ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5923 good F KOG1377 Nucleotide transport and metabolism Uridine 5'- monophosphate synthase/orotate phosphoribosyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5923 2034995 2035795 267
(267 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YEL021w [F] KOG1377 Uridine 5'- monophosphate synthase/orotate p... 438 e-123
SPCC330.05c [F] KOG1377 Uridine 5'- monophosphate synthase/orota... 281 9e-76
Hs4507835 [F] KOG1377 Uridine 5'- monophosphate synthase/orotate... 238 7e-63
7300695 [F] KOG1377 Uridine 5'- monophosphate synthase/orotate p... 212 5e-55
CE00638 [F] KOG1377 Uridine 5'- monophosphate synthase/orotate p... 174 9e-44
>YEL021w [F] KOG1377 Uridine 5'- monophosphate synthase/orotate
phosphoribosyltransferase
Length = 267
Score = 438 bits (1126), Expect = e-123
Identities = 218/262 (83%), Positives = 235/262 (89%)
Query: 1 MSTKSYTSRAETHASPVASKLLRLMDEKKTNLCASLDVRSTDELLKLVETLGPYICLLKT 60
MS +Y RA TH SPVA+KL +M EK+TNLCASLDVR+T ELL+LVE LGP ICLLKT
Sbjct: 1 MSKATYKERAATHPSPVAAKLFNIMHEKQTNLCASLDVRTTKELLELVEALGPKICLLKT 60
Query: 61 HVDILDDFSYEGTVVPLKALAEKYKFLIFEDRKFADIGNTVKLQYTSGVYRIAEWSDITN 120
HVDIL DFS EGTV PLKAL+ KY FL+FEDRKFADIGNTVKLQY++GVYRIAEW+DITN
Sbjct: 61 HVDILTDFSMEGTVKPLKALSAKYNFLLFEDRKFADIGNTVKLQYSAGVYRIAEWADITN 120
Query: 121 AHGVTGAGIVAGLKQGAQEVTKEPRGLLMLAELSSKGSLAHGEYTKGTVDIAKSDKDFVI 180
AHGV G GIV+GLKQ A+EVTKEPRGLLMLAELS KGSLA GEYTKGTVDIAKSDKDFVI
Sbjct: 121 AHGVVGPGIVSGLKQAAEEVTKEPRGLLMLAELSCKGSLATGEYTKGTVDIAKSDKDFVI 180
Query: 181 GFIAQNDMGGREEGFDWLIMTPGVGLDDKGDALGQQYRTVDEVVSGGSDIIIVGRGLFAK 240
GFIAQ DMGGR+EG+DWLIMTPGVGLDDKGDALGQQYRTVD+VVS GSDIIIVGRGLFAK
Sbjct: 181 GFIAQRDMGGRDEGYDWLIMTPGVGLDDKGDALGQQYRTVDDVVSTGSDIIIVGRGLFAK 240
Query: 241 GRDPKVEGERYRNAGWEAYQKR 262
GRD KVEGERYR AGWEAY +R
Sbjct: 241 GRDAKVEGERYRKAGWEAYLRR 262
>SPCC330.05c [F] KOG1377 Uridine 5'- monophosphate synthase/orotate
phosphoribosyltransferase
Length = 264
Score = 281 bits (718), Expect = 9e-76
Identities = 143/262 (54%), Positives = 195/262 (73%), Gaps = 7/262 (2%)
Query: 4 KSYTSRAETHASPVASKLLRLMDEKKTNLCASLDVRSTDELLKLVETLGPYICLLKTHVD 63
+SY++RAE +P+A +LL LM+EK++NL ++D+ E+L+LV+ +GPY+C++KTH+D
Sbjct: 7 QSYSARAEGMKNPIAKELLALMEEKQSNLSVAVDLTKKSEILELVDKIGPYVCVIKTHID 66
Query: 64 ILDDFSYEGTVVPLKALAEKYKFLIFEDRKFADIGNTVKLQYTSGVYRIAEWSDITNAHG 123
+++DF + V L AL +K++FLIFEDRKFADIGNTVKLQY SGVY+IA W+ ITN H
Sbjct: 67 VVEDFDQD-MVEKLVALGKKHRFLIFEDRKFADIGNTVKLQYASGVYKIASWAHITNCHT 125
Query: 124 VTGAGIVAGLKQGAQEVTKEPRGLLMLAELSSKGSLAHGEYTKGTVDIAKSDKDFVIGFI 183
V G GI+ GLK+ + RGLL+LAE+SSKGSLA G YT+ T++ + DF GFI
Sbjct: 126 VPGEGIIQGLKEVGLPL---GRGLLLLAEMSSKGSLATGSYTEKTLEWFEKHTDFCFGFI 182
Query: 184 AQNDMGGREEGFDWLIMTPGVGLDDKGDALGQQYRTVDEV-VSGGSDIIIVGRGLFAKGR 242
A + D++ M+PG+GLD KGD LGQQYRT +EV V+ GSDIIIVGRG++ GR
Sbjct: 183 AGRRFPNLQS--DYITMSPGIGLDVKGDGLGQQYRTPEEVIVNCGSDIIIVGRGVYGAGR 240
Query: 243 DPKVEGERYRNAGWEAYQKRIS 264
+P VE +RYR AGW+AYQ+R+S
Sbjct: 241 NPVVEAKRYREAGWKAYQQRLS 262
>Hs4507835 [F] KOG1377 Uridine 5'- monophosphate synthase/orotate
phosphoribosyltransferase
Length = 480
Score = 238 bits (607), Expect = 7e-63
Identities = 134/261 (51%), Positives = 179/261 (68%), Gaps = 10/261 (3%)
Query: 5 SYTSRAET-HASPVASKLLRLMDEKKTNLCASLDVRSTDELLKLVETLGPYICLLKTHVD 63
S+ +RAE PVASKLLRLM +K+TNLC S DV ELL+L + LGP IC+LKTHVD
Sbjct: 226 SFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVD 285
Query: 64 ILDDFSYEGTVVPLKALAEKYKFLIFEDRKFADIGNTVKLQYTSGVYRIAEWSDITNAHG 123
IL+DF+ + + L LA+ ++FLIFEDRKFADIGNTVK QY G+++IA W+D+ NAH
Sbjct: 286 ILNDFTLD-VMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHV 344
Query: 124 VTGAGIVAGLKQGAQEVTKEPRGLLMLAELSSKGSLAHGEYTKGTVDIAKSDKDFVIGFI 183
V G+G+V GL++ + RG L++AE+SS GSLA G+YT+ V +A+ +FV+GFI
Sbjct: 345 VPGSGVVKGLQEVGLPL---HRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFI 401
Query: 184 AQNDMGGREEGFDWLIMTPGVGLDDKGDALGQQYRTVDEVV-SGGSDIIIVGRGLFAKGR 242
+ + + + E +L +TPGV L+ GD LGQQY + EV+ GSDIIIVGRG+ +
Sbjct: 402 SGSRVSMKPE---FLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIIS-AA 457
Query: 243 DPKVEGERYRNAGWEAYQKRI 263
D E YR A WEAY R+
Sbjct: 458 DRLEAAEMYRKAAWEAYLSRL 478
>7300695 [F] KOG1377 Uridine 5'- monophosphate synthase/orotate
phosphoribosyltransferase
Length = 493
Score = 212 bits (539), Expect = 5e-55
Identities = 117/264 (44%), Positives = 168/264 (63%), Gaps = 8/264 (3%)
Query: 5 SYTSRAETHASPVASKLLRLMDEKKTNLCASLDVRSTDELLKLVETLGPYICLLKTHVDI 64
+Y +RA S VA +L L+ K+TNLC + D+ DE+L + + GPYICLLKTHVDI
Sbjct: 233 TYENRANLAKSAVAKRLFNLIASKQTNLCLAADLTHADEILDVADKCGPYICLLKTHVDI 292
Query: 65 LDDFSYEGTVVPLKALAEKYKFLIFEDRKFADIGNTVKLQYTSGVYRIAEWSDITNAHGV 124
++DFS + + L+ALA+++ FL+ EDRKFADIGNTV LQY G+Y+I+ W+D+ AH +
Sbjct: 293 VEDFS-DKFIADLQALAQRHNFLLMEDRKFADIGNTVSLQYGKGIYKISSWADLVTAHTL 351
Query: 125 TGAGIVAGLKQGAQE-VTKEPRGLLMLAELSSKGSLAHGEYTKGTVDIAK--SDKDFVIG 181
G I+ GLK G E + RG+ +LAE+S+ G+L +Y + + IA +D DFV G
Sbjct: 352 PGRSILQGLKAGLGEGGAGKERGVFLLAEMSASGNLIDAKYKENSNKIATEGADVDFVAG 411
Query: 182 FIAQNDMGGREEGFDWLIMTPGVGLDDKGDALGQQYRTVDEVV-SGGSDIIIVGRGLFAK 240
+ Q+ G L +TPGV +D+ D LGQQY++ + VV G+DI +VGRG+ K
Sbjct: 412 VVCQSSDAFAFPGL--LQLTPGVKIDEGVDQLGQQYQSPEHVVKERGADIGVVGRGIL-K 468
Query: 241 GRDPKVEGERYRNAGWEAYQKRIS 264
PK + YR+ W AYQ R++
Sbjct: 469 ASSPKQAAQTYRDRLWAAYQDRVA 492
>CE00638 [F] KOG1377 Uridine 5'- monophosphate synthase/orotate
phosphoribosyltransferase
Length = 497
Score = 174 bits (442), Expect = 9e-44
Identities = 100/247 (40%), Positives = 150/247 (60%), Gaps = 9/247 (3%)
Query: 15 SPVASKLLRLMDEKKTNLCASLDVRSTDELLKLVETLGPYICLLKTHVDILDDFSYEGTV 74
S + K+L +M KK+NLC ++D + ++ L+++E GP++ +K H D + DF+ E T
Sbjct: 249 SALIKKILGIMRRKKSNLCLAVDYTTVEQCLQMIELAGPFVLAIKLHADAITDFNEEFT- 307
Query: 75 VPLKALAEKYKFLIFEDRKFADIGNTVKLQYTSGVYRIAEWSDITNAHGVTGAGIVAGL- 133
L +A F+IFEDRKF D GNT LQ T G +IA W+D+ H V G+ +AG+
Sbjct: 308 RKLTTMANDMDFIIFEDRKFGDTGNTNLLQLT-GAQKIANWADVVTVHAVQGSDSIAGVF 366
Query: 134 KQGAQEVTKEPRGLLMLAELSSKGSLAHGE-YTKGTVDIAKSDKDFVIGFIAQNDMGGRE 192
++ A++ T G+L++A+LS+KGSL E YT+ V IA ++D + GFI Q +
Sbjct: 367 RKLAKDPTYRLSGVLLIAQLSTKGSLTALEGYTETAVKIANENRDVISGFITQTRVSACS 426
Query: 193 EGFDWLIMTPGVGLDDKGDALGQQYRTVDEVVS-GGSDIIIVGRGLFAKGRDPKVEGERY 251
+ +W TPGV LD K D+ GQQ+R VDE + +DIIIVGRG+ +P + +RY
Sbjct: 427 DLLNW---TPGVNLDAKSDSAGQQWRGVDEAIEVQQNDIIIVGRGV-TSSSEPVQQLKRY 482
Query: 252 RNAGWEA 258
R W+A
Sbjct: 483 RQIAWDA 489
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,792,391
Number of Sequences: 60738
Number of extensions: 672443
Number of successful extensions: 1312
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1289
Number of HSP's gapped (non-prelim): 5
length of query: 267
length of database: 30,389,216
effective HSP length: 104
effective length of query: 163
effective length of database: 24,072,464
effective search space: 3923811632
effective search space used: 3923811632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)