ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5867 check: MH O KOG0941 Posttranslational modification, protein turnover, chaperones E3 ubiquitin protein ligase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5867 2011000 2013417 806
(806 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR036c [O] KOG0941 E3 ubiquitin protein ligase 605 e-173
SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase 336 1e-91
Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase 259 1e-68
Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase 256 1e-67
Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase 256 1e-67
Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase 256 1e-67
7292061 [O] KOG0941 E3 ubiquitin protein ligase 243 8e-64
7294742 [O] KOG0941 E3 ubiquitin protein ligase 233 1e-60
SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 205 3e-52
ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase 202 2e-51
At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 194 5e-49
CE29116 [O] KOG0941 E3 ubiquitin protein ligase 191 3e-48
At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 191 3e-48
SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 188 2e-47
YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 187 4e-47
HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 186 2e-46
Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 186 2e-46
Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase 185 3e-46
Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 184 5e-46
Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 182 2e-45
7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 176 1e-43
SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative up... 176 1e-43
Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 169 1e-41
Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 169 2e-41
7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 168 3e-41
Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 168 3e-41
CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 168 3e-41
7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 167 5e-41
SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 165 2e-40
Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 165 3e-40
Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 165 3e-40
CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 164 5e-40
7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 164 7e-40
YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 162 1e-39
Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase 162 2e-39
ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 161 3e-39
At3g17205 [O] KOG0942 E3 ubiquitin protein ligase 160 6e-39
HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 160 9e-39
Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 160 9e-39
7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 157 8e-38
SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase 156 1e-37
7291760 [O] KOG0942 E3 ubiquitin protein ligase 156 1e-37
CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 154 5e-37
Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 152 2e-36
Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 147 5e-35
Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase 147 6e-35
Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase 145 3e-34
CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 141 5e-33
At3g53090 [O] KOG4427 E3 ubiquitin protein ligase 139 1e-32
Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase 135 3e-31
7295004 [O] KOG4427 E3 ubiquitin protein ligase 132 3e-30
Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 131 4e-30
7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 130 6e-30
Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 128 4e-29
CE19147 [O] KOG4427 E3 ubiquitin protein ligase 127 7e-29
Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase 116 1e-25
YGL141w [O] KOG0942 E3 ubiquitin protein ligase 115 3e-25
At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 110 1e-23
Hs4557026 [S] KOG1426 FOG: RCC1 domain 108 3e-23
At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase 107 9e-23
CE15744 [O] KOG0942 E3 ubiquitin protein ligase 106 1e-22
CE17508 [R] KOG4276 Predicted hormone receptor interactor 92 2e-18
SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase 89 2e-17
At4g38600 [O] KOG0170 E3 ubiquitin protein ligase 82 3e-15
Hs4758520 [S] KOG1426 FOG: RCC1 domain 82 4e-15
7297647 [R] KOG4276 Predicted hormone receptor interactor 79 4e-14
Hs15300020 [R] KOG4276 Predicted hormone receptor interactor 77 1e-13
YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase 74 7e-13
Hs7661612 [O] KOG0941 E3 ubiquitin protein ligase 72 3e-12
CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplas... 70 2e-11
Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperp... 66 2e-10
Hs13375805 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 62 3e-09
Hs17460052 [O] KOG0941 E3 ubiquitin protein ligase 56 2e-07
>YJR036c [O] KOG0941 E3 ubiquitin protein ligase
Length = 892
Score = 605 bits (1560), Expect = e-173
Identities = 344/835 (41%), Positives = 496/835 (59%), Gaps = 72/835 (8%)
Query: 28 EDPPKFRETRCRCCGTLLRHPIDAVKFKCTICEVTVVLRQTANSRDTEGK--ILPDLEQL 85
ED C CCG LR P KF+C+ C+VTV++++ + + E I LE L
Sbjct: 74 EDKSCLISLNCLCCGVPLRFPASITKFRCSACQVTVIVKEPEINSNLESSTHISCTLEGL 133
Query: 86 SNIVGQCLESYKKDQTGDETPAKELNSYFIPVEKYIVQKFGTAEALNQLFKPTVKD---- 141
+V +C + ++ + + F PV Y++ +F LN+ F V D
Sbjct: 134 QMVVRRCHDDLQRLKKTGILDKERKGLIFQPVITYLLDRFHDVSILNRSF--LVHDGGKN 191
Query: 142 -QIINYEKAVTFYNLIGSLPTKRPIYLILRVFNEVLKRPKILMDKWEH-----YLFIFFI 195
+++NYE FY+++ +LPT++P Y +L N++LKR I ++K E+ Y ++ I
Sbjct: 192 IKMLNYEVLQRFYSILSNLPTRKPYYSMLCCCNDLLKR--ITINKGENLQILQYRWLLII 249
Query: 196 LEVPSLRQCI---NNSTTISRTPKIKTLSYEILKRCIGYLGSMNSKVSVKYKNHLVRLHP 252
L +P++R C+ S + T +I+ +SYE+ KRCIGYL ++++K S + L R
Sbjct: 250 LNIPTIRTCLIRDRKSKNVFETQQIRAVSYELAKRCIGYLSNLSTKTSQQLIQSLRRTPT 309
Query: 253 LKFQKQWEILNLYLSYQFQKI------------GPGPPHSPRG------LSGTLLTESSP 294
F Q EILNLY+++QF ++ P R +G + P
Sbjct: 310 DNFSYQVEILNLYINFQFSRLLSNELSNRTAKNNVKPEDEMRSRLRRHHTTGHEFLSTRP 369
Query: 295 VD-ETKDGTVSYLFHPGRQKIPLESRFRIEKYGLDWHIRTVCQLMNIYFQAHCEQP---K 350
+ ++ D S HP K+ +F+ +Y DWHI + +L IY+ A+ +
Sbjct: 370 ISAQSNDKQGSGFTHPVNNKM----KFKFFQYEEDWHIHSAAKLTFIYYVANTRRNGRGA 425
Query: 351 CDISVFYNMIIDFIDYKRDFMMWH------KMNR--EQWRTLDDLSMTQLHETHYTALCQ 402
I FYN+ +DFIDYK+DF W KMN+ E+W S T+ + C+
Sbjct: 426 LSIQSFYNITLDFIDYKQDFDHWRGVAQKTKMNQLIEEWGN----STTK----KCFSFCK 477
Query: 403 YPFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTS 462
YPF++SLG+KI+IME+E ++MEH AEQAFL +LD K DV+F+IKVRR ++ DSL
Sbjct: 478 YPFILSLGIKISIMEYEIRRIMEHEAEQAFLISLDKGKSVDVYFKIKVRRDVISHDSLRC 537
Query: 463 IQRHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAY 522
I+ H DL KSLR+EF NEPGIDAGGL+KEWF LLT+ LF+P +GLF Y++ES SWFA
Sbjct: 538 IKEHQGDLLKSLRIEFVNEPGIDAGGLRKEWFFLLTKSLFNPMNGLFIYIKESSRSWFAI 597
Query: 523 GNTGL-KLHGENNN-ELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEEL 580
K G+N+ ELYYLFGVV+GLAI+NSTILDL F +A+YKKLC+E ++FEDY EL
Sbjct: 598 DPPNFDKSKGKNSQLELYYLFGVVMGLAIFNSTILDLQFPKALYKKLCSEPLSFEDYSEL 657
Query: 581 YPETARNLKKMLSYSELDFSDIFGLSFETTYYD--------VASGINVTKPLCDGGESIP 632
+PET+RNL KML+Y+E +F D+F L+FETTY + +S VT LC+ G ++P
Sbjct: 658 FPETSRNLIKMLNYTEDNFEDVFSLTFETTYRNNNWILNDSKSSKEYVTVELCENGRNVP 717
Query: 633 VTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIE 692
+T NK EFV +WV FY+ + + ++ F SGF RV + + +F S E+ERL+CG E
Sbjct: 718 ITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSIKLFNSEELERLVCGDEE 777
Query: 693 Q-DMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLA 751
Q DF+ LR+VTKY GGF + + V W WEI+ + Q++ L FVT SDR+P TG++
Sbjct: 778 QTKFDFKSLRSVTKYVGGFSDDSRAVCWFWEIIESWDYPLQKKLLQFVTASDRIPATGIS 837
Query: 752 TLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYGFK 806
T+PFK++ S D LP AHTCFNE+CL+ Y S+ L L+L+ A+ EGYGF+
Sbjct: 838 TIPFKISLLGSHDSDDLPLAHTCFNEICLWNYSSKKKLELKLLWAINESEGYGFR 892
>SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase
Length = 807
Score = 336 bits (861), Expect = 1e-91
Identities = 239/810 (29%), Positives = 387/810 (47%), Gaps = 126/810 (15%)
Query: 38 CRCCGTLLRHPIDAVKFKCTIC----EVTVVLR--QTANSRDTEGKILPDLEQLSNIVGQ 91
C CC ++LR+P A+ F+C++C +V L Q T+G +E + Q
Sbjct: 83 CICCNSVLRYPAQAMCFRCSLCMTVNDVYFCLSGSQIKTKASTDGSQFISVEHFVETIHQ 142
Query: 92 CLESYK--KDQTGDETPAKELNSYFIPVEKYIVQKFGTAEALNQLFKP----TVKDQIIN 145
+ + K +TG+ + + + +P+ + I FG+ LN+LF +++ +N
Sbjct: 143 TRSALQLAKQRTGN---VQAIVAAGLPLRELISLVFGSPPILNKLFSVKNGCSIQSSGLN 199
Query: 146 YEKAVTFYNLIGSLPTKRPIYLILRVFNEVLKRPKILMDKWEHYLFIFFILEVPSLRQCI 205
Y+ Y+ I +L L LR +L+RP + Y ++ +LE P L
Sbjct: 200 YKLIYQLYHDITNLDILITNEL-LRAIESLLRRPMLYCHDPADYQYLLILLENPLLN--- 255
Query: 206 NNSTTISRTPKIKTLSYEILKRCIGYLGSMNSKVSVKYKNHLVRL---HPLKFQKQWEIL 262
S++ I S ILKR +G L ++N K + + + +P F+++ +++
Sbjct: 256 ------SKSKNIVNKSSSILKRILGVLSNLNEKTHHFFISCFKKQPYNNPKFFRRKVDLI 309
Query: 263 NLYLSYQFQKIGPGPPHSPRGLSGTLLTESSPVDETKDGTVSYLFHPGRQKIPLESRFRI 322
N ++ G L E+ ++ K
Sbjct: 310 NKFI-------------------GQRLMETYSRNKRK----------------------- 327
Query: 323 EKYGLDWHIRTVCQLMNIYFQAHCEQPKCDISVFYNMIIDFIDYKRDFMMWHKMNREQWR 382
Y DW I++ M + + A+ + D S FY ++ DFI+ DF +W +
Sbjct: 328 HYYNNDWQIKSAAITMALLYSANSQMRLIDRSSFYCIMADFINLYHDFELWEQ------- 380
Query: 383 TLDDLSMTQLHETHYTALCQYPFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLY 442
+ + CQYPFL+S+G KI+I++ + + ME A +AF ++ S+
Sbjct: 381 -----------KINCFCFCQYPFLLSMGAKISILQLDARRKMEIKAREAFFSSILSKMNV 429
Query: 443 DVHFRIKVRRSHVTQDSLTSIQRHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELF 502
+ + I+VRR + +DSL I D +K+L+VEF E GIDAGGLK+EW LLLTR++F
Sbjct: 430 EPYLMIRVRRDRLLEDSLRQINDRNKDFRKALKVEFLGEEGIDAGGLKREWLLLLTRKVF 489
Query: 503 HPNHGLFQYVEE-SRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFAR 561
P GLF EE S WF Y H + Y++ G+++G+AI+NS LD+ R
Sbjct: 490 SPEFGLFVNCEESSNYLWFNYS------HRSKEIDYYHMSGILMGIAIHNSINLDVQMPR 543
Query: 562 AMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
A YKKL ++F D ++ P R LK++L + E D + +GL+F T G T
Sbjct: 544 AFYKKLLQLPLSFNDLDDFQPSLYRGLKELLLF-EGDVKNTYGLNF-TINLKAVEGFR-T 600
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSC 681
L +GG + V +EN+ E+V R+V++ +N V FSAF GF +V G G A +F+
Sbjct: 601 VELKEGGSELSVDNENRKEYVLRYVDYLLNTTVKKQFSAFFDGFMKVCG-GNAISLFQDN 659
Query: 682 EVERLICGSIEQDMDFEQLRAVTKYQ-------------------------GGFHNQTPV 716
E+ +LI GS E+ +D+E L+ V Y F ++ +
Sbjct: 660 EISKLIRGS-EEVIDWELLKNVCVYDFYDQNAISNSISESEPSMTASKYLCHSFVSKRKI 718
Query: 717 VEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTRTTSGSHDQLPTAHTCFN 776
+ W W+++ S + Q+ FL FVTGSDR+P TG +++ DQLP +HTCFN
Sbjct: 719 ILWFWDLISHYSLKMQKLFLIFVTGSDRIPATGAHNFQLRIS-VLGPDSDQLPISHTCFN 777
Query: 777 ELCLYEYESRDTLLLRLVTALEMYEGYGFK 806
LC++EY SR+ L +L TAL G+ +
Sbjct: 778 HLCIWEYSSREKLKKKLDTALLETNGFNIR 807
>Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1050
Score = 259 bits (661), Expect = 1e-68
Identities = 159/484 (32%), Positives = 262/484 (53%), Gaps = 32/484 (6%)
Query: 330 HIRTVCQLMNIYFQAHCEQPKCDISVFY-NMIIDFIDYKRDFMMW--HKMNREQWRTLDD 386
+I +L+ ++ + + + FY I + +D + D++MW H+ + ++
Sbjct: 586 YITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQ 645
Query: 387 LSMTQLHETHYTALCQYPFLMSLGVKIAIMEFETGKMME-----HNAEQAF-LKALDSRK 440
++T LC YPF+ K +++ + M+ N + F L L+
Sbjct: 646 DTVT---------LCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLL 696
Query: 441 LYDVHFRIKVRRSHVTQDSLTSIQRHPH-DLKKSLRVEFSNEPGIDAGGLKKEWFLLLTR 499
+ VRR+++ D+L + H DLKK L+V F E +DAGG+ KE+FLLL +
Sbjct: 697 ARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLK 756
Query: 500 ELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHF 559
EL +P +G+F Y ++S L WF+ +T H ++L G+ GLAIYNST++DLHF
Sbjct: 757 ELLNPIYGMFTYYQDSNLLWFS--DTCFVEHN-----WFHLIGITCGLAIYNSTVVDLHF 809
Query: 560 ARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGIN 619
A+YKKL N + ED +EL P R+L+++L Y D + F L+F T + G+
Sbjct: 810 PLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNF--TICRESYGVI 867
Query: 620 VTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFK 679
K L GG+++ V +N+ EFV+ +VN+ V ++AF SGF +V G G +F+
Sbjct: 868 EQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCG-GKVLELFQ 926
Query: 680 SCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFV 739
E+ ++ G+ + ++E+L Y+G + P V+ WE + E++++FL F+
Sbjct: 927 PSELRAMMVGN--SNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFL 984
Query: 740 TGSDRVPVTGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEM 799
TGSDR+P+ G+A+L + T SG + LP AHTC+N L L +Y S++ L RL AL+
Sbjct: 985 TGSDRIPIYGMASLQIVIQSTASG-EEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDN 1043
Query: 800 YEGY 803
YEG+
Sbjct: 1044 YEGF 1047
>Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase
Length = 875
Score = 256 bits (653), Expect = 1e-67
Identities = 144/405 (35%), Positives = 233/405 (56%), Gaps = 16/405 (3%)
Query: 404 PFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSI 463
PF+++ K + ++ M L +L + + + R+KVRR H+ D+L +
Sbjct: 481 PFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRL 540
Query: 464 Q----RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSW 519
+ +P DLKK L VEF E G+D GG+ KE+F L+ E+F+P+ G+F Y E ++L W
Sbjct: 541 EMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFW 600
Query: 520 FAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEE 579
F + + G+ + L G+VLGLAIYN+ ILD+HF +Y+KL ++ TF D +
Sbjct: 601 F--NPSSFETEGQ-----FTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLGD 653
Query: 580 LYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKT 639
+P ++LK +L Y E + D ++F+ + D+ G + L + G+ IP+T+EN+
Sbjct: 654 SHPVLYQSLKDLLEY-EGNVEDDMMITFQISQTDL-FGNPMMYDLKENGDKIPITNENRK 711
Query: 640 EFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQ 699
EFV + ++ +N+ V F AF+ GF V + +F+ E+E LICGS +++DF+
Sbjct: 712 EFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGS--RNLDFQA 769
Query: 700 LRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTR 759
L T+Y GG+ + ++ WEI+ + EQ+R FL F TG+DR PV GL L + +
Sbjct: 770 LEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAK 829
Query: 760 TTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
+ ++LPT+HTCFN L L EY S++ L RL+ A+ +G+G
Sbjct: 830 NGPDT-ERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFG 873
>Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase
Length = 872
Score = 256 bits (653), Expect = 1e-67
Identities = 144/405 (35%), Positives = 233/405 (56%), Gaps = 16/405 (3%)
Query: 404 PFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSI 463
PF+++ K + ++ M L +L + + + R+KVRR H+ D+L +
Sbjct: 478 PFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRL 537
Query: 464 Q----RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSW 519
+ +P DLKK L VEF E G+D GG+ KE+F L+ E+F+P+ G+F Y E ++L W
Sbjct: 538 EMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFW 597
Query: 520 FAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEE 579
F + + G+ + L G+VLGLAIYN+ ILD+HF +Y+KL ++ TF D +
Sbjct: 598 F--NPSSFETEGQ-----FTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLGD 650
Query: 580 LYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKT 639
+P ++LK +L Y E + D ++F+ + D+ G + L + G+ IP+T+EN+
Sbjct: 651 SHPVLYQSLKDLLEY-EGNVEDDMMITFQISQTDL-FGNPMMYDLKENGDKIPITNENRK 708
Query: 640 EFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQ 699
EFV + ++ +N+ V F AF+ GF V + +F+ E+E LICGS +++DF+
Sbjct: 709 EFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGS--RNLDFQA 766
Query: 700 LRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTR 759
L T+Y GG+ + ++ WEI+ + EQ+R FL F TG+DR PV GL L + +
Sbjct: 767 LEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAK 826
Query: 760 TTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
+ ++LPT+HTCFN L L EY S++ L RL+ A+ +G+G
Sbjct: 827 NGPDT-ERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFG 870
>Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase
Length = 852
Score = 256 bits (653), Expect = 1e-67
Identities = 144/405 (35%), Positives = 233/405 (56%), Gaps = 16/405 (3%)
Query: 404 PFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSI 463
PF+++ K + ++ M L +L + + + R+KVRR H+ D+L +
Sbjct: 458 PFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRL 517
Query: 464 Q----RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSW 519
+ +P DLKK L VEF E G+D GG+ KE+F L+ E+F+P+ G+F Y E ++L W
Sbjct: 518 EMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFW 577
Query: 520 FAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEE 579
F + + G+ + L G+VLGLAIYN+ ILD+HF +Y+KL ++ TF D +
Sbjct: 578 F--NPSSFETEGQ-----FTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLGD 630
Query: 580 LYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKT 639
+P ++LK +L Y E + D ++F+ + D+ G + L + G+ IP+T+EN+
Sbjct: 631 SHPVLYQSLKDLLEY-EGNVEDDMMITFQISQTDL-FGNPMMYDLKENGDKIPITNENRK 688
Query: 640 EFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQ 699
EFV + ++ +N+ V F AF+ GF V + +F+ E+E LICGS +++DF+
Sbjct: 689 EFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGS--RNLDFQA 746
Query: 700 LRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTR 759
L T+Y GG+ + ++ WEI+ + EQ+R FL F TG+DR PV GL L + +
Sbjct: 747 LEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAK 806
Query: 760 TTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
+ ++LPT+HTCFN L L EY S++ L RL+ A+ +G+G
Sbjct: 807 NGPDT-ERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFG 850
>7292061 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1057
Score = 243 bits (620), Expect = 8e-64
Identities = 152/478 (31%), Positives = 258/478 (53%), Gaps = 41/478 (8%)
Query: 331 IRTVCQLMNIYFQAHCEQPKCDISVFY-NMIIDFIDYKRDFMMWHKMNREQWRTLDDLSM 389
++T+CQ+ N + H + + +FY + D+ D +++++ W + T D +
Sbjct: 613 MKTLCQINN---ERH---DRLNYQIFYWPDLSDYADVQQEYVKWIMAD-----TARDFN- 660
Query: 390 TQLHETHYTALCQYPFLMSLGVKIAIMEFETGKMMEH---NAEQAFLKALDSRKLYDVHF 446
+C Y F+ K A+++ + M NA +
Sbjct: 661 ----------ICNYSFIFDQSAKTALLQADQALQMHSAMANAATMAFSFFNYGMPISQFI 710
Query: 447 RIKVRRSHVTQDSLTSIQRHPH-DLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPN 505
+ V R ++ QDSL +Q + DLKK L+++F E DAGG++KE+F+LL ++L P
Sbjct: 711 VLNVTRENLVQDSLRELQHYSQSDLKKPLKIKFHGEEAEDAGGVRKEFFMLLLKDLLDPK 770
Query: 506 HGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYK 565
+G+F+ E+SRL WFA L EN +Y+L GV+ GLAIYN TI++L F A++K
Sbjct: 771 YGMFKEYEQSRLLWFA----DLTFETEN---MYFLIGVLCGLAIYNFTIINLPFPLALFK 823
Query: 566 KLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLC 625
KL + + D +L P A +++ +L Y DF ++F L+FE + DV G TK L
Sbjct: 824 KLLGKPVDLSDLRQLSPPEANSMQSLLDYQGDDFKEVFDLTFEIS-RDV-FGEAETKCLK 881
Query: 626 DGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVER 685
G I VT EN+ EFV+ +V+F N+ V ++AF GF +V G +F+ E+
Sbjct: 882 PNGNEIAVTLENRQEFVDLYVDFVFNKSVELHYNAFHKGFMKVC-SGRVIHIFQPEELMA 940
Query: 686 LICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRV 745
++ G+ +D D++ L+ +Y+ G+ + ++W WE++ +S +++ FL F+TGSDR+
Sbjct: 941 VVVGN--EDYDWQALQDNCEYREGYTSVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRI 998
Query: 746 PVTGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGY 803
P+ G+ L K+T + LP AHTCFN L L Y++++ L +L+ A++ +G+
Sbjct: 999 PIQGMKAL--KLTIQPTPDERFLPVAHTCFNLLDLPRYKTKERLKYKLLQAIQQTQGF 1054
>7294742 [O] KOG0941 E3 ubiquitin protein ligase
Length = 973
Score = 233 bits (593), Expect = 1e-60
Identities = 148/470 (31%), Positives = 237/470 (49%), Gaps = 30/470 (6%)
Query: 346 CEQPKCDISVFYNMII-DFIDYKRDFMMWHKMNREQWRTLDDLSMTQLHETHYTALCQYP 404
C +P + FYN + + I D++ ++TL S +Y + Y
Sbjct: 521 CRKPLIPLEEFYNEALSENIQMHHDYL--------SYKTLAMESEIGSGHANYFSFMLYA 572
Query: 405 FLMSLGVKIAIMEFETGKMM---EHNAEQAFLKALDSRKLYD---VHFRIKVRRSHVTQD 458
F+++ K+ + +++ M +++ + L + D ++ VRR + D
Sbjct: 573 FILTPSTKVDALYYDSRMRMYSERYSSLHSILNNIGQVGQEDNPRPDLKLTVRRDQLIND 632
Query: 459 SLTSIQR----HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEE 514
+L ++ +P DLKK L VEF E GID GG+ KE+F L+ E+F+P G+F EE
Sbjct: 633 ALIGLEMVAMSNPKDLKKQLVVEFVGEQGIDEGGVSKEFFQLIVEEIFNPAFGMFIQQEE 692
Query: 515 SRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITF 574
+ WF N + L G+++GLAIYN+ L ++F +Y+KL TF
Sbjct: 693 TNNMWF-------NATPFENGAQFTLIGIIIGLAIYNNVTLAVNFPMVVYRKLIGYCGTF 745
Query: 575 EDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVT 634
D + P ++LK ML Y D ++F +F+ +Y DV + V L G+ + V
Sbjct: 746 ADLSDWSPALYKSLKSMLDYQGQDMEEVFEQTFKISYSDVFGDV-VQHELVPNGQDVLVG 804
Query: 635 SENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQD 694
NK FV + +F +N + F+AF+ GF V + +F+ E+E L+CGS ++
Sbjct: 805 QHNKELFVNLYSDFLLNTNIEQQFNAFRKGFEMVTDESPLKLLFRPEEIEMLVCGS--RE 862
Query: 695 MDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLP 754
DF +L T Y+GG+ ++ ++ W I+ + E + + L F TGS RVPV GL L
Sbjct: 863 FDFVELENSTVYEGGYTEKSQYIQDFWSIVHAMPSEDKHKLLEFTTGSARVPVGGLKCLR 922
Query: 755 FKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
+TR S D+LPT+HTCFN L L EY SR+ L RL+ A+ +G+G
Sbjct: 923 LLITRHGPDS-DRLPTSHTCFNVLLLPEYSSREKLEERLMKAINYSKGFG 971
>SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 786
Score = 205 bits (521), Expect = 3e-52
Identities = 135/368 (36%), Positives = 200/368 (53%), Gaps = 28/368 (7%)
Query: 448 IKVRRSHVTQDSLTSIQRHP-HDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNH 506
+KVRR H+ +DS I R+ HDLKK L + F E G+D GGL +E+F LL+ ++F P +
Sbjct: 434 VKVRRDHIFEDSYAEIMRYSAHDLKKRLMIRFDGEDGLDYGGLSREFFFLLSHKMFDPIY 493
Query: 507 GLFQYVEESRLSWFAYGNTGLKL--HGENNNE---LYYLFGVVLGLAIYNSTILDLHFAR 561
LF+Y A N L++ H N E + G V+GLAI++ LD F
Sbjct: 494 CLFEY--------SAVDNYTLQINPHSSINPEHLNYFRFIGRVIGLAIFHRRFLDAFFVV 545
Query: 562 AMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
++YKKL ++++ D E + E R+LK +L E D + I L+F + G T
Sbjct: 546 SLYKKLLRKKVSLADMESIDAEFYRSLKWVL---ENDITGILDLTFSVE--EDHFGEVRT 600
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSC 681
L GE+I VT ENK ++V+ + +++ V F+AF SGF ++ L +F
Sbjct: 601 VELITNGENIEVTEENKKKYVDLVTEWRVSKRVEQQFNAFYSGFVELVSPDLV-NVFDER 659
Query: 682 EVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTG 741
E+E LI G D+D E ++ T+Y+ + PV++W WEI+ +E + + L F TG
Sbjct: 660 ELELLIGGI--SDVDVEDWKSHTEYR-TYIATDPVIKWFWEIIAGWKNEDRSKLLQFATG 716
Query: 742 SDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+ R+PV G L P K T +G+ DQLP AHTCFN L L +Y S+DTL +L A
Sbjct: 717 TSRIPVNGFRDLQGSDGPRKFTIEKAGTPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLA 776
Query: 797 LEMYEGYG 804
+E G+G
Sbjct: 777 VENTVGFG 784
>ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase
Length = 746
Score = 202 bits (513), Expect = 2e-51
Identities = 138/447 (30%), Positives = 243/447 (53%), Gaps = 39/447 (8%)
Query: 364 IDYKRDFMM--WHKMN-REQWRTLDDLSMTQLHETHYTALCQYPFLMSLGVKIAIMEFET 420
+ YK+ +++ +MN RE+++ S T L+ + F++ + +K ++++E
Sbjct: 329 LSYKKFYLVSFCSRMNFREEFKHFRAKSKTPLN---------FQFILPVHIKAELIKYEN 379
Query: 421 GKMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFS 479
M+ + + +F K+L + D + I V R V +DS+ ++ + D +K LR+ F
Sbjct: 380 NDRMKTSLQDSFFKSLFEGHV-DPYLFITVSRETVYRDSIEIFKKINVLDARKQLRITFR 438
Query: 480 NEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYY 539
NE G+D+GG++KE+F LL++E+ E+ RL ++ H E + E Y
Sbjct: 439 NEEGVDSGGIRKEYFQLLSQEI----------KEDERLFEHTENRIWIRPH-EGDGEGYE 487
Query: 540 LFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKM--LSYSEL 597
G ++ +A+YN+ +L++ F +KKL + R T +D E+ A +L+ + LS E+
Sbjct: 488 AIGRIIAIALYNNVVLNIPFPSLFFKKLLDRRPTLDDLREISSGIATSLRNLRRLSRDEV 547
Query: 598 DFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSS 657
D D L F + GI + PL GE I +TSEN F+E++V F+ + +
Sbjct: 548 DSLD---LRFVVEHS--VDGIPRSYPLVKNGEDIKLTSENMRLFIEKYVEFHTDALIKPQ 602
Query: 658 FSAFQSGFTRVIG-DGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPV 716
F + + GF +I D LA+ K E+E+++ GS D + +R+ T Y G F +P+
Sbjct: 603 FESIKRGFYSIIDKDKLAYLDPK--ELEKIMMGS--NTFDIKAIRSTTTYSG-FREDSPI 657
Query: 717 VEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTRTTSGSHDQLPTAHTCFN 776
+ + WEI + +++++ L F+TG+DR+PV+G A+L + R + D+LP++ TCFN
Sbjct: 658 IVYFWEIFEAFNRKKRKKLLQFITGNDRIPVSGPASLKLVIMRNGCDT-DRLPSSQTCFN 716
Query: 777 ELCLYEYESRDTLLLRLVTALEMYEGY 803
L L EY S+D L +L TALE+ G+
Sbjct: 717 TLLLPEYSSKDKLEGKLETALELTAGF 743
>At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3891
Score = 194 bits (493), Expect = 5e-49
Identities = 136/415 (32%), Positives = 219/415 (52%), Gaps = 29/415 (6%)
Query: 408 SLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHF----RIKVRRSHVTQDSLTSI 463
SL K M + ++++ + ++A+ ++ R +D H RI VRR++V +DS +
Sbjct: 3488 SLLEKSLSMMLKAPRLIDFDNKKAYFRSR-IRHQHDQHISGPLRISVRRAYVLEDSYNQL 3546
Query: 464 Q-RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAY 522
+ R P DLK L V+F E GIDAGGL +EW+ LL+R +F LF V +
Sbjct: 3547 RMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDA----TF 3602
Query: 523 GNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYP 582
++ + + G ++ A+++ +LD++F R+ YK + ++T+ D E + P
Sbjct: 3603 QPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDP 3662
Query: 583 ETARNLKKMLSYSELDFSDIFGLSF----ETTYYDVASGINVTK-PLCDGGESIPVTSEN 637
+ +NLK +L E D SDI L+F + + + VT L GG +I VT E
Sbjct: 3663 DYYKNLKWLL---ENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEET 3719
Query: 638 KTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDF 697
K E+V+ + + +AF GF +I L +F E+E LI G E +DF
Sbjct: 3720 KHEYVDLVAGHILTNAIRPQINAFLEGFNELIPRELV-SIFNDKELELLISGLPE--IDF 3776
Query: 698 EQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL---- 753
+ L+A T+Y + +PV+ W WE++ S E +FL FVTG+ +VP+ G L
Sbjct: 3777 DDLKANTEYT-SYTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGIS 3835
Query: 754 -PFKV-TRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTAL-EMYEGYGF 805
P ++ G+ ++LP+AHTCFN+L L EY+S++ L RL+ A+ E EG+GF
Sbjct: 3836 GPQRLQIHKAYGAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEGFGF 3890
>CE29116 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1019
Score = 191 bits (486), Expect = 3e-48
Identities = 125/424 (29%), Positives = 217/424 (50%), Gaps = 19/424 (4%)
Query: 386 DLSMTQLHETHYTALCQYPFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDV- 444
+L+ ++T +PFL++ K ++ E M + + ++++
Sbjct: 606 ELTRQDPNKTELDYWTHFPFLLNGVAKGELIFVEAWLMQTLRRQSSLFNTAHGTIIFELP 665
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H + VRR + D++ + DL+K L+V + E DAGG++KE+F+L+ R++
Sbjct: 666 HLELTVRREFIVSDTMNQMAGLSESDLQKPLKVNIAGEDADDAGGVRKEFFILVMRKILQ 725
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
++G+F EES L WF+ GL + + + L G ++GL+IYN +I+ F A+
Sbjct: 726 SDYGMFSEDEESHLVWFS----GLPSEFCDREQFHQL-GRLVGLSIYNHSIVPFPFPLAL 780
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKP 623
YK L + ED EL P + LK +LSY E D D+FGL+F ++ + G T
Sbjct: 781 YKYLLDTPPDLEDLCELSPSEGKGLKMLLSYEEDDVEDVFGLNFCISFNIL--GETHTTE 838
Query: 624 LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFS----AFQSGFTRVIGDGLAFPMFK 679
L GG PVT+ N+ E+V +V+ + G + + F+ GF+ + F+
Sbjct: 839 LLSGGTEKPVTNANRDEYVRLYVHHRLELGYNGEIAQQALLFRKGFSESL-HSRTLRFFQ 897
Query: 680 SCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFV 739
CE++ +I G+ ++ D+ + R + Y+G + + P ++ W+ L+ +++R+FL F+
Sbjct: 898 PCELKEMIVGN--ENYDWNEFRDILMYRGEYSSSHPTIQAFWKAFFALTDDERRKFLQFL 955
Query: 740 TGSDRVPVTGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEM 799
TGS R+PV+G L + + + LP AHTCFN L L LL RL ++E
Sbjct: 956 TGSTRIPVSGWEELHAAI---QPSAPESLPVAHTCFNLLDLPNIADDVELLRRLRISIEH 1012
Query: 800 YEGY 803
EG+
Sbjct: 1013 TEGF 1016
>At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3658
Score = 191 bits (486), Expect = 3e-48
Identities = 135/415 (32%), Positives = 219/415 (52%), Gaps = 29/415 (6%)
Query: 408 SLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHF----RIKVRRSHVTQDSLTSI 463
SL K M + ++++ + ++A+ ++ R +D H RI VRR++V +DS +
Sbjct: 3255 SLLEKSFSMMLKAPRLIDFDNKKAYFRSR-IRHQHDQHISGPLRISVRRAYVLEDSYNQL 3313
Query: 464 Q-RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAY 522
+ R P DLK L V+F E GIDAGGL +EW+ LL+R +F LF V +
Sbjct: 3314 RMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDA----TF 3369
Query: 523 GNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYP 582
++ + + G ++ A+++ +LD++F R+ YK + ++T+ D E + P
Sbjct: 3370 QPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDP 3429
Query: 583 ETARNLKKMLSYSELDFSDIFGLSF----ETTYYDVASGINVTK-PLCDGGESIPVTSEN 637
+ +NLK +L E D SDI L+F + + + VT L GG +I VT E
Sbjct: 3430 DYYKNLKWLL---ENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEET 3486
Query: 638 KTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDF 697
K E+V+ + + + +AF G +I L +F E+E LI G E +DF
Sbjct: 3487 KHEYVDLVADHILTSAIRPQINAFLEGLNELIPRELV-SIFNDKELELLISGLPE--IDF 3543
Query: 698 EQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL---- 753
+ L+A T+Y + +PV+ W WE++ S E +FL FVTG+ +VP+ G L
Sbjct: 3544 DDLKANTEYT-SYTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGIS 3602
Query: 754 -PFKV-TRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTAL-EMYEGYGF 805
P ++ GS ++LP+AHTCFN+L L EY+S++ + RL+ A+ E EG+GF
Sbjct: 3603 GPQRLQIHKAYGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEGFGF 3657
>SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 767
Score = 188 bits (478), Expect = 2e-47
Identities = 125/364 (34%), Positives = 194/364 (52%), Gaps = 20/364 (5%)
Query: 448 IKVRRSHVTQDSLTSIQRHPH-DLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNH 506
IKVRR+H+ +DS I R DLKK L ++F E G+D GGL +E+F LL+ E+F+P +
Sbjct: 415 IKVRRNHIFEDSYAEIMRQSATDLKKRLMIKFDGEDGLDYGGLSREYFFLLSHEMFNPFY 474
Query: 507 GLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLF-GVVLGLAIYNSTILDLHFARAMYK 565
LF+Y + ++G+ N Y+ F G V+GLAI++ +D F + YK
Sbjct: 475 CLFEYSSVDNYTLQINPHSGINPEHLN----YFKFIGRVIGLAIFHRRFVDAFFVVSFYK 530
Query: 566 KLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLC 625
+ +++T +D E + E R+L +L + D + + L+F D G VT L
Sbjct: 531 MILQKKVTLQDMESMDAEYYRSLVWIL---DNDITGVLDLTFSVE--DNCFGEVVTIDLK 585
Query: 626 DGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVER 685
G +I VT ENK E+V+ + + + + F+AF GF+ +I L +F E+E
Sbjct: 586 PNGRNIEVTEENKREYVDLVTVWRIQKRIEEQFNAFHEGFSELIPQEL-INVFDERELEL 644
Query: 686 LICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRV 745
LI G E DM E + T Y+ + +++W WE++ + S+E++ + L F TG+ R+
Sbjct: 645 LIGGISEIDM--EDWKKHTDYR-SYSENDQIIKWFWELMDEWSNEKKSRLLQFTTGTSRI 701
Query: 746 PVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMY 800
PV G L P K T +G ++LP AHTCFN L L Y S+ L +L A+E
Sbjct: 702 PVNGFKDLQGSDGPRKFTIEKAGEPNKLPKAHTCFNRLDLPPYTSKKDLDHKLSIAVEET 761
Query: 801 EGYG 804
G+G
Sbjct: 762 IGFG 765
>YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 809
Score = 187 bits (476), Expect = 4e-47
Identities = 123/368 (33%), Positives = 190/368 (51%), Gaps = 28/368 (7%)
Query: 448 IKVRRSHVTQDSLTSIQRH-PHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNH 506
IKVRR ++ +D+ I R P DLKK L ++F E G+D GG+ +E+F LL+ E+F+P +
Sbjct: 457 IKVRRKNIFEDAYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 516
Query: 507 GLFQYVEESRLSWFAYGNTGLKLH---GENNNELYY--LFGVVLGLAIYNSTILDLHFAR 561
LF+Y AY N ++++ G N L Y G V+GL +++ LD F
Sbjct: 517 CLFEY--------SAYDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVG 568
Query: 562 AMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
A+YK + +++ +D E + E +L ML E + L+F D G VT
Sbjct: 569 ALYKMMLRKKVVLQDMEGVDAEVYNSLNWML---ENSIDGVLDLTFSAD--DERFGEVVT 623
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSC 681
L G +I VT NK E+VE + + + + V F AF GF +I + L +F
Sbjct: 624 VDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLV-TVFDER 682
Query: 682 EVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTG 741
E+E LI G E +D E + T Y+ G+ V++W W+ + + +EQ+ + L F TG
Sbjct: 683 ELELLIGGIAE--IDIEDWKKHTDYR-GYQESDEVIQWFWKCVSEWDNEQRARLLQFTTG 739
Query: 742 SDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+ R+PV G L P + T +G QLP +HTCFN + L +Y D++ +L A
Sbjct: 740 TSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLA 799
Query: 797 LEMYEGYG 804
+E G+G
Sbjct: 800 VEETIGFG 807
>HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 854
Score = 186 bits (471), Expect = 2e-46
Identities = 118/365 (32%), Positives = 190/365 (51%), Gaps = 18/365 (4%)
Query: 446 FRIKVRRSHVTQDSLTSIQ--RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
F +K+ R+++ ++S I + P LK L +EF +E G+D GG+ +EWF LL++E+F+
Sbjct: 497 FEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 556
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P +GLF+Y + N+G L E++ + G V GLA+++ +LD F R
Sbjct: 557 PYYGLFEYSATDNYTLQINPNSG--LCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPF 614
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKP 623
YK + ++IT D E + E +LK +L + +F + E G
Sbjct: 615 YKMMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMFCIDEEN------FGQTYQVD 668
Query: 624 LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEV 683
L G I VT+ENK E+++ + + V +AF GFT ++ L +F E+
Sbjct: 669 LKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDL-IKIFDENEL 727
Query: 684 ERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSD 743
E L+CG D+D R + Y+ G+ PV++W W+ + + E++ + L FVTG+
Sbjct: 728 ELLMCGL--GDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTS 785
Query: 744 RVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALE 798
RVP+ G A L P T GS ++LP AHTCFN L L YE+ + L +L+ A+E
Sbjct: 786 RVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVE 845
Query: 799 MYEGY 803
+G+
Sbjct: 846 NAQGF 850
>Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 955
Score = 186 bits (471), Expect = 2e-46
Identities = 118/365 (32%), Positives = 190/365 (51%), Gaps = 18/365 (4%)
Query: 446 FRIKVRRSHVTQDSLTSIQ--RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
F +K+ R+++ ++S I + P LK L +EF +E G+D GG+ +EWF LL++E+F+
Sbjct: 598 FEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 657
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P +GLF+Y + N+G L E++ + G V GLA+++ +LD F R
Sbjct: 658 PYYGLFEYSATDNYTLQINPNSG--LCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPF 715
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKP 623
YK + ++IT D E + E +LK +L + +F + E G
Sbjct: 716 YKMMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMFCIDEEN------FGQTYQVD 769
Query: 624 LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEV 683
L G I VT+ENK E+++ + + V +AF GFT ++ L +F E+
Sbjct: 770 LKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDL-IKIFDENEL 828
Query: 684 ERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSD 743
E L+CG D+D R + Y+ G+ PV++W W+ + + E++ + L FVTG+
Sbjct: 829 ELLMCGL--GDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTS 886
Query: 744 RVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALE 798
RVP+ G A L P T GS ++LP AHTCFN L L YE+ + L +L+ A+E
Sbjct: 887 RVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVE 946
Query: 799 MYEGY 803
+G+
Sbjct: 947 NAQGF 951
>Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1024
Score = 185 bits (469), Expect = 3e-46
Identities = 113/409 (27%), Positives = 215/409 (51%), Gaps = 23/409 (5%)
Query: 403 YPFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHFRIK------VRRSHVT 456
+PF+ + KI ++ +T +E +A+L++ + + F ++ VRR+H+
Sbjct: 632 FPFIFNNLSKIKLLHTDTLLKIESKKHKAYLRSAAIEEERESEFALRPTFDLTVRRNHLI 691
Query: 457 QDSLTSIQRHPH-DLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEES 515
+D L + + + DL+K L V FS E G D GG+KKE+F L E+ P +G+F Y E +
Sbjct: 692 EDVLNQLSQFENEDLRKELWVSFSGEIGYDLGGVKKEFFYCLFAEMIQPEYGMFMYPEGA 751
Query: 516 RLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFE 575
WF + + + Y+ FGV+ GL+++N + +L F A++KKL ++ + E
Sbjct: 752 SCMWFP-------VKPKFEKKRYFFFGVLCGLSLFNCNVANLPFPLALFKKLLDQMPSLE 804
Query: 576 DYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTS 635
D +EL P+ +NL+ +L +F ++F + +++V N T L G SI V
Sbjct: 805 DLKELSPDLGKNLQTLLDDEGDNFEEVFYI-----HFNVHWDRNDTN-LIPNGSSITVNQ 858
Query: 636 ENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDM 695
NK ++V +++N+ N+ V + + F+ GF ++ + + +F E++ +I G+ D
Sbjct: 859 TNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDI-IKLFHPEELKDVIVGN--TDY 915
Query: 696 DFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPF 755
D++ +Y+ G+++ P + W+ +L+ E++++FL F+TG+DR+ + L +
Sbjct: 916 DWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKI 975
Query: 756 KVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
S + A TCF+ L L +Y + +T+ L A+ G+G
Sbjct: 976 TFCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG 1024
>Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 900
Score = 184 bits (467), Expect = 5e-46
Identities = 120/367 (32%), Positives = 189/367 (50%), Gaps = 22/367 (5%)
Query: 446 FRIKVRRSHVTQDSLTSIQ--RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
F +K+RR+ V +DS I + LK L +EF E G+D GG+ +EWF L+++E+F+
Sbjct: 543 FEMKLRRATVLEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFN 602
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P +GLF+Y + N+G L E++ + G V G+A+Y+ +LD F R
Sbjct: 603 PYYGLFEYSATDNYTLQINPNSG--LCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPF 660
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSY--SELDFSDIFGLSFETTYYDVASGINVT 621
YK + ++ IT D E + E +L+ +L +ELD I + G
Sbjct: 661 YKMMLHKPITLHDMESVDSEYYNSLRWILENDPTELDLRFIID--------EELFGQTHQ 712
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSC 681
L +GG I VT++NK E++ + + + +AF+ GF +I L +F
Sbjct: 713 HELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDL-IKIFDEN 771
Query: 682 EVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTG 741
E+E L+CG D+D R TKY+ G+ V++W W+ + + E++ + L FVTG
Sbjct: 772 ELELLMCGL--GDVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTG 829
Query: 742 SDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+ RVP+ G A L P T G+ ++LP AHTCFN L L YES + L +L A
Sbjct: 830 TSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMA 889
Query: 797 LEMYEGY 803
+E +G+
Sbjct: 890 IENTQGF 896
>Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1572
Score = 182 bits (461), Expect = 2e-45
Identities = 120/367 (32%), Positives = 190/367 (51%), Gaps = 18/367 (4%)
Query: 447 RIKVRRSHVTQDSLTSIQRHPH-DLKKS-LRVEFSNEPGIDAGGLKKEWFLLLTRELFHP 504
++ +RR H+ +D+ I + DL+++ L V F E G+D G +E+F L++RELF+P
Sbjct: 1217 KLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNP 1276
Query: 505 NHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMY 564
+GLF+Y S + + + +N++E + G +LGLA+ + +LD F R Y
Sbjct: 1277 YYGLFEY---SANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFY 1333
Query: 565 KKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPL 624
K L D E L E ++L+ M + D DI L+F T + G + L
Sbjct: 1334 KALLRILCDLSDLEYLDEEFHQSLQWM---KDNDIHDILDLTF--TVNEEVFGQITEREL 1388
Query: 625 CDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVE 684
GG +IPVT +NK E++ER V + + GV + GF V+ D +F + E+E
Sbjct: 1389 KPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVV-DARLVSVFDARELE 1447
Query: 685 RLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDR 744
+I G+ E +D R T+Y+GG+H+ V+ W W + + ++EQ+ + L FVTG+
Sbjct: 1448 LVIAGTAE--IDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSS 1505
Query: 745 VPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEM 799
+P G A+L P + G LP AHTCFN L L Y S L +L+TA+E
Sbjct: 1506 IPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEE 1565
Query: 800 YEGYGFK 806
+G +
Sbjct: 1566 TSTFGLE 1572
>7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1082
Score = 176 bits (447), Expect = 1e-43
Identities = 120/372 (32%), Positives = 185/372 (49%), Gaps = 32/372 (8%)
Query: 446 FRIKVRRSHVTQDSLTSIQRHPHD--LKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
F I++RR+ + +DS I LK L VEF E G+D GGL +EWF LL++E+F+
Sbjct: 725 FEIRIRRTSILEDSYRIISSVTKTDLLKTKLWVEFEGETGLDYGGLAREWFYLLSKEMFN 784
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P +GLF+Y + ++ N G L E + + G + G+A+Y+ +LD F R
Sbjct: 785 PYYGLFEY--SAMDNYTLQINNGSGLCNEEHLSYFKFIGRIAGMAVYHGKLLDAFFIRPF 842
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSYS----ELDF---SDIFGLSFETTYYDVAS 616
YK + + I +D E + E +L + EL F D+FG +
Sbjct: 843 YKMMLQKPIDLKDMESVDTEYYNSLMWIKENDPRILELTFCLDEDVFGQKSQ-------- 894
Query: 617 GINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFP 676
+ KP GG +I VT+ENK E+++ + + V S+F GF +I L
Sbjct: 895 --HELKP---GGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNL-IK 948
Query: 677 MFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFL 736
+F E+E L+CG Q++D + R T Y+G +H +++W W + S+E + + L
Sbjct: 949 IFDEHELELLMCGI--QNIDVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLL 1006
Query: 737 HFVTGSDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLL 791
FVTG+ RVP+ G L P T G+ + P AHTCFN L L YE L
Sbjct: 1007 QFVTGTSRVPMNGFKELYGSNGPQMFTIEKWGTPNNFPRAHTCFNRLDLPPYEGYLQLKD 1066
Query: 792 RLVTALEMYEGY 803
+L+ A+E +G+
Sbjct: 1067 KLIKAIEGSQGF 1078
>SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3227
Score = 176 bits (446), Expect = 1e-43
Identities = 116/368 (31%), Positives = 193/368 (51%), Gaps = 23/368 (6%)
Query: 448 IKVRRSHVTQDSLTSIQRHPHDLKK--SLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPN 505
I VRR HV DS ++ D K L + F +E G+DAGG+ +EW +L R++F+P+
Sbjct: 2872 ITVRRDHVFLDSYRALHFKDADEVKFSKLNIHFRDEEGVDAGGVTREWLQVLARQMFNPD 2931
Query: 506 HGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYK 565
+ LF V ++ ++ + ++ + G ++G A+Y+ +LD HF+RA+YK
Sbjct: 2932 YALFLPVTGDATTFHPNRDSSVN---PDHLSFFKFTGRIIGKALYDGRLLDCHFSRAVYK 2988
Query: 566 KLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLC 625
+ + ++ +D E L P+ ++L ML+ D +DI ++ E G L
Sbjct: 2989 HMLHRSVSVKDIESLDPDYYKSLVWMLNN---DITDI--ITEEFAVEKDVFGEKTVVDLI 3043
Query: 626 DGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVER 685
G +IPVT NK +V R V++ + E V + GF+ +I L +F E+E
Sbjct: 3044 PNGRNIPVTELNKQNYVNRMVDYKLRESVKDQLKSLLDGFSDIIPSHL-IQIFNEQELEL 3102
Query: 686 LICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRV 745
LI G E D+D + T+Y G++ +P V+W W + E++ + L F TG+ +V
Sbjct: 3103 LISGLPEIDID--DWKNNTEYH-GYNVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKV 3159
Query: 746 PVTGLATLP-------FKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTAL- 797
P+ G L F + + + GS ++LP +HTCFN+L L EY++ + L L+TA+
Sbjct: 3160 PLNGFKELEGMSGFQRFNIHK-SYGSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAIN 3218
Query: 798 EMYEGYGF 805
E EG+GF
Sbjct: 3219 EGSEGFGF 3226
>Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 748
Score = 169 bits (429), Expect = 1e-41
Identities = 113/371 (30%), Positives = 187/371 (49%), Gaps = 29/371 (7%)
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H RI+V R + ++S + + P DL K L ++F E G+D GG+ +EW LL+ E+ +
Sbjct: 392 HCRIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLN 451
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P +GLFQY + + ++ + + ++ G ++G+A+++ +D F
Sbjct: 452 PYYGLFQYSRDDIYTLQINPDSAV---NPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPF 508
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKP 623
YK+L + IT +D E + P+ +L +L E D + + +F + A G +
Sbjct: 509 YKQLLGKSITLDDMELVDPDLHNSLVWIL---ENDITGVLDHTFCVEHN--AYGEIIQHE 563
Query: 624 LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEV 683
L G+SIPV ENK E+V +VN+ G+ + F A Q GF VI L F E+
Sbjct: 564 LKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHL-LKTFDEKEL 622
Query: 684 ERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSD 743
E +ICG + D++ ++ K+ N +V+W W+ + E++ + L FVTGS
Sbjct: 623 ELIICGLGKIDVNDWKVNTRLKHCTPDSN---IVKWFWKAVEFFDEERRARLLQFVTGSS 679
Query: 744 RVPVTGLATLPFKVTRTTSGSH-----------DQLPTAHTCFNELCLYEYESRDTLLLR 792
RVP+ G FK + +G + LP AHTCFN + + YES + L +
Sbjct: 680 RVPLQG-----FKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEK 734
Query: 793 LVTALEMYEGY 803
L+TA+E G+
Sbjct: 735 LLTAIEETCGF 745
>Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1606
Score = 169 bits (428), Expect = 2e-41
Identities = 116/369 (31%), Positives = 183/369 (49%), Gaps = 22/369 (5%)
Query: 447 RIKVRRSHVTQDSLTSIQRHPHD--LKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHP 504
++ +RR H+ + + + + + L V F E G+D G +E+F LL++ELF+P
Sbjct: 1251 KLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNP 1310
Query: 505 NHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMY 564
+GLF+Y S + + + EN+ E + G +LGLA+ + +LD F R Y
Sbjct: 1311 YYGLFEY---SANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFY 1367
Query: 565 KKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPL 624
K L D E L E ++L+ M + + +DI L+F T + G + L
Sbjct: 1368 KALLRLPCDLSDLEYLDEEFHQSLQWM---KDNNITDILDLTF--TVNEEVFGQVTEREL 1422
Query: 625 CDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVE 684
GG + VT +NK E++ER V + + GV A GF V+ D +F + E+E
Sbjct: 1423 KSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVV-DSRLVSVFDARELE 1481
Query: 685 RLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDR 744
+I G+ E +D R T+Y+GG+H+ V+ W W + + ++EQ+ + L FVTG+
Sbjct: 1482 LVIAGTAE--IDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSS 1539
Query: 745 VPVTGLATL-------PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTAL 797
VP G A L F + + G LP AHTCFN L L Y S L +L+TA+
Sbjct: 1540 VPYEGFAALRGSNGLRRFCIEKW--GKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAV 1597
Query: 798 EMYEGYGFK 806
E +G +
Sbjct: 1598 EETSTFGLE 1606
>7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 5002
Score = 168 bits (426), Expect = 3e-41
Identities = 129/451 (28%), Positives = 216/451 (47%), Gaps = 41/451 (9%)
Query: 367 KRDFMMWHKMNREQWRTLDDLSMTQLHETHYTALCQYPFLMSLGVKIAIMEFETGKMMEH 426
++ F+ + + +R + S T L + + L + ++ VK + E
Sbjct: 4580 RQKFLQFAEKHRTVLNQILRQSPTHLSDGPFAVLVDHTRILDFDVKRKYFQTE------- 4632
Query: 427 NAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGID 485
L+ LD + H + VRR V +DS + R P + K + F +E G D
Sbjct: 4633 ------LERLDEGIRREEH-TVSVRRVTVFEDSFRVLYRLGPEEWKNRFYIVFEDEEGQD 4685
Query: 486 AGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLF-GVV 544
AGGL +EW+++++RE+F+P + LF R+++ ++ H N+ Y+ F G V
Sbjct: 4686 AGGLLREWYVIISREIFNPMYALFCVSPGDRVTYMINPSS----HANPNHLSYFKFVGRV 4741
Query: 545 LGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFG 604
+ A++++ +L+ +F R+ YK + +++ D E E + L ++ +DI
Sbjct: 4742 IAKAVHDNKLLECYFTRSFYKHILGKQVKHTDMESQDYEFYKGLDYLMK------NDIST 4795
Query: 605 LSFETTYYDVASGINVT--KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQ 662
L +E T+ VT + L G VT ENK E+V+ M+ + AF
Sbjct: 4796 LGYELTFSTEVQEFGVTQIRDLKPNGRDTAVTEENKFEYVQLVCQLKMSGSIRQQLDAFL 4855
Query: 663 SGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWE 722
GF +I L +F E+E LI G D+D E L+A T+Y + +++ ++W W
Sbjct: 4856 EGFYDIIPKHL-ISIFNEQELELLISGL--PDIDIEDLKANTEYH-KYTSKSAQIQWFWR 4911
Query: 723 ILPQLSHEQQRQFLHFVTGSDRVPVTGLATL-------PFKVTRTTSGSHDQLPTAHTCF 775
L + +FL FVTG+ +VP+ G +L F++ R S D+LP AHTCF
Sbjct: 4912 ALRSFDQADRAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQIHR-DDRSTDRLPCAHTCF 4970
Query: 776 NELCLYEYESRDTLLLRLVTAL-EMYEGYGF 805
N+L L Y+S D L L+ A+ E EG+GF
Sbjct: 4971 NQLDLPMYKSYDKLRSCLLKAIHECSEGFGF 5001
>Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 757
Score = 168 bits (425), Expect = 3e-41
Identities = 115/369 (31%), Positives = 186/369 (50%), Gaps = 22/369 (5%)
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H RI+V R + ++S I + P DLKK L V+F E G+D GG+ +EW LL E+ +
Sbjct: 398 HCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLN 457
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P +GLFQY ++ + N ++ ++ + +++ G ++GLA+++ ++ F
Sbjct: 458 PYYGLFQYSTDN--IYMLQINPDSSINPDHLSYFHFV-GRIMGLAVFHGHYINGGFTVPF 514
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKP 623
YK+L + I D E + PE ++L +L E D + + +F + A G +
Sbjct: 515 YKQLLGKPIQLSDLESVDPELHKSLVWIL---ENDITPVLDHTFCVEHN--AFGRILQHE 569
Query: 624 LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEV 683
L G ++PVT ENK E+V +VN+ G+ + F A Q GF +I L P F E+
Sbjct: 570 LKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKP-FDQKEL 628
Query: 684 ERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSD 743
E +I G + D++ + K+ N +V W W+ + E++ + L FVTGS
Sbjct: 629 ELIIGGLDKIDLNDWKSNTRLKHCVADSN---IVRWFWQAVETFDEERRARLLQFVTGST 685
Query: 744 RVPV---------TGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLV 794
RVP+ TG A + D LP AHTCFN + + YES + L +L+
Sbjct: 686 RVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLL 745
Query: 795 TALEMYEGY 803
TA+E G+
Sbjct: 746 TAVEETCGF 754
>CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 875
Score = 168 bits (425), Expect = 3e-41
Identities = 127/419 (30%), Positives = 200/419 (47%), Gaps = 34/419 (8%)
Query: 397 YTALCQYPFLMSLGVKIAIMEFETGKMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVT 456
+ L Q+P L+ VK E K+ ++ + DV ++V R+ V
Sbjct: 480 FAILTQFPKLLDFDVKRKYFRKELTKLEP---------SMPRYRRNDVS--VQVSRNRVF 528
Query: 457 QDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEES 515
DS + R P + K + F E G DAGGL +EWF ++TRE+F+PN+ LF
Sbjct: 529 SDSFRELFRLRPSEWKNRFYIIFQGEEGQDAGGLLREWFSVITREIFNPNYALFITAPGD 588
Query: 516 RLSWFAYGNTGLKLHGENNNELYYLF-GVVLGLAIYNSTILDLHFARAMYKKLCNERITF 574
+++ N ++ E+ + Y+ F G ++ +++ LD +F RA YK + N + +
Sbjct: 589 MVTYMI--NKASYINPEHLD--YFKFVGRLIAKSVFEHKYLDCYFTRAFYKHILNLPVRY 644
Query: 575 EDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVT 634
+D E P ++L +L D + L+F T + G+ + L G I V
Sbjct: 645 QDLESEDPAFFKSLDFLLQNPIDDLA--LDLTFSTEVEEF--GVRSVRDLKPNGRKIEVN 700
Query: 635 SENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQD 694
NK E+V+ M + AF +GF +I L MF E+E LI G
Sbjct: 701 DANKDEYVKLVCQMKMTGSIRKQLDAFLTGFYEIIPKDL-ISMFNEQELELLISGL--PT 757
Query: 695 MDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL- 753
+D + + A T Y+ GF + ++W W L E + +FL FVTG+ +VP+ G A+L
Sbjct: 758 VDIDDMAANTDYK-GFQKTSTHIQWFWRALRSFEKEDKAKFLQFVTGTSKVPLQGFASLE 816
Query: 754 ------PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTAL-EMYEGYGF 805
F + + G D+LP AHTCFN+L L +YES + L L+ A+ E EG+GF
Sbjct: 817 GMNGVQKFSIHMDSRGG-DRLPAAHTCFNQLDLPQYESYEKLRQSLLLAIRECTEGFGF 874
>7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 388
Score = 167 bits (424), Expect = 5e-41
Identities = 112/361 (31%), Positives = 187/361 (51%), Gaps = 16/361 (4%)
Query: 453 SHVTQDSLTSIQR-HPHDLKKS-LRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQ 510
+H+ +D+ I + DL++ L V + E G+D GG +E+F LL+RELF+P +GLF+
Sbjct: 37 NHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGLDYGGPSREFFFLLSRELFNPYYGLFE 96
Query: 511 YVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNE 570
Y S + + L +N ++ + G VLGLA+ + +LD F R YK L
Sbjct: 97 Y---SANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLRL 153
Query: 571 RITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGES 630
+ D E L E ++L+ + +++ GL+F T + G V + L GG++
Sbjct: 154 PVALSDLESLDNEFHQSLQ-WIRDNDIGTGVDLGLTFCVT--EELLGSVVDRELKPGGKN 210
Query: 631 IPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGS 690
I + +NK E++ER + + + GV + GF VI D +F + E+E +I G+
Sbjct: 211 IIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVI-DSRLVSVFDARELELVIAGT 269
Query: 691 IEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGL 750
E +D R T+Y+ G+H+ V+ W W+++ + S+EQ+ + L FVTG+ +P G
Sbjct: 270 AE--IDTNDWRLNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGF 327
Query: 751 ATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYGF 805
+ L P + G + LP AHTCFN L L Y + + L +L+ A+E +G
Sbjct: 328 SALRGSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTFGI 387
Query: 806 K 806
+
Sbjct: 388 E 388
>SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 671
Score = 165 bits (418), Expect = 2e-40
Identities = 112/391 (28%), Positives = 195/391 (49%), Gaps = 28/391 (7%)
Query: 425 EHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPG 483
E+ + A++ + D ++KV R+ +D+ I + D+KK L + F NE G
Sbjct: 296 EYQRKIAYMYDRPEMAVNDAQLQLKVSRATTFEDAYDIISKLSVSDMKKKLLIRFRNEDG 355
Query: 484 IDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNN-ELYYLF- 541
+D GG+ +E+F +L+ +F+P + LF+Y + YG L N + Y+ F
Sbjct: 356 LDYGGVSREFFYILSHAIFNPGYSLFEYATDDN-----YGLQISPLSSVNPDFRSYFRFV 410
Query: 542 GVVLGLAIYNSTILDLHFARAMYKKLCNERITFE---DYEELYPETARNLKKMLSYSELD 598
G V+GLAIY+ LD+ F YK++ + + E D +E+Y E+ + +K +++D
Sbjct: 411 GRVMGLAIYHRRYLDVQFVLPFYKRILQKPLCLEDVKDVDEVYYESLKWIKN----NDVD 466
Query: 599 FSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSF 658
S S E + G +VT L G +I V ++NK +++ + F
Sbjct: 467 ESLCLNFSVEENRF----GESVTVDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQF 522
Query: 659 SAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVE 718
+A + G +I D + +F E++ L+ G ++D+D + + T Y+ + +V
Sbjct: 523 NALKGGLNELIPDSV-LQIFNENELDTLLNG--KRDIDVQDWKRFTDYR-SYTETDDIVI 578
Query: 719 WLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHT 773
W WE+L + S E++ + L F TG+ R+P++G + P K T G QLP AHT
Sbjct: 579 WFWELLSEWSPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTIEKVGHISQLPKAHT 638
Query: 774 CFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
CFN L + Y S++ L +L A++ G+G
Sbjct: 639 CFNRLDIPPYNSKEELEQKLTIAIQETAGFG 669
>Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 165 bits (417), Expect = 3e-40
Identities = 111/369 (30%), Positives = 184/369 (49%), Gaps = 23/369 (6%)
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H +I V R + +DS I P+DL++ L + E G+D GG+ +EWF LL+ E+ +
Sbjct: 514 HVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLN 573
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P + LF+Y ++ ++ N ++ ++ ++ G + +A+Y+ +D F
Sbjct: 574 PMYCLFEYAGKN--NYCLQINPASSINPDHLTYFRFI-GRFIAMALYHGKFIDTGFTLPF 630
Query: 564 YKKLCNERITFEDYEELYPETARNLK--KMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
YK++ N+R T +D E + PE ++ K + E F E G T
Sbjct: 631 YKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEIL------GKVTT 684
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIG-DGLAFPMFKS 680
L +GGESI VT ENK E++ ++ GV AF GF V + L + F
Sbjct: 685 HELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRY--FDE 742
Query: 681 CEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVT 740
E+E ++CG E DM Q + ++ + + ++W W+++ ++ +E++ + L FVT
Sbjct: 743 KELELMLCGMQEIDMSDWQKSTIYRH---YTKNSKQIQWFWQVVKEMDNEKRIRLLQFVT 799
Query: 741 GSDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVT 795
G+ R+PV G A L P K G LP +HTCFN L L Y+S + L +L+
Sbjct: 800 GTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLY 859
Query: 796 ALEMYEGYG 804
A+E EG+G
Sbjct: 860 AIEETEGFG 868
>Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 165 bits (417), Expect = 3e-40
Identities = 111/369 (30%), Positives = 184/369 (49%), Gaps = 23/369 (6%)
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H +I V R + +DS I P+DL++ L + E G+D GG+ +EWF LL+ E+ +
Sbjct: 514 HVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLN 573
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P + LF+Y ++ ++ N ++ ++ ++ G + +A+Y+ +D F
Sbjct: 574 PMYCLFEYAGKN--NYCLQINPASSINPDHLTYFRFI-GRFIAMALYHGKFIDTGFTLPF 630
Query: 564 YKKLCNERITFEDYEELYPETARNLK--KMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
YK++ N+R T +D E + PE ++ K + E F E G T
Sbjct: 631 YKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEIL------GKVTT 684
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIG-DGLAFPMFKS 680
L +GGESI VT ENK E++ ++ GV AF GF V + L + F
Sbjct: 685 HELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRY--FDE 742
Query: 681 CEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVT 740
E+E ++CG E DM Q + ++ + + ++W W+++ ++ +E++ + L FVT
Sbjct: 743 KELELMLCGMQEIDMSDWQKSTIYRH---YTKNSKQIQWFWQVVKEMDNEKRIRLLQFVT 799
Query: 741 GSDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVT 795
G+ R+PV G A L P K G LP +HTCFN L L Y+S + L +L+
Sbjct: 800 GTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLY 859
Query: 796 ALEMYEGYG 804
A+E EG+G
Sbjct: 860 AIEETEGFG 868
>CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 817
Score = 164 bits (415), Expect = 5e-40
Identities = 124/395 (31%), Positives = 185/395 (46%), Gaps = 52/395 (13%)
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H +I V R++V +DS I R + DL++ L ++F E G+D GG+ +EWF LL+ E+ +
Sbjct: 438 HVKITVSRNNVFEDSFQEIMRKNAVDLRRRLYIQFRGEEGLDYGGVAREWFFLLSHEVLN 497
Query: 504 PNHGLFQY---------------VEESRLSWFAYGNTGLKLHGENNN-------ELYYLF 541
P + LF Y V L +F Y + + + N + Y F
Sbjct: 498 PMYCLFMYAGNNNYSLQINPASFVNPDHLKYFEYIGRFIAMLKKPGNFDDLKFSDQYISF 557
Query: 542 GVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLK--KMLSYSELDF 599
A+++ + F YKK+ N++I +D E++ E +L K + E D
Sbjct: 558 SP--KNALFHGKFIYSGFTMPFYKKMLNKKIVLKDIEQVDSEIYNSLMWIKDNNIDECDM 615
Query: 600 SDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFS 659
F +E G T L +GG I VT ENK E++E V + N GV
Sbjct: 616 ELYFVADYELL------GELKTYELKEGGTEIAVTEENKLEYIELLVEWRFNRGVEQQTK 669
Query: 660 AFQSGFTRVIGDGLAFPM-----FKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQT 714
AF +GF V FP+ F E+E L+CG + D+D Q V ++ + Q+
Sbjct: 670 AFFTGFNSV------FPLEWMQYFDERELELLLCGMQDVDVDDWQRNTVYRH---YAPQS 720
Query: 715 PVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL-----PFKVTRTTSGSHDQLP 769
V W W+ + L E++ + L FVTG+ RVPV G + L P G + LP
Sbjct: 721 KQVTWFWQWVRSLDQEKRARLLQFVTGTCRVPVGGFSELMGSTGPQLFCIERVGKENWLP 780
Query: 770 TAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
+HTCFN L L Y S D L+ +L A+EM EG+G
Sbjct: 781 RSHTCFNRLDLPPYRSYDQLVEKLSMAIEMTEGFG 815
>7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 949
Score = 164 bits (414), Expect = 7e-40
Identities = 116/373 (31%), Positives = 183/373 (48%), Gaps = 33/373 (8%)
Query: 445 HFRIKVRRSHVTQDSLTSIQRHP-HDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H +I V R + +DS I R P ++L++ L + F E G+D GG+ +EWF LL+ E+ +
Sbjct: 593 HIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLN 652
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGE---NNNELYY--LFGVVLGLAIYNSTILDLH 558
P + LF+Y ++ N L+++ N + L Y G + +A+Y+ +
Sbjct: 653 PMYCLFEYANKN--------NYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSG 704
Query: 559 FARAMYKKLCNERITFEDYEELYPETARNL--KKMLSYSELDFSDIFGLSFETTYYDVAS 616
F YK++ N+++T +D E + PE +L K + E F + FE
Sbjct: 705 FTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVL------ 758
Query: 617 GINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIG-DGLAF 675
G + L + GE VT ENK E++ + M G+ F GF V+ + L +
Sbjct: 759 GQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKY 818
Query: 676 PMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQF 735
F E+E ++CG QD+D E + T Y+ N VV W W+ + + +E++ +
Sbjct: 819 --FDERELELILCGM--QDVDVEDWQRNTIYRHYNRNSKQVV-WFWQFVRETDNEKRARL 873
Query: 736 LHFVTGSDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLL 790
L FVTG+ RVPV G A L P + G LP +HTCFN L L Y+S D L+
Sbjct: 874 LQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLV 933
Query: 791 LRLVTALEMYEGY 803
+L A+E EG+
Sbjct: 934 EKLTFAIEETEGF 946
>YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3268
Score = 162 bits (411), Expect = 1e-39
Identities = 116/369 (31%), Positives = 190/369 (51%), Gaps = 27/369 (7%)
Query: 448 IKVRRSHVTQDSLTSIQRHPHDLKKSLRVE--FSNEPGIDAGGLKKEWFLLLTRELFHPN 505
I VRR V DS ++ +D K+ ++E F E G+DAGG+ +EW+ +L+R++F+P+
Sbjct: 2913 ITVRREQVFLDSYRALFFKTNDEIKNSKLEITFKGESGVDAGGVTREWYQVLSRQMFNPD 2972
Query: 506 HGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYK 565
+ LF V + ++ +G+ + + G+++G AI + LD HF+R +YK
Sbjct: 2973 YALFLPVPSDKTTFHPNRTSGI---NPEHLSFFKFIGMIIGKAIRDQCFLDCHFSREVYK 3029
Query: 566 KLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSF--ETTYYDVASGINVTKP 623
+ ++ +D E L P+ ++L +L E D +DI +F ET Y IN
Sbjct: 3030 NILGRPVSLKDMESLDPDYYKSLVWIL---ENDITDIIEETFSVETDDYGEHKVIN---- 3082
Query: 624 LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEV 683
L +GG+ I VT NK ++V++ V + + V F GF +I L +F E+
Sbjct: 3083 LIEGGKDIIVTEANKQDYVKKVVEYKLQTSVKEQMDNFLVGFYALISKDL-ITIFDEQEL 3141
Query: 684 ERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSD 743
E LI G D+D + + T Y + V + W + E++ + L FVTG+
Sbjct: 3142 ELLISGL--PDIDVDDWKNNTTYV-NYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTS 3198
Query: 744 RVPVTGLATL-------PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+VP+ G L F + R GS ++LP++HTCFN+L L YES +TL L+ A
Sbjct: 3199 KVPLNGFKELSGVNGVCKFSIHR-DFGSSERLPSSHTCFNQLNLPPYESYETLRGSLLLA 3257
Query: 797 L-EMYEGYG 804
+ E +EG+G
Sbjct: 3258 INEGHEGFG 3266
>Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase
Length = 379
Score = 162 bits (410), Expect = 2e-39
Identities = 102/359 (28%), Positives = 182/359 (50%), Gaps = 17/359 (4%)
Query: 446 FRIKVRRSHVTQDSLTSI-QRHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHP 504
F ++VRRS + +D+L + Q D K L VEF NE ++GG+ E+F + E+ P
Sbjct: 29 FILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKP 88
Query: 505 NHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMY 564
+G+F Y E WF + + Y+LFG++ GL+++N + +L F A+Y
Sbjct: 89 EYGMFMYPEMCSCMWFP-------AKPKPEKKRYFLFGMLCGLSLFNLNVANLPFPLALY 141
Query: 565 KKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPL 624
KKL +++ + ED +EL P ++L+++L + D D + F + ++D L
Sbjct: 142 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCIRF-SIHWDQND-----VDL 195
Query: 625 CDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVE 684
G SIPV NK ++V +++++ N V + + FQ GF RV + + E+
Sbjct: 196 IPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPE-ELM 254
Query: 685 RLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDR 744
I G+ D D++Q +KY+ G+ P ++ W+ +L+ +++++FL F+TG DR
Sbjct: 255 TAIIGNT--DYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDR 312
Query: 745 VPVTGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGY 803
+ G+ + + S PT+ TC N L L +Y + + + L A+ G+
Sbjct: 313 LHARGIQKMEIVFRCPETFSERDHPTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 371
>ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 2410
Score = 161 bits (408), Expect = 3e-39
Identities = 113/372 (30%), Positives = 186/372 (49%), Gaps = 27/372 (7%)
Query: 446 FRIKVRRSHVTQDSLTSIQ-RHPHDLK-KSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
+R+ V RS V + S + + P + + + L ++ + E G+D GGL +EW +LL ++L
Sbjct: 2053 YRVYVDRSDVLRSSYFQVMAKSPEEFRTRRLEIKLTGEEGLDYGGLTREWLVLLAKDLLD 2112
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYY--LFGVVLGLAIYNSTILDLHFAR 561
PN LF++ E + + N+ + N L Y G ++ AI + ++LH ++
Sbjct: 2113 PNFALFEFATEDKTTVVPCKNSYV-----NPEHLSYFKFVGRIIAKAIMDGNFINLHLSK 2167
Query: 562 AMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
+Y+ + + +D E PE ++L + + +D S G++F ++ DV+ G++ T
Sbjct: 2168 FIYQYILGKSCDLQDLESADPEFHKSL-VWIRDNPVDKS--LGITF--SFDDVSFGVHRT 2222
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSC 681
L +GG + V NK E+V+ + + G+ SA +SG ++G A MF
Sbjct: 2223 VELVEGGAHVFVDDSNKAEYVKLATQYRLFNGIELQLSALKSGLFEILG-SKALEMFDES 2281
Query: 682 EVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTG 741
E+E LICG D+D + + T Y G N V+ W W + L + + L FVTG
Sbjct: 2282 ELELLICGI--PDIDVDDWKNNTLYYGYAENSKTVI-WFWRAVKSLDSVSRAKLLQFVTG 2338
Query: 742 SDRVPVTGLATL-------PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLV 794
+ +P G + L F + + S D LPTAHTCFN+L L EY S + LL L
Sbjct: 2339 TSTLPFEGFSHLQGNNEVQKFSIHK-VSDRIDSLPTAHTCFNQLVLPEYSSYENLLKYLT 2397
Query: 795 TAL-EMYEGYGF 805
A+ E G+GF
Sbjct: 2398 LAINECSTGFGF 2409
>At3g17205 [O] KOG0942 E3 ubiquitin protein ligase
Length = 873
Score = 160 bits (406), Expect = 6e-39
Identities = 125/450 (27%), Positives = 202/450 (44%), Gaps = 43/450 (9%)
Query: 377 NREQWRTLDDLSMTQLHETHYTA-----------LCQYPFLMSLGVKIAIMEFETGKMME 425
NR+Q+ + D ++E + L Q PFL+ ++ I + +
Sbjct: 441 NRKQFTSSSDFQADSVNEYFISQAIMEGTRANYILMQAPFLIPFTSRVKIFTTQLATARQ 500
Query: 426 HNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNE--- 481
+ Q R ++RR H+ +D+ + DL+ S+RV F NE
Sbjct: 501 SHGSQGIF----------ARNRFRIRRDHILEDAYNQMSALSEDDLRSSIRVTFVNELGV 550
Query: 482 --PGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYY 539
GID GG+ K++ +TR F +GLF+ + L Y N G + E + + ++
Sbjct: 551 EEAGIDGGGIFKDFMEKITRAAFDVQYGLFKETADHML----YPNPGSGMIHEQHLQFFH 606
Query: 540 LFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDF 599
G +L A++ ++D+ FA KL + D L PE R+L + Y
Sbjct: 607 FLGSLLAKAMFEGILVDIPFATFFLSKLKQKYNYLNDLPSLDPELYRHLIFLKRYK---- 662
Query: 600 SDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFS 659
DI L + G + L GG+ + VT+EN F+ N +N + S
Sbjct: 663 GDISDLELYFVILNNEYGERTEEELLPGGQDMRVTNENVITFIHLVSNHRLNFQIRQQSS 722
Query: 660 AFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEW 719
F GF ++I MF E++ LI GS++ +D + LR T Y GG+H V++
Sbjct: 723 HFLRGFQQLIPKEW-IDMFNEHELQVLISGSVDS-LDIDDLRNNTNYAGGYHAGHYVIDM 780
Query: 720 LWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL--PFKVTR----TTSGSHDQLPTAHT 773
WE++ S E Q++FL FVTG R P+ G L F + R ++ S D+LPT+ T
Sbjct: 781 FWEVMKSFSTENQKKFLKFVTGCSRGPLLGFKYLEPAFCIQRAAGSASNESVDRLPTSAT 840
Query: 774 CFNELCLYEYESRDTLLLRLVTALEMYEGY 803
C N L L Y+S++ L +L+ A+ G+
Sbjct: 841 CMNLLKLPPYQSKELLETKLMYAISAEAGF 870
>HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 862
Score = 160 bits (404), Expect = 9e-39
Identities = 107/368 (29%), Positives = 178/368 (48%), Gaps = 21/368 (5%)
Query: 445 HFRIKVRRSHVTQDSLTSIQRH-PHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H +I V R + +DS I P DL++ L V F E G+D GG+ +EWF LL+ E+ +
Sbjct: 506 HIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLN 565
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P + LF+Y + + ++ + + G + +A+++ +D F+
Sbjct: 566 PMYCLFEYAGKDN---YCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPF 622
Query: 564 YKKLCNERITFEDYEELYPETARNL--KKMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
YK++ N+ + +D E + PE +L K + E D F + E G +
Sbjct: 623 YKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEIL------GEIKS 676
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSC 681
L G +I VT ENK E++ + ++ GV AF GF ++ F +
Sbjct: 677 HDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQY-LQYFDAK 735
Query: 682 EVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTG 741
E+E L+CG E D++ Q A+ ++ Q + W W+ + ++ +E++ + L FVTG
Sbjct: 736 ELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQ---IMWFWQFVKEIDNEKRMRLLQFVTG 792
Query: 742 SDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+ R+PV G A L P K G + LP +HTCFN L L Y+S + L +L+ A
Sbjct: 793 TCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFA 852
Query: 797 LEMYEGYG 804
+E EG+G
Sbjct: 853 IEETEGFG 860
>Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 903
Score = 160 bits (404), Expect = 9e-39
Identities = 107/368 (29%), Positives = 178/368 (48%), Gaps = 21/368 (5%)
Query: 445 HFRIKVRRSHVTQDSLTSIQRH-PHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H +I V R + +DS I P DL++ L V F E G+D GG+ +EWF LL+ E+ +
Sbjct: 547 HIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLN 606
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P + LF+Y + + ++ + + G + +A+++ +D F+
Sbjct: 607 PMYCLFEYAGKDN---YCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPF 663
Query: 564 YKKLCNERITFEDYEELYPETARNL--KKMLSYSELDFSDIFGLSFETTYYDVASGINVT 621
YK++ N+ + +D E + PE +L K + E D F + E G +
Sbjct: 664 YKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEIL------GEIKS 717
Query: 622 KPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSC 681
L G +I VT ENK E++ + ++ GV AF GF ++ F +
Sbjct: 718 HDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQY-LQYFDAK 776
Query: 682 EVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTG 741
E+E L+CG E D++ Q A+ ++ Q + W W+ + ++ +E++ + L FVTG
Sbjct: 777 ELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQ---IMWFWQFVKEIDNEKRMRLLQFVTG 833
Query: 742 SDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+ R+PV G A L P K G + LP +HTCFN L L Y+S + L +L+ A
Sbjct: 834 TCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFA 893
Query: 797 LEMYEGYG 804
+E EG+G
Sbjct: 894 IEETEGFG 901
>7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1017
Score = 157 bits (396), Expect = 8e-38
Identities = 120/370 (32%), Positives = 175/370 (46%), Gaps = 49/370 (13%)
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H R++V R+ + ++S I + D++K L V+F E G+D GG+ +EW LL+RE+ +
Sbjct: 683 HCRLEVSRNEIFEESYRLIMKMRAKDMRKRLMVKFKGEEGLDYGGVAREWLHLLSREMLN 742
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
P +GLFQY + + ++G+ N + L Y HF
Sbjct: 743 PQYGLFQYSRDDHYTLQINPDSGV-----NPDHLSY-----------------FHF---- 776
Query: 564 YKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKP 623
L N+ IT D E + P+ R+L ML E + S I +F + + G V
Sbjct: 777 ---LLNKPITLGDIEGVDPDLHRSLTWML---ESNISGIIESTFSVE--NNSFGALVVHE 828
Query: 624 LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEV 683
L GG SIPVT ENK E+V+ +VN+ G+ F A Q GF +I L P F E+
Sbjct: 829 LKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRP-FDEREL 887
Query: 684 ERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSD 743
E L+ G I +D R T+ + N+T V W W+++ S E + + L FVTGS
Sbjct: 888 E-LVIGGI-SSIDVNDWRNNTRLK-HCTNETTQVLWFWQVVESYSSEMRARLLQFVTGSS 944
Query: 744 RVPVTGLATLP----------FKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRL 793
RVP+ G L F + T LP AHTCFN + L YE+ L +L
Sbjct: 945 RVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQNLPKAHTCFNRIDLPPYETYQLLCDKL 1004
Query: 794 VTALEMYEGY 803
A+E G+
Sbjct: 1005 TQAVEETCGF 1014
>SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase
Length = 1029
Score = 156 bits (395), Expect = 1e-37
Identities = 108/362 (29%), Positives = 166/362 (45%), Gaps = 15/362 (4%)
Query: 450 VRRSHVTQDSLTSIQRHPHDLKKSLRVEFSNE-----PGIDAGGLKKEWFLLLTRELFHP 504
+RR+ + D + LK +R+ F +E GID GGL KE+ + + +F
Sbjct: 676 IRRNRIFDDGFDAFYNFGKLLKGPIRITFVDEHGVVEEGIDGGGLTKEFLTSICKTVFDI 735
Query: 505 NHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMY 564
N+GLF + L Y NT Y G+++G IY +D FA
Sbjct: 736 NYGLFSETKAHLL----YPNTHAYAQDVERLRCYEFLGMLIGKCIYEGIQIDAAFASFFV 791
Query: 565 KKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPL 624
K F+D L P L + +Y D + L+F + + G+ L
Sbjct: 792 AKWLGHPSYFDDLTSLDPNLYEGLVFLKNYDG-DVENDMALNFTVVHEEF--GVRNVIDL 848
Query: 625 CDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVE 684
G +I VT+EN+ +++ N+Y+N +S AF +GFT++I D MF E++
Sbjct: 849 IPNGSNISVTNENRLQYIHLVSNYYLNARLSRQCRAFTNGFTQII-DPHWLAMFHESEIQ 907
Query: 685 RLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDR 744
L+ G +D + LR T Y GG+ +P + WE+L + E +R F+ FVT R
Sbjct: 908 ILVGGD-PVPIDIDDLRRHTVYAGGYEPNSPTIVLFWEVLREFEEEDKRSFVKFVTSVAR 966
Query: 745 VPVTGL-ATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGY 803
P+ G A +P R +LPTA TC N L L Y ++ TL +L+TA+ G+
Sbjct: 967 PPILGFKALMPSFCIRVNGEDETRLPTASTCVNLLKLPMYSTKQTLRDKLLTAVRSGVGF 1026
Query: 804 GF 805
GF
Sbjct: 1027 GF 1028
>7291760 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1122
Score = 156 bits (395), Expect = 1e-37
Identities = 126/448 (28%), Positives = 211/448 (46%), Gaps = 34/448 (7%)
Query: 368 RDFMMWHKMNREQWRTLDDLSMTQLHETHYTALCQYPFLMSLGVKIAIME--FETGKMME 425
R F RE + +S Q+ T L + PF++ +++I++ KM
Sbjct: 694 RPFQPIRDFTREDFENGPPMSTKQIRSI--TILREIPFVVPFNKRVSILQSLVAASKMRV 751
Query: 426 HNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSN---- 480
QAFL+ I VRRSH+ +D+ ++ + DL+ R++F +
Sbjct: 752 QGNMQAFLQGPS--------VLITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGL 803
Query: 481 -EPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYY 539
E GID GG+ +E+ L + F PN G F +++L Y N + E+ + YY
Sbjct: 804 DEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDNKL----YPNPNVADLFEDYEKHYY 859
Query: 540 LFGVVLGLAIYNSTILDLHFARAMYKKLCNER--ITFEDYEELYPETARNLKKMLSYSEL 597
G +LG +IY + +++L A KL + + L PE RNL + YS
Sbjct: 860 FIGRILGKSIYENLLVELPLAEFFLTKLAGKYSDVDIHQLASLDPELYRNLLYLKDYS-- 917
Query: 598 DFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSS 657
D+ L+ + T + G L G+SIPVT+ N+ E+++ ++ +N +
Sbjct: 918 --GDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRH 975
Query: 658 FSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVV 717
+AF+ G + V+ + MF + E++ LI G+ E +D E L+ +Y G F + P +
Sbjct: 976 CNAFRKGLSNVLPIEWLY-MFSNKELQILISGA-EIPIDLEDLKKHCEYGGEFSPEHPSI 1033
Query: 718 EWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL--PFKVTRTTSGSHDQLPTAHTCF 775
WE+L Q+RQ L FVT R P+ G L PF + T G ++LPTA TC
Sbjct: 1034 VTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPPFFIQNT--GDMERLPTASTCT 1091
Query: 776 NELCLYEYESRDTLLLRLVTALEMYEGY 803
N L L +++ + + +L+ A++ G+
Sbjct: 1092 NLLKLPPFKTVEQMREKLLYAIQSGAGF 1119
>CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 889
Score = 154 bits (389), Expect = 5e-37
Identities = 119/411 (28%), Positives = 194/411 (46%), Gaps = 28/411 (6%)
Query: 407 MSLGVKIAIMEFETGKMM-EHNAEQAFLKALDSRKLYDVHFRI--KVRRSHVTQDSLTSI 463
+ + + +++++ T K+ E + + F + + KL R+ KV R + D+ I
Sbjct: 478 LDITLALSMLDSNTEKLAGEGDNIKMFYEDMKKEKLGKGPSRLCWKVSRDRLLDDAFRII 537
Query: 464 QR-HPHDLKKS-LRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYV-EESRLSWF 520
P LKKS L + F E +D GGL +E+F+LL+RELFHP +G F+Y + L
Sbjct: 538 LNVDPFVLKKSRLHIRFEGELALDYGGLSREFFILLSRELFHPKNGYFEYEGNDYHLQLR 597
Query: 521 AYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEEL 580
G E + L G VL LA+ + +D+ F YK L +T D++E
Sbjct: 598 PRG-----CETEKEKKWLILCGRVLALAVIHRCYIDVFFTNVFYKSLQKRPVTLMDFKES 652
Query: 581 YPETARNLKKMLSYSELDFSDIFGLSF----ETTYYDVASGINVTKPLCD-----GGESI 631
E +++ +L +D F S + + ++S ++V L + GGES
Sbjct: 653 DAEFYKSMNWLLENDVVDLEMSFVYSSMVNGKVSDLTLSSIVSVALQLAEQELVPGGESQ 712
Query: 632 PVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSI 691
VT NK EF++ GV + F +++ D L +S +++R++ GS+
Sbjct: 713 MVTEANKAEFIDLMCQKKAIRGVEKPLEILLTSFNQILNDNL-LNSLESSDLKRILSGSL 771
Query: 692 EQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLA 751
E +D R T Y+GG+ + VVEW WE++ ++++++ L FVTGS VP G +
Sbjct: 772 E--LDLNDWRTNTIYKGGYSDCHIVVEWFWEVIETMTNQERFDLLLFVTGSSSVPFEGFS 829
Query: 752 TLP-----FKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTAL 797
L K G P AHTCFN L L Y ++ L +L A+
Sbjct: 830 ALRGNEEISKFCIEKWGDATSFPRAHTCFNRLQLPSYNTKQQLKSKLQQAI 880
>Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 922
Score = 152 bits (385), Expect = 2e-36
Identities = 109/370 (29%), Positives = 184/370 (49%), Gaps = 25/370 (6%)
Query: 445 HFRIKVRRSHVTQDSLTSIQR-HPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H +I V R + +DS I P+DL++ L V F E G+D GGL +EWF LL+ E+ +
Sbjct: 566 HVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLN 625
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLF-GVVLGLAIYNSTILDLHFARA 562
P + LF+Y ++ ++ N ++ ++ + Y+ F G + +A+++ +D F+
Sbjct: 626 PMYCLFEYAGKN--NYCLQINPASTINPDHLS--YFCFIGRFIAMALFHGKFIDTGFSLP 681
Query: 563 MYKKLCNERITFEDYEELYPETARNL--KKMLSYSELDFSDIFGLSFETTYYDVASGINV 620
YK++ ++++T +D E + E +L + + E F + E G
Sbjct: 682 FYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEIL------GKVT 735
Query: 621 TKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIG-DGLAFPMFK 679
+ L GG +I VT ENK E++ + + GV AF GF V+ L + F
Sbjct: 736 SHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQY--FD 793
Query: 680 SCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFV 739
E+E ++CG Q++D + T Y+ N ++ W W+ + + +E + + L FV
Sbjct: 794 EKELEVMLCGM--QEVDLADWQRNTVYRHYTRNSKQII-WFWQFVKETDNEVRMRLLQFV 850
Query: 740 TGSDRVPVTGLATL-----PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLV 794
TG+ R+P+ G A L P K G LP +HTCFN L L Y+S + L +L+
Sbjct: 851 TGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLL 910
Query: 795 TALEMYEGYG 804
A+E EG+G
Sbjct: 911 FAIEETEGFG 920
>Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 562
Score = 147 bits (372), Expect = 5e-35
Identities = 105/343 (30%), Positives = 168/343 (48%), Gaps = 21/343 (6%)
Query: 470 LKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKL 529
LK+ + V F E G+ G + +EWF +L+ E+ +P++ LF +S N+ +
Sbjct: 231 LKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFT---QSADGTTFQPNSNSYV 286
Query: 530 HGENNNELYYLF-GVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNL 588
+ ++ N Y+ F G +LGLA+ + +++++F R+ YK + + ++D + PE A+NL
Sbjct: 287 NPDHLN--YFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNL 344
Query: 589 KKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNF 648
+ +L D S ET + + PL GG SI VT NK E+V+
Sbjct: 345 QWILDNDISDLGLELTFSVETDVFGAMEEV----PLKPGGGSILVTQNNKAEYVQLVTEL 400
Query: 649 YMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQG 708
M + +AF GF I L +F E+E L+ G E +D T+Y
Sbjct: 401 RMTRAIQPQINAFLQGFHMFIPPSL-IQLFDEYELELLLSGMPE--IDVSDWIKNTEYTS 457
Query: 709 GFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLAT------LPFKVTRTTS 762
G+ + PV++W WE++ ++ E++ L FVTGS RVP G A L
Sbjct: 458 GYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVP 517
Query: 763 GSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYGF 805
+ + LPT+ TC N L L EY S++ L RL+ AL YG+
Sbjct: 518 YTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHC-GSYGY 559
>Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1068
Score = 147 bits (371), Expect = 6e-35
Identities = 120/391 (30%), Positives = 182/391 (45%), Gaps = 43/391 (10%)
Query: 448 IKVRRSHVTQDSLTSI-QRHPHDLKKSLRVEFSN-----EPGIDAGGLKKEWFLLLTREL 501
I +RRS + +D + Q H +K +RV+F N E GID G+ KE+ + + +
Sbjct: 683 ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRV 742
Query: 502 FHPNHGLFQYVE-ESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFA 560
F P LF+ + RL Y + +H EN +L+ G +LG A+Y ++D+ FA
Sbjct: 743 FDPALNLFKTTSGDERL----YPSPTSYIH-ENYLQLFEFVGKMLGKAVYEGIVVDVPFA 797
Query: 561 RAMYKKLCNER--ITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGI 618
+L + + +EL + K + S D DI L +Y + G
Sbjct: 798 SFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYD-GDITDLGLTLSYDEDVMGQ 856
Query: 619 NVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMF 678
V L GG++IPVT+ENK ++ +F M+ + + +A SGF +I MF
Sbjct: 857 LVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEW-IRMF 915
Query: 679 KSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEIL-PQLSHEQQRQFLH 737
+ E++RLI G ++D E L+ T Y GGFH V+ WLW+IL + +++ FL
Sbjct: 916 STPELQRLISGD-NAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLK 974
Query: 738 FVTGSDRVPVTGLATL--PFKV----------TRTTSGS-------------HDQLPTAH 772
FVT R P+ G A L PF + T T GS +LPT+
Sbjct: 975 FVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSS 1034
Query: 773 TCFNELCLYEYESRDTLLLRLVTALEMYEGY 803
TCFN L L Y + L +L A+ M G+
Sbjct: 1035 TCFNLLKLPNYSKKSVLREKLRYAISMNTGF 1065
>Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1083
Score = 145 bits (365), Expect = 3e-34
Identities = 117/431 (27%), Positives = 196/431 (45%), Gaps = 31/431 (7%)
Query: 384 LDDLSMTQLHETHYTALCQYPFLMSLGVKIAIME-FETGKMMEHNAEQAFLKALDSRKLY 442
L+ ++ E L + PF++ ++ I + E + FL ++
Sbjct: 670 LESPPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGIN----- 724
Query: 443 DVHFRIKVRRSHVTQDSLTSIQ-RHPHDLKKSLRVEFSN-----EPGIDAGGLKKEWFLL 496
+ +RR+++ +D+ + + DLKK +RV N E GID GG+ +E+
Sbjct: 725 -----VTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNE 779
Query: 497 LTRELFHPNHGLFQYVEESRLSWFAYGNTGLK-LHGENNNELYYLFGVVLGLAIYNSTIL 555
L + F+PN G F+ E L Y N + L G++ YY +LG A+Y + ++
Sbjct: 780 LLKSGFNPNQGFFKTTNEGLL----YPNPAAQMLVGDSFARHYYFLARMLGKALYENMLV 835
Query: 556 DLHFARAMYKKLCNER--ITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYD 613
+L FA KL + L PE +NL + SY + D ++ GL+F D
Sbjct: 836 ELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYED-DVEEL-GLNFTVVNND 893
Query: 614 VASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGL 673
+ V L GG+ IPVTS N+ ++ ++ +N + AF+ G V+
Sbjct: 894 LGEAQVVE--LKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEW 951
Query: 674 AFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQR 733
MF E++ LI G+ + + E L++ T Y GG+ PV++ W ++ + E++R
Sbjct: 952 -LRMFDQQEIQVLISGA-QVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKR 1009
Query: 734 QFLHFVTGSDRVPVTGLATL-PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLR 792
+ L FVT R P+ G L P ++LPTA TC N L L E+ L +
Sbjct: 1010 KLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSK 1069
Query: 793 LVTALEMYEGY 803
L+ A+E G+
Sbjct: 1070 LLYAIECAAGF 1080
>CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 810
Score = 141 bits (355), Expect = 5e-33
Identities = 116/399 (29%), Positives = 172/399 (43%), Gaps = 82/399 (20%)
Query: 450 VRRSHVTQDSLTSIQ-RHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGL 508
V R + +DS I + +DL+ L +EF E G+D GG+ +EWF LL+ ++F+P +GL
Sbjct: 441 VHRDTLFEDSYRHIMDKKDYDLRNKLWIEFFGETGLDYGGVTREWFFLLSHQIFNPYYGL 500
Query: 509 FQYVEESRLSWFAYGNTGLKL-------------------------------------HG 531
F+Y S +F LKL H
Sbjct: 501 FEY---SATPFFWAIKCFLKLYKPTKKWRNFQILVINSNKQFLKKKNYRDNYTLQINPHS 557
Query: 532 ENNN----ELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARN 587
E N ++ G ++G+AIY+ +LD F R YK + ++IT D E + E +
Sbjct: 558 EACNPEHLSYFHFIGRIIGMAIYHGKLLDAFFIRPFYKMMLGKKITLFDMESVDNEYYNS 617
Query: 588 LKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVN 647
L + D F L D G L G ++PVT +NK E++E V
Sbjct: 618 LIYVKDNDPADLELTFSLD------DSIFGETQNIELIPNGANVPVTEDNKEEYIEAVV- 670
Query: 648 FYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQ 707
S R +F + E+E L+CG Q +D + +A T Y+
Sbjct: 671 --------------PSNLLR---------LFDANELELLMCGL--QKIDVKDWKANTIYK 705
Query: 708 GGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL-----PFKVTRTTS 762
GG+ + VV W+ + +E + + L FV+G+ RVP+ G L K T
Sbjct: 706 GGYGPSSQVVHNFWKCILSFDNEMRARVLQFVSGTSRVPMNGFRELYGSNGLQKFTIERW 765
Query: 763 GSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYE 801
GS D LP AHTCFN L L Y + L +L+TA+E E
Sbjct: 766 GSADMLPRAHTCFNRLDLPPYTTFKELKSKLLTAIENSE 804
>At3g53090 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1142
Score = 139 bits (351), Expect = 1e-32
Identities = 106/373 (28%), Positives = 166/373 (44%), Gaps = 26/373 (6%)
Query: 448 IKVRRSHVTQDSLTSIQRHPHDLKKSLRVEFSNEPGI-----DAGGLKKEWFLLLTRELF 502
I VRR HV +D + LK S+ V F NE G+ D GGL KE+ +T+ F
Sbjct: 776 IVVRRGHVVEDGFQQLNSIGSRLKSSIHVSFVNESGLPEAGLDYGGLSKEFLTDITKAAF 835
Query: 503 HPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARA 562
+GLF S + H EN ++ G ++G A+Y +LD F+
Sbjct: 836 ATEYGLFSQTPTSDRLLVPSPSAR---HLENGIQMIEFLGRIVGKALYEGILLDYSFSHV 892
Query: 563 MYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTK 622
+KL ++ L PE RNL + Y D+ L + T + G
Sbjct: 893 FIQKLLGRYSFIDELSGLDPELYRNLMYVKHYD----GDLKELCLDFTVTEEFCGKMSII 948
Query: 623 PLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCE 682
L GG+ VT+ENK +++ ++ +N + +AF G T +I +F + E
Sbjct: 949 ELKPGGKDTSVTNENKMQYIHAMADYKLNRQIVPFSNAFYRGLTDLISPAW-LKLFNAHE 1007
Query: 683 VERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGS 742
+L+ G D+D + LR TKY GG+ + + ++ WE++ ++ L FVT
Sbjct: 1008 FNQLLSGG-NHDIDVDDLRRNTKYTGGYSDSSRTIKIFWEVMKGFEPSERCLLLKFVTSC 1066
Query: 743 DRVPVTGLATLP-----FKVTRTTS-----GSHD--QLPTAHTCFNELCLYEYESRDTLL 790
R P+ G L KV+ TS G D +LP+A TC+N L L Y+ T+
Sbjct: 1067 SRAPLLGFKYLQPTFIIHKVSCDTSLWAAIGGQDVERLPSASTCYNTLKLPTYKRASTMR 1126
Query: 791 LRLVTALEMYEGY 803
+L+ A+ G+
Sbjct: 1127 EKLLYAITSNAGF 1139
>Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase
Length = 218
Score = 135 bits (339), Expect = 3e-31
Identities = 80/228 (35%), Positives = 128/228 (56%), Gaps = 14/228 (6%)
Query: 582 PETARNLKKMLSYS---ELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENK 638
PE A L ++LS+ E DF F + + GI + L GG+ I VT++N+
Sbjct: 2 PELAHGLSELLSHEGNVEEDFYSTFQV------FQEEFGIIKSYNLKPGGDKISVTNQNR 55
Query: 639 TEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFE 698
E+V+ + +F +N+ + F+AF GF V A + + EVE L+CGS D+D
Sbjct: 56 KEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASN-ALMLLRPEEVEILVCGS--PDLDMH 112
Query: 699 QLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVT 758
L+ T+Y G + +++ W+++ + Q++ LHF TGSDRVPV G+A L FK++
Sbjct: 113 ALQRSTQYDG-YAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKIS 171
Query: 759 RTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYGFK 806
+ + S + LP AHTCFN+LCL Y+S+ L +L+ + EG+G +
Sbjct: 172 KNET-STNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 218
>7295004 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1078
Score = 132 bits (331), Expect = 3e-30
Identities = 110/390 (28%), Positives = 177/390 (45%), Gaps = 42/390 (10%)
Query: 448 IKVRRSHVTQDSLTSIQRHPHD-LKKSLRVEFSN-----EPGIDAGGLKKEWFLLLTREL 501
I + R + +D + P LK +RV F N E GID G+ KE+ +++
Sbjct: 694 IVIHRDRIVEDGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKV 753
Query: 502 FHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFAR 561
F P+ LF+ + RL + + +N+ EL+ G +LG A+Y ++D+ FA
Sbjct: 754 FDPSLNLFKTTSDQRLY-----PSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFAS 808
Query: 562 AMYKKLCNE--RITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGIN 619
+L + + + +EL P L + L++ + D+ L+ + G
Sbjct: 809 FFLSQLLGQTQQALYSCMDEL-PSLDNELYRSLTFIKHYKQDVSDLNLTFSVDQDVMGKI 867
Query: 620 VTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFK 679
VT L GG++ V NK ++ F+MN + AF GF ++ +F
Sbjct: 868 VTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEW-LSLFS 926
Query: 680 SCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQ-LSHEQQRQFLHF 738
E++RLI G +D + L+ T Y GGFH+ VV WLW+IL + + E+++ FL F
Sbjct: 927 PPELQRLISGDTSP-LDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKF 985
Query: 739 VTGSDRVPVTGLATL--PFKV----------TRTTSGS-------------HDQLPTAHT 773
VT + P+ G A L PF + T T GS ++LPT+ T
Sbjct: 986 VTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSST 1045
Query: 774 CFNELCLYEYESRDTLLLRLVTALEMYEGY 803
CFN L L Y+ + TL +L A+ G+
Sbjct: 1046 CFNLLKLPNYQKKSTLRDKLRYAVSSNTGF 1075
>Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 823
Score = 131 bits (330), Expect = 4e-30
Identities = 101/382 (26%), Positives = 177/382 (45%), Gaps = 24/382 (6%)
Query: 439 RKLYDVHFR-------IKVRRSHVTQDSLTSIQRHP-HDLKKSLRVEFSNEPGIDAGGLK 490
R+L VH + +KV R + + SL + + D K+ V F +E +D GG +
Sbjct: 448 RELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPR 507
Query: 491 KEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIY 550
+EWF L+ + LF + LF ++ + + N H ++Y G ++G +Y
Sbjct: 508 REWFELICKALFDTTNQLFTRFSDNNQA-LVHPNPNRPAH--LRLKMYEFAGRLVGKCLY 564
Query: 551 NSTI-------LDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIF 603
S++ + F R+ ++ R+ ++ +E PE ++ K+ D S++
Sbjct: 565 ESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKS--KVCFILNNDMSEM- 621
Query: 604 GLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQS 663
L F Y+ + ++ L GG PVT+ NK ++ + + V F
Sbjct: 622 ELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLK 681
Query: 664 GFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEI 723
G ++ + L +F E+E L+CG+ + + + AV G +H + V+ W W +
Sbjct: 682 GLNELVPENL-LAIFDENELELLMCGTGDISVSDFKAHAVV-VGGSWHFREKVMRWFWTV 739
Query: 724 LPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEY 783
+ L+ E+ + L F TGS ++P G A L + +H LPTAHTCFN+LCL Y
Sbjct: 740 VSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTY 799
Query: 784 ESRDTLLLRLVTAL-EMYEGYG 804
+S + + L A+ E EG+G
Sbjct: 800 DSYEEVHRMLQLAISEGCEGFG 821
>7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 971
Score = 130 bits (328), Expect = 6e-30
Identities = 100/374 (26%), Positives = 170/374 (44%), Gaps = 18/374 (4%)
Query: 442 YDVHFRIKVRRSHVTQDSLTSIQRHP-HDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRE 500
Y +KV+R + + S+ +++ D + V F E GID GGL++EWF L+
Sbjct: 603 YHEKMALKVQREKILESSMKAVKGFSVSDWCGNFEVTFQGEQGIDWGGLRREWFELVCSA 662
Query: 501 LFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTI------ 554
LF GLF + + + N H + + + G ++G ++ S +
Sbjct: 663 LFDARGGLFCTFHDKHQA-LVHPNPTRPAHLKLKH--FEFAGKMVGKCLFESALGGTYRQ 719
Query: 555 -LDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYD 613
+ F+R+ +L R+ ++ +E+ P+ + K + ++LD +D L F YD
Sbjct: 720 LVRARFSRSFLAQLIGLRVHYKYFEQDDPDLYLSKIKYILDTDLDATDTLELYFVEEMYD 779
Query: 614 VASG-INVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDG 672
+SG ++ T L G VT+ K ++++ + V +F G +I D
Sbjct: 780 SSSGQLSKTIELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDN 839
Query: 673 LAFPMFKSCEVERLICGSIEQDM-DFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQ 731
L +F E+E L+CG+ E + DF+ F V+ W W + S +
Sbjct: 840 L-LSIFDENELELLMCGTGEYSISDFKAHHIANGNSAEFRR---VLAWFWAGVSNFSQTE 895
Query: 732 QRQFLHFVTGSDRVPVTGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLLL 791
+ L F TG ++P G L + T + + LPTAHTCFN+LCL +YES +
Sbjct: 896 MARLLQFTTGCSQLPPGGFQELNPQFQITAAPTFGNLPTAHTCFNQLCLPDYESYEQFEK 955
Query: 792 RLVTAL-EMYEGYG 804
L+ A+ E EG+G
Sbjct: 956 SLLLAISEGSEGFG 969
>Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 308
Score = 128 bits (321), Expect = 4e-29
Identities = 94/320 (29%), Positives = 162/320 (50%), Gaps = 24/320 (7%)
Query: 495 LLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLF-GVVLGLAIYNST 553
++++RE+F+P + LF+ R+++ ++ H N+ Y+ F G ++ A+Y++
Sbjct: 1 MIISREMFNPMYALFRTSPGDRVTYTINPSS----HCNPNHLSYFKFVGRIVAKAVYDNR 56
Query: 554 ILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSDI-FGLSFETTYY 612
+L+ +F R+ YK + + + + D E E + ++ E D S + + L+F T
Sbjct: 57 LLECYFTRSFYKHILGKSVRYTDMES---EDYHFYQGLVYLLENDVSTLGYDLTFSTEVQ 113
Query: 613 DVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDG 672
+ G+ + L G +I VT ENK E+V M + +AF GF +I
Sbjct: 114 EF--GVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR 171
Query: 673 LAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQ 732
L +F E+E LI G +D + L++ T+Y + + + ++W W L +
Sbjct: 172 L-ISIFTEQELELLISGL--PTIDIDDLKSNTEYHK-YQSNSIQIQWFWRALRSFDQADR 227
Query: 733 RQFLHFVTGSDRVPVTGLATL-------PFKVTRTTSGSHDQLPTAHTCFNELCLYEYES 785
+FL FVTG+ +VP+ G A L F++ R S D+LP+AHTCFN+L L YES
Sbjct: 228 AKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHR-DDRSTDRLPSAHTCFNQLDLPAYES 286
Query: 786 RDTLLLRLVTAL-EMYEGYG 804
+ L L+ A+ E EG+G
Sbjct: 287 FEKLRHMLLLAIQECSEGFG 306
>CE19147 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1066
Score = 127 bits (319), Expect = 7e-29
Identities = 109/394 (27%), Positives = 178/394 (44%), Gaps = 49/394 (12%)
Query: 448 IKVRRSHVTQDSLTSIQRHPHD-LKKSLRVEFSNEPGIDAGGLK-----KEWFLLLTREL 501
I V+R+ + +D + + LK ++RV+F NE G+D G+ KE+ L +++
Sbjct: 685 ITVQRNRIIEDGFNHLSKLTIPALKSTIRVKFVNEQGLDEAGIDQDGVFKEFLELTLKKV 744
Query: 502 FHPNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFAR 561
F P LF L Y + LH +++ L+ G +LG A+Y ++D+ A
Sbjct: 745 FDPQLNLFSTTSTGVL----YPSPTSSLH-DDHLALFTFVGRMLGKAVYEGIVVDVQLAP 799
Query: 562 AMYKKLCNER--ITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGIN 619
+ + F++ +L PE R+L + Y ++ LS + + G
Sbjct: 800 VLLAAVLGSHRLCAFDELSQLDPELYRSLTFVKRYE----GEMADLSLTFSVDEDFMGKI 855
Query: 620 VTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFK 679
T L G +I VT+ENK ++V R + + AF +G ++ +F
Sbjct: 856 STVDLVPSGRTISVTNENKIDYVHRMAHHRVFRRTQEQCKAFVTGMQSIL-QPTWLSLFA 914
Query: 680 SCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILP-QLSHEQQRQFLHF 738
+++ LI G + D+D L+ +Y GGFH +++WLW+IL + + E+++ FL F
Sbjct: 915 PNDLQCLISG-VNSDIDLADLKRNVQYFGGFHGNHRLIKWLWDILENKFTSEERKLFLKF 973
Query: 739 VTGSDRVPVTGLATL--PFKVTRTTSGSHDQ------------------------LPTAH 772
VT R PV G + L PF + R S DQ LPTA
Sbjct: 974 VTSCSRPPVLGFSYLEPPFSI-RCVEVSDDQDQGDTLGSVVRGFLALRKGTAATRLPTAS 1032
Query: 773 TCFNELCLYEYESRDTLLLRLVTALEMYEGYGFK 806
TCFN L L Y + LL +L A+ + G GF+
Sbjct: 1033 TCFNLLKLPNYNKKSLLLEKLRYAI--HAGTGFE 1064
>Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 650
Score = 116 bits (291), Expect = 1e-25
Identities = 113/429 (26%), Positives = 192/429 (44%), Gaps = 65/429 (15%)
Query: 422 KMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLT----SIQRHPHDLKKSLRVE 477
++++ N E + DSR V R+ ++ V ++ L S+ + + L ++
Sbjct: 222 RLLDTNPEINQSDSQDSR----VAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQ 277
Query: 478 FSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQ-----------------YVEESR-LSW 519
+ NE G G E++ L+++EL + GL++ Y++ + L
Sbjct: 278 YENEVGTGLGPTL-EFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFA 336
Query: 520 FAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNER--ITFEDY 577
+G T H + G ++ AI + ++DL YK + + +T D
Sbjct: 337 LPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDL 396
Query: 578 EELYPETARNL---------KKMLSYSELDFSDIFGLSFETTYYDVAS----GINVTKP- 623
++ P AR++ KK L + + + ET + S G++ T P
Sbjct: 397 FDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPG 456
Query: 624 -----LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPM- 677
L GG+ IPVT N E++ + + +NEGVS F +F+ GF V FP+
Sbjct: 457 FPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESV------FPLS 510
Query: 678 ----FKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQR 733
F E+++L+CGS D + L + G+ + + V++L+EIL +EQQR
Sbjct: 511 HLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQR 570
Query: 734 QFLHFVTGSDRVPVTGLATL--PFKVTR----TTSGSHDQLPTAHTCFNELCLYEYESRD 787
FL FVTGS R+PV G +L P + R +T D LP+ TC N L L +Y S +
Sbjct: 571 LFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIE 630
Query: 788 TLLLRLVTA 796
+ +L+ A
Sbjct: 631 IMREKLLIA 639
>YGL141w [O] KOG0942 E3 ubiquitin protein ligase
Length = 910
Score = 115 bits (288), Expect = 3e-25
Identities = 100/359 (27%), Positives = 163/359 (44%), Gaps = 26/359 (7%)
Query: 450 VRRSHVTQDSLTSIQRHPHDLKKSLRV----EFSNEPGIDAGGLKKEWFLLLTRELFH-P 504
+ R +V +D+ + K SL V EF E GID GG+ KE+ ++ E F P
Sbjct: 558 ISRDNVLEDAFNAFNSIGERFKASLDVTFINEFGEEAGIDGGGITKEFLTTVSDEGFKDP 617
Query: 505 NHGLFQYVEESRL-SWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAM 563
H LF+ + L Y T LK + G V+G +Y ++D+ FA
Sbjct: 618 KHELFRTNDRYELYPSVVYDATKLKY--------IWFLGKVVGKCLYEHVLIDVSFADFF 669
Query: 564 YKKLCNER----ITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGIN 619
KKL N +F D NL K+L+ + + + L+FE + ++ +
Sbjct: 670 LKKLLNYSNGFLSSFSDLGSYDSVLYNNLIKLLNMTTDEIKSL-DLTFEIDEPESSAKV- 727
Query: 620 VTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFK 679
L G VT +N +V + ++ +N+ SAF G + +I MF
Sbjct: 728 --VDLIPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHW-MEMFN 784
Query: 680 SCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFV 739
S E++ LI G ++D + L++ T+Y GG+ + + WE+L + E++ FL FV
Sbjct: 785 SIELQMLISGE-RDNIDLDDLKSNTEY-GGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFV 842
Query: 740 TGSDRVPVTGLATLPFKVTRTTSGSHD-QLPTAHTCFNELCLYEYESRDTLLLRLVTAL 797
T + P+ G L K +G+ +LPTA TC N L L +Y ++ L +L+ A+
Sbjct: 843 TSVPQAPLQGFKALDPKFGIRNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAI 901
>At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 873
Score = 110 bits (274), Expect = 1e-23
Identities = 95/384 (24%), Positives = 165/384 (42%), Gaps = 10/384 (2%)
Query: 415 IMEFETGKMMEHNAEQAFLKALDSRKLYDVHFRIKVRRSHVTQDSLTSIQ-RHPHDLKKS 473
I E++ E A L D ++ ++ + + RS++ +S I P L
Sbjct: 480 IFEYKEATNFEARRHLAMLLFPDVKEDFEEMHEMLIDRSNLLSESFEYIVGASPEALHGG 539
Query: 474 LRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQYVEESRLSWFAYGNTGLKLHGEN 533
L +EF NE G L+ EWF L+ +E+F+P + LF S + +
Sbjct: 540 LFMEFKNEEATGPGVLR-EWFYLVCQEIFNPKNTLFL---RSADDFRRFSPNPASKVDPL 595
Query: 534 NNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLS 593
+ + + G V+ LA+ + + + F R + +L +I+ ED ++ + K++L
Sbjct: 596 HPDFFEFTGRVIALALMHKVQVGVLFDRVFFLQLAGLKISLEDIKDTDRIMYNSCKQILE 655
Query: 594 YSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEG 653
F GL G T LC G+ V S+N+ ++V+ +
Sbjct: 656 MDPEFFDSNAGLGLTFVLETEELGKRDTIELCPDGKLKAVNSKNRKQYVDLLIERRFATP 715
Query: 654 VSSSFSAFQSGFTRVIGDGLA-FPMFKSCEVERL--ICGSIEQDMDFEQLRAVTKYQGGF 710
+ F GFT ++ + FK +E L + E + + +A T+Y G F
Sbjct: 716 ILEQVKQFSRGFTDMLSHSVPPRSFFKRLYLEDLDGMLRGGENPISIDDWKAHTEYNG-F 774
Query: 711 HNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKV-TRTTSGSHDQLP 769
++W W+IL +++ E+QR L F T + VPV G L K+ ++D+LP
Sbjct: 775 KETDRQIDWFWKILKKMTEEEQRSILFFWTSNKFVPVEGFRGLSSKLYIYRLYEANDRLP 834
Query: 770 TAHTCFNELCLYEYESRDTLLLRL 793
+HTCF LC+ Y + + RL
Sbjct: 835 LSHTCFYRLCIPRYPTITLMEQRL 858
>Hs4557026 [S] KOG1426 FOG: RCC1 domain
Length = 4861
Score = 108 bits (270), Expect = 3e-23
Identities = 79/266 (29%), Positives = 141/266 (52%), Gaps = 16/266 (6%)
Query: 538 YYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEE---LYPETARNLKKM--L 592
+ G+++G+AI LDLH A ++K+LC +T ED EE LY +T ++ +
Sbjct: 4579 FKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDS 4638
Query: 593 SYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNE 652
+E F ++ L ++ A G V P+ GG SIP+T N+ E+VER + + ++E
Sbjct: 4639 GITEESFHEMIPL--DSFVGQSADGKMV--PIIPGGNSIPLTFSNRKEYVERAIEYRLHE 4694
Query: 653 GVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHN 712
+ +A + G + ++ L + + ++E+++CG E + E L+ V +Y+
Sbjct: 4695 -MDRQVAAVREGMSWIVPVPL-LSLLTAKQLEQMVCGMPE--ISVEVLKKVVRYR-EVDE 4749
Query: 713 QTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPV-TGLATLPFKVTRTTSGSHDQLPTA 771
Q +V+W W L + S+E++ F+ FV+G R+P T + F++ + +D LPT+
Sbjct: 4750 QHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMK-VDRPYDSLPTS 4808
Query: 772 HTCFNELCLYEYESRDTLLLRLVTAL 797
TCF +L L Y S+ + RL A+
Sbjct: 4809 QTCFFQLRLPPYSSQLVMAERLRYAI 4834
>At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 628
Score = 107 bits (266), Expect = 9e-23
Identities = 97/364 (26%), Positives = 163/364 (44%), Gaps = 35/364 (9%)
Query: 471 KKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGLFQY---------VEESRLSWFA 521
K + VE+S E G G E++ L++R +P+ G+++ VE S + +
Sbjct: 263 KVVIEVEYSEEVGTGLGPTL-EFYTLVSRAFQNPDLGMWRNDCSFIVGKPVEHSGVLASS 321
Query: 522 YGNTGLKLHGENNN----ELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDY 577
G G + + + L G V+ A+ + +LDL ++A YK + + ++ D
Sbjct: 322 SGLFPRPWSGTSTTSDVLQKFVLLGTVVAKALQDGRVLDLPLSKAFYKLILGQELSSFDI 381
Query: 578 EELYPETARNL---------KKMLSYSELDFS------DIFGLSFETTYYDVASGINVTK 622
+ PE + L KK+ + + D G E + A
Sbjct: 382 HFVDPELCKTLVELQALVRRKKLFAEAHGDSGAAKCDLSFHGTKIEDLCLEFALPGYTDY 441
Query: 623 PLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCE 682
L + V +N E+++ VN + G+ AF+SGF +V +F E
Sbjct: 442 DLAPYSANDMVNLDNLEEYIKGIVNATVCNGIQKQVEAFRSGFNQVFSIE-HLRIFNEEE 500
Query: 683 VERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGS 742
+E ++CG + E L + K+ G+ + +P VE+L +IL + EQQR FL FVTGS
Sbjct: 501 LETMLCGECDLFSMNEVLDHI-KFDHGYTSSSPPVEYLLQILHEFDREQQRAFLQFVTGS 559
Query: 743 DRVPVTGLATLPFKVT----RTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALE 798
R+P GLA+L K+T + S LP+ TC N L L Y S++ + +L+ A+
Sbjct: 560 PRLPHGGLASLSPKLTIVRKHGSDSSDTDLPSVMTCANYLKLPPYSSKEKMKEKLIYAIT 619
Query: 799 MYEG 802
+G
Sbjct: 620 EGQG 623
>CE15744 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1001
Score = 106 bits (265), Expect = 1e-22
Identities = 96/373 (25%), Positives = 166/373 (43%), Gaps = 26/373 (6%)
Query: 448 IKVRRSHVTQDSLTSIQRHP-----HDLKKSLRVEF-----SNEPGIDAGGLKKEWFLLL 497
+ VRR V D+ + +DLK +RV+ NE GID GG+ +E+ L
Sbjct: 635 VTVRRDQVYMDAFETFAPKMQGDKVNDLKSMVRVKMVNWAGMNESGIDGGGIFREFLSEL 694
Query: 498 TRELFHPNHGLFQYVEESRLSWFAYGN-TGLKLHGENNNELYYLFGVVLGLAIYNSTILD 556
+ F+ G F + E L Y N T L G + + G ++G IY + +
Sbjct: 695 LKTAFNVERGFFTFTESKLL----YPNPTAPFLLGVDCLAHFQFIGRMIGKLIYERQLQE 750
Query: 557 LHFARAMYKKLC----NERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYY 612
+ FA ++ N+ + + + P ++LK + + + ++ L F
Sbjct: 751 VRFAEFFIAQIFETDKNKDVDLQHMKSFDPIIFKHLKALQKMNNRELDEL-QLDFSVVTS 809
Query: 613 DVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDG 672
D+ NV L G VT EN E+V +VN+++ + ++S A + G + +I
Sbjct: 810 DMGLVRNVN--LKPNGSKFRVTVENVHEYVRLYVNYHLKQRIASMVDAVRKGISEIISIE 867
Query: 673 LAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQT-PVVEWLWEILPQLSHEQ 731
MF E++ +I G E+ ++LR + + Q E W+++ +LS++
Sbjct: 868 W-MRMFAPHELQIMIAG-YEEVFTAKELRKFCELRFAAGTQDINYEEMFWDVIDKLSNDD 925
Query: 732 QRQFLHFVTGSDRVPVTGLATL-PFKVTRTTSGSHDQLPTAHTCFNELCLYEYESRDTLL 790
++ L FVTG R PV G ++ P S D+LPT+ TC N L + +Y +R L
Sbjct: 926 KKALLKFVTGCSRAPVDGFKSIQPRMGVLVIPSSDDELPTSATCMNMLRIPKYSNRTKLE 985
Query: 791 LRLVTALEMYEGY 803
+L A+ G+
Sbjct: 986 EKLRYAINSGAGF 998
>CE17508 [R] KOG4276 Predicted hormone receptor interactor
Length = 2761
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/431 (23%), Positives = 176/431 (40%), Gaps = 86/431 (19%)
Query: 445 HFRIKVRRSHVTQ-DSLTSIQRHPHDLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFH 503
H R+KV R+ T D + + D K L +E++NE G G E++ L+ EL
Sbjct: 2331 HERVKVTRAEETLLDQAIRLMKFHADRKAVLEIEYTNEEGTGLGPTL-EFYALVAAELQR 2389
Query: 504 PNHGLFQYVEESRLSWFAYGNTGLKLHGENNNELYY------------------------ 539
+ L+ ++ + + + L GE + Y
Sbjct: 2390 KSLALWVCDDDDTHASKSGEEREVDL-GEGKKPIGYYVRRVGGLFPAPLPPGTDETKRAA 2448
Query: 540 ----LFGVVLGLAIYNSTILDLHFARAMYKKLCNERI-------------TFEDYEELYP 582
+ GV L + + ++DL +R K L + +I + +D+EE+ P
Sbjct: 2449 DMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDDFEEVNP 2508
Query: 583 ETARNLKKMLSYSE----------LDFSDIFGLSFETTYY---------DVASGINVTKP 623
LK++ + ++ +D + E + D+A V P
Sbjct: 2509 VKGSFLKELRALAQRKRLIENDTSIDSNSKRRKIAELKLHIKGSTCRVEDLALNFTVNPP 2568
Query: 624 ----------LCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGL 673
L DGG I VT +N ++VE+ FY+N G++ AF+ GF RV
Sbjct: 2569 SKVFQYAEMELVDGGSDIDVTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRV----- 2623
Query: 674 AFPM-----FKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLS 728
FP+ + EV+RL+ G + + + T+ + G+ ++P +++ L+
Sbjct: 2624 -FPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALT 2682
Query: 729 HEQQRQFLHFVTGSDRVPVTGLATLPFKVT--RTTSGSHDQLPTAHTCFNELCLYEYESR 786
++++ FL F TG +P GLA L ++T R P+ +TC + L L EY S
Sbjct: 2683 AQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSS 2742
Query: 787 DTLLLRLVTAL 797
L RL+TA+
Sbjct: 2743 AILRERLLTAI 2753
>SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase
Length = 400
Score = 89.4 bits (220), Expect = 2e-17
Identities = 73/288 (25%), Positives = 133/288 (45%), Gaps = 16/288 (5%)
Query: 526 GLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEEL---YP 582
G E L++ G + +IY+S I+ + F + + N +T ++
Sbjct: 115 GSSPENERKISLFFALGQFVARSIYDSRIISIQFNPLFFAR--NIPLTISSVAKVDKGLA 172
Query: 583 ETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFV 642
+ R L+K++ ++ + E + D + L G S PVT+ N ++++
Sbjct: 173 NSLRYLEKLIPGKNPTNAET-DIKLEDLHLDFTLPGFPSIELIPDGASTPVTTFNVSDYL 231
Query: 643 ERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRA 702
+++ + +GV AFQ+GF+ V + + E+ L G++++D + L
Sbjct: 232 NYVIDYTVGKGVQQQLEAFQNGFSSVF-PYTSLQVLTEHELVTLF-GTVDEDWSYATLMK 289
Query: 703 VTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATL--PFKVTRT 760
G+ ++P ++ L ++ Q++ ++QR FL F+TGS ++P+ G A L P V R
Sbjct: 290 SIVADHGYTMESPTIQRLLTLMSQMNFQEQRDFLQFITGSRKLPIGGFAGLNPPLTVVRR 349
Query: 761 TSG----SHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
+ D LP+ TC N L L EY S + L RL A+ EG G
Sbjct: 350 LNEPPYVPDDYLPSVMTCVNYLKLPEYSSSEVLGSRLSKAI--LEGQG 395
>At4g38600 [O] KOG0170 E3 ubiquitin protein ligase
Length = 757
Score = 82.4 bits (202), Expect = 3e-15
Identities = 76/298 (25%), Positives = 134/298 (44%), Gaps = 38/298 (12%)
Query: 536 ELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKM-LSY 594
E + L G V+ A+ + +LD+ + A YK + + + D E + L+++ +
Sbjct: 462 EYFRLLGRVMAKALQDGRLLDVPLSTAFYKLILGQELDLHDIVLFDAELGKTLQELRVVV 521
Query: 595 SELDFSDIFGLSFETTYYDVAS--------GINVTKP------LCDGGESIPVTSENKTE 640
+ + + G +T D+ + T P L G E + +T N E
Sbjct: 522 ARKHYLEGVGGDNSSTISDLCLRGCRIEDLSLEFTLPGYPEYILRSGDEIVDIT--NLEE 579
Query: 641 FVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQL 700
++ V+ + GV+ AF+SGF +V D + +F E++ L+CG E + E L
Sbjct: 580 YISLVVDATVKRGVTRQIEAFRSGFNQVF-DITSLQIFTPSELDYLLCGRREL-WEVETL 637
Query: 701 RAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVT-- 758
K+ G++ ++P + + S +QQR F FVTG+ R+P GLA L K+T
Sbjct: 638 AEHIKFDHGYNAKSPAII---NVCYPSSSDQQRAFCQFVTGAPRLPPGGLAVLNPKLTIV 694
Query: 759 ---RTTSG-----------SHDQLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEG 802
+TS + D LP+ TC N L L Y +++ + +L+ A+ +G
Sbjct: 695 RKHSSTSSAAANGAGASETADDDLPSVMTCANYLKLPPYSTKEIMYKKLLYAINEGQG 752
>Hs4758520 [S] KOG1426 FOG: RCC1 domain
Length = 4834
Score = 81.6 bits (200), Expect = 4e-15
Identities = 67/268 (25%), Positives = 123/268 (45%), Gaps = 15/268 (5%)
Query: 534 NNELYYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLS 593
++ ++ GV+LG+AI + L L+ A ++K+L +T D E+ + L +
Sbjct: 4529 HSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRD 4588
Query: 594 YSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEG 653
+E + +S T ASG ++ + +T +N+ E+V +N+ ++E
Sbjct: 4589 -NEATSEEFEAMSLPFTVPS-ASGQDIQL----SSKHTHITLDNRAEYVRLAINYRLHE- 4641
Query: 654 VSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQ 713
+A + G RV+ L +F E+E ++CGS D+ L++V Y+G
Sbjct: 4642 FDEQVAAVREGMARVVPVPL-LSLFTGYELETMVCGS--PDIPLHLLKSVATYKG-IEPS 4697
Query: 714 TPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGL----ATLPFKVTRTTSGSHDQLP 769
+++W WE++ S+ ++ FL FV G R+P T +V + LP
Sbjct: 4698 ASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLP 4757
Query: 770 TAHTCFNELCLYEYESRDTLLLRLVTAL 797
++TCF L L Y + L +L A+
Sbjct: 4758 ESYTCFFLLKLPRYSCKQVLEEKLKYAI 4785
>7297647 [R] KOG4276 Predicted hormone receptor interactor
Length = 2727
Score = 78.6 bits (192), Expect = 4e-14
Identities = 63/236 (26%), Positives = 105/236 (43%), Gaps = 20/236 (8%)
Query: 569 NERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKP-LCDG 627
++ I+ E EL E + L S D + F TY +S T+ L
Sbjct: 2495 DDTISAEKKHELINELKLQTQNGLEVSLEDLALTF------TYLPSSSIYGYTQAELLPN 2548
Query: 628 GESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPM-----FKSCE 682
G S+ VT +N + E +NF + +G++ AF GF V FP+ F E
Sbjct: 2549 GSSVNVTIDNLEAYCELLMNFILQDGIAQQMKAFSDGFNEV------FPLKKLAAFTPSE 2602
Query: 683 VERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGS 742
+ICG E + + T+ + G++ +P + +L +S ++++ FL F TG
Sbjct: 2603 ARMMICGEQFPHWSREDIISYTEPKLGYNKDSPGFQRFVNVLLSMSGDERKAFLQFTTGC 2662
Query: 743 DRVPVTGLATLPFKVT--RTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+P GLA L ++T R P+ +TC + L L +Y + + + RL+TA
Sbjct: 2663 SSLPPGGLANLHPRLTVVRKVDAGVGSYPSVNTCVHYLKLPDYPTEEIMKERLLTA 2718
>Hs15300020 [R] KOG4276 Predicted hormone receptor interactor
Length = 1592
Score = 77.0 bits (188), Expect = 1e-13
Identities = 51/176 (28%), Positives = 85/176 (47%), Gaps = 13/176 (7%)
Query: 628 GESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQSGFTRVIGDGLAFPM-----FKSCE 682
GE +T +N E+V+ +F M+ G+ AF+ GF +V FPM F E
Sbjct: 1414 GEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKV------FPMEKLSSFSHEE 1467
Query: 683 VERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGS 742
V+ ++CG+ E + T+ + G+ +P +L +S ++++ FL F TG
Sbjct: 1468 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 1527
Query: 743 DRVPVTGLATLPFKVT--RTTSGSHDQLPTAHTCFNELCLYEYESRDTLLLRLVTA 796
+P GLA L ++T R + P+ +TC + L L EY S + + RL+ A
Sbjct: 1528 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAA 1583
>YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 470
Score = 74.3 bits (181), Expect = 7e-13
Identities = 69/283 (24%), Positives = 119/283 (41%), Gaps = 20/283 (7%)
Query: 536 ELYYLFGVVLGLAIYNSTILDLHFARAMYKKLC-----NERITFEDYEE---LYPETARN 587
EL+ G + ++ ++ ILD F++ ++ L N D E +
Sbjct: 189 ELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPL 248
Query: 588 LKKMLSYSELDFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVN 647
L K L Y + D L + + V ++ L GG + + S N E++ ++
Sbjct: 249 LAKSLKYIVANKDDNMTLESLSLTFTVPGNDDIE--LIPGGCNKSLNSSNVEEYIHGVID 306
Query: 648 FYMNEGVSSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQ 707
+ +G+ AF GF++V +F V+ I G +E+D L +
Sbjct: 307 QILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVD--IFGRVEEDWSMATLYTNLNAE 364
Query: 708 GGFHNQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTRTTSGSHD- 766
G+ + ++ I+ ++R FL F+TGS ++P+ G +L K T + D
Sbjct: 365 HGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDG 424
Query: 767 -----QLPTAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYG 804
LP+ TC N L L +Y S+D + RL A+E EG G
Sbjct: 425 LTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIE--EGAG 465
>Hs7661612 [O] KOG0941 E3 ubiquitin protein ligase
Length = 110
Score = 72.0 bits (175), Expect = 3e-12
Identities = 33/73 (45%), Positives = 52/73 (71%), Gaps = 1/73 (1%)
Query: 450 VRRSHVTQDSLTSIQRHPH-DLKKSLRVEFSNEPGIDAGGLKKEWFLLLTRELFHPNHGL 508
VRR ++ D++ +++ + D KK L+V F E +DAGG++KE+FLL+ REL P +G+
Sbjct: 30 VRRENIVGDAMEVLRKAKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGM 89
Query: 509 FQYVEESRLSWFA 521
F+Y E+SRL WF+
Sbjct: 90 FRYYEDSRLIWFS 102
>CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2944
Score = 69.7 bits (169), Expect = 2e-11
Identities = 58/271 (21%), Positives = 116/271 (42%), Gaps = 12/271 (4%)
Query: 538 YYLFGVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSEL 597
Y G ++G+ + I L F+R ++ + I + D P NL+ +
Sbjct: 2682 YRTVGRIMGICLSQGDIFPLRFSRHIFSYILKLPICWLDLGFYDPVLFNNLRALFKAHPS 2741
Query: 598 DFSDIFGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSS 657
+ F + ++ A G VT L G+ + V +N E+V ++ + +
Sbjct: 2742 ELDTDFSIVEQS-----ADGKAVTVNLKPNGDEVLVNKDNVIEYVYKYAERVLVGKRIIT 2796
Query: 658 FSAFQSGFTRVIGDGLAFPMFKSCEVERLICG--SIEQDMDFEQLRAVTKYQGGFHNQTP 715
F A + G VI + + F + ++ +ICG S+ + E + + +
Sbjct: 2797 FEAIREGILDVIPESMLFGLTPE-DLRLIICGIESVSISVLQENTGFLDESRASQETLNR 2855
Query: 716 VVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTRTTSGSHDQ-LPTAHTC 774
+W W+++ + +++++ + F TGS +P G P + D LPTA+TC
Sbjct: 2856 FKQWFWQVIESFTQQEKQELVFFWTGSPALPAAG--KWPTSASVMLRPQEDVFLPTANTC 2913
Query: 775 FNELCLYEYESRDTLLLRLVTALEMYEGYGF 805
+ L + Y S+ L +L+ A++ + +GF
Sbjct: 2914 ISRLYVPVYSSKRVLRTKLLLAIKA-KNFGF 2943
>Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2799
Score = 66.2 bits (160), Expect = 2e-10
Identities = 61/276 (22%), Positives = 115/276 (41%), Gaps = 22/276 (7%)
Query: 542 GVVLGLAIYNSTILDLHFARAMYKKLCNERITFEDYEELYPETARNLKKMLSYSELDFSD 601
G +LGL + + + + R + K L ++ + D+ P +L++++ S+ +D
Sbjct: 2533 GRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDAD 2592
Query: 602 IFGLSFETTYYDVASGINVTKP-------LCDGGESIPVTSENKTEFVERWVNFYMNEGV 654
+ D+A I++ K L G +IPVT +N E+V ++ M
Sbjct: 2593 AVFSAM-----DLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVA 2647
Query: 655 SSSFSAFQSGFTRVIGDGLAFPMFKSCEVERLI---CGSIEQDMDFEQLRAVTKYQGGFH 711
A + G V+ + + E RL+ CG + M +
Sbjct: 2648 EQPLHAMRKGLLDVLPKNSLEDL--TAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAE 2705
Query: 712 NQTPVVEWLWEILPQLSHEQQRQFLHFVTGSDRVPVT--GLATLPFKVTRTTSGSHDQLP 769
W W I+ ++S +++ ++F T S +P + G +P R H LP
Sbjct: 2706 KLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQH--LP 2763
Query: 770 TAHTCFNELCLYEYESRDTLLLRLVTALEMYEGYGF 805
TA+TC + L + Y S+ L +L+ A++ + +GF
Sbjct: 2764 TANTCISRLYVPLYSSKQILKQKLLLAIKT-KNFGF 2798
>Hs13375805 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 210
Score = 62.0 bits (149), Expect = 3e-09
Identities = 52/183 (28%), Positives = 86/183 (46%), Gaps = 10/183 (5%)
Query: 603 FGLSFETTYYDVASGINVTKPLCDGGESIPVTSENKTEFVERWVNFYMNEGVSSSFSAFQ 662
F E T+ V S V + L GG I V +++ F++ + E +A Q
Sbjct: 11 FKFGKELTFTTVLSDQQVVE-LIPGGAGIVVGYGDRSRFIQLVQKARLEES-KEQVAAMQ 68
Query: 663 SGFTRVIGDGLAFPMFKSCEVERLICGSIEQDMDFEQLRAVTKYQGGFHNQTPVVEWLWE 722
+G +V+ + + E+E+ +CG E +D LR +T+++ F V++ WE
Sbjct: 69 AGLLKVVPQAV-LDLLTWQELEKKVCGDPEVTVD--ALRKLTRFED-FEPSDSRVQYFWE 124
Query: 723 ILPQLSHEQQRQFLHFVTGSDRVPVTGLATLPFKVTRTTSGSHDQLPTAHTCFNELCLYE 782
L ++E + +FL FVTG R+P + P K+ T+ D LP + TC + L L
Sbjct: 125 ALNNFTNEDRSRFLRFVTGRSRLPAR-IYIYPDKLGYETT---DALPESSTCSSTLFLPH 180
Query: 783 YES 785
Y S
Sbjct: 181 YAS 183
>Hs17460052 [O] KOG0941 E3 ubiquitin protein ligase
Length = 103
Score = 56.2 bits (134), Expect = 2e-07
Identities = 34/107 (31%), Positives = 59/107 (54%), Gaps = 8/107 (7%)
Query: 508 LFQYVEESRLSWFAYGNTGLKLHGENNNELYYLFGVVLGLAIYNSTILDLHFARAMYKKL 567
+F Y E ++L WF + + G + L G+VLGLAIYN+ IL +HF +Y+K+
Sbjct: 1 MFTYDELTKLFWF--NPSSFQTEG-----WFTLIGIVLGLAIYNNCILGVHFPMVVYRKV 53
Query: 568 CNERITFEDYEELYPETARNLKKMLSYSELDFSDIFGLSFETTYYDV 614
++ TF + +P ++LK +L Y E + D ++F+ + D+
Sbjct: 54 MGKKGTFYHLGDCHPVLYQSLKDLLEY-EGNVEDDMMITFQVSQTDL 99
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.139 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,318,326
Number of Sequences: 60738
Number of extensions: 2328912
Number of successful extensions: 5495
Number of sequences better than 1.0e-05: 73
Number of HSP's better than 0.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 5168
Number of HSP's gapped (non-prelim): 96
length of query: 806
length of database: 30,389,216
effective HSP length: 115
effective length of query: 691
effective length of database: 23,404,346
effective search space: 16172403086
effective search space used: 16172403086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)