ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5780 check: MH L KOG0479 Replication, recombination and repair DNA replication licensing factor, MCM3 component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5780 1981275 1984067 931
(931 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YEL032w [L] KOG0479 DNA replication licensing factor MCM3 component 1089 0.0
SPCC1682.02c [L] KOG0479 DNA replication licensing factor MCM3 c... 698 0.0
At5g46280 [L] KOG0479 DNA replication licensing factor MCM3 comp... 560 e-159
Hs6631095 [L] KOG0479 DNA replication licensing factor MCM3 comp... 551 e-156
7290573 [L] KOG0479 DNA replication licensing factor MCM3 component 546 e-155
CE08392 [L] KOG0479 DNA replication licensing factor MCM3 component 489 e-138
ECU08g0290 [L] KOG0479 DNA replication licensing factor MCM3 com... 444 e-124
YLR274w [L] KOG0481 DNA replication licensing factor MCM5 component 323 8e-88
7299005 [L] KOG0477 DNA replication licensing factor MCM2 component 315 2e-85
At1g44900 [L] KOG0477 DNA replication licensing factor MCM2 comp... 313 6e-85
Hs20535929 [L] KOG0477 DNA replication licensing factor MCM2 com... 313 8e-85
At2g07690 [L] KOG0481 DNA replication licensing factor MCM5 comp... 311 3e-84
YBL023c [L] KOG0477 DNA replication licensing factor MCM2 component 306 7e-83
SPBC4.04c [L] KOG0477 DNA replication licensing factor MCM2 comp... 304 4e-82
YPR019w [L] KOG0478 DNA replication licensing factor MCM4 component 303 6e-82
CE03558 [L] KOG0481 DNA replication licensing factor MCM5 component 303 8e-82
SPAC3F10.01 [L] KOG0481 DNA replication licensing factor MCM5 co... 302 1e-81
SPBC25D12.03c [L] KOG0482 DNA replication licensing factor MCM7 ... 302 2e-81
At4g02060 [L] KOG0482 DNA replication licensing factor MCM7 comp... 301 2e-81
CE19038 [L] KOG0477 DNA replication licensing factor MCM2 component 300 5e-81
Hs14738665 [L] KOG0478 DNA replication licensing factor MCM4 com... 298 3e-80
Hs6981192 [L] KOG0481 DNA replication licensing factor MCM5 comp... 295 2e-79
Hs11418031 [L] KOG0481 DNA replication licensing factor MCM5 com... 294 4e-79
Hs21359886 [L] KOG0482 DNA replication licensing factor MCM7 com... 294 5e-79
CE21767 [L] KOG0478 DNA replication licensing factor MCM4 component 292 1e-78
7299365 [L] KOG0481 DNA replication licensing factor MCM5 component 292 1e-78
7295030 [L] KOG0482 DNA replication licensing factor MCM7 component 291 2e-78
Hs4758706 [L] KOG0477 DNA replication licensing factor MCM2 comp... 281 3e-75
ECU02g1150 [L] KOG0478 DNA replication licensing factor MCM4 com... 280 1e-74
At2g16440 [L] KOG0478 DNA replication licensing factor MCM4 comp... 280 1e-74
ECU05g0780 [L] KOG0480 DNA replication licensing factor MCM6 com... 273 1e-72
SPBC211.04c [L] KOG0480 DNA replication licensing factor MCM6 co... 272 2e-72
ECU04g0850 [L] KOG0477 DNA replication licensing factor MCM2 com... 272 2e-72
YGL201c [L] KOG0480 DNA replication licensing factor MCM6 component 268 2e-71
ECU06g0340 [L] KOG0481 DNA replication licensing factor MCM5 com... 268 4e-71
HsM14149623 [L] KOG0482 DNA replication licensing factor MCM7 co... 267 6e-71
CE09874 [L] KOG0482 DNA replication licensing factor MCM7 component 265 3e-70
CE00415 [L] KOG0480 DNA replication licensing factor MCM6 component 258 3e-68
YBR202w [L] KOG0482 DNA replication licensing factor MCM7 component 258 4e-68
ECU09g1360 [L] KOG0482 DNA replication licensing factor MCM7 com... 256 1e-67
7290738 [L] KOG0480 DNA replication licensing factor MCM6 component 252 2e-66
Hs7427519 [L] KOG0480 DNA replication licensing factor MCM6 comp... 248 2e-65
Hs19923727 [L] KOG0480 DNA replication licensing factor MCM6 com... 246 9e-65
7304207 [L] KOG0478 DNA replication licensing factor MCM4 component 244 3e-64
At3g09660 [L] KOG0480 DNA replication licensing factor MCM6 comp... 211 3e-54
ECU11g0800 [L] KOG0480 DNA replication licensing factor MCM6 com... 189 2e-47
At2g14050 [L] KOG0477 DNA replication licensing factor MCM2 comp... 137 8e-32
ECU07g0490 [L] KOG0478 DNA replication licensing factor MCM4 com... 135 2e-31
7300061 [L] KOG0478 DNA replication licensing factor MCM4 component 116 1e-25
SPCC16A11.17 [L] KOG0478 DNA replication licensing factor MCM4 c... 100 1e-20
Hs22056246 [L] KOG0477 DNA replication licensing factor MCM2 com... 67 2e-10
>YEL032w [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 971
Score = 1089 bits (2817), Expect = 0.0
Identities = 593/979 (60%), Positives = 692/979 (70%), Gaps = 82/979 (8%)
Query: 10 DAVFTDRMRRFQEFLDTHSHYTREIRSILEFNSNVVKEKKTDDD------YLNTADKDTM 63
DAVF DR+RRFQEFLDT + Y +RSI +NSN D D L D D +
Sbjct: 18 DAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDDADERDLLGDDDGDDL 77
Query: 64 DHDT--------NQLPLRITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALD 115
+ + N LP RI +SLDDLREFD++FW+G+L P++F+PPAE+A+++ A ++D
Sbjct: 78 EKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMD 137
Query: 116 DSPLGFRGFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKL 175
D P + W+LSFKGSFG ++LSPRTL + HLNKL+SVEGIVT+TSLVRPKL
Sbjct: 138 DVPHPNASAVSS-RHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKL 196
Query: 176 LRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRI 235
+RSVHYA TG HYRDY DA +PTPAIYP ED EGNKL TEYG+ ++DHQRI
Sbjct: 197 IRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRI 256
Query: 236 TVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKG 295
TVQEMPE AP GQLPRS KTKPGDR+N+VGV+KSLGAGG+ N
Sbjct: 257 TVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGM------NQSN 310
Query: 296 NGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPS 355
+ L GF+T+++GNTVYPLHARSTGV+A + L+D DIRNINKLS +IFD LSQSLAPS
Sbjct: 311 SNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPS 370
Query: 356 IYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAI 415
IYGH+HIKKAILLMLMGGVEKNL NGSHLRGDINILMVGDPSTAKSQ+LRFVLNTA+LAI
Sbjct: 371 IYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAI 430
Query: 416 ATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVM 475
ATTGRGSSGVGLTAAVTTD+ETGERRLEAGAMVLADRG+VCIDEFDKM+DVDRVAIHEVM
Sbjct: 431 ATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVM 490
Query: 476 EQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVT 535
EQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVN+DPH+NIALPDSLLSRFDLLFVVT
Sbjct: 491 EQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVT 550
Query: 536 DDINDIRDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXX---- 591
DDIN+IRDR+ISEHVLRTHRYLPPGYLEGEPVRE++NLSLAVG
Sbjct: 551 DDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGV 610
Query: 592 ---------VVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQ 642
VFEKFNPLL AGAKLAKN+G+ NG+E+P++V IPF+RKY+QYAKER+IPQ
Sbjct: 611 ENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQ 670
Query: 643 LTQEAVDVIIKSYSNLRNDQNTKKSPITARTLETLIRLSSAHAKVRLSKKVELEDAKVAT 702
LTQEA++VI+K+Y++LRND NTKKSPITARTLETLIRL++AHAKVRLSK V DAKVA
Sbjct: 671 LTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAA 730
Query: 703 QLLRFALLGED-GANFDEQ--EFAEG---------------------------RTTEXXX 732
LLRFALLGED G + DE+ E+ E ++T
Sbjct: 731 NLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSGSPIKSTPRRS 790
Query: 733 XXXXXXXXXXXXGAVYKEVDSEDAEEDQEMAETQPDPADGLESTMVRLAPXXXXXXXXXX 792
+ + D E + + P PAD RL
Sbjct: 791 TASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRL------------ 838
Query: 793 XXXXXVSPRRQLSVERRXXXXXXXXXXXXXXXXXXXTGPLETGSQLEPSHMTLDFMSIEE 852
VSPRR+ E G E + F ++E
Sbjct: 839 QLGLRVSPRRR---EHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVE- 894
Query: 853 MDQGSISTGRLSSLSGIVARLMQSDIFEEESYPVAALFERINEQVPEEEKFTVDEYVAGL 912
G+ISTGRLS +SGI+ARLMQ++IFEEESYPVA+LFERINE++PEEEKF+ EY+AGL
Sbjct: 895 --PGTISTGRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGL 952
Query: 913 RIMSDRNNLMVADGKVWRV 931
+IMSDRNNLMVAD KVWRV
Sbjct: 953 KIMSDRNNLMVADDKVWRV 971
>SPCC1682.02c [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 879
Score = 698 bits (1802), Expect = 0.0
Identities = 426/966 (44%), Positives = 564/966 (58%), Gaps = 135/966 (13%)
Query: 9 SDAVFTDRMRRFQEFLDTHSHYTREIRSILEFNSNVVKEKKTDDDYLNTADKDTMDHDTN 68
+D VF DR+R FQE+L E TDD + T ++ + N
Sbjct: 6 ADEVFKDRVRIFQEYL----------------------EHDTDDANV-TLYQEAILRMLN 42
Query: 69 QLPLRITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDP 128
R+ V++D+LR++++ G+L P ++ P + A+ L D P+ + ++
Sbjct: 43 MGQRRLIVNIDELRDYNRELADGVLLKPLEYVEPFDEALRNVVSTLID-PVVHKDLKD-- 99
Query: 129 SRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHH 188
+ + + F+GSFG + ++PRTL + HLNK+IS+EGIVTR S VRPK+++SVHY + T H
Sbjct: 100 -KLFYVGFRGSFGDHHVNPRTLRAMHLNKMISLEGIVTRCSFVRPKVIKSVHYCEATKRH 158
Query: 189 HYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQ 248
H++ Y DA S + +YP +D+ GN L E+GF + DHQ I++QEMPE+APPGQ
Sbjct: 159 HFKQYADATMNGGLSFQS-TVYPTQDENGNPLSIEFGFSTFRDHQSISLQEMPERAPPGQ 217
Query: 249 LPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIG 308
LPRS KPGDR+NIVG Y+S+G+ T G+ + + FRTV++
Sbjct: 218 LPRSIDILLDDDLVDTVKPGDRVNIVGQYRSMGSK--TSGNTS--------ATFRTVLLA 267
Query: 309 NTVYPLHAR----STGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKK 364
N V L + + G A++ ++D DIRNINKL+ N+F+ LS SLAPSIYG+E++K+
Sbjct: 268 NNVVLLGNKPGLGNVGGGALD-ITDADIRNINKLARKKNVFELLSTSLAPSIYGYEYVKQ 326
Query: 365 AILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSG 424
AILL+L+GG EKNL NG+H+RGDINILMVGDPSTAKSQ+LRFVLNTA LAIATTGRGSSG
Sbjct: 327 AILLLLLGGTEKNLTNGTHIRGDINILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSG 386
Query: 425 VGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAK 484
VGLTAAVTTDKETGERRLEAGAMVLADRG+VCIDEFDKMSD+DRVAIHEVMEQQTVTIAK
Sbjct: 387 VGLTAAVTTDKETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAK 446
Query: 485 AGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDR 544
AGIHT+LNARCSVIAAANP++GQYD+ KDPH+NIALPDS+LSRFDLLF+VTDDI+D +DR
Sbjct: 447 AGIHTSLNARCSVIAAANPIYGQYDIRKDPHQNIALPDSMLSRFDLLFIVTDDIDDKKDR 506
Query: 545 AISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXX-----XXXXVVFEKFNP 599
A+SEHVLR HRYLPPG G PVR+ +N L VG V+E F+
Sbjct: 507 ALSEHVLRMHRYLPPGVEPGTPVRDSLNSVLNVGATNAAGVSTENVEQEVETPVWETFSS 566
Query: 600 LLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLR 659
LLHA A+ K +++ I F+RKYIQYAK RI P L Q + I Y LR
Sbjct: 567 LLHANARTKKK----------ELLNINFVRKYIQYAKSRIHPILNQATAEYITNIYCGLR 616
Query: 660 ND----QNTKKSPITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALLGE--- 712
ND + SP+TARTLETLIRLS+AHAK RLS VE++DAK A ++LR+AL E
Sbjct: 617 NDDLQGNQRRTSPLTARTLETLIRLSTAHAKARLSSVVEVKDAKAAEKILRYALFREVVK 676
Query: 713 -DGANFDEQEFAEGRTTEXXXXXXXXXXXXXXXGAVYKEVDSEDAEEDQ---EMAETQPD 768
+Q G +E DSED D E +E + D
Sbjct: 677 PKRKKHKKQRLEAG-----------------------EEFDSEDDNSDDMDIEESEEEMD 713
Query: 769 PADGLESTMVRLAPXXXXXXXXXXXXXXXVSPRRQLSVERRXXXXXXXXXXXXXXXXXXX 828
++S R+ R Q + +
Sbjct: 714 TNMVIDSGSRRVT-------------------RSQNATSQSQESGSEIGSSIAGTAGSYN 754
Query: 829 TGPLETGSQLEPSHMTLDFMSIE-EMDQGSISTG----------------------RLSS 865
G T +H TL S E +I+TG ++S
Sbjct: 755 VGTSNTQLSWPSTHSTLPATSRELASSDRNINTGTSVASEVSASVSEQSTVSLPREKMSV 814
Query: 866 LSGIVARLMQSDIFEEESYPVAALFERINEQVPEEEKFTVDEYVAGLRIMSDRNNLMVAD 925
+A L +S++F EE + + E IN + ++ F+ +E + L+ M +N +M +D
Sbjct: 815 FMARLASLTKSELFSEECASLEDVLESIN-NIEDDVGFSREEAIVALKEMDAQNKIMFSD 873
Query: 926 GKVWRV 931
V+R+
Sbjct: 874 NVVYRI 879
>At5g46280 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 776
Score = 560 bits (1442), Expect = e-159
Identities = 318/692 (45%), Positives = 435/692 (61%), Gaps = 63/692 (9%)
Query: 45 VKEKKTDDDYLNTADKDTMDHDTNQLPLRITVSLDDLREFDKTFWTGLLQVPSFFLPPAE 104
++ K+ +L++ + + +Q R+ +++ D+ + + +L+ P+ ++
Sbjct: 9 LRHKRDFIQFLDSMYMEEIKALVHQKRHRLIINISDIHHHFREVASRILKNPNEYMQSFC 68
Query: 105 RAVSETAMALDDSPLGFRGFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGI 164
A +E A+D L + F+G F ++PR L S + ++ VEGI
Sbjct: 69 DAATEATRAIDPKYL-------KEGELVLVGFEGYFVSRVVTPRELLSDFIGSMVCVEGI 121
Query: 165 VTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEY 224
VT+ SLVRPK+++SVH+ +TG RDYRD +PT ++YP D +GN LVTEY
Sbjct: 122 VTKCSLVRPKVVKSVHFCPSTGEFTNRDYRDITSHA--GLPTGSVYPTRDDKGNLLVTEY 179
Query: 225 GFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGG 284
G C Y DHQ +++QE+PE A PGQLPRS KPGDR+++ G+YK+L
Sbjct: 180 GLCKYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALPG-- 237
Query: 285 LTGGSNNNDKGNGALSG-FRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDN 343
K G+++G FRT++I N + L+ + + D+ NI ++ D+
Sbjct: 238 ---------KSKGSVNGVFRTILIANNIALLNKEANA----PIYTKQDLDNIKNIARRDD 284
Query: 344 IFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQM 403
FD L++SLAPSIYGH IKKA++L+++GGVEKNL NG+HLRGDIN++MVGDPS AKSQ+
Sbjct: 285 AFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQL 344
Query: 404 LRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKM 463
LR ++N A LAI+TTGRGSSGVGLTAAVT+D+ETGERRLEAGAMVLAD+GIVCIDEFDKM
Sbjct: 345 LRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKM 404
Query: 464 SDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDS 523
+D DRVAIHEVMEQQTVTIAKAGIH +LNARCSV+AAANP++G YD + P KNI LPDS
Sbjct: 405 NDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDS 464
Query: 524 LLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYL-------PPGYLEGEPVREQINLSLA 576
LLSRFDLLF+V D ++ D ISEHVLR HRY P G L P + N
Sbjct: 465 LLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYKNDRGEAGPDGSL---PYAREDN---- 517
Query: 577 VGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAK 636
+F K+N LH K RG ++ L I F++KYI YAK
Sbjct: 518 ------------AESEMFVKYNQTLHG----KKKRGQTHDKTL----TIKFLKKYIHYAK 557
Query: 637 ERIIPQLTQEAVDVIIKSYSNLRNDQNTKKS----PITARTLETLIRLSSAHAKVRLSKK 692
RI P+LT EA + I ++Y++LRN + K+ PITARTLET+IRL++AHAK++LS +
Sbjct: 558 HRITPKLTDEASERIAEAYADLRNAGSDTKTGGTLPITARTLETIIRLATAHAKMKLSSE 617
Query: 693 VELEDAKVATQLLRFALLGEDGANFDEQEFAE 724
V DA+ A +L+ FA+ ++ D++E E
Sbjct: 618 VTKADAEAALKLMNFAIYHQELTEMDDREQEE 649
>Hs6631095 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 808
Score = 551 bits (1419), Expect = e-156
Identities = 332/725 (45%), Positives = 433/725 (58%), Gaps = 61/725 (8%)
Query: 73 RITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQW 132
R+ V+++DLR ++ LL L +RA+ + ++D + ++
Sbjct: 46 RLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDAT-------YAKQYEEF 98
Query: 133 RLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRD 192
+ +GSFG +SPRTL S L+ ++ VEGIVT+ SLVRPK++RSVHY T R
Sbjct: 99 YVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR 158
Query: 193 YRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRS 252
Y D + P+ ++YP +D+E N L TEYG Y DHQ IT+QEMPEKAP GQLPRS
Sbjct: 159 YSDLTTLV--AFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRS 216
Query: 253 XXXXXXXXXXXKTKPGDRINIVGVYKSLGA--GGLTGGSNNNDKGNGALSGFRTVVIGNT 310
K KPGDR+ +VG Y+ L GG T G+ FRTV+I
Sbjct: 217 VDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGT------------FRTVLIACN 264
Query: 311 VYPLHARSTGVSAVETLSDNDIRNINKLSM--HDNIFDTLSQSLAPSIYGHEHIKKAILL 368
V + A + S DI I K S +IFD L++SLAPSI+GH+++KKAIL
Sbjct: 265 V-----KQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILC 319
Query: 369 MLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLT 428
+L+GGVE++L NGSH+RGDINIL++GDPS AKSQ+LR+VL TA AI TTGRGSSGVGLT
Sbjct: 320 LLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLT 379
Query: 429 AAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIH 488
AAVTTD+ETGERRLEAGAMVLADRG+VCIDEFDKMSD+DR AIHEVMEQ VTIAKAGIH
Sbjct: 380 AAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH 439
Query: 489 TTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISE 548
LNARCSV+AAANPV+G+YD K P +NI L DSLLSRFDLLF++ D ++ +DR IS+
Sbjct: 440 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISD 499
Query: 549 HVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLA 608
HVLR HRY PG +G+ + + + ++EK + LLH G K
Sbjct: 500 HVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLH-GTKKK 558
Query: 609 KNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQN----- 663
K + +V+ F++KYI AK I P LTQE+ I + YS LR+ +
Sbjct: 559 KEK----------MVSAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDT 607
Query: 664 TKKSPITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALL------------- 710
+ SP+TARTLETLIRL++AHAK R+SK V+L+DA+ A +L+++A
Sbjct: 608 ARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKR 667
Query: 711 GEDGANFDEQEFAEGRTTEXXXXXXXXXXXXXXXGAVYKEVDSEDAEEDQEMAETQPDPA 770
ED + +++E E G Y D D EE+ T P A
Sbjct: 668 SEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHT-PKTA 726
Query: 771 DGLES 775
D E+
Sbjct: 727 DSQET 731
>7290573 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 819
Score = 546 bits (1408), Expect = e-155
Identities = 315/643 (48%), Positives = 413/643 (63%), Gaps = 46/643 (7%)
Query: 73 RITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQW 132
R+ V+++DL+ + GLL + RA+ E A +D G+ D
Sbjct: 43 RLIVNVNDLKRKNPQRALGLLSNAADEQLAFGRALKEYASTVDP---GYAKMHEDLF--- 96
Query: 133 RLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRD 192
+ F+G FG ++PR+L S +L ++ VEGIVT+ SL+RPK++RSVHY T R
Sbjct: 97 -VGFEGCFGNRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERK 155
Query: 193 YRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRS 252
Y D +VP+ A YP +D++GN L TEYG Y DHQ +T+QEMPEKAP GQLPRS
Sbjct: 156 YTDLTSFE--AVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRS 213
Query: 253 XXXXXXXXXXXKTKPGDRINIVGVYKSLGA--GGLTGGSNNNDKGNGALSGFRTVVIGNT 310
+ KPGDR+ IVG Y+ L GG T G+ FRTV++ N
Sbjct: 214 VDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGT------------FRTVLLANN 261
Query: 311 VYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLML 370
+ L S +S DI KL+ +++IF+ LS+SLAPSI+GH ++K+AIL +L
Sbjct: 262 ISLLSKESN-----LDISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLL 316
Query: 371 MGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAA 430
+GGVEK LPNG+ LRGDIN+L++GDPS AKSQ+LR+VLNTA AI TTGRGSSGVGLTAA
Sbjct: 317 LGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAA 376
Query: 431 VTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTT 490
VTTD+ETGERRLEAGAMVLADRG+VCIDEFDKMSD+DR AIHEVMEQ VTI+KAGIH +
Sbjct: 377 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAS 436
Query: 491 LNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHV 550
LNARCSV+AAANPV+G+YD K P +NI L DSLLSRFDLLFV+ D I+ D+ IS+HV
Sbjct: 437 LNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHV 496
Query: 551 LRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKN 610
+R HRY P +GEP+ + S A V+EK++ LLH ++
Sbjct: 497 VRMHRYRNPKEADGEPL--SMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSRQRHE 554
Query: 611 RGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQN-----TK 665
+ I+++ F+RKYI AK + P+L ++A + I YS LR+ + +
Sbjct: 555 K----------ILSVEFMRKYIHIAK-CMKPKLGEQACEAIANEYSRLRSQEAVETDVAR 603
Query: 666 KSPITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFA 708
PITARTLETLIRLS+AHA+ R+SK V ++DA A +L++FA
Sbjct: 604 TQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
>CE08392 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 812
Score = 489 bits (1260), Expect = e-138
Identities = 307/756 (40%), Positives = 418/756 (54%), Gaps = 78/756 (10%)
Query: 46 KEKKTDDDYLNTADK--DTMDHDTNQLPL------RITVSLDDLREFDKTFWTGLLQVPS 97
++++ + YLN D DT + + + R+ ++LD++RE GLL
Sbjct: 17 RKQEITEQYLNFLDNQADTFHYRQKIVKMMNDGESRLVMNLDEIREILPERAEGLLTQSV 76
Query: 98 FFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNK 157
+ + A+ D + GF + F+G+FG ++PRTL S++L
Sbjct: 77 LEMNCLQSALQMAINRSDVQAVVKTGFH--------VGFEGTFGERHVNPRTLKSSYLGN 128
Query: 158 LISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEEDQEG 217
L+ EGIVT+ S VR KLL SVHY T + + D + T YP ED+
Sbjct: 129 LVCCEGIVTKCSTVRQKLLTSVHYCPATNKVLEKKFAD--FTMLDTAVTNNNYPTEDENK 186
Query: 218 NKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVY 277
N L TE+G Y DHQ T+QE+PE AP GQLPR+ + KPGDR+ I+GV+
Sbjct: 187 NPLETEFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRVKPGDRVRIIGVF 246
Query: 278 KSLGAGGLTGGSNNNDKGNGALSG-FRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNIN 336
+ L +K NG SG FR+++I N H + + D++++
Sbjct: 247 RVLP-----------NKQNGVSSGSFRSIIIIN-----HIQMLSKEVIPNFEPQDVKDVR 290
Query: 337 KLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDP 396
K+S N F+ L++SLAPSI GHE KKA+L +L+GG+EK L NGS LRGDIN+L++GDP
Sbjct: 291 KISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDP 350
Query: 397 STAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVC 456
S AKSQ+LR+VL A AI TTGRGSSGVGLTAAVTTD ++GERRLEAGAMVLADRG+VC
Sbjct: 351 SVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTDPDSGERRLEAGAMVLADRGVVC 410
Query: 457 IDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHK 516
IDEFDKMSD+DR AIHEVMEQ VTI+KAGIH LNARCSV+AAANPV+G+Y+ K P +
Sbjct: 411 IDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPFKSPME 470
Query: 517 NIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLA 576
NI + DSLLSRFDL+FV+ D+ + +D ++EHVL+ H Y G +G L +
Sbjct: 471 NIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYRTQGEADGTV------LPMG 524
Query: 577 VGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAK 636
G A + + + G + +I+ + F+RKYI A+
Sbjct: 525 GGVETISTINMETK-----------KASSSIYEENTQWAGIQDTKILTMDFMRKYIHLAR 573
Query: 637 ERIIPQLTQEAVDVIIKSYSNLRNDQNTKKS-----PITARTLETLIRLSSAHAKVRLSK 691
+ P+LT EA + I + Y+++R+ TK P+TAR LETLIRLS+A AK R SK
Sbjct: 574 S-VQPKLTDEATEYISEVYADIRSFDITKTDQERTMPVTARQLETLIRLSTAIAKARFSK 632
Query: 692 KVELEDAKVATQLLRFALLGE-----------------DGANFDEQEFAEGRTTEXXXXX 734
KVE ED + A LL FA E DG + ++Q E T
Sbjct: 633 KVEREDTEKAYNLLHFACFKEKPKARQEYEKKKRAPRIDGDDDEDQSDNEDMATSEEPQS 692
Query: 735 XXXXXXXXXXGAVYKEV---DSEDAEEDQEMAETQP 767
V + DS+D+ D + E+QP
Sbjct: 693 SSVPTAATPRRGVRRRAEDDDSQDSMMDTTIGESQP 728
>ECU08g0290 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 687
Score = 444 bits (1142), Expect = e-124
Identities = 256/526 (48%), Positives = 333/526 (62%), Gaps = 50/526 (9%)
Query: 52 DDYLNTADKDTMDHDTNQLPL----RITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAV 107
+ Y DKD + + +LP RI ++++D+R FDK G+L+ P+ +P E +
Sbjct: 14 ESYRTPQDKDIAE-EIAKLPYEDHQRIVLNVNDMRLFDKGLARGVLEDPATLVPFIEDEL 72
Query: 108 SETAMALDDSPLGFRGFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTR 167
S+ R+ L KGSFG L+PRTL+S ++ K++ VEGIVT
Sbjct: 73 SDIG-----------------GRKIFLGIKGSFGNYFLNPRTLSSVYIGKMVCVEGIVTS 115
Query: 168 TSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFC 227
S+ RPK+++SVHY + + ++YRDA V T ++YP D +G L TE+G
Sbjct: 116 CSICRPKVMKSVHYNPSKNVFYSKEYRDATMVTKLPV-TNSVYPTRDVDGTLLTTEFGLS 174
Query: 228 HYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTG 287
Y D+Q + +QEMPEKAPPGQLPRS KPGDR I G+YKSL G
Sbjct: 175 EYFDYQTVVLQEMPEKAPPGQLPRSVEVILSFDLVDGLKPGDRAKIYGIYKSLCFGNQQF 234
Query: 288 GSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVS-AVETLSDNDIRNINKLSMHDNIFD 346
S FRTVVI N + V VE + ++N++ L
Sbjct: 235 PSR-----------FRTVVIANNIEKAEEEEVEVEPGVEFERLSQMKNMHHL-------- 275
Query: 347 TLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRF 406
+APSI+GH+ +K++I L+L+GG E + NGS +RGDINIL+VGDPSTAKSQ+LR+
Sbjct: 276 -----IAPSIFGHDIVKRSIALLLVGGNEVVMRNGSKIRGDINILLVGDPSTAKSQLLRY 330
Query: 407 VLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDV 466
VLN A L+IATTG+GSSGVGLTAAV DK+TGE+RLEAGAMVLADRG+VCIDEFDKMSD
Sbjct: 331 VLNAAQLSIATTGKGSSGVGLTAAVVLDKDTGEKRLEAGAMVLADRGVVCIDEFDKMSDG 390
Query: 467 DRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLS 526
DRVAIHEVMEQQTVTIAKAGIHTTLNARCSV+AAANP++GQY ++ P N+ LP+SLL+
Sbjct: 391 DRVAIHEVMEQQTVTIAKAGIHTTLNARCSVLAAANPIWGQYKESRPPQDNVRLPESLLT 450
Query: 527 RFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGY-LEGEPVREQI 571
RFDL+FV D N D+ +S HVLR H L GY EG V++++
Sbjct: 451 RFDLIFVTLDKSNTDIDQLVSGHVLRMH-MLTQGYEEEGMGVKQEV 495
Score = 62.8 bits (151), Expect = 2e-09
Identities = 35/83 (42%), Positives = 58/83 (69%), Gaps = 3/83 (3%)
Query: 629 RKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQNTKKS--PITARTLETLIRLSSAHAK 686
R YI+Y +++ P L++EA +I + Y++LR ++ K+ IT R LET+IRL++A+AK
Sbjct: 497 RAYIRYCRQKK-PVLSREAAGLIAREYTSLRQSKDRKEQIVSITPRMLETMIRLATANAK 555
Query: 687 VRLSKKVELEDAKVATQLLRFAL 709
+RLS VE +DA+ A L++ +L
Sbjct: 556 LRLSDVVEYDDAECAVNLVKDSL 578
>YLR274w [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 775
Score = 323 bits (828), Expect = 8e-88
Identities = 220/725 (30%), Positives = 361/725 (49%), Gaps = 99/725 (13%)
Query: 37 ILEFNSNVVKEKKTDDDYLNTADKDTMDHDTNQLPLRITVSLDDLREFDKTFWTGLLQVP 96
I++ N + E + D ++ +D + ++ +TV+++ L +++ + L P
Sbjct: 27 IIKSFKNFILEFRLDSQFIY---RDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEP 83
Query: 97 SFFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQWRLSFKGSFGPNSLSP--------- 147
S +P E A+++ A + ND + S NSL
Sbjct: 84 SDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNA 143
Query: 148 -----RTLNSTHLNKLISVEGIVTRTSLVRPK------LLRSVHYAQTTGHHHYRDYRD- 195
R L+S H++K++ + GI+ TS++ + + R+ + + +++
Sbjct: 144 NQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGN 203
Query: 196 ---------AXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCH----YMDHQRITVQEMPE 242
+ S+ + +E + N Y H ++D Q + +QE+PE
Sbjct: 204 TVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPE 263
Query: 243 KAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGF 302
P G++PR+ K PG R+ IVG+Y + G + G+
Sbjct: 264 LVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAI 323
Query: 303 RTVVIGNTVYPLHARSTGV-SAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEH 361
RT I ++ + ++V ++ + +LS + +++ L+ S+APSI+G+E
Sbjct: 324 RTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNED 383
Query: 362 IKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRG 421
IKKAI+ +LMGG +K LP+G LRGDIN+L++GDP TAKSQ+L+FV + +A+ T+G+G
Sbjct: 384 IKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKG 443
Query: 422 SSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVT 481
SS GLTA+V D T E LE GAMVLAD G+VCIDEFDKM D DRVAIHE MEQQT++
Sbjct: 444 SSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTIS 503
Query: 482 IAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDI 541
IAKAGI T LN+R SV+AAANP++G+YD K P NI ++LSRFD++F+V DD N+
Sbjct: 504 IAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEE 563
Query: 542 RDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLL 601
RD +I+ HV+ H
Sbjct: 564 RDISIANHVINIHT---------------------------------------------- 577
Query: 602 HAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND 661
A +N+ + NGSE ++I +++YI Y + + P+L+ +A + + ++ +R
Sbjct: 578 -GNANAMQNQQEENGSE----ISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQ 632
Query: 662 ------QNTKKS--PITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALLGED 713
++T++S PIT R LE +IR++ + AK+ LS + A +L + + + D
Sbjct: 633 LLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTM--D 690
Query: 714 GANFD 718
A+ D
Sbjct: 691 AASQD 695
>7299005 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 887
Score = 315 bits (808), Expect = 2e-85
Identities = 205/559 (36%), Positives = 298/559 (52%), Gaps = 64/559 (11%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
RT HLN+L+ G+VT T+ V P+L + G+ + P
Sbjct: 280 RTFRKLHLNQLVRTLGVVTATTGVLPQLSVIKYDCVKCGY-----VLGPFVQSQNTEIKP 334
Query: 208 AIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKP 267
PE G + Y ++Q+IT+QE P + P G++PRS + KP
Sbjct: 335 GSCPECQSTGPFSINMEQTL-YRNYQKITLQESPGRIPAGRIPRSKDVILLADLCDQCKP 393
Query: 268 GDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETL 327
GD + + G+Y + G L N D+G F TV+I N V ++ V++L
Sbjct: 394 GDELEVTGIYTNNYDGSL-----NTDQG---FPVFATVIIANHVVVKDSKQV----VQSL 441
Query: 328 SDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGD 387
+D DI I KLS I + + S+APSIYGH++IK+A+ L L GG KN +RGD
Sbjct: 442 TDEDIATIQKLSKDPRIVERVVASMAPSIYGHDYIKRALALALFGGESKNPGEKHKVRGD 501
Query: 388 INILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAM 447
IN+L+ GDP TAKSQ L++ A A+ TTG+G+S VGLTA V + + E LEAGA+
Sbjct: 502 INLLICGDPGTAKSQFLKYTEKVAPRAVFTTGQGASAVGLTAYVRRNPVSREWTLEAGAL 561
Query: 448 VLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQ 507
VLAD+G+ IDEFDKM+D DR +IHE MEQQ+++I+KAGI T+L ARC+VIAAANP+ G+
Sbjct: 562 VLADQGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGR 621
Query: 508 YDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEPV 567
YD + +N+ L + +LSRFD+L VV D+ + ++D+ +++ V+ +H P E +P
Sbjct: 622 YDPSMTFSENVNLSEPILSRFDVLCVVKDEFDPMQDQQLAKFVVHSHMKHHPSE-EEQPE 680
Query: 568 REQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPF 627
E+ L E+PQ
Sbjct: 681 LEEPQLKTV----------------------------------------DEIPQ----DL 696
Query: 628 IRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQ-NTKKSPITARTLETLIRLSSAHAK 686
+R+YI YAKE I P+LT D I K Y+ LR + T PIT R +E++IR+S AHA+
Sbjct: 697 LRQYIVYAKENIRPKLTNIDEDKIAKMYAQLRQESFATGSLPITVRHIESVIRMSEAHAR 756
Query: 687 VRLSKKVELEDAKVATQLL 705
+ L + V D +A +++
Sbjct: 757 MHLRENVMEADVSMAIRMM 775
>At1g44900 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 928
Score = 313 bits (803), Expect = 6e-85
Identities = 206/569 (36%), Positives = 292/569 (51%), Gaps = 77/569 (13%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHY-----AQTTGHHHYRDYRDAXXXXXX 202
R + HLN +I + G+VTR S V P+L + V Y G Y +
Sbjct: 313 RNIRQIHLNTMIRIGGVVTRRSGVFPQL-QQVKYDCNKCGAVLGPFFQNSYSEVKVGSCS 371
Query: 203 SVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXX 262
E Q Y ++Q++T+QE P P G+LPR
Sbjct: 372 ----------ECQSKGPFTVNVEQTIYRNYQKLTIQESPGTVPAGRLPRHKEVILLNDLI 421
Query: 263 XKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGF---RTVVIGNTVYPLHARST 319
+PG+ I + G+Y +NN D +GF TVV N V +
Sbjct: 422 DCARPGEEIEVTGIY-----------TNNFDLSLNTKNGFPVFATVVEANYV----TKKQ 466
Query: 320 GVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLP 379
+ + L+ D I +LS I + + +S+APSIYGHE IK A+ L + GG EKN+
Sbjct: 467 DLFSAYKLTQEDKTQIEELSKDPRIVERIIKSIAPSIYGHEDIKTALALAMFGGQEKNIK 526
Query: 380 NGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGE 439
LRGDIN+L++GDP TAKSQ L++V T A+ TTG+G+S VGLTAAV D T E
Sbjct: 527 GKHRLRGDINVLLLGDPGTAKSQFLKYVEKTGQRAVYTTGKGASAVGLTAAVHKDPVTRE 586
Query: 440 RRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIA 499
LE GA+VLADRGI IDEFDKM+D DRV+IHE MEQQ+++I+KAGI T+L ARCSVIA
Sbjct: 587 WTLEGGALVLADRGICLIDEFDKMNDQDRVSIHEAMEQQSISISKAGIVTSLQARCSVIA 646
Query: 500 AANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPP 559
AANPV G+YD +K +N+ L D +LSRFD+L VV D ++ + D ++E V+ +H P
Sbjct: 647 AANPVGGRYDSSKSFAQNVELTDPILSRFDILCVVKDVVDPVTDEMLAEFVVNSHFKSQP 706
Query: 560 --GYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGS 617
G +E + I S+GS
Sbjct: 707 KGGKMEDSDPEDGIQ----------------------------------------GSSGS 726
Query: 618 ELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND-QNTKKSPITARTLET 676
P+++ ++KY+ Y+K + P+L + + Y+NLR + N + I R LE+
Sbjct: 727 TDPEVLPQNLLKKYLTYSKLYVFPKLGELDAKKLETVYANLRRESMNGQGVSIATRHLES 786
Query: 677 LIRLSSAHAKVRLSKKVELEDAKVATQLL 705
+IR+S AHA++ L + V ED +A ++L
Sbjct: 787 MIRMSEAHARMHLRQYVTEEDVNMAIRVL 815
>Hs20535929 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 904
Score = 313 bits (802), Expect = 8e-85
Identities = 210/561 (37%), Positives = 297/561 (52%), Gaps = 60/561 (10%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R+L HLN+LI G+VT + V P+L V Y + + + P
Sbjct: 295 RSLRQLHLNQLIRTSGVVTSCTGVLPQL-SMVKYNCNKCNFVLGPFCQSQNQEVKPGSCP 353
Query: 208 AIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKP 267
E Q Y ++QRI +QE P K G+LPRS KP
Sbjct: 354 -----ECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKP 408
Query: 268 GDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETL 327
GD I + G+Y + G L + NG F TV++ N V A+ AV L
Sbjct: 409 GDEIELTGIYHNNYDGSL-------NTANG-FPVFATVILANHV----AKKDNKVAVGEL 456
Query: 328 SDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSH-LRG 386
+D D++ I LS I + + S+APSIYGHE IK+ + L L GG KN P G H +RG
Sbjct: 457 TDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRG 515
Query: 387 DINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGA 446
DIN+L+ GDP TAKSQ L+++ ++ AI TTG+G+S VGLTA V + E LEAGA
Sbjct: 516 DINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGA 575
Query: 447 MVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFG 506
+VLADRG+ IDEFDKM+D DR +IHE MEQQ+++I+KAGI T+L ARC+VIAAANP+ G
Sbjct: 576 LVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Query: 507 QYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEP 566
+YD + +N+ L + ++SRFD+L VV D ++ ++D ++ V+ +H P E E
Sbjct: 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEG 695
Query: 567 VREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSE-LPQIVAI 625
L G+ ++ G E LPQ V
Sbjct: 696 ----------------------------------LANGSAAEPAMPNTYGVEPLPQEV-- 719
Query: 626 PFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND-QNTKKSPITARTLETLIRLSSAH 684
++KYI YAKER+ P+L Q D + K YS+LR + T PIT R +E++IR++ AH
Sbjct: 720 --LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAH 777
Query: 685 AKVRLSKKVELEDAKVATQLL 705
A++ L V +D +A +++
Sbjct: 778 ARIHLRDYVIEDDVNMAIRVM 798
>At2g07690 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 727
Score = 311 bits (797), Expect = 3e-84
Identities = 218/667 (32%), Positives = 324/667 (47%), Gaps = 88/667 (13%)
Query: 71 PLRITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDP-S 129
P R+ V L+DL FD + + P+ +LP E+A E L G +P +
Sbjct: 59 PKRLVVHLEDLLSFDSDLPSLIRSAPADYLPVFEKAAGEVLTGLKMREANEGGVMEEPLT 118
Query: 130 RQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHH 189
R ++ P S+ R L + +++KL+ + GI S V+ K +
Sbjct: 119 RDVQILLTSREDPVSM--RLLGAQYISKLVKISGISIAASRVKAKATYVFLVCKNCKKTR 176
Query: 190 YRDYRDAXXXXXX-----SVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKA 244
R ++P P EE + + Y+D Q + +QE PE
Sbjct: 177 EVPCRPGLGGAIVPRSCDNIPQPG---EEPCPLDPWMVVPDRSQYVDQQTLKLQENPEDV 233
Query: 245 PPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSG--F 302
P G+LPR+ PG R+ ++G+Y A S+N+ KG A+
Sbjct: 234 PTGELPRNMLLSVDRHLVQTIVPGTRLTVMGIYSIFQASS----SSNSHKGAVAIRQPYI 289
Query: 303 RTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHI 362
R V + +T A S G + + ++ K + +++ + +APSI+GHE +
Sbjct: 290 RVVGLEDTN---EASSRGPA---NFTPDEEEEFKKFADSQDVYKNICTKIAPSIFGHEDV 343
Query: 363 KKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGS 422
K+A +L GG K+LP+G LRGDIN+L++GDPSTAKSQ L+FV TA +A+ T+G+GS
Sbjct: 344 KRAAACLLFGGSRKSLPDGVKLRGDINVLLLGDPSTAKSQFLKFVEKTAPIAVYTSGKGS 403
Query: 423 SGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTI 482
S GLTA+V D T E LE GAMVLAD G+VCIDEFDKM DRVAIHE MEQQT++I
Sbjct: 404 SAAGLTASVIRDSSTREFYLEGGAMVLADGGVVCIDEFDKMRPEDRVAIHEAMEQQTISI 463
Query: 483 AKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIR 542
AKAGI T LN+R SV+AAANP G+YD K NI L ++LSRFDL+F+V D +
Sbjct: 464 AKAGITTVLNSRTSVLAAANPPSGRYDDLKTAQDNIDLQTTILSRFDLIFIVKDIRKYSQ 523
Query: 543 DRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLH 602
D+ I+ H++R +H
Sbjct: 524 DKEIASHIIR------------------------------------------------VH 535
Query: 603 AGA-KLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND 661
A A K + DS ++++YIQY + R P+L+++A + + + Y +R D
Sbjct: 536 ASANKFSDENTDSKEDN--------WLKRYIQYCRARCHPRLSKDAAENLQRKYVTIRMD 587
Query: 662 QNTKKS--------PITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALLGED 713
+ PIT R LE ++RLS + AK+RLS + +D A +L + +
Sbjct: 588 MKRRAHETGEAAPIPITVRQLEAIVRLSESLAKMRLSHEATPDDVDKAFKLFDTSTMDAA 647
Query: 714 GANFDEQ 720
+ ++Q
Sbjct: 648 RSGINQQ 654
>YBL023c [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 868
Score = 306 bits (785), Expect = 7e-83
Identities = 207/579 (35%), Positives = 313/579 (53%), Gaps = 53/579 (9%)
Query: 142 PNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXX 201
P S R L ++L+ L+ V G+VTR + V P+L G ++D+
Sbjct: 301 PTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIR 360
Query: 202 XSVPTPAIYPEEDQ-EGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXX 260
S T + G K V Y ++QR+T+QE P PPG+LPR
Sbjct: 361 ISFCTNCKSKGPFRVNGEKTV-------YRNYQRVTLQEAPGTVPPGRLPRHREVILLAD 413
Query: 261 XXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGF---RTVVIGNTVYPLHAR 317
+KPG+ + + G+YK NN D A +GF T++ N++
Sbjct: 414 LVDVSKPGEEVEVTGIYK-----------NNYDGNLNAKNGFPVFATIIEANSIKRREGN 462
Query: 318 ST--GVSAVETLS--DNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGG 373
+ G ++ S + + R K+S I D + S+APSIYGH IK A+ L GG
Sbjct: 463 TANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGG 522
Query: 374 VEKNLPNGSH-LRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVT 432
V KN+ NG H +RGDIN+L++GDP TAKSQ+L++V TA A+ TG+G+S VGLTA+V
Sbjct: 523 VPKNV-NGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVR 581
Query: 433 TDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLN 492
D T E LE GA+VLAD+G+ IDEFDKM+D DR +IHE MEQQ+++I+KAGI TTL
Sbjct: 582 KDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQ 641
Query: 493 ARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLR 552
ARCS+IAAANP G+Y+ +N++L + +LSRFD+L VV D +++ D ++ V+
Sbjct: 642 ARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVD 701
Query: 553 THRYLPPGY---LEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAK--L 607
+H P EGE ++ ++ G ++ N L+A +
Sbjct: 702 SHVRSHPENDEDREGEELKNNGESAIEQGE---------------DEINEQLNARQRRLQ 746
Query: 608 AKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQ-NTKK 666
+ + + S +PQ + KYI YA+ +I P+L Q +D + + Y++LR + +T
Sbjct: 747 RQRKKEEEISPIPQ----ELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGS 802
Query: 667 SPITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLL 705
PIT R LE+++R++ + AK+RLS+ V D A +++
Sbjct: 803 FPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVV 841
>SPBC4.04c [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 830
Score = 304 bits (779), Expect = 4e-82
Identities = 204/571 (35%), Positives = 296/571 (51%), Gaps = 66/571 (11%)
Query: 142 PNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXX 201
P + R L +HLN L+ V G+VTR + + P+L G ++D+
Sbjct: 294 PTCFTLRDLRQSHLNCLVRVSGVVTRRTGLFPQLKYIRFTCTKCGATLGPFFQDS----- 348
Query: 202 XSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXX 261
SV + V Y ++QRIT+QE P P G+LPR
Sbjct: 349 -SVEVKISFCHNCSSRGPFVINSERTVYNNYQRITLQESPGTVPSGRLPRHREVILLADL 407
Query: 262 XXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGF---RTVVIGNTVYPLHARS 318
KPG+ I++ G+Y+ NN D +GF T++ N + L
Sbjct: 408 VDVAKPGEEIDVTGIYR-----------NNFDASLNTKNGFPVFATIIEANHISQLDGSG 456
Query: 319 TGVS--AVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEK 376
++ L+D++ R I L+ +I + + S+APSIYGH IK AI L GGV K
Sbjct: 457 NTDDDFSLSRLTDDEEREIRALAKSPDIHNRIIASMAPSIYGHRSIKTAIAAALFGGVPK 516
Query: 377 NLPNGSH-LRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDK 435
N+ NG H +RGDIN+L++GDP TAKSQ L++V TA A+ TG+G+S VGLTA+V D
Sbjct: 517 NI-NGKHKIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFATGQGASAVGLTASVRKDP 575
Query: 436 ETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARC 495
T E LE GA+VLAD+G+ IDEFDKM+D DR +IHE MEQQ+++I+KAGI TTL ARC
Sbjct: 576 ITNEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARC 635
Query: 496 SVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHR 555
++IAAANP+ G+Y+ ++N+ L + +LSRFD+L VV D +N D ++ V+ +H
Sbjct: 636 TIIAAANPIGGRYNTTIPFNQNVELTEPILSRFDILQVVKDTVNPEIDEQLANFVVSSHI 695
Query: 556 YLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSN 615
P F+P + K+ G +
Sbjct: 696 RSHPA------------------------------------FDPNMDVLKKVPTETG-ID 718
Query: 616 GSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQ-NTKKSPITARTL 674
+PQ +RKYI +A+E++ P+L Q + I + YS++R + T PIT R L
Sbjct: 719 AKPIPQ----DLLRKYIHFAREKVFPRLQQMDEEKISRLYSDMRRESLATGSYPITVRHL 774
Query: 675 ETLIRLSSAHAKVRLSKKVELEDAKVATQLL 705
E+ IRLS A AK++LS+ V A Q++
Sbjct: 775 ESAIRLSEAFAKMQLSEFVRPSHIDKAIQVI 805
>YPR019w [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 933
Score = 303 bits (777), Expect = 6e-82
Identities = 199/587 (33%), Positives = 299/587 (50%), Gaps = 93/587 (15%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R LN ++KLI+++G+V R++ V P + + D+ A + P
Sbjct: 315 RELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVC------DHTMAVEIDRGVIQEP 368
Query: 208 AIYPEED-QEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTK 266
A D E N + + C + D Q I +QE P+ P GQ P S +
Sbjct: 369 ARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCR 428
Query: 267 PGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVV-------------------I 307
GDRI + G ++S+ N + S ++T V I
Sbjct: 429 AGDRIEVTGTFRSIPIRA-------NSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTI 481
Query: 308 GNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAIL 367
+ V V ++D D+ I +++ ++++ L++S+APSIY E +KK IL
Sbjct: 482 EQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGIL 541
Query: 368 LMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGL 427
L L GG K G RGDINIL+ GDPST+KSQ+L++V + T+G+GSS VGL
Sbjct: 542 LQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGL 601
Query: 428 TAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGI 487
TA +T D +T + LE+GA+VL+D G+ CIDEFDKMSD R +HEVMEQQT++IAKAGI
Sbjct: 602 TAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGI 661
Query: 488 HTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAIS 547
TTLNAR S++A+ANP+ +Y+ N +NI LP LLSRFDL+++V D +++ DR ++
Sbjct: 662 ITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELA 721
Query: 548 EHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKL 607
+H+ YLE +P E I+
Sbjct: 722 KHLTNL-------YLEDKP--EHISQD--------------------------------- 739
Query: 608 AKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLR---NDQNT 664
++ + F+ YI YAKE I P +T+ A ++++Y +R +D +
Sbjct: 740 -------------DVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRS 786
Query: 665 KKSPITA--RTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFAL 709
+ ITA R LE++IRL+ AHAK++L VELED + A +L+R A+
Sbjct: 787 DEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAI 833
>CE03558 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 759
Score = 303 bits (776), Expect = 8e-82
Identities = 211/707 (29%), Positives = 346/707 (48%), Gaps = 77/707 (10%)
Query: 25 DTHSHYTREIRSILEFNSNVVKEKKTDDDYLNTADKDTMDHDTNQLPLRITVSLDDLREF 84
DT E R ++ N +++ T + D+ ++ +++ R+ ++L+ L+ F
Sbjct: 23 DTGRELIAEYRQLITQFRNFIRDFSTGGFGMIYRDQLKRNYFSHEY--RLEINLNHLKNF 80
Query: 85 DKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQWRLSFKGSFGPNS 144
D+ L + P LP A+ E A + D R + +++ P S
Sbjct: 81 DEDIEMKLRKFPGKVLP----ALEEAAKIVADEITTPRPKGEEKLHDIQVTLTLDEYPTS 136
Query: 145 LSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSV 204
L R + S +++++ + GI+ + VR K + + H D ++
Sbjct: 137 L--RQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQC-KHTIPDVSIKPGLEGFAL 193
Query: 205 PTPAIYPEEDQEGNKLVTEYGF----CHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXX 260
P P++ Q + Y C +D+Q + +QE PE P G++PR
Sbjct: 194 PRTCAAPQQGQMQRCPIDPYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERY 253
Query: 261 XXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTG 320
K PG+R+ IVGVY GG + L G RT + + G
Sbjct: 254 LTDKVVPGNRVTIVGVYSIKKLIQKKGGDKS-------LQGIRTPYLRVLGIHMETSGPG 306
Query: 321 VSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPN 380
+ T + + R L+ + ++ +++S+APSIYG IKK+I +L GG K LP+
Sbjct: 307 RTNFTTFTPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPD 366
Query: 381 GSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGER 440
G RGDIN+L++GDP TAKSQ+L+FV + + + T+G+GSS GLTA+V D ++
Sbjct: 367 GITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSF 426
Query: 441 RLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAA 500
+E GAMVLAD G+VCIDEFDKM + DRVAIHE MEQQT++IAKAGI TTLN+RCSV+AA
Sbjct: 427 IMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAA 486
Query: 501 ANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPG 560
AN V+G++D ++ NI ++LSRFD++++V D + ++D +++HV+ H
Sbjct: 487 ANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVH------ 539
Query: 561 YLEGEPVREQINLSLA-----VGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSN 615
+N S A G +F D++
Sbjct: 540 ----------VNASAAKERDIAGVPKTATTDSDGVMTMF------------------DTD 571
Query: 616 GSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND-------QNTKKS- 667
G + I F++K++ YA+ P+LT +A + ++ Y +RN ++ KK+
Sbjct: 572 G-----FLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNPVVNADAFKSGKKAH 626
Query: 668 ----PITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALL 710
PIT R LE ++R++ + AK+ L + + + A +L R + +
Sbjct: 627 NSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTI 673
>SPAC3F10.01 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 649
Score = 302 bits (774), Expect = 1e-81
Identities = 208/618 (33%), Positives = 308/618 (49%), Gaps = 96/618 (15%)
Query: 92 LLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQWRLSFKGSFGPNSLSPRTLN 151
LL P+ LP E AV+ A L +R +N + + N L R L
Sbjct: 11 LLSQPTDILPLFESAVTTVAKRLL-----YRSQENASTNIPTCQVTLRYDANILPIRNLT 65
Query: 152 STHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAX----XXXXXSVPTP 207
++H++KL+ V GI+ S + + T H R+ R V P
Sbjct: 66 ASHISKLVRVPGIIIGASTLSCRA--------TALHLVCRNCRATRILQISGGFSGVQLP 117
Query: 208 AIYPEEDQEGNK-------LVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXX 260
+ +G K + ++ ++D Q + +QE P+ P G+LPR
Sbjct: 118 RVCEAPVLDGEKKDCPMDPFIIDHSKSTFIDQQVLKLQEAPDMVPVGELPRHILLNADRY 177
Query: 261 XXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTG 320
+ PG R I G++ N + K +GA++ R I + + G
Sbjct: 178 LTNQITPGTRCVITGIFSIF--------QNKSVKASGAVA-IRNPYIRVVGIQMDSND-G 227
Query: 321 VSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPN 380
+ S+ + ++S N++D +S S++P+IYG+ IKKAI +L G +K LP+
Sbjct: 228 SKSTPLFSEEEEEEFLEISRTPNLYDIISNSISPAIYGNVDIKKAIACLLFSGSKKILPD 287
Query: 381 GSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGER 440
G LRGDIN+L++GDP TAKSQ L+FV A +A+ T+G+GSS GLTA++ D T E
Sbjct: 288 GMRLRGDINVLLLGDPGTAKSQFLKFVERLAPIAVYTSGKGSSAAGLTASIQRDSVTREF 347
Query: 441 RLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAA 500
LE GAMVLAD GIVCIDEFDKM D DRVAIHE MEQQT++IAKAGI T LN+R SV+AA
Sbjct: 348 YLEGGAMVLADGGIVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNSRTSVLAA 407
Query: 501 ANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPG 560
ANP+FG+YD K P +NI ++LSRFD++F+V D+ ++ +DR I+ HV+ H L
Sbjct: 408 ANPIFGRYDDMKTPGENIDFQSTILSRFDMIFIVKDEHDETKDRNIARHVINLHTNL--- 464
Query: 561 YLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELP 620
++ + +LA+G + F+KF
Sbjct: 465 --------QESSETLAIG------------EIPFDKF----------------------- 481
Query: 621 QIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLR-------NDQNTKKS-PITAR 672
R+YI Y + + P L EA + + + +R D N++ + PIT R
Sbjct: 482 --------RRYINYCRHKCAPNLDAEAAEKLSSQFVAIRKRVHQSEQDSNSRSTIPITVR 533
Query: 673 TLETLIRLSSAHAKVRLS 690
LE +IR++ + AK+ LS
Sbjct: 534 QLEAIIRITESLAKMSLS 551
>SPBC25D12.03c [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 760
Score = 302 bits (773), Expect = 2e-81
Identities = 194/571 (33%), Positives = 290/571 (49%), Gaps = 44/571 (7%)
Query: 25 DTHSHYTREIRSILEFNSNVVKEKKTDDDYLNTADKDTMDHDTNQLPLRITVSLDDLREF 84
D SH+ +E + N ++ D+ +L + D + +N+ I V L+DL EF
Sbjct: 22 DFLSHFKQEQVQDGQQNQDISMSDAGDEPFLKSKYMDILQKISNRESNVINVDLNDLYEF 81
Query: 85 D--------------KTFWTGLLQVPSFFLPPAERAVSETAMALD-----------DSPL 119
D K F Q +PP ++ LD +
Sbjct: 82 DPSDTQLLHNIESNAKRFVELFSQCADALMPPPTVEINYRNEVLDVIMQQRVQRNENIDP 141
Query: 120 GFRGFQNDPSRQWRLSFKG-SFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRS 178
+GF + +R + L F+ + S R L +L L++V GIVTRTS V+P L +
Sbjct: 142 EHKGFPPELTRGYDLYFRPVTRNKKPFSVRDLRGENLGSLLTVRGIVTRTSDVKPSLTVN 201
Query: 179 VHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQ 238
+ G+ +++ R P+ + D +G ++ ++ Q + +Q
Sbjct: 202 AYTCDRCGYEVFQEIRQKTFLPMSECPSDEC-KKNDAKGQLFMSTRA-SKFLPFQEVKIQ 259
Query: 239 EMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGA 298
E+ + P G +PRS PGD ++I G++ G
Sbjct: 260 ELTNQVPIGHIPRSLTVHLYGAITRSVNPGDIVDISGIFLPTPYTGFRA----------- 308
Query: 299 LSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRN--INKLSMHDNIFDTLSQSLAPSI 356
R ++ +T H S + + I +L+ N+++ L++S+AP I
Sbjct: 309 ---MRAGLLTDTYLECHYVSQIIKNYTNIEKTPQSEAAIAELNQGGNVYEKLAKSIAPEI 365
Query: 357 YGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIA 416
YGHE +KKA+LL+L+GGV K L +G +RGDINI + GDP AKSQ+L+++ A +
Sbjct: 366 YGHEDVKKALLLLLVGGVTKELGDGMRIRGDINICLTGDPGVAKSQLLKYISKVAPRGVY 425
Query: 417 TTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVME 476
TTGRGSSGVGLTAAV D T E LE GA+VLAD GI CIDEFDKM + DR AIHEVME
Sbjct: 426 TTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGICCIDEFDKMDESDRTAIHEVME 485
Query: 477 QQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTD 536
QQT++I+KAGI TTLNAR S++AAANP++G+Y+ P NI LP +LLSRFD+LF++ D
Sbjct: 486 QQTISISKAGITTTLNARTSILAAANPLYGRYNPKVAPIHNINLPAALLSRFDILFLILD 545
Query: 537 DINDIRDRAISEHVLRTHRYLPPGYLEGEPV 567
+ D +++HV H + ++ EP+
Sbjct: 546 TPSRETDEHLAQHVTYVHMHNEQPKMDFEPL 576
>At4g02060 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 716
Score = 301 bits (772), Expect = 2e-81
Identities = 210/632 (33%), Positives = 319/632 (50%), Gaps = 93/632 (14%)
Query: 92 LLQVPSFFLPPAERAVSETAMALD--DSPLGFRGFQNDPS---RQWRLSFKGSFGPNSLS 146
LL P+ P + + T A D D+P Q PS R + + FK +
Sbjct: 83 LLPEPTEAFPDDDHDILMTQRADDGTDNPDVSDPHQQIPSEIKRYYEVYFKAPSKGRPST 142
Query: 147 PRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPT 206
R + ++H+ +L+ + GIVTR S V+P + +V+ + GH Y++ P+
Sbjct: 143 IREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPS 202
Query: 207 PAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTK 266
+ GN ++ + ++ Q +QE+ E P G +PRS K
Sbjct: 203 SRCRLNS-KAGNPIL-QLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVS 260
Query: 267 PGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVET 326
PGD + G++ + +GF+ + G V + +T V+ +
Sbjct: 261 PGDVVEFSGIFLPI-----------------PYTGFKALRAG-LVADTYLEATSVTHFKK 302
Query: 327 ------LSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPN 380
++ I +L+ +I++ LS+SLAP IYGHE IKKA+LL+L+G + L +
Sbjct: 303 KYEEYEFQKDEEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKD 362
Query: 381 GSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGER 440
G +RGD++I ++GDP AKSQ+L+ ++N A + TTG+GSSGVGLTAAV D+ T E
Sbjct: 363 GMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMRDQVTNEM 422
Query: 441 RLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAA 500
LE GA+VLAD GI IDEFDKM + DR AIHEVMEQQTV+IAKAGI T+LNAR +V+AA
Sbjct: 423 VLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAA 482
Query: 501 ANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPG 560
ANP +G+YD+ + P +NI LP +LLSRFDLL+++ D + D +++HVL H
Sbjct: 483 ANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVH------ 536
Query: 561 YLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNP-LLHAGAKLAKNRGDSNGSEL 619
Q S A+G FE P +L A A+ +EL
Sbjct: 537 ---------QTEESPALG---------------FEPLEPNILRAYISAARRLSPYVPAEL 572
Query: 620 PQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQ---NTKKSPITARTLET 676
+ +A +YS++R ++ NT S T RTL +
Sbjct: 573 EEYIA----------------------------TAYSSIRQEEAKSNTPHSYTTVRTLLS 604
Query: 677 LIRLSSAHAKVRLSKKVELEDAKVATQLLRFA 708
++R+S+A A++R S+ V D A +L++ +
Sbjct: 605 ILRISAALARLRFSESVAQSDVDEALRLMQMS 636
>CE19038 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 881
Score = 300 bits (769), Expect = 5e-81
Identities = 201/561 (35%), Positives = 288/561 (50%), Gaps = 62/561 (11%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R L HLN LI G+VT S + P+L + G+ P
Sbjct: 271 RMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGY-----LLGPFVQQNDEEVRP 325
Query: 208 AIYPEEDQEGN-KLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTK 266
I P +G +L E H ++QRIT+QE P K G+LPRS K
Sbjct: 326 TICPSCQGKGPFELNVENTVYH--NYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCK 383
Query: 267 PGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVET 326
PGD I + GVY +NN D GF V ++ H + A +
Sbjct: 384 PGDEIEVTGVY-----------TNNFDGSLNYKQGF--PVFNTLIHANHITNKDKMASDQ 430
Query: 327 LSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSH-LR 385
L+D DI+ I +LS NI + S+APSIYGH+ +K+AI L L G KN P H LR
Sbjct: 431 LTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKN-PGAKHRLR 489
Query: 386 GDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAG 445
GDIN+L+ GDP TAKSQ LR+ + A ++ TTG+G+S VGLTA V T E LEAG
Sbjct: 490 GDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAG 549
Query: 446 AMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVF 505
AMVLAD+G+ IDEFDKMSD DR +IHE MEQQ+++I+KAGI T+L+ARC+VIAA+NP+
Sbjct: 550 AMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIG 609
Query: 506 GQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGE 565
G+Y+ + +N+ L + +LSRFD+L V+ D ++ + D +++ V+ HR P
Sbjct: 610 GRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHP------ 663
Query: 566 PVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAI 625
++ G +L +++ D +++
Sbjct: 664 ------------------------------DAKKIVKEGDELEEDQMDERTG--VRLIPQ 691
Query: 626 PFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND-QNTKKSPITARTLETLIRLSSAH 684
+RKYI YA+E+ P L ++ + ++ +R + T IT R +E++IRLS AH
Sbjct: 692 DLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGSVAITVRHVESMIRLSEAH 751
Query: 685 AKVRLSKKVELEDAKVATQLL 705
AK+ L V ED A +++
Sbjct: 752 AKLHLRSYVNDEDCAAAIRVM 772
>Hs14738665 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 863
Score = 298 bits (763), Expect = 3e-80
Identities = 211/649 (32%), Positives = 323/649 (49%), Gaps = 100/649 (15%)
Query: 74 ITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQWR 133
+ V+ + ++ FDK + L+ P +P + AV+E + D P D + +
Sbjct: 208 LNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNE--IFFDRYP--------DSILEHQ 257
Query: 134 LSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDY 193
+ + + + R LN +++LI++ G+V RTS + P++ + Q H R
Sbjct: 258 IQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTT-RVE 316
Query: 194 RDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSX 253
D SV + + + + D Q I +QE PE P GQ P +
Sbjct: 317 MDRGRIAEPSVCGRC------HTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTV 370
Query: 254 XXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYP 313
K +PGDR+N+ G+Y+++ N + + S ++T +
Sbjct: 371 ILFAHNDLVDKVQPGDRVNVTGIYRAVPI-------RVNPRVSNVKSVYKT-----HIDV 418
Query: 314 LHARSTGVSAVETL---------SDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKK 364
+H R T + L S+ + + +LS +I++ L+ +LAPSIY HE IKK
Sbjct: 419 IHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKK 478
Query: 365 AILLMLMGGVEKNLPNGSH--LRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGS 422
ILL L GG K+ + R +INIL+ GDP T+KSQ+L++V N T+G+GS
Sbjct: 479 GILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGS 538
Query: 423 SGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTI 482
S VGLTA V D ET + L+ GA+VL+D GI CIDEFDKM++ R +HEVMEQQT++I
Sbjct: 539 SAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSI 598
Query: 483 AKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIR 542
AKAGI LNAR SV+AAANP+ Q++ K +NI LP +LLSRFDL+F++ D ++
Sbjct: 599 AKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAY 658
Query: 543 DRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLH 602
DR ++ H++ Y + E E+ L +AV
Sbjct: 659 DRRLAHHLVAL-------YYQSEEQAEEELLDMAV------------------------- 686
Query: 603 AGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQ 662
++ YI YA I+P+L++EA +I++Y ++R
Sbjct: 687 -------------------------LKDYIAYAHSTIMPRLSEEASQALIEAYVDMRK-I 720
Query: 663 NTKKSPITA--RTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFAL 709
+ + ++A R LE+LIRL+ AHAKVRLS KVE D + A +L R AL
Sbjct: 721 GSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREAL 769
>Hs6981192 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 733
Score = 295 bits (755), Expect = 2e-79
Identities = 231/749 (30%), Positives = 346/749 (45%), Gaps = 123/749 (16%)
Query: 3 DAMNQTSDAVFTDRMRRFQEFLDTHSHYTREIRSILEFNSNVVKEKKTDDDYLNTADKDT 62
DA A + RRF+EFL R+ R TD +D
Sbjct: 18 DAQADEGQARKSQLQRRFKEFL-------RQYRV------------GTDRTGFTFKYRDE 58
Query: 63 MDHDTNQLPLRITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFR 122
+ N I V ++DL FD+ L + P+ L E A E A D R
Sbjct: 59 LKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVA----DEVTRPR 114
Query: 123 GFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRS---- 178
+ + ++ K P+S+ R+L S ++ L+ + GI+ S VR K R
Sbjct: 115 PSGEEVLQDIQVMLKSDASPSSI--RSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQC 172
Query: 179 -------VHYAQTTGHHHYRDYRDAXXXXXXSVPTPA----IYPEEDQEGNKLVTEYGFC 227
+ A G Y R P I P++ C
Sbjct: 173 RSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDK-------------C 219
Query: 228 HYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTG 287
+D Q + +QE+P+ P G++PR K PG+R+ I+G+Y S+ GLT
Sbjct: 220 KCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIY-SIKKFGLTT 278
Query: 288 GSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDT 347
+ G G S + V+ + +G S +S + +L+ N+++
Sbjct: 279 SRGRDRVGVGIRSSYIRVL----GIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEV 334
Query: 348 LSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFV 407
+S+S+APSI+G +KKAI +L GG K LP+G RGDIN+LM+GDP TAKSQ+L+FV
Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394
Query: 408 LNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVD 467
+ + + T+G+GSS GLTA+V D + +E GAMVLAD G+VCIDEFDKM + D
Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454
Query: 468 RVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSR 527
RVAIHE MEQQT++IAKAGI TTLN+RCSV+AAAN VFG++D K NI ++LSR
Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513
Query: 528 FDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXX 587
FD++F+V D+ N++RD +++HV+ H + + V +I+L
Sbjct: 514 FDMIFIVKDEHNEVRDVMLAKHVITLH---VSALTQTQAVEGEIDL-------------- 556
Query: 588 XXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEA 647
AKL K +I Y + + P+L+ EA
Sbjct: 557 -----------------AKLKK---------------------FIAYCRVKCGPRLSAEA 578
Query: 648 VDVIIKSYSNLRNDQNTKKS-------PITARTLETLIRLSSAHAKVRLSKKVELEDAKV 700
+ + Y +R + + PIT R LE ++R++ A +K++L D +
Sbjct: 579 AEKLKNRYIIMRTGPVSTRGTVTASSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEE 638
Query: 701 ATQLLRFALLGEDGANFDEQEFAEGRTTE 729
A +L + + L D A EG T++
Sbjct: 639 ALRLFQVSTL--DAALSGTLSGVEGFTSQ 665
>Hs11418031 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 734
Score = 294 bits (753), Expect = 4e-79
Identities = 233/750 (31%), Positives = 348/750 (46%), Gaps = 124/750 (16%)
Query: 3 DAMNQTSDAVFTDRMRRFQEFLDTHSHYTREIRSILEFNSNVVKEKKTDDDYLNTADKDT 62
DA A + RRF+EFL R+ R TD +D
Sbjct: 18 DAQADEGQARKSQLQRRFKEFL-------RQYRV------------GTDRTGFTFKYRDE 58
Query: 63 MDHDTNQLPLRITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFR 122
+ N I V ++DL FD+ L + P+ L E A E A D R
Sbjct: 59 LKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVA----DEVTRPR 114
Query: 123 GFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRS---- 178
+ + ++ K P+S+ R+L S ++ L+ + GI+ S VR K R
Sbjct: 115 PSGEEVLQDIQVMLKSDASPSSI--RSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQC 172
Query: 179 -------VHYAQTTGHHHYRDYRDAXXXXXXSVPTPA----IYPEEDQEGNKLVTEYGFC 227
+ A G Y R P I P++ C
Sbjct: 173 RSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDK-------------C 219
Query: 228 HYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTG 287
+D Q + +QE+P+ P G++PR K PG+R+ I+G+Y S+ GLT
Sbjct: 220 KCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIY-SIKKFGLTT 278
Query: 288 GSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDT 347
+ G G S + V+ + +G S +S + +L+ N+++
Sbjct: 279 SRGRDRVGVGIRSSYIRVL----GIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEV 334
Query: 348 LSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFV 407
+S+S+APSI+G +KKAI +L GG K LP+G RGDIN+LM+GDP TAKSQ+L+FV
Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394
Query: 408 LNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVD 467
+ + + T+G+GSS GLTA+V D + +E GAMVLAD G+VCIDEFDKM + D
Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454
Query: 468 RVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSR 527
RVAIHE MEQQT++IAKAGI TTLN+RCSV+AAAN VFG++D K NI ++LSR
Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513
Query: 528 FDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXX 587
FD++F+V D+ N+ RD +++HV+ H + + V +I+L
Sbjct: 514 FDMIFIVKDEHNEERDVMLAKHVITLH---VSALTQTQAVEGEIDL-------------- 556
Query: 588 XXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEA 647
AKL K +I Y + + P+L+ EA
Sbjct: 557 -----------------AKLKK---------------------FIAYCRVKCGPRLSAEA 578
Query: 648 VDVIIKSYSNLRN-------DQNTKKS-PITARTLETLIRLSSAHAKVRLSKKVELEDAK 699
+ + Y +R+ D + + S PIT R LE ++R++ A +K++L D +
Sbjct: 579 AEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVE 638
Query: 700 VATQLLRFALLGEDGANFDEQEFAEGRTTE 729
A +L + + L D A EG T++
Sbjct: 639 EALRLFQVSTL--DAALSGTLSGVEGFTSQ 666
>Hs21359886 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 719
Score = 294 bits (752), Expect = 5e-79
Identities = 167/439 (38%), Positives = 258/439 (58%), Gaps = 23/439 (5%)
Query: 130 RQWRLSFKGSFGPNSLSPRTLNSTH---LNKLISVEGIVTRTSLVRPKLLRSVHYAQTTG 186
R++ L F+G P+S PR + + KL++V GIVTR S V+PK++ + + G
Sbjct: 132 RRFELYFQG---PSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCG 188
Query: 187 HHHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPP 246
Y+ + P+ + ++ G +L + ++ Q + +QE ++ P
Sbjct: 189 AETYQPIQSPTFMPLIMCPSQEC--QTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPV 246
Query: 247 GQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVV 306
G +PRS +PGD +++ G++ + G G LS T +
Sbjct: 247 GNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGF------RQVVQGLLS--ETYL 298
Query: 307 IGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAI 366
+ + ++ S L+ ++R I + ++ ++ L+ S+AP IYGHE +KKA+
Sbjct: 299 EAHRIVKMNKSEDDESGAGELTREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKAL 354
Query: 367 LLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVG 426
LL+L+GGV+++ P G +RG+INI ++GDP AKSQ+L ++ A + TTGRGSSGVG
Sbjct: 355 LLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 413
Query: 427 LTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAG 486
LTAAV D +GE LE GA+VLAD+G+ CIDEFDKM++ DR AIHEVMEQQT++IAKAG
Sbjct: 414 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAG 473
Query: 487 IHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAI 546
I TTLNARCS++AAANP +G+Y+ + +NI LP +LLSRFDLL+++ D + D +
Sbjct: 474 ILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRL 533
Query: 547 SEHVLRTHRY--LPPGYLE 563
++H+ H++ PP E
Sbjct: 534 AQHITYVHQHSRQPPSQFE 552
>CE21767 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 823
Score = 292 bits (748), Expect = 1e-78
Identities = 223/709 (31%), Positives = 344/709 (48%), Gaps = 109/709 (15%)
Query: 15 DRMRRFQEFLDTHS-HYTREIRSILEFNSNVVKEKKTDDDYLNTADKDTMDHDTNQLPLR 73
D R F++FL T E +++ + + E + Y + D +
Sbjct: 116 DVQRSFRDFLTTFKISQLAEDENMMTGHDEALHEIDVNHPYYMERLLECNDAEVTH---- 171
Query: 74 ITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLG----FRGFQNDPS 129
I ++L L F + + ++ P+ +P + V+E + L R F +
Sbjct: 172 INLNLKHLNAFSEALYRKVIAYPADVIPYLDIVVNEVFAERFNRTLAQSIELRPFNAQKT 231
Query: 130 RQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHH 189
R R LN +++LI++ G+VTRTS + P++ RS ++
Sbjct: 232 RNMR---------------GLNPNDVDQLITISGMVTRTSSLIPEM-RSGYFQCAVCAFG 275
Query: 190 YRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQL 249
D V T + +LV ++D Q + +QE P+ P G+
Sbjct: 276 IESEVDKGRIEEPVVCTNC----SNTHCFQLVHNRSV--FLDKQVVKLQESPDDMPSGET 329
Query: 250 PRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGN 309
P + +PGDRI + G++++ G N K S +RT
Sbjct: 330 PHTVSVYAHGSLVESVQPGDRITVTGIFRATGM-------KVNPKQRALASVYRT----- 377
Query: 310 TVYPLHARSTGVSAV-----ETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKK 364
++ LH R S + ET+++ I+ I +LS +I D L+QS+APSIY H+ +K+
Sbjct: 378 SIDALHFRKMDTSRLHQDNGETITEERIQQIIELSKRPDIMDALAQSIAPSIYEHDDVKR 437
Query: 365 AILLMLMGGVEKN--LPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGS 422
+L +L GG K+ N + LR +INIL+ GDP T+KSQML++V + T+G+GS
Sbjct: 438 GLLCLLFGGTRKDDETTNKTKLRSEINILLCGDPGTSKSQMLQYVYRLLPRSQYTSGKGS 497
Query: 423 SGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTI 482
S VGLTA+V+ D +T + L+ GA+VLAD G+ CIDEFDKM++ R +HEVMEQQT++I
Sbjct: 498 SAVGLTASVSRDADTKQLVLQTGALVLADNGVCCIDEFDKMNESARSVLHEVMEQQTLSI 557
Query: 483 AKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIR 542
AKAGI LNAR SV+AAANPV +++ NK +NI LP +LLSRFDL+F++ D ++++
Sbjct: 558 AKAGIICQLNARASVLAAANPVDSKWNRNKTIVENITLPHTLLSRFDLIFLIVDAQDEMQ 617
Query: 543 DRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLH 602
DR + H++ Y E + +E+ H
Sbjct: 618 DRRLGNHLVSL-------YFENDGNQEKTE-----------------------------H 641
Query: 603 AGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQ 662
L ++ YI YAK I P+L++EA II+ Y +R
Sbjct: 642 VDMNLLRD--------------------YIAYAKANIHPKLSEEASQFIIEKYLFMRK-A 680
Query: 663 NTKKSPITA--RTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFAL 709
+ ITA R LE+LIRLS AHAK+RLS++V ++D + A L R AL
Sbjct: 681 GAQHGQITAYPRQLESLIRLSEAHAKIRLSQEVSVDDVEKAFTLWREAL 729
>7299365 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 733
Score = 292 bits (748), Expect = 1e-78
Identities = 221/682 (32%), Positives = 324/682 (47%), Gaps = 107/682 (15%)
Query: 74 ITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLGFRGFQNDPSRQWR 133
+ + ++DL FD+T L + P+ L E A E A D R + +
Sbjct: 65 LEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVA----DEITAPRPEHEEHMHDIQ 120
Query: 134 LSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSV-----------HYA 182
+ + P ++ R L S ++KL+ + GI+ S + K R +
Sbjct: 121 ILLSSNANPTNI--RQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLK 178
Query: 183 QTTGHHHYRDYRDAXXXXXXSVPTPA----IYPEEDQEGNKLVTEYGFCHYMDHQRITVQ 238
G Y R P I P++ C +D Q + +Q
Sbjct: 179 VNPGLEGYALPRKCNTEQAGRPKCPLDPFFIMPDK-------------CKCVDFQTLKLQ 225
Query: 239 EMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGA 298
E+P+ P G++PR + PG+R+ I G+Y G + D A
Sbjct: 226 ELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGK----PSRRDGREKA 281
Query: 299 LSGFRTV---VIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPS 355
+ G R V+G TV A + +S ++ ++ + +++ +I++ LSQSLAPS
Sbjct: 282 VVGVRAPYMRVVGITVDSEGAGA--ISRYSNITSDEEEHFRRMAASGDIYERLSQSLAPS 339
Query: 356 IYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAI 415
I+G IKKAI ML GG K LP+G RGDIN+L++GDP TAKSQ+L+FV A +A+
Sbjct: 340 IFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAV 399
Query: 416 ATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVM 475
T+G+GSS GLTA+V D +T +E GAMVLAD G+VCIDEFDKM + DRVAIHE M
Sbjct: 400 YTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAM 459
Query: 476 EQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVT 535
EQQT++IAKAGI TTLN+RCSV+AAAN +FG++D K +NI ++LSRFD++F+V
Sbjct: 460 EQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVK 518
Query: 536 DDINDIRDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFE 595
D ++ RD +++H++ H EP +I+LS
Sbjct: 519 DIHDESRDITLAKHIINVHLSSNKS-APSEPAEGEISLST-------------------- 557
Query: 596 KFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSY 655
+KYI Y + P+L++ A + + Y
Sbjct: 558 --------------------------------FKKYIHYCRTHCGPRLSEAAGEKLKSRY 585
Query: 656 SNLRN--DQNTKKS------PITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRF 707
+R+ Q K S PIT R LE +IR+S + AK+RL E A +L +
Sbjct: 586 VLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQV 645
Query: 708 ALLGEDGANFDEQEFAEGRTTE 729
+ L D A AEG TTE
Sbjct: 646 STL--DAAMTGSLAGAEGFTTE 665
>7295030 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 720
Score = 291 bits (746), Expect = 2e-78
Identities = 213/673 (31%), Positives = 329/673 (48%), Gaps = 118/673 (17%)
Query: 74 ITVSLDDLREFDKTFWTGLL-----------QVPSFFLPPAERAVSETAMALD------- 115
IT+ LDDL EF+++ ++ V + LP ++ ALD
Sbjct: 48 ITIDLDDLAEFNESLAEAVVDNCRRYTSIFSDVIAELLPSYKQQEVHAKDALDVYIEHRL 107
Query: 116 ------DSPLGFR----GFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIV 165
+P+ R F ++ +++ + FK + S R + + H+ KL++V GIV
Sbjct: 108 MMESRTRNPMEQRDERNSFPSELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIV 167
Query: 166 TRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYG 225
TR + V+P ++ + + G Y+ P+ ++ G +L +
Sbjct: 168 TRCTEVKPMMVVATYTCDRCGSETYQPVNSLSFTPVHDCPSDDC--RVNKAGGRLYLQTR 225
Query: 226 FCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGL 285
++ Q + +QE ++ P G +PRS +PGD I + GV+ L
Sbjct: 226 GSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVTRMAQPGDHIVVSGVFLPL----- 280
Query: 286 TGGSNNNDKGNGALSGFRTVVIG---NTVYPLHARSTGVSAVETLSDNDI----RNINKL 338
+GF ++ G T H R ++ + +SD D + +L
Sbjct: 281 ------------MRTGFAQMIQGLLSETFLQAH-RIICINKNDEISDKDAELTPEELEEL 327
Query: 339 SMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPST 398
+ D+ ++ L+ SLAP IYGH +KKA+LL+L+GGV+K P+G +RG+INI ++GDP
Sbjct: 328 A-QDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKR-PDGMKIRGNINICLMGDPGV 385
Query: 399 AKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCID 458
AKSQ+L ++ A + TTGRGSSGVGLTAAV D TGE LE GA+VLAD+G+ CID
Sbjct: 386 AKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCID 445
Query: 459 EFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNI 518
EFDKM+D DR AIHEVMEQQT++IAKAGI TTLNAR S++AAANP FG+Y+ + +NI
Sbjct: 446 EFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNI 505
Query: 519 ALPDSLLSRFDLLFVVTDDINDIRDRAISEHV--LRTHRYLPPGYLEGEPVREQINLSLA 576
LP +LLSRFDLL+++ D + D +++H+ + +H PP ++ +
Sbjct: 506 QLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMN-------- 557
Query: 577 VGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAK 636
L+ L K + + EL + + Y++ +
Sbjct: 558 -----------------------LMRRYINLCKRKNPTIPDELTDYI----VGAYVELRR 590
Query: 637 ERIIPQLTQEAVDVIIKSYSNLRNDQNTKKSPIT-ARTLETLIRLSSAHAKVRLSKKVEL 695
E +N K T AR L ++RLS+A A++RLS VE
Sbjct: 591 EA-----------------------RNQKDMTFTSARNLLGILRLSTALARLRLSDSVEK 627
Query: 696 EDAKVATQLLRFA 708
+D A +LL +
Sbjct: 628 DDVAEALRLLEMS 640
>Hs4758706 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 892
Score = 281 bits (720), Expect = 3e-75
Identities = 196/533 (36%), Positives = 274/533 (50%), Gaps = 60/533 (11%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R+L HLN+LI G+VT + V P+L V Y + + + P
Sbjct: 284 RSLRQLHLNQLIRTSGVVTSCTGVLPQL-SMVKYNCNKCNFVLGPFCQSQNQEVKPGSCP 342
Query: 208 AIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKP 267
E Q Y ++QRI +QE P K +LPRS
Sbjct: 343 -----ECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAARRLPRSKDAILLADLVDSCNA 397
Query: 268 GDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETL 327
GD I + G+Y + G L + NG F TV++ N V A+ AV L
Sbjct: 398 GDEIELTGIYHNNYDGSL-------NTANG-FPVFATVILANHV----AKKDNKVAVGEL 445
Query: 328 SDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSH-LRG 386
+D D++ I LS I + + S+APSIYGHE IK+ L L GG KN P G H +RG
Sbjct: 446 TDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGPALALFGGEPKN-PGGKHKVRG 504
Query: 387 DINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGA 446
DIN+L+ GDP TAKSQ L+++ ++ AI TTG+G+S V +TA V + E LEAGA
Sbjct: 505 DINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVAVTAYVQRHPVSREWTLEAGA 564
Query: 447 MVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFG 506
+VLADRG+ IDEFDKM+D DR +IHE MEQQ+++I+KAGI T+L ARC+VIAAANP+ G
Sbjct: 565 LVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 624
Query: 507 QYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEP 566
+YD + +N+ L + ++SRFD+L VV D ++ ++D ++ V+ +H P E E
Sbjct: 625 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEG 684
Query: 567 VREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSE-LPQIVAI 625
L G+ ++ G E LPQ V
Sbjct: 685 ----------------------------------LANGSAAEPAMPNTYGVEPLPQEV-- 708
Query: 626 PFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND-QNTKKSPITARTLETL 677
++KYI YAKER+ P+L Q D + K YS+LR + T PIT R +E++
Sbjct: 709 --LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESM 759
>ECU02g1150 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 708
Score = 280 bits (715), Expect = 1e-74
Identities = 197/568 (34%), Positives = 285/568 (49%), Gaps = 88/568 (15%)
Query: 145 LSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSV 204
LS R ++ ++K++ + G+V R+S V P+++R+ GH + SV
Sbjct: 141 LSIRNIDPNDIDKIVQISGMVIRSSSVIPEIVRAFFRCSRCGHECLVE----------SV 190
Query: 205 PTPAIYPEEDQEGNKLVTE--YGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXX 262
P + + G K + + + D Q + +QE+PE P G P +
Sbjct: 191 RNVIDEPNKCECGGKYTQQLVHNASEFEDKQVVRIQELPEGIPNGTTPMAMTIVCRNEFV 250
Query: 263 XKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVS 322
PGDR+ + GV K+ N S FR +Y L S V
Sbjct: 251 DGLVPGDRVKLTGVLKATPV-------RLNPVMRKIKSTFR-------IY-LDLLSYQVI 295
Query: 323 AVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGS 382
+ S + I I++L ++++ L+ S+APS+ G E KKA++L L GGV K L S
Sbjct: 296 NRKIESSDPIDKIDELRKRPDVYEILANSVAPSVCGMEDTKKALVLQLFGGVRKEL-GSS 354
Query: 383 HLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRL 442
LRGDINIL+ GDP +KSQ+L F+ T+ + T+GRGSS VGLTA+V D +TG+ L
Sbjct: 355 RLRGDINILLAGDPGISKSQLLSFIHRTSERGMYTSGRGSSAVGLTASVAKDPDTGQFIL 414
Query: 443 EAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAAN 502
E+GA+VL+D GI CIDEFDKMSD R +HEVMEQQTV++AKAGI TTLNARCS++A+ N
Sbjct: 415 ESGALVLSDNGICCIDEFDKMSDSTRSVLHEVMEQQTVSVAKAGIITTLNARCSILASCN 474
Query: 503 PVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYL 562
P+ +Y+ K +NI LP +LLSRFD++ ++ D ++ DR I +H++ Y
Sbjct: 475 PIESKYNPRKSIVENINLPPTLLSRFDVVCLMIDRCDEFYDRTIGDHIVSL-------YS 527
Query: 563 EGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQI 622
E +E I+ LL A + A
Sbjct: 528 EETQRKEYIDAD-------------------------LLKAYVREA-------------- 548
Query: 623 VAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQNTKKSPITARTLETLIRLSS 682
R+ + + LTQ VD LR N K T R LE+LIRLS
Sbjct: 549 ------RRIVPRLTPESMKMLTQSYVD--------LRQMDNGKTITATTRQLESLIRLSE 594
Query: 683 AHAKVRLSKKVELEDAKVATQLLRFALL 710
AHA++R S VE +D + A +++R +LL
Sbjct: 595 AHARMRFSNAVEAKDVREAVRIIRESLL 622
>At2g16440 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 720
Score = 280 bits (715), Expect = 1e-74
Identities = 162/420 (38%), Positives = 245/420 (57%), Gaps = 23/420 (5%)
Query: 144 SLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXS 203
S S R LN + + K+IS++G++ R+S + P++ +V G+ + D
Sbjct: 136 STSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGY-----FSDPIIVDRGK 190
Query: 204 VPTP-AIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXX 262
+ P +E N + + C + D Q + +QE P++ P G P +
Sbjct: 191 ISEPPTCLKQECMTKNSMTLVHNRCRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLV 250
Query: 263 XKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVS 322
KPGDRI + G+Y+++ G ++ K S F+T + + ++ A +S
Sbjct: 251 DNGKPGDRIEVTGIYRAMTVR--VGPAHRTVK-----SVFKTYI--DCLHIKKASKLRMS 301
Query: 323 AVETLS--------DNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGV 374
A + + D D+R +LS +I++ LS+SLAP+I+ + +KK +L L GG
Sbjct: 302 AEDPMDVDNSLRRVDEDLRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGN 361
Query: 375 EKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTD 434
NL +G++ RGDINIL+VGDP T+KSQ+L+++ + I T+GRGSS VGLTA V D
Sbjct: 362 ALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKD 421
Query: 435 KETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNAR 494
ETGE LE+GA+VL+DRGI CIDEFDKMSD R +HEVMEQQTV+IAKAGI +LNAR
Sbjct: 422 PETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNAR 481
Query: 495 CSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTH 554
SV+A ANP +Y+ +NI LP +LLSRFDL++++ D ++ DR +++H++ H
Sbjct: 482 TSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALH 541
Score = 55.8 bits (133), Expect = 3e-07
Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 5/94 (5%)
Query: 621 QIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND---QNTKKSPITA--RTLE 675
+ + I + Y+ YA++ I P+L+ EA + + + Y LR + K ITA R +E
Sbjct: 551 EAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGKFAGSSKKVITATPRQIE 610
Query: 676 TLIRLSSAHAKVRLSKKVELEDAKVATQLLRFAL 709
+LIRLS A A++R S+ VE D A +LLR A+
Sbjct: 611 SLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAM 644
>ECU05g0780 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 726
Score = 273 bits (697), Expect = 1e-72
Identities = 199/585 (34%), Positives = 290/585 (49%), Gaps = 86/585 (14%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R L S L +L+S G VTRT+ VRP+L+ + G +++ P
Sbjct: 113 RELKSNRLGQLLSFSGTVTRTTQVRPELVSGTFVCKICGSVIDNVFQE------FKYTEP 166
Query: 208 AIYPEEDQEGNKL-VTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTK 266
P +L + +++ QRI VQE E+ PPG LPRS K +
Sbjct: 167 LTCPNHLCTNRRLWKLDIDKSKFLNWQRIHVQENTEEIPPGSLPRSMDVIVRNDLVEKIR 226
Query: 267 PGDRINIVGVY------------KSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPL 314
GD++ + G +S +G S+ K + + + +
Sbjct: 227 AGDKVVMTGYLIVVPDVVQLMMPQSKSVPMQSGESDEIRKKRNI--NIKDLNHKLSFMCI 284
Query: 315 HARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGV 374
HA V E ++ ++ I+++ +++ LSQS+ PSI+GH IK AILL+L+GGV
Sbjct: 285 HA-GCSVEEDEEFTNEELATISEMRSTPDLYYKLSQSMFPSIHGHYSIKNAILLLLVGGV 343
Query: 375 EKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTD 434
K G+ LRGDIN+L+VGDP TAKSQ L+ ++ T+G+ SS GLTA+V D
Sbjct: 344 GKRAEGGTRLRGDINMLLVGDPGTAKSQFLKQASAFLPRSVYTSGKSSSAAGLTASVVKD 403
Query: 435 KETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNAR 494
ETGE +EAGA++L+D G+ CIDEFDKM+ D+V+IHE MEQQT+TI+KAGI+ TLNAR
Sbjct: 404 GETGEFTIEAGALMLSDTGVCCIDEFDKMNVKDQVSIHEAMEQQTITISKAGINATLNAR 463
Query: 495 CSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTH 554
S++AAANP+ G+YD K +NI L ++SRFDL FV+ DD + DR ++ HVL +H
Sbjct: 464 SSILAAANPIKGRYDKKKTLRQNINLSAPVMSRFDLYFVLIDDADPENDRNVATHVLNSH 523
Query: 555 RYL-PPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGD 613
+ G L REQ+ L L K P + A AK
Sbjct: 524 ASVTDSGVLASYFTREQVKLYLRYA----------------RKKTPRMTAEAK------- 560
Query: 614 SNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQ--NTKKSPITA 671
+++IK Y +R D ++ +T
Sbjct: 561 -----------------------------------EMLIKRYVGIRQDSLIHSNNYMMTV 585
Query: 672 RTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALL---GED 713
R LE+LIRLS A AKV + V E + A +L++ +++ GED
Sbjct: 586 RHLESLIRLSEALAKVHDNDLVTKEYVEEAHRLVKSSVVEVKGED 630
>SPBC211.04c [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 892
Score = 272 bits (696), Expect = 2e-72
Identities = 167/451 (37%), Positives = 239/451 (52%), Gaps = 55/451 (12%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R L + + +L ++ G VTRTS VRP+L + + +V
Sbjct: 199 RDLRTDRIGRLTTITGTVTRTSEVRPELAQGTFICEEC------------HTVVSNVEQA 246
Query: 208 AIYPEEDQEGNKLVTE-------YGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXX 260
Y E Q N+L + D Q++ +QE + P G +PR+
Sbjct: 247 FRYTEPTQCPNELCANKRSWRLNISQSSFQDWQKVRIQENSNEIPTGSMPRTLDVILRGD 306
Query: 261 XXXKTKPGDRINIVGVY------KSLGAGGLTGGSNNNDKGNGA-----LSGFRTVVIGN 309
+ K GD+ G+ LG G+ + + + G ++G +++ + +
Sbjct: 307 IVERAKAGDKCAFTGILIAVPDVSQLGIPGVKPEAYRDSRNFGGRDADGVTGLKSLGVRD 366
Query: 310 TVYPLH------------------ARSTGVSAVE-------TLSDNDIRNINKLSMHDNI 344
Y L R G +E +LS +I ++ + D+I
Sbjct: 367 LTYKLSFLACMVQPDDANDKSGADVRGDGSQGIEEQDEFLQSLSQEEIDDLRAMVHSDHI 426
Query: 345 FDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQML 404
+ L+ SLAPS+YGHE IKK ILL LMGGV K P G +LRGD+NI +VGDPST+KSQ L
Sbjct: 427 YSRLTNSLAPSVYGHEIIKKGILLQLMGGVHKLTPEGINLRGDLNICIVGDPSTSKSQFL 486
Query: 405 RFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMS 464
++V N AI T+G+ SS GLTAAV D+ETG+ +EAGA++LAD GI IDEFDKM
Sbjct: 487 KYVCNFLPRAIYTSGKASSAAGLTAAVVKDEETGDFTIEAGALMLADNGICAIDEFDKMD 546
Query: 465 DVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSL 524
D+VAIHE MEQQT++IAKAGI TLNAR S++AAANP+ G+Y+ NI + +
Sbjct: 547 LSDQVAIHEAMEQQTISIAKAGIQATLNARTSILAAANPIGGRYNRKTTLRNNINMSAPI 606
Query: 525 LSRFDLLFVVTDDINDIRDRAISEHVLRTHR 555
+SRFDL FVV D+ N+ DR +++H++ HR
Sbjct: 607 MSRFDLFFVVLDECNESVDRHLAKHIVDIHR 637
>ECU04g0850 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 780
Score = 272 bits (695), Expect = 2e-72
Identities = 193/570 (33%), Positives = 288/570 (49%), Gaps = 85/570 (14%)
Query: 146 SPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVP 205
S R+L + HL KL+ V G+VTR S V P L V ++ + + P
Sbjct: 201 SVRSLRNRHLGKLVRVSGVVTRRSGVFP-LYSIVKFSCLKCRSVFGPF-----VASSFKP 254
Query: 206 TPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKT 265
T E Q Y D Q++T+QE+P PPG LPRS
Sbjct: 255 THCF---ECQSKGPFTVNTSETVYKDFQKLTIQEIPGSVPPGSLPRSKEVLLFYDLIDCA 311
Query: 266 KPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVE 325
KPG+ + + GVYK NN + +GF TV + +E
Sbjct: 312 KPGEEVEVTGVYK-----------NNFNVSLNIRNGFPVFF---TVIEASSVVKRAGKIE 357
Query: 326 TLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSH-L 384
++D+D+R I K+ H I + S+APS+YGH +K+AI L ++GGV + + SH +
Sbjct: 358 -MTDDDVREIKKMGRHPEIKRIVINSIAPSVYGHAEVKRAIALAMLGGVARE--STSHRI 414
Query: 385 RGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEA 444
RGDIN+L++GDP AKSQ LR+V +T+ A+ TG+G+S VGLTA+V D E LE
Sbjct: 415 RGDINVLLLGDPGMAKSQFLRYVESTSHRAVLATGQGASSVGLTASVRKDPVVKEWTLEG 474
Query: 445 GAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPV 504
GA+VLAD+GI IDEFDKM++ DR +IHE MEQQ+++I+KAGI TL+ARCSVIAAANP+
Sbjct: 475 GALVLADKGICLIDEFDKMNEHDRTSIHEAMEQQSISISKAGIVATLHARCSVIAAANPM 534
Query: 505 FGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTH---RYLPPGY 561
G+Y+ + +N+ L D ++SRFD+L VV D I+ D ++ V+ +H P G+
Sbjct: 535 RGRYNGSLTFAQNVNLSDPIISRFDILCVVKDAIDAGEDEKTAKFVIESHEGGEEKPDGF 594
Query: 562 LEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQ 621
+P R + L K+ +L+A + D + ++
Sbjct: 595 ---DPKRMMMGHEL------------------LRKY--ILYARTNVVPAFNDVDMEKISS 631
Query: 622 IVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQNTKKSPITARTLETLIRLS 681
+ Y++ KE + L P+T R +E+++R+S
Sbjct: 632 L--------YLELRKESLPSGL------------------------PVTVRHVESIVRIS 659
Query: 682 SAHAKVRLSKKVELEDAKVATQLLRFALLG 711
A AK+RLS+ V +ED A ++ + +G
Sbjct: 660 EAFAKMRLSRVVSVEDIDEAISVVLDSFMG 689
>YGL201c [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 1017
Score = 268 bits (686), Expect = 2e-71
Identities = 164/465 (35%), Positives = 241/465 (51%), Gaps = 64/465 (13%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R + S + L+S+ G VTRTS VRP+L ++ R D P
Sbjct: 277 RDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMC-----RAIVD-NVEQSFKYTEP 330
Query: 208 AIYPEEDQEGNKLVT-EYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTK 266
P E T ++D Q++ +QE + P G +PR+ + K
Sbjct: 331 TFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAK 390
Query: 267 PGDRINIVGV------YKSLGAGGLTGGSNNNDKG--------NGALSGFRTVVIGNTVY 312
PGDR GV LG G+ S + +G N ++G R++ + + Y
Sbjct: 391 PGDRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTTEGLNSGVTGLRSLGVRDLTY 450
Query: 313 PL-----HARSTGVSA--------------------------------------VETLSD 329
+ H S G + + +LS
Sbjct: 451 KISFLACHVISIGSNIGASSPDANSNNRETELQMAANLQANNVYQDNERDQEVFLNSLSS 510
Query: 330 NDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDIN 389
++I + ++ ++I+D L +S+AP+++GHE +KK ILL ++GGV K+ G LRGDIN
Sbjct: 511 DEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDIN 570
Query: 390 ILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVL 449
I +VGDPST+KSQ L++V+ A ++ T+G+ SS GLTAAV D+E G+ +EAGA++L
Sbjct: 571 ICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALML 630
Query: 450 ADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYD 509
AD GI CIDEFDKM D+VAIHE MEQQT++IAKAGIH TLNAR S++AAANPV G+Y+
Sbjct: 631 ADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYN 690
Query: 510 VNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTH 554
N+ + ++SRFDL FV+ DD N+ D ++ H++ H
Sbjct: 691 RKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH 735
>ECU06g0340 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 696
Score = 268 bits (684), Expect = 4e-71
Identities = 212/663 (31%), Positives = 316/663 (46%), Gaps = 109/663 (16%)
Query: 63 MDHDTNQLPLRITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVS--ETAMALDDSPLG 120
+ + NQ +TV L+ + ++ L + P ERA+ E A+A + G
Sbjct: 47 LSSNINQDNFSLTVKLEHIYQYSDLLSRELSRRP-------ERAIEWFEEAVADRYNVKG 99
Query: 121 FRGFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLV--RPKLLRS 178
+GFQ R + R +N++ NK++ ++GIV S V +P+ L
Sbjct: 100 VQGFQLCLVSDGRC----------IPIREINASKTNKIVKIQGIVVSASSVITKPRTLFL 149
Query: 179 VHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIY-PEEDQEGNKLVTEYGFCHYMDHQRITV 237
V D P P I PE+ Q +D Q + +
Sbjct: 150 V-CRNCLSSKEVMDMIPRMCDKTECPPDPYIVIPEKSQ-------------VIDVQYVKI 195
Query: 238 QEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVY--KSLGAGGLTGGSNNNDKG 295
QE E P G+ PR + PG ++ I G+Y + + L
Sbjct: 196 QEFFEDIPVGETPRHFSLVLEKKMVNRLIPGSKVVITGIYCMRMIRDSSLP--------- 246
Query: 296 NGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPS 355
V+G L RS S + T + + + KLS D I++ +S+S+APS
Sbjct: 247 -------IVKVVG-----LEDRSLKTSKMFTEEEEE--SFKKLSKAD-IYERISRSIAPS 291
Query: 356 IYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAI 415
+YGHE +K+A+ ML GG + L + LRGDIN+L++GDP AKSQ+L+F+ + + +
Sbjct: 292 VYGHEDVKRALACMLFGGTRRVLEDKVTLRGDINVLLLGDPGMAKSQLLKFMELVSPVGV 351
Query: 416 ATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVM 475
T+G+GSS GLTA+V D GE LE GA+VLAD GI CIDEFDKM + DRVAIHE M
Sbjct: 352 YTSGKGSSAAGLTASVIRDSG-GEFYLEGGALVLADNGICCIDEFDKMDEHDRVAIHEAM 410
Query: 476 EQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVT 535
EQQT++IAKAGI T LN R S++AAANPVFG+YD K P +NI ++LSRFD +F++
Sbjct: 411 EQQTISIAKAGITTMLNTRTSILAAANPVFGRYDDYKTPDENIEFGATILSRFDCIFILK 470
Query: 536 DDINDIRDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFE 595
D + D +++HVL H+ RE
Sbjct: 471 DK-HGPNDIILAKHVLSVHQ---------NKAREDNE----------------------- 497
Query: 596 KFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSY 655
G + S P I+ I I++Y+QYA+ ++ P L++ A + + Y
Sbjct: 498 -----CQNGLHDDQEEQISGSDRSPDIIPIHTIKRYVQYARSKVFPTLSEAASKQLSRYY 552
Query: 656 SNLRN-----DQNTKKS---PITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRF 707
N R +Q+T K PIT R LE +IR+ + AK+ LS+ V + + A +L +
Sbjct: 553 VNTRKEVRQLEQSTLKRNAIPITVRQLEAIIRIGESLAKMELSQIVTEKHVEEAIRLFKV 612
Query: 708 ALL 710
+ +
Sbjct: 613 STM 615
>HsM14149623 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 543
Score = 267 bits (682), Expect = 6e-71
Identities = 144/354 (40%), Positives = 219/354 (61%), Gaps = 15/354 (4%)
Query: 212 EEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRI 271
+ ++ G +L + ++ Q + +QE ++ P G +PRS +PGD +
Sbjct: 36 QTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHV 95
Query: 272 NIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDND 331
++ G++ + G G LS T + + + ++ S L+ +
Sbjct: 96 SVTGIFLPILRTGF------RQVVQGLLS--ETYLEAHRIVKMNKSEDDESGAGELTREE 147
Query: 332 IRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINIL 391
+R I + ++ ++ L+ S+AP IYGHE +KKA+LL+L+GGV+++ P G +RG+INI
Sbjct: 148 LRQIAE----EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINIC 202
Query: 392 MVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLAD 451
++GDP AKSQ+L ++ A + TTGRGSSGVGLTAAV D +GE LE GA+VLAD
Sbjct: 203 LMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLAD 262
Query: 452 RGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVN 511
+G+ CIDEFDKM++ DR AIHEVMEQQT++IAKAGI TTLNARCS++AAANP +G+Y+
Sbjct: 263 QGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPR 322
Query: 512 KDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRY--LPPGYLE 563
+ +NI LP +LLSRFDLL+++ D + D +++H+ H++ PP E
Sbjct: 323 RSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE 376
>CE09874 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 730
Score = 265 bits (676), Expect = 3e-70
Identities = 156/417 (37%), Positives = 231/417 (54%), Gaps = 35/417 (8%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R + +T + L+S++G+V R + V+P + + T Y+ + + P
Sbjct: 163 RNIKATEIGHLVSMKGVVIRATEVKPCVEVMTYTCDTCAAEVYQPVKGMQFTPPVNCPNK 222
Query: 208 AIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKP 267
E + +L + ++ Q + +QE+ E+ P G +PR+ K
Sbjct: 223 ECV--EAKANGRLHMQLRGSKFVKFQELKIQELSEQVPVGSIPRTMTVHVYGEMTRKCNT 280
Query: 268 GDRINIVGVYKSLGAGGL--TGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVE 325
G+ +++ GV+ + G TGG ++ +T H +
Sbjct: 281 GNVVHVSGVFLPIMQSGFRPTGG-----------------LVADTYLEAHY-------IN 316
Query: 326 TLSDNDIRN------INKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLP 379
L DN N + L + ++TL+ S+AP I+GH +KK +L+ L+GG + N
Sbjct: 317 NLDDNPTFNGVQSAELEVLRRKGDNYETLAASIAPEIFGHVDVKKCLLMALVGGND-NSS 375
Query: 380 NGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGE 439
NG +RG IN+LM+GDP AKSQ+L +V A + TTGRGSSGVGLTAAV D TGE
Sbjct: 376 NGMKIRGCINVLMMGDPGVAKSQLLGYVNRLAPRSQYTTGRGSSGVGLTAAVMKDPVTGE 435
Query: 440 RRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIA 499
LE GA+VLAD GI CIDEFDKM D DR AIHEVMEQQT++IAKAGI TTLNAR ++IA
Sbjct: 436 MSLEGGALVLADGGICCIDEFDKMMDHDRTAIHEVMEQQTISIAKAGIMTTLNARTAIIA 495
Query: 500 AANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRY 556
AANP +G+Y+ N+ +N+ LP +LLSRFDL+ ++ D + D+ ++EH+ H++
Sbjct: 496 AANPAYGRYNPNRSIEQNVDLPAALLSRFDLILLMQDKADRENDKILAEHITYVHQH 552
>CE00415 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 810
Score = 258 bits (659), Expect = 3e-68
Identities = 156/441 (35%), Positives = 236/441 (53%), Gaps = 38/441 (8%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
R L++ + L+ + G + RT V P+L R+ + G RD + PT
Sbjct: 123 RELSADKVGGLVRIAGQIVRTHPVHPELSRACFVCEDCGV----TTRDVQQQFRYTQPTK 178
Query: 208 AIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKP 267
P+ + + ++D Q+I +QE + P G +PR+ +P
Sbjct: 179 CANPQ-CMNRTRFSLDVNSSTFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQP 237
Query: 268 GDRINIVGVY------KSLGAGGLTGGSNNNDKGNGA-----LSGFRTVVIGNTVYPLHA 316
GD+ +IVG L GL ++N ++G ++G + + + + Y +
Sbjct: 238 GDKCDIVGTLIVIPDIAQLSTPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAF 297
Query: 317 RSTGVSAVETL---------------------SDNDIRNINKLSMHDNIFDTLSQSLAPS 355
+ + E+L S D + K+S I + SL P+
Sbjct: 298 LACHIQQTESLVGGDASGAVEETDYLDLWSKMSTEDRATLKKMSDDKKIEKNIVDSLFPN 357
Query: 356 IYGHEHIKKAILLMLMGGV-EKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALA 414
IYG+ +K +LLML+GGV +K+ G+ LRGDIN+ +VGDPSTAKSQ+L+ V + A
Sbjct: 358 IYGNHEVKLGVLLMLLGGVAKKSRDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEFSPRA 417
Query: 415 IATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEV 474
I T+G+ SS GLTAAV D+E+ E +EAGA++LAD G+ CIDEFDKM D+VAIHE
Sbjct: 418 IYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEA 477
Query: 475 MEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVV 534
MEQQT++I KAG+ TLNAR S++AAANPV G+YD ++ N+ + ++SRFDL FV+
Sbjct: 478 MEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLKYNVQMSAPIMSRFDLFFVL 537
Query: 535 TDDINDIRDRAISEHVLRTHR 555
D+ N++ D AI+ +L HR
Sbjct: 538 VDECNEVTDYAIARRILDNHR 558
>YBR202w [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 845
Score = 258 bits (658), Expect = 4e-68
Identities = 158/457 (34%), Positives = 243/457 (52%), Gaps = 33/457 (7%)
Query: 119 LGFRGFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRS 178
L F+ + +R++R K + LS R + L +LI+V GI+TR S V+P +
Sbjct: 202 LYFKPLSQNCARRYR---KKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVI 258
Query: 179 VHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQ 238
+ G+ +++ + ++Q +L + Q +Q
Sbjct: 259 AYTCDQCGYEVFQEVNSRTFTPLSECTSEEC--SQNQTKGQLFMSTRASKFSAFQECKIQ 316
Query: 239 EMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVY--------KSLGAGGLTGGSN 290
E+ ++ P G +PRS PGD +++ G++ K+L AG LT
Sbjct: 317 ELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLT---- 372
Query: 291 NNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQ 350
T + V + S + + + +L ++++ L++
Sbjct: 373 ------------ETYLEAQFVRQHKKKFASFSLTSDVEER----VMELITSGDVYNRLAK 416
Query: 351 SLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNT 410
S+AP IYG+ +KKA+LL+L+GGV+K + +G +RGDIN+ ++GDP AKSQ+L+ +
Sbjct: 417 SIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKI 476
Query: 411 AALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVA 470
+ + TTG+GSSGVGLTAAV D T E LE GA+VLAD GI CIDEFDKM + DR A
Sbjct: 477 SPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTA 536
Query: 471 IHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDL 530
IHEVMEQQT++I+KA I+T AR S++AAANP++G+ + P NI LP +LLSRFD+
Sbjct: 537 IHEVMEQQTISISKAVINTNPGARTSILAAANPLYGRINPRLSPLDNINLPAALLSRFDI 596
Query: 531 LFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEPV 567
LF++ D + D ++EHV H + L+ PV
Sbjct: 597 LFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPV 633
>ECU09g1360 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 694
Score = 256 bits (653), Expect = 1e-67
Identities = 162/451 (35%), Positives = 236/451 (51%), Gaps = 49/451 (10%)
Query: 130 RQWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHH 189
R++ L K S R L S H+ L+ V G+VT+ S V+P + + + + G
Sbjct: 130 RRYSLVLKPRRNSRVYSVRGLKSMHIGSLVRVSGVVTKVSQVKPSIRVATYVCEGCGAET 189
Query: 190 YRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQL 249
Y++ + + LVT ++ HQ + +QE+ P G +
Sbjct: 190 YQEVDGDVFDLLEECGSEKCRIRNVRGTLVLVTRGS--KFIKHQTVYMQELTGDIPRGCI 247
Query: 250 PRSXXXXXXXXXXXKTKPGDRINIVGVY--------KSLGAGGLTG----GSNNNDKGNG 297
PR+ K +PGD + + GV+ K L AG L +N G G
Sbjct: 248 PRTLVAECYSSMAEKCRPGDVVVVGGVFMPKPYHGIKKLKAGLLADIYLHATNIEKIGAG 307
Query: 298 ALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIY 357
A G V YP+ + + +S+AP I+
Sbjct: 308 APKGNEEV----KAYPV-------------------------------EQMVRSIAPEIF 332
Query: 358 GHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIAT 417
G E IKK +LLML+G + +G +RGDIN+L+VGDP AKSQ+L+ + + T
Sbjct: 333 GMEDIKKILLLMLIGAPGRVREDGMKIRGDINVLLVGDPGIAKSQLLKTCVKIGRRGVYT 392
Query: 418 TGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQ 477
TG+GSSGVGLTA+V+ D TGE LE GA+VLAD GI CIDE DKM++VDRV+IHEVMEQ
Sbjct: 393 TGKGSSGVGLTASVSKDPITGEMVLEGGALVLADGGICCIDELDKMNEVDRVSIHEVMEQ 452
Query: 478 QTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDD 537
Q+V+I+KAGI+T+LNARC V+ AANPV G+YD + NI LP +LLSRFD++ ++ D+
Sbjct: 453 QSVSISKAGINTSLNARCCVLGAANPVKGKYDTRQSIEHNIGLPCALLSRFDVVAILRDE 512
Query: 538 INDIRDRAISEHVLRTHRYLPPGYLEGEPVR 568
N +D +++ H+ H + P + + +R
Sbjct: 513 PNLEKDESLANHITSIHLHEEPESIPYDKIR 543
>7290738 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 817
Score = 252 bits (644), Expect = 2e-66
Identities = 209/709 (29%), Positives = 324/709 (45%), Gaps = 121/709 (17%)
Query: 45 VKEKKTDDDYLNTADKD-----TMDHDTNQLPLRIT--VSLDDLREFDKTFWTGLLQVPS 97
++ +K D+L +D T + + P R T VS +D+ ++D+ T +++
Sbjct: 19 IRAQKLFQDFLEEFKEDGEIKYTRPAASLESPDRCTLEVSFEDVEKYDQNLATAIIEEYY 78
Query: 98 FFLPPAERAVS---ETAMALDDSPLGFRGFQNDPSRQWRLSFKGSFGPNSLSPRTLNSTH 154
P ++VS + + L + F P+R R L ++
Sbjct: 79 HIYPFLCQSVSNYVKDRIGLKTQKDCYVAFTEVPTRH--------------KVRDLTTSK 124
Query: 155 LNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTPAIYPEED 214
+ LI + G V RT V P+L+ V + R+ + PT P
Sbjct: 125 IGTLIRISGQVVRTHPVHPELVSGVFMCLDC----QTEIRNVEQQFKFTNPTICRNPVCS 180
Query: 215 QEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIV 274
+ + + ++D Q+I +QE + P G +PR+ + GDR +
Sbjct: 181 NR-KRFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFT 239
Query: 275 G-------VYKSLGAGGLTGGSNNNDKGNG--ALSGFR---------------------T 304
G V G G S+ + G G ++G + T
Sbjct: 240 GTLIVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATT 299
Query: 305 VVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKK 364
G T P+ + T + ++D + I ++S N++ L SL PSIYG++ +K+
Sbjct: 300 ARFGGTDLPM-SEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKR 358
Query: 365 AILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSG 424
ILL GGV K + LRGDIN+ +VGDPSTAKSQ L+ V + + AI T+G+ SS
Sbjct: 359 GILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSA 418
Query: 425 VGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAK 484
GLTAAV D+E+ + +EAGA++LAD GI CIDEFDKM D+VAIHE MEQQT++IA+
Sbjct: 419 AGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIAR 478
Query: 485 AGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDR 544
AG+ TLNAR S++AAANP+ G+YD +K +NI L ++SRFDL F++ D+ N++ D
Sbjct: 479 AGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDY 538
Query: 545 AISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVF-EKFNPLL-- 601
AI+ ++ H + +E RE++ V F +F P++
Sbjct: 539 AIARKIVDLHSNIEES-VERAYTREEV-----------------LRYVTFARQFKPVISQ 580
Query: 602 HAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRND 661
AG L +N G + ++R D S R
Sbjct: 581 EAGHMLVENYG---------------------HLRQR----------DTGTSGRSTWR-- 607
Query: 662 QNTKKSPITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALL 710
IT R LE++IRLS A AK+ S +V K A +LL +++
Sbjct: 608 -------ITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNKSII 649
>Hs7427519 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 821
Score = 248 bits (634), Expect = 2e-65
Identities = 169/518 (32%), Positives = 253/518 (48%), Gaps = 59/518 (11%)
Query: 74 ITVSLDDLREFDKTFWTGLLQVPSFFLPPAERAVSETAMALDDSPLG---FRGFQNDPSR 130
+ VS DL +F++ T + + P RA+ + PL + FQ+ P+R
Sbjct: 61 LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR 120
Query: 131 QWRLSFKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYA---QTTGH 187
R L S+ + L + G V RT V P+L+ QT
Sbjct: 121 H--------------KIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTV-- 164
Query: 188 HHYRDYRDAXXXXXXSVPTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPG 247
RD + P P + + + ++D Q++ +QE + P G
Sbjct: 165 -----IRDVEQQFKYTQPNICRNPVCANR-RRFLLDTNKSRFVDFQKVRIQETQAELPRG 218
Query: 248 QLPRSXXXXXXXXXXXKTKPGDRINIVGVY---------KSLGA--------GGLTGGSN 290
+PRS + GD+ + G + GA G+ G
Sbjct: 219 SIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYET 278
Query: 291 NNDKGNGALS----GFRTVVIGNTVYPLHAR----------STGVSAVETLSDNDIRNIN 336
+G AL +R V + V P + R T S ++ + +
Sbjct: 279 EGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVF 338
Query: 337 KLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDP 396
++S N++ L SL P+I+G++ +K+ +LLML GGV K G+ LRGDIN+ +VGDP
Sbjct: 339 EMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDP 398
Query: 397 STAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVC 456
STAKSQ L+ V + A+ T+G+ SS GLTAAV D+E+ E +EAGA++LAD G+ C
Sbjct: 399 STAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCC 458
Query: 457 IDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHK 516
IDEFDKM D+VAIHE MEQQT++I KAG+ TLNAR S++AAANP+ G YD +K +
Sbjct: 459 IDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQ 518
Query: 517 NIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTH 554
NI L ++SRFDL F++ D+ N++ D AI+ ++ H
Sbjct: 519 NINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLH 556
>Hs19923727 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 840
Score = 246 bits (629), Expect = 9e-65
Identities = 184/589 (31%), Positives = 283/589 (47%), Gaps = 49/589 (8%)
Query: 148 RTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSVPTP 207
+ + + + K I++ G V R S ++P + G D S+PT
Sbjct: 208 KNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKY----SLPTK 263
Query: 208 AIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEM--PEKAPPGQLPRSXXXXXXXXXXXKT 265
P + MD Q I +QE+ ++ G++PR+
Sbjct: 264 CPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSC 323
Query: 266 KPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSA-- 323
PGD + I G+ K A G N NDK F + N++ + T S
Sbjct: 324 VPGDTVTITGIVKVSNAE--EGSRNKNDK-----CMFLLYIEANSISNSKGQKTKSSEDG 376
Query: 324 -----VETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNL 378
+ S D+ I ++ +N+F + SL P I+GHE +K + L L GG +K
Sbjct: 377 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 436
Query: 379 PNGSHL--RGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKE 436
+ + + RGD +IL+VGDP KSQML+ N A + G ++ GLT ++ D
Sbjct: 437 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 496
Query: 437 TGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCS 496
+G+ LEAGA+VL D+GI IDEFDKM + + A+ E MEQQ++++AKAG+ +L AR S
Sbjct: 497 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTS 555
Query: 497 VIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTHRY 556
+IAAANPV G Y+ K +N+ + +LLSRFDL+F++ D N+ D +SEHV+
Sbjct: 556 IIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAI--- 612
Query: 557 LPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSNG 616
+++ S V VV EK PL +L G++
Sbjct: 613 --------RAGKQRTISSATVARMNSQDSNTSVLEVVSEK--PL---SERLKVVPGET-- 657
Query: 617 SELPQIVAIP--FIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLR-NDQNTKKSPITART 673
I IP +RKYI YA++ + P+L+ EA V+ Y LR Q SPIT R
Sbjct: 658 -----IDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQ 712
Query: 674 LETLIRLSSAHAKVRLSKKVELEDAKVATQLLRFALLGEDGANFDEQEF 722
LE+LIRL+ A A++ L ++ EDA+ +++++++LG F +F
Sbjct: 713 LESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDF 761
>7304207 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 866
Score = 244 bits (624), Expect = 3e-64
Identities = 162/481 (33%), Positives = 252/481 (51%), Gaps = 39/481 (8%)
Query: 81 LREFDKTFWTGLLQVPSFFLPPAERAVSETAM-----ALDDSPLGFRGFQNDPSRQWRLS 135
L+ FD+ + L+ P +P + A++E AL + + R F D +R R
Sbjct: 218 LKTFDQDLYRQLICYPQEVIPGFDMAINEMFFERYPAALLEHQIQVRPFNADKTRNMR-- 275
Query: 136 FKGSFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRD 195
+LN +++LIS+ G+V R+S V P++ + +
Sbjct: 276 -------------SLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICS------FST 316
Query: 196 AXXXXXXSVPTPAIYPE-EDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXX 254
+ P + +L+ + + D Q + +QE P+ GQ P +
Sbjct: 317 TVEVDRGRINQPTLCTNCNTNHCFRLI--HNRSEFTDKQLVKLQESPDDMAAGQTPHNVL 374
Query: 255 XXXXXXXXXKTKPGDRINIVGVYKS--LGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVY 312
K +PGDR+ + G+Y++ L GGL+ + K + + FR V
Sbjct: 375 LYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVKSVYKTHVDVVHFRKVDNKR--- 431
Query: 313 PLHARSTGVSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMG 372
L+ G + + + L+ +I+D L++++APSIY ++ IKK ILL L G
Sbjct: 432 -LYEDEEGKDHI--FPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFG 488
Query: 373 GVEKNLPN--GSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAA 430
G +K + R +I++L+ GDP T+KSQML++V N + T+GRGSS VGLTA
Sbjct: 489 GTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAY 548
Query: 431 VTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTT 490
VT D ET + L+ GA+VLAD G+ CIDEFDKM+D R +HEVMEQQT++IAKAGI
Sbjct: 549 VTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQ 608
Query: 491 LNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHV 550
LNAR S++AAANP Q++ K+ N+ LP +LLSRFDL+F+V D ++I D+ ++ H+
Sbjct: 609 LNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHL 668
Query: 551 L 551
+
Sbjct: 669 V 669
Score = 63.9 bits (154), Expect = 1e-09
Identities = 40/84 (47%), Positives = 55/84 (64%), Gaps = 3/84 (3%)
Query: 628 IRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQNTKKSPITA--RTLETLIRLSSAHA 685
+R YI YA+E + P L+ EA +I++Y ++R + I+A R LE+LIRLS AHA
Sbjct: 689 LRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRK-VGAGRGQISAYPRQLESLIRLSEAHA 747
Query: 686 KVRLSKKVELEDAKVATQLLRFAL 709
KVRLS +VEL D + A +L R AL
Sbjct: 748 KVRLSNQVELLDVEEAWRLHREAL 771
>At3g09660 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 777
Score = 211 bits (538), Expect = 3e-54
Identities = 145/437 (33%), Positives = 223/437 (50%), Gaps = 26/437 (5%)
Query: 139 SFGPNSLSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXX 198
++ +S+S + L + ++ KL++V G V + S V+P + + R++ D
Sbjct: 137 NYPESSISLKNLRAAYIGKLVTVHGTVVKVSTVKPLVTQMAFDCGKCKTGITREFTDGKF 196
Query: 199 XXXXSVPTPAIYPEEDQEGNKLVTEY-GFCHYMDHQRITVQEM--PEKAPPGQLPRSXXX 255
+P + + +K T +D Q+I VQE+ PE G++PR+
Sbjct: 197 -------SPPLKCDSHGCKSKTFTPIRSSAQTIDFQKIRVQELQKPEDHEEGRVPRTVEC 249
Query: 256 XXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGF-RTVVIGNTVYPL 314
PGD + + G+ + GG + K G F V + NT
Sbjct: 250 ELMEDLVDICIPGDVVTVTGIIGVINNYMDIGGGKSKTKNQGFYYLFIEAVSVKNTKRQS 309
Query: 315 ----------HARSTGVSAVETLSDNDIRNINKLSMH--DNIFDTLSQSLAPSIYGHEHI 362
A++ V + + S D+ I K + F + S+ PSIYGHE +
Sbjct: 310 AFENSEDSSSSAQTADVGDLYSFSQRDLEFIVKFKEEYGSDTFRRILHSVCPSIYGHEIV 369
Query: 363 KKAILLMLMGGVEKNLP--NGSHLRGDINILMVGDPSTAKSQMLRFVLNTAALAIATTGR 420
K I L L GGV K+ N +RGDI++++VGDP KSQ+L+ + I G
Sbjct: 370 KAGITLSLFGGVRKHSMDRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGN 429
Query: 421 GSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVDRVAIHEVMEQQTV 480
++ GLT AV D T + EAGAMVLAD G+ CIDEFDKM+ + A+ E MEQQ V
Sbjct: 430 ATTRAGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMT-TEHQALLEAMEQQCV 488
Query: 481 TIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSRFDLLFVVTDDIND 540
++AKAG+ +L+AR SVIAAANPV G Y+ K ++N+ + +LLSRFDL+F++ D ++
Sbjct: 489 SVAKAGLVASLSARTSVIAAANPVGGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDE 548
Query: 541 IRDRAISEHVLRTHRYL 557
+ D+ +SEH++ HR L
Sbjct: 549 LLDKQVSEHIMSHHRML 565
>ECU11g0800 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 681
Score = 189 bits (480), Expect = 2e-47
Identities = 145/489 (29%), Positives = 228/489 (45%), Gaps = 64/489 (13%)
Query: 229 YMDHQRITVQEM--PEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLT 286
Y D Q I +QE+ + +P++ PGD + IVGV
Sbjct: 185 YRDVQEIKIQELYGGSEGDGNGIPKAVDCILYDEFAGTLAPGDIVEIVGVL--------- 235
Query: 287 GGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIFD 346
G ND + ++ V N + + ++ V VE S D K++ N
Sbjct: 236 GVELEND------NLYKLTVHINNLQIVKNKNFFVEDVEYQS-RDFAEFRKIAGAGNTLA 288
Query: 347 TLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSH-LRGDINILMVGDPSTAKSQMLR 405
+L SL ++YG+E IK ++L L GG +K+ G H +R + ++L+VGDP KS++L
Sbjct: 289 SLVCSLYSAVYGNELIKVGLVLSLFGGTKKSA--GQHSIRSETHVLIVGDPGLGKSRLLL 346
Query: 406 FVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSD 465
+ +G ++ GLT ++T D +GE +AGA+V+AD GI C+DEFDK+ D
Sbjct: 347 STCGILPKSSYVSGSFTTTAGLTVSLTHDPVSGEYMADAGALVVADNGICCLDEFDKIDD 406
Query: 466 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLL 525
A+ E ME Q V+IAK G+ ++ R +VIAA NP G +D K +NI LL
Sbjct: 407 --HAALFEAMEDQKVSIAKGGVICSVPTRATVIAATNPRHGHFDRGKTMAENIRFDPGLL 464
Query: 526 SRFDLLFVVTDDINDIRDRAISEHVLRTHRYLPPGYLEGEPVREQINLSLAVGXXXXXXX 585
SRFDL+F++ DD+++ IS +L+ R L PG + V E + + V
Sbjct: 465 SRFDLIFLLLDDLSEKESYMISGQILKKRRTLSPGEGGFDDVVETVRRDMFVEDIR---- 520
Query: 586 XXXXXXVVFEKFNPLLHAGAKLAKNRGDSNGSELPQIVAIPFIRKYIQYAKERIIPQLTQ 645
S G P + +RKYI YA+ + P L++
Sbjct: 521 ----------------------------SGGCVYP----MDIVRKYISYARANVFPVLSK 548
Query: 646 EAVDVIIKSYSNLRNDQNTKKSPITARTLETLIRLSSAHAKVRLSKKVELEDAKVATQLL 705
A + I + Y +R+ + ++ R LE+L+RL+ A AKV L DA +L
Sbjct: 549 SASEAIKEYYVGMRS-----RGGVSTRDLESLVRLTEARAKVELRSIATKADAMFCIELH 603
Query: 706 RFALLGEDG 714
+ + ++G
Sbjct: 604 KRTFVSKEG 612
>At2g14050 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 610
Score = 137 bits (345), Expect = 8e-32
Identities = 92/283 (32%), Positives = 141/283 (49%), Gaps = 23/283 (8%)
Query: 231 DHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXKTKPGDRINIVGVYKSLGAGGLTGGSN 290
D+Q I +QE + G +PRS K GD + + G+ S + L
Sbjct: 211 DYQEIKIQENTQVLGVGVIPRSILVVLKDDLVDNVKAGDDVVVSGILTSKWSHDL----- 265
Query: 291 NNDKGNGALSGFRTVVIGNTVYPLHARSTGVSAVETLSDNDIRNINKLSMHDNIF----- 345
++I N V R+ + + +SD+ I H
Sbjct: 266 -----KDVRCDLEPMLIANHV----RRTNELKSEIDISDDLIEKFKNFWSHFRDTPLKGR 316
Query: 346 DTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLR 405
+ + + + P ++G +K A+ L L+GGV+ +G+ +RG+ ++L++GDP T KSQ L+
Sbjct: 317 NAILRGICPQVFGLFTVKLAVALTLIGGVQHVDASGTKVRGESHLLLIGDPGTGKSQFLK 376
Query: 406 FVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSD 465
F + A+ TTG GS+ GLT VT K+ GE LEAGA+VLAD G+ CIDEFD M +
Sbjct: 377 FAAKLSNRAVITTGLGSTSAGLT--VTAVKDGGEWMLEAGALVLADGGLCCIDEFDSMRE 434
Query: 466 VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQY 508
DR IHE MEQQ++++AK I LN + + P + Q+
Sbjct: 435 HDRATIHEAMEQQSISVAK--IQKILNGMQLYLLTSLPRYIQF 475
>ECU07g0490 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 563
Score = 135 bits (341), Expect = 2e-31
Identities = 85/204 (41%), Positives = 120/204 (58%), Gaps = 4/204 (1%)
Query: 348 LSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFV 407
L S A I G E++K +LL L+ G S R + +IL+VGD T KS +L+
Sbjct: 224 LVNSFAEEIQGLENVKLGLLLALVSG-SHGADQKSGTRSNSHILLVGDSGTGKSHLLKTC 282
Query: 408 LNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGIVCIDEFDKMSDVD 467
+ A+ T G G++ GLT ++ E LEAGA+VLAD G+ CIDEF+K+ +
Sbjct: 283 SRLLSPAVLTNGVGTTQAGLTTCAV--RQGREWVLEAGALVLADTGLCCIDEFNKLKVNE 340
Query: 468 RVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNKDPHKNIALPDSLLSR 527
+ + E MEQQT++IAKAGI ++LN RCSVIAA N +Y NK +NI + L+SR
Sbjct: 341 KNGLLEAMEQQTLSIAKAGIVSSLNTRCSVIAAIN-TRHKYSFNKSISENIMVATPLISR 399
Query: 528 FDLLFVVTDDINDIRDRAISEHVL 551
FDL+F + DD + D I + +L
Sbjct: 400 FDLIFGLFDDRDGRSDLLIVDKIL 423
>7300061 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 755
Score = 116 bits (291), Expect = 1e-25
Identities = 93/348 (26%), Positives = 166/348 (46%), Gaps = 30/348 (8%)
Query: 328 SDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGD 387
S+ D+ I ++ N F L QS+AP +YGHE K A LL L+GG G+
Sbjct: 414 SERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGG------KGAETEA- 466
Query: 388 INILMVGDPSTAKSQMLRFVLNTAALAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAM 447
IN+L+VGDP K+++L+ A +G+ + VT +R L+AG++
Sbjct: 467 INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFAGRN-KRVLQAGSL 525
Query: 448 VLADRGIVC-IDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFG 506
++A G C +D+ DK++ V + + ++ + V + AG + A+ SVIA ANP G
Sbjct: 526 MMASGGGHCTLDDVDKLASKQAVLL-QCLQSEEVNLPLAGAFASFPAQPSVIACANPQRG 584
Query: 507 QYDVNKDPHKNIALPDSLLSRFDLLFVVTDDINDIRDRAISEHVLRTH-----------R 555
QYD + +NI + SLL F L++++ D ++ RD +++ HV H R
Sbjct: 585 QYDEGRYLLQNINISPSLLREFHLVYILLDKPSE-RDMSLTAHVRALHAGARKRARIAAR 643
Query: 556 YLPPGYLEGEPVREQINLSLAVGXXXXXXXXXXXXXVVFEKFNPLLHAGAKLAKNRGDSN 615
Y + +N+ A ++ + ++ L ++ GD +
Sbjct: 644 YALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYD--LDKRLEVLPEEGDLD 701
Query: 616 GSELPQIVAIPFIRKYIQYAKERIIPQLTQEAVDVIIKSYSNLRNDQN 663
LP I+ I+K++ YA++ + P L ++A + +++ + L+ N
Sbjct: 702 --LLPPIL----IKKFLSYARQELNPVLNEDASNAVLRYFLELKGSCN 743
>SPCC16A11.17 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 546
Score = 100 bits (249), Expect = 1e-20
Identities = 76/270 (28%), Positives = 116/270 (42%), Gaps = 31/270 (11%)
Query: 145 LSPRTLNSTHLNKLISVEGIVTRTSLVRPKLLRSVHYAQTTGHHHYRDYRDAXXXXXXSV 204
++ R LN ++KLIS++G+V R + V P + ++ GH +
Sbjct: 289 INMRDLNPGDIDKLISIKGLVLRCTPVIPDMKQAFFRCSVCGHCVTVEIDRGRIAEPIKC 348
Query: 205 PTPAIYPEEDQEGNKLVTEYGFCHYMDHQRITVQEMPEKAPPGQLPRSXXXXXXXXXXXK 264
P E N + + + D Q I +QE P+ P GQ P S
Sbjct: 349 PR-----EVCGATNAMQLIHNRSEFADKQVIKLQETPDVVPDGQTPHSVSLCVYDELVDS 403
Query: 265 TKPGDRINIVGVYKSLGAGGLTGGSNNNDKGNGALSGFRTVVIGNTVYPLHARSTG---- 320
+ GDRI + G+++ + N + S F+T V + R G
Sbjct: 404 ARAGDRIEVTGIFRCVPV-------RLNPRMRTVKSLFKTYVDVVHIKKQDKRRLGTDPS 456
Query: 321 -------------VSAVETLSDNDIRNINKLSMHDNIFDTLSQSLAPSIYGHEHIKKAIL 367
+ V +SD ++ I ++S D+I+D LS+SLAPSIY + +KK +L
Sbjct: 457 TLESDIAEDAALQIDEVRKISDEEVEKIQQVSKRDDIYDILSRSLAPSIYEMDDVKKGLL 516
Query: 368 LMLMGGVEKNLPNGS--HLRGDINILMVGD 395
L L GG K+ G+ RGDINILM GD
Sbjct: 517 LQLFGGTNKSFHKGASPRYRGDINILMCGD 546
>Hs22056246 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 112
Score = 66.6 bits (161), Expect = 2e-10
Identities = 28/77 (36%), Positives = 49/77 (63%)
Query: 351 SLAPSIYGHEHIKKAILLMLMGGVEKNLPNGSHLRGDINILMVGDPSTAKSQMLRFVLNT 410
SL P ++G +K A+ ++L GG+++ G+ +RG+ ++L+VGDP T KSQ L++
Sbjct: 30 SLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKI 89
Query: 411 AALAIATTGRGSSGVGL 427
++ TTG GS+ G+
Sbjct: 90 TPRSVLTTGIGSTSAGI 106
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,005,928
Number of Sequences: 60738
Number of extensions: 2054167
Number of successful extensions: 6133
Number of sequences better than 1.0e-05: 51
Number of HSP's better than 0.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5883
Number of HSP's gapped (non-prelim): 125
length of query: 931
length of database: 30,389,216
effective HSP length: 116
effective length of query: 815
effective length of database: 23,343,608
effective search space: 19025040520
effective search space used: 19025040520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)