ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5676 good DK KOG0973 Cell cycle control, cell division, chromosome partitioning Histone transcription regulator HIRA, WD repeat superfamily
r_klactV5676 good DK KOG0973 Transcription Histone transcription regulator HIRA, WD repeat superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5676 1951230 1948690 -847
(847 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR038c [DK] KOG0973 Histone transcription regulator HIRA WD rep... 713 0.0
SPBC15D4.03 [DK] KOG0973 Histone transcription regulator HIRA WD... 231 5e-60
SPBC31F10.13c [DK] KOG0973 Histone transcription regulator HIRA ... 149 2e-35
YBL008w [DK] KOG0973 Histone transcription regulator HIRA WD rep... 94 1e-18
HsM7219910 [DK] KOG0973 Histone transcription regulator HIRA WD ... 79 2e-14
Hs21536485 [DK] KOG0973 Histone transcription regulator HIRA WD ... 79 2e-14
7290824 [DK] KOG0973 Histone transcription regulator HIRA WD rep... 72 5e-12
At3g44530 [DK] KOG0973 Histone transcription regulator HIRA WD r... 67 9e-11
>YOR038c [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 875
Score = 713 bits (1840), Expect = 0.0
Identities = 388/884 (43%), Positives = 555/884 (61%), Gaps = 49/884 (5%)
Query: 1 MKLLKLPSKLHDGQLTQCEVDDNKLYIIG-GKYLSIWDSQTLLNAATGKTDVKEVKELEK 59
M+LLK P +H+ Q+ + + G G ++ W Q L++ A + +K++K
Sbjct: 1 MRLLKYPLDIHNEQVNALAALGPYIILAGSGGHVMAWRQQQLVDTAFDRVMIKDLKPEVS 60
Query: 60 MSLDLLESNQEDGRWLVVLDNQRLVYGSDHLL------ACLDLNK-DSNSEYKSREIGIF 112
+D + + + D + L GS+H L C D N +S + S+ +
Sbjct: 61 FQVD---QDTTGDIFFITGDLETLYIGSEHRLWGYSGWLCRDTNNINSVEKMNSKLLFEC 117
Query: 113 KDNEAITDLKYDKVNGLLFVSLSKANSLQIMDSKTWELKSSIELK--SKPISIITDPLGQ 170
K ITD+KYD G+LFV LS N + + KT++ S I + SKPI+ I DP GQ
Sbjct: 118 KSPSTITDVKYDINLGILFVLLSNENKILLFRHKTFDKLSEITIDKASKPITGIIDPTGQ 177
Query: 171 LLTVILQNRSVQIYQYDSHGTTKLHQSINQFVQTNPLPYRMTMSPQGDVIPMINSL---- 226
TV+ +RS+ +YQ + GT KL + Q VQ PL YR++MSPQ D++P+INS+
Sbjct: 178 TFTVMTSDRSILVYQINKTGTHKLINKLTQHVQMYPLHYRISMSPQADILPVINSVKGVP 237
Query: 227 HNNVPTAVLLDRIQKFKIKLSLVGYVAD-CKILKFSPRIYSKTKSPTSNDTQTFNLLASS 285
+N LLDR +K+ +LV ++ C++L +SP Y K T+ +NL+A+S
Sbjct: 238 NNATSCTALLDRNNNYKVTKTLVTPSSNGCRVLVYSPAFYEKPNLKKGTSTR-YNLIATS 296
Query: 286 GNEDGNVVVWNTNRIKPLFDASKVVNSYITDLEWDNSGLGLFAISQDGQLVIFAFQENEL 345
G+ DG ++VWNT R+KPLF+A +V ++ I D+ W G LFAIS D L FAFQE +L
Sbjct: 297 GSTDGTILVWNTKRMKPLFNALQVSSTAINDMSWSQDGFTLFAISNDATLYTFAFQEKDL 356
Query: 346 GDVMP---VEAVTEAAKEI-KLLDPL--------PFKPKAEEPDTKLP-PNKTAQQTTTN 392
G +P ++++ E K++ KL +PL P K EE + P PN +
Sbjct: 357 GVALPQTEIKSLQEVNKKLPKLEEPLAEQIPKSFPENIKLEESASAAPIPNDIGRSAVGK 416
Query: 393 SKKQPKAAE-----ITTISSTNMEFIQPSYMVPKDLKRKPVTEDPLLAQXXXXXXXXXXE 447
+ K A I TI ST+MEF PSY VP+DLKRKP P + E
Sbjct: 417 KPTKKKTANNQTNGIKTIQSTSMEFNTPSYTVPRDLKRKPKEATP--SNIAPGSKKQKKE 474
Query: 448 LDQIDFLDTNLFLPSVSFSKVRLAHPKIRASFQYS--SQGNFVLDIKNGLGNDQKPTSIT 505
L IDFLDT L LP+ SFS++RLA PKIR++F+YS + N +LD+KNG GN+Q+PT +
Sbjct: 475 LQPIDFLDTGLLLPNTSFSRIRLATPKIRSTFKYSPINNPNLILDVKNGSGNEQRPTIVK 534
Query: 506 LTRKDNESSKQLFQTFLPKFVTLCSAGSSFWAWSTDTGMIYVTSISGQMLFPPMLLGVPV 565
LT K + + LFQ F+PK +T+C+AG +FW++ ++ G IY+ S SG+ L P++LGV +
Sbjct: 535 LTSKVLDQDQVLFQDFIPKLITICTAGDTFWSFCSEDGSIYIYSDSGRKLMAPLVLGVSI 594
Query: 566 SFLEGSGDYLLCITSIGQMYCWNVNTGKIAFPINDVYSLLNPMLRYSDDVLSRAENITMC 625
SFLE G YLLC+TSIG++YCWN+ K+AFP N +Y LLNP LRYSDD+L+RAENIT+C
Sbjct: 595 SFLEACGTYLLCLTSIGELYCWNIEQKKLAFPTNTIYPLLNPSLRYSDDILTRAENITLC 654
Query: 626 AVTSQGIPIVTLSNGDGYMFDSAMEAWMLINDSWWPYGSQYWNFMSSAGVDLTSNDDEKK 685
++T +G+P+VTLSNGDGY+FD ME W+L++D WW YGSQYW+ ++ G+ S+
Sbjct: 655 SITKKGVPLVTLSNGDGYLFDKNMETWLLVSDGWWAYGSQYWDTTNTTGL---SSSKANT 711
Query: 686 DKYWNAEADI--LAKEVKNNKNSIINYLETKTNDELTRKGRMKHLQRFAKVLLMKEGFEN 743
D + +E++I + ++KN+ SIIN+LE KTNDEL RKGR+K+LQRFA+ +LMKEGFEN
Sbjct: 712 DSFNGSESNINEIVSDIKNDNQSIINFLECKTNDELNRKGRIKNLQRFARTILMKEGFEN 771
Query: 744 LEEMITLAHLENKILVSFRLKEVEEAIRLLKIYCIRIAEMGYTDRFSQTLSWLYDP---T 800
+EE++TL+HLENKIL+S RL+E EE +L+ +YCIR++E+GY DR + WLYD +
Sbjct: 772 MEEIVTLSHLENKILISIRLEEPEEFSKLMMVYCIRLSELGYMDRLNDVFQWLYDDLPIS 831
Query: 801 NTKFSPLDIDRRRNLIKDIIISCANIRQVQRVTTSYANELGVIS 844
T + D D +RNL+K I+I+C +IRQVQRVTT YA E+ +IS
Sbjct: 832 GTGSAFADKDFKRNLLKKILIACGDIRQVQRVTTRYAKEMNIIS 875
>SPBC15D4.03 [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 807
Score = 231 bits (588), Expect = 5e-60
Identities = 168/693 (24%), Positives = 316/693 (45%), Gaps = 102/693 (14%)
Query: 166 DPLGQLLTVILQNRSVQIYQYDSHGTTKLHQSINQFVQTNPLPYRMTMSPQGDVIPMINS 225
DP+GQ L + ++++++ + G K + + T R++ SP G I +N+
Sbjct: 193 DPMGQFLASQSFDHTLKVWKLSTFGVEKSIAKPFEQMPTGNRFLRLSWSPDGAHIASVNA 252
Query: 226 LHNNVPTAVLLDRIQKFKIKLSLVGYVADCKILKFSPRIYSKTKSPTSNDTQTFNLLASS 285
++ ++ R + ++LVG+ + F+P +Y D +++AS+
Sbjct: 253 VNEGAYVIAIVQR-DTWTYDINLVGHQGPLECATFNPYLYE--------DPFQKSIIASA 303
Query: 286 GNEDGNVVVWNTNRIKPLFDASKVVNSYITDLEWDNSGLGLFAISQDGQLVIFAFQENEL 345
+ DG V +WNT +P+ ++ S DL+W SG L+ +S DG L++ F+E+E
Sbjct: 304 AH-DGCVSIWNTACARPMAVIHELSCSSFVDLQWSTSGFELYGVSLDGNLMLLQFEESEF 362
Query: 346 GDVMPVEAVTEAAKEIKLLDPLPFKPKAEEPDTKLPPNKTAQQTTTNSKKQPKAAEITTI 405
G+ M I D L + + + N A +TT+ ++ QP++ + +
Sbjct: 363 GEKMDT---------IHYPDDLSYF-NSSRSKAHVNKNAAADRTTSPTQGQPESPSKSIL 412
Query: 406 SSTNMEFIQPSYMVPKDLKRKPVTEDPLLAQXXXXXXXXXXELDQIDFLDTNLFLPSVSF 465
+ +K V P+ P+ +
Sbjct: 413 LRPPPSIASSPESKRRKCPKKFVARPPVPH-------------------------PTSLY 447
Query: 466 SKVRLAHPKIRASFQYS-SQGNFVLDIKNGLGNDQKPTSITLTRKDNESSKQLFQTFLPK 524
S++R+ P ++ S S G ++ N L + + T + + + + ++LP
Sbjct: 448 SQIRIGCPYLKPKLVISKSFGTLIVKNHNQL------SLLKCTFSNLDGNDCSWFSYLPN 501
Query: 525 FVTLCSAGSSFWAWSTDTGMIYVTSISGQMLFPPMLLGVPVSFLEGSGDYLLCITSIGQM 584
+ L + S FWA +T+ IY+ S +G++L PP+++ FLE GD+L CI S G +
Sbjct: 502 AIVLANGTSVFWAVATEDSSIYIYSPAGRLLLPPVVVAATPCFLECCGDFLCCIVSTGLL 561
Query: 585 YCWNV-NTGKIAFPINDVYSLLNPMLR--YSDDVLSRAENITMCAVTSQGIPIVTLSNGD 641
Y WN+ N I P++ + P+ +S ++R +I VT QG P+ +S+G+
Sbjct: 562 YIWNIKNFEAIHSPVSTL-----PLFHSNFSVSKIARGPSIEQFFVTKQGHPVAIMSDGN 616
Query: 642 GYMFDSAMEAWMLINDSWWPYGSQYWNFMSSAGVDLTSNDDEKKDKYWNAEADILAKEVK 701
+ F +W+ +++ WW GSQYW ++S +
Sbjct: 617 AFAFIRDSSSWLRVSEGWWMIGSQYWGPLAS----------------------------E 648
Query: 702 NNKNSIINYLETKTNDELTRKGRMKHLQRFAKVLLMKEGFENLEEMITLAHLENKILVSF 761
+N+ S + +LE T++E+ + GR + LQR K L++++G++N E ++++ HLEN+++ S
Sbjct: 649 SNEESPLGFLERCTDEEIIKAGRGRFLQRLVKALMLRQGYDNYEMLVSIRHLENRLMSSA 708
Query: 762 RLKEVEEAIRLLKIYCIRIAEMGYTDRFSQTLSWLYDPTNTKFSPLDI------------ 809
+L + L +Y +IAE G D+ + L P + +D
Sbjct: 709 KLDLEYDFRENLILYAKKIAEEGMKDKMDELCKELLGPLRIPHNGIDTVKVGNRLWSPTI 768
Query: 810 --DRRRNLIKDIIISCANIRQVQRVTTSYANEL 840
+ +RNL+KDIII A R +QR+T+ Y++ L
Sbjct: 769 AGNNKRNLLKDIIIHTAKYRDMQRITSQYSDLL 801
>SPBC31F10.13c [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 932
Score = 149 bits (376), Expect = 2e-35
Identities = 102/373 (27%), Positives = 184/373 (48%), Gaps = 42/373 (11%)
Query: 456 TNLFLPSVSFSKVRLAHPKIRASFQYS--SQGNFVLDIKNGLGNDQKPTSITLTRKDNES 513
++L S S S + P+ + + +S ++ +VL++KNG +++ PT I N
Sbjct: 571 SSLIDSSTSISNINFEAPRYKTNIVHSLNNEQKYVLEVKNGT-SEKNPTRIVALENGNTK 629
Query: 514 SKQLFQTFLPKFVTLCSAGSSFWAWSTDTGMIYVTSISGQMLFPPMLLGVPVSFLEGSGD 573
+ +LP+ V L + FW+ + D G +++ S++G L PP+++ SFL +
Sbjct: 630 ----WMDYLPRPVILVTGSIHFWSIACDDGSLHLYSLTGSRLLPPIMIESKASFLHCNNA 685
Query: 574 YLLCITSIGQMYCWNVNTGKIAFPINDVYSLLNPMLRYSDDVL-----SRAENITMCAVT 628
YLLCI+S G +Y WNV F N + +L+ R S++V + ++ + +++
Sbjct: 686 YLLCISSSGMVYAWNVVNKTALFTANSLAPILS---RVSNNVTIENNSTDIPHVVIASIS 742
Query: 629 SQGIPIVTLSNGDGYMFDSAMEAWMLINDSWWPYGSQYWNFMSSAGVDLTSNDDEKKDKY 688
+G+P VTLS G+ Y++ S M W I + WW GS+ W+ S+G+ L SN
Sbjct: 743 KEGVPSVTLSTGETYVYSSTMLCWQRITEPWWAIGSREWD---SSGL-LQSN-------- 790
Query: 689 WNAEADILAKEVKNNKNSIINYLETKTNDELTRKGRMKHLQRFAKVLLMKEGFENLEEMI 748
++ + E +TN+ L GR K LQ+ + +EG+++ E ++
Sbjct: 791 ------------TQTESQPLKIYEHRTNNVLMDSGRGKLLQKMVADAITEEGYDDFETIV 838
Query: 749 TLAHLENKILVSFRLKEVEEAIRLLKIYCIRIAEMGYTDRFSQTLSWLYDPTNTKFSPLD 808
T+ HLENKI + LK +E + ++Y + G + + L L T TK S +
Sbjct: 839 TINHLENKIASARLLKLDDEFLVTSEVYVRLLMHHGLWQKLEEFLGEL--RTQTKCS-IK 895
Query: 809 IDRRRNLIKDIII 821
+ R + K +++
Sbjct: 896 LSGREVVAKMLVV 908
Score = 76.3 bits (186), Expect = 2e-13
Identities = 54/232 (23%), Positives = 110/232 (47%), Gaps = 15/232 (6%)
Query: 130 LFVSLSKANSLQIMDSKTWELKSSIELKSKPISIIT-DPLGQLLTVILQNRSVQIYQYDS 188
L VS+ +S+ + + T+E IE + IT DP G+ +R++++++
Sbjct: 148 LVVSVGLDSSIIVWNGTTFERLKRIEAHQSHVKGITFDPAGKYFATESDDRTIKVWRVSD 207
Query: 189 HGTTKLHQSINQFVQTNPLPY---RMTMSPQGDVIPMINSLHNNVPTAVLLDRIQKFKIK 245
K +I +PL R + SP G I N+++ V +++R + +
Sbjct: 208 FSIEK---TITGPFNNSPLSTYFRRPSWSPDGKHIAAPNAMNGPVSCVSIIER-GTWTSE 263
Query: 246 LSLVGYVADCKILKFSPRIYSKTKSPTSNDTQTFNLLASSGNEDGNVVVWNTNRIKPLFD 305
++L+G+ ++ F+P+++ ND + + G +D ++ +W++ +PL
Sbjct: 264 INLIGHEGPVEVTAFNPKLFRD-----KNDKLV--CILACGGQDRSLSIWSSALPRPLLS 316
Query: 306 ASKVVNSYITDLEWDNSGLGLFAISQDGQLVIFAFQENELGDVMPVEAVTEA 357
V I D+ W GL LF S DG +++ F++ E GD++ E +++A
Sbjct: 317 CQNVFQKSIGDVCWSPDGLSLFLCSYDGNVLVCTFEKEEFGDMVSDEEISKA 368
>YBL008w [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 840
Score = 93.6 bits (231), Expect = 1e-18
Identities = 88/400 (22%), Positives = 177/400 (44%), Gaps = 51/400 (12%)
Query: 1 MKLLKLPSKLHDGQLTQCEV------DDNKLYIIGGK--YLSIWDSQTLLNAATGKTDVK 52
MK++K P H + + E+ D K GG + IW ++L ++
Sbjct: 1 MKVVKFPWLAHREESRKYEIYTVDVSHDGKRLATGGLDGKIRIWSIDSILRCMELESLTP 60
Query: 53 EVKELEKMSLDLLESNQEDGRWLVVL---DNQRLVYGSDH---LLACLDLNKDSNSEYKS 106
E+ + + + L ++ G V D + L GSD L+ LD + S + S
Sbjct: 61 EIPLPQDLQMPLCSMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQSSQPAFGS 120
Query: 107 ---------REIGIFKDNEAITDLKYDKVNGLLFVSLSKANSLQIMDSKTWELKSSIELK 157
R+ + DN+ I D+ + + +L V++ S+ + + T+E ++
Sbjct: 121 EHEREHWTVRKRLVAHDND-IQDICWAPDSSIL-VTVGLDRSVIVWNGSTFEKLKRFDVH 178
Query: 158 SKPIS-IITDPLGQLLTVILQNRSVQIYQYDSHGTTK--LHQSINQFVQTNPLPY---RM 211
+ ++ DP + +R+++I++Y G + I + + +PL R
Sbjct: 179 QSLVKGVVFDPANKYFATTSDDRTMKIFRYHKTGDISFTIEHIITEPFKESPLTTYFRRP 238
Query: 212 TMSPQGDVIPMINSLHNNVPTAVLLDRIQKFKIKLSLVGYVADCKILKFSPRIYSKT--- 268
+ SP G I + N+ + V + +++R + +SL+G+ A ++ +F+PR++ +
Sbjct: 239 SWSPDGQHIAVPNATNGPVSSMAIVNR-GTWDTNVSLIGHDAPTEVARFNPRLFERNAGV 297
Query: 269 KSPTSNDTQT----------------FNLLASSGNEDGNVVVWNTNRIKPLFDASKVVNS 312
K +D + + + ++ +D ++ VW+T+R +P+ A + N
Sbjct: 298 KQKKDDDPENALVGQNDDKVHHFDKNIDSVVATAGQDKSLAVWSTSRPRPILVAFDIANK 357
Query: 313 YITDLEWDNSGLGLFAISQDGQLVIFAFQENELGDVMPVE 352
ITD+ W+ G LF S D + +F F+ NELG +P+E
Sbjct: 358 SITDMSWNPDGSLLFVASLDSSITLFKFENNELGKPIPLE 397
Score = 52.4 bits (124), Expect = 3e-06
Identities = 36/127 (28%), Positives = 60/127 (46%), Gaps = 9/127 (7%)
Query: 488 VLDIKNGLGNDQKPTSITLTRKDN-----ESSKQLFQTFLPKFVTLCSAGSS---FWAWS 539
VL+I+NG+ + S L + K+ +TF+P+ V +C+ GS W +
Sbjct: 664 VLEIRNGVERSIQFDSEALLDNPTRILGYQGGKRTIETFIPE-VIICAIGSKDCKCWCLA 722
Query: 540 TDTGMIYVTSISGQMLFPPMLLGVPVSFLEGSGDYLLCITSIGQMYCWNVNTGKIAFPIN 599
+ G IY+ S +GQ P + LG V + S YLL +T G + W++ K+
Sbjct: 723 SANGSIYILSYNGQQRIPKICLGHKVIKMVTSSKYLLVLTERGLFFAWDLLDLKLVLRNV 782
Query: 600 DVYSLLN 606
+ +LN
Sbjct: 783 PILPILN 789
>HsM7219910 [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 1017
Score = 79.3 bits (194), Expect = 2e-14
Identities = 49/189 (25%), Positives = 101/189 (52%), Gaps = 4/189 (2%)
Query: 166 DPLGQLLTVILQNRSVQIYQ-YDSHGTTKLHQSINQFVQTNPLPYRMTMSPQGDVIPMIN 224
DP+G+ + +RS+++++ D T + + ++ T + R++ SP G + +
Sbjct: 183 DPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHV-LRLSWSPDGHYLVSAH 241
Query: 225 SLHNNVPTAVLLDRIQKFKIKLSLVGYVADCKILKFSPRIYSKT-KSPTSNDTQTFNLLA 283
+++N+ PTA +++R + +K + VG+ ++KF+P+I+ K K+ +S
Sbjct: 242 AMNNSGPTAQIIER-EGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCC 300
Query: 284 SSGNEDGNVVVWNTNRIKPLFDASKVVNSYITDLEWDNSGLGLFAISQDGQLVIFAFQEN 343
+ G++D ++ VW T +PL ++ + I D+ W +GLG+ S DG + F ++
Sbjct: 301 AVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQD 360
Query: 344 ELGDVMPVE 352
ELGD + E
Sbjct: 361 ELGDPLSEE 369
Score = 75.9 bits (185), Expect = 2e-13
Identities = 104/522 (19%), Positives = 203/522 (37%), Gaps = 92/522 (17%)
Query: 366 PLPFKPKAEEPDTKLPPNKTAQQT-TTNSKKQPKAAEITTISSTNMEFIQPSYMV----P 420
P P +K+ P K T SK P A +T+++ T +E ++ +V P
Sbjct: 545 PAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSMTPTAVERLKEQNLVKELRP 604
Query: 421 KDLKRKPVTED---PLLAQXXXXXXXXXXELDQIDFL-------DTNLFLPSVSFS---- 466
+DL D PL E++ ++ D+ L S+S
Sbjct: 605 RDLLESSSDSDEKVPLAKASSLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAA 664
Query: 467 -----------------KVRLAHPKIRASFQYSSQGNFVLDIKNGLGNDQKPTSITLTR- 508
K+ + P+ + Q SS + ++++N + + L+R
Sbjct: 665 LTAEKEAMCLSAPALALKLPIPSPQRAFTLQVSSDPSMYIEVENEV---TVVGGVKLSRL 721
Query: 509 KDNESSKQLFQTFLPKFVTLCSAGSSFWAWSTDTGMIYVTSISGQMLFPPMLLGVPVSFL 568
K N K+ ++T L + + + + M+ V S G+ L P+LL P+S L
Sbjct: 722 KCNREGKE-WETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTL 780
Query: 569 EGSGDYLLCITSIGQMYCWNVNTGKIAFPINDVYSLLNPMLRYSDDVLSRAENITMCAVT 628
+G Y++ +T+ + W+V+ + ++S+L ++ +T
Sbjct: 781 HCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSIL----------AGSDMTVSQILLT 830
Query: 629 SQGIPIVTLSNGDGYMFDSAMEAWMLINDSWWPYGSQYWNFMSSAGVDLTSNDDEKKDKY 688
GIP++ LS+G Y F+ ++ W L++D +Q +F SS L S D
Sbjct: 831 QHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSL-AQCADFRSS----LPSQD------- 878
Query: 689 WNAEADILAKEVKNNKNSIINYLETKTNDELTRKGRMKHLQRFAKVLLMKEGFENLEEMI 748
A + + + N+ N + + R + H+ +++
Sbjct: 879 ----AMLCSGPLAINQGRTSN-----SGRQAARLFSVPHV---------------VQQET 914
Query: 749 TLAHLENKILVSFRLKEVEEAIRLLKIYCIRIAEMGYTDRFSQTLSWLYDP----TNTKF 804
TLA+LEN++ + L+ E L +Y + G+ R + L P T +++
Sbjct: 915 TLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQW 974
Query: 805 SPLDID-RRRNLIKDIIISCANIRQVQRVTTSYANELGVISD 845
+ R+R L+K+++ + QR+ T +L ++ D
Sbjct: 975 ESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRD 1016
>Hs21536485 [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 1017
Score = 79.3 bits (194), Expect = 2e-14
Identities = 49/189 (25%), Positives = 101/189 (52%), Gaps = 4/189 (2%)
Query: 166 DPLGQLLTVILQNRSVQIYQ-YDSHGTTKLHQSINQFVQTNPLPYRMTMSPQGDVIPMIN 224
DP+G+ + +RS+++++ D T + + ++ T + R++ SP G + +
Sbjct: 183 DPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHV-LRLSWSPDGHYLVSAH 241
Query: 225 SLHNNVPTAVLLDRIQKFKIKLSLVGYVADCKILKFSPRIYSKT-KSPTSNDTQTFNLLA 283
+++N+ PTA +++R + +K + VG+ ++KF+P+I+ K K+ +S
Sbjct: 242 AMNNSGPTAQIIER-EGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCC 300
Query: 284 SSGNEDGNVVVWNTNRIKPLFDASKVVNSYITDLEWDNSGLGLFAISQDGQLVIFAFQEN 343
+ G++D ++ VW T +PL ++ + I D+ W +GLG+ S DG + F ++
Sbjct: 301 AVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQD 360
Query: 344 ELGDVMPVE 352
ELGD + E
Sbjct: 361 ELGDPLSEE 369
Score = 76.3 bits (186), Expect = 2e-13
Identities = 103/522 (19%), Positives = 202/522 (37%), Gaps = 92/522 (17%)
Query: 366 PLPFKPKAEEPDTKLPPNKTAQQT-TTNSKKQPKAAEITTISSTNMEFIQPSYMV----P 420
P P +K+ P K T SK P A +T+++ T +E ++ +V P
Sbjct: 545 PAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSMTPTAVERLKEQNLVKELRP 604
Query: 421 KDLKRKPVTED---PLLAQXXXXXXXXXXELDQIDFL-------DTNLFLPSVSFS---- 466
+DL D PL E++ ++ D+ L S+S
Sbjct: 605 RDLLESSSDSDEKVPLAKASSLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAA 664
Query: 467 -----------------KVRLAHPKIRASFQYSSQGNFVLDIKNGLGNDQKPTSITLTR- 508
K+ + P+ + Q SS + ++++N + + L+R
Sbjct: 665 LTAEKEAMCLSAPALALKLPIPSPQRAFTLQVSSDPSMYIEVENEV---TVVGGVKLSRL 721
Query: 509 KDNESSKQLFQTFLPKFVTLCSAGSSFWAWSTDTGMIYVTSISGQMLFPPMLLGVPVSFL 568
K N K+ ++T L + + + + M+ V S G+ L P+LL P+S L
Sbjct: 722 KCNREGKE-WETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTL 780
Query: 569 EGSGDYLLCITSIGQMYCWNVNTGKIAFPINDVYSLLNPMLRYSDDVLSRAENITMCAVT 628
+G Y++ +T+ + W+V+ + ++S+L ++ +T
Sbjct: 781 HCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSIL----------AGSDMTVSQILLT 830
Query: 629 SQGIPIVTLSNGDGYMFDSAMEAWMLINDSWWPYGSQYWNFMSSAGVDLTSNDDEKKDKY 688
GIP++ LS+G Y F+ ++ W L++D +Q +F SS L S D
Sbjct: 831 QHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSL-AQCADFRSS----LPSQD------- 878
Query: 689 WNAEADILAKEVKNNKNSIINYLETKTNDELTRKGRMKHLQRFAKVLLMKEGFENLEEMI 748
+ + +II + + + R + H+ +++
Sbjct: 879 ---------AMLCSGPLAIIQGRTSNSGRQAARLFSVPHV---------------VQQET 914
Query: 749 TLAHLENKILVSFRLKEVEEAIRLLKIYCIRIAEMGYTDRFSQTLSWLYDP----TNTKF 804
TLA+LEN++ + L+ E L +Y + G+ R + L P T +++
Sbjct: 915 TLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQW 974
Query: 805 SPLDID-RRRNLIKDIIISCANIRQVQRVTTSYANELGVISD 845
+ R+R L+K+++ + QR+ T +L ++ D
Sbjct: 975 ESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRD 1016
>7290824 [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 1047
Score = 71.6 bits (174), Expect = 5e-12
Identities = 110/554 (19%), Positives = 209/554 (36%), Gaps = 75/554 (13%)
Query: 166 DPLGQLLTVILQNRSVQIYQYDSHGTTKLHQSINQFVQTNPLPY--RMTMSPQGDVIPMI 223
DPLG+ L +RS++I+ ++ + H F + + R++ SP G +
Sbjct: 181 DPLGRFLASQSDDRSIKIW--NTMNWSLSHTITEPFEECGGTTHILRLSWSPDGQYLVSA 238
Query: 224 NSLHNNVPTAVLLDRIQKFKIKLSLVGYVADCKILKFSPRIYSKTKSPTSNDTQTFNLLA 283
++++ PTA +++R + +K VG+ ++F I S+ ++ S
Sbjct: 239 HAMNGGGPTAQIIER-EGWKCDKDFVGHRKAVTCVRFHNSILSRQENDGSPSKPLQYCCL 297
Query: 284 SSGNEDGNVVVWNTNRIKPLFDASKVVNSYITDLEWDNSGLGLFAISQDGQLVIFAFQEN 343
+ G+ D ++ VW T +P+ ++ N+ I DL W L A S DG + F E
Sbjct: 298 AVGSRDRSLSVWMTALQRPMVVIHELFNASILDLTWGPQECLLMACSVDGSIACLKFTEE 357
Query: 344 ELGDVMPVEAVTEAAKEI---KLLDPL-PFKPKAEEPDTKL-----PPNKTAQQTTTNSK 394
ELG + E +++ ++ L P E P L P K +
Sbjct: 358 ELGKAISEEEQNAIIRKMYGKNYVNGLGKSAPVLEHPQRLLLPQGDKPTKFPLSNNNEAN 417
Query: 395 KQPKAAEITTISSTNMEFIQPSYMV-----PKDLKRKPVTEDPLLAQXXXXXXXXXXELD 449
++P + + T + I P ++ P L V+ L
Sbjct: 418 QRPISKQTETRTKDGKRRITPMFIPLHEDGPTSLSMNIVSSSGSSTTALTSCSAAIGTLP 477
Query: 450 ---QIDFLDTNLFLPSVSFSKVRLAHPKIRASFQYSSQGNFVLDIKNGLGNDQKPTSITL 506
+ T L SK+ L R Q +SQ L G N+ T
Sbjct: 478 AAAPTESAATPLMPLEPLVSKIDLGRLDSRLKTQPASQRRQSLPFDPGQSNELLRTP--- 534
Query: 507 TRKDNESSKQLFQTFLPKFVTLCSAGSSFWA--------------WSTDTGMI-YVTSIS 551
++++SS T P + + + G S + T GM+ VT+
Sbjct: 535 RLEEHQSS-----TCSPSNLNVTATGKSEFVKAALDYRLHVSNGHLKTQHGMLAKVTASD 589
Query: 552 GQMLFPPMLLGVPVSFLEGSGDYLLCITSIGQMYCWNVNTGKIAFPI-----NDVYSLLN 606
+ + +G P+ L Y + + G M ++ TG FP + V+ +
Sbjct: 590 SKEMLWEFYVGSPLVNLNLCEKYAMLCSLDGSMRLISMETGCPVFPAISLTSSAVHCAFS 649
Query: 607 P------------MLRYSD-------------DVLSRAENITMCAVTSQGIPIVTLSNGD 641
P +LR D ++L++ +VT+QG+P++ +G+
Sbjct: 650 PDNSLVGVLTECGLLRIWDIAKKVVSLAAGCLELLNKHGTAAQFSVTNQGMPLIGFPSGN 709
Query: 642 GYMFDSAMEAWMLI 655
Y + +++++W+++
Sbjct: 710 SYSYSTSLQSWLVL 723
>At3g44530 [DK] KOG0973 Histone transcription regulator HIRA WD repeat
superfamily
Length = 1051
Score = 67.4 bits (163), Expect = 9e-11
Identities = 55/248 (22%), Positives = 109/248 (43%), Gaps = 24/248 (9%)
Query: 118 ITDLKYDKVNGLLFVSLSKANSLQIMDSKTWELKSSIELKSKPISIIT-DPLGQLLTVIL 176
+ DL + + +L S S N++ I + +T + + + +T DP+G +
Sbjct: 121 VVDLNWSPDDSML-ASGSLDNTVHIWNMRTGMCTTVLRGHLSLVKGVTWDPIGSFIASQS 179
Query: 177 QNRSVQIYQYDSHGTTKLHQSINQFVQTNPLPY--RMTMSPQGDVIPMINSLHNNVPTAV 234
+++V I++ G H++ + ++ + R+ SP G + + +A
Sbjct: 180 DDKTVIIWRTSDWGMA--HRTDGHWAKSLGSTFFRRLGWSPCGHFLTTTHGFQKPKHSAP 237
Query: 235 LLDRIQKFKIKLSLVGYVADCKILKFSPRIYSKTKSPT----------------SNDTQT 278
+L+R ++ + +G+ A +++F+ ++ + S T D Q+
Sbjct: 238 VLER-GEWSVAYDFLGHSAPIIVVRFNHSMFKRIPSSTHETKQVGWSNGTSKSGEKDLQS 296
Query: 279 FNLLASSGNEDGNVVVWNTNRIKPLFDASKVVNSYITDLEWDNSGLGLFAISQDGQLVIF 338
+N++A G++D + VW T +PLF A + DL W G LFA S DG + +
Sbjct: 297 YNVIAM-GSQDRTITVWTTGSARPLFVAKHFFGQSVVDLSWSPDGYSLFACSLDGTVAMI 355
Query: 339 AFQENELG 346
F ELG
Sbjct: 356 HFDPKELG 363
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,019,811
Number of Sequences: 60738
Number of extensions: 2195134
Number of successful extensions: 7089
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 7042
Number of HSP's gapped (non-prelim): 25
length of query: 847
length of database: 30,389,216
effective HSP length: 115
effective length of query: 732
effective length of database: 23,404,346
effective search space: 17131981272
effective search space used: 17131981272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)