ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5620 good R KOG1577 General function prediction only Aldo/keto reductase family proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5620 1930283 1929297 -329
(329 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR104w [R] KOG1577 Aldo/keto reductase family proteins 477 e-135
Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins 230 2e-60
7294702 [R] KOG1577 Aldo/keto reductase family proteins 229 4e-60
Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins 226 4e-59
Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins 222 7e-58
At2g21250 [R] KOG1577 Aldo/keto reductase family proteins 219 6e-57
7294701 [R] KOG1577 Aldo/keto reductase family proteins 216 4e-56
ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins 215 8e-56
Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins 213 3e-55
At2g21260 [R] KOG1577 Aldo/keto reductase family proteins 213 3e-55
Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins 211 9e-55
CE21733 [R] KOG1577 Aldo/keto reductase family proteins 208 1e-53
SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins 207 2e-53
Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins 207 2e-53
CE24243 [R] KOG1577 Aldo/keto reductase family proteins 207 2e-53
7298972 [R] KOG1577 Aldo/keto reductase family proteins 201 1e-51
At2g37760 [R] KOG1577 Aldo/keto reductase family proteins 198 1e-50
Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins 197 1e-50
Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins 197 2e-50
At2g37790 [R] KOG1577 Aldo/keto reductase family proteins 196 4e-50
7292407 [R] KOG1577 Aldo/keto reductase family proteins 196 5e-50
SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins 194 2e-49
At2g37770 [R] KOG1577 Aldo/keto reductase family proteins 194 2e-49
7302301 [R] KOG1577 Aldo/keto reductase family proteins 187 2e-47
7294572 [R] KOG1577 Aldo/keto reductase family proteins 186 3e-47
7292408 [R] KOG1577 Aldo/keto reductase family proteins 186 3e-47
Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins 186 5e-47
Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins 185 7e-47
CE24244 [R] KOG1577 Aldo/keto reductase family proteins 185 7e-47
Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins 182 4e-46
At3g53880 [R] KOG1577 Aldo/keto reductase family proteins 181 1e-45
CE17230 [R] KOG1577 Aldo/keto reductase family proteins 181 1e-45
At5g62420 [R] KOG1577 Aldo/keto reductase family proteins 179 5e-45
YDR368w [R] KOG1577 Aldo/keto reductase family proteins 166 4e-41
YOR120w [R] KOG1577 Aldo/keto reductase family proteins 163 4e-40
7294573 [R] KOG1577 Aldo/keto reductase family proteins 160 2e-39
CE10936 [R] KOG1577 Aldo/keto reductase family proteins 157 3e-38
Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins 154 2e-37
CE06776 [R] KOG1577 Aldo/keto reductase family proteins 154 2e-37
At5g01670 [R] KOG1577 Aldo/keto reductase family proteins 154 2e-37
At1g59960 [R] KOG1577 Aldo/keto reductase family proteins 153 4e-37
At1g59950 [R] KOG1577 Aldo/keto reductase family proteins 152 6e-37
Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins 151 1e-36
Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins 149 4e-36
CE27788 [R] KOG1577 Aldo/keto reductase family proteins 146 4e-35
YJR096w [R] KOG1577 Aldo/keto reductase family proteins 143 4e-34
YBR149w [R] KOG1577 Aldo/keto reductase family proteins 142 7e-34
CE10934 [R] KOG1577 Aldo/keto reductase family proteins 141 1e-33
SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins 139 7e-33
CE01200 [R] KOG1577 Aldo/keto reductase family proteins 137 2e-32
CE06751 [R] KOG1577 Aldo/keto reductase family proteins 131 1e-30
CE06112 [R] KOG1577 Aldo/keto reductase family proteins 131 2e-30
SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins 124 2e-28
Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins 123 3e-28
SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins 122 7e-28
YDL124w [R] KOG1577 Aldo/keto reductase family proteins 107 2e-23
Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins 93 6e-19
CE15543 [R] KOG1577 Aldo/keto reductase family proteins 92 1e-18
SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins 84 3e-16
At1g60680 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 77 3e-14
CE06775 [R] KOG1577 Aldo/keto reductase family proteins 69 1e-11
Hs22048214 [R] KOG1577 Aldo/keto reductase family proteins 67 5e-11
Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins 65 1e-10
Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins 65 1e-10
At1g60690 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 65 1e-10
At1g60750 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 65 2e-10
At1g60730 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 62 9e-10
At1g10810 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 57 4e-08
At1g04690 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 51 2e-06
Hs17491434 [R] KOG1577 Aldo/keto reductase family proteins 51 3e-06
>YHR104w [R] KOG1577 Aldo/keto reductase family proteins
Length = 327
Score = 477 bits (1228), Expect = e-135
Identities = 227/326 (69%), Positives = 269/326 (81%), Gaps = 1/326 (0%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
++ VTLNNG KMPLVGLGCWK+ VCA+QIYEAIK+GYRLFDGA DY NEKEVG+G+
Sbjct: 1 MSSLVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIR 60
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
+AI EGLV R+D+ VVSKLWN+FHHPD+V AL++TLSD+ LDY+D++YIHFP+AFK VP
Sbjct: 61 KAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVP 120
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
F+EKYPPGFYTG +DE KGHI E VP++DT+RALE+ VD+G IKS+G+SNF G+LIQDL
Sbjct: 121 FEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDL 180
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTL 243
LRG RIKPVALQIEHHPYLTQE L+++ K IQVVAYSSFGP SF+E++ + A TPTL
Sbjct: 181 LRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTL 240
Query: 244 FEHDTIKSIASKHK-VTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
FE+D IK ++ H T QVLLRWATQ GIA+IPKSSKKERLL NL I TLT+ EL
Sbjct: 241 FENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQEL 300
Query: 303 KQISGLNQNIRFNDPWEWLDNEFPTF 328
K IS LN NIRFNDPW WLD +FPTF
Sbjct: 301 KDISALNANIRFNDPWTWLDGKFPTF 326
>Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 230 bits (586), Expect = 2e-60
Identities = 127/316 (40%), Positives = 183/316 (57%), Gaps = 25/316 (7%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+A + LNNG KMP++GLG WK P + + AI +GYR D A Y NE EVG +
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKP-- 121
++E +VKRE+L +VSKLW ++H V A ++TLSDL+LDY+D++ IH+P FKP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 122 --VPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGAL 179
P DE G++ +LDTW A+E+LVD+G +K++GISNF+
Sbjct: 121 EFFPLDE--------------SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQ 166
Query: 180 IQDLLR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKA 237
++ +L G + KP QIE HPYLTQE+LI+Y ++ GI V AYS G
Sbjct: 167 VEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD----RPWAK 222
Query: 238 LNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTL 297
P+L E IK+IA+KH T QVL+R+ Q + +IPKS ER+ +N ++ D L
Sbjct: 223 PEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFD-FEL 281
Query: 298 TDDELKQISGLNQNIR 313
+ ++ + N+N R
Sbjct: 282 SSQDMTTLLSYNRNWR 297
>7294702 [R] KOG1577 Aldo/keto reductase family proteins
Length = 302
Score = 229 bits (584), Expect = 4e-60
Identities = 130/306 (42%), Positives = 179/306 (58%), Gaps = 15/306 (4%)
Query: 8 VTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIK 67
V NNG+++P++GLG W P + + AI GYR D A Y NE EVG GV IK
Sbjct: 6 VKFNNGKEVPIIGLGTWGSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIK 65
Query: 68 EGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEK 127
EG+VKREDL + SKLWN+FH PD V ALE TLS L+L Y+D++ IH+P+ +K +
Sbjct: 66 EGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYK------E 119
Query: 128 YPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGA 187
F T K+ G V +DTW+A+EKLV++G +KS+G+SNF+ I+ +L A
Sbjct: 120 GCDLFPTDKD----GKTLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVA 175
Query: 188 RIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHD 247
I PV QIE HPYLTQ++LI + K+ I + AYS G + P + E
Sbjct: 176 TIPPVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSPN----RPWAKAGDPVILEEA 231
Query: 248 TIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISG 307
IK IA+K K TP Q+L+R+ Q +IPKS K+R+ N ++ D LT +E++ I
Sbjct: 232 KIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFD-FELTPEEIEIIES 290
Query: 308 LNQNIR 313
N R
Sbjct: 291 FECNGR 296
>Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 226 bits (576), Expect = 4e-59
Identities = 133/312 (42%), Positives = 183/312 (58%), Gaps = 17/312 (5%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+A V L+ KMP+VGLG WK P + + AI GYR D A Y NE EVG+ +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
I+E VKREDL +VSKLW +F V +A E+TL DL+L Y+D++ IH+P FK
Sbjct: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--S 118
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
D+ +P K+D KG+ + LD W A+E+LVD+G +K+LG+SNFS I+ L
Sbjct: 119 GDDLFP------KDD--KGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKL 170
Query: 184 LR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTP 241
L G + KPV Q+E HPYLTQE+LI+Y + GI V AYS G P
Sbjct: 171 LNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD----RPWAKPEDP 226
Query: 242 TLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDE 301
+L E IK IA+KHK T QVL+R+ Q + +IPKS R+++N+++ D L+D+E
Sbjct: 227 SLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFD-FKLSDEE 285
Query: 302 LKQISGLNQNIR 313
+ I N+N R
Sbjct: 286 MATILSFNRNWR 297
>Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 222 bits (565), Expect = 7e-58
Identities = 122/321 (38%), Positives = 185/321 (57%), Gaps = 16/321 (4%)
Query: 5 AETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNR 64
A V L+ G+KMPL+GLG WK + A+ +GYR D A Y NE E+G+ +
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62
Query: 65 AIKEG-LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
+ G V RE+L V SKLWN+ HHP++V AL +TL+DLQL+Y+D++ +H+P AF+
Sbjct: 63 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG- 121
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
D +P A G I + +TW+ALE LV +G +++LG+SNF+ I D+
Sbjct: 122 -DNPFPKN--------ADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDI 172
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTL 243
L A ++P LQ+E HPYL Q LI + + G++V AYS G + + P L
Sbjct: 173 LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSD----RAWRDPDEPVL 228
Query: 244 FEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELK 303
E + ++A K+ +P Q+LLRW Q + IPKS R+L N+++ D T + +E+K
Sbjct: 229 LEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFD-FTFSPEEMK 287
Query: 304 QISGLNQNIRFNDPWEWLDNE 324
Q++ LN+N R+ P +D +
Sbjct: 288 QLNALNKNWRYIVPMLTVDGK 308
>At2g21250 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 219 bits (557), Expect = 6e-57
Identities = 125/314 (39%), Positives = 177/314 (55%), Gaps = 21/314 (6%)
Query: 8 VTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIK 67
+TLN+G KMP+VGLG W+M + D I AIKIGYR D A DY NE EVG + A K
Sbjct: 3 ITLNSGFKMPIVGLGVWRMEKEGIRDLILNAIKIGYRHLDCAADYRNETEVGDALTEAFK 62
Query: 68 EGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEK 127
GLVKREDL + +KLWNS H +V A + +L LQLDY+D+F +HFP+A K
Sbjct: 63 TGLVKREDLFITTKLWNSDH--GHVIEACKDSLKKLQLDYLDLFLVHFPVATKHTG---- 116
Query: 128 YPPGFYTGKEDEAKGHIE----EEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
G D A G + + L TW +EKLV G ++S+GISN+ L +D
Sbjct: 117 ------VGTTDSALGDDGVLDIDTTISLETTWHDMEKLVSMGLVRSIGISNYDVFLTRDC 170
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTL 243
L ++IKP QIE HPY ++ L+K+ + GI V A++ G + N + T +
Sbjct: 171 LAYSKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGAT----ANAEWFGTVSC 226
Query: 244 FEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELK 303
+ +K +A K+K T QV+LRW Q +IPK+SK RL +N ++ D L+ ++++
Sbjct: 227 LDDPVLKDVAEKYKKTVAQVVLRWGIQRKTVVIPKTSKPARLEENFQVFD-FELSKEDME 285
Query: 304 QISGLNQNIRFNDP 317
I + + R N P
Sbjct: 286 VIKSMERKYRTNQP 299
>7294701 [R] KOG1577 Aldo/keto reductase family proteins
Length = 305
Score = 216 bits (550), Expect = 4e-56
Identities = 123/305 (40%), Positives = 182/305 (59%), Gaps = 12/305 (3%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
L+NG+ MP++GLG W+ P +V + +AI IGYR FD A Y NE +VG + + EG
Sbjct: 8 LSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEG 67
Query: 70 LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYP 129
+V R++L + SKLWN+ H PD V A E ++ +L + Y++++ +H+P+A+K D YP
Sbjct: 68 VVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKS-GSDNLYP 126
Query: 130 PGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARI 189
T K E + +DTWRA+E LVD+G +++G+SNF+ + LL A++
Sbjct: 127 TCPDTNK-------AAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKL 179
Query: 190 KPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTI 249
KPV LQIE HPYL+Q+ LI + I V AYS G E A L +H TI
Sbjct: 180 KPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGS-GHTPYEKPGAY---PLLQHPTI 235
Query: 250 KSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGLN 309
+IA K++ T QVLLR+ TQ+GI +IP+S K+ +LDN + L D+++ I+ L+
Sbjct: 236 LAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELD 295
Query: 310 QNIRF 314
N RF
Sbjct: 296 CNGRF 300
>ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 215 bits (547), Expect = 8e-56
Identities = 127/320 (39%), Positives = 185/320 (57%), Gaps = 35/320 (10%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPND-VCADQIYEAIKIGYRLFDGAQDYANEKEVGQGV 62
+ +T LNNG+++P VGLG W M ++ V I A+ +GYR D A Y NEK +G +
Sbjct: 2 ICKTQKLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNIL 61
Query: 63 NRAIKEGLVKREDLVVVSKLWNSFHH-PDNVPRALERTLSDLQLDYVDIFYIHFPLAFKP 121
+ EG+V+R+DL + SKLWN+FH P++ L R+L+DLQ+DYVD++ IH+P+ F P
Sbjct: 62 KKLFDEGVVQRKDLFITSKLWNTFHGCPED---GLRRSLNDLQMDYVDLYLIHWPVTFDP 118
Query: 122 VPFD--EKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGAL 179
P E + GK D + W+ +E LVD G KS+GISNF A
Sbjct: 119 APDGTVESCGKKYNVGKFDA------------VGVWKKMEALVDLGLAKSIGISNFGKAN 166
Query: 180 IQDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFG--PVSFLELENKKA 237
+ +L RI P A+QIE HPYL Q+ L++++K+ GIQV++YSS G P S ++ + K
Sbjct: 167 TEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAKVRDDK- 225
Query: 238 LNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTL 297
TIK+IA K+ P Q++L + T GI +IPKS KE L +N+ D L
Sbjct: 226 ----------TIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEHLRENI---DLKEL 272
Query: 298 TDDELKQISGLNQNIRFNDP 317
+ +++ I LN R+ DP
Sbjct: 273 SREDISAIDALNTGHRYVDP 292
>Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 213 bits (542), Expect = 3e-55
Identities = 125/326 (38%), Positives = 186/326 (56%), Gaps = 21/326 (6%)
Query: 8 VTLNNGEKMPLVGLGCWKMPNDV----CADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+ L++G +P++GLG + P CA + AI GYR DGA Y NE EVG+ +
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
I EG V+RED+ KLW + H P+ V LERTL LQLDYVD++ I P+AFK P
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK--P 127
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
DE YP +++ K + L TW A+E D G +KSLG+SNF+ ++ +
Sbjct: 128 GDEIYP------RDENGKWLYHKSN--LCATWEAMEACKDAGLVKSLGVSNFNRRQLELI 179
Query: 184 LR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTP 241
L G + KPV+ Q+E HPY TQ +L+K+ + I + AYS G N +++P
Sbjct: 180 LNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVN---VSSP 236
Query: 242 TLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDE 301
L + + S+ ++ T Q++LR+ Q G+ +IPKS ER+ +N +I D +LT++E
Sbjct: 237 PLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFD-FSLTEEE 295
Query: 302 LKQISGLNQNIRFNDPWEWLDN-EFP 326
+K I LN+N+RF + W D+ E+P
Sbjct: 296 MKDIEALNKNVRFVELLMWRDHPEYP 321
>At2g21260 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 213 bits (542), Expect = 3e-55
Identities = 119/310 (38%), Positives = 177/310 (56%), Gaps = 21/310 (6%)
Query: 8 VTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIK 67
+TLN+G KMP++GLG W+M + D I +AIKIGYR D A +Y NE EVG+ + A
Sbjct: 3 ITLNSGFKMPIIGLGVWRMEKEELRDLIIDAIKIGYRHLDCAANYKNEAEVGEALTEAFT 62
Query: 68 EGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEK 127
GLVKREDL + +KLW+S H +V A + +L LQLDY+D+F +H P+A K
Sbjct: 63 TGLVKREDLFITTKLWSSDH--GHVIEACKDSLKKLQLDYLDLFLVHIPIATKHTGI--- 117
Query: 128 YPPGFYTGKEDEAKGHIE----EEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
G D A G + + L TW +EKLV G ++S+GISN+ L +D
Sbjct: 118 -------GTTDSALGDDGVLDIDTTISLETTWHDMEKLVSMGLVRSIGISNYDVFLTRDC 170
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTL 243
L ++IKP QIE HPY ++ L+K+ + GI V A++ G + N + T +
Sbjct: 171 LAYSKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGAT----ANAEWFGTVSC 226
Query: 244 FEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELK 303
+ +K +A K+K T Q++LRW Q +IPK+SK ERL +N ++ D L+ ++++
Sbjct: 227 LDDPVLKDVAEKYKQTVAQIVLRWGIQRNTVVIPKTSKPERLEENFQVFD-FQLSKEDME 285
Query: 304 QISGLNQNIR 313
I + +N R
Sbjct: 286 VIKSMERNYR 295
>Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 211 bits (538), Expect = 9e-55
Identities = 122/318 (38%), Positives = 185/318 (57%), Gaps = 27/318 (8%)
Query: 6 ETVTLNNGEKMPLVGLGCW---KMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGV 62
+ V LN+G MP++G G + ++P + + AI+ G+ D A Y NE++VG +
Sbjct: 6 QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 63 NRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKP- 121
I +G VKRED+ SKLW++ H P+ V ALER+L +LQLDYVD++ IHFP++ KP
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 122 ---VPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGA 178
+P DE G I + V L TW A+EK D G KS+G+SNF+
Sbjct: 126 EEVIPKDE--------------NGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHR 171
Query: 179 LIQDLLR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKK 236
L++ +L G + KPV Q+E HPY Q +L+ + K+ I +VAYS+ G S E E
Sbjct: 172 LLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG--SHRE-EPWV 228
Query: 237 ALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALT 296
N+P L E + ++A KHK TP + LR+ Q G+ ++ KS ++R+ N+++ +
Sbjct: 229 DPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE-FQ 287
Query: 297 LTDDELKQISGLNQNIRF 314
LT +E+K I GLN+N+R+
Sbjct: 288 LTSEEMKAIDGLNRNVRY 305
>CE21733 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 208 bits (529), Expect = 1e-53
Identities = 116/314 (36%), Positives = 173/314 (54%), Gaps = 16/314 (5%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+ +++ LN+G +P +GLG W+ A I A+ GYR D A Y N+KEVG+ +
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALK 60
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
+ EG VKRE+L + SK+WN+FH ++ LSDLQL YVD+ IH+P +
Sbjct: 61 EILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGY--AE 118
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
E +P G G + V L+TW+A E GK +S+G+SNF+ + IQ +
Sbjct: 119 GAELFPAG--------ENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRV 170
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFG-PVSFLELENKKALNTPT 242
A +KP LQ+E HPY TQ +L ++ K GI VV YS G P S ++ P
Sbjct: 171 WDAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKD----GDPN 226
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
+ ++ + IA H TP Q++LRW +G++ IPKS +R+ +NL + D LT +E+
Sbjct: 227 VLTNEVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISENLAVFD-FQLTAEEI 285
Query: 303 KQISGLNQNIRFND 316
+I G+N+N R D
Sbjct: 286 SKIDGINKNWRIVD 299
>SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins
Length = 321
Score = 207 bits (527), Expect = 2e-53
Identities = 116/309 (37%), Positives = 185/309 (59%), Gaps = 24/309 (7%)
Query: 9 TLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKE 68
TL +G K+P +GLG W+ + + + A++ GYR D A Y NE EVG G IKE
Sbjct: 17 TLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDG----IKE 72
Query: 69 GLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKY 128
V R+D+ V SKLW + H P+ VP+ALE+TL DL+LDY+D + IH+P++FK ++K+
Sbjct: 73 SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTG--EDKF 130
Query: 129 PPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGAR 188
P + G++ E+ P+ +TW+A+EKL++ GK++ +G+SNF+ ++ +L+ A+
Sbjct: 131 PK--------DKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAK 182
Query: 189 IKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDT 248
+KP Q+E HP+L Q ++ K GI V AYS FG + + E+K P L EH+T
Sbjct: 183 VKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTI-YESK----IPKLIEHET 237
Query: 249 IKSIASK--HKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQIS 306
I+ IA VT + + WA G ++IPKS ++R+ N + + LT +++ +I+
Sbjct: 238 IQKIAKSKGEGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFKY---IPLTKEDMDEIN 294
Query: 307 GLNQNIRFN 315
+ RFN
Sbjct: 295 SIGIRARFN 303
>Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 207 bits (527), Expect = 2e-53
Identities = 122/318 (38%), Positives = 183/318 (57%), Gaps = 27/318 (8%)
Query: 6 ETVTLNNGEKMPLVGLGCW---KMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGV 62
+ V LN+G MP++G G + ++P + AI+ G+R D A Y NE++VG +
Sbjct: 6 QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 63 NRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKP- 121
I +G VKRED+ SKLW + H P+ V ALER+L +LQLDYVD++ IHFP++ KP
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 122 ---VPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGA 178
+P DE G I + V L TW A+EK D G KS+G+SNF+
Sbjct: 126 EEVIPKDE--------------NGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRR 171
Query: 179 LIQDLLR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKK 236
++ +L G + KPV Q+E HPY Q +L+ + K+ I +VAYS+ G S E E
Sbjct: 172 QLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG--SHRE-EPWV 228
Query: 237 ALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALT 296
N+P L E + ++A KHK TP + LR+ Q G+ ++ KS ++R+ N+++ +
Sbjct: 229 DPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE-FQ 287
Query: 297 LTDDELKQISGLNQNIRF 314
LT +E+K I GLN+N+R+
Sbjct: 288 LTSEEMKAIDGLNRNVRY 305
>CE24243 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 207 bits (526), Expect = 2e-53
Identities = 114/315 (36%), Positives = 174/315 (55%), Gaps = 16/315 (5%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+ +++ LN+G +P +GLG W+ A I A+ GYR D A Y N+KEVG+ +
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALK 60
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
+ EG VKRE+L + SK+WN+FH ++ LSDLQL YVD+ IH+P +
Sbjct: 61 EILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGY--AE 118
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
E +P G G + V L+TW+A E GK +S+G+SNF+ + IQ +
Sbjct: 119 GAELFPAG--------ENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRV 170
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFG-PVSFLELENKKALNTPT 242
A +KP LQ+E HPY TQ +L ++ K GI VV YS G P S ++ P
Sbjct: 171 WDAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKD----GDPN 226
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
+ ++ + IA H TP Q++LRW +G++ IPKS +R+++N+ + D L+ +E+
Sbjct: 227 VLTNEVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRIIENISVID-FQLSAEEI 285
Query: 303 KQISGLNQNIRFNDP 317
+ I G+N+ R DP
Sbjct: 286 QAIDGVNRGWRLVDP 300
>7298972 [R] KOG1577 Aldo/keto reductase family proteins
Length = 329
Score = 201 bits (511), Expect = 1e-51
Identities = 115/311 (36%), Positives = 171/311 (54%), Gaps = 11/311 (3%)
Query: 8 VTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIK 67
+T NNGEKMP++G+G W+ ++ I A++ GYR D A Y NEK +G+ + R +
Sbjct: 7 LTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66
Query: 68 EGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEK 127
G VKRE+L +V+K+ + P V ++++L DLQLDYVD++ +H P +
Sbjct: 67 AGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT-----ININ 121
Query: 128 YPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGA 187
F KE + + + W A+E LV++G KS+G+SNFS + LL+
Sbjct: 122 EDGSFKLDKEGLMEVDVTTNHAAI---WVAMEALVEKGLTKSIGVSNFSKDQVARLLKNC 178
Query: 188 RIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKAL--NTPTLFE 245
+I+P QIEHH YL Q L+ + K+ I V AYS G + + + P L +
Sbjct: 179 KIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMD 238
Query: 246 HDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQI 305
+K IA+ H TP QVLLRW G++ IPKS+ RL NL + D LT +E+ ++
Sbjct: 239 IPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFD-FELTAEEVAKL 297
Query: 306 SGLNQNIRFND 316
S L+QNIR D
Sbjct: 298 SSLDQNIRICD 308
>At2g37760 [R] KOG1577 Aldo/keto reductase family proteins
Length = 294
Score = 198 bits (503), Expect = 1e-50
Identities = 117/305 (38%), Positives = 169/305 (55%), Gaps = 27/305 (8%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
LN G K+P VGLG + M A I +AIKIGYR D A Y NEKE+G + + I +G
Sbjct: 10 LNTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65
Query: 70 LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYP 129
VKRE+L + SKLW++ H P++VP+ALE+TL DLQ+DYVD++ IH+P + K + P
Sbjct: 66 FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK---ESLMP 122
Query: 130 PGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARI 189
K D + TW+A+E L D GK +++G+SNFS + DLL AR+
Sbjct: 123 TPEMLTKPD------------ITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARV 170
Query: 190 KPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTI 249
P Q+E HP Q+ L + K+ G+ + YS G S E+ K + ++ +
Sbjct: 171 TPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK-------VLQNPIV 223
Query: 250 KSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGLN 309
+A K T QV LRW Q G +++PKSS RL +NL + D ++ +D + S +
Sbjct: 224 TEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFD-WSIPEDLFTKFSNIP 282
Query: 310 QNIRF 314
Q F
Sbjct: 283 QASSF 287
>Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 197 bits (502), Expect = 1e-50
Identities = 114/318 (35%), Positives = 179/318 (55%), Gaps = 27/318 (8%)
Query: 6 ETVTLNNGEKMPLVGLGCW---KMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGV 62
+ V LN+G MP++G G + ++P + + AI+ G+R D A Y NE++VG +
Sbjct: 6 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 63 NRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFK-- 120
I +G VKRED+ SKLW +F P V ALE +L LQLDYVD++ +HFP+A K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
Query: 121 --PVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGA 178
P+P DE G + + V L TW +EK D G KS+G+SNF+
Sbjct: 126 ETPLPKDE--------------NGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCR 171
Query: 179 LIQDLLR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKK 236
++ +L G + KPV Q+E HPYL Q +L+ + K+ I +VA+S+ G +
Sbjct: 172 QLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDP- 230
Query: 237 ALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALT 296
N+P L E + ++A KHK TP + LR+ Q G+ ++ KS ++R+ +N+++ +
Sbjct: 231 --NSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFE-FQ 287
Query: 297 LTDDELKQISGLNQNIRF 314
LT +++K + GLN+N R+
Sbjct: 288 LTSEDMKVLDGLNRNYRY 305
>Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 197 bits (500), Expect = 2e-50
Identities = 112/316 (35%), Positives = 181/316 (56%), Gaps = 23/316 (7%)
Query: 6 ETVTLNNGEKMPLVGLGCW---KMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGV 62
+ V LN+G MP++G G + ++P + AI+ G+R D A Y NE++VG +
Sbjct: 6 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 63 NRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPV 122
I +G VKRED+ SKLW++FH P+ V ALE +L QLDYVD++ IH P++ KP
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP- 124
Query: 123 PFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQD 182
E+ P + G + + V L TW A+EK D G KS+G+SNF+ ++
Sbjct: 125 --GEELSP-------TDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEM 175
Query: 183 LLR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKAL-- 238
+L G + KPV Q+E HPY + +L+ + K+ I +VAYS+ G +K+ +
Sbjct: 176 ILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG-----SQRDKRWVDP 230
Query: 239 NTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLT 298
N+P L E + ++A KHK TP + LR+ Q G+ ++ KS ++R+ N+++ + LT
Sbjct: 231 NSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE-FQLT 289
Query: 299 DDELKQISGLNQNIRF 314
+++K I GL++N+ +
Sbjct: 290 AEDMKAIDGLDRNLHY 305
>At2g37790 [R] KOG1577 Aldo/keto reductase family proteins
Length = 350
Score = 196 bits (498), Expect = 4e-50
Identities = 112/301 (37%), Positives = 166/301 (54%), Gaps = 23/301 (7%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
LN G K+P VGLG W+ + + + A+KIGYR D AQ Y NEKE+G + + G
Sbjct: 10 LNTGAKIPSVGLGTWQADPGLVGNAVDAAVKIGYRHIDCAQIYGNEKEIGLVLKKLFDGG 69
Query: 70 LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYP 129
+VKRE++ + SKLW ++H P VP AL RTL DLQLDYVD++ IH+P++ K K
Sbjct: 70 VVKREEMFITSKLWCTYHDPQEVPEALNRTLQDLQLDYVDLYLIHWPVSLK------KGS 123
Query: 130 PGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARI 189
GF +I +P TW+A+E L D GK +++G+SNFS + DLL AR+
Sbjct: 124 TGF-------KPENILPTDIP--STWKAMESLFDSGKARAIGVSNFSSKKLADLLVVARV 174
Query: 190 KPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTI 249
P Q+E HP Q L + K+ G+ + YS G L T + ++ +
Sbjct: 175 PPAVNQVECHPSWQQNVLRDFCKSKGVHLSGYSPLGSPGTTWL-------TSDVLKNPIL 227
Query: 250 KSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGLN 309
+A K TP QV LRW Q G +++PKS+ ++R+ N + + ++ +D L + S +
Sbjct: 228 GGVAEKLGKTPAQVALRWGLQMGQSVLPKSTHEDRIKQNFDVFN-WSIPEDMLSKFSEIG 286
Query: 310 Q 310
Q
Sbjct: 287 Q 287
>7292407 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 196 bits (497), Expect = 5e-50
Identities = 107/283 (37%), Positives = 158/283 (55%), Gaps = 15/283 (5%)
Query: 11 NNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGL 70
N+G + +GLG + C + AI +GYR D A Y NE EVG V + I EG+
Sbjct: 12 NDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGV 71
Query: 71 VKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPP 130
+KRED+ + +KLW +FH P+ V A +TL ++ LDYVD++ IH+P ++K +E P
Sbjct: 72 IKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIP- 130
Query: 131 GFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIK 190
+A G +E + LDTW A+EKLVD G KS+G+SNF+ + LL +IK
Sbjct: 131 -------KDANGEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIK 183
Query: 191 PVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIK 250
P+ QIE HP L Q++LI K GI V A+S G + L TPT ++
Sbjct: 184 PIHNQIEVHPALDQKKLIALCKKNGILVTAFSPLG-------RHNAELRTPTFMYDGKVQ 236
Query: 251 SIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRIND 293
+IA K+ + QV++R+ + G +PKSS +R+ +N + D
Sbjct: 237 AIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFD 279
>SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 194 bits (492), Expect = 2e-49
Identities = 114/311 (36%), Positives = 171/311 (54%), Gaps = 28/311 (9%)
Query: 9 TLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKE 68
TL NG+K+P +GLG W+ D + + A+K GYR D A Y NEKE+G+G I+E
Sbjct: 16 TLPNGDKIPSIGLGTWRSGKDETKNAVCAALKAGYRHIDTAHIYGNEKEIGEG----IRE 71
Query: 69 GLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKY 128
V R D+ V SKLW + H VP ALE+TL DL L+Y+D + IH+P A P E+
Sbjct: 72 SGVPRTDIWVTSKLWCNAHRAGLVPLALEKTLQDLNLEYIDAYLIHWPFALLSGP--EEL 129
Query: 129 PPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGAR 188
P KG + E VP+ +TW+A+E+L++ GK++ +GISNF+ + +L+ A+
Sbjct: 130 PRN--------EKGELIYEDVPIEETWQAMEELLETGKVRYIGISNFNNEYLDRVLKIAK 181
Query: 189 IKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNT--PTLFEH 246
+KP Q+E HPYL Q ++ K I V AYS A N+ L EH
Sbjct: 182 VKPTIHQMELHPYLPQTEYLEKHKKLQIHVSAYSPLA-------NQNDAYNSDISKLIEH 234
Query: 247 DTIKSIASK--HKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQ 304
T+ IA+ +TP + + WA + G +++PKS + R++ N + LTD E++
Sbjct: 235 KTLVDIANARGEGITPANIAISWAVKRGTSVLPKSVNESRIVSNFLY---IPLTDKEMEA 291
Query: 305 ISGLNQNIRFN 315
I+ + RF+
Sbjct: 292 INNIGVVRRFS 302
>At2g37770 [R] KOG1577 Aldo/keto reductase family proteins
Length = 290
Score = 194 bits (492), Expect = 2e-49
Identities = 106/284 (37%), Positives = 157/284 (54%), Gaps = 22/284 (7%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
LN G K P VGLG W+ + D + A+KIGYR D AQ Y NEKE+G + + ++
Sbjct: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69
Query: 70 LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYP 129
+VKREDL + SKLW + H P +VP AL RTL DLQL+YVD++ IH+P K
Sbjct: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK--------- 120
Query: 130 PGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARI 189
G ++ +P TW+A+E L D GK +++G+SNFS + DLL AR+
Sbjct: 121 ----KGSVGIKPENLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174
Query: 190 KPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTI 249
P Q+E HP Q +L ++ K+ G+ + AYS G L++ + ++ +
Sbjct: 175 PPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKS-------DVLKNPIL 227
Query: 250 KSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRIND 293
+A K +P QV LRW Q G +++PKS+ + R+ +N + D
Sbjct: 228 NMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFD 271
>7302301 [R] KOG1577 Aldo/keto reductase family proteins
Length = 311
Score = 187 bits (475), Expect = 2e-47
Identities = 112/310 (36%), Positives = 163/310 (52%), Gaps = 24/310 (7%)
Query: 1 MTYLAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQ 60
MT LA T+ LNNG +MP +GLG WK A+ +GYR D A Y NE EVGQ
Sbjct: 1 MTNLAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQ 60
Query: 61 GVNRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFK 120
++ I EG+V RE++ V +KL H P V RA +LS+L L+YVD++ +H P+ K
Sbjct: 61 AISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK 120
Query: 121 PVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALI 180
F+ + G +E V LDTWR +EKLVD G +S+G+SNF+ A
Sbjct: 121 -----------FH--NDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQT 167
Query: 181 QDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNT 240
+ +L RI+PV Q+E HP Q +L ++ K G+ + AY + A
Sbjct: 168 ERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLA-------RPQPARQW 220
Query: 241 PTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDD 300
P + +++A K+ T Q+ LR+ Q G+ +PKSS K R+ +N R+ D DD
Sbjct: 221 PPFLYDEHAQNLAKKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRVFDFELSPDD 280
Query: 301 ELKQISGLNQ 310
++G+ Q
Sbjct: 281 ----VAGMEQ 286
>7294572 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 186 bits (473), Expect = 3e-47
Identities = 109/310 (35%), Positives = 166/310 (53%), Gaps = 16/310 (5%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
LA TV LNNG +MP++GLG + ++ + AI +GYR D A Y NE EVG+ +
Sbjct: 3 LAPTVKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIR 62
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
I EG+VKRED+ +V+KLWN FH P+ V + LS+ LDY+D++ +H P+ +K V
Sbjct: 63 DKIAEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVD 122
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
+ P ED+ ++ V LDT++A+EKLV G ++S+G+SNF+ + +
Sbjct: 123 DNTLLPK-----NEDDV---LQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARV 174
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTL 243
L IKPV Q+E P L Q+ L + K + + Y+ G + K + P
Sbjct: 175 LANCEIKPVTNQVECSPALNQKALTAFCKKNDVTLTGYTPLG-------KPKPDIQKPDF 227
Query: 244 FEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELK 303
+ IA K+ T Q++LR+ G+ IPKSS R+ +N I D LT +E+
Sbjct: 228 IYSPEVAVIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFD-FELTAEEMA 286
Query: 304 QISGLNQNIR 313
+ G + R
Sbjct: 287 VLDGYHTGER 296
>7292408 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 186 bits (473), Expect = 3e-47
Identities = 106/283 (37%), Positives = 151/283 (52%), Gaps = 15/283 (5%)
Query: 11 NNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGL 70
NNG ++ +GLG + C AI +GYR D A Y NE EVG V R I EG+
Sbjct: 11 NNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEGV 70
Query: 71 VKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPP 130
+KRED+ + +KLW FH P V A +TL + L YVD++ +H+P ++ +E P
Sbjct: 71 IKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMP- 129
Query: 131 GFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIK 190
+AKG +E + LDTWR +EKLV+ G KS+G+SNF+ + LL +IK
Sbjct: 130 -------TDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLLANCKIK 182
Query: 191 PVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIK 250
P+ QIE HP L Q++LI K I V AY G A TP ++
Sbjct: 183 PIHNQIECHPALNQKKLIALCKKNDIVVTAYCPLG-------RPNPAEKTPNYIYDAKVQ 235
Query: 251 SIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRIND 293
+I K+K + QV+LR+ + G +PKSS +R+ +N +I D
Sbjct: 236 AIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEENFQIFD 278
>Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins
Length = 307
Score = 186 bits (471), Expect = 5e-47
Identities = 111/314 (35%), Positives = 166/314 (52%), Gaps = 32/314 (10%)
Query: 16 MPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVKRED 75
+P VGL WK + + EAI GYR FD A Y NE+EVG G+ IKEG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 76 LVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYTG 135
L + +KLW + H V A ++L L+L+Y+D++ IH+P+ FKP +P +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP-----PHPEWIMSC 118
Query: 136 KE-DEAKGHIEEEQVPL-------------LDTWRALEKLVDQGKIKSLGISNFSGALIQ 181
E H + +PL LDTW A+E LV G +K++G+SNF+ ++
Sbjct: 119 SELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLE 178
Query: 182 DLLR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALN 239
LL G R KP+ QIE HPYLTQ+ LI + ++ + V AY G +
Sbjct: 179 RLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG----------GSCE 228
Query: 240 TPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTD 299
L ++ IK IA +H +P Q+L+R+ Q + +IP S + +N+++ D LT
Sbjct: 229 GVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFD-FELTQ 287
Query: 300 DELKQISGLNQNIR 313
++ I LN+N+R
Sbjct: 288 HDMDNILSLNRNLR 301
>Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins
Length = 384
Score = 185 bits (470), Expect = 7e-47
Identities = 128/373 (34%), Positives = 185/373 (49%), Gaps = 65/373 (17%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+A V L+ KMP+VGLG W+ + + AI YR D A Y N+ EVG+ +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQ 60
Query: 64 RAIKEGLVKREDLVVVSKL------WNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPL 117
I+E V REDL +VSK+ W +F V +A E+TL DL+L Y+D++ IH+P
Sbjct: 61 EKIQEKAVMREDLFIVSKVHMAHLVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 120
Query: 118 AFKP-------VPFDEKYPPG--------------------FYTGKE---DEAKGHIEEE 147
FK V F + P TG + + KG++
Sbjct: 121 GFKSLKKWYADVVFSKHQDPETLLNRTKCPDADSSKLFILYLQTGDDFFPKDDKGNMISG 180
Query: 148 QVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLR--GARIKPVA------------ 193
+ LD W A+E+LVD+G +K+LG+SNF+ I+ LL G + KPV
Sbjct: 181 KGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQNSLGTMQNRA 240
Query: 194 ----------LQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTL 243
LQ+E HPYLTQE+LI+Y + GI V AYS G + + P+L
Sbjct: 241 GFPRDEDCLLLQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPED----PSL 296
Query: 244 FEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELK 303
E IK IA+KHK T QVL+R+ Q + +IPKS +++N+++ D L+D+E+
Sbjct: 297 LEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFD-FKLSDEEMA 355
Query: 304 QISGLNQNIRFND 316
I N+N R D
Sbjct: 356 TILSFNRNWRAFD 368
>CE24244 [R] KOG1577 Aldo/keto reductase family proteins
Length = 339
Score = 185 bits (470), Expect = 7e-47
Identities = 104/315 (33%), Positives = 177/315 (56%), Gaps = 11/315 (3%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+A+TVTLN+G +MP++G G W++P ++ A+++ +A++ GYR D A + N++EV G+
Sbjct: 3 IADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGIK 62
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
K V+RE+L + SK+WN++H + + ++ L + Y+D+ IH+P +
Sbjct: 63 DWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWA--- 119
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
E PPG A G + V L+TW+ALE GKI+S+G++NF+ ++ +
Sbjct: 120 --EDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQV 177
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFG-PVSFLELENKKALNTPT 242
IKP LQ+E +P+L QE + ++ + GI + A+ G P S L +++ P
Sbjct: 178 WTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHE----DPN 233
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
L ++T++SIA H + QVL+RWA + KSS+ +R+ N+ I LT E+
Sbjct: 234 LLYNETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNINI-FKFRLTSQEI 292
Query: 303 KQISGLNQNIRFNDP 317
+I LN + R +P
Sbjct: 293 ARIKALNIDFRILNP 307
>Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins
Length = 310
Score = 182 bits (463), Expect = 4e-46
Identities = 118/317 (37%), Positives = 169/317 (53%), Gaps = 36/317 (11%)
Query: 5 AETVTLNNGEKMPLVGLGCWK---MPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQG 61
+ +V LN+G MP++G G + P A+ AI +G+R D A Y NE+EVGQ
Sbjct: 7 SHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQA 66
Query: 62 VNRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKP 121
+ I +G VKRE++ KLW +F + V ALER+L L DYVD+F IH P A KP
Sbjct: 67 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKP 126
Query: 122 VPFDEKYPPGFYTGKE---DEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGA 178
GKE +A G I E V L DTW E D+ K+ L ++
Sbjct: 127 -------------GKELLPKDASGEIILETVELCDTW---ENQGDKHKLLELILNK---- 166
Query: 179 LIQDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKAL 238
G R KP Q+E HPYL Q +L+++ K+ I +VAYS+ G + +
Sbjct: 167 ------PGLRYKPTCNQVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDP--- 217
Query: 239 NTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLT 298
+ P L E +KSIA KH +P QV LR+ Q G+ ++ KS +ER+ +N +I D LT
Sbjct: 218 DCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFD-FELT 276
Query: 299 DDELKQISGLNQNIRFN 315
+++K I GLN+N+R++
Sbjct: 277 PEDMKAIDGLNRNLRYD 293
>At3g53880 [R] KOG1577 Aldo/keto reductase family proteins
Length = 315
Score = 181 bits (460), Expect = 1e-45
Identities = 104/282 (36%), Positives = 154/282 (53%), Gaps = 22/282 (7%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
LN G K+P VGLG W+ V D + A+KIGY+ D A Y NE E+G+ + + +G
Sbjct: 10 LNTGAKIPSVGLGTWQAAPGVVGDAVAAAVKIGYQHIDCASRYGNEIEIGKVLKKLFDDG 69
Query: 70 LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYP 129
+VKRE L + SK+W + P +V AL RTL DLQLDYVD++ +H+P+ K
Sbjct: 70 VVKREKLFITSKIWLTDLDPPDVQDALNRTLQDLQLDYVDLYLMHWPVRLK--------- 120
Query: 130 PGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARI 189
G D +I +P TW+A+E LVD GK +++G+SNFS + DL+ AR+
Sbjct: 121 ----KGTVDFKPENIMPIDIP--STWKAMEALVDSGKARAIGVSNFSTKKLSDLVEAARV 174
Query: 190 KPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTI 249
P Q+E HP Q +L ++ K+ GI + YS G ++ L +P I
Sbjct: 175 PPAVNQVECHPSWQQHKLHEFCKSKGIHLSGYSPLGSPGTTWVK-ADVLKSP------VI 227
Query: 250 KSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRI 291
+ IA + +P Q LRW Q G +I+PKS+ + R+ +N +
Sbjct: 228 EMIAKEIGKSPAQTALRWGLQMGHSILPKSTNEGRIRENFDV 269
>CE17230 [R] KOG1577 Aldo/keto reductase family proteins
Length = 333
Score = 181 bits (459), Expect = 1e-45
Identities = 104/309 (33%), Positives = 167/309 (53%), Gaps = 11/309 (3%)
Query: 6 ETVTLNNGEKMPLVGLGCWKMPNDV-CADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNR 64
+++ LN G ++PL GLG W++ ++ + A+ GYRL D A Y NE +G+ ++
Sbjct: 4 DSIPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHE 63
Query: 65 AIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPF 124
I G +KRED+ V SKL + H P++VP+ +E L LQL+Y+D++ IH P F
Sbjct: 64 YISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPF----- 118
Query: 125 DEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLL 184
K+ G + + G + ++ +DTWRALEKL +GK+K+LG+SNFS +Q L
Sbjct: 119 --KHQEGSFAPLME--NGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALY 174
Query: 185 RGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLF 244
A +KP Q+E H Y Q+ L K G+ V AY+ G
Sbjct: 175 DAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPEGDPL 234
Query: 245 EHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQ 304
+K +A+K+ T Q+L+R TQ+GI+ IPKS +R+++N+ D L+D+++
Sbjct: 235 LEPIVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVENISTFD-FKLSDEDMHT 293
Query: 305 ISGLNQNIR 313
++ + R
Sbjct: 294 LNSIETRTR 302
>At5g62420 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 179 bits (454), Expect = 5e-45
Identities = 111/308 (36%), Positives = 165/308 (53%), Gaps = 24/308 (7%)
Query: 5 AETVTLNNGEKMPLVGLG--CWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGV 62
++ L GE +PL+G+G C + + +++AIKIGYR FD A+ Y +E+ +G +
Sbjct: 3 SDVARLRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTAL 62
Query: 63 NRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPV 122
+AI G V+R+DL V SKLW+S HH + AL +TL + LDY+D + +H+P+ KP
Sbjct: 63 GQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIKLKP- 119
Query: 123 PFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQD 182
E P KEDE E+ + + +TW+ +E+ ++ G +S+G+SNFS I D
Sbjct: 120 GVSEPIP------KEDEF-----EKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFD 168
Query: 183 LLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPT 242
LL A + P Q+E HP Q +L K + I V YS G +
Sbjct: 169 LLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPG-------NCWGSTA 221
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
+ EH IKSIA KH TP QV LRW G ++I KS R+++N R + + L D +L
Sbjct: 222 VIEHPIIKSIALKHNATPAQVALRWGMSKGASVIVKSFNGARMIENKRALE-IKLDDQDL 280
Query: 303 KQISGLNQ 310
I L +
Sbjct: 281 SLIDHLEE 288
>YDR368w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 166 bits (420), Expect = 4e-41
Identities = 106/309 (34%), Positives = 162/309 (52%), Gaps = 31/309 (10%)
Query: 7 TVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAI 66
T+ LN G +P++G G W+ ++ + A+K GYR D A Y NE+EVG RAI
Sbjct: 11 TLKLNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVG----RAI 66
Query: 67 KEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDE 126
K+ V RE++ + +KLW + AL ++L L LDYVD++ +H+P+ K +
Sbjct: 67 KDSGVPREEIFITTKLWGTEQRDPEA--ALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTD 124
Query: 127 KYP---PGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
P G D I+ ++ + TW +++L GK K++G+SNFS I++L
Sbjct: 125 GNVLCIPTLEDGTVD-----IDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKEL 179
Query: 184 LRGA--RIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTP 241
L ++ P QIE HP L Q+ LI + K GI V AYS FG + N P
Sbjct: 180 LESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFG-----------SANAP 228
Query: 242 TLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDE 301
L + I +A KH V P Q+++ W+ Q G ++ KS ER++ N +I TL +D+
Sbjct: 229 -LLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKI---FTLPEDD 284
Query: 302 LKQISGLNQ 310
K IS L++
Sbjct: 285 FKTISNLSK 293
>YOR120w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 163 bits (412), Expect = 4e-40
Identities = 101/305 (33%), Positives = 160/305 (52%), Gaps = 25/305 (8%)
Query: 8 VTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIK 67
++LN G ++P +GLG W+ + + A+K GYR D A Y NE +VGQ AIK
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQ----AIK 67
Query: 68 EGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEK 127
+ V RE++ V +KLW + HH V AL+++L L LDYVD++ +H+P P +
Sbjct: 68 DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNE 125
Query: 128 YPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLL--R 185
T K+ ++ + TW +++L GK K++G+SNFS ++DLL +
Sbjct: 126 DILSVPTKKDGSRA--VDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQ 183
Query: 186 GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFE 245
G ++ P A Q+E HP L Q+ LI + K+ GI V AYS G L +
Sbjct: 184 GNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTD------------APLLK 231
Query: 246 HDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQI 305
I IA K+ V P V++ W Q G ++PKS +R+ N +I TL+ ++ + I
Sbjct: 232 EPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKI---FTLSTEDFEAI 288
Query: 306 SGLNQ 310
+ +++
Sbjct: 289 NNISK 293
>7294573 [R] KOG1577 Aldo/keto reductase family proteins
Length = 252
Score = 160 bits (406), Expect = 2e-39
Identities = 93/265 (35%), Positives = 146/265 (55%), Gaps = 18/265 (6%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
LA TV LNNG +MP++GLG + + C + A+++GYR D A Y NE +G+ +
Sbjct: 3 LAPTVKLNNGYEMPILGLGTYNLKKSRCEAAVCHALEMGYRHIDTAYLYRNEGIIGKVLA 62
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
+ I + +KRE + +V+KLW+ +H P V A + L L +DY+D++ +H P+ +
Sbjct: 63 KLIGDQKLKREQVFLVTKLWDIYHEPKMVKYACDMQLKLLGVDYIDLYLMHSPVGVDYIS 122
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
++ P G + V +DT+R++E+LV G ++SLG+SNF+ ++ L
Sbjct: 123 DEDLMP---------HENGQLRTNDVDYVDTYRSMEQLVHLGLVRSLGLSNFNANQLKRL 173
Query: 184 LRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALN-TPT 242
L +IKP LQIE HP L Q LI+ K I VVAYS G KA N P
Sbjct: 174 LENCQIKPANLQIECHPELVQVPLIELCKFHNITVVAYSPLG--------RPKACNPLPD 225
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRW 267
+ + ++A+K+ TP Q++LR+
Sbjct: 226 YYTDSKLLALAAKYGKTPAQIILRY 250
>CE10936 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 157 bits (396), Expect = 3e-38
Identities = 103/319 (32%), Positives = 161/319 (50%), Gaps = 43/319 (13%)
Query: 7 TVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAI 66
++ LN G PL+GLG +K+ D + A+ GYRLFD A+ Y NEKE+G + +
Sbjct: 2 SIKLNTGYDCPLIGLGTYKIIGDQVLPVLDAALTAGYRLFDTAKVYNNEKEIGDALEILL 61
Query: 67 KEGLVKREDLVVVSKLWNSFHHP---DNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
+ +KRED+ + +K+ HP +NV + ++ +LS L+ Y+D++ IH
Sbjct: 62 PKHNLKREDIFITTKM-----HPNTVENVKKLVDESLSLLKTSYIDMYLIH--------- 107
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
YP F G +D + + TW L + + GKI+S+G+S+F +++L
Sbjct: 108 ----YPKSFDYGDQDPMNKTLR------IATWNDLWECKNAGKIRSVGVSSFEIRHLEEL 157
Query: 184 L-RGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPT 242
G P Q+E+HP+ T+E L Y K+ GI A+SS A + T
Sbjct: 158 KDLGKNFPPCCNQVEYHPHFTREELKNYCKSEGIFFQAFSSL------------ARHNET 205
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
L + I +A K+ V VLL WAT + IIPKS+ ERL NL+ + L ++E+
Sbjct: 206 LLSSEIITRLAEKYHVPKTTVLLSWATSQKVGIIPKSTNPERLAQNLK---TVLLEEEEV 262
Query: 303 KQISGLNQNIRFNDPWEWL 321
K+I LN + + WL
Sbjct: 263 KKICNLNLDKHYVRTTGWL 281
>Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins
Length = 280
Score = 154 bits (388), Expect = 2e-37
Identities = 104/312 (33%), Positives = 152/312 (48%), Gaps = 61/312 (19%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+A + LNNG KMP++GLG WK P + + AI +GY D A +E EVG +
Sbjct: 1 MASHLVLNNGTKMPILGLGTWKSPPGRVTEAVNVAINVGYCHIDCAH---HENEVGVAIQ 57
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
++E +VKRE+L +V+ W FPL
Sbjct: 58 EKLREQVVKREELFIVT--WEGI----------------------------FPL------ 81
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
G++ +LDTW A+E+LVD+ +K++GISNF+ ++ L
Sbjct: 82 ---------------NELGNVVPSDTNILDTWAAMEELVDEWLMKAIGISNFNHLQVERL 126
Query: 184 LR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTP 241
L G + KPV QIE HPYLTQE+LI+Y ++ GI V AYS G S + + P
Sbjct: 127 LNKPGLKYKPVVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPVGTPSRPWVNPE----DP 182
Query: 242 TLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDE 301
+L IK+IA+KH T QVL+R+ Q + +IPKS E + DN ++ D L +
Sbjct: 183 SLLRDPRIKAIAAKHNKTTAQVLIRFPMQRNLGVIPKSVTPELIADNFKVFD-FELNSQD 241
Query: 302 LKQISGLNQNIR 313
+ + N+N R
Sbjct: 242 MTALLSYNRNWR 253
>CE06776 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 154 bits (388), Expect = 2e-37
Identities = 93/310 (30%), Positives = 153/310 (49%), Gaps = 26/310 (8%)
Query: 1 MTYLAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQ 60
M+ ++ L+NG +MP++GLG W+ + A+K GYRL D A Y NE+ +G
Sbjct: 1 MSSATASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGT 60
Query: 61 GVNRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFK 120
+ ++EG+VKRE+L + +K W P + L +L LQL+YVD++ H P AF
Sbjct: 61 AIKELLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAF- 119
Query: 121 PVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALI 180
D+ HI P+ D WR + + G K++G+SN++ I
Sbjct: 120 ----------------NDDMSEHIAS---PVEDVWRQFDAVYKAGLAKAVGVSNWNNDQI 160
Query: 181 QDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGP---VSFLELENKKA 237
L Q+E H Y Q + + K I V +Y++ G V+F +K
Sbjct: 161 SRALALGLTPVHNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKL 220
Query: 238 --LNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDAL 295
P+ + + ++A K TP QVLLR+A G AI+PKS ++ R+ +N + D
Sbjct: 221 DWAPAPSDLQDQNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFD-F 279
Query: 296 TLTDDELKQI 305
+LT++++ ++
Sbjct: 280 SLTEEDIAKL 289
>At5g01670 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 154 bits (388), Expect = 2e-37
Identities = 91/288 (31%), Positives = 148/288 (50%), Gaps = 27/288 (9%)
Query: 6 ETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRA 65
E+ L +G K+P VGLG W+ + + ++ GYR D A +Y +++EVGQG+ RA
Sbjct: 14 ESFRLLSGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRA 73
Query: 66 IKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFD 125
+ GL +R DL V SKLW + P+ V AL+ TL +LQL+Y+D++ IH+P+ +
Sbjct: 74 MHAGL-ERRDLFVTSKLWCTELSPERVRPALQNTLKELQLEYLDLYLIHWPIRLRE---G 129
Query: 126 EKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLR 185
PP + + +G WR +E L ++++G+ NF+ + LL
Sbjct: 130 ASKPPKAGDVLDFDMEG-----------VWREMENLSKDSLVRNIGVCNFTVTKLNKLLG 178
Query: 186 GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFE 245
A + P Q+E HP +R++++ K ++ AYS G L
Sbjct: 179 FAELIPAVCQMEMHPGWRNDRILEFCKKN--EIHAYSPLGSQE----------GGRDLIH 226
Query: 246 HDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRIND 293
T+ IA K TP Q+L++W Q G ++IPKS ER+ +N+++ D
Sbjct: 227 DQTVDRIAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKVFD 274
>At1g59960 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 153 bits (386), Expect = 4e-37
Identities = 101/298 (33%), Positives = 159/298 (52%), Gaps = 31/298 (10%)
Query: 16 MPLVGLGCWKMP---NDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVK 72
MP++G G P + + + EAIK+GYR FD + Y E+ +G+ + A+ GLV+
Sbjct: 21 MPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVR 80
Query: 73 -REDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPG 131
R + V +KLW + H V A++R+L +L+LDY+D++ IH+P++ KP + K+P
Sbjct: 81 SRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKY--KFP-- 136
Query: 132 FYTGKEDEAKGHIEEEQVPLLD---TWRALEKLVDQGKIKSLGISNFSGALIQDLLRGAR 188
I+E+ +D W +E+ G K +G+SNFS +Q +L A
Sbjct: 137 ------------IDEDDFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKLQHILSIAT 184
Query: 189 IKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDT 248
I P Q+E P Q +L + ++ I V AYS G TP + E D
Sbjct: 185 IPPSVNQVEMSPIWQQRKLRELCRSNDIVVTAYSVLG-------SRGAFWGTPKIMESDV 237
Query: 249 IKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQIS 306
+K IA + T QV +RWA + G++++ KS KERL +NL+I D +LT+DE ++IS
Sbjct: 238 LKEIAEAKEKTVAQVSMRWAYEQGVSMVVKSFTKERLEENLKIFD-WSLTEDETQRIS 294
>At1g59950 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 152 bits (384), Expect = 6e-37
Identities = 103/298 (34%), Positives = 159/298 (52%), Gaps = 31/298 (10%)
Query: 16 MPLVGLGCWKMPND---VCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVK 72
MP++ LG P V + EAIK+GYR FD + Y E+ +G+ + A+ GL++
Sbjct: 15 MPVLALGTAASPPPEPIVLKRTVLEAIKLGYRHFDTSPRYQTEEPLGEALAEAVSLGLIQ 74
Query: 73 -REDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPG 131
R +L V SKLW + H V A++R+L L+LDY+D++ IH+P++ KP + K+P
Sbjct: 75 SRSELFVTSKLWCADAHGGLVVPAIQRSLETLKLDYLDLYLIHWPVSSKPGKY--KFP-- 130
Query: 132 FYTGKEDEAKGHIEEEQVPLLD---TWRALEKLVDQGKIKSLGISNFSGALIQDLLRGAR 188
IEE+ +D W +E+ G K +G+SNFS +Q +L A+
Sbjct: 131 ------------IEEDDFLPMDYETVWSEMEECQRLGVAKCIGVSNFSCKKLQHILSIAK 178
Query: 189 IKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDT 248
I P Q+E P Q +L + K+ GI V AYS G T + E D
Sbjct: 179 IPPSVNQVEMSPVWQQRKLRELCKSKGIVVTAYSVLG-------SRGAFWGTHKIMESDV 231
Query: 249 IKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQIS 306
+K IA T QV +RWA + G++++ KS +K+RL +NL+I D +LT++E ++IS
Sbjct: 232 LKEIAEAKGKTVAQVSMRWAYEEGVSMVVKSFRKDRLEENLKIFD-WSLTEEEKQRIS 288
>Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins
Length = 418
Score = 151 bits (382), Expect = 1e-36
Identities = 107/325 (32%), Positives = 159/325 (48%), Gaps = 55/325 (16%)
Query: 5 AETVTLNNGEKMPLVGLGCWK---MPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQG 61
+ +V LN+G MP++G G + P + AI G+R D A Y NE+EVG+
Sbjct: 6 SHSVRLNDGHVMPMLGFGTYAPDHTPKSKAGEATEVAIDAGFRHIDAAFFYQNEEEVGKA 65
Query: 62 VNRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAF-- 119
+ I +G VKRED+ ++LW +F P+ V ALE +L LQLDYVD+F IH PLA
Sbjct: 66 IREKIADGPVKREDIFYTTELWTTFFRPELVRPALEGSLKKLQLDYVDLFIIHNPLAMKL 125
Query: 120 ----------KPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKS 169
KP + PG +D A G+I + V L DTW ALEK + G KS
Sbjct: 126 LRRQKGNSHRKPSSLSSVFQPGEELLPKD-ASGNIIFDTVDLRDTWEALEKCKEAGLTKS 184
Query: 170 LGISNFSGALIQDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSF 229
+G+SNF+ L++ +L KP +++ P Q +L+++ K+ I +VAY + ++
Sbjct: 185 IGVSNFNHKLLELILN----KP---GLKYKPTCNQSKLLEFCKSKDIVLVAYRA---LAS 234
Query: 230 LELENKKALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNL 289
N ++P L E T+KSIA K+ +P QV
Sbjct: 235 HRDPNWMDPDSPYLLEEPTLKSIAKKYNRSPGQVF------------------------- 269
Query: 290 RINDALTLTDDELKQISGLNQNIRF 314
LT +++K GLN+N R+
Sbjct: 270 ----DFELTPEDMKATDGLNRNFRY 290
>Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins
Length = 222
Score = 149 bits (377), Expect = 4e-36
Identities = 97/256 (37%), Positives = 134/256 (51%), Gaps = 42/256 (16%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+A V LN KMP+VGLG WK P + + AI GYR D A Y NE EVG+ +
Sbjct: 1 MAIFVELNTKAKMPIVGLGTWKSPLGKVKEVVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
I+E VKREDL +++KLW +F ER L
Sbjct: 61 EKIQEKAVKREDLFIINKLWPTF---------FERPLG---------------------- 89
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
Y G ++D+ KG++ + LD W A+E+LVD+G +K+LG+SNF+ I+ L
Sbjct: 90 ----YKSGDDFFRKDD-KGNMIGGKAMFLDAWEAMEELVDEGLVKALGVSNFNHFQIERL 144
Query: 184 LR--GARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTP 241
L G + KPV Q+E HPYLTQE+LI+Y + GI ++AYS G L + + P
Sbjct: 145 LNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITIMAYSPLGSPDRLWAKPE----DP 200
Query: 242 TLFEHDTIKSIASKHK 257
+L E IK IA++HK
Sbjct: 201 SLLEDPKIKEIAARHK 216
>CE27788 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 146 bits (369), Expect = 4e-35
Identities = 92/292 (31%), Positives = 145/292 (49%), Gaps = 27/292 (9%)
Query: 9 TLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKE 68
TL+NG MP +GLG W+M + I A+ GYR D A Y NE ++G + E
Sbjct: 9 TLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDALAELFAE 68
Query: 69 GLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKY 128
G++KRED+ + +K + PD V AL +L L+LDYVD++ H P + K D +
Sbjct: 69 GILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKD---DGSF 125
Query: 129 PPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGAR 188
V + D WR EK+ G K++G+SNF+ + I ++ +
Sbjct: 126 -----------------RSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQK 168
Query: 189 IKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLEL--ENKKAL-----NTP 241
+ A Q+E H YL Q+ + K I + AY++ G + + N + L N+
Sbjct: 169 VPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGRMSVVGSNGRPLFESTQNSE 228
Query: 242 TLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRIND 293
+K++A K+ TP Q+LLR + GI +IPK++ ER+ +N+ I D
Sbjct: 229 NEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTNPERMKENINIFD 280
>YJR096w [R] KOG1577 Aldo/keto reductase family proteins
Length = 282
Score = 143 bits (360), Expect = 4e-34
Identities = 96/299 (32%), Positives = 151/299 (50%), Gaps = 48/299 (16%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKE- 68
L+NG K+P + LG + +P A+ +YE +K GYR FD A Y NEKEVG G+ + + E
Sbjct: 8 LSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNED 67
Query: 69 -GLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQ-LDYVDIFYIHFPLAFKPVPFDE 126
G KRE++ +KLWNS + A+ + L+++ L Y+D+ IH PL
Sbjct: 68 PGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL--------- 118
Query: 127 KYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRG 186
E L+TWRA+++ VD+G +KS+G+SN+ I +LL
Sbjct: 119 -------------------EGSKLRLETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNW 159
Query: 187 ARI--KPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLF 244
+ KPV QIE P++ ++ L Y K+ G+ V A F L + + P L
Sbjct: 160 PELKHKPVVNQIEISPWIMRQELADYCKSKGLVVEA--------FAPLCHGYKMTNPDLL 211
Query: 245 EHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELK 303
+ + + P QVL+RW+ Q+G +PK+ +RL NL + L+D+++K
Sbjct: 212 K------VCKEVDRNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYN-FELSDEQMK 263
>YBR149w [R] KOG1577 Aldo/keto reductase family proteins
Length = 344
Score = 142 bits (358), Expect = 7e-34
Identities = 96/316 (30%), Positives = 165/316 (51%), Gaps = 27/316 (8%)
Query: 9 TLNNGEKMPLVGLGCWKMPNDVCADQ---IYEAIKIGYRLFDGAQDYANEKEVGQGVNRA 65
+LNNG ++P +GLG P++ A+ + AIK GYR D A Y E VG+ +
Sbjct: 26 SLNNGVRIPALGLGTAN-PHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84
Query: 66 IKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFD 125
+++G +KREDL + +K+W D V R+L +L L L+YVD+ H+PL F+ + D
Sbjct: 85 LEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK-D 141
Query: 126 EKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLV---DQGKIKSLGISNFSGALIQD 182
K G D++ + L+T++ LEK+ + +++++G+SNFS ++
Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201
Query: 183 LLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPT 242
L++ R+KP Q+E HP+L Q L K+ I + AYS G + P
Sbjct: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG-----------SHGAPN 250
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
L + +K +A K+ VT +L+ + + G +IP+S R+ ++ + +LT DEL
Sbjct: 251 L-KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSI---EFASLTKDEL 306
Query: 303 KQISGLNQN--IRFND 316
++++ + +RF D
Sbjct: 307 QELNDFGEKYPVRFID 322
>CE10934 [R] KOG1577 Aldo/keto reductase family proteins
Length = 297
Score = 141 bits (356), Expect = 1e-33
Identities = 87/313 (27%), Positives = 157/313 (49%), Gaps = 33/313 (10%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
LN+G +P VG G +K+ + I A+ GYR+FD A+ Y NEKE+G+ + + +
Sbjct: 15 LNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKH 74
Query: 70 LVKREDLVVVSKLWNSFHHPDNVPRA-LERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKY 128
+ R D+ + SK + + R +E +L LQ DY+D++ +H+P KP
Sbjct: 75 GLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYP---KP------- 124
Query: 129 PPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGAR 188
+++ + E ++ + LE+ GK++S+G+SN+ +++L A+
Sbjct: 125 -----NDSDNDDVNNAEYRKI----AYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAK 175
Query: 189 IKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDT 248
+ P A Q+E+HP+ + L KY K I A+SS A + P L E
Sbjct: 176 VPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFSSL------------ARHEPKLIEDPV 223
Query: 249 IKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGL 308
+ +A KH + VLL WA + + I+PKS R+++N ++ D + LT ++++ ++ L
Sbjct: 224 VVELAKKHNTSVPLVLLAWALRQNVGIVPKSVTPSRIVENFKVID-IALTPEDIQSLTAL 282
Query: 309 NQNIRFNDPWEWL 321
++ + WL
Sbjct: 283 DRGQHYIRCTGWL 295
>SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 275
Score = 139 bits (349), Expect = 7e-33
Identities = 89/316 (28%), Positives = 161/316 (50%), Gaps = 50/316 (15%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
L V LNNG K P G + + C D +Y A++ GYR D AQ Y NE + G+ +
Sbjct: 2 LGSFVKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAIL 61
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVP 123
+ ++E KRED+ SKL N + +++ ++ L Y+D+F +H P +
Sbjct: 62 KFMEETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYGDR--- 117
Query: 124 FDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL 183
+++W+ALEK V++GK++++G+SNF IQ+L
Sbjct: 118 ----------------------------IESWKALEKGVEEGKLRAIGVSNFGPHHIQEL 149
Query: 184 LRG-ARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPT 242
L +I P QIE HP+ +Q++++ Y ++ GIQ+ AY+ V + NK+ L
Sbjct: 150 LDSHPKIIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAPL--VHGEKFGNKQLL---- 203
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
+IASK+ + Q+++R+ Q G ++PKSS R+ +N + D ++ +++
Sbjct: 204 --------AIASKYNKSEAQIMIRYCLQRGFIVLPKSSTPRRIKENGDVFD-FEISKEDM 254
Query: 303 KQISGLNQNIRFNDPW 318
+++ L+++ ++ W
Sbjct: 255 EKLYNLDED--YHSDW 268
>CE01200 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 137 bits (346), Expect = 2e-32
Identities = 82/294 (27%), Positives = 153/294 (51%), Gaps = 32/294 (10%)
Query: 16 MPLVGLGCWKMPNDVCADQIYEA-IKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVKRE 74
MPL+G+G W++ + Q+ +A K GYR D AQ Y NE ++G+ + + + +KRE
Sbjct: 11 MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRE 70
Query: 75 DLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYT 134
D+ + SKL S ++E +LS+L+++Y+D+ IH+P G
Sbjct: 71 DIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP--------------GSSL 116
Query: 135 GKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIKPVAL 194
E+ A + E +W + +++ +GK++S+G+SNF +++L + + + P
Sbjct: 117 KSENPANKKLRVE------SWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVN 170
Query: 195 QIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIAS 254
Q+E+HP+ Q+ L+KY I AYSS G ++ + L E IK +A
Sbjct: 171 QVEYHPHFHQDDLVKYCNENNIHFQAYSSLGSPTYRK----------QLSEEPLIKELAQ 220
Query: 255 KHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGL 308
K+ V +LL +A GI+++P+++ E + N ++ L +T +++ ++ L
Sbjct: 221 KYNVEIPVLLLGFAYCQGISVLPRTTNPEHVATNFKVT-KLAITQEDIDRLLAL 273
>CE06751 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 131 bits (330), Expect = 1e-30
Identities = 88/313 (28%), Positives = 154/313 (49%), Gaps = 34/313 (10%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
L NG+++P + LG ++ D + EA+K+GYR FD A+ Y NEK++G + +
Sbjct: 4 LKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRH 63
Query: 70 LVKREDLVVVSKL--WNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEK 127
+ ED+ + SK+ ++S + + + + + +L L Y+D+ +H+P +P+ ++
Sbjct: 64 NICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYP---RPLDTEDL 120
Query: 128 YPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGA 187
E ++ DTW ALEKL +GKI+S+G+SN+ I+++
Sbjct: 121 N----------------ENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYI 164
Query: 188 RIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHD 247
I+P QIE+HP+ ++ L Y I A+S G TL
Sbjct: 165 TIEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSPLG------------RGNKTLLGDS 212
Query: 248 TIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISG 307
T++ IA HK T V+L W + ++ KS R+ +N + +L L+DDE ++I+G
Sbjct: 213 TMERIALCHKTTVANVILAWIMKGKYGVVAKSVTPSRVAENY-TSLSLELSDDEFEKING 271
Query: 308 LNQNIRFNDPWEW 320
LN + + W
Sbjct: 272 LNLETPYVEDRGW 284
>CE06112 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 131 bits (329), Expect = 2e-30
Identities = 87/306 (28%), Positives = 150/306 (48%), Gaps = 31/306 (10%)
Query: 11 NNGEKMPLVGLGCWKMPNDVCAD-QIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
++G +MP +GLG ++ D I A+K GYR FD A Y NE +G + + + +
Sbjct: 15 SDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLPQF 74
Query: 70 LVKREDLVVVSKLWNSFHHP-DNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKY 128
+ RED+ + +K+ + + + L +L+ LQ DYVD+ IH Y
Sbjct: 75 GLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIH-------------Y 121
Query: 129 PPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGAR 188
P TG +D+ + + ++ W+ LEK + G+++S+G+SN+ + ++ A+
Sbjct: 122 PRDRDTGNDDDYEINKSRRKI----VWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAK 177
Query: 189 IKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDT 248
I+PV Q E+ PYLT+ L K+ I V +YSS + +
Sbjct: 178 IRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYSSL------------CWGDKEILQEKP 225
Query: 249 IKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGL 308
+ + K+ TPQ +L +A + ++IPKS+ R+ DNL + LT+DELK + L
Sbjct: 226 LVDLCQKYNQTPQAILYAFAHCSNTSMIPKSATPSRIHDNLHNTIKIKLTEDELKSLRSL 285
Query: 309 NQNIRF 314
++ F
Sbjct: 286 DKGKSF 291
>SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins
Length = 284
Score = 124 bits (311), Expect = 2e-28
Identities = 94/306 (30%), Positives = 152/306 (48%), Gaps = 53/306 (17%)
Query: 13 GEKMPL----VGLGCWKMP----NDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNR 64
G K+P+ VG +K N D + A+ G+ D A+ Y NE+EVG
Sbjct: 7 GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGV---- 62
Query: 65 AIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPF 124
A+KE V R L + SK+ H+ DN+P AL +L L DY+D++ +H P+PF
Sbjct: 63 ALKEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLH-----SPIPF 114
Query: 125 DEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLL 184
EK ++P+ + W+A+E + G + S+G+SNF +++LL
Sbjct: 115 YEK--------------------KIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELL 154
Query: 185 RGARIKPVALQIEHHP--YLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPT 242
+ + I P QIE HP Y + L+++ ++ GI V Y GP+S L + + + T
Sbjct: 155 KTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGY---GPLSPLVRDAQGPVAEFT 211
Query: 243 LFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDEL 302
KS+ SK+ V+ Q+LL+WA G+ I +SK ER+ + L D+ TL ++
Sbjct: 212 -------KSLESKYHVSDTQILLKWAYSKGVIPITTTSKIERMKECLNF-DSFTLDKADI 263
Query: 303 KQISGL 308
++ L
Sbjct: 264 DELGTL 269
>Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins
Length = 241
Score = 123 bits (309), Expect = 3e-28
Identities = 88/292 (30%), Positives = 127/292 (43%), Gaps = 80/292 (27%)
Query: 4 LAETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+A + LNNG KMP++GLG W P + + AI +GY D A Y NE +VG +
Sbjct: 1 MASHIVLNNGTKMPILGLGTWNSPPGQVTEAVKVAINVGYCHIDCAHVYQNENDVGVAIR 60
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKP-- 121
++E +VK E+L + SKL FKP
Sbjct: 61 EKLREQVVKCEELFITSKL-----------------------------------CFKPGK 85
Query: 122 --VPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGAL 179
P DE PG G++ +LDTW +E+LVD+G +K++GISNF+
Sbjct: 86 EFFPLDE---PG---------NGNVVPSNSNILDTWAGMEELVDEGLVKAIGISNFNH-- 131
Query: 180 IQDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALN 239
QE+LI+Y ++ GI V AYSSF
Sbjct: 132 -----------------------LQEKLIQYCQSKGIMVTAYSSFSSPD----RPWAKPE 164
Query: 240 TPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRI 291
P+L E IK+I +KH T QVL+ + Q + +IPKS E + +N ++
Sbjct: 165 DPSLLEDPRIKAITAKHNKTTAQVLIWFPMQRNLVVIPKSVTPECIAENFKV 216
>SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 122 bits (306), Expect = 7e-28
Identities = 88/306 (28%), Positives = 149/306 (47%), Gaps = 46/306 (15%)
Query: 7 TVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAI 66
TVTL NG +P +G G + + + C + +A+ GYR D A Y NE G+ +
Sbjct: 10 TVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWC 69
Query: 67 KEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDE 126
++ VKR D+ + SKL N + RA R+ Y+D+F I P
Sbjct: 70 EKNNVKRTDIFLTSKLANCSDYYST--RAAIRSSLHHLGTYIDLFLIQSPAG-------- 119
Query: 127 KYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRG 186
GK+ + +W+A+E+ VD G I+S+G+SN+ +Q+L
Sbjct: 120 --------GKKSR------------IASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYAS 159
Query: 187 -ARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFE 245
+ P QIE HP+L+Q+ ++KY ++ I + AYS + L ++K +
Sbjct: 160 NPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPL--THGIRLNDEKLV------- 210
Query: 246 HDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQI 305
IA K ++ Q+L+RW+ Q G I KS+KKE +L +L + + T+ DD ++++
Sbjct: 211 -----PIAKKLNISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLDVFN-FTIPDDVVQEL 264
Query: 306 SGLNQN 311
S +++
Sbjct: 265 SSFDEH 270
>YDL124w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 107 bits (267), Expect = 2e-23
Identities = 88/322 (27%), Positives = 149/322 (45%), Gaps = 49/322 (15%)
Query: 1 MTYLAETVTLNNGEKMP---LVGLGC-WKMPNDVCA-------DQIYEAIKI-GYRLFDG 48
M++ + TLNNG K+P ++G G W + A +QI A+K+ G D
Sbjct: 1 MSFHQQFFTLNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDA 60
Query: 49 AQDYANEKEVGQGVNRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYV 108
A+ Y EVG+ ++ K R + + K D+ L+ L + DYV
Sbjct: 61 AEIYRTYPEVGKALSLTEKP----RNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYV 116
Query: 109 DIFYIHFPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIK 168
D++ +H P K V + L + W+ +E+L GK K
Sbjct: 117 DLYLLHSPFVSKEV------------------------NGLSLEEAWKDMEQLYKSGKAK 152
Query: 169 SLGISNFSGALIQDLLRGARIKPVALQIEHHPYLTQER--LIKYVKNAGIQVVAYSSFGP 226
++G+SNF+ +Q +L+ A +KP QIE P+L + + K+ + I V AYS GP
Sbjct: 153 NIGVSNFAVEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGP 212
Query: 227 VSFLELENKKALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLL 286
L+ K A + F + +K ++ K+ + Q++LRW T+ G+ + SSK +R+
Sbjct: 213 -----LQKKTAQDDSQPF-FEYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRIS 266
Query: 287 DNLRINDALTLTDDELKQISGL 308
D + + LT +E+ +I+ L
Sbjct: 267 DAQNL-FSFDLTAEEVDKITEL 287
>Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins
Length = 130
Score = 92.8 bits (229), Expect = 6e-19
Identities = 44/118 (37%), Positives = 70/118 (59%), Gaps = 3/118 (2%)
Query: 7 TVTLNNGEKMPLVGLG---CWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVN 63
+V LN+G+ MP++G G K+ + + AI +GYR D A + NE+ +GQ +
Sbjct: 8 SVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIR 67
Query: 64 RAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKP 121
+ I G VKR+D+ +K+W +F P+ V R LE +L LQL Y+D++ HFP+ +P
Sbjct: 68 KKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQP 125
>CE15543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 376
Score = 92.0 bits (227), Expect = 1e-18
Identities = 95/358 (26%), Positives = 138/358 (38%), Gaps = 88/358 (24%)
Query: 7 TVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAI 66
T L+N +MPL+GLG ++ K GYRL D A+ Y EK++G A+
Sbjct: 4 TTVLSNNVEMPLIGLGTTHSGGYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGI----AV 59
Query: 67 KEGLVKREDLVVVSKLW---------NSF-----------------HHPD------NVPR 94
K V RE++ + +KLW N+F H P N
Sbjct: 60 KNCSVPREEMFLSTKLWPVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQLPDWIVNQKE 119
Query: 95 ALERTLSDLQLDYVD----IFYIHFPLAFKPVP--------------FDEKYPPGFYTGK 136
E+T ++L Y D + F LAF + K P K
Sbjct: 120 TKEKTWRQMELLYEDGKFGFCFKCFKLAFGEATSYIALKISCNELCKLNLKLPMSISRSK 179
Query: 137 EDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIKPVALQI 196
+ I E V +S+G+SN+S + +LL A I P A Q+
Sbjct: 180 NPQTNFTIITEHV------------------RSIGVSNYSIEDLDELLEFASILPHANQV 221
Query: 197 EHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIASKH 256
E HP+ Q L Y GI + Y +LE E T+ IASK+
Sbjct: 222 ELHPWFHQADLKNYCDELGILTMGYCPLAKGKYLEDE--------------TLCKIASKY 267
Query: 257 KVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDD--ELKQISGLNQNI 312
+ +P Q+ LRW+ Q + +PKS+ RL +N + D +D L S N+ I
Sbjct: 268 QKSPAQICLRWSIQQNVPTVPKSTDCRRLKENTNVFDFELSAEDMNTLNSFSSQNRKI 325
>SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 276
Score = 84.0 bits (206), Expect = 3e-16
Identities = 64/261 (24%), Positives = 120/261 (45%), Gaps = 44/261 (16%)
Query: 31 CADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGL-VKREDLVVVSKLWNSFHHP 89
C Q+ EA+ +G R+ D A Y NEKE Q + + + +KRED+ +++K+ +S
Sbjct: 26 CYQQVIEALSLGIRVIDSAITYRNEKECEQAIQDFCHQNVNIKREDITLITKIPDSLQGF 85
Query: 90 DNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQV 149
+ +A+E++L +D+ IH P K+P V
Sbjct: 86 ERTWKAVEQSLRRTGRPKLDVVLIHSP----------KWP-------------------V 116
Query: 150 PLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIKPVALQIEHHPYLTQERLIK 209
+++WRAL + +G+I +G+SN++ +++++ P Q+E + + +
Sbjct: 117 RRIESWRALLQHQKEGRINKIGVSNYNIHHLEEIISLGLPLPAINQVEFSAFNNRPTFLS 176
Query: 210 YVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIASKHKVTPQQVLLRWAT 269
Y N GI V A+S L L+ L + ++ K+ TP +LLR+
Sbjct: 177 YCFNHGILVQAFS--------PLTRGYRLSDIRLLD------LSLKYNKTPANILLRYCL 222
Query: 270 QNGIAIIPKSSKKERLLDNLR 290
Q G++ I K+S + +N++
Sbjct: 223 QKGVSPIFKASSFVHIHENVK 243
>At1g60680 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 340
Score = 77.4 bits (189), Expect = 3e-14
Identities = 86/337 (25%), Positives = 143/337 (41%), Gaps = 72/337 (21%)
Query: 11 NNGEKMPLVGLGCWKM--------PNDVCADQIYEAIKIGYRLFDGAQDYA---NEKEVG 59
+ G ++ GLGC + P ++ AI G FD + Y NE +G
Sbjct: 5 SQGLEVSAQGLGCMALSARYGAPKPETDAIALLHHAINSGVTFFDTSDMYGPETNELLLG 64
Query: 60 QGVNRAIKEGL---VKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFP 116
+ + +KE + K +V ++ P+ V A E +L L + +D++Y
Sbjct: 65 KALKDGVKEKVELATKFGFFIVEGEISEVRGDPEYVRAACEASLKRLDIACIDLYY---- 120
Query: 117 LAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFS 176
H + +VP+ T R L+KLV++GKIK +G+S S
Sbjct: 121 -------------------------QHRIDTRVPIEITMRELKKLVEEGKIKYIGLSEAS 155
Query: 177 GALIQDLLRGARIKPV-ALQIEHHPYL--TQERLIKYVKNAGIQVVAYS-------SFGP 226
+ I+ R + P+ A+QIE + +E +I + GI +VAYS + GP
Sbjct: 156 ASTIR---RAHAVHPITAVQIEWSLWSRDAEEDIIPICRELGIGIVAYSPLGRGFLAAGP 212
Query: 227 VSFLELEN---KKALNTPTLFEHDT----------IKSIASKHKVTPQQVLLRWATQNG- 272
LEN +KA T F+ + + ++A K TP Q+ L W G
Sbjct: 213 KLAENLENDDFRKATTTLPRFQQENVDHNKILFEKVSAMAEKKGCTPAQLALAWVHHQGD 272
Query: 273 -IAIIPKSSKKERLLDNLRINDALTLTDDELKQISGL 308
+ IP ++K E L N+R ++ LT +E+ ++ L
Sbjct: 273 DVCPIPGTTKIENLNQNIRAL-SVKLTPEEISELDSL 308
>CE06775 [R] KOG1577 Aldo/keto reductase family proteins
Length = 134
Score = 68.6 bits (166), Expect = 1e-11
Identities = 33/79 (41%), Positives = 46/79 (57%)
Query: 8 VTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIK 67
+TL+N MP VGLG W+ + + A+K GY L D A Y NE+ +G + I
Sbjct: 48 LTLSNAHSMPAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIA 107
Query: 68 EGLVKREDLVVVSKLWNSF 86
EG+VKREDL + +K+ N F
Sbjct: 108 EGVVKREDLFITTKVPNLF 126
>Hs22048214 [R] KOG1577 Aldo/keto reductase family proteins
Length = 159
Score = 66.6 bits (161), Expect = 5e-11
Identities = 33/97 (34%), Positives = 56/97 (57%), Gaps = 9/97 (9%)
Query: 34 QIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVKREDLVVVSKLWNSFHHPDNVP 93
Q+ +A+K+ + Y NE E+G + ++ +VKRE+L ++SKLW ++H V
Sbjct: 6 QVTKAVKVAIDI-----RYENENEIGVAIQEKLRGQMVKREELFIISKLWCTYHGKGLVK 60
Query: 94 RALERTLSDLQLDYVDIFYIHFPLAFK----PVPFDE 126
A ++ LSDL+ Y+D + +H+P +FK P DE
Sbjct: 61 GACQKMLSDLKQGYLDYYLVHWPASFKRGKESFPLDE 97
>Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins
Length = 594
Score = 65.1 bits (157), Expect = 1e-10
Identities = 43/135 (31%), Positives = 75/135 (54%), Gaps = 14/135 (10%)
Query: 158 LEKLVDQGKIKSLGISNFSGALIQDLL--RGARIKPVALQIEHHPYLTQERLIKYVKNAG 215
+++LVD+G +K++GIS F+ + ++ +L RG + +P+ +IE YLTQ++LI+Y ++ G
Sbjct: 1 MKELVDEGLVKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKG 60
Query: 216 IQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAI 275
I V AYS P+ L+ K L ++ E K I KH T Q + +
Sbjct: 61 IMVTAYS---PLDCLDRPWAK-LKDSSVLEDARSKVITVKHNKT--------TAQRNLVV 108
Query: 276 IPKSSKKERLLDNLR 290
PKS ++ + +N +
Sbjct: 109 NPKSVTQKCIAENFK 123
>Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins
Length = 156
Score = 65.1 bits (157), Expect = 1e-10
Identities = 43/135 (31%), Positives = 75/135 (54%), Gaps = 14/135 (10%)
Query: 158 LEKLVDQGKIKSLGISNFSGALIQDLL--RGARIKPVALQIEHHPYLTQERLIKYVKNAG 215
+++LVD+G +K++GIS F+ + ++ +L RG + +P+ +IE YLTQ++LI+Y ++ G
Sbjct: 1 MKELVDEGLVKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKG 60
Query: 216 IQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAI 275
I V AYS P+ L+ K L ++ E K I KH T Q + +
Sbjct: 61 IMVTAYS---PLDCLDRPWAK-LKDSSVLEDARSKVITVKHNKT--------TAQRNLVV 108
Query: 276 IPKSSKKERLLDNLR 290
PKS ++ + +N +
Sbjct: 109 NPKSVTQKCIAENFK 123
>At1g60690 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 345
Score = 65.1 bits (157), Expect = 1e-10
Identities = 79/339 (23%), Positives = 143/339 (41%), Gaps = 76/339 (22%)
Query: 11 NNGEKMPLVGLGCWKMPNDVCADQ--------IYEAIKIGYRLFDGAQDYANE-KEVGQG 61
+ G ++ GLGC + A + I+ AI G D + Y E E+ G
Sbjct: 14 SQGLEVSAQGLGCMGLTGHYGASKPETEAIALIHHAIHSGVTFLDTSDMYGPETNEILLG 73
Query: 62 VNRAIKEGLVKREDLVVVSKLWNSFHH--------PDNVPRALERTLSDLQLDYVDIFYI 113
+A+K+G+ RE + + +K S+ P V A E +L L + +D++Y
Sbjct: 74 --KALKDGV--REKVELATKFGISYAEGNREIKGDPAYVRAACEASLKRLDVTCIDLYY- 128
Query: 114 HFPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGIS 173
H + +VP+ T L+KL+++GKIK +G+S
Sbjct: 129 ----------------------------QHRIDTRVPIEITMGELKKLIEEGKIKYIGLS 160
Query: 174 NFSGALIQDLLRGARIKPV-ALQIEHHPYL--TQERLIKYVKNAGIQVVAYS-------S 223
S + I+ R + P+ A+Q+E + +E ++ + GI +V+YS +
Sbjct: 161 EASASTIR---RAHTVHPITAVQLEWSLWTRDVEEEIVPTCRELGIGIVSYSPLGRGFFA 217
Query: 224 FGPVSFLELENKKALNTPTLFE----------HDTIKSIASKHKVTPQQVLLRWATQNG- 272
GP L+N F+ ++ + +++ K TP Q+ L W G
Sbjct: 218 SGPKLVENLDNNDFRKALPRFQQENLDHNKILYEKVSAMSEKKGCTPAQLALAWVHHQGD 277
Query: 273 -IAIIPKSSKKERLLDNLRINDALTLTDDELKQISGLNQ 310
+ IP ++K E L N+R ++ LT +E+ ++ + Q
Sbjct: 278 DVCPIPGTTKIENLNQNIRAL-SVKLTPEEMSELETIAQ 315
>At1g60750 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 330
Score = 64.7 bits (156), Expect = 2e-10
Identities = 83/329 (25%), Positives = 139/329 (42%), Gaps = 72/329 (21%)
Query: 11 NNGEKMPLVGLGCWKM--------PNDVCADQIYEAIKIGYRLFDGAQDYANE-KEVGQG 61
+ G ++ GLGC + P + AI G D + Y E E+ G
Sbjct: 15 SQGLEVSAQGLGCMGLSDFYGAPTPETNAVALLRHAINAGVTFLDTSDIYGPETNELLLG 74
Query: 62 VNRAIKEGLVKREDLVVVSKLWNSFH-------HPDNVPRALERTLSDLQLDYVDIFYIH 114
+A+K+GL + +L + S P+ V A E +L L + +D++Y
Sbjct: 75 --KALKDGLRDKVELATKFGITASEDGKFGFRGDPEYVRIACEASLKRLGVTCIDLYY-- 130
Query: 115 FPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISN 174
H + +P+ T L+KLV++GKIK +G+S
Sbjct: 131 ---------------------------QHRIDTTLPIEITIGELKKLVEEGKIKYIGLSE 163
Query: 175 FSGALIQDLLRGARIKPV-ALQIEHHPYL--TQERLIKYVKNAGIQVVAYSSFGPVSFL- 230
S + I+ R + P+ A+QIE + +E +I + GI +VAYS G FL
Sbjct: 164 ASASTIR---RAHAVHPITAVQIEWSLWSRDVEEDIIPTCRELGIGIVAYSPLGR-GFLG 219
Query: 231 -------ELENKKALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNG--IAIIPKSSK 281
LEN K L ++ ++++A+K TP Q+ L W G + IP +SK
Sbjct: 220 LPRFQQENLENNKIL-------YEKVQAMATKKSCTPAQLALAWVHHQGDDVCPIPGTSK 272
Query: 282 KERLLDNLRINDALTLTDDELKQISGLNQ 310
+ L N+ ++ LT +E+ ++ + Q
Sbjct: 273 IQNLNQNIGAL-SVKLTPEEMVELEAIAQ 300
>At1g60730 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 342
Score = 62.4 bits (150), Expect = 9e-10
Identities = 83/337 (24%), Positives = 140/337 (40%), Gaps = 75/337 (22%)
Query: 11 NNGEKMPLVGLGCWKM--------PNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGV 62
+ G ++ GLGC + P I+ AI G D + Y E +
Sbjct: 14 SQGLEVSAQGLGCMGLSAFYGTPKPETEAIALIHHAIHSGVTFLDTSDIYGPETNELL-L 72
Query: 63 NRAIKEGLVKREDLVVVSKLWNSFHH--------PDNVPRALERTLSDLQLDYVDIFYIH 114
++A+K+G+ RE + + +K + P V A E +L + + +D++Y
Sbjct: 73 SKALKDGV--REKVELATKYGIRYAEGKVEFKGDPAYVRAACEASLMRVDVACIDLYY-- 128
Query: 115 FPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISN 174
H + +VP+ T L+KLV++GKIK +G+S
Sbjct: 129 ---------------------------QHRIDTRVPIEITIGELKKLVEEGKIKYIGLSE 161
Query: 175 FSGALIQDLLRGARIKPV-ALQIEHHPYL--TQERLIKYVKNAGIQVVAYS-------SF 224
S + I+ R + P+ ALQIE + +E +I + GI +VAYS +
Sbjct: 162 ASASTIR---RAHAVHPITALQIEWSLWSRDVEEDIIPTCRELGIGIVAYSPLGRGFFAS 218
Query: 225 GPVSFLELENKKAL---------NTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNG--I 273
GP L+N L + LFE + +++ K TP Q+ L W G +
Sbjct: 219 GPKLVENLDNNDTLPRFQQENLDHNKILFE--KVSAMSEKKGCTPAQLALAWVHHQGDDV 276
Query: 274 AIIPKSSKKERLLDNLRINDALTLTDDELKQISGLNQ 310
IP ++K E L N+ ++ LT +E+ ++ L Q
Sbjct: 277 CPIPGTTKIENLNQNIGAL-SVKLTPEEMSELESLAQ 312
>At1g10810 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 344
Score = 57.0 bits (136), Expect = 4e-08
Identities = 76/315 (24%), Positives = 128/315 (40%), Gaps = 69/315 (21%)
Query: 11 NNGEKMPLVGLGCW---------KMPNDVCADQIYEAIKIGYRLFDGAQDYA---NEKEV 58
+ G ++ GLGC K+ D+ A I+ AI G L D + Y NE +
Sbjct: 14 SQGLEVSAQGLGCMGLSIFDGTTKVETDLIA-LIHHAINSGITLLDTSDIYGPETNELLL 72
Query: 59 GQGVNRAIKEG--LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFP 116
GQ + ++E L + L++ + P V A E +L L + +D++Y
Sbjct: 73 GQALKDGMREKVELATKFGLLLKDQKLGYRGDPAYVRAACEASLRRLGVSCIDLYY---- 128
Query: 117 LAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISNFS 176
H + VP+ T L+KLV++GKIK +G+S
Sbjct: 129 -------------------------QHRIDTTVPIEVTIGELKKLVEEGKIKYIGLSEAC 163
Query: 177 GALIQDLLRGARIKPV-ALQIEHHPYL--TQERLIKYVKNAGIQVVAYS-------SFGP 226
+ I+ R + P+ A+Q+E + +E +I + GI +VAYS + GP
Sbjct: 164 ASTIR---RAHAVHPLTAVQLEWSLWSRDVEEDIIPTCRELGIGIVAYSPLGLGFFAAGP 220
Query: 227 VSFLELENKKALNTPTLFE----------HDTIKSIASKHKVTPQQVLLRWATQNG--IA 274
++N F+ ++ + ++A K TP Q+ L W G +
Sbjct: 221 KFIESMDNGDYRKGLPRFQQENLDHNKILYEKVNAMAEKKSCTPAQLALAWVHHQGNDVC 280
Query: 275 IIPKSSKKERLLDNL 289
IP +SK + L N+
Sbjct: 281 PIPGTSKIKNLNQNI 295
>At1g04690 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 328
Score = 51.2 bits (121), Expect = 2e-06
Identities = 64/303 (21%), Positives = 124/303 (40%), Gaps = 69/303 (22%)
Query: 42 GYRLFDGAQDYANEKEVGQGVNRAIKEGLVKREDLVVVSKLWNSFHHPDN-------VPR 94
G FD A+ YAN + + + +AI+E +R D+V+ +K++ P++ +
Sbjct: 44 GVNFFDNAEVYANGR-AEEIMGQAIRELGWRRSDIVISTKIFWGGPGPNDKGLSRKHIVE 102
Query: 95 ALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDT 154
+ +L L +DYVD+ Y H P + P+ +T
Sbjct: 103 GTKASLKRLDMDYVDVLYCHRP-----------------------------DASTPIEET 133
Query: 155 WRALEKLVDQGKIKSLGISNFSGALIQDLLRGA----RIKPVALQIEHHPYL---TQERL 207
RA+ ++D+G G S +S I + A + P+ Q E++ + +
Sbjct: 134 VRAMNYVIDKGWAFYWGTSEWSAQQITEAWGAADRLDLVGPIVEQPEYNMFARHKVETEF 193
Query: 208 IKYVKNAGIQVVAYSSF-----------GPV---SFLELENKKALNTPTLFEH-----DT 248
+ N GI + +S G + S LEN K L +L +
Sbjct: 194 LPLYTNHGIGLTTWSPLASGVLTGKYNKGAIPSDSRFALENYKNLANRSLVDDVLRKVSG 253
Query: 249 IKSIASKHKVTPQQVLLRWATQNG--IAIIPKSSKKERLLDNLRINDALTLTD----DEL 302
+K IA + VT Q+ + W N ++I ++++ ++ +N++ D + L D++
Sbjct: 254 LKPIADELGVTLAQLAIAWCASNPNVSSVITGATRESQIQENMKAVDVIPLLTPIVLDKI 313
Query: 303 KQI 305
+Q+
Sbjct: 314 EQV 316
>Hs17491434 [R] KOG1577 Aldo/keto reductase family proteins
Length = 117
Score = 50.8 bits (120), Expect = 3e-06
Identities = 28/78 (35%), Positives = 41/78 (51%), Gaps = 6/78 (7%)
Query: 10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69
LNNG K ++GLG WK P A+ + AI YR D + + N+ + +KE
Sbjct: 2 LNNGTKTDMLGLGTWKSPPGQVAEAVKVAINTVYRHIDCSHVHQNKDQ------EQLKEQ 55
Query: 70 LVKREDLVVVSKLWNSFH 87
+V+RE L ++SK W H
Sbjct: 56 VVRREWLFIISKPWGICH 73
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.138 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,846,708
Number of Sequences: 60738
Number of extensions: 923383
Number of successful extensions: 2566
Number of sequences better than 1.0e-05: 70
Number of HSP's better than 0.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2314
Number of HSP's gapped (non-prelim): 83
length of query: 329
length of database: 30,389,216
effective HSP length: 107
effective length of query: 222
effective length of database: 23,890,250
effective search space: 5303635500
effective search space used: 5303635500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)