ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5930 good O KOG3206 Posttranslational modification, protein turnover, chaperones Alpha-tubulin folding cofactor B
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5930 2038166 2037330 -279
(279 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL148c [O] KOG3206 Alpha-tubulin folding cofactor B 98 1e-20
7302461 [O] KOG3206 Alpha-tubulin folding cofactor B 89 5e-18
CE10958 [O] KOG3206 Alpha-tubulin folding cofactor B 82 8e-16
Hs17456232 [O] KOG3206 Alpha-tubulin folding cofactor B 81 2e-15
Hs4502849 [O] KOG3206 Alpha-tubulin folding cofactor B 80 2e-15
At3g10220 [O] KOG3206 Alpha-tubulin folding cofactor B 66 6e-11
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 54 2e-07
>YNL148c [O] KOG3206 Alpha-tubulin folding cofactor B
Length = 254
Score = 97.8 bits (242), Expect = 1e-20
Identities = 75/240 (31%), Positives = 110/240 (45%), Gaps = 25/240 (10%)
Query: 34 VEIISDLVNTQIFVKPGTSWDHLGQRLNELTGVDVQDMKLVINGNAQNSKYL-------- 85
V I S+LV T+ + RL +TGV+ +DM++V+ N +
Sbjct: 4 VVIESELVRTEKELPNSLKLRQFKDRLYHVTGVEPEDMEIVVKRQYDNKEIYSTKKGGAY 63
Query: 86 ----KDLKDQKVEKIQSIKVIDTNENSLASQLKNDLLHANSDDVSFRYTMDDYENRRDSV 141
+D K E+ + V D+N S+++QL S +V + +DY R SV
Sbjct: 64 SNEDEDANFLKGEEELIVVVTDSNAQSISNQLATQAEGIPSMEV---ISEEDYLRRDQSV 120
Query: 142 LQWKKDNKLGKFNPEYRSKMEEQLQLNIDKA-ELLQKHVGERCRVLSNEETTTDSTKVPE 200
L+WK + G+FN +S+ + + A E L +G CRV T D +
Sbjct: 121 LRWKMAHGYGRFNAAQQSQRAALAKQDEAYAREQLTAAIGRHCRV------TVDGSA--P 172
Query: 201 RRGWLRYVGKVQEISNTDVWCGIEFDEPDGKNNGTFQGTKYFGPVKKNYGGFVRPAVVEV 260
R LRYVG + + WCG+EF E GKN+G G FGPV +G FVRP VE+
Sbjct: 173 REAILRYVGPLP-LDVMGTWCGVEFPEAAGKNDGRINGVTLFGPVAPGHGSFVRPRAVEI 231
>7302461 [O] KOG3206 Alpha-tubulin folding cofactor B
Length = 244
Score = 89.4 bits (220), Expect = 5e-18
Identities = 62/149 (41%), Positives = 81/149 (53%), Gaps = 13/149 (8%)
Query: 127 FRYTMDDYENRRDSVLQWKKDNKLGKFNPEYRSKMEEQLQLNIDKAELLQKHVGERCRVL 186
F + D YE R DSV + K N++GK+N E + EE+ +L +AE +QK E C +
Sbjct: 106 FELSKDQYEQRTDSVRNYLKINRMGKYNDEEMQQAEEKKRL---QAEEIQKR-AELCVLG 161
Query: 187 SNEETTTDSTKVPERRGWLRYVGKVQEISNTDVWCGIEFDEPDGKNNGTFQGTKYFGPVK 246
E T P RRG +RY G ++ + + G+E+DEP GKNNG+F G YF
Sbjct: 162 GRCEVTVPGN--PTRRGTIRYNGPLE--GKSGHFIGVEYDEPLGKNNGSFGGKAYF-TCA 216
Query: 247 KNYGGFVRPAVVEVGPQFTP---LADDEL 272
NYGGFV P V VG F P DDEL
Sbjct: 217 PNYGGFVSPLSVTVG-DFPPEDFNMDDEL 244
>CE10958 [O] KOG3206 Alpha-tubulin folding cofactor B
Length = 229
Score = 82.0 bits (201), Expect = 8e-16
Identities = 77/252 (30%), Positives = 118/252 (46%), Gaps = 40/252 (15%)
Query: 33 DVEIISDLVNTQIFVK--PGTSWDHLGQRLNELTGVDVQDMKL-VINGNAQ-------NS 82
D+EI ++ + + K G S + L ++L + G V M++ + +G+ Q +
Sbjct: 6 DLEITTNATDFPMEKKYPAGMSLNDLKKKLELVVGTTVDSMRIQLFDGDDQLKGELTDGA 65
Query: 83 KYLKDLKDQKVEKIQSIKVIDTNENSLASQLKNDLLHANSDDVSFRYTMDD--YENRRDS 140
K LKDL + +I ++ V NE+ + + +Y M D Y R DS
Sbjct: 66 KSLKDLGVRDGYRIHAVDVTGGNEDF------------KDESMVEKYEMSDDTYGKRTDS 113
Query: 141 VLQWKKDNKLGKFNPEYRSKMEEQLQLNIDKAELLQKHVGERCRVLSNEETTTDSTKVPE 200
V WKK K+ + E +LN + A+ + VG RC V +
Sbjct: 114 VRAWKK--KMQEEQGSAAPMENESDKLNEEAAKNIM--VGNRCEVTVGAQMA-------- 161
Query: 201 RRGWLRYVGKVQEISNTDVWCGIEFDEPDGKNNGTFQGTKYFGPVKKNYGGFVRPAVVEV 260
RRG + YVG + VW G+++DEP GKN+G+ G +YF K YGGFVRP V+V
Sbjct: 162 RRGEVAYVGATK--FKEGVWVGVKYDEPVGKNDGSVAGVRYFDCDPK-YGGFVRPVDVKV 218
Query: 261 GPQFTPLADDEL 272
G F L+ DE+
Sbjct: 219 G-DFPELSIDEI 229
>Hs17456232 [O] KOG3206 Alpha-tubulin folding cofactor B
Length = 244
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/145 (35%), Positives = 79/145 (54%), Gaps = 17/145 (11%)
Query: 123 DDVS----FRYTMDDYENRRDSVLQWKKDNKLGKFNPEYRSKMEEQL--QLNIDKAELLQ 176
+DVS + + + Y+ R+D+V + K +KLG++N E R++ E + +L +KA+
Sbjct: 99 EDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASS 158
Query: 177 KHVGERCRVLSNEETTTDSTKVPERRGWLRYVGKVQEISNTDVWCGIEFDEPDGKNNGTF 236
VG RC V + ++ RRG + YVG W G+ +DEP GKN+G+
Sbjct: 159 IPVGSRCEVRAAGQSP--------RRGTVMYVGLTD--FKPGYWIGVRYDEPLGKNDGSV 208
Query: 237 QGTKYFGPVKKNYGGFVRPAVVEVG 261
G +YF + YG FV+PAVV VG
Sbjct: 209 NGKRYF-ECQAKYGAFVKPAVVTVG 232
>Hs4502849 [O] KOG3206 Alpha-tubulin folding cofactor B
Length = 244
Score = 80.5 bits (197), Expect = 2e-15
Identities = 51/145 (35%), Positives = 78/145 (53%), Gaps = 17/145 (11%)
Query: 123 DDVS----FRYTMDDYENRRDSVLQWKKDNKLGKFNPEYRSKMEEQL--QLNIDKAELLQ 176
+DVS + + + Y+ R+D+V + K KLG++N E R++ E + +L +KA+
Sbjct: 99 EDVSRVEKYTISQEAYDQRQDTVRSFLKRRKLGRYNEEERAQQEAEAAQRLAEEKAQASS 158
Query: 177 KHVGERCRVLSNEETTTDSTKVPERRGWLRYVGKVQEISNTDVWCGIEFDEPDGKNNGTF 236
VG RC V + ++ RRG + YVG W G+ +DEP GKN+G+
Sbjct: 159 IPVGSRCEVRAAGQSP--------RRGTVMYVGLTD--FKPGYWIGVRYDEPLGKNDGSV 208
Query: 237 QGTKYFGPVKKNYGGFVRPAVVEVG 261
G +YF + YG FV+PAVV VG
Sbjct: 209 NGKRYF-ECQAKYGAFVKPAVVTVG 232
>At3g10220 [O] KOG3206 Alpha-tubulin folding cofactor B
Length = 240
Score = 65.9 bits (159), Expect = 6e-11
Identities = 50/151 (33%), Positives = 80/151 (52%), Gaps = 29/151 (19%)
Query: 127 FRYTMDDYENRRDSVLQWKKDNKLGKFNP---EYRSKMEEQLQLNIDKAELLQKHVGERC 183
+ + +DY R DS ++K+ K NP E ++ ME+ L NI VG+RC
Sbjct: 114 YNISEEDYAKRTDSFRKFKE--KRVSQNPVAAEAKNYMED-LCANIK--------VGDRC 162
Query: 184 RVLSNEETTTDSTKVPERRGWLRYVGKVQEISNTDVWCGIEFDEPDGKNNGTFQGTKYFG 243
+V + E+RG ++YVG+ + + W GI++DEP GK++G +GT++F
Sbjct: 163 QV-----------EPGEKRGMVKYVGRAESLG-PGYWVGIQYDEPLGKHDGMVKGTRFF- 209
Query: 244 PVKKNYGGFVRPAVVEVG--PQFTPLADDEL 272
+ GG VRP V+VG P+ P +DE+
Sbjct: 210 ECPRLQGGMVRPDKVKVGDYPERDPFEEDEI 240
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/62 (46%), Positives = 35/62 (55%), Gaps = 3/62 (4%)
Query: 201 RRGWLRYVGKVQEISNTDVWCGIEFDEPDGKNNGTFQGTKYFGPVKKNYGGFVRPAVVEV 260
R G LRY+G+ Q WCG+E DEP GKN+GT +YF K YG FV A V +
Sbjct: 252 RPGILRYLGETQFAPGN--WCGVELDEPSGKNDGTVDDIRYF-ECKPKYGVFVPIAKVSL 308
Query: 261 GP 262
P
Sbjct: 309 SP 310
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.133 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,678,217
Number of Sequences: 60738
Number of extensions: 792836
Number of successful extensions: 2058
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2043
Number of HSP's gapped (non-prelim): 9
length of query: 279
length of database: 30,389,216
effective HSP length: 105
effective length of query: 174
effective length of database: 24,011,726
effective search space: 4178040324
effective search space used: 4178040324
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)