ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5823 good H KOG2599 Coenzyme transport and metabolism Pyridoxal/pyridoxine/pyridoxamine kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5823 1995234 1994299 -312
(312 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YEL029c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 341 9e-94
YNR027w [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 188 1e-47
7294969 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 175 7e-44
Hs4505701 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 175 9e-44
CE28472 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 156 4e-38
SPCC18.10 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 153 4e-37
SPAC6F6.11c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 153 4e-37
CE11322 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 149 5e-36
At5g37850 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 148 9e-36
>YEL029c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 312
Score = 341 bits (874), Expect = 9e-94
Identities = 171/303 (56%), Positives = 220/303 (72%), Gaps = 6/303 (1%)
Query: 1 MPRVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQ 60
MPR+LA QSHVVHGYVGNKAATFPLQC+GWDVDC NSVQFSNHTGYG+DKVFG+
Sbjct: 1 MPRLLATQSHVVHGYVGNKAATFPLQCLGWDVDCCNSVQFSNHTGYGLDKVFGTITRETD 60
Query: 61 LTQVFEGVM-RLKDDYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGDEGQ 119
L ++ G+ DY ALLSGY+PN+N++ CM +Y + K NP ++WL+DPVMGDEGQ
Sbjct: 61 LKELLSGLFDNFSQDYQALLSGYLPNKNSVRCMGTYYAKFKEANPEMIWLMDPVMGDEGQ 120
Query: 120 LYVDEDVIPEYQDIIHS--GLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIHQFVPVI 177
LYV EDVIPEY+ + S LVDIITPNQFE+E+LYG I L A++++HQ +PVI
Sbjct: 121 LYVSEDVIPEYRKLALSPKQLVDIITPNQFELEILYGGEIKTKEHLKKALKKLHQTIPVI 180
Query: 178 VITSCSASLFDDPTHIYSVSSLRGSPQPYVYRVSVIESYFTGVGDMFSAMLLHQLYYMFE 237
++TSC +FDD IY V+S+ G P VYRV I+SYFTGVGD+FSA+LL ++Y +
Sbjct: 181 IVTSCDCKMFDDKDFIYCVASMEGK-TPIVYRVPFIDSYFTGVGDLFSALLLDRVYKILS 239
Query: 238 SKNISL-FHEKTNVVLNVIHRVLEITKR-LSANVKGSIGDPVTMREMELRVIESIDCYEC 295
+ +L F ++ N VLNVI +VL+IT+ S +K +G + M+EMELR+IES D YE
Sbjct: 240 NPTTTLKFEDQVNNVLNVIQKVLKITRSYASGKMKAKMGSALEMKEMELRLIESRDIYET 299
Query: 296 NSI 298
+I
Sbjct: 300 INI 302
>YNR027w [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 317
Score = 188 bits (477), Expect = 1e-47
Identities = 112/290 (38%), Positives = 166/290 (56%), Gaps = 13/290 (4%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQLT 62
+VL+ QSHV+HGYVGNKAATFPLQ GWDVD +N+VQFSNH+GY G K +L
Sbjct: 10 KVLSIQSHVIHGYVGNKAATFPLQYRGWDVDVLNTVQFSNHSGYA--HFTGFKCSTEELV 67
Query: 63 QVFE----GVMRLKDDYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGDEG 118
+ E G +R+K Y+A+LSGY+PN L +A ++ + N+ W+LDPV+GD G
Sbjct: 68 DIVEKGLIGSLRIK--YDAVLSGYLPNVQALQKVAGIVGQLCEGSENVKWILDPVLGDNG 125
Query: 119 QLYVDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIHQFVP--- 175
+LYVD + + YQDI+ + + + TPNQFEMELL G I + D A + H+ P
Sbjct: 126 RLYVDRECVAVYQDILQNFKIFLATPNQFEMELLVGMSIRTLDDAKQAFKLFHKKYPRVS 185
Query: 176 VIVITSCSASLF-DDPTHIYSVSSLRGSPQPYVYRVSVIESYFTGVGDMFSAMLLHQLYY 234
IV+TS S F + T++ + S + + Y + I + F+G GD+ SAML L
Sbjct: 186 RIVVTSLELSEFLSNDTYVVAGFDCSASEEIFFYEIPKINAKFSGSGDLISAMLTDSLLG 245
Query: 235 MFESKNISLFHEKTNVVLNVIHRVLEITKRLSANVKGSIGDPVTMREMEL 284
+SL VL ++ +L+ T L+ +G + +++++L
Sbjct: 246 DRRCTQLSL-SASLGQVLWLVTSILQKTYDLNIAERGPQDSTIDIKDLKL 294
>7294969 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 494
Score = 175 bits (444), Expect = 7e-44
Identities = 115/292 (39%), Positives = 174/292 (59%), Gaps = 20/292 (6%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQLT 62
RVL+ QSHVVHGYVGNK AT+PLQ +G+DVD +NSVQFSNHTGY K G ++ +L
Sbjct: 11 RVLSIQSHVVHGYVGNKVATYPLQLLGFDVDPLNSVQFSNHTGYKTFK--GPVSNEKELA 68
Query: 63 QVFEGV--MRLKDDYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGDEGQL 120
+FEG+ L Y+ LL+GY+ N L + K++++ NP L+++ DPVMGD GQL
Sbjct: 69 TIFEGLEENELLPLYSHLLTGYIGNPLFLRQVGHILKKLRQANPGLVYVCDPVMGDNGQL 128
Query: 121 YVDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIHQ-FVPVIVI 179
YV ++++P Y+D I L DIITPNQFE+ELL K + + + ++ A++ HQ + +VI
Sbjct: 129 YVPKELLPVYRDEI-IPLADIITPNQFEVELLTEKEVRSEAAVWEAMEWFHQRGIKTVVI 187
Query: 180 TSCSASLFDDPTHIYSVSSLRGSPQPY--VYRVSVIESYFTGVGDMFSAMLLHQLYYMFE 237
S+S P + + S + P+ + + + FTG GD+F+++ L +
Sbjct: 188 ---SSSDLGQPGVLRAFLSQQNGPRLAIDIPKQGGKDLVFTGTGDLFASLF---LAHSHG 241
Query: 238 SKNISLFHEKTNVVLNVIHRVLEITKRLSANVKGSIGDPVTMREMELRVIES 289
SK+I+ EKT I + + KR A++ PV E EL++++S
Sbjct: 242 SKDIANVFEKT------IASLQAVIKRTVASLPNGGNGPVKAAERELKLVQS 287
>Hs4505701 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 312
Score = 175 bits (443), Expect = 9e-44
Identities = 112/300 (37%), Positives = 178/300 (59%), Gaps = 22/300 (7%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQLT 62
RVL+ QSHV+ GYVGN+AATFPLQ +G+++D VNSVQFSNHTGY K G ++ +L
Sbjct: 6 RVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWK--GQVLNSDELQ 63
Query: 63 QVFEGV-MRLKDDYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGD----E 117
+++EG+ + + Y+ +L+GY +++ LA + +E+K+ NP L+++ DPV+GD E
Sbjct: 64 ELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGE 123
Query: 118 GQLYVDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIHQFVP-V 176
G +YV ED++P Y++ + L DIITPNQFE ELL G+ I + + + +H P
Sbjct: 124 GSMYVPEDLLPVYKEKV-VPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDT 182
Query: 177 IVITSCSASLFDDPTHIYSVSSLR-----GSPQPYVYRVSV--IESYFTGVGDMFSAMLL 229
+VITS ++ + S R GS R+ + +++ F G GD+F+AMLL
Sbjct: 183 VVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLL 242
Query: 230 HQLYYMFESKNISLFHEKTNVVLNVIHRVLEITKRLSANVKGSIGDPVTMREMELRVIES 289
+ N+ + EKT ++ +H VL+ T + + G P M ++ELR+++S
Sbjct: 243 AWTHK--HPNNLKVACEKT---VSTLHHVLQRTIQCAKAQAGEGVRPSPM-QLELRMVQS 296
>CE28472 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 338
Score = 156 bits (394), Expect = 4e-38
Identities = 92/232 (39%), Positives = 143/232 (60%), Gaps = 13/232 (5%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQLT 62
RVL+ QSHVVHGY GNK + FPLQ G++VD +NSVQFSNH GY + V G K +L
Sbjct: 44 RVLSIQSHVVHGYAGNKCSVFPLQLHGFEVDFINSVQFSNHAGY--EHVKGQKLTEKELE 101
Query: 63 QVFEGV-MRLKDDYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGDEGQLY 121
+++EG+ + ++Y +L+GY N L +A K++K+ N N ++ DPVMGD G+ Y
Sbjct: 102 ELYEGLTLNNINNYTHVLTGYCGNVTFLQKIADVVKDLKKKNGNTTFVCDPVMGDNGRYY 161
Query: 122 VDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIH-QFVPVIVIT 180
++++P Y+D+I L D++TPN FE+ L G PI D A+ E+H + V +V+T
Sbjct: 162 TPKELMPVYRDLI-IPLADVLTPNAFELGELTGSPIETEEDCLRAVNELHAKGVKTVVVT 220
Query: 181 S-CSASLFDDPTHIYSVSSLRGSPQPYVYRVSV--IESYFTGVGDMFSAMLL 229
S + + ++ Y +S++GS +VYR + + F G GD F+++L+
Sbjct: 221 SGVTGAQTNESLRCY--ASVKGS---HVYRFTFPRLVGQFVGTGDTFTSLLV 267
>SPCC18.10 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 340
Score = 153 bits (386), Expect = 4e-37
Identities = 104/309 (33%), Positives = 160/309 (51%), Gaps = 28/309 (9%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQLT 62
RVL+ QS V HGYVGN++ATFPLQ W+VD V +V FSNH GYG + GS ++
Sbjct: 13 RVLSIQSSVSHGYVGNRSATFPLQLHEWEVDVVPTVHFSNHLGYGATR--GSACIPEEVH 70
Query: 63 QVFEGVMRLKDD---YNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGDEGQ 119
+ + L+D+ Y+A+L+G++PN + + + K+ +P +LWLLDPVMGD+G+
Sbjct: 71 DLLNAL--LQDNGIVYDAILTGFVPNHDIIQVIFDCVLAYKKDHPKVLWLLDPVMGDQGK 128
Query: 120 LYVDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIHQFVPV--I 177
+YVD +VI Y+ +I ITPN FE+E+L I D +++I+Q +
Sbjct: 129 MYVDTNVISTYKAMIPHAFA--ITPNAFEVEILTDIVIHTQMDAKRGLEKIYQLYGIQNA 186
Query: 178 VITSCSASLFDDPTHIYSVSSLRGSPQPYVYRVSVIESYFTGVGDMFSAMLL-------- 229
+ITS S G PQ ++Y+ + FTG GD+FS +LL
Sbjct: 187 IITSFEVEESPGTLFCMGYSCEHGKPQLFLYQFPSLSGVFTGTGDLFSGLLLAKYREELD 246
Query: 230 ----HQLYYMFESKNISLFHEKTNVVLNVIHRVLEITKRLSANV-----KGSIGDPVTMR 280
Q ++K ++ VL+ +H VL TK + + K + + +
Sbjct: 247 KRKHQQSDETKQTKRPTVLACAVGQVLSCMHTVLVNTKTYADEILLEDPKIASDEFLLSN 306
Query: 281 EMELRVIES 289
ELR+I+S
Sbjct: 307 ARELRLIQS 315
>SPAC6F6.11c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 309
Score = 153 bits (386), Expect = 4e-37
Identities = 87/229 (37%), Positives = 131/229 (56%), Gaps = 9/229 (3%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQLT 62
R+LA QS V HGYVGN+AATFPLQ +GWDVD + +V+ SNH GY + K G A Q+
Sbjct: 6 RILAIQSSVCHGYVGNRAATFPLQLLGWDVDAIPTVELSNHAGYPIVK--GRTLSAEQIL 63
Query: 63 QVFEGVMRLK-DDYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGDEGQLY 121
+++GV Y LL+GY ++ + + +K N W+ DPV+GD G+LY
Sbjct: 64 DLYKGVSAANPSGYECLLTGYARGIGSVKAIMEIVRSVKSKNKKAFWVFDPVLGDNGRLY 123
Query: 122 VDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIHQ--FVPVIVI 179
V+E +IP Y++++ D+ITPN FE E+L G I +I + ++ + Q VP +VI
Sbjct: 124 VEESIIPLYREML--PFADLITPNGFEAEILSGMRINSIDTAFKCVECLQQKYKVPRVVI 181
Query: 180 TSCSASLFDDPTHIYSVSSLRGSPQPYVYRVSVIESYFTGVGDMFSAML 228
+S + +Y + S S +V + VI F G GD+F+A++
Sbjct: 182 SSFVVE-ENGVEKLYCIGSSIYSKSFFVL-IPVIPGIFRGTGDLFTALM 228
>CE11322 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 348
Score = 149 bits (376), Expect = 5e-36
Identities = 91/240 (37%), Positives = 142/240 (58%), Gaps = 19/240 (7%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTG--------YGMDKVFGS 54
RVL+ QSHVVHGY GNK + FPLQ G++VD +NSVQFSNH G + V G
Sbjct: 44 RVLSIQSHVVHGYAGNKCSVFPLQLHGFEVDFINSVQFSNHAGNIEYLTLPTRYEHVKGQ 103
Query: 55 KADAHQLTQVFEGV-MRLKDDYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPV 113
K +L +++EG+ + ++Y +L+GY N L +A K++K+ N N ++ DPV
Sbjct: 104 KLTEKELEELYEGLTLNNINNYTHVLTGYCGNVTFLQKIADVVKDLKKKNGNTTFVCDPV 163
Query: 114 MGDEGQLYVDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIH-Q 172
MGD G+ Y ++++P Y+D+I L D++TPN FE+ L G PI D A+ E+H +
Sbjct: 164 MGDNGRYYTPKELMPVYRDLI-IPLADVLTPNAFELGELTGSPIETEEDCLRAVNELHAK 222
Query: 173 FVPVIVITS-CSASLFDDPTHIYSVSSLRGSPQPYVYRVSV--IESYFTGVGDMFSAMLL 229
V +V+TS + + ++ Y +S++GS +VYR + + F G GD F+++L+
Sbjct: 223 GVKTVVVTSGVTGAQTNESLRCY--ASVKGS---HVYRFTFPRLVGQFVGTGDTFTSLLV 277
>At5g37850 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 309
Score = 148 bits (374), Expect = 9e-36
Identities = 107/298 (35%), Positives = 162/298 (53%), Gaps = 33/298 (11%)
Query: 3 RVLACQSHVVHGYVGNKAATFPLQCVGWDVDCVNSVQFSNHTGYGMDKVFGSKADAHQLT 62
RVL+ QSH V GYVGNK+A FPLQ +G+DVD +NSVQFSNHTGY K G + QL
Sbjct: 17 RVLSIQSHTVQGYVGNKSAVFPLQLLGYDVDPINSVQFSNHTGYPTFK--GQVLNGQQLC 74
Query: 63 QVFEGVMRLKD--DYNALLSGYMPNRNTLACMARFYKEIKRHNPNLLWLLDPVMGDEGQL 120
+ EG + D Y +L+GY+ + + L + +++ NPNL ++ DPVMGDEG+L
Sbjct: 75 DLIEG-LEANDLLFYTHVLTGYIGSVSFLDTILEVINKLRSVNPNLTYVCDPVMGDEGKL 133
Query: 121 YVDEDVIPEYQDIIHSGLVDIITPNQFEMELLYGKPIVNISDLYSAIQEIHQFVP-VIVI 179
YV E+++ Y++ + L ++TPNQFE E L G I + D A +H P +VI
Sbjct: 134 YVPEELVHVYREKV-VPLASMLTPNQFEAEKLTGLRINSEEDGREACAILHAAGPSKVVI 192
Query: 180 TSCSASLFDDPTHIYSVSSLRGS--------PQPYVYRVSVIESYFTGVGDMFSAMLLHQ 231
TS + I + L GS P+ + + I +YFTG GD+ +A+LL
Sbjct: 193 TSIT---------IGGILLLIGSHQKEKGLKPEQFKILIHKIPAYFTGTGDLMTALLLG- 242
Query: 232 LYYMFESKNISLFHEKTNVVLNVIHRVLEITKRLSANVKGSIGDPVTMREMELRVIES 289
+ +K + + ++ + +L +R + K + DP T +E+R+I+S
Sbjct: 243 ----WSNKYPDNLDKAAELAVSTLQALL---RRTLDDYKRAGYDP-TSSSLEIRLIQS 292
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.139 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,556,871
Number of Sequences: 60738
Number of extensions: 843514
Number of successful extensions: 1918
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1881
Number of HSP's gapped (non-prelim): 9
length of query: 312
length of database: 30,389,216
effective HSP length: 106
effective length of query: 206
effective length of database: 23,950,988
effective search space: 4933903528
effective search space used: 4933903528
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)