493
Query: 311 KEQCRKFPQLLTCFQ---------------HATSLGGVESLVEWRALTDPYIIPTLIRVS 355
+ + F L F+ H +E + ++ A P +IRVS
Sbjct: 494 EGDAKAFYDSLKVFKGPSNGTNFTLACPYVHLAHHSELEEVSKFGA------DPNIIRVS 547
Query: 356 VGVENVDDLIKDFANALKTLQ 376
VG+E++ L+K F++AL ++
Sbjct: 548 VGLEDIQWLLKVFSSALDVVK 568
>SPBC15D4.09c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 610
Score = 53.9 bits (128), Expect = 4e-07
Identities = 67/271 (24%), Positives = 109/271 (39%), Gaps = 44/271 (16%)
Query: 128 EIDEILQHAGKGDVVHIETPVNPYGTSFDIKAFADATHSKGAILVIDSTFAP------PP 181
E ++ L+ K + E P NP S D+ S +V+D T P
Sbjct: 357 EFEKRLESGEKVMALFCEFPSNPLLNSPDLVRIRKLADSYDFAVVVDETIGNFVNVEVLP 416
Query: 182 LQNPWDFGVDVILHSATKYFGGHSDLLAGVLAV--------KDKEVASKLRTDRIYLGTN 233
L DV++ S TK F G S+++ G + + + K+ L D +Y
Sbjct: 417 L-------ADVVVSSLTKIFSGDSNVMGGSMVLNPSSRYYSRIKDAMKALYEDLLY---- 465
Query: 234 IANLEAFLLLRSLRTFEMRIQTQSENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPFVK 293
+ +A L R+ R F R Q + NA + + L ++ ++ +++ T
Sbjct: 466 --DEDALTLERNSRDFAERSQVINHNAETICNLLYQNPK-----IKTLYYPKYNTSKEHF 518
Query: 294 EQLK---GGYGPVFAVTLNSKEQCRKF---------PQLLTCFQHATSLGGVESLVEWRA 341
E + GGYG + +V ++ E R+F P L T F A+ + E
Sbjct: 519 EACRRENGGYGGLLSVVFHNPEDARQFYDKIQVAKGPSLGTNFTLASPYAILAHYQELDW 578
Query: 342 LTDPYIIPTLIRVSVGVENVDDLIKDFANAL 372
+ I L+RVSVG+E + L F NAL
Sbjct: 579 AGENGIDRNLVRVSVGMEPSEHLKNVFINAL 609
>YJR130c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 639
Score = 53.5 bits (127), Expect = 5e-07
Identities = 63/255 (24%), Positives = 103/255 (39%), Gaps = 22/255 (8%)
Query: 142 VHIETPVNPYGTSFDIKAFADATHSKGAILVIDSTFAPPPLQNPWDFGVDVILHSATKYF 201
V IE P NP D++ + +V+D T + + D++ S TK F
Sbjct: 387 VFIEAPSNPLLKMGDLQELKRLSDLYSFYIVVDETVGGFVNIDVLPYA-DIVCSSLTKIF 445
Query: 202 GGHSDLLAGVLAVKDK----EVASKLRTDRIYLGTNIANLEAFLLLRSLRTFEMRIQTQS 257
G S+++AG L + + E A K + +A L R+ R F R +
Sbjct: 446 SGDSNVIAGSLVLNPRGKIYEFARKFMKTEDGYEDCLWCEDALCLERNSRDFVERTIKVN 505
Query: 258 ENATKLVSYLIEHKSDFEGVLEGVFHSSLQTEPF------VKEQLKGGYGPVFAVTLNSK 311
N L+ ++ + + +++ SL +E V GGYG +F++T +
Sbjct: 506 TNTDILLKRVL--LPQVGKLFKKIYYPSLTSEDTKRNYDSVMSTKDGGYGGLFSLTFFNI 563
Query: 312 EQCRKF---------PQLLTCFQHATSLGGVESLVEWRALTDPYIIPTLIRVSVGVENVD 362
E+ +KF P L T F A + E + + L+RVSVG+EN D
Sbjct: 564 EEAKKFFNNLELCKGPSLGTNFTLACPYAIIAHYQELDEVAQYGVETNLVRVSVGLENSD 623
Query: 363 DLIKDFANALKTLQG 377
L F A++ G
Sbjct: 624 VLCNVFQRAIEKALG 638
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,460,307
Number of Sequences: 60738
Number of extensions: 953363
Number of successful extensions: 2432
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2371
Number of HSP's gapped (non-prelim): 22
length of query: 380
length of database: 30,389,216
effective HSP length: 108
effective length of query: 272
effective length of database: 23,829,512
effective search space: 6481627264
effective search space used: 6481627264
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)