ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV5981 good C KOG2450 Energy production and conversion Aldehyde dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV5981 2053941 2052421 -507
(507 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL061w [C] KOG2450 Aldehyde dehydrogenase 739 0.0
YOR374w [C] KOG2450 Aldehyde dehydrogenase 591 e-168
YER073w [C] KOG2450 Aldehyde dehydrogenase 588 e-168
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 476 e-134
CE29393 [C] KOG2450 Aldehyde dehydrogenase 459 e-129
CE23852 [C] KOG2450 Aldehyde dehydrogenase 458 e-128
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 439 e-123
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 432 e-121
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 432 e-121
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 430 e-120
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 429 e-120
7297513 [C] KOG2450 Aldehyde dehydrogenase 429 e-120
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 425 e-119
7301524 [C] KOG2450 Aldehyde dehydrogenase 425 e-119
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 422 e-118
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 420 e-117
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 407 e-113
YMR170c [C] KOG2450 Aldehyde dehydrogenase 405 e-113
YMR169c [C] KOG2450 Aldehyde dehydrogenase 399 e-111
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 398 e-111
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 397 e-110
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 397 e-110
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 395 e-110
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 343 5e-94
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 319 5e-87
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 308 1e-83
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 298 1e-80
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 298 2e-80
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 295 8e-80
CE06980 [C] KOG2450 Aldehyde dehydrogenase 291 2e-78
CE24573 [C] KOG2450 Aldehyde dehydrogenase 290 4e-78
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 285 9e-77
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 285 9e-77
CE07233 [C] KOG2450 Aldehyde dehydrogenase 283 3e-76
7301355 [C] KOG2451 Aldehyde dehydrogenase 276 7e-74
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 273 3e-73
YBR006w [C] KOG2451 Aldehyde dehydrogenase 261 2e-69
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 259 5e-69
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 259 7e-69
CE10542 [C] KOG2451 Aldehyde dehydrogenase 234 2e-61
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 223 7e-58
CE01232 [C] KOG2453 Aldehyde dehydrogenase 211 2e-54
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 209 8e-54
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 204 3e-52
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 203 6e-52
7293810 [C] KOG2453 Aldehyde dehydrogenase 200 4e-51
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 198 1e-50
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 195 2e-49
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 192 1e-48
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 185 2e-46
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 173 5e-43
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 165 1e-40
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 157 5e-38
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 154 2e-37
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 153 7e-37
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 147 3e-35
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 145 1e-34
Hs20546780 [C] KOG2450 Aldehyde dehydrogenase 140 4e-33
YMR110c [C] KOG2456 Aldehyde dehydrogenase 135 2e-31
CE27441 [C] KOG2456 Aldehyde dehydrogenase 134 2e-31
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 134 3e-31
CE13415 [C] KOG2456 Aldehyde dehydrogenase 126 7e-29
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 124 3e-28
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 124 3e-28
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 124 4e-28
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 122 1e-27
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 120 6e-27
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 120 6e-27
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 118 2e-26
7304212 [C] KOG2456 Aldehyde dehydrogenase 103 6e-22
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 96 1e-19
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 95 3e-19
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 73 9e-13
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 71 3e-12
Hs20479244 [C] KOG2450 Aldehyde dehydrogenase 70 7e-12
At5g62530 [C] KOG2451 Aldehyde dehydrogenase 53 9e-07
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 739 bits (1909), Expect = 0.0
Identities = 355/491 (72%), Positives = 425/491 (86%), Gaps = 1/491 (0%)
Query: 17 DAVSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXX 76
+ V ITLPNGLTY+QPTGLFINN+F+K+QDGKT VE+PSTE + EV SAT++
Sbjct: 10 EPVKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAI 69
Query: 77 XXXXXXFN-SEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLV 135
F+ +EW+T DP++RG LL KLAD +E+Q +L++SIE+ DNGKTLALARGDV +
Sbjct: 70 ECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIA 129
Query: 136 IDYIRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVA 195
I+ +R AA YADK+ GRTINTGDGY NFT EP+GVCGQIIPWNFP+MML+WKIAPAL
Sbjct: 130 INCLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAM 189
Query: 196 GNTVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTG 255
GN ILKPA+ TPLNAL+FASLCK+ GIPAGVVNIVPGPGR+VG +TN P+IRK+AFTG
Sbjct: 190 GNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTG 249
Query: 256 STDIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSG 315
ST++G+ VA+ +++SNLKK+TLELGGKSAHLVF+DANIKKT+PNLVNGIFKNAGQICSSG
Sbjct: 250 STEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSG 309
Query: 316 SRIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEG 375
SRIYVQ+ IYD+LL+ FK YLETEIKVG+PFD++NFQ AI N+ QF+TI+NYIDIGKKEG
Sbjct: 310 SRIYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEG 369
Query: 376 ASILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSE 435
A ILTGGE+VG+KGYFI+PTVFY+V EDMRIVKEEIFGPVVT++KF T++E V +AN SE
Sbjct: 370 AKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSE 429
Query: 436 FGLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFES 495
FGLG+GIETE++S LKVAK LKAGTVWINTYNDFD+ VPFGG KQSGYGREMGEE + +
Sbjct: 430 FGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHA 489
Query: 496 YTQIKAVRIKL 506
YT++KAVRIKL
Sbjct: 490 YTEVKAVRIKL 500
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 591 bits (1523), Expect = e-168
Identities = 288/490 (58%), Positives = 373/490 (75%), Gaps = 3/490 (0%)
Query: 19 VSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXX 78
V I LPNGL Y+QPTGLFINN+F+ S+ KT +V NPSTEE I +
Sbjct: 31 VPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQA 90
Query: 79 XXXXF-NSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVID 137
F N W+ +DP RG L++LA+LIE K++IASIE+ DNGK ++ +RGDV LVI+
Sbjct: 91 ADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVIN 150
Query: 138 YIRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGN 197
Y++S+AG+ADK+ GR I+TG + ++T ++PLGVCGQIIPWNFPL+M +WKIAPALV GN
Sbjct: 151 YLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGN 210
Query: 198 TVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGST 257
TV+LK A TPL+AL+ + +AGIP GV+NIV G G+ VG+ ITNHPKI+K+AFTGST
Sbjct: 211 TVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGST 270
Query: 258 DIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSR 317
GR + ++A + LKKVTLELGGKS ++VF DA +KK + N++ GI+ N+G++C +GSR
Sbjct: 271 ATGRHI-YQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSR 329
Query: 318 IYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGAS 377
+YV+++IYD+ + EFK E+ IKVG PFDES FQ A ++ Q IL Y+DIGK EGA+
Sbjct: 330 VYVEESIYDKFIEEFKAASES-IKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGAT 388
Query: 378 ILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFG 437
++TGGER+G+KGYFIKPTVF +VKEDMRIVKEEIFGPVVT++KF + DE + +ANDSE+G
Sbjct: 389 LITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYG 448
Query: 438 LGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYT 497
L AGI T NI+ ALKVA R+ AGTVWINTYNDF AVPFGG+ SG GREM +A ++Y
Sbjct: 449 LAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYL 508
Query: 498 QIKAVRIKLD 507
Q+KAVR KLD
Sbjct: 509 QVKAVRAKLD 518
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 588 bits (1515), Expect = e-168
Identities = 285/489 (58%), Positives = 364/489 (74%), Gaps = 2/489 (0%)
Query: 19 VSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXX 78
V ITLPNG TY+QPTGLFIN +F+ S+ KT V NPS EE I V A
Sbjct: 30 VPITLPNGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAA 89
Query: 79 XXXXFNSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDY 138
F ++WS ++P+ R LF LADL+E +E +A+IES DNGK+L ARGDV LV Y
Sbjct: 90 AKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDVALVSKY 149
Query: 139 IRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNT 198
+RS G+ADK+ G I+TG + ++ KEPLGVCGQIIPWNFPL+M SWKI PAL GNT
Sbjct: 150 LRSCGGWADKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNT 209
Query: 199 VILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTD 258
V+LKPA TPL+ALF + LC+EAGIPAGVVNI+PG GR VG+ ++ HP ++KIAFTGST
Sbjct: 210 VVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTA 269
Query: 259 IGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRI 318
GR + +K A +KKVTLELGGKS ++VF DA++ K + N+ GIF N+G++C +GSRI
Sbjct: 270 TGRHI-MKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRI 328
Query: 319 YVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASI 378
Y+QDT+Y+++L + K Y E+ +KVG PFDE FQ A + Q IL+Y+D+ K EGA +
Sbjct: 329 YIQDTVYEEVLQKLKDYTES-LKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARL 387
Query: 379 LTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGL 438
+TGG R G+KGYF+KPTVF +VK DMRIVKEE+FGP+VT+SKFSTVDE +A+ANDS++GL
Sbjct: 388 VTGGARHGSKGYFVKPTVFADVKGDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGL 447
Query: 439 GAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQ 498
AGI T +I+ A+ V+KR+KAGTVWINTYN+F VPFGG+ QSG GREMGE A +YTQ
Sbjct: 448 AAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQ 507
Query: 499 IKAVRIKLD 507
K+VRI +D
Sbjct: 508 TKSVRIAID 516
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 476 bits (1225), Expect = e-134
Identities = 244/492 (49%), Positives = 318/492 (64%), Gaps = 3/492 (0%)
Query: 17 DAVSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXX 76
D V IT+P G TY QP GLFINNQ + S G +KV +PSTE++I EV A +
Sbjct: 7 DHVEITVPTGKTYIQPVGLFINNQHVDSVHGGRVKVYSPSTEKLICEVADADEEDVDIAV 66
Query: 77 XXXXXXFNSE--WSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGL 134
F ++ W +RG L +LAD IE E +ASIE+ DNGK++ LARGDV
Sbjct: 67 KVARAAFQTDAPWRKFSSAQRGRCLSRLADCIEQNLEYLASIETLDNGKSITLARGDVQA 126
Query: 135 VIDYIRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALV 194
D R G+ADK G+TI T +T EP+GVCGQIIPWNFP +M +WKIAPA+
Sbjct: 127 AADCFRYYGGWADKDYGQTIETDIKRFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVA 186
Query: 195 AGNTVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFT 254
GNT+ILK A TPL+AL E G P GV+N++ G GR G+ I++H I K+AFT
Sbjct: 187 CGNTIILKTAELTPLSALCLTKFVPECGFPPGVINVLSGDGRRCGNAISSHMDIDKVAFT 246
Query: 255 GSTDIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSS 314
GST +GR V AA SNLKKVTLELGGKS ++VF DA++ GIF N+GQ+C +
Sbjct: 247 GSTGVGRMVMRAAASSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCA 306
Query: 315 GSRIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKE 374
GSR+YVQ+ +YD+ + +T +KVG PF E FQ A +K Q+E I++YI+ G
Sbjct: 307 GSRVYVQEDVYDEFIKRMVAKAKT-LKVGDPFAEDTFQGAQVSKQQYERIVSYIESGIAH 365
Query: 375 GASILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDS 434
GA + GG+R GN GYF++PT+ NV EDM + KEEIFGPV+ + KF T++EA+ N+S
Sbjct: 366 GAKLEIGGKRHGNLGYFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNS 425
Query: 435 EFGLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFE 494
+GL AG+ T NI+ A+KV+ L+AGTVW+N YN +PFGGYK+SG GRE+G
Sbjct: 426 TYGLAAGVHTNNITNAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRELGSYGLT 485
Query: 495 SYTQIKAVRIKL 506
+YTQ KAV I L
Sbjct: 486 NYTQTKAVHINL 497
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 459 bits (1182), Expect = e-129
Identities = 233/489 (47%), Positives = 326/489 (66%), Gaps = 6/489 (1%)
Query: 23 LPNGLTYQQP--TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXX 80
+P GL+ +P TG+FINN+F+ ++ GKT + NP+ +++ +V
Sbjct: 18 VPPGLSNMKPQYTGIFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKAAQ 77
Query: 81 XXFN--SEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVID 137
F SEW MD +RG LL +LADL+E + ++AS+ES DNGK A+A D+ L I
Sbjct: 78 NAFRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIK 137
Query: 138 YIRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGN 197
+R ADK G+TI Y +T EP+GVCGQIIPWNFPL+M +WK+ PAL GN
Sbjct: 138 TLRLLRRMADKNHGKTIPIEGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGN 197
Query: 198 TVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGST 257
TV++K A TPL+AL A+L KEAG P GVVNI+PG G + G I++H + K+AFTGST
Sbjct: 198 TVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGST 257
Query: 258 DIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSR 317
++GR V AA+SN+KKVTLELGGKS +++F DA++ ++ +G+F N GQ C +GSR
Sbjct: 258 EVGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSR 317
Query: 318 IYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGAS 377
+V+ IYD ++ K E + +G PFD Q + Q ETIL YI GKK+GA
Sbjct: 318 TFVEGKIYDDFVARSKELAEKAV-IGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQ 376
Query: 378 ILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFG 437
++TGG + G++G+F+KPT+F NVK+ M I +EEIFGPV+TI +F T++E V AN++ +G
Sbjct: 377 LVTGGAKHGDQGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYG 436
Query: 438 LGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYT 497
L AG+ T++I AL +A +AG+VW+N Y+ FDAA PFGG+KQSG GRE+GE E+YT
Sbjct: 437 LAAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEAYT 496
Query: 498 QIKAVRIKL 506
++K V IK+
Sbjct: 497 EVKTVTIKV 505
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 458 bits (1178), Expect = e-128
Identities = 225/475 (47%), Positives = 324/475 (67%), Gaps = 4/475 (0%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWSTMDP 92
LFINN+F+ ++ GKT + NP+ +++ +V F SEW MD
Sbjct: 59 LFINNEFVDAKSGKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDA 118
Query: 93 KKRGSLLFKLADLIEAQKELIASIESADNGKTLALARG-DVGLVIDYIRSAAGYADKLGG 151
RG LL +LADL+E + ++AS+ES DNGK A D+ + I R AGYADK G
Sbjct: 119 SHRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNHG 178
Query: 152 RTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNA 211
+TI G Y +T EP+GVCGQIIPWNFPL+M +WK+APAL GNTV++K A TPL+A
Sbjct: 179 KTIPVGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSA 238
Query: 212 LFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSN 271
L ASL KEA P GVVNI+PG G G+ I +H + K+AFTGST++G+ + AA+SN
Sbjct: 239 LHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAESN 298
Query: 272 LKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSE 331
+KKVTLELGGKS ++VF DA++++ + + +F N GQ CS+GSR +V+ IYD+ +++
Sbjct: 299 VKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFVAK 358
Query: 332 FKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYF 391
K +E + +G PFDE+ Q +++Q ETI+ YI+ GKKEGA ++TGG + G++GYF
Sbjct: 359 AKELVEKTV-IGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGDQGYF 417
Query: 392 IKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVAL 451
+KPT+F NV + M+I +EEIFGPV+ + +F +++E + AN++ +GL AG+ T +++ AL
Sbjct: 418 VKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDLNKAL 477
Query: 452 KVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
+VA ++AG+VW+N Y+ FD A PFGG+KQSG GRE+GE +YT++K V IK+
Sbjct: 478 QVANTIRAGSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTVTIKV 532
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 439 bits (1128), Expect = e-123
Identities = 229/477 (48%), Positives = 310/477 (64%), Gaps = 4/477 (0%)
Query: 33 TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWSTM 90
T +FINN++ S+ G+ V NP+T E + EVQ A F+ S W M
Sbjct: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97
Query: 91 DPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVIDYIRSAAGYADKL 149
D +RG LL KLADL+E + ++A++ES + GK A D+ VI R AG+ADK+
Sbjct: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157
Query: 150 GGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPL 209
G TI Y FT EP+GVCGQIIPWNFPL+M +WKIAPAL GNTV++KPA TPL
Sbjct: 158 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217
Query: 210 NALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQ 269
+AL+ +L KEAG P GV+NI+PG G + G I +H I KIAFTGST++G+ + A +
Sbjct: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277
Query: 270 SNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLL 329
SNLK+VTLELGGKS +++F DA++ + G+F N GQ C++GSRI+V+++IY++ +
Sbjct: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337
Query: 330 SEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG 389
+ I VGSPFD + Q +K Q+ IL I G EGA + GG+ +G KG
Sbjct: 338 RRSVERAKRRI-VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKG 396
Query: 390 YFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISV 449
+FI+PTVF NV +DMRI KEEIFGPV I +F T+DE + AN+S+FGL A + T +I+
Sbjct: 397 FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINK 456
Query: 450 ALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
AL V+ ++AGTVWIN YN +A PFGG+K SG GREMGE Y+++K V +K+
Sbjct: 457 ALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 432 bits (1110), Expect = e-121
Identities = 226/479 (47%), Positives = 310/479 (64%), Gaps = 4/479 (0%)
Query: 31 QPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWS 88
Q T +FINN++ S GK V NP+TEE + +V+ + F S W
Sbjct: 19 QYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWR 78
Query: 89 TMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALAR-GDVGLVIDYIRSAAGYAD 147
TMD +RG LL+KLADLIE + L+A++ES + GK + A D+ I +R AG+AD
Sbjct: 79 TMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGWAD 138
Query: 148 KLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPT 207
K+ GRTI + +T EP+GVCGQIIPWNFPL+ML WKI PAL GNTV++KPA T
Sbjct: 139 KIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQT 198
Query: 208 PLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKA 267
PL AL ASL KEAG P GVVNIVPG G + G I++H I K+AFTGST++G+ + A
Sbjct: 199 PLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAA 258
Query: 268 AQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQ 327
+SNLK+VTLELGGKS +V DA++ + +G+F + GQ C + SRI+V+++IYD+
Sbjct: 259 GKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDE 318
Query: 328 LLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGN 387
+ + I +G+P Q +K Q++ IL+ I+ GKKEGA + GG GN
Sbjct: 319 FVRRSVERAKKYI-LGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGN 377
Query: 388 KGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENI 447
KGYF++PTVF NV ++MRI KEEIFGPV I KF ++D+ + AN++ +GL AG+ T++I
Sbjct: 378 KGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDI 437
Query: 448 SVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
A+ ++ L+AGTVW+N Y A PFGG+K SG GRE+GE F YT++K V +K+
Sbjct: 438 DKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 432 bits (1110), Expect = e-121
Identities = 226/479 (47%), Positives = 310/479 (64%), Gaps = 4/479 (0%)
Query: 31 QPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWS 88
Q T +FINN++ S GK V NP+TEE + +V+ + F S W
Sbjct: 19 QYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWR 78
Query: 89 TMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALAR-GDVGLVIDYIRSAAGYAD 147
TMD +RG LL+KLADLIE + L+A++ES + GK + A D+ I +R AG+AD
Sbjct: 79 TMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWAD 138
Query: 148 KLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPT 207
K+ GRTI + +T EP+GVCGQIIPWNFPL+ML WKI PAL GNTV++KPA T
Sbjct: 139 KIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQT 198
Query: 208 PLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKA 267
PL AL ASL KEAG P GVVNIVPG G + G I++H I K+AFTGST++G+ + A
Sbjct: 199 PLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAA 258
Query: 268 AQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQ 327
+SNLK+VTLELGGKS +V DA++ + +G+F + GQ C + SRI+V+++IYD+
Sbjct: 259 GKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDE 318
Query: 328 LLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGN 387
+ + I +G+P Q +K Q++ IL+ I+ GKKEGA + GG GN
Sbjct: 319 FVRRSVERAKKYI-LGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGN 377
Query: 388 KGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENI 447
KGYF++PTVF NV ++MRI KEEIFGPV I KF ++D+ + AN++ +GL AG+ T++I
Sbjct: 378 KGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDI 437
Query: 448 SVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
A+ ++ L+AGTVW+N Y A PFGG+K SG GRE+GE F YT++K V +K+
Sbjct: 438 DKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 430 bits (1105), Expect = e-120
Identities = 233/491 (47%), Positives = 313/491 (63%), Gaps = 6/491 (1%)
Query: 19 VSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXX 78
VSI PNG + +QP GL+IN ++ KS + T + +PS EE+I +V A +
Sbjct: 7 VSINFPNGKSVKQPIGLYINGEWHKSAE--TWETVDPSIEEVIAKVYLAGEKEIDYAVKS 64
Query: 79 XXXXFNSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLAL-ARGDVGLVID 137
F + W + ++G LL KLA+L E + +A+IE+ D+GK L ARGDV I
Sbjct: 65 AKEAFKT-WKKVPGSEKGELLMKLAELTEKHADTLAAIEAMDSGKPLVSNARGDVDGTIA 123
Query: 138 YIRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGN 197
+R AG+ADK+ G+ I TG + + P+GVCGQI+PWN+PL M WKIAPAL AGN
Sbjct: 124 LLRYCAGWADKIYGQVIPTGPEKLAYAKRTPIGVCGQIVPWNYPLNMAGWKIAPALAAGN 183
Query: 198 TVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGST 257
+I+K A TPL+ L+FA+L +EAG P GVVNI+ G G G + HP I KIAFTGST
Sbjct: 184 CIIIKSAETTPLSLLYFATLVEEAGFPKGVVNIISGLGTVAGSYMAKHPGIDKIAFTGST 243
Query: 258 DIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSR 317
+G + + A SNLK VTLE GGKS LVFEDA++ + + GI N+GQIC+S SR
Sbjct: 244 KVG-VIVQQLAASNLKAVTLECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICTSNSR 302
Query: 318 IYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGAS 377
IYVQD++YD+ + FK ++ + VG PFD++ + NK Q+ I NYI+ GKKEGA
Sbjct: 303 IYVQDSVYDKFIELFKKHVIQDYIVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKEGAK 362
Query: 378 ILTGGERVGNK-GYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEF 436
++ G E + K GYFI PT+F + E+M IVKEEIFGPVV ISKF T DEA+ AN++ +
Sbjct: 363 LVLGDEPLPLKQGYFISPTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAIEKANNTTY 422
Query: 437 GLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
GL A T+++ A +V+ L+AG V+IN+ + D PFGG K SG G E+G E Y
Sbjct: 423 GLAAMCFTKDLERAHRVSDELEAGMVFINSTENSDIQAPFGGIKMSGIGNELGSNGIEMY 482
Query: 497 TQIKAVRIKLD 507
TQIKAV I +
Sbjct: 483 TQIKAVHINFN 493
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 429 bits (1103), Expect = e-120
Identities = 227/477 (47%), Positives = 304/477 (63%), Gaps = 4/477 (0%)
Query: 33 TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWSTM 90
T +FINN++ +S+ GK NPST E I EV+ F S W +
Sbjct: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91
Query: 91 DPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARG-DVGLVIDYIRSAAGYADKL 149
D RG LL +LADL+E + +A++E+ D GK A D+ I +R AG+ADK+
Sbjct: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151
Query: 150 GGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPL 209
G+TI T D FT EP+GVCG I PWNFPL+ML WK+APAL GNT++LKPA TPL
Sbjct: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211
Query: 210 NALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQ 269
AL+ SL KEAG P GVVNIVPG G +VG I++HP+I KIAFTGST++G+ V A++
Sbjct: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271
Query: 270 SNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLL 329
SNLK+VTLELGGK+ +V DA++ + G+F N GQ C++ SR++V++ +Y + +
Sbjct: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331
Query: 330 SEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG 389
Y + VG PFD Q ++ QF+ IL I+ GKKEGA + GG + +KG
Sbjct: 332 RRSVEYAKKR-PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKG 390
Query: 390 YFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISV 449
FIKPTVF V ++MRI KEEIFGPV I KF +++E + AN +++GL A + T+N+
Sbjct: 391 LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450
Query: 450 ALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
ALK+A L++GTVWIN YN A PFGG+K SG GRE+GE A YT++K V IKL
Sbjct: 451 ALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 429 bits (1102), Expect = e-120
Identities = 218/478 (45%), Positives = 310/478 (64%), Gaps = 6/478 (1%)
Query: 33 TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWSTM 90
TG+FINN++ KS+ GK + NP+T E+I E+Q A + F S W M
Sbjct: 40 TGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRM 99
Query: 91 DPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARG-DVGLVIDYIRSAAGYADKL 149
D +RG LL++LADL+E + +AS+E+ DNGK +++ D+ I +R AG+ADK
Sbjct: 100 DASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKN 159
Query: 150 GGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPL 209
G+TI + +T EP+GVCGQIIPWNFP++M++WK+ PAL GNT++LKPA T L
Sbjct: 160 HGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSL 219
Query: 210 NALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQ 269
AL+ A L KEAG P GVVN+VPG G + G + NH + K+AFTGSTD+G+ + + +
Sbjct: 220 TALYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGN 278
Query: 270 SNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLL 329
+NLK+VTLELGGKS +++ D ++ + G+F N GQ C +GSR +V+D IYD+ +
Sbjct: 279 TNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFV 338
Query: 330 SEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERV-GNK 388
E + VG+PFD + Q N+ Q E IL I GKK+GA ++ GG R G
Sbjct: 339 -ERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLP 397
Query: 389 GYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENIS 448
GYF++PTVF +V++DM I +EEIFGPV + +F +DE + AN+SE+GL A + T+++
Sbjct: 398 GYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLD 457
Query: 449 VALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
A + L+AGTVW+NTYN A PFGGYK SG+GRE GE A +YT++K+V +K+
Sbjct: 458 KANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKV 515
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 425 bits (1092), Expect = e-119
Identities = 216/475 (45%), Positives = 306/475 (63%), Gaps = 4/475 (0%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWSTMDP 92
+FINN++ + KT NPST E+I +V + F S W MD
Sbjct: 39 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDA 98
Query: 93 KKRGSLLFKLADLIEAQKELIASIESADNGKTLALAR-GDVGLVIDYIRSAAGYADKLGG 151
RG LL +LADLIE + +A++E+ DNGK ++ D+ +V+ +R AG+ADK G
Sbjct: 99 SHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHG 158
Query: 152 RTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNA 211
+TI + ++T EP+GVCGQIIPWNFPL+M +WK+ PAL GN V++K A TPL A
Sbjct: 159 KTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 218
Query: 212 LFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSN 271
L+ A+L KEAG P GVVNIVPG G + G I +H + K+AFTGST+IGR + + A SN
Sbjct: 219 LYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSN 278
Query: 272 LKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSE 331
LK+VTLELGGKS +++ DA++ + +F N GQ C +GSR +VQ+ IYD+ +
Sbjct: 279 LKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVER 338
Query: 332 FKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYF 391
++ + VG+PFD Q ++ QF+ IL YI+ GK+EGA +L GG ++GYF
Sbjct: 339 SVARAKSRV-VGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYF 397
Query: 392 IKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVAL 451
I+PTVF +V++ M I KEEIFGPV+ I KF T++E V AN+S +GL A + T+++ A
Sbjct: 398 IQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKAN 457
Query: 452 KVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
+++ L+AGTVW+N Y+ F A PFGGYK SG GRE+GE ++YT++K V +K+
Sbjct: 458 YLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKV 512
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 425 bits (1092), Expect = e-119
Identities = 223/490 (45%), Positives = 314/490 (63%), Gaps = 4/490 (0%)
Query: 19 VSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXX 78
+S+ + + + T LFINN+F+ S GKT NP+T + IV+V
Sbjct: 171 ISLNMADPNAKPKYTKLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKA 230
Query: 79 XXXXFN--SEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVI 136
F+ SEW + P +R +L+ KL L++ K +AS+E+ DNGK A A DV I
Sbjct: 231 AKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSI 290
Query: 137 DYIRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAG 196
++ AG+ DK G TI G G+ + T KEP+GV GQIIPWN+PL+ML+WK PAL G
Sbjct: 291 LTLQYYAGWTDKFFGDTIPAG-GFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVG 349
Query: 197 NTVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGS 256
T+I+KPA TPL AL A+L KEAG PAGV+N+V G G + G I+ HP I K+AFTGS
Sbjct: 350 CTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGS 409
Query: 257 TDIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGS 316
+IGR V AA SNLK+V+LELGGKS +VF+DA+I + +F N GQ C +GS
Sbjct: 410 VEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGS 469
Query: 317 RIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGA 376
R YV + IYD+ +++ + KVG+PF+++ Q + +L YI+ GKKEGA
Sbjct: 470 RTYVHEKIYDEFVAKAAAKAKAR-KVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGA 528
Query: 377 SILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEF 436
+ GG+R+GN G+F++PTVF +VK+DMRI +EEIFGPV +I KFS+++E + AN+ ++
Sbjct: 529 KLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQY 588
Query: 437 GLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
GL AG+ T +I+ ALK A + AG+VWIN Y+ + PFGGYK SG GRE+G++ ++Y
Sbjct: 589 GLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNY 648
Query: 497 TQIKAVRIKL 506
+ K + +KL
Sbjct: 649 LETKTITMKL 658
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 422 bits (1084), Expect = e-118
Identities = 221/475 (46%), Positives = 299/475 (62%), Gaps = 4/475 (0%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWSTMDP 92
LFINN++ + KT NP+T E+I V F S W MD
Sbjct: 39 LFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDA 98
Query: 93 KKRGSLLFKLADLIEAQKELIASIESADNGKTLALARG-DVGLVIDYIRSAAGYADKLGG 151
+RG LL LADL+E + +AS+E+ DNGK + D+ VI R AG+ADK G
Sbjct: 99 SERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHG 158
Query: 152 RTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNA 211
+TI + FT EP+GVCGQIIPWNFPL+M WK+APAL GNTV++K A TPL+A
Sbjct: 159 KTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSA 218
Query: 212 LFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSN 271
L+ ASL KEAG P GVVNI+ G G + G I H + K+AFTGST++G + A SN
Sbjct: 219 LYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSN 278
Query: 272 LKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSE 331
LK+VTLELGGKS +V DA+++ + +F N GQ C +GSR +V+++IY++ L E
Sbjct: 279 LKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFL-E 337
Query: 332 FKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYF 391
+ KVG+PF+ Q +K QFE +L YI +G+KEGA +L GGER G +G+F
Sbjct: 338 RTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFF 397
Query: 392 IKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVAL 451
IKPTVF V++DMRI KEEIFGPV + KF ++E V AN++ +GL A + T ++ A+
Sbjct: 398 IKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAM 457
Query: 452 KVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
+ L+AGTVW+NTYN PFGG+K+SG GRE+GE+ ++YT++K V IK+
Sbjct: 458 YFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKV 512
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 420 bits (1080), Expect = e-117
Identities = 215/475 (45%), Positives = 305/475 (63%), Gaps = 4/475 (0%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN--SEWSTMDP 92
+FINN++ + KT NPST E+I +V + F S W MD
Sbjct: 38 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAREGRPGAFQLGSPWRRMDA 97
Query: 93 KKRGSLLFKLADLIEAQKELIASIESADNGKTLALAR-GDVGLVIDYIRSAAGYADKLGG 151
G LL +LADLIE + +A++E+ DNGK ++ D+ +V+ +R AG+ADK G
Sbjct: 98 SHSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHG 157
Query: 152 RTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNA 211
+TI + ++T EP+GVCGQIIPWNFPL+M +WK+ PAL GN V++K A TPL A
Sbjct: 158 KTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 217
Query: 212 LFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSN 271
L+ A+L KEAG P GVVNIVPG G + G I +H + K+AFTGST+IGR + + A SN
Sbjct: 218 LYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSN 277
Query: 272 LKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSE 331
LK+VTLELGGKS +++ DA++ + +F N GQ C +GSR +VQ+ IYD+ +
Sbjct: 278 LKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVVR 337
Query: 332 FKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYF 391
++ + VG+PFD Q ++ QF+ IL YI+ GK+EGA +L GG ++GYF
Sbjct: 338 SVARAKSRV-VGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYF 396
Query: 392 IKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVAL 451
I+PTVF +V++ M I KEEIFGPV+ I KF T++E V AN+S +GL A + T+++ A
Sbjct: 397 IQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKAN 456
Query: 452 KVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
+++ L+AGTVW+N Y+ F A PFGGYK SG GRE+GE ++YT++K V +K+
Sbjct: 457 YLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKV 511
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 407 bits (1046), Expect = e-113
Identities = 212/472 (44%), Positives = 292/472 (60%), Gaps = 3/472 (0%)
Query: 33 TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNS-EWSTMD 91
T L IN F+ S GKT +P T E+I V ++ F+ W M
Sbjct: 58 TQLLINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVKAARTAFDEGPWPKMS 117
Query: 92 PKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVIDYIRSAAGYADKLG 150
+R +L + ADL+E E +AS+E+ DNGK + ++ + R AG+ADK+
Sbjct: 118 AYERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWADKIH 177
Query: 151 GRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLN 210
G TI Y T EP+GV GQIIPWNFPL+M +WK+ PAL GNT++LK A TPL
Sbjct: 178 GLTIPADGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLT 237
Query: 211 ALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQS 270
A + L EAG+P GV+NIV G G + G + +H + K+AFTGSTD G+ + AA S
Sbjct: 238 AFYAGKLFLEAGLPPGVLNIVSGFGATAGAALASHMDVDKLAFTGSTDTGKVILGLAANS 297
Query: 271 NLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLS 330
NLK VTLELGGKS +VFEDA+I K + +F N GQ C +GSR +V + +YD+ +
Sbjct: 298 NLKPVTLELGGKSPFIVFEDADIDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYDEFVE 357
Query: 331 EFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGY 390
+ K + VG PF + Q + QFE ++ YI G + A++ GG+++G+KGY
Sbjct: 358 KSKARALKRV-VGDPFRKGIEQGPQIDLKQFEKVMKYIKSGIESNATLECGGDQIGDKGY 416
Query: 391 FIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVA 450
FI+PTVF NVK+DM I ++EIFGPV +I KFS VDE + AN++++GL AG+ T+N+ A
Sbjct: 417 FIQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRANETKYGLAAGVFTKNLDTA 476
Query: 451 LKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+V++ LKAGTVW+N ++ FDAA+PFGGYK SG GRE G + +Y QIKAV
Sbjct: 477 NRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQIKAV 528
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 405 bits (1042), Expect = e-113
Identities = 218/488 (44%), Positives = 304/488 (61%), Gaps = 8/488 (1%)
Query: 27 LTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSE 86
++ +QP GLFINN+F S DGKT++ NP+T E I Q+A + F++
Sbjct: 15 ISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNV 74
Query: 87 WSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTL-ALARGDVGLVIDYIRSAAGY 145
WS ++RG L L LIE +++ +A++E+ D GK + A+GD+ ++ R AG
Sbjct: 75 WSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGS 134
Query: 146 ADKLG-GRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPA 204
ADK G TI +T K P GV QI+PWN+PL M WK+ AL AGNTVI+KPA
Sbjct: 135 ADKFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPA 194
Query: 205 SPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVA 264
T L+ L+FA+L K+AG P GVVNIVPG G VG + +H I KI+FTGST +G V
Sbjct: 195 ENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVL 254
Query: 265 IKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTI 324
+ QSNLK VTLE GGKS LVFEDA++ K I + GIF N+GQ C++ SR+YVQ +I
Sbjct: 255 EASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSI 314
Query: 325 YDQLLSEFKTYLETEIKVG---SPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTG 381
YD+ + +FK + E V PFDE + + Q++ I +YI+ GK+E +
Sbjct: 315 YDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQ 374
Query: 382 GERV---GNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGL 438
G KGYFI PT+F +V + +++++EIFGPVV +SKF+ D+A+ LAND+ +GL
Sbjct: 375 TSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGL 434
Query: 439 GAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQ 498
+ + T+++ A A+ +KAGTVWIN+ ND D VPFGG+K SG GRE+G+ ++Y Q
Sbjct: 435 ASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQ 494
Query: 499 IKAVRIKL 506
KAV I L
Sbjct: 495 TKAVHINL 502
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 399 bits (1025), Expect = e-111
Identities = 215/488 (44%), Positives = 302/488 (61%), Gaps = 8/488 (1%)
Query: 27 LTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSE 86
++ +QP GLFINN+F S DGKT++ NP+T E I Q+A + F++
Sbjct: 15 ISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNV 74
Query: 87 WSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTL-ALARGDVGLVIDYIRSAAGY 145
WS ++RG L L LIE +++ +A++E+ D GK + A+ D+ +I+ R AG
Sbjct: 75 WSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGA 134
Query: 146 ADKLG-GRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPA 204
DK G TI +T K P GV QI+PWN+PL M K+ AL AGNTVI+KPA
Sbjct: 135 VDKFNMGETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPA 194
Query: 205 SPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVA 264
T L+ L+FA+L K+AG P GVVN++PG G VG + H I KI+FTGST +G V
Sbjct: 195 ENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVL 254
Query: 265 IKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTI 324
+ QSNLK +TLE GGKS LVFEDA++ K I + NGIF N+GQIC++ SR+YVQ +I
Sbjct: 255 EASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSI 314
Query: 325 YDQLLSEFKTYLETEIKVG---SPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTG 381
YD+ + +FK + E V PFDE + + Q++ I +YI+ GKKE +
Sbjct: 315 YDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQ 374
Query: 382 GERV---GNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGL 438
G KGYFI PT+F +V E +++++EIFGPVV +SKF+ D+A+ LAND+ +GL
Sbjct: 375 TSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGL 434
Query: 439 GAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQ 498
+ + T+++ A A+ +KAGTVWIN N +A VPFGG+K SG GRE G+ ++Y Q
Sbjct: 435 ASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQ 494
Query: 499 IKAVRIKL 506
IK+V + L
Sbjct: 495 IKSVHVDL 502
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 398 bits (1023), Expect = e-111
Identities = 207/486 (42%), Positives = 303/486 (61%), Gaps = 9/486 (1%)
Query: 25 NGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXF- 83
N T + P LFI +F+ ++ KT + NP+ +I +V A F
Sbjct: 414 NKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE 473
Query: 84 NSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVIDYIRSA 142
N W + + RG L+++LADL+E +E +A+IE+ D G LA + VG+ I R
Sbjct: 474 NGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYF 533
Query: 143 AGYADKLGGRTINTGDGYAN----FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNT 198
AG+ DK+ G TI N T KEP+GVCG IIPWN+PLMMLSWK A L AGNT
Sbjct: 534 AGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNT 593
Query: 199 VILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTD 258
V++KPA TPL AL FA L +AGIP GVVN++PG G VG +++HP +RKI FTGST+
Sbjct: 594 VVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTE 653
Query: 259 IGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRI 318
+G+ + A SN+KKV+LELGGKS ++F D ++ K + ++ +F N G+ C + R+
Sbjct: 654 VGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRL 713
Query: 319 YVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASI 378
+V+D+I+D+ + + ++KVG+P D N+ A ++ Y G KEGA++
Sbjct: 714 FVEDSIHDEFVRRVVEEVR-KMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATL 772
Query: 379 LTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFS--TVDEAVALANDSEF 436
+ GG +V G+F +PTVF +V++ M I KEE FGPV+ IS+F+ +D ++ AN +EF
Sbjct: 773 VCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEF 832
Query: 437 GLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
GL +G+ T +I+ AL V+ +L+AGTV++NTYN D A PFGG+KQSG+G+++GE A Y
Sbjct: 833 GLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEY 892
Query: 497 TQIKAV 502
++K V
Sbjct: 893 LRVKTV 898
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 397 bits (1020), Expect = e-110
Identities = 204/473 (43%), Positives = 297/473 (62%), Gaps = 9/473 (1%)
Query: 25 NGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXF- 83
N + + P FIN QF + DGKT NP+ I +V A+ F
Sbjct: 435 NEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFE 494
Query: 84 NSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVIDYIRSA 142
N EW M+ ++RG L+++LADL+E +E +A+IE+ D+G LA + +G+ + R
Sbjct: 495 NGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYF 554
Query: 143 AGYADKLGGRTINTGDGYAN----FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNT 198
AG+ DK+ G TI N FT KEPLGVC IIPWN+PLMML+WK A L AGNT
Sbjct: 555 AGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNT 614
Query: 199 VILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTD 258
++LKPA TPL AL FA L +AG P GV+NI+PG G G ++ HP IRK+ FTGST
Sbjct: 615 LVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTP 674
Query: 259 IGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRI 318
IG+ + A SNLKKV+LELGGKS ++F D + K + + +F N G+ C + R+
Sbjct: 675 IGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRL 734
Query: 319 YVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASI 378
+V+++I+D+ ++ ++ ++K+G P D S N+KA E +L Y + G KEGA++
Sbjct: 735 FVEESIHDEFVTRVVEEIK-KMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATL 793
Query: 379 LTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFST--VDEAVALANDSEF 436
+ GG +V G+F++PTVF +V++ M + KEE FGP++ ISKF +D + AN +E+
Sbjct: 794 VYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEY 853
Query: 437 GLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMG 489
GL +G+ T +I+ A+ V+++L+AGTV+INTYN D A PFGG KQSG+G+++G
Sbjct: 854 GLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLG 906
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 397 bits (1019), Expect = e-110
Identities = 212/473 (44%), Positives = 295/473 (61%), Gaps = 5/473 (1%)
Query: 33 TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNS-EWSTMD 91
T L I +F+ + GKT +P E+I +V ++ F+ W M
Sbjct: 28 TQLLIGGRFVDAVSGKTFPTLDPRNGEVIAQVSEGDAEDVNRAVAAARKAFDEGPWPKMT 87
Query: 92 PKKRGSLLFKLADLIEAQKELIASIESADNGKTLAL-ARGDVGLVIDYIRSAAGYADKLG 150
+R +LF+ ADLIE + IA++E+ DNGK A+ +V ++ R AG+ADK+
Sbjct: 88 AYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAQIEVPMLARVFRYYAGWADKIH 147
Query: 151 GRTINTGDGYANF-TYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPL 209
G T+ GDG + T EP+GV GQIIPWNFPL+MLSWK+ PAL GNTV+LK A TPL
Sbjct: 148 GMTM-PGDGPHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPL 206
Query: 210 NALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQ 269
+AL L EAG+P GVVNIV G G + G I +H + K+AFTGSTD+G+ + A++
Sbjct: 207 SALLVGKLLHEAGLPDGVVNIVSGFGATAGAAIASHMDVDKVAFTGSTDVGKIILELASK 266
Query: 270 SNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLL 329
SNLK VTLELGGKS +V EDA++ + + +F N GQ C +GSR +V + +YD+ +
Sbjct: 267 SNLKAVTLELGGKSPFIVCEDADVDQAVELAHFALFFNQGQCCCAGSRTFVHERVYDEFV 326
Query: 330 SEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG 389
+ K + VG PF Q + QF IL YI G + GA++ GG+R+G+KG
Sbjct: 327 EKAKA-RALKRNVGDPFKSGIEQGPQVDSEQFNKILKYIKHGVEAGATLQAGGDRLGSKG 385
Query: 390 YFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISV 449
Y+I+PTVF +VK+DM I +EIFGPV TI KF +DE +A AN+S +GL AG+ T+N+
Sbjct: 386 YYIQPTVFSDVKDDMLIATDEIFGPVQTILKFKDLDEVIARANNSRYGLAAGVFTQNLDT 445
Query: 450 ALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
A ++ + L+ GTVWIN ++ DA++PFGGYK SG GRE G + +Y Q+KAV
Sbjct: 446 AHRLMRALRVGTVWINCFDVLDASIPFGGYKMSGIGREKGIYSLNNYLQVKAV 498
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 395 bits (1016), Expect = e-110
Identities = 205/486 (42%), Positives = 303/486 (62%), Gaps = 9/486 (1%)
Query: 25 NGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXF- 83
N T + P LFI +F+ ++ KT + NP+ +I +V A F
Sbjct: 414 NKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKGAFE 473
Query: 84 NSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVIDYIRSA 142
N W + + RG L+++LADL+E +E +A+IE+ D G LA + VG+ I R
Sbjct: 474 NGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYF 533
Query: 143 AGYADKLGGRTINTGDGYAN----FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNT 198
AG+ DK+ G TI N T KEP+GVCG IIPWN+PLMMLSWK A L AGNT
Sbjct: 534 AGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNT 593
Query: 199 VILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTD 258
V++KPA TPL AL FA L +AGIP GVVN++PG G VG +++HP +RKI FTGST+
Sbjct: 594 VVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTE 653
Query: 259 IGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRI 318
+G+ + A SN+KKV+LELGG+S ++F D ++ K + ++ +F + G+ C + R+
Sbjct: 654 VGKHIMKSCAISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAAGRL 713
Query: 319 YVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASI 378
+V+D+I+D+ + + ++KVG+P D N+ A ++ Y G KEGA++
Sbjct: 714 FVEDSIHDEFVRRVVEEVR-KMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATL 772
Query: 379 LTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFS--TVDEAVALANDSEF 436
+ GG +V G+F +PTVF +V++ M I KEE FGPV+ IS+F+ +D ++ AN +EF
Sbjct: 773 VCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEF 832
Query: 437 GLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
GL +G+ T +I+ AL V+ +L+AGTV++NTYN D A PFGG+KQSG+G+++GE A Y
Sbjct: 833 GLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEY 892
Query: 497 TQIKAV 502
++K V
Sbjct: 893 LRVKTV 898
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 343 bits (879), Expect = 5e-94
Identities = 188/493 (38%), Positives = 280/493 (56%), Gaps = 38/493 (7%)
Query: 25 NGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN 84
N + + P FI+ +F+ S DG+T K NP+TE+ I E+ AT F
Sbjct: 420 NNMELKFPHDQFIDGKFVGSSDGRTFKTINPATEKPICELPLATVADVDRAVRAAKKAFE 479
Query: 85 -SEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVIDYIRSA 142
EW M ++RG L+KLA+L+E KE +A++ES D G LA + VG+ ID R
Sbjct: 480 RGEWRQMSARERGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTHVGMSIDVWRYF 539
Query: 143 AGYADKLGGRTINTGDGYAN----FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNT 198
AG+ DK+ G+TI + N T +EP+GV G I PWN+PLMMLSWK+A L A
Sbjct: 540 AGWCDKIQGKTIPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKMAACLAAAKI 599
Query: 199 VILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTD 258
+++ + GV+NIV G G VG+ +T HP +RKI FTGST+
Sbjct: 600 KLIEIS---------------------GVINIVTGSGSLVGNRLTAHPDVRKIGFTGSTE 638
Query: 259 IGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRI 318
IG V A+SN+KKV+LELGGKS ++F DA+++K + +F N G+ C + R+
Sbjct: 639 IGATVMESCAKSNIKKVSLELGGKSPLIIFADADLEKAVKQACGAVFFNKGENCIAAGRV 698
Query: 319 YVQDTIYD----QLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKE 374
++ +I+D +L+ E K Y ++G P D S N+ A ++ Y++
Sbjct: 699 FIAKSIHDDFVKKLVEEAKQY-----QIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAG 753
Query: 375 GASILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKF--STVDEAVALAN 432
GA + GG+R+ +G + PT+ N+ ++ EE FGP++ +S F +++ + AN
Sbjct: 754 GAKVEVGGKRLEREGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRAN 813
Query: 433 DSEFGLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEA 492
D+EFGL AG+ T + S +L+VA+ L AGTV++NTY D A PFGG+KQSG+G++MGEEA
Sbjct: 814 DTEFGLAAGVFTRDSSKSLRVAEALHAGTVFVNTYQKTDVAAPFGGFKQSGFGKDMGEEA 873
Query: 493 FESYTQIKAVRIK 505
Y K + I+
Sbjct: 874 LNEYLVTKTITIE 886
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 319 bits (818), Expect = 5e-87
Identities = 179/478 (37%), Positives = 266/478 (55%), Gaps = 12/478 (2%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN----SEWSTM 90
LFI Q+ + KTL V NP+TE+II + +ATS+ F +W+
Sbjct: 10 LFIGGQWTEPVLRKTLPVVNPATEDIIGYIPAATSEDVELAVEAARKAFTRNNGKDWARA 69
Query: 91 DPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLG 150
R L +A + +K +A++E+ D GK L A D+ V A A+ L
Sbjct: 70 TGAVRAKYLRAIAAKVIERKSELANLEAIDCGKPLDEAAWDMDDVAGCFEYYADLAEGLD 129
Query: 151 GRTINT----GDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASP 206
+ D + + KEP+GV G I PWN+PL+M WK+AP+L AG T ILKP+
Sbjct: 130 AKQKTPLSLPMDTFKGYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPSEL 189
Query: 207 TPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIK 266
L L A +C+E G+P GV+NI+ G G G + +HP + KI FTGST G +
Sbjct: 190 ASLTCLELADICREVGLPPGVLNILTGLGTEAGAPLASHPHVDKIVFTGSTTTGSSIMTS 249
Query: 267 AAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYD 326
AA+ +K V+LELGGKS +VF+D +I K + + G F GQICS+ SR+ V + I D
Sbjct: 250 AAKL-VKPVSLELGGKSPIIVFDDVDIDKAVEWTMFGCFWTNGQICSATSRLLVHERIAD 308
Query: 327 QLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVG 386
+ L + + + IK+ PF+E + +K Q+E +L ++ + EGA++L GG R
Sbjct: 309 EFLDKLVKWTK-NIKISDPFEEGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGGVRPE 367
Query: 387 N--KGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIET 444
+ KGYF++P + NV M I +EE+FGP + + FST DEA+ LANDS++GL + +
Sbjct: 368 HLKKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQYGLAGAVLS 427
Query: 445 ENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
++ +V+K +AG VW+N P+GG K+SG+GRE+GE E+Y +K V
Sbjct: 428 NDLERCDRVSKAFQAGIVWVNCSQPCFCQAPWGGTKRSGFGRELGEWGLENYLSVKQV 485
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 308 bits (790), Expect = 1e-83
Identities = 172/488 (35%), Positives = 265/488 (54%), Gaps = 18/488 (3%)
Query: 33 TGLFINNQFIKSQDGK--------TLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFN 84
TG F+ +Q + + G T K P+T +I + + F
Sbjct: 3 TGTFVVSQPLNYRGGAAGAGGRSGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFK 62
Query: 85 SEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAG 144
WS +R +L + A +I +++ IA++E +NGK++ AR D+ + + AG
Sbjct: 63 I-WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAG 121
Query: 145 YADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPA 204
A + G I G +T +EPLGVC I WN+P + SWK APAL GN ++ KP+
Sbjct: 122 LAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPS 181
Query: 205 SPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVA 264
TP++AL A + EAG+P G+ N+V G G + G + HP + K++FTGS G +
Sbjct: 182 PFTPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIM 240
Query: 265 IKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTI 324
+A+ +K VTLELGGKS ++F D ++ + + F GQ+C +G+R++VQ I
Sbjct: 241 EMSAKG-IKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEI 299
Query: 325 YDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGER 384
D+ E + IK+G P E + N+ E +L ++ + K++GA +L GG+
Sbjct: 300 LDKFTEEVVKQTQ-RIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDI 358
Query: 385 VGNK------GYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGL 438
+ GY+++P V N ++DM VKEEIFGPV++I F T E + AND+ FGL
Sbjct: 359 YVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGL 418
Query: 439 GAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQ 498
AG+ T +I A +V L+AGT +IN YN +PFGGYK+SG+GRE G E Y+Q
Sbjct: 419 AAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQ 478
Query: 499 IKAVRIKL 506
+K V +++
Sbjct: 479 LKTVCVEM 486
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 298 bits (763), Expect = 1e-80
Identities = 172/501 (34%), Positives = 275/501 (54%), Gaps = 15/501 (2%)
Query: 9 LNLKIVEQDAVSITLPNGLTYQQPTGLFINNQFIKSQD--GKTLKVENPSTEEIIVEVQS 66
++L +++ D +S LFI+ +F+ + K + + NP+TEEII +
Sbjct: 3 IDLNVIQSDIISARRA------PENSLFIDGKFVSPIEPAAKPIPLINPATEEIIGTCAN 56
Query: 67 ATSQXXXXXXXXXXXXFNSE-WSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTL 125
A+++ F S W+ K+RG +L K+A ++ ++EL+A I++ + GK
Sbjct: 57 ASAKDVDSAVENAYNTFRSGIWAKWPGKQRGLVLRKIAKMMREKRELLAGIDTINCGKPT 116
Query: 126 ALARGDVGLVIDYIRSAAGYADKLGGRT---INTGDGYANFTYKEPLGVCGQIIPWNFPL 182
A D+ D A A+ + G+ F + P GV G I PWNFPL
Sbjct: 117 PYALFDIDSCADMFEYYAEVAETDNPTVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPL 176
Query: 183 MMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTI 242
M WK+ PA+ +GN V+LKP+ P + L FA +CKEAG+P GV+N++ G G+ G +
Sbjct: 177 KMALWKLVPAIASGNCVVLKPSELAPWSCLEFALICKEAGLPDGVLNVIIGSGKESGAAL 236
Query: 243 TNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVN 302
+ HPKI +AFTGS G+ + + AA N+ +TLELGGKS ++ EDA++ IP+
Sbjct: 237 SCHPKIAYLAFTGSLATGKKI-MHAAAENIVPLTLELGGKSPLIICEDADLSLAIPSAAF 295
Query: 303 GIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFE 362
IF N G+ C++ SR+ V +++ D++L + ++ +G+ D + +K QFE
Sbjct: 296 AIFFNQGEACTAASRLIVHESVADEVLGGLVSE-ANKLIIGNGLDPQVTLGPVVSKTQFE 354
Query: 363 TILNYIDIGKKEGASILTGG-ERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKF 421
I++YI EG + GG R KGYFI PTVF NV+ +I +EEIFGPV+ + F
Sbjct: 355 KIVSYIQSAINEGCKCVVGGLPRSEQKGYFIPPTVFTNVQTHNKIWREEIFGPVLAVKTF 414
Query: 422 STVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQ 481
T +EA+ LANDSE+GLG+G+ + N + ++AG +N Y+ +P+ G+K
Sbjct: 415 HTNEEALELANDSEYGLGSGVFSTNPKTLEFFSNNIEAGMCSLNNYHVVTHELPWIGWKH 474
Query: 482 SGYGREMGEEAFESYTQIKAV 502
SG G + + + Y ++K +
Sbjct: 475 SGLGVGLSKHGYNEYMRLKQI 495
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 298 bits (762), Expect = 2e-80
Identities = 174/467 (37%), Positives = 259/467 (55%), Gaps = 24/467 (5%)
Query: 54 NPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKRGSLLFKLADLIEAQKELI 113
+PST E+ V ++ F S WS+ P++R +L ++ADL+E E
Sbjct: 29 DPSTGEVYCRVPNSGKDEIEAAVKAAREAFPS-WSSRSPQERSRVLNQVADLLEQSLEEF 87
Query: 114 ASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTINTGD-------GYANFTYK 166
A ES D GKTLALAR +D RS + +T + G ++T +
Sbjct: 88 AQAESKDQGKTLALAR-----TMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVR 142
Query: 167 EPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPAG 226
P+GV G I PWN PL +L+WKIAPA+ AGNTVI KP+ T + A L +AG+P G
Sbjct: 143 APVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPG 202
Query: 227 VVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHL 286
VVNIV G G VG+ + +HP++ I+FTGS + + + + KK++LELGGK+ +
Sbjct: 203 VVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERIT-QLSAPHCKKLSLELGGKNPAI 261
Query: 287 VFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPF 346
+FEDAN+ + IP V F N G+IC SRI+VQ +IY + L F + KVG P
Sbjct: 262 IFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRF-VEATRKWKVGIPS 320
Query: 347 DESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERV--------GNKGYFIKPTVFY 398
D A+ +KA E + +Y+ EGA I GE V GYF+ PTV
Sbjct: 321 DPLVSIGALISKAHLEKVRSYVKRALAEGAQIWC-GEGVDKLSLPARNQAGYFMLPTVIT 379
Query: 399 NVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLK 458
++K++ + EEIFGPV + F + +E + AN+ ++GL A + + N+ +VAK+L+
Sbjct: 380 DIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQ 439
Query: 459 AGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIK 505
+G VW N + + +PFGG K SG GRE +++++ +T+IK + +K
Sbjct: 440 SGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVK 486
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 295 bits (756), Expect = 8e-80
Identities = 170/468 (36%), Positives = 262/468 (55%), Gaps = 6/468 (1%)
Query: 37 INNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKRG 96
I +++ S D KT+KV NP+T EII +V ++ F S WS + +R
Sbjct: 57 IGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSYEAFTS-WSRLTAGERS 115
Query: 97 SLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTI-- 154
+L + DL+ A KE + + + + GK L A G+V +I A A ++ G I
Sbjct: 116 KVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAYGASFIEYYAEEAKRVYGDIIPP 175
Query: 155 NTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFF 214
N D K+P+GV G I PWNFPL M++ K+ PAL +G TV++KP+ TPL AL
Sbjct: 176 NLSDRRL-LVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAA 234
Query: 215 ASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKK 274
A L +AG+P G +N+V G +GD + P++RKI FTGST +G+ + + AA +KK
Sbjct: 235 AELALQAGVPPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKL-MAAAAPTVKK 293
Query: 275 VTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKT 334
V+LELGG + +VF+DA++ + + F+N+GQ C +R+ VQD IYD+ F
Sbjct: 294 VSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSE 353
Query: 335 YLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKP 394
++ +++VG F + Q + N A + + ++ +GA I+ GG+R F +P
Sbjct: 354 AVQ-KLEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGMTFYEP 412
Query: 395 TVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVA 454
TV +V ++M + KEEIFGPV + +F T ++A+ +AND+ GL A I T ++ + +V
Sbjct: 413 TVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSWRVF 472
Query: 455 KRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+ L+ G V +N PFGG KQSG GRE + + Y +IK V
Sbjct: 473 EALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYV 520
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 291 bits (744), Expect = 2e-78
Identities = 182/486 (37%), Positives = 270/486 (55%), Gaps = 21/486 (4%)
Query: 32 PTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMD 91
P FI N+F +S+ K + NPST + +++ T++ F + W
Sbjct: 27 PLTNFIGNEFARSE--KLMDSVNPSTGKPWIKIPDGTAREVDQAVEAAKEAFKT-WKKTT 83
Query: 92 PKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARG-DVGLVIDYIRSAAGYA-DKL 149
++R +LL K+A+LIE + IA +ES D GK + LA+ D+ + R A A L
Sbjct: 84 VQQRSALLNKVANLIEEFNDDIAILESRDQGKPIGLAKVMDIPRCVQNFRDFANAALYSL 143
Query: 150 GGRTI---NTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASP 206
TI TG + N+ +P+GV G I PWN PL +LS+K+APALVAGNTV+ KP+
Sbjct: 144 STSTILEQPTGK-FVNYVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEM 202
Query: 207 TPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIK 266
T + A K G P GVVN+V G G+S G + +H + I+FTGST IG+ +
Sbjct: 203 TSVTAWVLMHAFKLVGFPPGVVNMVIGEGKSAGQRLVDHVDVPLISFTGSTVIGKKIQED 262
Query: 267 AAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYD 326
A+ N KKV+LE+GGK+ +V+ + K I ++ F N G+IC SR++VQ I+
Sbjct: 263 GAKLN-KKVSLEMGGKNPGIVYSNYR-KSDIASIARSSFLNQGEICLCTSRLFVQKPIFA 320
Query: 327 QLLSEFKTYLETEIK--VGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGG-- 382
+ K+Y+E K VG P + A+N+K +E + +YI++ KKEGA IL GG
Sbjct: 321 DFV---KSYVEEAKKFTVGDPTTQVQI-GAMNSKVHYEKVKSYIELAKKEGADILCGGVT 376
Query: 383 --ERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGA 440
+ GYFI PTV + + +++ +EIFGPVV I+ F T +E + AN + +GL A
Sbjct: 377 TIQNGCENGYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVIERANSTPYGLSA 436
Query: 441 GIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIK 500
+ + + L A L+AGTVW NT+ D ++PFGG KQSG GRE ++ Y+ K
Sbjct: 437 TVWSSDSDELLNTANELRAGTVWCNTWLARDLSMPFGGCKQSGNGREGLHDSLHFYSDAK 496
Query: 501 AVRIKL 506
V + +
Sbjct: 497 TVCVNI 502
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 290 bits (742), Expect = 4e-78
Identities = 166/479 (34%), Positives = 253/479 (52%), Gaps = 10/479 (2%)
Query: 36 FINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKR 95
F+N + + +T V P +++ + AT+ S W R
Sbjct: 90 FLNGKRTTIESTETFDVIEPRIGQVVAKCPKATADIVDQYVKAAADA-QSAWGETTALDR 148
Query: 96 GSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADK-LGGRTI 154
G +L K+ADLI E IA E NGK + AR D+ D G A L G ++
Sbjct: 149 GKVLHKVADLIREHAEEIAIWEVKTNGKPIYEARCDIASSADTFDFFGGIATAVLQGDSL 208
Query: 155 NTGDGYAN---FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNA 211
G + +T +EP GV G I WN+P WK+APAL AGN V+ KP+ P +
Sbjct: 209 ELPGGPSQRIAYTRREPYGVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPASP 268
Query: 212 LFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSN 271
+ + AG+P GV N++ G + G + H + K++FTGS G V +AA N
Sbjct: 269 VLLGEILTAAGVPKGVYNVIQGE-QEAGVALCEHNLVAKVSFTGSVASGEAVQRQAATKN 327
Query: 272 LKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSE 331
+K VTLELGGKS ++F+D+++K + + + F N GQ+C++ +R++VQ I
Sbjct: 328 VKPVTLELGGKSEIIIFDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTEA 387
Query: 332 FKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGY- 390
++KVG P E A N+ + IL Y++ K+EG +L GG RV G
Sbjct: 388 IVQEANDKLKVGDPLLEDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRVHPTGVE 447
Query: 391 ---FIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENI 447
+ +P + + ++ R V+EEIFG V+ I F T +E +A AN++ +GL AG+ + N+
Sbjct: 448 GGAYFEPAIITGLSDEARAVREEIFGAVMLILPFETEEEVIARANNTTYGLAAGVFSGNL 507
Query: 448 SVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIKL 506
+ +VA RL+AGTV+INTYND + VPFGG+K SG+GRE + ++TQ KA+ + +
Sbjct: 508 ARGHRVAARLQAGTVFINTYNDTEVNVPFGGFKNSGHGRENCIDTLRAHTQTKAIYVNV 566
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 285 bits (730), Expect = 9e-77
Identities = 169/476 (35%), Positives = 266/476 (55%), Gaps = 6/476 (1%)
Query: 32 PTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMD 91
P +I +++ + GKT VENP E + V + + F S + D
Sbjct: 23 PARSYIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVEETRKAIKVAHEAFLS-YRNSD 81
Query: 92 PKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGG 151
K+R ++L + DLI + +A++ + +NGK L A+G+V +I AG A ++ G
Sbjct: 82 IKERYAILRRWYDLIMENADDLATMMTLENGKALGDAKGEVVYAAKFIDWFAGEALRISG 141
Query: 152 -RTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLN 210
++++ T K+P+GV G I PWNFP M++ K+ AL AG TV+++PA+ TP
Sbjct: 142 DSSMSSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPFT 201
Query: 211 ALFFASLCKEAGIPAGVVNIVPGPGRSV-GDTITNHPKIRKIAFTGSTDIGRDVAIKAAQ 269
AL A L + AG+PAGV+N+V S G +T +P IRK++FTGST++G+ +A K +
Sbjct: 202 ALALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILA-KQSS 260
Query: 270 SNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLL 329
S LKK++LELGG + +VFEDA+++K L+ F+ +GQ C +RIYV ++YD +
Sbjct: 261 STLKKLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAFV 320
Query: 330 SEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG 389
+ T ++ K+G D + ++ + +++ ++G ++TGG+ N G
Sbjct: 321 -DLVTERVSKFKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLG 379
Query: 390 -YFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENIS 448
+ +PTV N K+ M I +EE FGPV + KF T DE VA ANDS GL + +++IS
Sbjct: 380 PMYFEPTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAGYLFSKDIS 439
Query: 449 VALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRI 504
+V + L+ G V NT D PFGG K+SG+GRE + Y IK++ I
Sbjct: 440 RVFRVGEALQVGMVGCNTGLVSDVLSPFGGVKESGFGREGSKYGISEYLDIKSLTI 495
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 285 bits (730), Expect = 9e-77
Identities = 148/364 (40%), Positives = 215/364 (58%), Gaps = 7/364 (1%)
Query: 32 PTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMD 91
PT LFIN +F+ ++ +TL++ NP+ EE++ +V A++ F W +
Sbjct: 428 PTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQIT 487
Query: 92 PKKRGSLLFKLADLIEAQKELIASIESADNGKTLALA-RGDVGLVIDYIRSAAGYADKLG 150
P++RG L+ LADL+E KE +A+IES D+G LA + VG+ I+ R AG+ DK+
Sbjct: 488 PRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQ 547
Query: 151 GRTINTGDGYAN----FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASP 206
G TI N FT KEP+GVCG I PWN+PLMMLSWK+A + AGNT ++KPA
Sbjct: 548 GNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQT 607
Query: 207 TPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIK 266
PL AL FA L AG P GV+N++PG G G + +H +RK+ FTGST IG+ +
Sbjct: 608 CPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKS 667
Query: 267 AAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYD 326
A SNLKK +LELGGKS ++F D ++ K + + ++ +F N G+ C + R++V+D I+D
Sbjct: 668 CADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHD 727
Query: 327 QLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVG 386
+ + L T + +G P D S N+KA F+ +L + G EGA ++ ER G
Sbjct: 728 EFIRRVLKDLRT-MTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVV-YERYG 785
Query: 387 NKGY 390
Y
Sbjct: 786 RYVY 789
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 283 bits (725), Expect = 3e-76
Identities = 156/426 (36%), Positives = 238/426 (55%), Gaps = 16/426 (3%)
Query: 86 EWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGY 145
+W+ +R +L K DL++ IA E NGK +A A+ DV +D +G
Sbjct: 258 QWAKSSWMERSEILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYFYSGI 317
Query: 146 ADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPAS 205
A L G+ + +T + P+GV I WN+P+ SWK APAL GN VI KP+
Sbjct: 318 ASDLLGQHVPLDASRYAYTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSP 377
Query: 206 PTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAI 265
+P+ AL A + K AG+P GV N++ G + D I +H + K++FTGS G+ +
Sbjct: 378 LSPVTALILAEILKSAGLPDGVFNVIQGDAETAQDLI-HHDGVSKVSFTGSIPTGKKIMK 436
Query: 266 KAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIY 325
A N+K VTLELGGKSA +VF+DA+I + + F + GQ+CS+ S++ V ++
Sbjct: 437 ACADRNIKPVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVL 496
Query: 326 DQLLSEFKTYLETEIKVGSPFDE-----SNFQAAINNKAQFETILNYIDIGKKEGASILT 380
+ + + + ++K+G P E S+ A NK + YI EGA+ L
Sbjct: 497 KEFTKKLVDHTQ-KMKIGDPLKEDTQVGSHISAEHRNKVE-----GYISTAIAEGATKLC 550
Query: 381 GGERVG----NKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEF 436
GG+RV G+++ P + + M + +EEIFG V+ I F T DEA+ +AND++
Sbjct: 551 GGDRVAVHGLENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDM 610
Query: 437 GLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
GL AG+ T+++S + +V+++L AG V++NTYND VPFGG +SG+GRE G E Y
Sbjct: 611 GLAAGLVTKDLSRSYRVSEQLNAGNVYVNTYNDVSPLVPFGGVGESGFGRENGTAVLEHY 670
Query: 497 TQIKAV 502
T +K+V
Sbjct: 671 THLKSV 676
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 276 bits (705), Expect = 7e-74
Identities = 158/471 (33%), Positives = 258/471 (54%), Gaps = 7/471 (1%)
Query: 37 INNQFIKSQDGK-TLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNS-EWSTMDPKK 94
++ ++ S + K T +V NP+ +I +V + T + S EW ++ K
Sbjct: 33 VDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKD 92
Query: 95 RGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTI 154
R +LL K LIE + IA I +A++GK + ++G+V ++ A A ++ G +
Sbjct: 93 RSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIV 152
Query: 155 NTGDGYANF-TYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALF 213
+ K+P+GV I PWNFP+ M++ K AL AG TV++KP+ TPL AL
Sbjct: 153 PSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALA 212
Query: 214 FASLCKEAGIPAGVVNIVP-GPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNL 272
A L +AGIP GV+N+V +GD P +R I+FTGST++G+ + + + +
Sbjct: 213 VAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGK-LLFRNSADGI 271
Query: 273 KKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEF 332
K++ LELGG + +VF+ A+I+K + + F+N GQ C S +R +VQD++YD+ + +
Sbjct: 272 KRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQL 331
Query: 333 KTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG-YF 391
K +E +K+G + N+ QF + +++ + + A+I+ GG+ + +KG F
Sbjct: 332 KKRVEA-LKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLF 390
Query: 392 IKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVAL 451
PT+ +V ++ EE+FGPVV+I +F +EAV AND+ GL +EN+
Sbjct: 391 YAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVF 450
Query: 452 KVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+VAKRL+ G V +N A PFGG K+SG GRE + + Y IK +
Sbjct: 451 RVAKRLEVGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 273 bits (699), Expect = 3e-73
Identities = 158/474 (33%), Positives = 256/474 (53%), Gaps = 7/474 (1%)
Query: 36 FINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKR 95
F+ ++I S + KT +V+NP+T EII +V + + F + + +R
Sbjct: 21 FVQGKWISSPNNKTFEVDNPATGEIIGKVADVSVEETKKAISAANEAFKT-YKNFTHVQR 79
Query: 96 GSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTIN 155
LL + A+LI K+ + + + +NGK L+ A +V Y++ A A + G
Sbjct: 80 SQLLERWAELIMENKDDLVKMLTLENGKPLSQAEMEVTTCSGYLKWYAAEAVRTFGDVAP 139
Query: 156 TGDGYANF--TYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALF 213
+ NF + K+P+GV I PWNFP M++ K AL AG T I PA TP L
Sbjct: 140 SSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVCLG 199
Query: 214 FASLCKEAGIPAGVVNIVPGPGRSV-GDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNL 272
L +EAG P GV+N++ S G +T +P +RK++FTGST++G+ + + + S +
Sbjct: 200 LVRLAQEAGFPDGVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGK-ILMGQSASTI 258
Query: 273 KKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEF 332
KKV++ELGG + +VF D I + + + F + GQ+C +R+YV +YD+ +S+
Sbjct: 259 KKVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVSKL 318
Query: 333 KTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGN-KGYF 391
++T IKVG FD S+ + ++ + + +I+ +GA I GG+ + + KGYF
Sbjct: 319 TEKVKT-IKVGDGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISSSKGYF 377
Query: 392 IKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVAL 451
+PTV V +DM + EE FGP+ ++ KF +E + ANDS+ GL + T N+S +
Sbjct: 378 FEPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGYVFTNNLSTMI 437
Query: 452 KVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIK 505
VAK L+ G V N + + FGG KQSG+G+E G + + +K + +K
Sbjct: 438 HVAKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGVQEFMVVKEINLK 491
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 261 bits (666), Expect = 2e-69
Identities = 157/476 (32%), Positives = 254/476 (52%), Gaps = 14/476 (2%)
Query: 36 FINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKR 95
+I+ +++K D + +V +P++ EII V F + +T P++R
Sbjct: 22 YIDGKWVKGTD-EVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETFKTYKNTT-PRER 79
Query: 96 GSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTIN 155
L + +L+ + +A+I + +NGK L A+G++ Y A A +L G TI
Sbjct: 80 AKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFEWYAEEAPRLYGATIQ 139
Query: 156 TGDGYAN-FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFF 214
+ + FT ++P+GVCG I PWNFP M++ K A AL G TV++KP S TPL+AL
Sbjct: 140 PLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAM 199
Query: 215 ASLCKEAGIPAGVVNIVPGPGRS--VGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNL 272
A L ++AG P G N++ + +G T+ PK++K+ FTGST++G+ + +K + S L
Sbjct: 200 AYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGK-ILMKQSSSTL 258
Query: 273 KKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEF 332
KK++ ELGG + +VFEDA++ + + + F+ GQ C +R+YV +I D+ F
Sbjct: 259 KKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDK----F 314
Query: 333 KTYLETEIK---VGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG 389
L +K +G D + N + E + + +GA ++ G R+ G
Sbjct: 315 AKLLAERVKKFVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELG 374
Query: 390 -YFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENIS 448
F P + +V + KEE FGP+ I F T++E V AND+EFGL A + ++N++
Sbjct: 375 PNFYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVN 434
Query: 449 VALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRI 504
V++ L+ G V NT D ++PFGG K+SG+GRE E YT +K + I
Sbjct: 435 TLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTITI 490
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 259 bits (663), Expect = 5e-69
Identities = 157/484 (32%), Positives = 249/484 (51%), Gaps = 40/484 (8%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIV------EVQSATSQXXXXXXXXXXXXFN---- 84
LFI+ ++ + K + + NP+TEE + ++ +AT++ +
Sbjct: 10 LFIDGEWREPILKKRIPIVNPATEEDLYVLDEIGDIPAATTEDVDVAVNAARRALSRNKG 69
Query: 85 SEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDV----GLVIDYIR 140
+W+ R L +A + +K +A +E+ D GK L A D+ G Y
Sbjct: 70 KDWAKAPGAVRAKYLRAIAAKVNERKTDLAKLEALDCGKPLDEAVWDMDDVAGCFEFYAD 129
Query: 141 SAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVI 200
A G K + + ++ K+PLGV G I PWN+PL+M WK+AP+L AG T I
Sbjct: 130 LAEGLDAKQKAPVSLPMESFKSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGCTAI 189
Query: 201 LKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIG 260
LKP+ + L A +C+E G+P GV+N++ G G G + +HP + KIAFTGS G
Sbjct: 190 LKPSELASVTCLELADICREVGLPPGVLNVLTGFGSEAGAPLASHPGVDKIAFTGSFATG 249
Query: 261 RDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYV 320
V AAQ +K V++ELGGKS +VF+D ++ K + G F GQICS+ SR+ V
Sbjct: 250 SKVMTAAAQL-VKPVSMELGGKSPLIVFDDVDLDKAAEWALFGCFWTNGQICSATSRLLV 308
Query: 321 QDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILT 380
++I + + + + IK+ P +E + +K Q
Sbjct: 309 HESIASEFIEKLVKW-SKNIKISDPMEEGCRLGPVVSKGQHL------------------ 349
Query: 381 GGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGA 440
KG+FI+PT+ +V M+I +EE+FGPV+ + F++ DEA+ LANDS +GLGA
Sbjct: 350 ------EKGFFIEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIELANDSHYGLGA 403
Query: 441 GIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIK 500
+ + + ++++ +AG VWIN P+GG K+SG+GRE+GE ++Y +K
Sbjct: 404 AVISNDTERCDRISEAFEAGIVWINCSQPCFTQAPWGGVKRSGFGRELGEWGLDNYLSVK 463
Query: 501 AVRI 504
V +
Sbjct: 464 QVTL 467
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 259 bits (662), Expect = 7e-69
Identities = 151/474 (31%), Positives = 255/474 (52%), Gaps = 8/474 (1%)
Query: 33 TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDP 92
T F+ +++ + T V++P++ + V + F W +
Sbjct: 61 TDSFVGGRWLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAF-CRWREVSA 117
Query: 93 KKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGR 152
K+R SLL K +L+ K+ +A I +A++GK L A G++ ++ + A ++ G
Sbjct: 118 KERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGD 177
Query: 153 TINT-GDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNA 211
I+T K+P+GV I PWNFP M++ K+ AL AG TV++KPA TP +A
Sbjct: 178 IIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSA 237
Query: 212 LFFASLCKEAGIPAGVVNIVPGP---GRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAA 268
L A L +AGIP+GV N++P + VG+ I P + KI+FTGST G+ + + A
Sbjct: 238 LALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGK-ILLHHA 296
Query: 269 QSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQL 328
+++K+V++ELGG + +VF+ AN+ + + + F+N GQ C ++ VQ I+D
Sbjct: 297 ANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAF 356
Query: 329 LSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNK 388
+ F ++ ++VG+ F+E Q + N+ E + ++ +GA+++TGG+R
Sbjct: 357 VKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLG 416
Query: 389 GYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENIS 448
F +PT+ NV +DM EE FGP+ + KF T +EA+A+AN ++ GL +++ +
Sbjct: 417 KNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPA 476
Query: 449 VALKVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+VA++L+ G V +N PFGG KQSG GRE + + Y ++K V
Sbjct: 477 QIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 234 bits (598), Expect = 2e-61
Identities = 139/466 (29%), Positives = 243/466 (51%), Gaps = 6/466 (1%)
Query: 36 FINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKR 95
+I ++ S+ G + V NP E++ + T + F+ T K+R
Sbjct: 21 YIGGKWTASETGNSFDVLNPFNNEVVDRATNCTVKDAEKAVHSALEGFDKWAHTYSAKQR 80
Query: 96 GSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTIN 155
G++L K +++ ++ +A++ + + GK LA ARG++ Y AG A ++ G+ +
Sbjct: 81 GAILHKWFEILVQRETELATLLTKEQGKPLAEARGEIQYSAAYFDWYAGEARRVYGQVVP 140
Query: 156 TGD-GYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFF 214
+ + +EP+GV I PWNFP M++ K A AL G + ++KP+ TPL+AL
Sbjct: 141 SAVVNRLHLHTREPIGVVALIAPWNFPTAMIARKAAAALSVGCSAVVKPSGDTPLSALAL 200
Query: 215 ASLCKEAGIPAGVVNIVPGPGRSVGDT---ITNHPKIRKIAFTGSTDIGRDVAIKAAQSN 271
A +EAGIPAGV N++ + + + + I+FTGST +G+ + ++A S
Sbjct: 201 AQTAEEAGIPAGVFNVITADHSNTAEISKYLCESTDVSAISFTGSTPVGKLLLAQSA-ST 259
Query: 272 LKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSE 331
+K+V LELGG + +VF+DA++ + + F+ +GQ C S +RIYV + I+DQ +S+
Sbjct: 260 VKRVCLELGGNAPLIVFDDADLDVAVNGTMATKFRCSGQTCVSANRIYVHEKIHDQYISK 319
Query: 332 FKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYF 391
++ ++ +G + Q + N+ + + +G+ ++ GG+R G G
Sbjct: 320 LAAAMKEKLVLGDGLNPKTTQGPLVNQKAVDKCELLLSDALGKGSELICGGKR-GEHGTS 378
Query: 392 IKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVAL 451
+PT+ NV+ + I EIFGP+ ++ KF E + AN+ GL + + S
Sbjct: 379 YEPTLITNVQSNTNIAHTEIFGPIASVQKFRDEQEVLEAANNCRVGLAGYVFGRDQSRLQ 438
Query: 452 KVAKRLKAGTVWINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYT 497
+VA++L+ G V +N A FGG K+SG GRE G + + +T
Sbjct: 439 RVARKLEVGMVGVNEGLISCAEAAFGGVKESGIGREGGAQGIDEFT 484
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 223 bits (567), Expect = 7e-58
Identities = 151/478 (31%), Positives = 236/478 (48%), Gaps = 17/478 (3%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKK 94
LFI +F++S+ K + + NP+T E+I V AT F + W+
Sbjct: 42 LFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA-WADTSVLS 100
Query: 95 RGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTI 154
R +L + LI+ + IA + + + GKTLA A GDV + + A + G T+
Sbjct: 101 RQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETM 160
Query: 155 -NTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALF 213
+ ++Y+ PLGVC I P+NFP M+ W A+V GNT ++KP+ P +
Sbjct: 161 PSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATML 220
Query: 214 FASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLK 273
A L +++G P G +NI+ G +V + I +HP I+ I+F GS G + + ++ K
Sbjct: 221 LAKLLQDSGAPDGTLNIIHGQHEAV-NFICDHPDIKAISFVGSNKAGEYIFERGSRHG-K 278
Query: 274 KVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFK 333
+V +G K+ +V DAN + T+ LV F AGQ C + S + L +
Sbjct: 279 RVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVE 338
Query: 334 TYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGY--- 390
+ G ++ I +A+ E + N ID G KEGASIL G ++ KGY
Sbjct: 339 HAKNLRVNAGDQ-PGADLGPLITPQAK-ERVCNLIDSGTKEGASILLDGRKIKVKGYENG 396
Query: 391 -FIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISV 449
F+ PT+ NVK +M KEEIFGPV+ + + T+DEA+ + N++ +G G I T N +
Sbjct: 397 NFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGAT 456
Query: 450 ALKVAKRLKAGTVWINTYNDFDAAVP---FGGYKQS--GYGREMGEEAFESYTQIKAV 502
A K A + G V +N +P F G + S G G++ + YTQ+K +
Sbjct: 457 ARKYAHLVDVGQVGVNV--PIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTI 512
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 211 bits (537), Expect = 2e-54
Identities = 137/459 (29%), Positives = 225/459 (48%), Gaps = 12/459 (2%)
Query: 47 GKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKRGSLLFKLADLI 106
G+ ++ P+ I VQ+ Q +N +W + +RG ++ ++ D +
Sbjct: 36 GQVVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYN-DWCEVPAPRRGEIVRQIGDKL 94
Query: 107 EAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTI-NTGDGYANFTY 165
Q + + + S + GK A G+V +D A G + L G+ + G+A
Sbjct: 95 RTQLQNLGKLVSLEMGKISAEGVGEVQEYVDICDYATGLSRSLEGKIFPSERPGHALLEQ 154
Query: 166 KEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEA---- 221
PLGV G I +NFP + W A ALV GN+V+ KPA TPL A+ L +E
Sbjct: 155 WNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLVEEVLVAN 214
Query: 222 GIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGG 281
+ + ++V G G VG + ++ ++FTGS++IG+ V + Q+ K+ LELGG
Sbjct: 215 NVNPALCSLVCGEG-DVGQALVKDKRVNLVSFTGSSEIGKIVG-QQVQARFGKLLLELGG 272
Query: 282 KSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFK-TYLETEI 340
+A +V EDA++ +P V AGQ C++ R+ V D +YDQ+L K Y + E
Sbjct: 273 NNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLERLKKAYAQFES 332
Query: 341 KVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNV 400
++G P D + ++N+ + G I GG+ + G F+ PT+ +
Sbjct: 333 RIGCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGKIEYGGKVLERDGNFVLPTIVTGL 392
Query: 401 KEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALK--VAKRLK 458
K D +V E F P++ + KFST++EA+A+ N+ + GL + + T NI K K
Sbjct: 393 KHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQGLSSSLFTTNIQNVFKWMGPKGSD 452
Query: 459 AGTVWIN-TYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
G V +N + + FGG K++G GRE G +++ Y
Sbjct: 453 CGIVNVNIPTSGAEIGGAFGGEKETGGGRESGSDSWRQY 491
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 209 bits (532), Expect = 8e-54
Identities = 153/479 (31%), Positives = 238/479 (48%), Gaps = 23/479 (4%)
Query: 37 INNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKRG 96
I F++SQ + V NP+T+E++ +V T++ F W R
Sbjct: 118 IGGSFVESQSSSFIDVINPATQEVVSKVPLTTNEEFKAAVSAAKQAFPL-WRNTPITTRQ 176
Query: 97 SLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYAD-KLGGRTIN 155
++ K +LI + +A + + GKTL + GD+ ++ + A G A ++G N
Sbjct: 177 RVMLKFQELIRKNMDKLAMNITTEQGKTLKDSHGDIFRGLEVVEHACGMATLQMGEYLPN 236
Query: 156 TGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFA 215
+G ++ +EPLGVC I P+NFP M+ W A+ GNT ILKP+ P ++ A
Sbjct: 237 VSNGVDTYSIREPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFILKPSEKDPGASVILA 296
Query: 216 SLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKV 275
L EAG+P GV+NIV G +V + I + IR ++F GS G + +AA K++
Sbjct: 297 ELAMEAGLPDGVLNIVHGTNDTV-NAICDDEDIRAVSFVGSNTAGMHIYARAAAKG-KRI 354
Query: 276 TLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSR-IYVQD--TIYDQLLSEF 332
+G K+ LV DANI T+ L+ F AGQ C + S ++V D + D+L+
Sbjct: 355 QSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCMALSTVVFVGDAKSWEDKLVERA 414
Query: 333 KTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERV----GNK 388
K ++ GS D ++ I+ +A+ E I I G +GA +L G + K
Sbjct: 415 KA---LKVTCGSEPD-ADLGPVISKQAK-ERICRLIQSGVDDGAKLLLDGRDIVVPGYEK 469
Query: 389 GYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENIS 448
G FI PT+ V DM KEEIFGPV+ + ++ DEA+++ N +++G GA I T + +
Sbjct: 470 GNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISIINKNKYGNGAAIFTSSGA 529
Query: 449 VALKVAKRLKAGTVWINTYNDFDAAVP---FGGYKQSGYG--REMGEEAFESYTQIKAV 502
A K ++AG + IN +P F G K S G G+ + +TQIK V
Sbjct: 530 AARKFQMDIEAGQIGINV--PIPVPLPFFSFTGNKASFAGDLNFYGKAGVDFFTQIKTV 586
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 204 bits (518), Expect = 3e-52
Identities = 142/481 (29%), Positives = 229/481 (47%), Gaps = 19/481 (3%)
Query: 33 TGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDP 92
T LFI+ +F++S+ + + V +P+T +++ V AT F S WS
Sbjct: 58 TKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRS-WSNQSI 116
Query: 93 KKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGR 152
R ++FKL LI+ +A + + GKTLA A GDV + + G
Sbjct: 117 LTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGE 176
Query: 153 TI-NTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNA 211
T+ N ++ PLGV + P+NFP M+ W A+ GNT++LKP+ P
Sbjct: 177 TVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGAT 236
Query: 212 LFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSN 271
+ L EAG P GVVN++ G +V + I + P+I+ ++F GS G+ + +A + N
Sbjct: 237 MLLMELLNEAGCPPGVVNVIHGQHDAV-NFICDAPEIKAVSFVGSDQAGKYIYERAGK-N 294
Query: 272 LKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSS-GSRIYVQDTIYDQLLS 330
K+V +G K+ ++ DAN + T+ L F AGQ C + + ++V D Q
Sbjct: 295 GKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDA---QAWI 351
Query: 331 EFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVG---- 386
++KV + + + A + I + I+ G KEGA ++ G ++
Sbjct: 352 PDLVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGY 411
Query: 387 NKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETEN 446
GYF+ PT+ +V M+ EEIFGPV+ I K T+D+A+ + N + +G G + T N
Sbjct: 412 EDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTN 471
Query: 447 ISVALKVAKRLKAGTVWINTYNDFDAAVP---FGGYKQSGYGRE--MGEEAFESYTQIKA 501
+ A K + AG V +N +P F G + S G G++ + YTQ K
Sbjct: 472 GAAARKFVNEIDAGQVGVNV--PIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKT 529
Query: 502 V 502
V
Sbjct: 530 V 530
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 203 bits (516), Expect = 6e-52
Identities = 143/484 (29%), Positives = 229/484 (46%), Gaps = 29/484 (5%)
Query: 35 LFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKK 94
L+I+ Q ++S+ +++ NP+T E+I V +AT FN+ W P
Sbjct: 32 LWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNT-WKNTSPLT 90
Query: 95 RGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTI 154
R +FKL LI+ + +A + + GKTL A GDV + + A + G T+
Sbjct: 91 RQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETL 150
Query: 155 -NTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALF 213
N +Y+ PLGV I P+NFP M+ W AL GNT+++KP+ P A
Sbjct: 151 PNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQL 210
Query: 214 FASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLK 273
L KEAG+P G VNI+ G +V + I ++P I+ I+F G G+ + + A+ N K
Sbjct: 211 LVELAKEAGVPDGCVNIIHGQHSAV-NFICDNPDIKAISFVGGDAAGKHIYERGAK-NGK 268
Query: 274 KVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFK 333
+V +G K+ ++ DAN ++T+ L F AGQ C + + L+ E +
Sbjct: 269 RVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAV--------LVGEAR 320
Query: 334 TYL------ETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGN 387
+L +KV + + + +K +L I+ KKEGA + G +
Sbjct: 321 AWLPELVEKAKNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITV 380
Query: 388 KGY----FIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIE 443
G+ F+ PT+ VK +M +EEIFGPV+ + + ++EA+ + N++ +G G I
Sbjct: 381 PGFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIF 440
Query: 444 TENISVALKVAKRLKAGTVWINTYNDFDAAVP---FGGYKQSGYG--REMGEEAFESYTQ 498
T N + A K + G + IN +P F G + S G G+ + YTQ
Sbjct: 441 TSNGATARKFTNEVDVGQIGINV--PIPVPLPMFSFTGSRGSFLGDLNFYGKAGIQFYTQ 498
Query: 499 IKAV 502
K V
Sbjct: 499 WKTV 502
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 200 bits (509), Expect = 4e-51
Identities = 139/467 (29%), Positives = 222/467 (46%), Gaps = 13/467 (2%)
Query: 47 GKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKRGSLLFKLADLI 106
G ++ +P T + I +V+ Q + +W + RG ++ ++ D +
Sbjct: 115 GPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYK-QWRQVPAPVRGEIVRQIGDEL 173
Query: 107 EAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTINTGDG-YANFTY 165
KE + + S + GK + +G+V ID A G + G+ IN+ ++
Sbjct: 174 RKYKEPLGKLVSLEVGKIYSEGQGEVQEFIDICDYAVGLSRIYSGQLINSERADHSILEA 233
Query: 166 KEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNAL----FFASLCKEA 221
PLGV G I +NFP + W A AL GN+V+ K A TPL ++ A + +
Sbjct: 234 WRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRN 293
Query: 222 GIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGG 281
+P VV + G G VG T+ ++ ++FTGS GRDV ++ Q KV LELGG
Sbjct: 294 NLPP-VVTLCQG-GTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEV-QRRFGKVILELGG 350
Query: 282 KSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFK-TYLETEI 340
+A ++ E AN+K + + G +GQ C++ RI V + ++DQ + E Y +
Sbjct: 351 NNALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLIS 410
Query: 341 KVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNV 400
K+G + ++ + E I K G ++ GG + G++++PTV +
Sbjct: 411 KIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGL 470
Query: 401 KEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALK--VAKRLK 458
D +V E F P+V I K VD+A+ N+ E GL + I TENI A K AK
Sbjct: 471 PHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSD 530
Query: 459 AGTVWIN-TYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRI 504
G V IN T N + FGG K +G GRE G +A++ Y + + +
Sbjct: 531 CGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITV 577
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 198 bits (504), Expect = 1e-50
Identities = 145/490 (29%), Positives = 244/490 (49%), Gaps = 39/490 (7%)
Query: 36 FINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKR 95
+ + ++ S GK++ + NP+T + +VQ+ T + S W+ KR
Sbjct: 19 YADGEWKTSSSGKSVAIMNPATRKTQYKVQACTQEEVNAVMELAKSAQKS-WAKTPLWKR 77
Query: 96 GSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSA--AGYADKLGGRT 153
LL K A +++ K +A +A+ V + +RS Y + G R
Sbjct: 78 AELLHKAAAILKDNKAPMAE------SLVKEIAKPAKDSVTEVVRSGDLISYCAEEGVRI 131
Query: 154 INTG-----DGYAN-------FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVIL 201
+ G D + T K PLGV I P+N+P+ + KIAPAL+AGN+++L
Sbjct: 132 LGEGKFLLSDSFPGNDRTKYCLTSKIPLGVVLAIPPFNYPVNLAVSKIAPALIAGNSLVL 191
Query: 202 KPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGR 261
KP + ++ L AG P G+++ + G G +GD +T HP + I+FTG D G
Sbjct: 192 KPPTQGAVSCLHMVHCFHLAGFPKGLISCITGKGSEIGDFLTMHPAVNCISFTGG-DTGI 250
Query: 262 DVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQ 321
++ KA L+ +ELGGK A +V +DA++ N++ G F +GQ C++ + V
Sbjct: 251 SISKKAGMIPLQ---MELGGKDACIVLDDADLDLVASNIIKGGFSYSGQRCTAVKVVLVM 307
Query: 322 DTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYID----IGKKEGAS 377
+++ D+L+ + K + ++ VG P + S+ A ++ E+ N+I+ K++GA+
Sbjct: 308 ESVADELVEKVKAKV-AKLTVGPPEENSDITAVVS-----ESSANFIEGLVMDAKEKGAT 361
Query: 378 ILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFG 437
+R GN I P + NV+ DMRI EE FGPVV + + ++V+E + N S FG
Sbjct: 362 FCQEYKREGN---LIWPLLLDNVRPDMRIAWEEPFGPVVPVLRINSVEEGINHCNASNFG 418
Query: 438 LGAGIETENISVALKVAKRLKAGTVWINTYNDFDA-AVPFGGYKQSGYGREMGEEAFESY 496
L + T++I+ A+ ++ ++ GTV IN+ PF G K SG G + +
Sbjct: 419 LQGCVFTKDINKAILISDAMETGTVQINSAPARGPDHFPFQGLKDSGIGSQGVTNSINLM 478
Query: 497 TQIKAVRIKL 506
T++K I L
Sbjct: 479 TKVKTTVINL 488
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 195 bits (495), Expect = 2e-49
Identities = 131/459 (28%), Positives = 224/459 (48%), Gaps = 13/459 (2%)
Query: 46 DGKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKRGSLLFKLADL 105
+G + NP+ + I +V A+ + W + KRG ++ ++ D
Sbjct: 32 NGPLVSTLNPANNQPIAQVVEASLEDYEQGLKACEEAAKI-WMQVTAPKRGDIVRQIGDA 90
Query: 106 IEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTI-NTGDGYANFT 164
+ ++ + + + S + GK LA G+V VID A G + +L G I + +
Sbjct: 91 LRSKLDYLGRLLSLEMGKILAEGIGEVQEVIDMCDFAVGLSRQLNGSVIPSERPNHMMLE 150
Query: 165 YKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEA--- 221
PLG+ G I +NFP +L W ALV GN V+ K A TPL + L E
Sbjct: 151 MWNPLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLVAEVLEK 210
Query: 222 -GIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELG 280
+P + + G G +G+ I +I ++FTGS+ +G V + + K LEL
Sbjct: 211 NNLPGAIFTAMCG-GAEIGEAIAKDTRIPLVSFTGSSRVGSMVQ-QTVNARSGKTLLELS 268
Query: 281 GKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEI 340
G +A +V +DA+I+ +++ AGQ C++ R+ + +++YD++L + T + ++
Sbjct: 269 GNNAIIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVLEQLLTSYK-QV 327
Query: 341 KVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNV 400
K+G+P ++ ++ + I++ K +G ILTGG+ V +G F++PT+ +
Sbjct: 328 KIGNPLEKGTLLGPLHTPESKKNFEKGIEVIKSQGGKILTGGKAVEGEGNFVEPTII-EI 386
Query: 401 KEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRL--K 458
D +VKEE+F PV+ + KF + EAVA+ N GL + I T N + L
Sbjct: 387 SADAAVVKEELFAPVLYVLKFKSFGEAVAINNSVPQGLSSSIFTRNPENIFRWIGPLGSD 446
Query: 459 AGTVWIN-TYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
G V +N N + FGG K +G GRE G ++++ Y
Sbjct: 447 CGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQY 485
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 192 bits (488), Expect = 1e-48
Identities = 118/458 (25%), Positives = 227/458 (48%), Gaps = 12/458 (2%)
Query: 47 GKTLKVENPSTEEIIVEVQSATSQXXXXXXXXXXXXFNSEWSTMDPKKRGSLLFKLADLI 106
G+ + P+ E I V+ A+ + W+ + KRG ++ ++ D +
Sbjct: 35 GEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKI-WADIPAPKRGEIVRQIGDAL 93
Query: 107 EAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTI-NTGDGYANFTY 165
+ +++ S+ S + GK L G+V +D A G + +GG + + G+A
Sbjct: 94 REKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQ 153
Query: 166 KEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNAL----FFASLCKEA 221
P+G+ G I +NFP+ + W A A++ GN + K A T L ++ A + ++
Sbjct: 154 WNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDN 213
Query: 222 GIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGG 281
+P + ++ G G +G + ++ ++FTGST +G+ V + Q + LELGG
Sbjct: 214 KLPGAICSLTCG-GADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QERFGRSLLELGG 271
Query: 282 KSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIK 341
+A + FEDA++ +P+ + AGQ C++ R+++ ++I+D++++ K +I+
Sbjct: 272 NNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAY-AQIR 330
Query: 342 VGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVK 401
VG+P+D + ++ K L ++ KKEG +++ GG+ + G +++PT+ +
Sbjct: 331 VGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLG 390
Query: 402 EDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALK--VAKRLKA 459
D I E F P++ + KF +E A N+ + GL + I T+++ + K
Sbjct: 391 HDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDC 450
Query: 460 GTVWIN-TYNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
G V +N + + FGG K +G GRE G +A++ Y
Sbjct: 451 GIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQY 488
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 185 bits (469), Expect = 2e-46
Identities = 139/509 (27%), Positives = 242/509 (47%), Gaps = 24/509 (4%)
Query: 10 NLKIVEQDAVSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATS 69
N+ ++ DA + L +G ++ + ++I + Q K ++ P+T + + A S
Sbjct: 27 NVPSIDVDASDV-LAHGKDTEENSFIYIPPRGRSQQSDKKVQCYEPATMKYLGYFP-ALS 84
Query: 70 QXXXXXXXXXXXXFNSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALAR 129
W+ K R L L I +ELI + S D GKT+ A
Sbjct: 85 PTEVEERVTLSRKAQKTWAQSSFKLRRQFLRILLKYIIEHQELICEVSSRDTGKTMVDAS 144
Query: 130 -GDVGLVIDYIRSAAGYADK-LGGRTINTGDGYANFTYK---EPLGVCGQIIPWNFPLMM 184
G++ + I ++ L + ++G + + PLGV G I+PWN+P
Sbjct: 145 LGEIMTTCEKITWLLSEGERWLKPESRSSGRAMLHKVSRVEFHPLGVIGAIVPWNYPFHN 204
Query: 185 LSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEA----GIPAGVVNIVPGPGRSVGD 240
+ + A+ +GN +++K + + F+ + + A G P +V+++ G + G+
Sbjct: 205 IFNPMLAAVFSGNGIVIKVSEHASWSGCFYFRIIQAALAAVGAPENLVDVITGFAET-GE 263
Query: 241 TITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNL 300
+ + + K+ F GST +G+ + AA++ L VTLELGGK A ++ EDA++
Sbjct: 264 ALVS--SVDKMIFVGSTAVGKMIMRNAAET-LTPVTLELGGKDAFIICEDADVSHVAQVA 320
Query: 301 VNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQ 360
V G +++GQ C+ R YV IY + + T + + G P AI +
Sbjct: 321 VRGTLQSSGQNCAGAERFYVHKDIYTAFIGQV-TKIVKSVSAGPPLTGRYDMGAICLQEH 379
Query: 361 FETILNYIDIGKKEGASILTGGERVGNKG-----YFIKPTVFYNVKEDMRIVKEEIFGPV 415
E + + ++ +GA I G G+ G + PTV NV +M+I+KEE FGP+
Sbjct: 380 SEHLQSLVNDALDKGAEIAVRGS-FGHLGEDAVDQYFPPTVLINVNHNMKIMKEEAFGPI 438
Query: 416 VTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWINTY--NDFDAA 473
+ I +FST +E + LANDS + LG + + + A ++A +++ G IN + N +
Sbjct: 439 MPIMQFSTDEEVIKLANDSRYALGCAVFSGSKHRAKQIASQIQCGVAAINDFASNYMCQS 498
Query: 474 VPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+PFGG K SG+GR G E + +K+V
Sbjct: 499 LPFGGVKDSGFGRFAGIEGLRACCLVKSV 527
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 173 bits (439), Expect = 5e-43
Identities = 132/447 (29%), Positives = 209/447 (46%), Gaps = 34/447 (7%)
Query: 85 SEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKT-LALARGDVGLVIDYIRSAA 143
S W D +R +L L D I ++LIA + D+GKT L + G++ + ++ I+
Sbjct: 146 STWGNSDFSRRLRVLASLHDYILNNQDLIARVACRDSGKTMLDASMGEILVTLEKIQ--- 202
Query: 144 GYADKLGGRTINTG--DGYANFTYK---------EPLGVCGQIIPWNFPLMMLSWKIAPA 192
+ K G R + G NF K EPLGV I+ WN+P L I A
Sbjct: 203 -WTIKHGQRALQPSRRPGPTNFFMKWYKGAEIRYEPLGVISSIVSWNYPFHNLLGPIIAA 261
Query: 193 LVAGNTVILKPASPTPLNALFFASL---CKEA-----GIPAGVVNIVPGPGRSVGDTITN 244
L GN +++K + ++ FF L C EA + + P + T+
Sbjct: 262 LFTGNAIVVKCSEQVVWSSEFFVELIRKCLEACDEDPDLVQLCYCLPPTENDDSANYFTS 321
Query: 245 HPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDA-NIKKTIPNLVNG 303
HP + I F GS + + +K A +L V +ELGGK A +V + A N+ ++ G
Sbjct: 322 HPGFKHITFIGSQPVAHYI-LKCAAKSLTPVVVELGGKDAFIVLDSAKNLDALSSIIMRG 380
Query: 304 IFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETE-IKVGSPFD--ESNFQAAINNKAQ 360
F+++GQ C R+ V YD L+ + ++ GS D E+ A+ + +
Sbjct: 381 TFQSSGQNCIGIERVIVSKENYDDLVKILNDRMTANPLRQGSDIDHLENVDMGAMISDNR 440
Query: 361 FETILNYIDIGKKEGASILTGGERVGN----KGYFIKPTVFYNVKEDMRIVKEEIFGPVV 416
F+ + + +GA +L GG R + +G++ +PT+ +V +M+I + E+FGP++
Sbjct: 441 FDELEALVKDAVAKGARLLQGGSRFKHPKYPQGHYFQPTLLVDVTPEMKIAQNEVFGPIL 500
Query: 417 TISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAA-VP 475
+ K D V LAN + FGLG + +I VA L+ G V IN + F +P
Sbjct: 501 VMMKAKNTDHCVQLANSAPFGLGGSVFGADIKECNYVANSLQTGNVAINDFATFYVCQLP 560
Query: 476 FGGYKQSGYGREMGEEAFESYTQIKAV 502
FGG SGYG+ GEE K+V
Sbjct: 561 FGGINGSGYGKFGGEEGLLGLCNAKSV 587
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 165 bits (418), Expect = 1e-40
Identities = 121/434 (27%), Positives = 207/434 (46%), Gaps = 23/434 (5%)
Query: 86 EWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLA-LARGDVGLVIDYIRSAAG 144
EW + +R + L L + I ++ A I D GKTL A G++ + ++ I
Sbjct: 40 EWKSTSFAERRNFLKALKENIIRNQDKYAEIACKDTGKTLVDAAFGEILVTLEKINWTLA 99
Query: 145 YADKLGGRTINTGD-------GYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGN 197
++ T GY + EPLGV ++ WN+PL I AL AGN
Sbjct: 100 NGEQSLRPTKRPNSLLTSYKGGYVKY---EPLGVIAALVSWNYPLHNALGPIISALFAGN 156
Query: 198 TVILKPASPTPLNALFFA----SLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAF 253
+++K + T + + SL + G +V + V D +T+H I+ I F
Sbjct: 157 AIVVKGSELTAWSTHQYCEMVRSLLQSMGHSPELVQCITCLP-DVADHLTSHSGIKHITF 215
Query: 254 TGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICS 313
GS I + VA AA+ L + LELGGK ++ +D +++ + ++ G+F++AGQ C
Sbjct: 216 IGSQPIAKLVAASAAKQ-LTPLCLELGGKDPCILTDDHRLEEILSIVMRGVFQSAGQNCI 274
Query: 314 SGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKK 373
RI D +YD ++++ + T +++G A+ + +F+ + + I
Sbjct: 275 GIERIIALDGVYDTIITKLYNRIST-MRLGMYTQNDVDMGAMVSNNRFDHLESLIQDAVS 333
Query: 374 EGASILTGGERVGN----KGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVA 429
+GA ++ GG R + KG + PT+ + +M+I +EE F P+ + + + + A+
Sbjct: 334 KGARLVYGGHRFQHPKYPKGNYFLPTLLVDATNEMKIAQEECFAPIALVFRAKSPEHALE 393
Query: 430 LANDSEFGLGAGIETENISVALKVAKRLKAGTVWINTYNDFD-AAVPFGGYKQSGYGREM 488
+AN +EFGLGA + + + L+ G V +N + F +PFGG K+SGYGR
Sbjct: 394 IANGTEFGLGASVFGRDKQLCQYFTDNLETGMVAVNDFGAFYLLQMPFGGCKKSGYGRFA 453
Query: 489 GEEAFESYTQIKAV 502
G E KA+
Sbjct: 454 GYEGLRGICNSKAI 467
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 157 bits (396), Expect = 5e-38
Identities = 123/426 (28%), Positives = 201/426 (46%), Gaps = 27/426 (6%)
Query: 87 WSTMDPKKRGSLLFKLADLIEAQ-KELIASIESADNGKTLALARGDVGL-VIDYIRSAAG 144
W ++ R ++ K A LI + + + + GK + A D G+ +ID++R
Sbjct: 97 WESLPFADRSAIFLKAAHLISTKYRYKLMAATMIGQGKNIWQAEIDAGMEIIDFLRFNTK 156
Query: 145 YADKLGGRTI--NTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILK 202
YA +L NT + Y+ G I P+NF + + AP L+ GN V++K
Sbjct: 157 YASELYASQPPENTPGVWNRMEYRPLEGFVYAITPFNFTAIAGNLAAAPLLM-GNVVLMK 215
Query: 203 PASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGST----- 257
P+ L++ + +EAG+PAG + +PG V NHP+ + FTGST
Sbjct: 216 PSDHAVLSSYIVYQIFREAGLPAGALQFIPGDAVEVSKVCFNHPEFAGLHFTGSTAVFRS 275
Query: 258 ---DIGRDVAIKAAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSS 314
IG +VA K+ E GGK+ HLV A IK + N V F+ GQ CS+
Sbjct: 276 LWGTIGENVA-NGKYRTYPKIVGETGGKNFHLVHSSAEIKSAVVNAVRAAFEYQGQKCSA 334
Query: 315 GSRIYVQDTIYDQLLSEFKTYLETEIKVGSPF-DESNFQAAINNKAQFETILNYIDIGKK 373
SR+YV ++ + T +KVG+P D +NF + ++A F + ++
Sbjct: 335 LSRLYVSKYAWENGFRDELTKQVKSLKVGAPLTDFANFVGPVIHQASFNKLKKVLESAAS 394
Query: 374 EG-ASILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVD-EAVA-- 429
+ +L GG+ ++G+F++PTV + I E+FGPV+++ + + +AV
Sbjct: 395 DSEIEVLAGGKADDSEGFFVEPTVLLSKNPKHDIFVNELFGPVLSVYVYEDDNLDAVCDL 454
Query: 430 LANDSEFGLGAGIETENISVALKVAKRLK--AGTVWINTYNDFDAAV----PFGGYKQSG 483
+ + +GL I ++ V K+ RL+ AG +IN + AV PFGG + SG
Sbjct: 455 IDTTTPYGLTGSIFAQDRVVVRKLTDRLRNAAGNFYIN--DKCTGAVVGEQPFGGARASG 512
Query: 484 YGREMG 489
+ G
Sbjct: 513 TNDKAG 518
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 154 bits (390), Expect = 2e-37
Identities = 118/420 (28%), Positives = 201/420 (47%), Gaps = 19/420 (4%)
Query: 87 WSTMDPKKRGSLLFKLADLIEAQKELIASIESA-DNGKTLALARGDVGL-VIDYIRSAAG 144
W K+R +L + ADL + + + + GK + A D +ID+ R A
Sbjct: 116 WERKPLKERAEILLRAADLAAGKYRMKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAV 175
Query: 145 YADKLGG-RTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKP 203
+A +L I+T ++ G I P+NF + + APAL+ GN + KP
Sbjct: 176 FAMELEHYEPISTKITKNTMQFRGMEGFVAAIAPFNFTAIGGNLPTAPALM-GNVSLWKP 234
Query: 204 ASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDV 263
++ L+ L +EAG+P G+++ +P G GD IT P + + FTGS + +
Sbjct: 235 SNTAVLSNYIIYELLEEAGMPPGILSFLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTI 294
Query: 264 AIKAAQS-----NLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRI 318
K A++ K+ E GGK+ H V A++ ++ +GQ CS+ SR+
Sbjct: 295 WRKVAENLDNYVTFPKLIGECGGKNFHFVHPSAHVDAVAAGTARSAWEYSGQKCSACSRM 354
Query: 319 YVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGK--KEGA 376
Y +I+ ++L + + EIK+G D S F +A+ + F + YID K +GA
Sbjct: 355 YAPKSIWPKILEKISA-IHKEIKLGDVRDGSVFLSAVIDDKAFARLKAYIDFAKTGADGA 413
Query: 377 SILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKF--STVDEAVALAND- 433
+++ GG+ GYFI+PT+ +++ EE+FGPVVT+ + S VDE +A D
Sbjct: 414 NVVLGGKCDDKTGYFIEPTLITVTDPKSKLLTEEMFGPVVTVLVYEDSKVDEVLATVKDA 473
Query: 434 SEFGLGAGIETENISVALKVAKRLK--AGTVWIN--TYNDFDAAVPFGGYKQSGYGREMG 489
+ +GL + +++ + L+ G +++N + PFGG + SG + G
Sbjct: 474 TPYGLTGAVFSQDKEFLYRARDVLRDAVGNMYLNDKSTGSIVGQQPFGGSRLSGTNDKAG 533
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 153 bits (386), Expect = 7e-37
Identities = 125/423 (29%), Positives = 203/423 (47%), Gaps = 22/423 (5%)
Query: 86 EWSTMDPKKRGSLLFKLADLIEA--QKELIASIESADNGKTLALARGDVGLVIDYIRSAA 143
+W + R + K ADL+ +++L A+ + + +ID+IR A
Sbjct: 124 KWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNA 183
Query: 144 GY---ADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVI 200
+ K + N + Y+ G + P+NF + + PAL+ GN V+
Sbjct: 184 YFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPALM-GNGVL 242
Query: 201 LKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIG 260
KP+ L+ + +EAG+P GVVN VP G GDTIT P + I FTGS
Sbjct: 243 WKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTF 302
Query: 261 RDVAIKAAQS-----NLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSG 315
+ + + N ++T E GGK+ H + A+++ + + + F+ GQ CS+
Sbjct: 303 NRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSAC 362
Query: 316 SRIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKE- 374
SR+YV ++++ Q + E ++K+G D S+F +A+ + F+ I YI+ KK
Sbjct: 363 SRMYVPESLWPQ-IKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSP 421
Query: 375 GASILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVD--EAVALAN 432
IL GG +KGYF+ PT+ + RI+ EEIFGPV++I + D E + L +
Sbjct: 422 NLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVH 481
Query: 433 DS-EFGL-GA--GIETENISVALKVAKRLKAGTVWIN--TYNDFDAAVPFGGYKQSGYGR 486
S +F L GA G + + + AL+ K + AG +IN + PFGG + SG
Sbjct: 482 TSTKFALTGAVFGQDEDFVKCALQEFK-MAAGNFYINDKSTGSVVGQQPFGGGRMSGTND 540
Query: 487 EMG 489
+ G
Sbjct: 541 KAG 543
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 147 bits (372), Expect = 3e-35
Identities = 116/421 (27%), Positives = 199/421 (46%), Gaps = 19/421 (4%)
Query: 86 EWSTMDPKKRGSLLFKLADLIEAQKEL-IASIESADNGKTLALARGDVGL-VIDYIRSAA 143
EW R + K AD++ + I + GKT+ A D +ID+ R A
Sbjct: 115 EWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNA 174
Query: 144 GYADKLGGRT-INTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILK 202
YA +L G+ I+ + Y+ G I P+NF + + APAL+ GN V+ K
Sbjct: 175 KYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWK 233
Query: 203 PASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRD 262
P+ L + + +EAG+P ++ VP G GDT+T+ + I FTGS +
Sbjct: 234 PSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKH 293
Query: 263 VAIKAAQS-----NLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSR 317
+ + AQ+ ++ E GGK+ H V A+++ + + F+ GQ CS+ SR
Sbjct: 294 LWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSR 353
Query: 318 IYVQDTIYDQLLSEFKTYLETEIKVGSPFDE-SNFQAAINNKAQFETILNYIDIGKKE-G 375
+YV +++ Q+ + IKVG P ++ F +A+ + F I +++ +
Sbjct: 354 LYVPHSLWPQIKGRLLEE-HSRIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPS 412
Query: 376 ASILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKF--STVDEAVALAND 433
+IL GG+ + GYF++P + + I+KEEIFGPV+++ + E + L +
Sbjct: 413 LTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDS 472
Query: 434 -SEFGLGAGIETENISVALKVAKRLK--AGTVWIN--TYNDFDAAVPFGGYKQSGYGREM 488
+ +GL + +++ V + K L+ AG +IN + PFGG + SG +
Sbjct: 473 TTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKP 532
Query: 489 G 489
G
Sbjct: 533 G 533
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 145 bits (366), Expect = 1e-34
Identities = 129/511 (25%), Positives = 232/511 (45%), Gaps = 35/511 (6%)
Query: 10 NLKIVEQDAVSITLPNGLTYQQPTGLFINNQFIKSQDGKTLKVE-NPST-EEIIVEVQSA 67
N+ + + D + +L + L IN + I + + L + NP+ ++++ V A
Sbjct: 38 NIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQA 97
Query: 68 TSQXXXXXXXXXXXXFNSEWSTMDPKKRGSLLFKLADLIEAQKEL-IASIESADNGKTLA 126
T + +W + R ++ K ADLI + + + GK +
Sbjct: 98 TEKDVMNAVKAAKDA-KKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVY 156
Query: 127 LARGD-VGLVIDYIRSAAGYADKL-GGRTINTGDGYANFTYKEPL-GVCGQIIPWNFPLM 183
A D + + D+ R YA L + + + DG N PL G + P+NF +
Sbjct: 157 QAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAI 216
Query: 184 MLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTIT 243
+ APAL+ GNTV+ KP+ L+ ++ +EAG+P GV+N +PG V D +
Sbjct: 217 AANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVL 275
Query: 244 NHPKIRKIAFTGSTDIGRDV-------AIKAAQSNLKKVTLELGGKSAHLVFEDANIKKT 296
+ FTGST++ + + ++ + ++ E GGK+ HLV ANI
Sbjct: 276 ADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHA 335
Query: 297 IPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKV-----GSPFDESN- 350
+ + + G F+ GQ CS+ SR+Y+ ++ ++ LS+ L+++ V SP N
Sbjct: 336 VLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNL 395
Query: 351 --FQAAINNKAQFETILNYIDIGKKE-GASILTGGERVGNKGYFIKPTVFYNVKEDMRIV 407
F + ++ F+ ++ I+ KK+ IL GG+ ++G+F+ PTV + D +
Sbjct: 396 RGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYM 455
Query: 408 KEEIFGPVVTISKFSTV---DEAVALANDSEFGLGAGIETENISVALKVAKRLK--AGTV 462
E FGP++T+ ++ + + N S++ L I ++ ++LK AG
Sbjct: 456 STEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNF 515
Query: 463 WINTYNDFDAAVP----FGGYKQSGYGREMG 489
+IN + AV FGG + SG + G
Sbjct: 516 YIN--DKCTGAVVSQQWFGGARMSGTDDKAG 544
>Hs20546780 [C] KOG2450 Aldehyde dehydrogenase
Length = 637
Score = 140 bits (353), Expect = 4e-33
Identities = 95/330 (28%), Positives = 167/330 (49%), Gaps = 13/330 (3%)
Query: 169 LGVCGQIIPWNFPLMMLSWKIAPALVAGNTVI--LKPASPTPLNALFFASLCKEAGIPAG 226
+GV G I+P F + + W+I PAL G TV+ + PASP PL A L E G G
Sbjct: 1 MGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPL---LLAQLAGELGPFPG 57
Query: 227 VVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHL 286
++N++ GP S+ + + P IRK+AF G+ + GR + ++ ++ L LG +S L
Sbjct: 58 ILNVLSGPA-SLVPILASQPGIRKVAFCGAPEEGRALR-RSLAGECAELGLALGTESLLL 115
Query: 287 VFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPF 346
+ + A++ + +V+ + + G G R+ +Q++++D+ + + + ++ G
Sbjct: 116 LTDTADVDSAVEGVVDAAWSDRGP---GGLRLLIQESVWDEAMRRLQERMG-RLRSGRGL 171
Query: 347 DESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKEDMRI 406
D + A A + + ++ + +GA + G+ V ++ F PT+ N+
Sbjct: 172 DGAVDMGA-RGAAACDLVQRFVREAQSQGAQVFQAGD-VPSERPFYPPTLVSNLPPASPC 229
Query: 407 VKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWINT 466
+ E+ PVV S F T EA+ +AN + G A + +E + AL++ L+ GTVWIN
Sbjct: 230 AQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWINA 289
Query: 467 YNDFDAAVPFGGYKQSGYGREMGEEAFESY 496
+ D +VP GG K+SG G + Y
Sbjct: 290 HGLRDPSVPTGGCKESGCSWHGGPDGLYEY 319
Score = 72.8 bits (177), Expect = 1e-12
Identities = 71/269 (26%), Positives = 112/269 (41%), Gaps = 13/269 (4%)
Query: 18 AVSITLPNGLTY----QQPTGLFINNQFIKSQDGKTLKVENPSTEEIIVEVQSATSQXXX 73
AV TLP G P GLF+ +F ++ ++ + S+ + V ++
Sbjct: 344 AVPSTLPAGPEIGPSPAPPYGLFVGGRF-QAPGARSSRPIRDSSGNLHGYVAEGGAKDIR 402
Query: 74 XXXXXXXXXFNSEWSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVG 133
F W+ P R +LL+ LA +E +K +AS G L A +V
Sbjct: 403 GAVEAAHQAFPG-WAGQSPGARAALLWALAAALERRKSTLAS-RLERQGAELKAAEAEVE 460
Query: 134 LVIDYIRSAAGYADKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPAL 193
L +R+ G G +EPLGV + P +PL+ +APAL
Sbjct: 461 LSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPAL 520
Query: 194 VAGNTVILKPASPTPLNALFFASLCKEAG--IPAGVVNIVPGPGRSVGDTITNHPKIRKI 251
GNTV++ P++ PL AL +C++ PAG+ N+V G + + H ++ +
Sbjct: 521 AYGNTVVMVPSAACPLLAL---EVCQDMATVFPAGLANVVTGDRDHLTRCLALHQDVQAM 577
Query: 252 AFTGSTDIGRDVAIKAAQSNLKKVTLELG 280
+ GS G A+ NLK V G
Sbjct: 578 WYFGSAQ-GSQFVEWASAGNLKPVWASRG 605
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 135 bits (339), Expect = 2e-31
Identities = 102/340 (30%), Positives = 174/340 (51%), Gaps = 22/340 (6%)
Query: 175 IIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPAGVVNIVPGP 234
I P+NFPL++ +A AL AGNT++LKP+ TP A+ +L AG P G++ +V G
Sbjct: 135 IAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQG- 193
Query: 235 GRSVGDT--ITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHLV---FE 289
++ +T + + K I +TGS +G VA KAA+S L LELGGKS + F+
Sbjct: 194 --AIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKS-LTPCVLELGGKSPTFITENFK 250
Query: 290 DANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPFDE- 348
+NIK + + G F N+GQIC S + V +IY +++ E ++ L + FDE
Sbjct: 251 ASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLN---EFYPSFDEQ 307
Query: 349 SNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG---YFIKPTVFYNVKEDMR 405
++F I+ A + + + I G+ I+ + + + PT+ YN+ D
Sbjct: 308 TDFTRMIHEPAYKKAVAS---INSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDP 364
Query: 406 IVKEEIFGPVVTISKFSTVDEAV-ALANDSEFGLGAGIETENISVALKVAKRLKAG--TV 462
++K+E F PV+ I ++ +DE + + + + L I +++ + ++ RL++G V
Sbjct: 365 LMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVV 424
Query: 463 WINTYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+ PFGG SGYG G F +++ + +
Sbjct: 425 GDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTI 464
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 134 bits (338), Expect = 2e-31
Identities = 105/339 (30%), Positives = 167/339 (48%), Gaps = 13/339 (3%)
Query: 166 KEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPA 225
K+P GV I PWN+P+ M+ + PA+ AGNTV++KP+ + A F L + +
Sbjct: 101 KDPKGVVLIISPWNYPVSMILLPMVPAIAAGNTVVIKPSELSENVAATFEKLIPKY-FES 159
Query: 226 GVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAH 285
V +V G D + + I +TG + + + + AA +L VTLELGGK
Sbjct: 160 KYVTVVNGGIPETTDLLKE--RFDHILYTGCPPVAK-IIMTAAAKHLTPVTLELGGKCPV 216
Query: 286 LVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSP 345
+V +DA+I + + G + N GQ C + I V T+ +L++ + Y+ G
Sbjct: 217 VVEDDADIDISAKRIAWGKWLNCGQTCLAPDYILVNSTVKPKLVAAIRKYVNE--FYGED 274
Query: 346 FDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKEDMR 405
S A + N+ F+ I +D K +GA +L GGER +I PTV +V++
Sbjct: 275 VKASKDYARMINQRHFDRISGLLD--KTQGA-VLIGGER-DRADLYIPPTVL-DVEKSDP 329
Query: 406 IVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWIN 465
+ +EIFGPV+ I + E++ D E L A I T N + ++ +G V +N
Sbjct: 330 FMHDEIFGPVLPIITVQSFSESLEYIADGEKPLAAYIFTRNEAKVKRLLNETSSGGVTVN 389
Query: 466 --TYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+ +PFGG SG GR G+ F+++T K+V
Sbjct: 390 DVLMHITVDTLPFGGVGVSGMGRYRGKYGFDTFTHEKSV 428
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 134 bits (337), Expect = 3e-31
Identities = 115/402 (28%), Positives = 191/402 (46%), Gaps = 14/402 (3%)
Query: 104 DLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYADKLGGRTINTGDGYANF 163
+++ A ++ + E + ++L R + L + +++ A + ++ T A
Sbjct: 51 EIVAALRDDLGKPELESSVYEVSLLRNSIKLALKQLKN--WMAPEKAKTSLTTFPASAEI 108
Query: 164 TYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGI 223
EPLGV I WN+P ++ + A+ AGN V+LKP+ P ++ L ++
Sbjct: 109 V-SEPLGVVLVISAWNYPFLLSIDPVIGAISAGNAVVLKPSELAPASSALLTKLLEQYLD 167
Query: 224 PAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKS 283
P+ V +V G + K KI +TGS+ IGR V + AA +L V LELGGKS
Sbjct: 168 PS-AVRVVEGAVTETSALL--EQKWDKIFYTGSSKIGR-VIMAAAAKHLTPVVLELGGKS 223
Query: 284 AHLVFEDANIKKTIPNLVNGIFK-NAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKV 342
+V D ++K T+ ++ G + N GQ C S I +L+ K LE E
Sbjct: 224 PVVVDSDTDLKVTVRRIIVGKWGCNNGQACVSPDYILTTKEYAPKLIDAMK--LELEKFY 281
Query: 343 GSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKE 402
G ES + I N F+ + +D K+ I+ GGE+ + I PT+ +V
Sbjct: 282 GKNPIESKDMSRIVNSNHFDRLSKLLD-EKEVSDKIVYGGEK-DRENLKIAPTILLDVPL 339
Query: 403 DMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTV 462
D I+ EEIFGP++ I + ++E+ + L A + T N + + A + AG +
Sbjct: 340 DSLIMSEEIFGPLLPILTLNNLEESFDVIRSRPKPLAAYLFTHNKKLKERFAATVSAGGI 399
Query: 463 WINTYNDFDA--AVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+N A +PFGG +SG G G+ +F++++ KAV
Sbjct: 400 VVNDIAVHLALHTLPFGGVGESGMGAYHGKFSFDAFSHKKAV 441
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 126 bits (317), Expect = 7e-29
Identities = 99/343 (28%), Positives = 167/343 (47%), Gaps = 13/343 (3%)
Query: 163 FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAG 222
+ K+P GV I PWN+P+ M+ + P++ AGNT+++KP+ + A+ F L +
Sbjct: 99 YIVKDPKGVVLVISPWNYPVSMVLLPMIPSIAAGNTIVIKPSELSENTAILFEKLIPKYF 158
Query: 223 IPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGK 282
P V IV G + + + I +TG + + + + AA +L VTLELGGK
Sbjct: 159 DPK-YVTIVNGGIPETTELLKE--RFDHIIYTGCPPVAK-IIMAAAAKHLTPVTLELGGK 214
Query: 283 SAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKV 342
+V +DA+I+ + + G + N GQ C + I V + ++ + L+ E
Sbjct: 215 CPVVVEDDADIEISAQRIARGKWLNCGQTCLAPDYILVSSATKPKFVAAIQKCLK-EFYG 273
Query: 343 GSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKG-YFIKPTVFYNVK 401
G+ + ++ IN + F+ I +D K +L G E ++ FI PTV +V+
Sbjct: 274 GNAKESKDYSRVINQR-HFDRISALLDESK---GVVLAGNEESRDRSDRFIPPTVL-DVE 328
Query: 402 EDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGT 461
+ + +EIFGPV+ I + E++ N E L A I T++ + + +G
Sbjct: 329 KTDPFMHDEIFGPVLPIITVKNLCESIDFINKGEKPLAAYIFTKDEAKVQRFLNETTSGG 388
Query: 462 VWINTYNDFDAAV--PFGGYKQSGYGREMGEEAFESYTQIKAV 502
V +N A + PFGG SG GR G+ F+++T K+V
Sbjct: 389 VTVNDVIMHVAVITLPFGGVGVSGMGRYRGKFGFDTFTHEKSV 431
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 124 bits (312), Expect = 3e-28
Identities = 96/345 (27%), Positives = 164/345 (46%), Gaps = 22/345 (6%)
Query: 167 EPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPAG 226
+PLGV I WN+P ++ + A+ AGN VI+KP+ + A A L + +
Sbjct: 100 QPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQD 158
Query: 227 VVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHL 286
+ ++ G + + + I +TG+T +G+ + ++AA +L VTLELGGKS
Sbjct: 159 LYIVINGGVEETTELLKQ--RFDHIFYTGNTAVGK-IVMEAAAKHLTPVTLELGGKSPCY 215
Query: 287 VFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPF 346
+ +D ++ + G + N GQ C + I + ++ +Q++ + K ++ G
Sbjct: 216 IDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFY--GENI 273
Query: 347 DESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKEDMRI 406
ES I N F+ IL+ + EG I GGE +I PTV +V ++
Sbjct: 274 KESPDYERIINLRHFKRILSLL-----EGQKIAFGGE-TDEATRYIAPTVLTDVDPKTKV 327
Query: 407 VKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWIN- 465
++EEIFGP++ I VDEA+ N+ E L + + N + ++ +G V N
Sbjct: 328 MQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGND 387
Query: 466 -----TYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIK 505
T N F PFGG SG G G+ +F++++ + +K
Sbjct: 388 VIMHFTLNSF----PFGGVGSSGMGAYHGKHSFDTFSHQRPCLLK 428
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 124 bits (312), Expect = 3e-28
Identities = 96/345 (27%), Positives = 164/345 (46%), Gaps = 22/345 (6%)
Query: 167 EPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPAG 226
+PLGV I WN+P ++ + A+ AGN VI+KP+ + A A L + +
Sbjct: 100 QPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQD 158
Query: 227 VVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHL 286
+ ++ G + + + I +TG+T +G+ + ++AA +L VTLELGGKS
Sbjct: 159 LYIVINGGVEETTELLKQ--RFDHIFYTGNTAVGK-IVMEAAAKHLTPVTLELGGKSPCY 215
Query: 287 VFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPF 346
+ +D ++ + G + N GQ C + I + ++ +Q++ + K ++ G
Sbjct: 216 IDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFY--GENI 273
Query: 347 DESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKEDMRI 406
ES I N F+ IL+ + EG I GGE +I PTV +V ++
Sbjct: 274 KESPDYERIINLRHFKRILSLL-----EGQKIAFGGE-TDEATRYIAPTVLTDVDPKTKV 327
Query: 407 VKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWIN- 465
++EEIFGP++ I VDEA+ N+ E L + + N + ++ +G V N
Sbjct: 328 MQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGND 387
Query: 466 -----TYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIK 505
T N F PFGG SG G G+ +F++++ + +K
Sbjct: 388 VIMHFTLNSF----PFGGVGSSGMGAYHGKHSFDTFSHQRPCLLK 428
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 124 bits (310), Expect = 4e-28
Identities = 98/338 (28%), Positives = 163/338 (47%), Gaps = 16/338 (4%)
Query: 163 FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAG 222
F +KEP G+ I PWN+PL + + L AGN V+LKP+ + A + +
Sbjct: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQY- 76
Query: 223 IPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGK 282
+ +V G + G + + K+ I FTGS +G+ + + AA +L VTLELGGK
Sbjct: 77 LDQSCFAVVLGGPQETGQLLEH--KLDYIFFTGSPRVGK-IVMTAATKHLTPVTLELGGK 133
Query: 283 SAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKV 342
+ V ++ + + + + NAGQ C + + + ++LL ++ + T
Sbjct: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTI-TRFYG 192
Query: 343 GSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKE 402
P N IN K QF+ + + G+ + GG+ + Y I PTV +V+E
Sbjct: 193 DDPQSSPNLGRIINQK-QFQRLRALLGCGR-----VAIGGQSNESDRY-IAPTVLVDVQE 245
Query: 403 DMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTV 462
+++EEIFGP++ I +VDEA+ N E L + + V ++ +R +G+
Sbjct: 246 TEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLERTSSGSF 305
Query: 463 WIN---TYNDFDAAVPFGGYKQSGYGREMGEEAFESYT 497
N TY +VPFGG SG GR G+ F++++
Sbjct: 306 GGNEGFTYISL-LSVPFGGVGHSGMGRYHGKFTFDTFS 342
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 122 bits (307), Expect = 1e-27
Identities = 115/422 (27%), Positives = 201/422 (47%), Gaps = 27/422 (6%)
Query: 95 RGSLLFKLADLIEAQKELIASIESADNGKT--------LALARGDVGLVIDYIRSAAGYA 146
R + L L ++ K+L+ + D K+ +A+++G+V L + +R A
Sbjct: 26 RAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLR--AWMK 83
Query: 147 DKLGGRTINTGDGYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASP 206
D+ + + T A F KEP G+ I PWN+PL + + AL AGN V+LKP+
Sbjct: 84 DERVPKNLATQLDSA-FIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEI 142
Query: 207 TPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIK 266
+ A + + + +V G + G + + + I FTGS +G+ + +
Sbjct: 143 SKNVEKILAEVLPQY-VDQSCFAVVLGGPQETGQLLEH--RFDYIFFTGSPRVGK-IVMT 198
Query: 267 AAQSNLKKVTLELGGKSAHLVFEDANIKKTIPNLVNGI-FKNAGQICSSGSRIYVQDTIY 325
AA +L VTLELGGK+ V ++ + +T+ N V + NAGQ C + + +
Sbjct: 199 AAAKHLTPVTLELGGKNPCYVDDNCD-PQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQ 257
Query: 326 DQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERV 385
++LL ++ + T P N IN K QF+ + + G+ + GG+
Sbjct: 258 ERLLPALQSTI-TRFYGDDPQSSPNLGRIINQK-QFQRLRALLGCGR-----VAIGGQSD 310
Query: 386 GNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETE 445
+ Y I PTV +V+E +++EEIFGP++ I ++DEA+ N E L +
Sbjct: 311 ESDRY-IAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSN 369
Query: 446 NISVALKVAKRLKAGTVWINT--YNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVR 503
+ V +V + +G N + A++PFGG SG GR G+ +F++++ +A
Sbjct: 370 SSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACL 429
Query: 504 IK 505
++
Sbjct: 430 LR 431
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 120 bits (300), Expect = 6e-27
Identities = 93/345 (26%), Positives = 164/345 (46%), Gaps = 14/345 (4%)
Query: 163 FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAG 222
+ + EPLGV I WN+P + + A+ AGN V+LKP+ + A A++ +
Sbjct: 99 YIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY- 157
Query: 223 IPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGK 282
+ + ++ G + + + I +TGST +G+ + + AA +L VTLELGGK
Sbjct: 158 LDKDLYPVINGGVPETTELLKE--RFDHILYTGSTGVGK-IIMTAAAKHLTPVTLELGGK 214
Query: 283 SAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKV 342
S V ++ ++ + G F N+GQ C + I +I +Q++ + K L+
Sbjct: 215 SPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKE--FY 272
Query: 343 GSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKE 402
G +S I + F+ ++ I EG + GG Y I PT+ +V
Sbjct: 273 GEDAKKSRDYGRIISARHFQRVMGLI-----EGQKVAYGGTGDAATRY-IAPTILTDVDP 326
Query: 403 DMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTV 462
+++EEIFGPV+ I +++EA+ N E L + + N V K+ +G V
Sbjct: 327 QSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGV 386
Query: 463 WIN--TYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIK 505
N + ++PFGG SG G G+++FE+++ ++ ++
Sbjct: 387 AANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVR 431
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 120 bits (300), Expect = 6e-27
Identities = 93/345 (26%), Positives = 164/345 (46%), Gaps = 14/345 (4%)
Query: 163 FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAG 222
+ + EPLGV I WN+P + + A+ AGN V+LKP+ + A A++ +
Sbjct: 99 YIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY- 157
Query: 223 IPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGK 282
+ + ++ G + + + I +TGST +G+ + + AA +L VTLELGGK
Sbjct: 158 LDKDLYPVINGGVPETTELLKE--RFDHILYTGSTGVGK-IIMTAAAKHLTPVTLELGGK 214
Query: 283 SAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKV 342
S V ++ ++ + G F N+GQ C + I +I +Q++ + K L+
Sbjct: 215 SPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKE--FY 272
Query: 343 GSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKE 402
G +S I + F+ ++ I EG + GG Y I PT+ +V
Sbjct: 273 GEDAKKSRDYGRIISARHFQRVMGLI-----EGQKVAYGGTGDAATRY-IAPTILTDVDP 326
Query: 403 DMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTV 462
+++EEIFGPV+ I +++EA+ N E L + + N V K+ +G V
Sbjct: 327 QSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGV 386
Query: 463 WIN--TYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAVRIK 505
N + ++PFGG SG G G+++FE+++ ++ ++
Sbjct: 387 AANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVR 431
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 118 bits (296), Expect = 2e-26
Identities = 108/406 (26%), Positives = 175/406 (42%), Gaps = 42/406 (10%)
Query: 122 GKTLALARGDVGLVIDYIRSAAGYADKLGG-----------------RTINTGD-----G 159
GKTL A DV ++D++R + +L R ++ G G
Sbjct: 165 GKTLRQAEMDVAELVDFMRINPVFLRELANYEPIRDIQNNCRNSMRLRGLSGGSPYNLYG 224
Query: 160 YANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCK 219
+ +F G I P+NF + + PAL+ GN+VI KP+ L+ F +
Sbjct: 225 FLSFYNFLFAGFVAAISPFNFTGIAANLAYTPALM-GNSVIWKPSDSAILSNYFVFKALR 283
Query: 220 EAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQS-----NLKK 274
EAG+P GVVN VP + +T HPK+ I FTG++ + + + AQ+ N +
Sbjct: 284 EAGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPR 343
Query: 275 VTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSE--F 332
+ E GGK+ H V A + + + F+ AGQ CSS S +YV ++++ + E
Sbjct: 344 LVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLL 403
Query: 333 KTYLETEIKVGSPFDESNFQAAINNKA--QFETILNYIDIGKKEGASILTGGERVGNKGY 390
+ ++ + + +S A IN +A + L YID + IL GG +GY
Sbjct: 404 EITASLVVRQDATYCDSFCSAVINRRAYDRIYMWLRYID--QSPSCQILVGGSCDKRRGY 461
Query: 391 FIKPTVFYNVKEDMRIVKEEIFGPVVTI-----SKFSTVDEAVALANDSEFGLGAGIETE 445
++ PTV D I +EE+ P++ + K E VA N G + +
Sbjct: 462 YVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTG-SVFAQDQ 520
Query: 446 NISVALKVAKRLKAGTVWINTYND--FDAAVPFGGYKQSGYGREMG 489
N A R+ G + +N + PFG +G ++G
Sbjct: 521 NFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLG 566
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 103 bits (257), Expect = 6e-22
Identities = 84/305 (27%), Positives = 137/305 (44%), Gaps = 20/305 (6%)
Query: 165 YKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIP 224
Y +P GV I WN+PL +L +A A+ AGN V++KP+ A F A + IP
Sbjct: 101 YNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADV-----IP 155
Query: 225 AGVVN----IVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELG 280
+ N +V G + + + + I +TGST +G+ + AA L TLELG
Sbjct: 156 KYLDNDCYPVVCGGPSETAELL--NQRFDYIFYTGSTRVGK-IIHAAANKYLTPTTLELG 212
Query: 281 GKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEI 340
GKS + + +++ + ++ G N GQ C + I + ++ + E K L+
Sbjct: 213 GKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKE-- 270
Query: 341 KVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNV 400
G S + + N F+ +L + G+ ER FI+PT+ +V
Sbjct: 271 WYGENIQSSPDLSRVINANNFQRLLGLMKSGRVAVGGNYDASER------FIEPTILVDV 324
Query: 401 KEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAG 460
KE I++EEIFGP++ I + +A+ N E L I T V ++G
Sbjct: 325 KETDPIMEEEIFGPILPIFNVESAYDAIKFINARESPLVLYIFTPTAEVQNLFINGTQSG 384
Query: 461 TVWIN 465
+ +N
Sbjct: 385 GLCVN 389
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 96.3 bits (238), Expect = 1e-19
Identities = 89/341 (26%), Positives = 144/341 (42%), Gaps = 63/341 (18%)
Query: 167 EPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAGIPAG 226
EP G + WNFP+ + + A+ AGNTV+LK + +P NA F + A +
Sbjct: 107 EPYGTVLVLSSWNFPISLSLDPLIGAIAAGNTVLLKSSELSP-NASAFLAKTIPAYLDTK 165
Query: 227 VVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGKSAHL 286
+ ++ G G V + H + KI FTGS IGR + AAQ +L VTLELGGKS
Sbjct: 166 AIKVIEG-GPDVATILLQH-QWDKIFFTGSPKIGRIIMAAAAQ-HLTPVTLELGGKS--- 219
Query: 287 VFEDANIKKTIPNLVNGIFKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIKVGSPF 346
C S + ++ + L+ K +++ G
Sbjct: 220 -------------------------CISVDYVLIEKSFAPTLIDMLKPTIKSFF--GENP 252
Query: 347 DESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKEDMRI 406
ES + I NK + + + +PT+ + D I
Sbjct: 253 KESGCLSRIANKHHVQRLSRLLSDP---------------------RPTILLDPPLDSEI 291
Query: 407 VKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWINT 466
+ EEIFGP++ I + E++ + N L T + ++ ++ +G+V T
Sbjct: 292 MNEEIFGPILPIITVRDIQESIGIINTKPKPLAIYAFTNDENLKTRILSETSSGSV---T 348
Query: 467 YND-----FDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+ND A+PFGG +SG GR G+ +F+ ++ KA+
Sbjct: 349 FNDVMIQYMCDALPFGGVGESGIGRYHGKYSFDCFSHEKAI 389
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 94.7 bits (234), Expect = 3e-19
Identities = 105/428 (24%), Positives = 180/428 (41%), Gaps = 31/428 (7%)
Query: 87 WSTMDPKKRGSLLFKLADLIEAQKELIASIESADNGKTLALARGDVGLVIDYIRSAAGYA 146
WS + +R ++ + A +IE + + KT A D+ ++ +R+ A Y
Sbjct: 116 WSLVPIAQRLAIWRRAATIIEEDELRLRVFLMMTLSKTADDATRDIRRLLTSLRANADYL 175
Query: 147 DKLGGRTINT-GDG--YANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKP 203
+ L GD + +F + G + P+ + S + PAL+ GNTV+ P
Sbjct: 176 EHLSELRFEIQGDMNVFPSFHLRPMDGFVAALAPFESVALSSSLALCPALM-GNTVLWNP 234
Query: 204 A-SPTPLNALFFASLCKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRD 262
+ P++ L F + +EAG+P+GV+N VP R DTIT+ + S R
Sbjct: 235 SLEVAPVSYLIFRAF-QEAGLPSGVINFVPANERLFLDTITDAVHFAGLNTQASAAFYRH 293
Query: 263 VAIKAAQSNLKK------VTLELGGKSAHLVFEDANIKKTIPNLVNGIFKNAGQICSSGS 316
V K +++ + E G++ H V A ++ + V F AGQ +S S
Sbjct: 294 VH-KLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFGFAGQYANSLS 352
Query: 317 RIYVQDTIYDQLLSEFKTYLETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGA 376
R+YV +++ +L E E ++ +G P + A+ + F + + + +
Sbjct: 353 RMYVPSSMWPRLREELVEATE-QLTIGDPIESETDIGAMVHINDFRRMQKLLQ--RTKNM 409
Query: 377 SILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTISKFS--TVDEAVAL-AND 433
L GG + G F+ PT+ ++ E GP + + +S + EA+ L AN
Sbjct: 410 EQLCGGSCDDSTGRFVDPTIVRVSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQ 469
Query: 434 SEFGLGAGIETENISVALKVAK--RLKAGTVWIN------TYNDFDAAVPFGGYKQSGYG 485
S + L I V L R+ A +++N TY PFGG + SG
Sbjct: 470 SRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTY----GLTPFGGNRLSGTN 525
Query: 486 REMGEEAF 493
+ G F
Sbjct: 526 DKSGSAYF 533
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 73.2 bits (178), Expect = 9e-13
Identities = 61/210 (29%), Positives = 99/210 (47%), Gaps = 8/210 (3%)
Query: 163 FTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLCKEAG 222
F KEP G+ I PWN+PL + + AL AGN V+LKP+ + A + +
Sbjct: 62 FIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY- 120
Query: 223 IPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTLELGGK 282
+ +V G + G + + + I FTGS +G+ + + AA +L VTLELGGK
Sbjct: 121 VDQSCFAVVLGGPQETGQLLEH--RFDYIFFTGSPRVGK-IVMTAAAKHLTPVTLELGGK 177
Query: 283 SAHLVFEDANIKKTIPNLVNGI-FKNAGQICSSGSRIYVQDTIYDQLLSEFKTYLETEIK 341
+ V ++ + +T+ N V + NAGQ C + + + ++LL ++ + T
Sbjct: 178 NPCYVDDNCD-PQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTI-TRFY 235
Query: 342 VGSPFDESNFQAAINNKAQFETILNYIDIG 371
P N IN K QF+ + + G
Sbjct: 236 GDDPQSSPNLGRIINQK-QFQRLRALLGCG 264
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 71.2 bits (173), Expect = 3e-12
Identities = 86/353 (24%), Positives = 147/353 (41%), Gaps = 37/353 (10%)
Query: 160 YANFTYKEPLGVCGQIIP-WNFPLMMLSWK-IAPALVAGNTVILKPASPTPLNALFFASL 217
+ +F YK L C Q + + +LS + + A+ AGN V+LKP+ P + A L
Sbjct: 162 FLDFEYKIILYACNQRVKELDGSRNVLSVEPVIGAIAAGNAVVLKPSEIAPAASSLLAKL 221
Query: 218 CKEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLKKVTL 277
E + + ++ G T K KI FT + + + +K L V
Sbjct: 222 FSEY-LDNTTIRVIEGGVPET--TALLDQKWDKIFFTDLSLLLKHKIVKFRSHTLIVVLW 278
Query: 278 ELGGKSAHLVFEDANIKKTIPNLVNGIFK-NAGQICSSGSRIYVQDTIYDQLLSEFKTYL 336
+K ++ G + N+GQ C + +L+ KT L
Sbjct: 279 ---------------LKVAARRIIAGKWACNSGQACIGVDYVITTKDFASKLIDALKTEL 323
Query: 337 ETEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEG-ASILTGGERVGNKGYFIKPT 395
ET G ES + I N F+ + + + K+ G A+ + G R+ I PT
Sbjct: 324 ETFF--GQNALESKDLSRIVNSFHFKRLESML---KENGVANKIVHGGRITEDKLKISPT 378
Query: 396 VFYNVKEDMRIVKEEIFGPVVTISKFSTVDEAVALANDSEFGLGAGIETENISVALKVAK 455
+ +V E +++EEIFGP++ I +++ + L A + T N + + +
Sbjct: 379 ILLDVPEASSMMQEEIFGPLLPIITVQKIEDGFQVIRSKPKPLAAYLFTNNKELEKQFVQ 438
Query: 456 RLKAGTVWIN------TYNDFDAAVPFGGYKQSGYGREMGEEAFESYTQIKAV 502
+ AG + IN T D +PFGG +SG G G+ ++E+++ K V
Sbjct: 439 DVSAGGITINDTVLHVTVKD----LPFGGVGESGIGAYHGKFSYETFSHKKGV 487
>Hs20479244 [C] KOG2450 Aldehyde dehydrogenase
Length = 292
Score = 70.1 bits (170), Expect = 7e-12
Identities = 42/138 (30%), Positives = 69/138 (49%), Gaps = 1/138 (0%)
Query: 359 AQFETILNYIDIGKKEGASILTGGERVGNKGYFIKPTVFYNVKEDMRIVKEEIFGPVVTI 418
A + + ++ + +GA + G+ V ++ F PT+ N+ + E+ PVV
Sbjct: 29 AACDLVQRFVREAQSQGAQVFQAGD-VPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVA 87
Query: 419 SKFSTVDEAVALANDSEFGLGAGIETENISVALKVAKRLKAGTVWINTYNDFDAAVPFGG 478
S F T EA+ +AN + G A + +E + AL++ L+ GTVWIN + D +VP GG
Sbjct: 88 SPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLRDPSVPTGG 147
Query: 479 YKQSGYGREMGEEAFESY 496
K+SG G + Y
Sbjct: 148 CKESGCSWHGGPDGLYEY 165
>At5g62530 [C] KOG2451 Aldehyde dehydrogenase
Length = 563
Score = 53.1 bits (126), Expect = 9e-07
Identities = 65/282 (23%), Positives = 119/282 (42%), Gaps = 35/282 (12%)
Query: 159 GYANFTYKEPLGVCGQIIPWNFPLMMLSWKIAPALVAGNTVILKPASPTPLNALFFASLC 218
G + Y+ P G + P+NFPL + ++ AL GN +LK S + L
Sbjct: 194 GQQSHGYRWPYGPVTIVTPFNFPLEIPLLQLMGALYMGNKPLLKVDSKVSIVMEQMMRLL 253
Query: 219 KEAGIPAGVVNIVPGPGRSVGDTITNHPKIRKIAFTGSTDIGRDVAIKAAQSNLK-KVTL 277
G+PA V+ + G+++ + I R FTGS+ + +A+ +LK ++ L
Sbjct: 254 HYCGLPAEDVDFINSDGKTM-NKILLEANPRMTLFTGSSRVAEKLAL-----DLKGRIRL 307
Query: 278 ELGGKSAHLVFEDA-NIKKTIPNLVNGIFKNAGQICSSGSRIYVQDT-IYDQLLSEFKTY 335
E G ++ D + + +GQ CS+ S ++V + L+S+ K
Sbjct: 308 EDAGFDWKVLGPDVQEVDYVAWQCDQDAYACSGQKCSAQSMLFVHENWSKTPLVSKLKEL 367
Query: 336 LE----TEIKVGSPFDESNFQAAINNKAQFETILNYIDIGKKEGASILTGGERVGNKGY- 390
E ++ +G +A E + N + I G+ +L GG+ + N
Sbjct: 368 AERRKLEDLTIGPVL-------TFTTEAMLEHMENLLQI---PGSKLLFGGKELKNHSIP 417
Query: 391 ----FIKPTVFYNVKEDM-------RIVKEEIFGPVVTISKF 421
++PT Y E++ +V +EIFGP ++++
Sbjct: 418 SIYGALEPTAVYVPIEEILKDNKTYELVTKEIFGPFQIVTEY 459
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.135 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,223,797
Number of Sequences: 60738
Number of extensions: 1278820
Number of successful extensions: 2336
Number of sequences better than 1.0e-05: 76
Number of HSP's better than 0.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2002
Number of HSP's gapped (non-prelim): 81
length of query: 507
length of database: 30,389,216
effective HSP length: 111
effective length of query: 396
effective length of database: 23,647,298
effective search space: 9364330008
effective search space used: 9364330008
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)