ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5602.1 suspect: Pn T KOG1187 Signal transduction mechanisms Serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5602.1 1925088 1925327 80
(80 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
At4g32710 [T] KOG1187 Serine/threonine protein kinase 31 0.26
Hs4885403 [DK] KOG4152 Host cell transcription factor HCFC1 30 0.59
Hs14768289 [DK] KOG4152 Host cell transcription factor HCFC1 30 0.59
YLR337c [Z] KOG4462 WASP-interacting protein VRP1/WIP contains W... 29 1.0
7292338 [T] KOG2591 c-Mpl binding protein contains La domain 29 1.3
7302713 [S] KOG4790 Uncharacterized conserved protein 28 1.7
7299992 [Z] KOG1003 Actin filament-coating protein tropomyosin 28 1.7
7291158 [R] KOG1721 FOG: Zn-finger 28 2.2
Hs10047084 [K] KOG0527 HMG-box transcription factor 28 2.9
Hs4507127 [A] KOG3454 U1 snRNP-specific protein C 27 3.8
Hs20546752 [S] KOG4805 Uncharacterized conserved protein 27 3.8
At5g38560 [T] KOG1187 Serine/threonine protein kinase 27 3.8
Hs11968152_2 [T] KOG4375 Scaffold protein Shank and related SAM ... 27 3.8
Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 27 5.0
Hs4826874 [YU] KOG3630 Nuclear pore complex Nup214/CAN component 27 5.0
Hs4557681 [T] KOG0197 Tyrosine kinases 27 5.0
Hs21630255 [C] KOG0557 Dihydrolipoamide acetyltransferase 27 5.0
Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 27 5.0
Hs17458911 [C] KOG0557 Dihydrolipoamide acetyltransferase 27 5.0
At5g14600 [J] KOG2915 tRNA(1-methyladenosine) methyltransferase ... 27 5.0
CE22543 [KA] KOG2868 Decapping enzyme complex component DCP1 27 6.5
Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and... 27 6.5
Hs17484905_1 [R] KOG1311 DHHC-type Zn-finger proteins 27 6.5
HsM4827028 [B] KOG0639 Transducin-like enhancer of split protein... 26 8.5
Hs19923937 [R] KOG0383 Predicted helicase 26 8.5
Hs18497288 [T] KOG1217 Fibrillins and related proteins containin... 26 8.5
At4g32760 [U] KOG1087 Cytosolic sorting protein GGA2/TOM1 26 8.5
At4g29060 [J] KOG1071 Mitochondrial translation elongation facto... 26 8.5
7299344 [D] KOG4731 Protein predicted to be involved in spindle ... 26 8.5
>At4g32710 [T] KOG1187 Serine/threonine protein kinase
Length = 731
Score = 31.2 bits (69), Expect = 0.26
Identities = 19/53 (35%), Positives = 25/53 (46%), Gaps = 1/53 (1%)
Query: 19 ESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPPVP 71
ES P PI+SP P L PP L++ P P + + L F P+ P P
Sbjct: 69 ESPPSPPIESPPPPLLESPPPPPLESPSPPSPHVSAPSGSPPLP-FLPAKPSP 120
>Hs4885403 [DK] KOG4152 Host cell transcription factor HCFC1
Length = 1938
Score = 30.0 bits (66), Expect = 0.59
Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 5/62 (8%)
Query: 20 SQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPP-----VPTIS 74
S P P KSPAP A P Q +P+A A T P+ P VPT +
Sbjct: 320 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 379
Query: 75 KT 76
+T
Sbjct: 380 RT 381
>Hs14768289 [DK] KOG4152 Host cell transcription factor HCFC1
Length = 2035
Score = 30.0 bits (66), Expect = 0.59
Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 5/62 (8%)
Query: 20 SQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPP-----VPTIS 74
S P P KSPAP A P Q +P+A A T P+ P VPT +
Sbjct: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
Query: 75 KT 76
+T
Sbjct: 479 RT 480
>YLR337c [Z] KOG4462 WASP-interacting protein VRP1/WIP contains WH2 domain
Length = 817
Score = 29.3 bits (64), Expect = 1.0
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 20 SQPKTPIKSPAPELEVDAFPPCLQTFKP--GMPEATMAAEVDTLKVFWPSPPVPTISKTI 77
SQP P+ S AP + PP T P +P T A + T P PP+P +
Sbjct: 306 SQP--PLPSSAPPIPTSHAPPLPPTAPPPPSLPNVTSAPKKATSAPAPPPPPLPAAMSSA 363
Query: 78 SS 79
S+
Sbjct: 364 ST 365
>7292338 [T] KOG2591 c-Mpl binding protein contains La domain
Length = 1521
Score = 28.9 bits (63), Expect = 1.3
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 19 ESQPKTPIKSPAPELEVDAFPPCLQT--FKPGMPEATMAAEV 58
+ QP P++ P +LE AFPP T P P+AT A +
Sbjct: 1033 QQQPAAPVQPPQFDLEDAAFPPLPATSATAPHTPQATGGASL 1074
>7302713 [S] KOG4790 Uncharacterized conserved protein
Length = 649
Score = 28.5 bits (62), Expect = 1.7
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 20/70 (28%)
Query: 9 LGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSP 68
LG +D + + +S P+TP P P+ PP L KP E D P
Sbjct: 337 LGDLDTIEVLDSIPETPAPPPPPKTA----PPELPVLKP--------TEED--------P 376
Query: 69 PVPTISKTIS 78
P P + +T+S
Sbjct: 377 PTPDLRRTLS 386
>7299992 [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 566
Score = 28.5 bits (62), Expect = 1.7
Identities = 17/57 (29%), Positives = 22/57 (37%)
Query: 13 DAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPP 69
D + K P K P P E PP F+ + AEV +K + P PP
Sbjct: 390 DGAPAAPGEEKAPAKEPTPPKEPTPPPPPPPPFEYSIDLPPEGAEVPYVKNYEPPPP 446
>7291158 [R] KOG1721 FOG: Zn-finger
Length = 581
Score = 28.1 bits (61), Expect = 2.2
Identities = 18/55 (32%), Positives = 27/55 (48%), Gaps = 2/55 (3%)
Query: 8 ILGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQT--FKPGMPEATMAAEVDT 60
+LG V V +D + + PIK P E + PCLQ +P + E +E D+
Sbjct: 125 LLGSVLDVNVDSVEVREPIKEQLPCEEEEDEKPCLQASDSEPEVTEGQPESESDS 179
>Hs10047084 [K] KOG0527 HMG-box transcription factor
Length = 520
Score = 27.7 bits (60), Expect = 2.9
Identities = 11/31 (35%), Positives = 19/31 (60%)
Query: 1 MNEFSSQILGKVDAVTLDESQPKTPIKSPAP 31
++E SS+++G +DA + E P+ PAP
Sbjct: 340 ISELSSEVMGTMDAFDVHEFDQYLPLGGPAP 370
>Hs4507127 [A] KOG3454 U1 snRNP-specific protein C
Length = 159
Score = 27.3 bits (59), Expect = 3.8
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
Query: 1 MNEFSSQILGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQ-TFKPGMPEATMAAEVD 59
M E + ++ K A P TP +P P + PP L +PGM A
Sbjct: 42 MEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPP 101
Query: 60 TLKVFWPSPP 69
+ + P PP
Sbjct: 102 MMPMMGPPPP 111
>Hs20546752 [S] KOG4805 Uncharacterized conserved protein
Length = 1215
Score = 27.3 bits (59), Expect = 3.8
Identities = 17/64 (26%), Positives = 23/64 (35%)
Query: 10 GKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPP 69
G + L+E P TP +P P+ + PP Q P P P PP
Sbjct: 625 GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP 684
Query: 70 VPTI 73
P +
Sbjct: 685 PPAM 688
>At5g38560 [T] KOG1187 Serine/threonine protein kinase
Length = 681
Score = 27.3 bits (59), Expect = 3.8
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 2/53 (3%)
Query: 20 SQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPPVPT 72
S P T SP P + + + PP P P T++ PSPP PT
Sbjct: 79 SPPPTVASSPPPPVVIASPPPSTPATTPPAPPQTVSPPPPPDAS--PSPPAPT 129
>Hs11968152_2 [T] KOG4375 Scaffold protein Shank and related SAM domain proteins
Length = 1507
Score = 27.3 bits (59), Expect = 3.8
Identities = 17/60 (28%), Positives = 27/60 (44%), Gaps = 3/60 (5%)
Query: 17 LDESQPKTPIKS---PAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPPVPTI 73
L+ QP+ P+ S P E PP + P P + A+E + L + PP P++
Sbjct: 841 LENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSV 900
>Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related proteins
Length = 1188
Score = 26.9 bits (58), Expect = 5.0
Identities = 20/73 (27%), Positives = 27/73 (36%), Gaps = 11/73 (15%)
Query: 5 SSQILGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVF 64
SS G+ + +PKTP+ S AP P + KP E T
Sbjct: 1088 SSSAEGRAAGGDKSQGKPKTPVSSQAP-------VPAKRPIKPSRSEINQ----QTPPTP 1136
Query: 65 WPSPPVPTISKTI 77
P PP+P S +
Sbjct: 1137 TPRPPLPVKSPAV 1149
>Hs4826874 [YU] KOG3630 Nuclear pore complex Nup214/CAN component
Length = 2090
Score = 26.9 bits (58), Expect = 5.0
Identities = 18/61 (29%), Positives = 22/61 (35%)
Query: 20 SQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPPVPTISKTISS 79
S TP + P+ +A PP PG T AA V + P S T S
Sbjct: 1564 SAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSI 1623
Query: 80 V 80
V
Sbjct: 1624 V 1624
>Hs4557681 [T] KOG0197 Tyrosine kinases
Length = 1124
Score = 26.9 bits (58), Expect = 5.0
Identities = 12/43 (27%), Positives = 24/43 (54%)
Query: 36 DAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPPVPTISKTIS 78
D PP ++ PG+ A ++ E+ T ++ W +P ++T+S
Sbjct: 661 DGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLS 703
>Hs21630255 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 613
Score = 26.9 bits (58), Expect = 5.0
Identities = 14/33 (42%), Positives = 15/33 (45%)
Query: 16 TLDESQPKTPIKSPAPELEVDAFPPCLQTFKPG 48
TLD S TP +PAP A PP PG
Sbjct: 147 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPG 179
>Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 799
Score = 26.9 bits (58), Expect = 5.0
Identities = 20/73 (27%), Positives = 27/73 (36%), Gaps = 11/73 (15%)
Query: 5 SSQILGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVF 64
SS G+ + +PKTP+ S AP P + KP E T
Sbjct: 699 SSSAEGRAAGGDKSQGKPKTPVSSQAP-------VPAKRPIKPSRSEINQ----QTPPTP 747
Query: 65 WPSPPVPTISKTI 77
P PP+P S +
Sbjct: 748 TPRPPLPVKSPAV 760
>Hs17458911 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 647
Score = 26.9 bits (58), Expect = 5.0
Identities = 14/33 (42%), Positives = 15/33 (45%)
Query: 16 TLDESQPKTPIKSPAPELEVDAFPPCLQTFKPG 48
TLD S TP +PAP A PP PG
Sbjct: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPG 212
>At5g14600 [J] KOG2915 tRNA(1-methyladenosine) methyltransferase subunit GCD14
Length = 370
Score = 26.9 bits (58), Expect = 5.0
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 4 FSSQILGKVDAVTLDESQPKTPIKSPAPELEVD----AFPPCLQ 43
F ++ G D+V LD QP + S A L+ D +F PC++
Sbjct: 174 FPEKLSGLADSVFLDLPQPWLAVPSAAKMLKQDGVLCSFSPCIE 217
>CE22543 [KA] KOG2868 Decapping enzyme complex component DCP1
Length = 332
Score = 26.6 bits (57), Expect = 6.5
Identities = 18/55 (32%), Positives = 26/55 (46%), Gaps = 3/55 (5%)
Query: 3 EFSSQILGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAE 57
+ + Q KVD + L +S P KS A ++ PP LQ P A M+A+
Sbjct: 170 QMAPQAPPKVDLLQLIKSAQNPPQKSAA---TIEQMPPMLQKLMLKEPGAAMSAD 221
>Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1139
Score = 26.6 bits (57), Expect = 6.5
Identities = 11/47 (23%), Positives = 25/47 (52%), Gaps = 1/47 (2%)
Query: 35 VDAFPPCLQTFKPGMP-EATMAAEVDTLKVFWPSPPVPTISKTISSV 80
++ + CL+ +K +A + ++ LKV W S +PT+ ++ +
Sbjct: 767 IEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADI 813
>Hs17484905_1 [R] KOG1311 DHHC-type Zn-finger proteins
Length = 578
Score = 26.6 bits (57), Expect = 6.5
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 13/67 (19%)
Query: 9 LGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSP 68
L ++D LD P P ++E F LQT +PG E+ L V SP
Sbjct: 211 LDRLDEKPLDLGPPLPP------KIEAGTFSSDLQTPRPGSAES-------ALSVQRTSP 257
Query: 69 PVPTISK 75
P P + K
Sbjct: 258 PTPAMYK 264
>HsM4827028 [B] KOG0639 Transducin-like enhancer of split protein (contains
WD40 repeats)
Length = 770
Score = 26.2 bits (56), Expect = 8.5
Identities = 15/49 (30%), Positives = 17/49 (34%)
Query: 29 PAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSPPVPTISKTI 77
P P + V PP L G P + D P PP P I I
Sbjct: 423 PPPHMRVPTIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPTPLIGPGI 471
>Hs19923937 [R] KOG0383 Predicted helicase
Length = 531
Score = 26.2 bits (56), Expect = 8.5
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 9/76 (11%)
Query: 5 SSQILGKVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVF 64
S Q L A L + +PKT I P PP P A V ++K
Sbjct: 57 SLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPP-------KQPPTFQKATVVSVKN- 108
Query: 65 WPSPPVPTISKTISSV 80
PSP +PT + T+S V
Sbjct: 109 -PSPALPTANNTVSHV 123
>Hs18497288 [T] KOG1217 Fibrillins and related proteins containing Ca2+-binding
EGF-like domains
Length = 1256
Score = 26.2 bits (56), Expect = 8.5
Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 24 TPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKV 63
TP + P PEL PP ++ F P +P + A E+ +V
Sbjct: 534 TPAR-PYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQV 572
>At4g32760 [U] KOG1087 Cytosolic sorting protein GGA2/TOM1
Length = 838
Score = 26.2 bits (56), Expect = 8.5
Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 11 KVDAVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPG--MPEATMAAEVDTLKV 63
+ AV S+ P+ +P + ++PP L+ PG +PE + E TL +
Sbjct: 165 RAGAVFPQRSERSAPVFTPPQTQPLTSYPPNLRNAGPGNDVPEPSAEPEFPTLSL 219
>At4g29060 [J] KOG1071 Mitochondrial translation elongation factor EF-Tsmt
catalyzes nucleotide exchange on EF-Tumt
Length = 953
Score = 26.2 bits (56), Expect = 8.5
Identities = 18/71 (25%), Positives = 30/71 (41%), Gaps = 6/71 (8%)
Query: 14 AVTLDESQPKTPIKSPAPELEVDAFPPCLQTFKPGMPEATMAAEVDTLKVFWPSP----- 68
A +E P P E+ ++ PP T + PEA + EV+ +V +P
Sbjct: 434 AAEAEEVVPPIPETKSEEEIVENSIPPNSATDEVSSPEALASEEVEKEQVVAETPVDEVK 493
Query: 69 -PVPTISKTIS 78
P P +++ S
Sbjct: 494 TPAPVVTEASS 504
>7299344 [D] KOG4731 Protein predicted to be involved in spindle matrix
formation contains DM13 DoH and DOMON domains
Length = 1233
Score = 26.2 bits (56), Expect = 8.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 11 KVDAVTLDESQPKTPIKSPAPELEVDAFPP 40
K DAVT + P+ K P P+L D F P
Sbjct: 1021 KKDAVTTTINIPRNTTKKPDPDLLEDLFGP 1050
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.129 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,198,343
Number of Sequences: 60738
Number of extensions: 205610
Number of successful extensions: 532
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 512
Number of HSP's gapped (non-prelim): 37
length of query: 80
length of database: 30,389,216
effective HSP length: 56
effective length of query: 24
effective length of database: 26,987,888
effective search space: 647709312
effective search space used: 647709312
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)