ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV6218 good R KOG0725 General function prediction only Reductases with broad range of substrate specificities
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV6218 2137425 2136586 -280
(280 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC8E11.10 [R] KOG0725 Reductases with broad range of substrate... 252 5e-67
SPCC1739.08c [R] KOG0725 Reductases with broad range of substrat... 197 1e-50
SPAC22A12.17c [R] KOG0725 Reductases with broad range of substra... 188 6e-48
At2g29170 [R] KOG0725 Reductases with broad range of substrate s... 117 1e-26
At1g24360 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP... 117 2e-26
7295487 [R] KOG0725 Reductases with broad range of substrate spe... 115 7e-26
At2g29350 [R] KOG0725 Reductases with broad range of substrate s... 115 9e-26
At2g29300 [R] KOG0725 Reductases with broad range of substrate s... 114 2e-25
At2g29150 [R] KOG0725 Reductases with broad range of substrate s... 114 2e-25
At2g29370 [R] KOG0725 Reductases with broad range of substrate s... 113 3e-25
At2g29340 [R] KOG0725 Reductases with broad range of substrate s... 112 4e-25
CE19894 [R] KOG0725 Reductases with broad range of substrate spe... 111 1e-24
Hs19923817 [R] KOG0725 Reductases with broad range of substrate ... 110 2e-24
At2g29320 [R] KOG0725 Reductases with broad range of substrate s... 108 1e-23
At2g29310 [R] KOG0725 Reductases with broad range of substrate s... 106 3e-23
At2g29360 [R] KOG0725 Reductases with broad range of substrate s... 106 4e-23
At1g63380 [R] KOG0725 Reductases with broad range of substrate s... 105 9e-23
At1g07440 [R] KOG0725 Reductases with broad range of substrate s... 104 2e-22
CE09969 [R] KOG0725 Reductases with broad range of substrate spe... 102 6e-22
CE04339 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP r... 100 2e-21
At2g30670 [R] KOG0725 Reductases with broad range of substrate s... 100 2e-21
CE19130 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP r... 100 3e-21
At2g29260 [R] KOG0725 Reductases with broad range of substrate s... 100 3e-21
At2g29290 [R] KOG0725 Reductases with broad range of substrate s... 100 4e-21
At4g05530 [R] KOG0725 Reductases with broad range of substrate s... 99 7e-21
7296705 [R] KOG0725 Reductases with broad range of substrate spe... 98 1e-20
SPAC922.06 [R] KOG0725 Reductases with broad range of substrate ... 97 3e-20
Hs15277342 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-AC... 97 3e-20
At5g06060 [R] KOG0725 Reductases with broad range of substrate s... 97 3e-20
At3g55310 [R] KOG0725 Reductases with broad range of substrate s... 97 3e-20
At1g62610 [R] KOG0725 Reductases with broad range of substrate s... 97 3e-20
Hs10337605 [R] KOG0725 Reductases with broad range of substrate ... 96 4e-20
At2g29330 [R] KOG0725 Reductases with broad range of substrate s... 96 6e-20
At3g26760 [R] KOG0725 Reductases with broad range of substrate s... 95 1e-19
At1g07450 [R] KOG0725 Reductases with broad range of substrate s... 95 1e-19
At3g26770 [R] KOG0725 Reductases with broad range of substrate s... 94 2e-19
At5g18210 [R] KOG0725 Reductases with broad range of substrate s... 94 2e-19
At3g05260 [R] KOG0725 Reductases with broad range of substrate s... 94 3e-19
At3g51680 [R] KOG0725 Reductases with broad range of substrate s... 93 5e-19
At1g54870 [R] KOG0725 Reductases with broad range of substrate s... 93 5e-19
At4g03140 [R] KOG0725 Reductases with broad range of substrate s... 92 1e-18
At3g03980 [R] KOG0725 Reductases with broad range of substrate s... 91 1e-18
CE10908 [R] KOG0725 Reductases with broad range of substrate spe... 89 9e-18
Hs7705907 [R] KOG0725 Reductases with broad range of substrate s... 88 1e-17
At3g46170 [R] KOG0725 Reductases with broad range of substrate s... 88 2e-17
At3g42960 [R] KOG0725 Reductases with broad range of substrate s... 88 2e-17
At2g47120 [R] KOG0725 Reductases with broad range of substrate s... 88 2e-17
At2g47140 [R] KOG0725 Reductases with broad range of substrate s... 87 3e-17
Hs4503301 [R] KOG0725 Reductases with broad range of substrate s... 86 5e-17
CE21092 [R] KOG0725 Reductases with broad range of substrate spe... 86 5e-17
At2g47130 [R] KOG0725 Reductases with broad range of substrate s... 86 5e-17
At3g04000 [R] KOG0725 Reductases with broad range of substrate s... 86 6e-17
At3g29260 [R] KOG0725 Reductases with broad range of substrate s... 86 8e-17
CE02315 [R] KOG0725 Reductases with broad range of substrate spe... 85 1e-16
Hs4504479 [IR] KOG4169 15-hydroxyprostaglandin dehydrogenase and... 84 2e-16
At5g50700 [Q] KOG1205 Predicted dehydrogenase 84 2e-16
At5g50600 [Q] KOG1205 Predicted dehydrogenase 84 2e-16
CE21095 [R] KOG0725 Reductases with broad range of substrate spe... 83 4e-16
7296704 [R] KOG0725 Reductases with broad range of substrate spe... 83 5e-16
7290108 [R] KOG0725 Reductases with broad range of substrate spe... 82 1e-15
At5g50770 [Q] KOG1205 Predicted dehydrogenase 81 2e-15
At3g47350 [Q] KOG1205 Predicted dehydrogenase 81 2e-15
At3g29250 [R] KOG0725 Reductases with broad range of substrate s... 81 2e-15
7296706_2 [R] KOG0725 Reductases with broad range of substrate s... 81 2e-15
At4g13180 [R] KOG0725 Reductases with broad range of substrate s... 80 2e-15
YNL202w [R] KOG0725 Reductases with broad range of substrate spe... 80 3e-15
CE03127 [Q] KOG1199 Short-chain alcohol dehydrogenase/3-hydroxya... 80 4e-15
Hs5031737 [R] KOG0725 Reductases with broad range of substrate s... 79 9e-15
CE02370 [R] KOG0725 Reductases with broad range of substrate spe... 78 2e-14
7293189 [I] KOG1206 Peroxisomal multifunctional beta-oxidation p... 78 2e-14
CE12594 [R] KOG0725 Reductases with broad range of substrate spe... 77 4e-14
CE03951 [R] KOG0725 Reductases with broad range of substrate spe... 77 4e-14
CE14538 [R] KOG0725 Reductases with broad range of substrate spe... 76 6e-14
Hs4758504 [Q] KOG1199 Short-chain alcohol dehydrogenase/3-hydrox... 75 8e-14
Hs10190704 [R] KOG0725 Reductases with broad range of substrate ... 75 1e-13
Hs10047132 [R] KOG0725 Reductases with broad range of substrate ... 75 1e-13
CE05526 [R] KOG0725 Reductases with broad range of substrate spe... 75 1e-13
7294452 [Q] KOG1205 Predicted dehydrogenase 75 1e-13
Hs14754051 [R] KOG0725 Reductases with broad range of substrate ... 75 1e-13
SPAC4H3.08 [R] KOG0725 Reductases with broad range of substrate ... 74 2e-13
CE05752 [R] KOG0725 Reductases with broad range of substrate spe... 74 2e-13
7292613 [Q] KOG1205 Predicted dehydrogenase 74 2e-13
Hs20149619 [Q] KOG1205 Predicted dehydrogenase 74 2e-13
CE23899 [R] KOG0725 Reductases with broad range of substrate spe... 74 2e-13
At3g47360 [Q] KOG1205 Predicted dehydrogenase 74 2e-13
YKR009c [I] KOG1206 Peroxisomal multifunctional beta-oxidation p... 74 3e-13
CE05726 [R] KOG0725 Reductases with broad range of substrate spe... 73 4e-13
7295621 [Q] KOG1205 Predicted dehydrogenase 73 4e-13
CE12990 [R] KOG0725 Reductases with broad range of substrate spe... 72 7e-13
7290988 [Q] KOG1205 Predicted dehydrogenase 72 7e-13
SPBC30D10.05c [Q] KOG1204 Predicted dehydrogenase 72 9e-13
Hs14249446 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-AC... 72 9e-13
7293522 [Q] KOG1207 Diacetyl reductase/L-xylulose reductase 71 2e-12
At5g04900 [R] KOG0725 Reductases with broad range of substrate s... 70 3e-12
7293420 [Q] KOG1199 Short-chain alcohol dehydrogenase/3-hydroxya... 70 3e-12
7297069 [Q] KOG1205 Predicted dehydrogenase 69 6e-12
CE21093 [R] KOG0725 Reductases with broad range of substrate spe... 69 1e-11
CE20725 [R] KOG0725 Reductases with broad range of substrate spe... 68 2e-11
7301818 [Q] KOG1205 Predicted dehydrogenase 67 2e-11
CE03954 [R] KOG0725 Reductases with broad range of substrate spe... 66 5e-11
At1g49670_1 [IR] KOG4169 15-hydroxyprostaglandin dehydrogenase a... 66 5e-11
At5g50690 [Q] KOG1205 Predicted dehydrogenase 66 6e-11
At5g50590 [Q] KOG1205 Predicted dehydrogenase 66 6e-11
At4g10020 [Q] KOG1205 Predicted dehydrogenase 66 6e-11
CE06649 [R] KOG0725 Reductases with broad range of substrate spe... 65 8e-11
CE03132 [R] KOG0725 Reductases with broad range of substrate spe... 65 8e-11
CE15574 [R] KOG0725 Reductases with broad range of substrate spe... 65 1e-10
SPAC521.03 [Q] KOG1205 Predicted dehydrogenase 64 2e-10
CE28758 [R] KOG0725 Reductases with broad range of substrate spe... 64 2e-10
At1g52340 [R] KOG0725 Reductases with broad range of substrate s... 64 2e-10
CE27260 [R] KOG0725 Reductases with broad range of substrate spe... 63 4e-10
CE06316 [Q] KOG1207 Diacetyl reductase/L-xylulose reductase 63 5e-10
At5g10050 [Q] KOG1209 1-Acyl dihydroxyacetone phosphate reductas... 63 5e-10
CE06423 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 62 7e-10
7292690 [Q] KOG1205 Predicted dehydrogenase 62 7e-10
7300944 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 62 9e-10
7295622 [Q] KOG1205 Predicted dehydrogenase 62 1e-09
CE27259 [R] KOG0725 Reductases with broad range of substrate spe... 60 3e-09
At3g03330 [Q] KOG1205 Predicted dehydrogenase 60 3e-09
At3g06060 [Q] KOG1210 Predicted 3-ketosphinganine reductase 60 5e-09
YIR036c [Q] KOG1204 Predicted dehydrogenase 59 6e-09
7298352 [I] KOG1014 17 beta-hydroxysteroid dehydrogenase type 3 ... 59 6e-09
YIL124w [Q] KOG1209 1-Acyl dihydroxyacetone phosphate reductase ... 59 8e-09
YMR226c [Q] KOG1205 Predicted dehydrogenase 59 1e-08
Hs7705905 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 59 1e-08
SPAC3G9.02 [R] KOG0725 Reductases with broad range of substrate ... 58 1e-08
YIR035c [Q] KOG1204 Predicted dehydrogenase 58 2e-08
CE26900 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 58 2e-08
7294126 [IR] KOG4169 15-hydroxyprostaglandin dehydrogenase and r... 58 2e-08
CE26808_2 [R] KOG0725 Reductases with broad range of substrate s... 58 2e-08
7300947 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 57 2e-08
7300731 [Q] KOG1205 Predicted dehydrogenase 57 2e-08
Hs7706318 [Q] KOG1205 Predicted dehydrogenase 57 3e-08
Hs19923983 [R] KOG0725 Reductases with broad range of substrate ... 56 5e-08
7290386 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP r... 56 5e-08
Hs20475206 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 56 7e-08
Hs7705925 [Q] KOG1207 Diacetyl reductase/L-xylulose reductase 55 9e-08
7300387 [Q] KOG1208 Dehydrogenases with different specificities ... 55 9e-08
At3g61220 [Q] KOG1208 Dehydrogenases with different specificitie... 55 1e-07
At3g12790 [R] KOG0725 Reductases with broad range of substrate s... 55 1e-07
7295674 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 55 1e-07
7290849 [I] KOG1014 17 beta-hydroxysteroid dehydrogenase type 3 ... 54 2e-07
SPCC162.03 [Q] KOG1205 Predicted dehydrogenase 54 2e-07
At2g07640 [R] KOG0725 Reductases with broad range of substrate s... 54 2e-07
7301303 [Q] KOG1210 Predicted 3-ketosphinganine reductase 54 2e-07
CE11498 [R] KOG0725 Reductases with broad range of substrate spe... 54 3e-07
SPAC977.08 [Q] KOG1205 Predicted dehydrogenase 53 4e-07
SPAC1348.09 [Q] KOG1205 Predicted dehydrogenase 53 4e-07
Hs19923850 [I] KOG1014 17 beta-hydroxysteroid dehydrogenase type... 53 6e-07
7296047 [Q] KOG1205 Predicted dehydrogenase 53 6e-07
CE13008 [R] KOG0725 Reductases with broad range of substrate spe... 52 7e-07
CE02490_1 [R] KOG0725 Reductases with broad range of substrate s... 52 9e-07
At5g61830 [Q] KOG1208 Dehydrogenases with different specificitie... 52 1e-06
SPAC23D3.11 [Q] KOG1209 1-Acyl dihydroxyacetone phosphate reduct... 51 2e-06
CE21514 [R] KOG0725 Reductases with broad range of substrate spe... 51 2e-06
7300831 [Q] KOG1205 Predicted dehydrogenase 50 4e-06
YDL114w [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 50 5e-06
At2g24190 [Q] KOG1208 Dehydrogenases with different specificitie... 50 5e-06
Hs20373187 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 49 6e-06
CE07544 [Q] KOG1205 Predicted dehydrogenase 49 6e-06
CE07539 [Q] KOG1205 Predicted dehydrogenase 49 6e-06
CE28011 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11 49 8e-06
>SPAC8E11.10 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 255
Score = 252 bits (643), Expect = 5e-67
Identities = 126/255 (49%), Positives = 167/255 (65%), Gaps = 6/255 (2%)
Query: 25 LFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVA 84
+FSLKGK ++TG S GIG+++A+ A AG+++ + Y N +E A EL K+ V+ A
Sbjct: 4 MFSLKGKTTLITGGSGGIGFSIAKAFAAAGSNVGLLYGRNKKALEYAAELRDKHGVQAKA 63
Query: 85 YQCPVTEEAKVKKTIEDVIQEFG-KIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
Y CP+ + V +T ++E G ++DV IANAG+ L + E D W KV+
Sbjct: 64 YSCPIENRSAVIETTNQAVEELGGRLDVMIANAGIAIPHLSLEDKNE-----DIWTKVVG 118
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLA 203
+ NG YY A+ G FK+QG GS++ TASMSGHI N PQ A Y+A KA V H A++LA
Sbjct: 119 INLNGAYYTAQAAGHHFKKQGKGSLIFTASMSGHIANWPQQWASYHATKAAVKHLARALA 178
Query: 204 VEWAGFARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAS 263
VEWA FARVN+VSPGYI T ++ + DE+L+ KW P R GLP EL GAYLY ASDAS
Sbjct: 179 VEWAPFARVNSVSPGYIDTDLTLYADENLRKKWKEYTPQARIGLPDELPGAYLYLASDAS 238
Query: 264 TYTTGSDLLVDGAYC 278
+Y TGSD++VDG YC
Sbjct: 239 SYCTGSDIIVDGGYC 253
>SPCC1739.08c [R] KOG0725 Reductases with broad range of substrate specificities
Length = 261
Score = 197 bits (502), Expect = 1e-50
Identities = 111/261 (42%), Positives = 162/261 (61%), Gaps = 10/261 (3%)
Query: 20 SNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYN 79
++VLDLFSLKGK VV GA+ GIG+++A AQAG ++ + Y + E+A +L+ +
Sbjct: 11 AHVLDLFSLKGKNCVVFGAAKGIGFSIATAFAQAGGNVIITYLTTDP-TEKAKKLAEETG 69
Query: 80 VKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWN 139
V+V + ++ V+ +E++ + F +I V +ANAG+P+ + L + E+
Sbjct: 70 VQVHTLKIDISRSDTVEAGVEEIQKIFKEIHVVVANAGMPFRRSVL------DSPPHEFE 123
Query: 140 KVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
KV++ + N VY A Y+G FK+QG G+++ TASMS IVN PQ A Y A+KA V
Sbjct: 124 KVMNINTNSVYRVAYYMGKIFKKQGFGNLIATASMSATIVNAPQHIAAYCASKAAVRQLC 183
Query: 200 KSLAVEWAGFARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFA 259
K+LAVEWA FAR+N+VSPGY AT + + + +W +P R GL EL G YLY A
Sbjct: 184 KALAVEWAEFARINSVSPGYFATDMPGY---EFLKQWEPYVPFKRLGLTPELRGTYLYLA 240
Query: 260 SDASTYTTGSDLLVDGAYCVL 280
S+AS++ TG DL+VDG Y L
Sbjct: 241 SNASSFVTGLDLIVDGGYTCL 261
>SPAC22A12.17c [R] KOG0725 Reductases with broad range of substrate specificities
Length = 261
Score = 188 bits (478), Expect = 6e-48
Identities = 107/257 (41%), Positives = 148/257 (56%), Gaps = 10/257 (3%)
Query: 21 NVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV 80
N+LDL SLKGK AVV G + GIG+A+ A+AGA+ + YN+ + A E++ V
Sbjct: 12 NILDLLSLKGKNAVVFGGARGIGHAICSVFAEAGANAFIVYNTTPG-EKAAKEIAQANGV 70
Query: 81 KVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
K +C VT +V+ ++ + F ID+ + N G+ K + E E+
Sbjct: 71 KTYTCKCDVTIPKEVEHAFAEIQKVFDTIDIVVPNNGICTGKSAIDMTYE------EFAN 124
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAK 200
I+ + GV+ A G F++QG GS+V TASMSG +VN+PQ Q YN +KAGVI K
Sbjct: 125 EINVNLLGVFNVAHNAGPIFQKQGHGSLVATASMSGVVVNVPQQQCAYNTSKAGVIQLIK 184
Query: 201 SLAVEWAGFARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFAS 260
SLAVEW FARVN VSPGY S+ +W P R GL +E+ AYLY AS
Sbjct: 185 SLAVEWRKFARVNCVSPGYTT---SDMTGGKFHKEWEPYTPFERNGLAKEIASAYLYLAS 241
Query: 261 DASTYTTGSDLLVDGAY 277
DA++Y +G++L+VDG Y
Sbjct: 242 DAASYASGTNLIVDGGY 258
>At2g29170 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 268
Score = 117 bits (294), Expect = 1e-26
Identities = 85/256 (33%), Positives = 133/256 (51%), Gaps = 12/256 (4%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL G A+VTG S G+G AV E LA GA + + L E E AK +V
Sbjct: 14 WSLGGMTALVTGGSKGLGEAVVEELAMLGARVHTCARNETQLQECVREWQAK-GFEVTTS 72
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V+ + +K +E+V F GK+++ + NAG TK A+ +++ ++ T
Sbjct: 73 VCDVSSRDQREKLMENVASIFQGKLNILVNNAGTGITKPTTEYTAQ------DYSFLMAT 126
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ + ++ ++ K GSGS+V+ +S +G +V+I + + Y A K + AK+LA
Sbjct: 127 NLDSAFHLSQLAHPLLKASGSGSIVLMSSTAG-VVHI-NVGSIYGATKGAMNQLAKNLAC 184
Query: 205 EWA-GFARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAS 263
EWA RVN+V P +IATP+ DE+LK + PMGR G E+ + A+
Sbjct: 185 EWARDNIRVNSVCPWFIATPLY-LNDEELKKEVERKTPMGRVGNANEVSSLVAFLCFPAA 243
Query: 264 TYTTGSDLLVDGAYCV 279
+Y TG + VDG + V
Sbjct: 244 SYITGQTICVDGGFTV 259
>At1g24360 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP reductase
Length = 308
Score = 117 bits (292), Expect = 2e-26
Identities = 85/271 (31%), Positives = 137/271 (50%), Gaps = 27/271 (9%)
Query: 11 TPQEPPKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVER 70
T Q P ++ V + V V+TGAS GIG A+A L +AG + V Y +A E
Sbjct: 63 TEQSPGEVVQKV------ESPVVVITGASRGIGKAIALALGKAGCKVLVNYARSAKEAEE 116
Query: 71 AVELSAKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAE 130
+ +Y + + + V++ V ++ + ++G IDV + NAG+ T+ L+ +
Sbjct: 117 VAKQIEEYGGQAITFGGDVSKATDVDAMMKTALDKWGTIDVVVNNAGI--TRDTLLIRMK 174
Query: 131 SGTDTDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNA 190
+W++VI + GV+ C + G ++ +S+ G I NI QA Y A
Sbjct: 175 Q----SQWDEVIALNLTGVFLCTQ-----------GRIINISSVVGLIGNIG--QANYAA 217
Query: 191 AKAGVIHFAKSLAVEWAG-FARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQ 249
AK GVI F+K+ A E A VN V PG+IA+ ++ + ED++ K IP+GR G +
Sbjct: 218 AKGGVISFSKTAAREGASRNINVNVVCPGFIASDMTAELGEDMEKKILGTIPLGRYGKAE 277
Query: 250 ELVGAYLYFA-SDASTYTTGSDLLVDGAYCV 279
E+ G + A S A++Y TG +DG +
Sbjct: 278 EVAGLVEFLALSPAASYITGQAFTIDGGIAI 308
>7295487 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 317
Score = 115 bits (288), Expect = 7e-26
Identities = 76/251 (30%), Positives = 130/251 (51%), Gaps = 11/251 (4%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L GKVAVVT ++ GIG+A+A+ LA+ GA++ + + V+ A+ K N+ V +C
Sbjct: 69 LAGKVAVVTASTDGIGFAIAKRLAEDGAAVVI-SSRKQKNVDSALAELRKLNLNVHGLKC 127
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V+E K+ E+ I +FGK+++ ++NA G ++E D W+K+ +
Sbjct: 128 HVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLEC-----DEKVWDKIFDVNVK 182
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
Y AK ++Q + S+V +S++G+ + +L Y+ +K +I K+ A + A
Sbjct: 183 SSYLLAKEALPLLRQQKNSSIVFVSSIAGY--DAFELLGAYSVSKTALIGLTKAAAKDLA 240
Query: 208 GFA-RVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAST 264
RVN ++PG I T S + +E S IPMGR G +E+ G + S+ +
Sbjct: 241 PEGIRVNCLAPGVIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAG 300
Query: 265 YTTGSDLLVDG 275
Y TG ++ G
Sbjct: 301 YITGESIVAGG 311
>At2g29350 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 269
Score = 115 bits (287), Expect = 9e-26
Identities = 85/260 (32%), Positives = 128/260 (48%), Gaps = 18/260 (6%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL G A+VTG S GIG AV E LA GA + L ER E AK +V
Sbjct: 13 WSLGGMTALVTGGSKGIGEAVVEELAMLGAKVHTCARDETQLQERLREWQAK-GFQVTTS 71
Query: 86 QCPVT---EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVI 142
C V+ + K+ +T+ + Q GK+++ + N G K AE +++ V+
Sbjct: 72 VCDVSSRDQRVKLMETVSSLYQ--GKLNILVNNVGTSIFKPTTEYTAE------DFSFVM 123
Query: 143 HTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHI-VNIPQLQACYNAAKAGVIHFAKS 201
T+ ++ ++ K GSGS+V+ +S +G + VN+ + Y A K + A++
Sbjct: 124 ATNLESAFHLSQLAHPLLKASGSGSIVLISSAAGVVHVNVGSI---YGATKGAMNQLARN 180
Query: 202 LAVEWAG-FARVNTVSPGYIATPISN-FVDEDLKNKWHSLIPMGREGLPQELVGAYLYFA 259
LA EWA R N+V P YI TP+SN F DE+ K + PMGR G E+ +
Sbjct: 181 LACEWASDNIRTNSVCPWYITTPLSNDFFDEEFKKEAVRTTPMGRVGEANEVSPLVAFLC 240
Query: 260 SDASTYTTGSDLLVDGAYCV 279
+++Y TG + VDG V
Sbjct: 241 LPSASYITGQTICVDGGATV 260
>At2g29300 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 263
Score = 114 bits (285), Expect = 2e-25
Identities = 82/258 (31%), Positives = 129/258 (49%), Gaps = 12/258 (4%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL+G A+VTGA+SGIGYA+ E LA GA + V + + L+ +++ K +V
Sbjct: 5 WSLQGMTALVTGAASGIGYAIVEELAGFGARIHV-CDISETLLNQSLREWEKKGFQVSGS 63
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C VT + +K ++ V F GK+++ + N GV K P E D++ I T
Sbjct: 64 VCDVTSRPEREKLMQTVSSLFDGKLNILVNNVGVLRAK-PTTEYV-----ADDFTFHIST 117
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ Y+ + K G GS+V +S+SG +V+I + Y K + A++LA
Sbjct: 118 NLEAAYHFCQLSHPLLKTSGYGSIVFLSSVSG-VVSITDCGSLYGLTKGALNQLARNLAC 176
Query: 205 EWA-GFARVNTVSPGYIATPISNFVDEDLKNK--WHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N V+P + T S F +D+ K S P+GR G P E+ ++
Sbjct: 177 EWAKDGIRANAVAPNVVKTAQSQFFLQDVSKKEGLFSRTPLGRSGEPNEVASLVVFLCLP 236
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + +DG V
Sbjct: 237 AASYITGQTICIDGGLTV 254
>At2g29150 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 268
Score = 114 bits (284), Expect = 2e-25
Identities = 82/258 (31%), Positives = 126/258 (48%), Gaps = 14/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL+G A+VTG S G+G AV E LA GA + L ER E AK +V
Sbjct: 14 WSLEGMTALVTGGSKGLGEAVVEELAMLGARVHTCARDETQLQERLREWQAK-GFEVTTS 72
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V+ + +K +E V F GK+++ + NAG K AE +++ ++ T
Sbjct: 73 VCDVSSREQREKLMETVSSVFQGKLNILVNNAGTGIIKPSTEYTAE------DYSFLMAT 126
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ ++ ++ K GSGS+V +S++G + + Y A+K + +SLA
Sbjct: 127 NLESAFHLSQIAHPLLKASGSGSIVFMSSVAGLVHTGASI---YGASKGAMNQLGRSLAC 183
Query: 205 EWAG-FARVNTVSPGYIATPISNFV--DEDLKNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA RVN+V P I TP+++F+ DE L+ PMGR G E+ +
Sbjct: 184 EWASDNIRVNSVCPWVITTPLTSFIFSDEKLRKAVEDKTPMGRVGEANEVSSLVAFLCFP 243
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG V
Sbjct: 244 AASYITGQTICVDGGASV 261
>At2g29370 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 268
Score = 113 bits (283), Expect = 3e-25
Identities = 80/258 (31%), Positives = 130/258 (50%), Gaps = 13/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL+G A+VTG S G+G AV E LA GA + L E E AK ++V
Sbjct: 14 WSLEGMTALVTGGSKGLGKAVVEELAMLGARVHTCARDETQLQESLREWQAK-GLQVTTS 72
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V+ + +K +E V F GK+ + + N G+ K P E +E++ +I T
Sbjct: 73 VCDVSSRDQREKLMETVSSLFQGKLSILVPNVGIGVLK-PTTECT-----AEEFSFIIAT 126
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ ++ ++ K GSG++V+ +S++G +VN+ + Y A K + A++LA
Sbjct: 127 NLESTFHFSQLAHPLLKASGSGNIVLMSSVAG-VVNLGN-TSIYGATKGAMNQLARNLAC 184
Query: 205 EWAG-FARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N+V P +I TP + D+D+K K S+ P+ R G E+ +
Sbjct: 185 EWASDNIRANSVCPWFITTPSTKDFLGDKDVKEKVESVTPLRRVGEANEVSSLVAFLCLP 244
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG + +
Sbjct: 245 AASYITGQTICVDGGFTI 262
>At2g29340 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 262
Score = 112 bits (281), Expect = 4e-25
Identities = 85/258 (32%), Positives = 128/258 (48%), Gaps = 13/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SLKG A+VTG +SGIGYA+ E LA GA + V S A L + E K +V
Sbjct: 5 WSLKGMTALVTGGASGIGYAIVEELAGFGARIHVCDISEAKLNQSLSEWEKK-GFQVSGS 63
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V + ++ ++ V +F GK+++ ++N GV +K P E E D++ I +
Sbjct: 64 VCDVASRPEREELMQTVSSQFDGKLNILVSNVGVIRSK-PTTEYTE-----DDFAFHISS 117
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ Y+ ++ K G GS++ +S++G I + Y K +I AK+LA
Sbjct: 118 NVEAAYHFSQLSHPLLKASGYGSIIFVSSIAGVISF--DAGSIYGLTKGALIQLAKNLAC 175
Query: 205 EWA-GFARVNTVSPGYIATPISNFVDEDL--KNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N V+P I TP+S ED+ K S P+GR G P E+ +
Sbjct: 176 EWAKDGIRANAVAPNVINTPLSQSYLEDVSFKKALLSRTPLGRVGEPNEVASLVAFLCLP 235
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG V
Sbjct: 236 AASYITGQTICVDGGLTV 253
>CE19894 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 260
Score = 111 bits (278), Expect = 1e-24
Identities = 77/254 (30%), Positives = 128/254 (50%), Gaps = 15/254 (5%)
Query: 29 KGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVE-LSAKYNVKVVAYQC 87
+GKVA+VT A+ GIG A+AE L GAS+ + + N V+ A+E L K KV
Sbjct: 9 EGKVAIVTAATKGIGLAIAERLLDEGASVVIG-SRNQKNVDEAIEYLKNKGLTKVAGIAG 67
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
+ KK ++ +Q+FGKI++ + N G+ G ++E ++ W+K+ +
Sbjct: 68 HIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSD-----QVWDKLFEVNVK 122
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
+ K V ++G G+++ AS S + P A Y K ++ ++LA+ A
Sbjct: 123 AGFQMTKLVHPHIAKEGGGAIIFNASYSAY--KSPPGIAAYGVTKTTLVGLTRALAMGLA 180
Query: 208 -GFARVNTVSPGYIATPISNFV---DEDLKNKWHSL--IPMGREGLPQELVGAYLYFASD 261
RVN ++PG I T +S + ED + + + I +GR G+P + G Y ASD
Sbjct: 181 KDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASD 240
Query: 262 ASTYTTGSDLLVDG 275
S+Y TG +++ G
Sbjct: 241 DSSYITGEMIIIAG 254
>Hs19923817 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 303
Score = 110 bits (276), Expect = 2e-24
Identities = 78/259 (30%), Positives = 128/259 (49%), Gaps = 22/259 (8%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKY----NVKVV 83
L+G+VA+VTG ++GIG A+ + L + G+++ + L A EL A +V+
Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 84 AYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
QC + E +V ++ + FGKI+ + N G G + AE + W+ V+
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-----GQFLSPAEH-ISSKGWHAVLE 129
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMV--ITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
T+ G +Y K V + + ++ GS+V I + +G L AA+AGV + KS
Sbjct: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGF-----PLAVHSGAARAGVYNLTKS 184
Query: 202 LAVEWA-GFARVNTVSPG--YIATPISNFVD--EDLKNKWHSLIPMGREGLPQELVGAYL 256
LA+EWA R+N V+PG Y T + N+ + IP R G+P+E+
Sbjct: 185 LALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244
Query: 257 YFASDASTYTTGSDLLVDG 275
+ S A+++ TG + VDG
Sbjct: 245 FLLSPAASFITGQSVDVDG 263
>At2g29320 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 269
Score = 108 bits (269), Expect = 1e-23
Identities = 83/259 (32%), Positives = 126/259 (48%), Gaps = 12/259 (4%)
Query: 25 LFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVA 84
L+SL+G A+VTGA+SGIGYA+ E LA GA + + S L + E K +V
Sbjct: 10 LWSLQGMTALVTGAASGIGYAIVEELAGFGAKIHICDISKTLLNQSLSEWENK-GFQVSG 68
Query: 85 YQCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
C VT + +K ++ V F GK+++ + N GV K P E D++ I
Sbjct: 69 SVCDVTSHPEREKLMQTVSSIFDGKLNILVNNVGVLRGK-PTTEYV-----ADDFTFHIS 122
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLA 203
T+ Y+ + K G GS+V +S++G +V++ + Y K + A++LA
Sbjct: 123 TNLEAAYHFCQLSHPLLKASGYGSIVFLSSVAG-VVSLIDCGSIYGLTKGALNQLARNLA 181
Query: 204 VEWA-GFARVNTVSPGYIATPISNFVDEDLKNK--WHSLIPMGREGLPQELVGAYLYFAS 260
EWA R N V+P + T S ED+ K S P+GR G P E+ ++
Sbjct: 182 CEWAKDGIRANAVAPNVVKTAQSQSFLEDVSKKEGLLSRTPLGRVGEPNEVSSLVVFLCL 241
Query: 261 DASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG V
Sbjct: 242 PAASYITGQTICVDGGLTV 260
>At2g29310 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 262
Score = 106 bits (265), Expect = 3e-23
Identities = 79/258 (30%), Positives = 127/258 (48%), Gaps = 13/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL+G A+VTGA+SGIGYA+ E LA GA + + S L + E K +V
Sbjct: 5 WSLQGMTALVTGAASGIGYAIVEELASFGAIIHICDISETLLSQSLSEWEKK-GFQVSGS 63
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V +K ++ V F GK+++ + N GV K AE +++ I T
Sbjct: 64 ICDVASRPDREKLMQTVSSLFDGKLNILVNNVGVIRGKPTTEYVAE------DFSYHIST 117
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ ++ ++ K G GS+V +S +G +V++ Q + Y+ K + ++LA
Sbjct: 118 NLEPAFHFSQLSHLLLKASGFGSIVFMSSATG-VVSV-QCGSIYSLTKGALNQLTRNLAC 175
Query: 205 EWA-GFARVNTVSPGYIATPISNFVDEDL--KNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N V+P + TP+S ED+ K S P+GR G P E+ ++
Sbjct: 176 EWAKDGIRANAVAPNVVKTPLSQSYLEDVGFKEALFSRTPLGRAGEPNEVASLVVFLCLP 235
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + +DG + V
Sbjct: 236 AASYITGQTICIDGGFTV 253
>At2g29360 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 271
Score = 106 bits (264), Expect = 4e-23
Identities = 79/258 (30%), Positives = 126/258 (48%), Gaps = 13/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL G A+VTG S GIG AV E LA GA + L E + AK +V
Sbjct: 14 WSLVGMTALVTGGSKGIGEAVVEELATLGARIHTCARDETQLQESLRKWQAK-GFQVTTS 72
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V+ K +K +E V F GK+++ + N G K L AE +++ + T
Sbjct: 73 VCDVSSRDKREKLMETVSTIFEGKLNILVNNVGTCIVKPTLQHTAE------DFSFTMAT 126
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ ++ ++ K GSGS+V+ +S+SG +V++ + Y +K + ++LA
Sbjct: 127 NLESAFHLSQLAHPLLKASGSGSIVLISSVSG-VVHV-NGASIYGVSKGAMNQLGRNLAC 184
Query: 205 EWAG-FARVNTVSPGYIATPI--SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N+V P +I TP+ + +E+ + + S PMGR G E+ +
Sbjct: 185 EWASDNIRTNSVCPWFIETPLVTESLSNEEFRKEVESRPPMGRVGEVNEVSSLVAFLCLP 244
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG + V
Sbjct: 245 AASYITGQTICVDGGFTV 262
>At1g63380 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 287
Score = 105 bits (261), Expect = 9e-23
Identities = 80/259 (30%), Positives = 133/259 (50%), Gaps = 21/259 (8%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYN------VK 81
LK KV +VTGASSGIG + L +AG + + A V+R L ++ N V+
Sbjct: 22 LKDKVVLVTGASSGIGREICLDLCKAGCKIV----AAARRVDRLNSLCSEINSFGAIGVQ 77
Query: 82 VVAYQCPVTEEA-KVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
VA + V+ EA ++K +++ + FGKIDV I NAG+ ++ +E +EW+K
Sbjct: 78 AVALELDVSSEADTIRKAVKEAWETFGKIDVLINNAGIRGNVKSSLDLSE-----EEWDK 132
Query: 141 VIHTDFNGVYYCAKYVGAQFK-RQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
V T+ G + +KYV + + GS++ +S+SG + + Y +K GV
Sbjct: 133 VFRTNLTGSWLISKYVCLLMRDAERGGSVINVSSISGLHRGLLRGGLAYACSKGGVDTMT 192
Query: 200 KSLAVEWAGF-ARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMG-REGLPQELVGAY 255
+ +A+E A + RVN+++PG + I+ F E LK ++P+ ++ + L
Sbjct: 193 RMMAIELAVYKIRVNSIAPGIFRSEITQGLFQKEWLKKVTEKVVPLKMQQTVDPGLTSLV 252
Query: 256 LYFASDASTYTTGSDLLVD 274
Y D+S Y TG+ +VD
Sbjct: 253 RYLIHDSSQYVTGNTYIVD 271
>At1g07440 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 266
Score = 104 bits (259), Expect = 2e-22
Identities = 77/257 (29%), Positives = 125/257 (47%), Gaps = 12/257 (4%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SLK K +VTG + GIG+A+ E A GA + + L E + K +V
Sbjct: 10 WSLKAKTVLVTGGTKGIGHAIVEEFAGFGAVIHTCARNEYELNE-CLSKWQKKGFQVTGS 68
Query: 86 QCPVTEEAKVKKTIEDVIQEFG-KIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C + + +K ++ V FG K+D+ I N G +K L AE +++ I T
Sbjct: 69 VCDASLRPEREKLMQTVSSMFGGKLDILINNLGAIRSKPTLDYTAE------DFSFHIST 122
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ Y+ ++ K G G+++ +S++G V + + Y+A K + A++LA
Sbjct: 123 NLESAYHLSQLAHPLLKASGCGNIIFMSSIAG--VVSASVGSIYSATKGALNQLARNLAC 180
Query: 205 EWAGFA-RVNTVSPGYIATPISNFV-DEDLKNKWHSLIPMGREGLPQELVGAYLYFASDA 262
EWA R N V+P IATP++ V D++ K S P+GR G P+E+ + A
Sbjct: 181 EWASDGIRANAVAPAVIATPLAEAVYDDEFKKVVISRKPLGRFGEPEEVSSLVAFLCMPA 240
Query: 263 STYTTGSDLLVDGAYCV 279
++Y TG + VDG V
Sbjct: 241 ASYITGQTICVDGGLTV 257
>CE09969 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 257
Score = 102 bits (254), Expect = 6e-22
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 13/252 (5%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L +VA+VT ++ GIG+A+A+ L AGAS+ V V+ AV N+
Sbjct: 9 LTDRVALVTASTKGIGFAIAKQLGAAGASVVVCSRKKEN-VDEAVAALRLENIDAHGTTA 67
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V ++ K I+ + F K+D+ ++NA V G L++ +S +W+K++ +
Sbjct: 68 HVGNKSDRTKLIDFTLDRFTKLDILVSNAAVNPHYGDLMKVTDS-----QWDKLLDLNVK 122
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQ-ACYNAAKAGVIHFAKSLAVEW 206
+ K + G G++V +S++G+ P + Y+ K + +KSLA+
Sbjct: 123 SAFELTKEAVPHLEASGRGNVVFVSSVAGYS---PMNEIGAYSVMKTTLTGLSKSLALNL 179
Query: 207 AGF-ARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAS 263
A RVN+++PG I T S F DE K KW S I R G P E A + SD +
Sbjct: 180 ARRNIRVNSIAPGIIQTDFSQVLFSDESEKQKWLSQIAQRRFGDPDECAEAVAFLVSDEA 239
Query: 264 TYTTGSDLLVDG 275
+Y +G + ++G
Sbjct: 240 SYISGETIGING 251
>CE04339 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP reductase
Length = 255
Score = 100 bits (249), Expect = 2e-21
Identities = 82/254 (32%), Positives = 130/254 (50%), Gaps = 18/254 (7%)
Query: 29 KGKVAVVTGASSGIGYAVAEGLAQAGASLAV--WYNSNAALVERAVELSAKYNVKVVAYQ 86
K K + +G +SGIG A+++ LA+ GA + V + NAA +A+ S ++ ++
Sbjct: 13 KTKKSQFSGGASGIGKAISQTLAKHGARVVVADLDSGNAAATAKALPASQSHS----SFA 68
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
C V+ VK E V + G + + AG+ TK + + ++W+ VI +
Sbjct: 69 CDVSNADSVKGLSEHV-KSLGTPSILVNCAGI--TKDSTLLKMKQ----EQWDSVIKVNL 121
Query: 147 NGVYYCAK-YVGAQFKRQGSG-SMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
GV++ ++ +V A S++ +S+ G + N Q Y A KAGVI F KS A
Sbjct: 122 TGVFHVSQAFVKASVDNNNHPLSIINVSSIVGKMGNFGQTN--YAATKAGVIGFTKSAAK 179
Query: 205 EWAGF-ARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAS 263
E A RVN V PG+I TP++ + + + IPMGR G +E+ + LY ASD S
Sbjct: 180 ELAKKNVRVNAVLPGFIKTPMTEAMPPTVLAEICKGIPMGRMGEAEEIANSVLYLASDLS 239
Query: 264 TYTTGSDLLVDGAY 277
+Y TG+ L V G +
Sbjct: 240 SYVTGATLEVTGGF 253
>At2g30670 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 262
Score = 100 bits (249), Expect = 2e-21
Identities = 75/258 (29%), Positives = 133/258 (51%), Gaps = 13/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL+G A+VTG +SGIG+A+ E LA GA + V + + L+ +++ K +V
Sbjct: 5 WSLQGMTALVTGGASGIGHAIVEELAGLGARIYV-CDISETLLNQSLSEWEKKGFQVSGS 63
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V+ ++ + ++ V + F GK+++ + N GV K P +E + +++ I T
Sbjct: 64 ICDVSSHSERETLMQTVSKMFDGKLNILVNNVGVVNPK-PTIEYVAA-----DFSFSIST 117
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ Y+ ++ K GS++ +S+ G +V++ + + Y+ K + AK+LA
Sbjct: 118 NLESAYHLSQLSHPLLKASEFGSIIFISSVGG-VVSM-ECGSIYSLTKGALNQLAKTLAC 175
Query: 205 EWA-GFARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N+V+P +I T ++ F D D + S P+GR G P E+ +
Sbjct: 176 EWARDGIRANSVAPNFIYTAMAQPFFKDADYEKSLVSRTPLGRAGEPNEVSSLVAFLCLP 235
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG V
Sbjct: 236 AASYITGQTICVDGGLTV 253
>CE19130 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP reductase
Length = 296
Score = 100 bits (248), Expect = 3e-21
Identities = 77/250 (30%), Positives = 126/250 (49%), Gaps = 13/250 (5%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L K+A+VTG SGIG A+ + A +GA L V +A A L + A++
Sbjct: 54 LSSKLAIVTGGGSGIGQAICKKFAASGARLIVADLKKSAAEATAGNLPGNGHS---AFEI 110
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V++ V + +++ I+ G+ + N L++ +++ +W V++ + N
Sbjct: 111 DVSDPEHVAR-LQEFIKSSGESPSVLVNCAGITKDATLLKMSQN-----QWQDVMNVNLN 164
Query: 148 GVYYCAKYVGAQFKRQGSG-SMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
V+ ++ + + GS S+V +S+ G I N Q Y A K+GVI F KS A E
Sbjct: 165 SVFLMSQMIARESVAAGSPLSIVNVSSIVGKIGNFGQTN--YAATKSGVIGFTKSAAREL 222
Query: 207 AGF-ARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDASTY 265
A RVN V PG+I TP++ + + + S++P R G +E+ A L+ ASD S+Y
Sbjct: 223 ATKNIRVNAVLPGFIRTPMTEAMPPKVLDAMVSMVPQRRLGETEEIANAVLFLASDMSSY 282
Query: 266 TTGSDLLVDG 275
TG+ L V G
Sbjct: 283 VTGTTLEVTG 292
>At2g29260 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 322
Score = 100 bits (248), Expect = 3e-21
Identities = 78/261 (29%), Positives = 130/261 (48%), Gaps = 19/261 (7%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL G A+VTG + GIG A+ E LA GA + + L E + + +V
Sbjct: 66 WSLNGMSALVTGGTRGIGRAIVEELAGLGAEVHTCARNEYEL-ENCLSDWNRSGFRVAGS 124
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V++ ++ + +E V F GK+ + + N G K P+VE E++ ++ T
Sbjct: 125 VCDVSDRSQREALMETVSSVFEGKLHILVNNVGTNIRK-PMVEFTAG-----EFSTLMST 178
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+F V++ + + +GS+V +S+SG V++ + ++ K + +SLA
Sbjct: 179 NFESVFHLCQLAYPLLRESKAGSVVFISSVSG-FVSLKNMSV-QSSTKGAINQLTRSLAC 236
Query: 205 EWA-GFARVNTVSPGYIATPISNFVDEDLKNKWH-----SLIPMGREGLPQELVGAYLYF 258
EWA R+N V+P YI T + V++ L NK + S+ P+GR G P+E+ A +
Sbjct: 237 EWAKDNIRINAVAPWYIKT---SMVEQVLSNKEYLEEVYSVTPLGRLGEPREVSSAVAFL 293
Query: 259 ASDASTYTTGSDLLVDGAYCV 279
AS+Y TG L VDG +
Sbjct: 294 CLPASSYITGQILCVDGGMSI 314
>At2g29290 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 262
Score = 99.8 bits (247), Expect = 4e-21
Identities = 79/258 (30%), Positives = 128/258 (48%), Gaps = 13/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL+G A+VTG + GIG AV E L+ GA + L ER E K +V
Sbjct: 5 WSLQGMNALVTGGTKGIGEAVVEELSILGARVHTCARDETQLQERLREWQEK-GFQVTTS 63
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C V+ + +K +E V F GK+++ + N G K AE E++ ++ T
Sbjct: 64 ICDVSLREQREKLMETVSSLFQGKLNILVNNVGTLMLKPTTEYTAE------EFSFLMAT 117
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ + ++ ++ K GSGS+V+ +S++G +V++ + + Y A K + A++LA
Sbjct: 118 NLDSAFHISQLAHPLLKASGSGSIVLMSSIAG-VVHV-GVGSIYGATKGAMNQLARNLAC 175
Query: 205 EWAG-FARVNTVSPGYIATP-ISNFVD-EDLKNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N + P I TP IS+ + E++K + PMGR G E+ +
Sbjct: 176 EWASDNIRTNAICPWLITTPLISDLLSVEEMKKEAEERTPMGRVGEANEVSPLVAFLCLP 235
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG V
Sbjct: 236 AASYITGQVICVDGGLTV 253
>At4g05530 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 254
Score = 99.0 bits (245), Expect = 7e-21
Identities = 68/251 (27%), Positives = 120/251 (47%), Gaps = 14/251 (5%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L+GKVA+VT ++ GIG+ + E GAS+ V A + E +L +K + C
Sbjct: 9 LEGKVAIVTASTQGIGFGITERFGLEGASVVVSSRKQANVDEAVAKLKSK-GIDAYGIVC 67
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V+ + +E +Q++GKID+ + NA + P++ + E+ D W + +
Sbjct: 68 HVSNAQHRRNLVEKTVQKYGKIDIVVCNAAANPSTDPILSSKEAVLD-KLWEINVKSSIL 126
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQ-LQACYNAAKAGVIHFAKSLAVEW 206
+ A ++ + S++ S++G PQ A Y K ++ K+LA E
Sbjct: 127 LLQDMAPHL------EKGSSVIFITSIAGF---SPQGAMAMYGVTKTALLGLTKALAAEM 177
Query: 207 AGFARVNTVSPGYIATPISNFV--DEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAST 264
A RVN V+PG++ T ++F+ +++ + R G ++ A + ASD S+
Sbjct: 178 APDTRVNAVAPGFVPTHFASFITGSSEVREGIEEKTLLNRLGTTGDMAAAAAFLASDDSS 237
Query: 265 YTTGSDLLVDG 275
Y TG L+V G
Sbjct: 238 YITGETLVVAG 248
>7296705 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 257
Score = 98.2 bits (243), Expect = 1e-20
Identities = 77/256 (30%), Positives = 134/256 (52%), Gaps = 16/256 (6%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
S K KV +VTGASSGIG + LA+ G L + + L E A ++ A +
Sbjct: 3 SFKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVA 62
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
+ E+ V+ + + + G+IDV + NAG+ L + T +++++V++T+
Sbjct: 63 ADINSESDVQGIVSATLAKHGRIDVLVNNAGI------LELGSIENTSLEQFDRVMNTNV 116
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
+Y V + + G++V +S++G I + P + A YN +KA V F + +A+E
Sbjct: 117 RSLYQLTHLVTPELIKT-KGNIVNVSSVNG-IRSFPGVLA-YNVSKAAVDQFTRCVALEL 173
Query: 207 A-GFARVNTVSPGYIATPIS--NFVDEDLKNKW--HSLI--PMGREGLPQELVGAYLYFA 259
A RVN+V+PG I T + +D++ K+ H+ + +GR G +E+ A + A
Sbjct: 174 APKGVRVNSVNPGVIITELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLA 233
Query: 260 SDASTYTTGSDLLVDG 275
SD ++++TG L VDG
Sbjct: 234 SDEASFSTGISLPVDG 249
>SPAC922.06 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 258
Score = 97.1 bits (240), Expect = 3e-20
Identities = 74/255 (29%), Positives = 127/255 (49%), Gaps = 26/255 (10%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
+++G+V ++TGA+ GIG + + + G +A +V+ +K +A Q
Sbjct: 2 TVEGRVVLITGAAGGIGKVLCKMFTELGDRVA-----GIDIVD-----PSKVQDAALALQ 51
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
V++ +++ IE VIQ G IDV I NAG+ P + + + W+ +
Sbjct: 52 ADVSKADQIETAIEKVIQTLGPIDVLINNAGLA-DDTPFEQLSH-----ESWDHDVSLVL 105
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVIT-ASMSGHI-VNIPQLQACYNAAKAGVIHFAKSLAV 204
G Y +YV +QG G ++ S++GHI + P Y+AAKAG+ + K+LAV
Sbjct: 106 RGNYLTQRYVIPHMAKQGKGGSIVNIGSVNGHIYLGSP----AYSAAKAGLENLTKALAV 161
Query: 205 EWAGFA-RVNTVSPGYIATPI--SNFVDE-DLKNKWHSLIPMGREGLPQELVGAYLYFAS 260
+ RVN +PG I +P F D+ ++ P+GR G P+++ A ++ A
Sbjct: 162 RYGPLGIRVNVCAPGTIWSPAWDERFKKHPDVGDRMKRWYPVGRLGTPEDVARAVIFLAD 221
Query: 261 DASTYTTGSDLLVDG 275
+++ TG+ L VDG
Sbjct: 222 SKNSFITGTTLYVDG 236
>Hs15277342 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP reductase
Length = 261
Score = 97.1 bits (240), Expect = 3e-20
Identities = 80/257 (31%), Positives = 128/257 (49%), Gaps = 17/257 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKV----- 82
L+ +A+VTGA SGIG AV+ LA GA++A AA E L + +
Sbjct: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68
Query: 83 -VAYQCPVTEEAKVKKTIEDVIQEFGKI-DVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
A+Q V+E + +E V F + V ++ AG+ + L+ +E D+W+K
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF-LLHMSE-----DDWDK 122
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGS-GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
VI + G + + G GS++ +S+ G + N+ Q Y A+KAGVI
Sbjct: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTN--YAASKAGVIGLT 180
Query: 200 KSLAVEWAGFA-RVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYF 258
++ A E R N+V PG+IATP++ V + + +K +IPMG G P+++ +
Sbjct: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240
Query: 259 ASDASTYTTGSDLLVDG 275
AS+ S Y TG+ + V G
Sbjct: 241 ASEDSGYITGTSVEVTG 257
>At5g06060 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 264
Score = 96.7 bits (239), Expect = 3e-20
Identities = 80/259 (30%), Positives = 128/259 (48%), Gaps = 15/259 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL GK A+VTG + GIG AV E LA+ GA + + L A K N VV+
Sbjct: 7 WSLAGKTALVTGGTRGIGRAVVEELAKFGAKVHTCSRNQEEL--NACLNDWKANGLVVSG 64
Query: 86 Q-CPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
C + + +K I++ F GK+++ I N G K P VE + ++E+ K++
Sbjct: 65 SVCDASVRDQREKLIQEASSAFSGKLNILINNVGTNVRK-PTVEYS-----SEEYAKIMS 118
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLA 203
T+ ++ ++ K G GS+V +S++G +V++ + Y A K + ++LA
Sbjct: 119 TNLESAFHLSQIAHPLLKASGVGSIVFISSVAG-LVHLSS-GSIYGATKGALNQLTRNLA 176
Query: 204 VEWAG-FARVNTVSPGYIATPISNFVDE--DLKNKWHSLIPMGREGLPQELVGAYLYFAS 260
EWA R N V+P YI T + + E + S P+GR G P+E+ +
Sbjct: 177 CEWASDNIRTNCVAPWYIKTSLVETLLEKKEFVEAVVSRTPLGRVGEPEEVSSLVAFLCL 236
Query: 261 DASTYTTGSDLLVDGAYCV 279
AS+Y TG + VDG + V
Sbjct: 237 PASSYITGQVISVDGGFTV 255
>At3g55310 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 298
Score = 96.7 bits (239), Expect = 3e-20
Identities = 76/258 (29%), Positives = 125/258 (47%), Gaps = 20/258 (7%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYN------VK 81
LK KV +VTGASSGIG + LA+AG + + A V+R L ++ N ++
Sbjct: 36 LKDKVVLVTGASSGIGREICLDLAKAGCQVI----AAARRVDRLNSLCSEINSFSSTGIQ 91
Query: 82 VVAYQCPVTEEAK-VKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
A + V+ +A ++K + + FGKID I NAG+ ++ +E DEW+
Sbjct: 92 AAALELDVSSDAATIQKAVREAWDIFGKIDALINNAGIRGNVKLSLDLSE-----DEWDN 146
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAK 200
V +T+ G + AKYV + G VI S + +I Y+ +K GV ++
Sbjct: 147 VFNTNLKGPWLVAKYVCVLMRDAKRGGSVINISSVAGVRSIVPGGLAYSCSKGGVDTMSR 206
Query: 201 SLAVEWAGF-ARVNTVSPGYIATPISNFV--DEDLKNKWHSLIPMG-REGLPQELVGAYL 256
+A+E RVN+++PG + I+ + E LKN +P+ ++ + L
Sbjct: 207 MMAIELGVHKIRVNSIAPGLFKSEITQALMQKEWLKNVTERTVPLKVQQTIDPGLTSLVR 266
Query: 257 YFASDASTYTTGSDLLVD 274
Y D+S Y +G+ +VD
Sbjct: 267 YLIHDSSQYISGNTYIVD 284
>At1g62610 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 307
Score = 96.7 bits (239), Expect = 3e-20
Identities = 76/259 (29%), Positives = 132/259 (50%), Gaps = 21/259 (8%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYN------VK 81
LK KV +VTGASSGIG + L +AG + + A V+R L ++ N V+
Sbjct: 44 LKDKVVLVTGASSGIGREICLDLCKAGCKIV----AAARRVDRLNSLCSEINSFGAIGVQ 99
Query: 82 VVAYQCPVTEEA-KVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
A + V+ +A ++K +++ + FG IDV I NAG+ +G + + + +EW+K
Sbjct: 100 AAALELDVSSDADTIRKAVKEAWEIFGTIDVLINNAGI---RGNVKSSLD--LSKEEWDK 154
Query: 141 VIHTDFNGVYYCAKYVGAQFK-RQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
V T+ G + +KYV + + GS++ +S+SG + + Y +K GV
Sbjct: 155 VFRTNLTGSWLISKYVCLLMRDAKRGGSVINVSSISGLHRGLLRGGLAYACSKGGVDTMT 214
Query: 200 KSLAVEWAGF-ARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMG-REGLPQELVGAY 255
+ +A+E A + RVN+++PG + I+ F E L+ ++P+ ++ + L
Sbjct: 215 RMMAIELAVYKIRVNSIAPGIFRSEITQGLFQKEWLEKVTEKIVPLKMQQTVDPGLTSLV 274
Query: 256 LYFASDASTYTTGSDLLVD 274
Y D+S Y TG+ +VD
Sbjct: 275 RYLIHDSSQYVTGNTYIVD 293
>Hs10337605 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 260
Score = 96.3 bits (238), Expect = 4e-20
Identities = 70/251 (27%), Positives = 126/251 (49%), Gaps = 11/251 (4%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L KVA+VT ++ GIG+A+A LAQ GA + V + V++AV + V C
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVV-SSRKQQNVDQAVATLQGEGLSVTGTVC 70
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V + ++ + ++ G ID+ ++NA V G L++ E + W+K + +
Sbjct: 71 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTE-----EVWDKTLDINVK 125
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
K V + +++G GS+VI +S++ + P YN +K ++ K+LA+E A
Sbjct: 126 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPS-PGFSP-YNVSKTALLGLTKTLAIELA 183
Query: 208 -GFARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAST 264
RVN ++PG I T S ++D++ + + + R G P++ G + S+ ++
Sbjct: 184 PRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDAS 243
Query: 265 YTTGSDLLVDG 275
Y TG ++V G
Sbjct: 244 YITGETVVVGG 254
>At2g29330 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 260
Score = 95.9 bits (237), Expect = 6e-20
Identities = 72/258 (27%), Positives = 126/258 (47%), Gaps = 13/258 (5%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
+SL+G A+VTG +SGIG+A+ E LA GA + V + + L+ +++ K +V
Sbjct: 5 WSLQGLTALVTGGASGIGHAIVEELAGFGAKIHV-CDISKTLLNQSLSEWEKKGFQVSGS 63
Query: 86 QCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
C + + + ++ V F GK+++ + N G TK P +E + ++++ +I T
Sbjct: 64 VCDASNRLERETLMQTVTTIFDGKLNILVNNVGTIRTK-PTIE-----YEAEDFSFLIST 117
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ Y+ ++ K G+G + +S +G IV+ + Y K + A++LA
Sbjct: 118 NLESAYHLSQLSHPLLKASGNGIITFISSAAG-IVSF-DAASIYGLTKGALNQLARNLAC 175
Query: 205 EWA-GFARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASD 261
EWA R N V+P +I T ++ D S P+GR G P+E+ +
Sbjct: 176 EWAKDGIRANAVAPNFITTALAKPFLEDAGFNEILSSRTPLGRAGEPREVASLVAFLCLP 235
Query: 262 ASTYTTGSDLLVDGAYCV 279
A++Y TG + VDG V
Sbjct: 236 AASYITGQTICVDGGLTV 253
>At3g26760 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 269
Score = 95.1 bits (235), Expect = 1e-19
Identities = 76/263 (28%), Positives = 124/263 (46%), Gaps = 22/263 (8%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L+GKVAV+TG +SGIG A AE GA + + A A EL + + +C
Sbjct: 5 LEGKVAVITGGASGIGKATAEEFVSQGAQVIIVDIDEEAGHMVATELGSAAHF----LRC 60
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
VTEE ++ K +E + GK+DV + +AG+ + P + + D D ++KV+ +
Sbjct: 61 DVTEEEQIAKAVETAVTRHGKLDVMLNSAGISCSISP---PSIADLDMDTYDKVMRLNVR 117
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
G K+ GSGS++ +S+SG + + Y+ +K + K++A E
Sbjct: 118 GTVLGIKHAARAMIPAGSGSILCLSSISGLMGGLG--PHAYSISKFTIPGVVKTVASELC 175
Query: 208 GFA-RVNTVSPGYIATPIS------NFVDEDLKNKWHSLIPMGREGLPQE------LVGA 254
R+N +SP I TP++ F ++ + I L E + A
Sbjct: 176 KHGLRINCISPAGIPTPLTLRMFREAFAGHSIREEQLLAIVNATGELKGEKCEEIDVAKA 235
Query: 255 YLYFASDASTYTTGSDLLVDGAY 277
LY ASD + + TG +L+VDG +
Sbjct: 236 ALYLASDDAKFVTGHNLVVDGGF 258
>At1g07450 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 260
Score = 95.1 bits (235), Expect = 1e-19
Identities = 73/261 (27%), Positives = 120/261 (45%), Gaps = 14/261 (5%)
Query: 23 LDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKV 82
++ +SL+G A+VTG S GIGYA+ E L GA + + L E AK +V
Sbjct: 3 INRWSLQGMTALVTGGSKGIGYAIVEELVGFGARVHICDIDETLLNECLSGWHAK-GFEV 61
Query: 83 VAYQCPVTEEAKVKKTIEDVIQEFG-KIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKV 141
C V+ + + ++ V FG K+++ I N G K L AE +++ +
Sbjct: 62 SGSICDVSSRPQRVQLMQTVSSLFGAKLNILINNVGKYILKPTLESTAE------DFSSL 115
Query: 142 IHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
+ T+ YY ++ K G+G++V +S++G + + Y K + A+
Sbjct: 116 MATNLESAYYISQLAHPLLKASGNGNIVFISSVTGVVSGTSTI---YGVTKGALNQLARD 172
Query: 202 LAVEWAG-FARVNTVSPGYIATPI--SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYF 258
LA EWA R N+V+P AT + DE S P+GR P+E+ +
Sbjct: 173 LACEWASDNIRANSVAPWVTATSLVQKYLEDEIFAEAMFSRTPLGRACEPREVASLVTFL 232
Query: 259 ASDASTYTTGSDLLVDGAYCV 279
A++Y TG + +DG + V
Sbjct: 233 CLPAASYITGQTICIDGGFTV 253
>At3g26770 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 280
Score = 94.4 bits (233), Expect = 2e-19
Identities = 74/259 (28%), Positives = 122/259 (46%), Gaps = 20/259 (7%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L+GKVA++TG +SG+G A A + GA + + + A EL ++ +C
Sbjct: 15 LEGKVALITGGASGLGKATASEFLRHGARVVIADLDAETGTKTAKELGSEAEF----VRC 70
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
VT EA + +E ++ +GK+DV NAG+ GP+ A+ S D E+ +V+ +
Sbjct: 71 DVTVEADIAGAVEMTVERYGKLDVMYNNAGI---VGPMTPASISQLDMTEFERVMRINVF 127
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNI-PQLQACYNAAKAGVIHFAKSLAVEW 206
GV K+ SG ++ T+S++G + P G++ A S E
Sbjct: 128 GVVSGIKHAAKFMIPARSGCILCTSSVAGVTGGLAPHSYTISKFTTPGIVKSAASELCEH 187
Query: 207 AGFARVNTVSPGYIATPIS---------NFVDEDLKNKWHSLIPM-GREGLPQELVGAYL 256
R+N +SPG +ATP++ +E L+ + + G E ++ A L
Sbjct: 188 G--VRINCISPGTVATPLTLSYLQKVFPKVSEEKLRETVKGMGELKGAECEEADVAKAAL 245
Query: 257 YFASDASTYTTGSDLLVDG 275
Y AS+ Y TG +L+VDG
Sbjct: 246 YLASNDGKYVTGHNLVVDG 264
>At5g18210 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 261
Score = 94.0 bits (232), Expect = 2e-19
Identities = 70/262 (26%), Positives = 130/262 (48%), Gaps = 20/262 (7%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVER-AVELSAKYNVK---- 81
SL G+VA+VTG+S GIG A+A LA+ GA + + Y + + ++ A E+++
Sbjct: 7 SLAGRVAIVTGSSRGIGRAIAIHLAELGAKIVINYTTRSTEADQVAAEINSSAGTVPQPI 66
Query: 82 VVAYQCPVTEEAKVKKTIEDVIQEFGK-IDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
V + ++E +++K + + F + + + +AG+ P + + T +E+++
Sbjct: 67 AVVFLADISEPSQIKSLFDAAEKAFNSPVHILVNSAGILNPNYPTI----ANTPIEEFDR 122
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGSGSMV-ITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
+ + G + C K + KR G G ++ +T+S++ ++ Q Y A+KA V
Sbjct: 123 IFKVNTRGSFLCCKEAAKRLKRGGGGRIILLTSSLTEALI---PGQGAYTASKAAVEAMV 179
Query: 200 KSLAVEWAGFA-RVNTVSPGYIATPISNFVDEDLKNKWHSLI---PMGREGLPQELVGAY 255
K LA E G N VSPG +AT + F D + ++I P GR G +++
Sbjct: 180 KILAKELKGLGITANCVSPGPVATEM--FFDGKSEETVMNIIERSPFGRLGETKDIASVV 237
Query: 256 LYFASDASTYTTGSDLLVDGAY 277
+ ASD + G ++ +GA+
Sbjct: 238 GFLASDGGEWINGQVIVANGAF 259
>At3g05260 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 289
Score = 93.6 bits (231), Expect = 3e-19
Identities = 85/280 (30%), Positives = 133/280 (47%), Gaps = 24/280 (8%)
Query: 10 PTPQEPPKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVE 69
PTP+ +SN L GKVA+VTG SGIG AV A GAS+A Y +
Sbjct: 22 PTPEFS---SSNYKPSNKLHGKVALVTGGDSGIGKAVCHCYALEGASVAFTYVKGREDKD 78
Query: 70 RAVELSAKYNVKVVAYQCPVT------EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKG 123
L + VK + P+ E K+ +E+V+ FG+IDV + A
Sbjct: 79 AEETLRLLHEVKTREAKEPIMIATDLGFEENCKRVVEEVVNSFGRIDVLVNCAAEQH--- 135
Query: 124 PLVEAAESGTDTDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQ 183
E + D +V T+ ++ KY + ++GS S++ T S+ + N
Sbjct: 136 ---EVSIEDIDEARLERVFRTNIFSQFFLVKY-ALKHMKEGS-SIINTTSVVAYAGNSSL 190
Query: 184 LQACYNAAKAGVIHFAKSLAVEWAGFA-RVNTVSPGYIATPI--SNFVDEDLKNKWHSLI 240
L+ Y A K ++ F + LA++ A RVN V+PG + TP+ ++F +E +K ++ S
Sbjct: 191 LE--YTATKGAIVSFTRGLALQLAPKGIRVNGVAPGPVWTPLIPASFSEEAIK-QFGSET 247
Query: 241 PMGREGLPQELVGAYLYFA-SDASTYTTGSDLLVDGAYCV 279
PM R P E+ +Y++ A + S+Y TG L +G V
Sbjct: 248 PMKRAAQPVEVAPSYVFLACNHCSSYYTGQILHPNGGLIV 287
>At3g51680 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 303
Score = 92.8 bits (229), Expect = 5e-19
Identities = 79/265 (29%), Positives = 128/265 (47%), Gaps = 21/265 (7%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY-Q 86
L+GKVA++TG + GIG A A+ GA++ + N A A LS+ +VA+
Sbjct: 32 LEGKVAIITGGAHGIGKATVMLFARHGATVVIADVDNVAGSSLAKSLSSHKTSPMVAFIS 91
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
C V+ EA V+ + + +G++D+ NAGV + + D DE++ V+ +
Sbjct: 92 CDVSVEADVENLVNVTVARYGRLDILFNNAGVLGDQKKHKSILD--FDADEFDHVMRVNV 149
Query: 147 NGVYYCAKY-VGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
GV K+ A KR G ++ TAS++G + + Y A+K ++ K+ A E
Sbjct: 150 RGVGLGMKHGARAMIKRGFKGCIISTASVAGVMGGMG--PHAYTASKHAIVGLTKNAACE 207
Query: 206 WAGFA-RVNTVSPGYIATPI----------SNFVDEDLKNK---WHSLIPMGREGL-PQE 250
+ RVN +SP +AT + + D+D++ SL + E L +
Sbjct: 208 LGKYGIRVNCISPFGVATSMLVNAWRKTSGGDVEDDDVEEMEEFVRSLANLKGETLRAND 267
Query: 251 LVGAYLYFASDASTYTTGSDLLVDG 275
+ A LY ASD S Y G +L+VDG
Sbjct: 268 IAEAALYLASDESKYVNGHNLVVDG 292
>At1g54870 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 286
Score = 92.8 bits (229), Expect = 5e-19
Identities = 76/263 (28%), Positives = 131/263 (48%), Gaps = 20/263 (7%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWY------NSNAALVERAVELSAKYNV 80
S K +VA++TG SGIG AV A GA++A Y ++ E+ +
Sbjct: 32 SNKLRVALITGGDSGIGRAVGYCFASEGATVAFTYVKGQEEKDAQETLQMLKEVKTSDSK 91
Query: 81 KVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
+ +A + + K+ +++V+ FG+IDV I NA + + E D +
Sbjct: 92 EPIAIPTDLGFDENCKRVVDEVVNAFGRIDVLINNAAEQYESSTIEE-----IDEPRLER 146
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAK 200
V T+ ++ ++ + ++GS S++ T S++ + N L Y A K ++ F +
Sbjct: 147 VFRTNIFSYFFLTRH-ALKHMKEGS-SIINTTSVNAYKGNASLLD--YTATKGAIVAFTR 202
Query: 201 SLAVEWAGFA-RVNTVSPGYIATPI--SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLY 257
LA++ A RVN V+PG I TP+ ++F +E +KN + S +PM R G P E+ +Y++
Sbjct: 203 GLALQLAEKGIRVNGVAPGPIWTPLIPASFNEEKIKN-FGSEVPMKRAGQPIEVAPSYVF 261
Query: 258 FA-SDASTYTTGSDLLVDGAYCV 279
A + S+Y TG L +G V
Sbjct: 262 LACNHCSSYFTGQVLHPNGGAVV 284
>At4g03140 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 283
Score = 91.7 bits (226), Expect = 1e-18
Identities = 72/266 (27%), Positives = 125/266 (46%), Gaps = 31/266 (11%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAV--ELSAKYNVKVVAY 85
L+GKVA++TG +SGIG A A GA + + A ++ + E + +
Sbjct: 18 LEGKVALITGGASGIGKATAGKFISHGAKVII------ADIQPQIGRETEQELGPSCAYF 71
Query: 86 QCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTD 145
C VT+E+ + ++ + K+D+ NAG+P P + D + ++KVI+T+
Sbjct: 72 PCDVTKESDIANAVDFAVSLHTKLDIMYNNAGIPCKTPPSI----VDLDLNVFDKVINTN 127
Query: 146 FNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
GV K+ + SGS++ S++G + + Q Y+ +K+ VI +S A E
Sbjct: 128 VRGVMAGIKHAARVMIPRNSGSIICAGSVTGMMGGL--AQHTYSVSKSAVIGIVRSTASE 185
Query: 206 WAGF-ARVNTVSPGYIATPISNFVDEDLKNKWHSL-------------IPMGREGLPQEL 251
RVN +SP I T +FV ++++ + + + G P ++
Sbjct: 186 LCKHRIRVNCISPFAITT---SFVMDEMRQIYPGVDDSRLIQIVQSTGVLNGEVCEPTDV 242
Query: 252 VGAYLYFASDASTYTTGSDLLVDGAY 277
A +Y ASD S Y G +L+VDG +
Sbjct: 243 ANAAVYLASDDSKYVNGHNLVVDGGF 268
>At3g03980 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 270
Score = 91.3 bits (225), Expect = 1e-18
Identities = 77/265 (29%), Positives = 124/265 (46%), Gaps = 24/265 (9%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAV----------ELSAK 77
L G+VA+VTG+S GIG A+A LA+ GA + + Y S AA ER E++ K
Sbjct: 14 LAGRVAIVTGSSRGIGRAIAIHLAELGARIVINYTSKAADAERVASEINDFPVREEITGK 73
Query: 78 YNVKVVAYQCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDTD 136
+ + Q V+E ++VK + F + + + +AG+ K P + + T +
Sbjct: 74 -GPRAIVVQANVSEPSQVKSMFDAAESAFEAPVHILVNSAGILDPKYPTI----ADTSVE 128
Query: 137 EWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVI 196
+++ + G + C+K + K+ G G +++ S + P A Y A+KA V
Sbjct: 129 DFDHTFSVNTKGAFLCSKEAANRLKQGGGGRIILLTSSQTRSLK-PGFGA-YAASKAAVE 186
Query: 197 HFAKSLAVEWAGFA-RVNTVSPGYIATPISNFVD---EDLKNKWHSLIPMGREGLPQELV 252
K LA E G N V+PG IAT + F D +L K + P GR G +++V
Sbjct: 187 TMVKILAKELKGTGITANCVAPGPIATEM--FFDGKTPELVEKIAAESPFGRVGEAKDVV 244
Query: 253 GAYLYFASDASTYTTGSDLLVDGAY 277
+ A D + G + V+G Y
Sbjct: 245 PLVGFLAGDGGEWVNGQIIPVNGGY 269
>CE10908 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 313
Score = 88.6 bits (218), Expect = 9e-18
Identities = 78/271 (28%), Positives = 125/271 (45%), Gaps = 22/271 (8%)
Query: 16 PKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELS 75
P + S L SL GKVA+VTG +G+G A+A A GAS+A+ L + A E+
Sbjct: 12 PVVKSVALPPGSLNGKVALVTGGGTGLGKAIATTFAHLGASVAIAARRLDVLEKTADEIR 71
Query: 76 AKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKI-DVFIANAGVPWTKGPLVEAAESGTD 134
+ +Q V + AKV K + V ++ G D+ I NA G + A E
Sbjct: 72 SSTGGVCEPFQMDVKDPAKVAKAFDAVEKKLGHTPDILINNAA-----GNFIMATER-LS 125
Query: 135 TDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITA----SMSGHIVNIPQLQACYNA 190
+ + +I G + +G + +Q G+ V++ + SG +P
Sbjct: 126 PNAYGTIIDIVLKGTLHVTTELGRRCIQQKRGASVLSITTLYAQSGAPFVVPSA-----V 180
Query: 191 AKAGVIHFAKSLAVEWAGFA-RVNTVSPGYIAT--PISNFVDEDLKNKWHSL---IPMGR 244
+KAGV + KSLA EWA R N ++PG I T +LK+ ++ +P+GR
Sbjct: 181 SKAGVENMTKSLASEWAKHGLRFNAIAPGPIPTEGAFGRLFAGELKDSGDAMKASVPVGR 240
Query: 245 EGLPQELVGAYLYFASDASTYTTGSDLLVDG 275
G P+E+ + +SD ++ G+ + DG
Sbjct: 241 LGHPEEIANLAAFMSSDFMSWMNGAIIDFDG 271
>Hs7705907 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 270
Score = 88.2 bits (217), Expect = 1e-17
Identities = 76/254 (29%), Positives = 124/254 (47%), Gaps = 23/254 (9%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPV 89
GKV VVTG GIG + +GA + + + RA+E V ++ C V
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG--GRALEQELPGAVFIL---CDV 63
Query: 90 TEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGV 149
T+E VK + + I+ FG++D + NAG P + E T + +++ + G
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG----HHPPPQRPEE-TSAQGFRQLLELNLLGT 118
Query: 150 YYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQAC-YNAAKAGVIHFAKSLAVEWAG 208
Y K + + R+ G+++ +S+ G I Q QA Y A K V K+LA++ +
Sbjct: 119 YTLTK-LALPYLRKSQGNVINISSLVG---AIGQAQAVPYVATKGAVTAMTKALALDESP 174
Query: 209 F-ARVNTVSPGYIATPISNFVDEDLKNKWHSL------IPMGREGLPQELVGAYLYFASD 261
+ RVN +SPG I TP+ + + + S+ P+GR G P E+ A ++ AS+
Sbjct: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQPAEVGAAAVFLASE 234
Query: 262 ASTYTTGSDLLVDG 275
A+ + TG +LLV G
Sbjct: 235 AN-FCTGIELLVTG 247
>At3g46170 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 288
Score = 87.8 bits (216), Expect = 2e-17
Identities = 75/258 (29%), Positives = 120/258 (46%), Gaps = 20/258 (7%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYN------VK 81
LK KV +VTGASSGIG + L +AG + + A V+R L ++ N ++
Sbjct: 26 LKDKVVLVTGASSGIGREICLDLGKAGCKII----AVARRVDRLNSLCSEINSSSSTGIQ 81
Query: 82 VVAYQCPVTEEAK-VKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
A + VT +A ++K ++ FGKID I NAG+ +G + + + +EW+
Sbjct: 82 AAALKLDVTSDAATIQKVVQGAWGIFGKIDALINNAGI---RGNVKSSLD--LSKEEWDN 136
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAK 200
V T+ G + +KYV + G VI S I I Y +K GV +K
Sbjct: 137 VFKTNLTGPWLVSKYVCVLMRDAKLGGSVINISSIAGIRGILPGALAYACSKIGVDTMSK 196
Query: 201 SLAVEWAGF-ARVNTVSPGYIATPISN--FVDEDLKNKWHSLIPMG-REGLPQELVGAYL 256
+AVE RVN+++PG + I+ E KN +P+ ++ + +
Sbjct: 197 MMAVELGVHKIRVNSIAPGIFKSEITQGLMQKEWFKNVTERTVPLKLQQTVDPGITSLVR 256
Query: 257 YFASDASTYTTGSDLLVD 274
Y D+S Y +G+ +VD
Sbjct: 257 YLIHDSSQYISGNTYIVD 274
>At3g42960 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 272
Score = 87.8 bits (216), Expect = 2e-17
Identities = 78/264 (29%), Positives = 130/264 (48%), Gaps = 31/264 (11%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVT 90
KVA++TG + GIG A A + GA + V A ++E L A+ ++ C V+
Sbjct: 11 KVAIITGGARGIGAATARLFTENGAYVIV-----ADILENEGILVAE-SIGGCYVHCDVS 64
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVY 150
+EA V+ +E ++ G++DV NAG+ +G ++ G D D NK++ + NGV
Sbjct: 65 KEADVEAAVELAMRRKGRLDVMFNNAGMSLNEGSIM-----GMDVDMVNKLVSVNVNGVL 119
Query: 151 YCAKYVG-AQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAGF 209
+ K+ A K GS++ T+S SG + + Y +K + ++ A E
Sbjct: 120 HGIKHAAKAMIKGGRGGSIICTSSSSGLMGGLG--GHAYTLSKGAINGVVRTTACELGSH 177
Query: 210 A-RVNTVSPGYIATPI-----SNFVDEDLKN---------KWHSLIPMGREGLPQELVGA 254
RVN++SP + T I F++ D N + SL+ GR G +++ A
Sbjct: 178 GIRVNSISPHGVPTDILVNAYRKFLNHDKLNVAEVTDIIAEKGSLL-TGRAGTVEDVAQA 236
Query: 255 YLYFAS-DASTYTTGSDLLVDGAY 277
L+ AS ++S + TG +L+VDG Y
Sbjct: 237 ALFLASQESSGFITGHNLVVDGGY 260
>At2g47120 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 258
Score = 87.8 bits (216), Expect = 2e-17
Identities = 74/261 (28%), Positives = 126/261 (47%), Gaps = 21/261 (8%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L+GK+ ++TG +SGIG A GA + + + L + L K K Y+C
Sbjct: 6 LEGKIVIITGGASGIGADAARLFTDHGAKVVI-VDVQEELGQNVAVLIGKD--KASFYRC 62
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTD--EWNKVIHTD 145
VT E +V+ ++ +++ GK+DV +NAGV +E ES D D +++++ +
Sbjct: 63 DVTNETEVEDAVKFTVEKHGKLDVLFSNAGV-------LEPLESFLDFDLERFDRIMAVN 115
Query: 146 FNGVYYCAKYVGAQFKRQGS-GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
G K+ +G+ GS+V T S+S I Y A+K G++ +S
Sbjct: 116 VRGAAAFIKHAARAMVEKGTRGSIVCTTSVSAEIGG---GHHGYTASKHGLVGLIRSACG 172
Query: 205 EWAGFA-RVNTVSPGYIATPISN---FVDEDLKNKWHSL-IPMGREGLPQELVGAYLYFA 259
+ + RVN V+P +ATP+++ + L++ + + I G + L+ A
Sbjct: 173 DLGKYGIRVNGVAPYAVATPMTSHDEVTGKQLEDYFDAKGILKGMVLKASHVAQVALFLA 232
Query: 260 SDASTYTTGSDLLVDGAYCVL 280
SD S Y +G +L VDG Y V+
Sbjct: 233 SDDSAYISGQNLAVDGGYTVV 253
>At2g47140 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 264
Score = 86.7 bits (213), Expect = 3e-17
Identities = 76/269 (28%), Positives = 126/269 (46%), Gaps = 18/269 (6%)
Query: 20 SNVLDLFS-LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKY 78
SN L FS L GK+ ++TG +SGIG + GA + + + AV +
Sbjct: 4 SNDLFFFSRLDGKIVIITGGASGIGAESVRLFTEHGARVVIVDVQDELGQNVAVSIGED- 62
Query: 79 NVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEW 138
K Y C VT E +V+ ++ ++++GK+DV +NAGV P V + + +E
Sbjct: 63 --KASYYHCDVTNETEVENAVKFTVEKYGKLDVLFSNAGV---IEPFVSILD--LNLNEL 115
Query: 139 NKVIHTDFNGVYYCAKYVGAQFKRQG-SGSMVITASMSGHIVNIPQLQACYNAAKAGVIH 197
++ I + G K+ +G GS+V T S++ I Y +K G++
Sbjct: 116 DRTIAINLRGTAAFIKHAARAMVEKGIRGSIVCTTSVAAEIAG--TAPHGYTTSKHGLLG 173
Query: 198 FAKSLAVEWAGFA-RVNTVSPGYIATPI--SNFVDEDLKNKWHSLIPMGREGL---PQEL 251
KS + + RVN V+P +ATP+ + F E + ++ +G+ + +
Sbjct: 174 LIKSASGGLGKYGIRVNGVAPFGVATPLVCNGFKMEPNVVEQNTSASANLKGIVLKARHV 233
Query: 252 VGAYLYFASDASTYTTGSDLLVDGAYCVL 280
A L+ ASD S Y +G +L VDG Y V+
Sbjct: 234 AEAALFLASDESAYVSGQNLAVDGGYSVV 262
>Hs4503301 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 335
Score = 86.3 bits (212), Expect = 5e-17
Identities = 73/269 (27%), Positives = 115/269 (42%), Gaps = 33/269 (12%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
S +GKVA +TG +G+G + L+ GA + L A ++S++ KV A Q
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
C V + V+ T+ ++I+ G ++ I NA G + E + W +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAA-----GNFISPTER-LSPNAWKTITDIVL 169
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASM------SGHIVNIPQLQACYNAAKAGVIHFAK 200
NG + +G Q + G+ ++ + SG +V +AKAGV +K
Sbjct: 170 NGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSA-------SAKAGVEAMSK 222
Query: 201 SLAVEWAGFA-RVNTVSPGYIAT--------PISNFVDEDLKNKWHSLIPMGREGLPQEL 251
SLA EW + R N + PG I T P F E + IP GR G +EL
Sbjct: 223 SLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMI-----GRIPCGRLGTVEEL 277
Query: 252 VGAYLYFASDASTYTTGSDLLVDGAYCVL 280
+ SD +++ G+ + DG VL
Sbjct: 278 ANLAAFLCSDYASWINGAVIKFDGGEEVL 306
>CE21092 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 278
Score = 86.3 bits (212), Expect = 5e-17
Identities = 78/271 (28%), Positives = 116/271 (42%), Gaps = 43/271 (15%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL----SAKYNVKVVAYQ 86
KVA++TG+SSGIG + A LAQ GA + V S+ + E E+ + N+ +V
Sbjct: 7 KVAIITGSSSGIGRSTAVLLAQEGAKVTVTGRSSEKIQETVNEIHKNGGSSDNINIVLGD 66
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWT--KGPLVEAAESGTDTDEWNKVIHT 144
+ E + I+ + FGKID+ I NAG + G + A G D + +
Sbjct: 67 --LNESECQDELIKSTLSRFGKIDILINNAGAAFADPSGKIGSEAAIGIFDDMMKLNLRS 124
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQA---------CYNAAKAGV 195
V C ++ A G IVN+ + A Y KAG+
Sbjct: 125 VVELVKKCRPHLIAS---------------KGEIVNVSSIAAGPQPYIYYTYYGICKAGL 169
Query: 196 IHFAKSLAVEWAGF-ARVNTVSPGYIATPISNFV---------DEDLKNKWHSLIPMGRE 245
+SLA+E F RVN+VSPG I+T V E+ + IP GR
Sbjct: 170 DQLTRSLALELIPFDVRVNSVSPGLISTNFLGAVGMGDDVVKKTEEYYSTHRDCIPAGRT 229
Query: 246 GLPQELVGAYLYFAS-DASTYTTGSDLLVDG 275
G P+E+ + A +S Y G +++DG
Sbjct: 230 GKPEEIASLIAFLADRKSSAYIIGQSIVIDG 260
>At2g47130 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 257
Score = 86.3 bits (212), Expect = 5e-17
Identities = 73/264 (27%), Positives = 128/264 (47%), Gaps = 26/264 (9%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV-----KV 82
L GK+A++TG +SGIG GA + + V+ EL V K
Sbjct: 6 LDGKIAIITGGASGIGAEAVRLFTDHGAKVVI--------VDFQEELGQNVAVSVGKDKA 57
Query: 83 VAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVI 142
Y+C VT E +V+ ++ ++++GK+DV +NAGV G ++ + +++++ +
Sbjct: 58 SFYRCDVTNEKEVENAVKFTVEKYGKLDVLFSNAGVMEQPGSFLD-----LNLEQFDRTM 112
Query: 143 HTDFNGVYYCAKYVGAQFKRQGS-GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
+ G K+ +G+ GS+V T S++ I P A Y A+K ++ KS
Sbjct: 113 AVNVRGAAAFIKHAARAMVEKGTRGSIVCTTSVASEIGG-PGPHA-YTASKHALLGLVKS 170
Query: 202 LAVEWAGFA-RVNTVSPGYIATPISNFVDEDLKN-KWHSLIPMGREGL---PQELVGAYL 256
+ RVN V+P +AT I++ +E ++ + +S +G+ + + A L
Sbjct: 171 ACGGLGKYGIRVNGVAPYAVATAINSRDEETVRMVEEYSAATGILKGVVLKARHVAEAAL 230
Query: 257 YFASDASTYTTGSDLLVDGAYCVL 280
+ ASD S Y +G +L VDG Y V+
Sbjct: 231 FLASDDSAYVSGQNLAVDGGYSVV 254
>At3g04000 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 272
Score = 85.9 bits (211), Expect = 6e-17
Identities = 70/267 (26%), Positives = 129/267 (48%), Gaps = 22/267 (8%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERA-----------VELSA 76
L G+VA+VTG+S GIG A+A LA+ GA + V Y+++ E+ E++
Sbjct: 14 LAGRVAIVTGSSRGIGRAIAIHLAELGARVVVNYSTSPVEAEKVATAITTNCSKDAEVAG 73
Query: 77 KYNVKVVAYQCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESGTDT 135
K + +V+ + ++E ++VK ++ + F + + + +A + + S
Sbjct: 74 K-SPRVIVVKADISEPSQVKSLFDEAERVFESPVHILVNSAAIADPNHSTI----SDMSV 128
Query: 136 DEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGV 195
+ ++++I + G + CA+ + KR G G +++ ++ +N Y A+KA V
Sbjct: 129 ELFDRIISVNTRGAFICAREAANRLKRGGGGRIILLSTSLVQTLNTN--YGSYTASKAAV 186
Query: 196 IHFAKSLAVEWAGF-ARVNTVSPGYIATPI-SNFVDEDLKNKWHSLIPMGREGLPQELVG 253
AK LA E G VN VSPG +AT + + ++ K S GR G +++
Sbjct: 187 EAMAKILAKELKGTEITVNCVSPGPVATEMFYTGLSNEIVEKVKSQNLFGRIGETKDIAP 246
Query: 254 AYLYFASDASTYTTGSDLLVDGAYCVL 280
+ ASDA + G ++ +G C+L
Sbjct: 247 VVGFLASDAGEWINGQVIMANGG-CLL 272
>At3g29260 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 259
Score = 85.5 bits (210), Expect = 8e-17
Identities = 71/264 (26%), Positives = 125/264 (46%), Gaps = 26/264 (9%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV-----KV 82
L GK+ ++TG +SGIG A GA + + V+ EL V K
Sbjct: 6 LDGKIVIITGGASGIGAEAARLFTDHGAKVVI--------VDLQEELGQNVAVSIGLDKA 57
Query: 83 VAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVI 142
Y+C +T+E +V+ ++ +++ GK+DV +NAGV G +++ D + +++ +
Sbjct: 58 SFYRCDITDETEVENAVKFTVEKHGKLDVLFSNAGVMEPHGSILD-----LDLEAFDRTM 112
Query: 143 HTDFNGVYYCAKYVGAQFKRQGS-GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
+ G K+ G+ GS+V T S++ I P + Y A+K ++ +S
Sbjct: 113 AVNVRGAAAFIKHAARSMVASGTRGSIVCTTSVTAEIGG-PGPHS-YTASKHALLGLVRS 170
Query: 202 LAVEWAGFA-RVNTVSPGYIATPISNFVDEDLKNKWH----SLIPMGREGLPQELVGAYL 256
+ RVN V+P +AT ++++ +E +K + I G + + A L
Sbjct: 171 ACGGLGKYGIRVNGVAPYGVATGLTSYNEETVKMVEDYCSATAILKGVVLKARHVADAAL 230
Query: 257 YFASDASTYTTGSDLLVDGAYCVL 280
+ ASD S Y +G +L VDG Y V+
Sbjct: 231 FLASDDSVYISGQNLGVDGGYSVV 254
>CE02315 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 309
Score = 84.7 bits (208), Expect = 1e-16
Identities = 79/271 (29%), Positives = 122/271 (44%), Gaps = 22/271 (8%)
Query: 16 PKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELS 75
P S +L +LKGKVA+VTG +GIG A+A A GAS+A+ L + A E+
Sbjct: 11 PICNSPILRDGALKGKVALVTGGGTGIGKAIATTFAHLGASVAIAARRMEKLEQTAEEIM 70
Query: 76 AKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGK-IDVFIANAGVPWTKGPLVEAAESGTD 134
++ + + V T + + ++FGK D+ + NA G + A E
Sbjct: 71 KTTGGICEPFRMDIKDPGMVSDTFDKIDKKFGKHPDILVNNAA-----GNFIMATER-LS 124
Query: 135 TDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMV--ITA--SMSGHIVNIPQLQACYNA 190
+ +I G +G + + +G+ V ITA + SG +P
Sbjct: 125 PNAHGTIIDIVLKGTMNVTTELGKRCIQSKTGASVTSITAAYARSGAPFIVPSA-----V 179
Query: 191 AKAGVIHFAKSLAVEWAGFA-RVNTVSPGYIATP-----ISNFVDEDLKNKWHSLIPMGR 244
+KAGV KSLA EW+ + R N VSPG I T + + D+ K L P GR
Sbjct: 180 SKAGVEIMTKSLATEWSKYGLRFNAVSPGPIPTKGAWGRLFSGEMGDVAEKMKELNPEGR 239
Query: 245 EGLPQELVGAYLYFASDASTYTTGSDLLVDG 275
G P+E+ + +SD ++ G + +DG
Sbjct: 240 SGTPEEVANLVAFISSDHMSFMNGVIIDLDG 270
>Hs4504479 [IR] KOG4169 15-hydroxyprostaglandin dehydrogenase and related
dehydrogenases
Length = 266
Score = 84.3 bits (207), Expect = 2e-16
Identities = 60/212 (28%), Positives = 101/212 (47%), Gaps = 25/212 (11%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLA-VWYNSNAALVERAVELSAKYNVKVVAYQ 86
+ GKVA+VTGA+ GIG A AE L GA +A V +N A + +A K + Q
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 62
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTD- 145
C V ++ +++ T V+ FG++D+ + NAGV + W K + +
Sbjct: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------------NNEKNWEKTLQINL 108
Query: 146 ---FNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSL 202
+G Y Y+ Q G G ++I S ++ + Q Q Y A+K G++ F +S
Sbjct: 109 VSVISGTYLGLDYMSKQ--NGGEGGIIINMSSLAGLMPVAQ-QPVYCASKHGIVGFTRSA 165
Query: 203 AVE---WAGFARVNTVSPGYIATPISNFVDED 231
A+ R+N + PG++ T I ++++
Sbjct: 166 ALAANLMNSGVRLNAICPGFVNTAILESIEKE 197
>At5g50700 [Q] KOG1205 Predicted dehydrogenase
Length = 349
Score = 84.0 bits (206), Expect = 2e-16
Identities = 61/199 (30%), Positives = 102/199 (50%), Gaps = 8/199 (4%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
+L GKV ++TGASSGIG +A A GA LA+ L E A + VV
Sbjct: 44 NLYGKVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVH 103
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
V++ ++ ++D I FG++D + NAG+ T+ + E E T T V+ T+F
Sbjct: 104 ADVSKPDDCRRIVDDTITHFGRLDHLVNNAGM--TQISMFENIEDITRT---KAVLDTNF 158
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
G Y + + RQ +G ++ S S + P++ + YNA+KA ++ F +++ +E
Sbjct: 159 WGSVYTTR-AALPYLRQSNGK-IVAMSSSAAWLTAPRM-SFYNASKAALLSFFETMRIEL 215
Query: 207 AGFARVNTVSPGYIATPIS 225
G + V+PGYI + ++
Sbjct: 216 GGDVHITIVTPGYIESELT 234
>At5g50600 [Q] KOG1205 Predicted dehydrogenase
Length = 349
Score = 84.0 bits (206), Expect = 2e-16
Identities = 61/199 (30%), Positives = 102/199 (50%), Gaps = 8/199 (4%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
+L GKV ++TGASSGIG +A A GA LA+ L E A + VV
Sbjct: 44 NLYGKVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVH 103
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
V++ ++ ++D I FG++D + NAG+ T+ + E E T T V+ T+F
Sbjct: 104 ADVSKPDDCRRIVDDTITHFGRLDHLVNNAGM--TQISMFENIEDITRT---KAVLDTNF 158
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
G Y + + RQ +G ++ S S + P++ + YNA+KA ++ F +++ +E
Sbjct: 159 WGSVYTTR-AALPYLRQSNGK-IVAMSSSAAWLTAPRM-SFYNASKAALLSFFETMRIEL 215
Query: 207 AGFARVNTVSPGYIATPIS 225
G + V+PGYI + ++
Sbjct: 216 GGDVHITIVTPGYIESELT 234
>CE21095 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 280
Score = 83.2 bits (204), Expect = 4e-16
Identities = 80/265 (30%), Positives = 125/265 (46%), Gaps = 31/265 (11%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVE-RAVELSAKYNVKVV-AYQCP 88
K ++TG+S+GIG A AQ GA++ + S+ L E R + L + + K V +
Sbjct: 7 KTVIITGSSNGIGRTTAILFAQEGANVTITGRSSERLEETRQIILKSGVSEKQVNSVVAD 66
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAG--VPWTKGPLVEAAESGTD--TDEWNKVIHT 144
VT E + I +++FGKIDV + NAG +P G +GTD D ++K +
Sbjct: 67 VTTEDGQDQIINSTLKQFGKIDVLVNNAGAAIPDAFG------TTGTDQGIDIYHKTLKL 120
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQ---ACYNAAKAGVIHFAKS 201
+ V K V G +V +S IV PQ Q Y AKA + + +S
Sbjct: 121 NLQAVIEMTKKVKPHLV-ASKGEIVNVSS----IVAGPQAQPDFLYYAIAKAALDQYTRS 175
Query: 202 LAVEWAGFA-RVNTVSPGYIATPISNF--VDEDLKNKWHSL-------IPMGREGLPQEL 251
A++ A F RVN+VSPG + T +N + + K+++ IP+G G P+ +
Sbjct: 176 TAIDLAKFGIRVNSVSPGMVETGFTNAMGMPDQASQKFYNFMASHKECIPIGAAGKPEHI 235
Query: 252 VGAYLYFAS-DASTYTTGSDLLVDG 275
L+ A + S Y G ++ DG
Sbjct: 236 ANIILFLADRNLSFYILGQSIVADG 260
>7296704 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 264
Score = 82.8 bits (203), Expect = 5e-16
Identities = 84/264 (31%), Positives = 129/264 (48%), Gaps = 28/264 (10%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALV---ERAVELSAKYNVKVVAYQ 86
GKV ++TGA+SGIG A AE ++ GA LA+ L+ +R +++ +
Sbjct: 13 GKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEPYGIAGDLL 72
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
P E +KT E + GK+DV + AG+ T G L T+ + V+ +
Sbjct: 73 KPPEIECIARKTTE---RYEGKLDVLVNGAGIMPT-GTL-----QSTELACFTHVMEANV 123
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
+Y K + Q Q GS+V +S+ G + P L A YN +KA V F +SLA++
Sbjct: 124 RSGFYLTKLLLPQL-LQCKGSIVNVSSVCG-LRAFPNLVA-YNMSKAAVDQFTRSLALDL 180
Query: 207 A-GFARVNTVSPGYIATPI--SNFVDE-------DLKNKWHSLIPMGREGLPQELVGAYL 256
RVN V+PG I T + + +DE + K H+L GR G P+E+ A
Sbjct: 181 GPQGVRVNAVNPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHAL---GRIGEPKEVAAAIC 237
Query: 257 YFASDASTYTTGSDLLVDGAYCVL 280
+ AS+ +++ TG L VDG V+
Sbjct: 238 FLASELASFVTGVTLPVDGGKQVM 261
>7290108 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 270
Score = 81.6 bits (200), Expect = 1e-15
Identities = 71/212 (33%), Positives = 108/212 (50%), Gaps = 22/212 (10%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
SL KV +VTGASSGIG A+A+ LA+ GA+LA+ + A L L VVA
Sbjct: 2 SLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVA-- 59
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
VT++A ++ + +FG+IDV + NAG+ KG L++ D +E++ V++T+
Sbjct: 60 -DVTKDADA--IVQQTLAKFGRIDVLVNNAGI-LGKGGLID-----LDIEEFDAVLNTNL 110
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
GV K V + G++V +S +G L Y +KA + F K +A+E
Sbjct: 111 RGVILLTKAVLPHLLKT-KGAVVNVSSCAGIRPFAGALS--YGVSKAALDQFTKIVALEM 167
Query: 207 A-GFARVNTVSPGYIATPISNFVDEDLKNKWH 237
A RVN+V+PG+ D+ WH
Sbjct: 168 APQGVRVNSVNPGFRG-------DQHPSEHWH 192
>At5g50770 [Q] KOG1205 Predicted dehydrogenase
Length = 342
Score = 80.9 bits (198), Expect = 2e-15
Identities = 73/252 (28%), Positives = 122/252 (47%), Gaps = 20/252 (7%)
Query: 3 YTLATELPTPQEPPKLASNVLDLFS--LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVW 60
Y L PT Q S +LFS + GKV V+TGA+SGIG A+A + GA LA+
Sbjct: 18 YALLVFYPTYQRLKSAVSICRNLFSENVAGKVVVITGAASGIGEALAYEYGKRGAYLALV 77
Query: 61 YNSNAALVERAVELSAKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPW 120
L A + +V+ V++ ++ I + FG++D + NAGV
Sbjct: 78 DIRGEPLFHVAALAELYGSPEVLPLVADVSKLQDCERFIRATVLHFGRLDHLVTNAGV-- 135
Query: 121 TKGPLVEAAESGTDTDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVN 180
PL A+ D + + + +F G YC + + + ++ G +V+ AS G+I +
Sbjct: 136 --APLYFFADI-EDVSKASPAMDINFWGSVYCT-FFASPYLKKFRGRIVVIASGCGYIAS 191
Query: 181 IPQLQACYNAAKAGVIHFAKSLAVEWAGFARVNTVSPGYIATPISN----------FVDE 230
P+L + Y A+KA VI F ++L E+ V V+PG + + +S VD+
Sbjct: 192 -PRL-SFYCASKAAVIAFYETLRTEFGSDIGVTIVAPGIVDSEMSRGKFMTKDGKLVVDK 249
Query: 231 DLKNKWHSLIPM 242
+L++ S++P+
Sbjct: 250 ELRDVQMSVLPV 261
>At3g47350 [Q] KOG1205 Predicted dehydrogenase
Length = 308
Score = 80.9 bits (198), Expect = 2e-15
Identities = 64/200 (32%), Positives = 100/200 (50%), Gaps = 10/200 (5%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKY-NVKVVAY 85
++ GKV ++TGASSGIG VA A+ GA LA+ L E E S + + V+
Sbjct: 43 NVTGKVVLITGASSGIGEHVAYEYAKKGAKLALVARRKDRL-EIVAETSRQLGSGDVIII 101
Query: 86 QCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTD 145
V+ KK I++ I FGK+D I NAGVP T E T + N ++ +
Sbjct: 102 PGDVSNVEDCKKFIDETIHHFGKLDHLINNAGVPQT-----VIFEDFTQIQDANSIMDIN 156
Query: 146 FNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
F G Y Y R+ G +V+ +S + I Q + Y+A+KA ++ F ++L VE
Sbjct: 157 FWGSTYIT-YFAIPHLRKSKGKIVVISSATAIIP--LQAASVYSASKAALVKFFETLRVE 213
Query: 206 WAGFARVNTVSPGYIATPIS 225
+ ++ PG+I+T ++
Sbjct: 214 ISPDIKITIALPGFISTDMT 233
>At3g29250 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 260
Score = 80.9 bits (198), Expect = 2e-15
Identities = 69/260 (26%), Positives = 124/260 (47%), Gaps = 17/260 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L GK+A++TG +SGIG GA + + AV + K Y+C
Sbjct: 6 LDGKIAIITGGASGIGAEAVRLFTDHGAKVVIVDIQEELGQNLAVSIGLD---KASFYRC 62
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
VT+E V+ ++ +++ GK+DV +NAGV G +++ D + +++ + +
Sbjct: 63 NVTDETDVENAVKFTVEKHGKLDVLFSNAGVLEAFGSVLD-----LDLEAFDRTMAVNVR 117
Query: 148 GVYYCAKYVGAQFKRQGS-GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
G K+ G+ GS+V T S++ I P + Y A+K ++ +S
Sbjct: 118 GAAAFIKHAARSMVASGTRGSIVCTTSIAAEIGG-PGPHS-YTASKHALLGLIRSACAGL 175
Query: 207 AGFA-RVNTVSPGYIATPISNFVDED----LKNKWHSLIPM-GREGLPQELVGAYLYFAS 260
+ RVN V+P +AT +++ +E+ L+ +L + G + + A L+ AS
Sbjct: 176 GQYGIRVNGVAPYGVATGMTSAYNEEAVKMLEEYGEALGNLKGVVLKARHIAEAALFLAS 235
Query: 261 DASTYTTGSDLLVDGAYCVL 280
D S Y +G +L+VDG + V+
Sbjct: 236 DDSVYISGQNLVVDGGFSVV 255
>7296706_2 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 233
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/233 (29%), Positives = 117/233 (50%), Gaps = 16/233 (6%)
Query: 50 LAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKI 109
LA+ G L + + L E A + A + Q +T+EA+V++ + + + G+I
Sbjct: 2 LAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQADMTKEAEVQQIVGATLAKHGRI 61
Query: 110 DVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMV 169
DV + NAG+ L + T ++++++++T+ +Y + + G++V
Sbjct: 62 DVLVNNAGI------LETGSIEATSLEQFDRLMNTNVRSLYQLTMLATPELVKT-KGNIV 114
Query: 170 ITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA-GFARVNTVSPGYIATPI--SN 226
+S+ G + P + A YN +KA V F +A+E A RVN V+PG I T I
Sbjct: 115 NVSSVCG-LRAFPGVLA-YNVSKAAVDQFTACIALELAPKGVRVNAVNPGVIVTDIHKRG 172
Query: 227 FVDEDLKNKW--HSLI--PMGREGLPQELVGAYLYFASDASTYTTGSDLLVDG 275
+DE+ K+ H I +GR G +E+ A + ASD +++TTG L VDG
Sbjct: 173 GMDEETYAKFLEHCKITHALGRPGDVKEVAAAIAFLASDQASFTTGISLPVDG 225
>At4g13180 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 263
Score = 80.5 bits (197), Expect = 2e-15
Identities = 73/259 (28%), Positives = 122/259 (46%), Gaps = 15/259 (5%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAV-ELSAKYNVK-VVAY 85
L G+VA+VTGA+ G+G +A L GA + + Y S+++ E V EL+ +K +A
Sbjct: 13 LAGRVAIVTGATRGMGREIAIHLHSLGARVTINYVSSSSKAELLVSELNDSSQLKSAIAV 72
Query: 86 QCPVTEEAKVKKTIEDVIQEFG-KIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
+ V++ ++ + QEFG K+ + + AGV K P + S T ++++
Sbjct: 73 KADVSDPDQINNLFDQTEQEFGSKVHIVVNCAGVLDPKYPSL----SETTLEDFDNTFTI 128
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMV-ITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLA 203
+ G + C K + R G G ++ ++ SM G + Y A+KA V K LA
Sbjct: 129 NTRGSFLCCKEAAKRVMRGGGGRIIMMSTSMVG---GLAPGYGVYAASKAAVETMVKVLA 185
Query: 204 VEWAGF-ARVNTVSPGYIATPI--SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFAS 260
E G N V+PG +AT + + DE +K PMGR G +++ + A
Sbjct: 186 KELKGSRITANCVAPGPVATEMFYAGKSDETVK-MLAGACPMGRIGESKDITEIVGFLAG 244
Query: 261 DASTYTTGSDLLVDGAYCV 279
D + G + +G + V
Sbjct: 245 DGGEWINGQVIRANGGFVV 263
>YNL202w [R] KOG0725 Reductases with broad range of substrate specificities
Length = 295
Score = 80.1 bits (196), Expect = 3e-15
Identities = 76/258 (29%), Positives = 117/258 (44%), Gaps = 17/258 (6%)
Query: 24 DLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELS--AKYNVK 81
DLF KGKVA VTG + I E L G A+ + A +S AK
Sbjct: 23 DLF--KGKVAFVTGGAGTICRVQTEALVLLGCKAAIVGRDQERTEQAAKGISQLAKDKDA 80
Query: 82 VVAY-QCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNK 140
V+A V +V+ ++ +++FGKID IA A G V + + +
Sbjct: 81 VLAIANVDVRNFEQVENAVKKTVEKFGKIDFVIAGAA-----GNFV-CDFANLSPNAFKS 134
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAK 200
V+ D G + AK + K+ + ++A+ H +P Q AAKAG+ AK
Sbjct: 135 VVDIDLLGSFNTAKACLKELKKSKGSILFVSATF--HYYGVP-FQGHVGAAKAGIDALAK 191
Query: 201 SLAVEWAGFA-RVNTVSPGYIATP--ISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLY 257
+LAVE R N ++PG I + + K K + IP+ R G +++ + +Y
Sbjct: 192 NLAVELGPLGIRSNCIAPGAIDNTEGLKRLAGKKYKEKALAKIPLQRLGSTRDIAESTVY 251
Query: 258 FASDASTYTTGSDLLVDG 275
S A++Y TG+ L+VDG
Sbjct: 252 IFSPAASYVTGTVLVVDG 269
>CE03127 [Q] KOG1199 Short-chain alcohol dehydrogenase/3-hydroxyacyl-CoA
dehydrogenase
Length = 258
Score = 79.7 bits (195), Expect = 4e-15
Identities = 71/258 (27%), Positives = 119/258 (45%), Gaps = 14/258 (5%)
Query: 25 LFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVA 84
L S KG VA+VTG +SG+G AE LA+AGA +A+ + + A E+ +
Sbjct: 4 LRSTKGLVALVTGGASGLGKGAAEVLAKAGAQVAILDLPQSKGADVAKEIGGIFT----- 58
Query: 85 YQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
VT E +V+ V E+G++D + AG+ + + D ++ + I
Sbjct: 59 -PASVTSEEEVRAAFAKVQAEYGRLDALVNCAGIAYAFKLYSVQKKKHVDFEKIRQTIDV 117
Query: 145 D----FNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAK 200
+ FN + + +G K V+ + S + Q+ Y+A+K ++
Sbjct: 118 NVLGTFNVIRHGVALMGEHEKDANGQRGVVINTASVAAFDGQTGQSAYSASKGAIVGMTL 177
Query: 201 SLAVEWAGFA-RVNTVSPGYIATPISNFVDEDLKNKWHSLIP-MGREGLPQELVGAYLYF 258
LA ++AG R NT++PG + TP+ + + E +K+ LIP R G P E GA +
Sbjct: 178 PLARDFAGDGIRFNTIAPGLMDTPLLSSLPEKVKSFLAQLIPNPSRLGHPHE-YGALVQH 236
Query: 259 ASDASTYTTGSDLLVDGA 276
+ + Y G + DGA
Sbjct: 237 IIE-NQYLNGETIRFDGA 253
>Hs5031737 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 280
Score = 78.6 bits (192), Expect = 9e-15
Identities = 64/251 (25%), Positives = 116/251 (45%), Gaps = 12/251 (4%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L +VAVVTG++SGIG+A+A LA+ GA + + + V+RA+ + V C
Sbjct: 34 LANRVAVVTGSTSGIGFAIARRLARDGAHVVI-SSRKQQNVDRAMAKLQGEGLSVAGIVC 92
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V + ++ + ++ G +D + +AGV PLV + GT W+K++ +
Sbjct: 93 HVGKAEDREQLVAKALEHCGGVDFLVCSAGV----NPLV-GSTLGTSEQIWDKILSVNVK 147
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
+ + G++++ +S++ + N YN +K ++ ++LA+E A
Sbjct: 148 SPALLLSQL-LPYMENRRGAVILVSSIAAY--NPVVALGVYNVSKTALLGLTRTLALELA 204
Query: 208 -GFARVNTVSPGYIATPISNFV--DEDLKNKWHSLIPMGREGLPQELVGAYLYFASDAST 264
RVN V PG I T S +E L + + R G ++ G + S ++
Sbjct: 205 PKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDAS 264
Query: 265 YTTGSDLLVDG 275
Y G ++ V G
Sbjct: 265 YVNGENIAVAG 275
>CE02370 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 309
Score = 77.8 bits (190), Expect = 2e-14
Identities = 68/267 (25%), Positives = 120/267 (44%), Gaps = 14/267 (5%)
Query: 16 PKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELS 75
P S VL + KGK+ +VTG +GIG A+A A A++ + L + A +++
Sbjct: 11 PIRKSPVLRDGAFKGKLVLVTGGGTGIGKAIATTFAHLRATVVIAARRMEKLEQTARDIT 70
Query: 76 AKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKI-DVFIANAGVPWTKGPLVEAAESGTD 134
+Q + + V + + +FGK+ ++ + NA G + A E
Sbjct: 71 KITGGTCEPFQMDIKDPGMVSDAFDKIDMKFGKVPEILVNNAA-----GNFIMATEL-LS 124
Query: 135 TDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAG 194
++ + +I G + +G + + +G+ IT+ +G+ +KAG
Sbjct: 125 SNAYGTIIDIVLKGTFNVTTELGKRCIQNKTGAS-ITSITAGYARAGAPFIVPSAVSKAG 183
Query: 195 VIHFAKSLAVEWAGFA-RVNTVSPGYIATP-----ISNFVDEDLKNKWHSLIPMGREGLP 248
V KSLA EW+ + R N VSPG I T +++ D+ K L P GR G P
Sbjct: 184 VETMTKSLATEWSKYGLRFNAVSPGPIPTKGAWGRLNSGEMGDIAEKMKFLNPEGRVGSP 243
Query: 249 QELVGAYLYFASDASTYTTGSDLLVDG 275
+E+ + +SD ++ G+ + +DG
Sbjct: 244 EEVANLVAFISSDHMSFLNGAIIDLDG 270
>7293189 [I] KOG1206 Peroxisomal multifunctional beta-oxidation protein and
related enzymes
Length = 598
Score = 77.8 bits (190), Expect = 2e-14
Identities = 60/186 (32%), Positives = 92/186 (49%), Gaps = 19/186 (10%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAV----WYNSNAALVERAVELSA----KYNVK 81
G+VAVVTGA +G+G A A+ GA + V +S +RA ++ K +
Sbjct: 12 GRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGE 71
Query: 82 VVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKV 141
VA V + AKV IE I+ FG++D+ + NAG+ L + + T +WN V
Sbjct: 72 AVADYNSVIDGAKV---IETAIKAFGRVDILVNNAGI------LRDRSLVKTSEQDWNLV 122
Query: 142 IHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
G + C + K+Q G +++T+S SG N Q+ Y AAK G+I A +
Sbjct: 123 NDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVN--YTAAKMGLIGLANT 180
Query: 202 LAVEWA 207
+A+E A
Sbjct: 181 VAIEGA 186
>CE12594 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 277
Score = 76.6 bits (187), Expect = 4e-14
Identities = 76/265 (28%), Positives = 122/265 (45%), Gaps = 31/265 (11%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV---KVVAYQ 86
GK ++TG+SSGIG + A A+ GA + + S L E +++ K V K+ A
Sbjct: 6 GKSIIITGSSSGIGRSAAVIFAKEGAQVTITGRSADRLEETRLQI-LKAGVPAEKINAVV 64
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTD--TDEWNKVIHT 144
V E + + I + +FGKID+ + NAG T G S TD + + K
Sbjct: 65 ADVCEASGQDEVIRTTLAKFGKIDILVNNAGALLTDG------TSNTDQAVELYQKTFKL 118
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQAC---YNAAKAGVIHFAKS 201
+F V + ++ + G +V +S IV PQ Q Y AKA + + +
Sbjct: 119 NFQAVVEMTQKT-KEYLIKTKGEIVNVSS----IVAGPQAQPASPYYACAKAALDQYTRC 173
Query: 202 LAVEWAGF-ARVNTVSPGYIATPI--SNFVDEDLKNKWHSL-------IPMGREGLPQEL 251
A++ RVN+VSPG IAT + + E +K+++ IP+G G P+E+
Sbjct: 174 TAIDLIQHGVRVNSVSPGVIATGFLGAMGLPETASDKFYNFMGSQKECIPVGHCGKPEEI 233
Query: 252 VGAYLYFAS-DASTYTTGSDLLVDG 275
++ A S+Y G ++ DG
Sbjct: 234 ANIIVFLADRRLSSYIIGQSIVADG 258
>CE03951 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 277
Score = 76.6 bits (187), Expect = 4e-14
Identities = 72/271 (26%), Positives = 115/271 (41%), Gaps = 40/271 (14%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAAL--VERAVELSAKYNVKVVAYQC 87
GKVA++TG+S GIG A A A+ GA + V S L ++A+ + + +
Sbjct: 7 GKVAIITGSSFGIGRATALLFAKEGAKVTVTGRSEERLQGSKQALLDAGISDSNFLIVPA 66
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
+T + I +++FG+I++ + NAG + G DT + KV+ +
Sbjct: 67 DITTSSGQDALISKTLEKFGQINILVNNAGASIADSQNRAGLDQGIDT--YEKVLKLNVQ 124
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQAC---------YNAAKAGVIHF 198
V + + A G IVN+ + A Y AKA + +
Sbjct: 125 SVIEMTQKIRPHL-----------AKTRGEIVNVSSVAALKFAHVRNPYYPLAKAALDQY 173
Query: 199 AKSLAVEWAGFA-RVNTVSPGYIATPI------------SNFVDEDLKNKWHSLIPMGRE 245
+S A++ RVNTV+PG +AT F D+ NK S IP G
Sbjct: 174 TRSAAIDLISQGIRVNTVNPGVVATGFHESCTGLSTEESQKFYDKVGANK--SAIPCGFS 231
Query: 246 GLPQELVGAYLYFAS-DASTYTTGSDLLVDG 275
G P+ + A + A D+S Y G +++ DG
Sbjct: 232 GRPEHIAKAIAFLADRDSSEYIIGQNIIADG 262
>CE14538 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 280
Score = 75.9 bits (185), Expect = 6e-14
Identities = 78/272 (28%), Positives = 120/272 (43%), Gaps = 44/272 (16%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV---KVVAYQC 87
+VA+VTG+S+GIG A A LA GA + + NA +E + + K V + +
Sbjct: 8 EVAIVTGSSNGIGRATAILLASEGAKVTI-TGRNAERLEESRQALLKVGVPSGHINSVVA 66
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
VT A I+ +++FGKI++ I NAG L+ E T+T
Sbjct: 67 DVTTGAGQDVLIDSTLKKFGKINILINNAGA------LIVDPEGKTNTS----------T 110
Query: 148 GVYYCAKYVGAQFKRQGSGSMVI---TASMSGHIVNIPQLQA---------CYNAAKAGV 195
GV C K F+ + I A+ G IVN+ + A Y+AAKA +
Sbjct: 111 GVETCLKTFQLNFQSVVEMTQKIRPHLANTHGEIVNVSSVGAGPAAENRFPYYSAAKAAL 170
Query: 196 IHFAKSLAVEW-AGFARVNTVSPGYIA---TPISNFVDEDLKNKWH-------SLIPMGR 244
++++ A++ RVN V PG++A T ++ + D K + S IP G
Sbjct: 171 DQYSRNTAIDLIPDGIRVNIVQPGFVATGFTTAASGMSPDASAKMYEGIGANTSCIPAGY 230
Query: 245 EGLPQELVGAYLYFAS-DASTYTTGSDLLVDG 275
G P+ L + A AS Y G ++ DG
Sbjct: 231 CGRPEHLASVIAFLADRKASEYIVGQTIIADG 262
>Hs4758504 [Q] KOG1199 Short-chain alcohol dehydrogenase/3-hydroxyacyl-CoA
dehydrogenase
Length = 261
Score = 75.5 bits (184), Expect = 8e-14
Identities = 73/259 (28%), Positives = 121/259 (46%), Gaps = 18/259 (6%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
S+KG VAV+TG +SG+G A AE L GAS + N+ +A +L V
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN----NCVFAP 62
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDT-DEWNKVIHTD 145
VT E V+ + +FG++DV + AG+ + T T +++ +V+ +
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIA-VASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 146 FNGVYYCAKYVGAQFKR----QGS--GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
G + + V + + QG G ++ TAS++ + QA Y+A+K G++
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVG--QAAYSASKGGIVGMT 179
Query: 200 KSLAVEWAGFA-RVNTVSPGYIATPISNFVDEDLKNKWHSLIPM-GREGLPQELVGAYLY 257
+A + A RV T++PG TP+ + E + N S +P R G P E A+L
Sbjct: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEY--AHLV 237
Query: 258 FASDASTYTTGSDLLVDGA 276
A + + G + +DGA
Sbjct: 238 QAIIENPFLNGEVIRLDGA 256
>Hs10190704 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 292
Score = 75.1 bits (183), Expect = 1e-13
Identities = 70/259 (27%), Positives = 116/259 (44%), Gaps = 26/259 (10%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L+ KVA +TG SGIG+ +AE + G + S ++ A +L+ + +
Sbjct: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V V ++ ++EFG+ID+ I A + + + V+ D +
Sbjct: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFL------CPAGALSFNAFKTVMDIDTS 139
Query: 148 GVYYCAKYVGAQFKRQGSGSMV-ITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
G + ++ + +F R G +V ITA++ LQ +AKA V + LAVEW
Sbjct: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGN---RGQALQVHAGSAKAAVDAMTRHLAVEW 196
Query: 207 A-GFARVNTVSPGYIATPISNFVDEDLK---------NKWHSLIPMGREGLPQELVGAYL 256
RVN+++PG PIS E L+ + + P+ R G E+ + L
Sbjct: 197 GPQNIRVNSLAPG----PISG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVL 250
Query: 257 YFASDASTYTTGSDLLVDG 275
Y AS ++Y TG+ L+ DG
Sbjct: 251 YLASPLASYVTGAVLVADG 269
>Hs10047132 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 245
Score = 75.1 bits (183), Expect = 1e-13
Identities = 67/257 (26%), Positives = 114/257 (44%), Gaps = 24/257 (9%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L GKV ++T A+ GIG A A A+ GA + + + L E K Q
Sbjct: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE---------KYPGIQT 54
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V + K KK I+ E ++DV AG G +++ E +W+ ++ +
Sbjct: 55 RVLDVTK-KKQIDQFANEVERLDVLFNVAGFVH-HGTVLDCEEK-----DWDFSMNLNVR 107
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
+Y K + Q SG+++ +S++ + + + Y+ KA VI KS+A ++
Sbjct: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVN-RCVYSTTKAAVIGLTKSVAADFI 166
Query: 208 GFA-RVNTVSPGYIATPI------SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFAS 260
R N V PG + TP + E+ +N + GR +E+ +Y AS
Sbjct: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226
Query: 261 DASTYTTGSDLLVDGAY 277
D S Y TG+ +++DG +
Sbjct: 227 DESAYVTGNPVIIDGGW 243
>CE05526 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 278
Score = 75.1 bits (183), Expect = 1e-13
Identities = 68/264 (25%), Positives = 121/264 (45%), Gaps = 29/264 (10%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSA----KYNVKVVAYQ 86
KVA++TG+S+GIG A A A+ GA + + L E ++ A + NV V
Sbjct: 7 KVAIITGSSNGIGRATAVLFAREGAKVTITGRHAERLEETRQQILAAGVSEQNVNSVV-- 64
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDT----DEWNKVI 142
VT +A + + + +FGK+D+ + NAG + ++S T T + ++ +
Sbjct: 65 ADVTTDAGQDEILSTTLGKFGKLDILVNNAGA------AIPDSQSKTGTAQSIESYDATL 118
Query: 143 HTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSL 202
+ + V K G +V +S++ + P Y+ AKA + + ++
Sbjct: 119 NLNLRSVIALTKKAVPHLS-STKGEIVNISSIASGLHATPDF-PYYSIAKAAIDQYTRNT 176
Query: 203 AVEWAGFA-RVNTVSPGYIATPISNF--VDEDLKNKWHS-------LIPMGREGLPQELV 252
A++ RVN++SPG +AT + + E+ K++S +P G G PQ++
Sbjct: 177 AIDLIQHGIRVNSISPGLVATGFGSAMGMPEETSKKFYSTMATMKECVPAGVMGQPQDIA 236
Query: 253 GAYLYFAS-DASTYTTGSDLLVDG 275
+ A S+Y G L+VDG
Sbjct: 237 EVIAFLADRKTSSYIIGHQLVVDG 260
>7294452 [Q] KOG1205 Predicted dehydrogenase
Length = 266
Score = 75.1 bits (183), Expect = 1e-13
Identities = 64/202 (31%), Positives = 100/202 (48%), Gaps = 13/202 (6%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVT 90
KVAVV+GAS+GIG A L AG + + + + LS + ++ A +C +T
Sbjct: 21 KVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDIT 80
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVY 150
+E +V K + ++ G +DV ++NAG+ T G L E D I T+ G
Sbjct: 81 QEDQVLKAFDWTCRQLGGVDVLVSNAGIIGT-GELSER----DDGPAMRSTIETNIMGTV 135
Query: 151 YCAKYVGAQFKRQGS-GSMVITASMSGH-IVNI-PQLQA--CYNAAKAGVIHFAKSLAVE 205
YC + KR+G+ G +VI S++G+ + N+ PQL + Y A K + + E
Sbjct: 136 YCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQE 195
Query: 206 WAGF---ARVNTVSPGYIATPI 224
+ RV+TVSPG + T I
Sbjct: 196 FQRHKTAVRVSTVSPGIVDTVI 217
>Hs14754051 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 245
Score = 74.7 bits (182), Expect = 1e-13
Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 24/257 (9%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L GKV ++T A+ GIG A A + GA + + V + EL K + Q
Sbjct: 4 LDGKVIILTAAAQGIGQAAALAFVREGAKVI----ATDINVSKLQELE-----KYLGIQT 54
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V + K KK I+ E ++DV AG G +++ E +W+ ++ +
Sbjct: 55 RVLDVTK-KKQIDQFANEVERLDVLFNVAGFVH-HGTVLDCEEK-----DWDFSMNLNVR 107
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
Y K + Q SG+++ S+ I + + Y+ KA VI KS+A ++
Sbjct: 108 STYLMIKAFLPKMLAQKSGNIITMFSVVSSIKGVVN-RCVYSTTKAAVIGLTKSVAADFI 166
Query: 208 GFA-RVNTVSPGYIATPI------SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFAS 260
R N V PG + TP + E+ +N + MGR +E+ +Y AS
Sbjct: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKMGRFATAEEIAMLCVYVAS 226
Query: 261 DASTYTTGSDLLVDGAY 277
D S Y TG+ +++DG +
Sbjct: 227 DESAYVTGNPVIIDGGW 243
>SPAC4H3.08 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 286
Score = 74.3 bits (181), Expect = 2e-13
Identities = 62/253 (24%), Positives = 106/253 (41%), Gaps = 17/253 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWY----NSNAALVERAVELSAKYNVKVV 83
L K ++TG SGIG A A A+ G+ L + +A + +E +
Sbjct: 40 LAEKKTLLTGGDSGIGKAAAVMFAREGSDLVISCLPEERDDAEVTRDLIEREGR---NCW 96
Query: 84 AYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
++ + + + ++ +++ G IDV + N V + D ++W+
Sbjct: 97 IWEGKLDKSDNCRDLVDFALKKLGWIDVLVNNIAYQQ-----VAQSIEDIDDEQWDLTFK 151
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLA 203
T+ ++ K A SGS ++ S V P L Y + K + F + L+
Sbjct: 152 TNIFSFFWVTK---AAISHMKSGSSIVNCSSINAYVGRPDLLD-YTSTKGAITAFTRGLS 207
Query: 204 VEWAGFA-RVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDA 262
++A RVN V+PG I TP+ + K + +P+GR G P E+ YL+ A
Sbjct: 208 NQYAQHGIRVNAVAPGPIYTPLVSSTFPKEKIELSDQVPLGRMGQPVEVASCYLFLACSD 267
Query: 263 STYTTGSDLLVDG 275
Y TG L +G
Sbjct: 268 GGYMTGQTLHPNG 280
>CE05752 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 284
Score = 74.3 bits (181), Expect = 2e-13
Identities = 73/273 (26%), Positives = 122/273 (43%), Gaps = 46/273 (16%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV---KVVAYQC 87
KVA++TG+S+GIG A A LA GA + V NA +E + V V+
Sbjct: 7 KVAIITGSSNGIGQATARLLASEGAKVTV-TGRNAERLEETKNILLGAGVPEGNVLVVVG 65
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFI--ANAGVPWTKGPLVEAAESGTD--TDEWNKVIH 143
+T+E+ + I+ + +FGKID+ + A AG+P +G +SG + D ++K
Sbjct: 66 DITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQG------KSGVNQSIDTYHKTFE 119
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQA---------CYNAAKAG 194
+ V + A G IVNI + A Y+ AKA
Sbjct: 120 LNVQSVIEMTQKARPHL-----------AKTQGEIVNISSIGAGPAAQVASPYYSIAKAA 168
Query: 195 VIHFAKSLAVEWAGFA-RVNTVSPGYIAT---PISNFVDEDLKNKWHSLIPMGREGLPQ- 249
+ + ++ A++ RVN+VSPG ++T +S + E+ ++ + RE +P+
Sbjct: 169 LDQYTRTAAIDLVPEGIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYLGAQRECIPRG 228
Query: 250 -----ELVGAYLYFASD--ASTYTTGSDLLVDG 275
E + + F +D AS Y G ++ DG
Sbjct: 229 FCAVPEDIAKVIAFLADRNASNYIIGQTIVADG 261
>7292613 [Q] KOG1205 Predicted dehydrogenase
Length = 250
Score = 74.3 bits (181), Expect = 2e-13
Identities = 62/205 (30%), Positives = 98/205 (47%), Gaps = 15/205 (7%)
Query: 29 KGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCP 88
+ +VAVVTGASSGIG A+A+ L AG ++ + E EL A+ K+ A C
Sbjct: 5 QNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQRELPAEKRGKLFALYCD 64
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNG 148
V E+ V + + +IQ+ G IDV + NAG G LV+ + +V+ T+ G
Sbjct: 65 VGNESSVNEAFDWIIQKLGAIDVLVNNAGT-LQPGYLVD-----MNPAVMQQVLQTNIMG 118
Query: 149 VYYCA-KYVGAQFKRQGSGSMVITASMSGH-----IVNIPQLQACYNAAKAGVIHFAKSL 202
+ C + V + +R+ G +V+ S+ GH + Y +K V A+
Sbjct: 119 IVLCTQRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGY 178
Query: 203 AVEWAGFA---RVNTVSPGYIATPI 224
E+ G ++ +VSPG + T I
Sbjct: 179 RQEFFGLGTRIKITSVSPGVVDTEI 203
>Hs20149619 [Q] KOG1205 Predicted dehydrogenase
Length = 325
Score = 73.9 bits (180), Expect = 2e-13
Identities = 57/204 (27%), Positives = 101/204 (48%), Gaps = 14/204 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ- 86
L+ V V+TGA+SG+G A+ AGA L + + AL E EL+A + KV ++
Sbjct: 50 LRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKP 109
Query: 87 ----CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVI 142
+T+ + +++Q FG +D+ + NAG+ + +G +++ T D +V+
Sbjct: 110 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISY-RGTIMD-----TTVDVDKRVM 163
Query: 143 HTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSL 202
T++ G K + ++ G +V +S+ G ++IP ++ Y A+K F L
Sbjct: 164 ETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK-MSIP-FRSAYAASKHATQAFFDCL 221
Query: 203 AVEWAGF-ARVNTVSPGYIATPIS 225
E + V +SPGYI T +S
Sbjct: 222 RAEMEQYEIEVTVISPGYIHTNLS 245
>CE23899 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 279
Score = 73.9 bits (180), Expect = 2e-13
Identities = 68/264 (25%), Positives = 117/264 (43%), Gaps = 27/264 (10%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL--SAKYNVKVVAYQC 87
GKVA+VTG+S+GIG A A LAQ GA + + + L E E+ S V++
Sbjct: 6 GKVALVTGSSNGIGRATAVLLAQEGAKVTITGRNADRLEETRQEILKSGVPEDHVLSIAT 65
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTD--EWNKVIHTD 145
+ E + + IQ+FG++D+ + NAG + + G D D +++++ +
Sbjct: 66 DLATEKGQDELVNSTIQKFGRLDILVNNAGAAFND----DQGRVGVDQDVSVYDRIMQIN 121
Query: 146 FNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQAC---YNAAKAGVIHFAKSL 202
V + + G +V +S+ PQ Q Y +KA + + +S
Sbjct: 122 MRSVVTLTQKAKEHLVK-AKGEVVNVSSIGAG----PQAQPTFMYYAMSKAALDQYTRSA 176
Query: 203 AVEWAGF-ARVNTVSPGYIATPISNF--VDEDLKNKW-------HSLIPMGREGLPQELV 252
A++ + RVN+VSPG + T + D+ K+ IP G+ G P ++
Sbjct: 177 AIDLIQYGVRVNSVSPGAVVTGFGEAMGMPADMHEKYGHFMESRKECIPCGKMGQPIDIA 236
Query: 253 GAYLYFAS-DASTYTTGSDLLVDG 275
+ A S+Y G ++ DG
Sbjct: 237 NIIAFLADRKLSSYIIGQSIVADG 260
>At3g47360 [Q] KOG1205 Predicted dehydrogenase
Length = 309
Score = 73.9 bits (180), Expect = 2e-13
Identities = 64/197 (32%), Positives = 96/197 (48%), Gaps = 12/197 (6%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKY-NVKVVAYQCPV 89
KV ++TGASSGIG VA A+ GA LA+ L E E S + + V+ V
Sbjct: 48 KVVLITGASSGIGEHVAYEYAKKGAYLALVARRRDRL-EIVAETSRQLGSGNVIIIPGDV 106
Query: 90 TEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGV 149
+ KK I++ I+ FGK+D I NAGV T E T + N ++ +F G
Sbjct: 107 SNVEDCKKFIDETIRHFGKLDHLINNAGVFQT-----VLFEDFTQIQDANPIMDINFWGT 161
Query: 150 YYCAKYVGAQFKRQGSGSMVITASMSGHIVNIP-QLQACYNAAKAGVIHFAKSLAVEWAG 208
Y Y R+ G +V S S NIP L + Y A+KA ++ F ++L +E +
Sbjct: 162 TYIT-YFAIPHLRKSKGKIVAITSGS---ANIPLPLASIYAASKAALLRFFETLRIELSP 217
Query: 209 FARVNTVSPGYIATPIS 225
++ V PG ++T ++
Sbjct: 218 DIKITIVLPGVVSTDMT 234
>YKR009c [I] KOG1206 Peroxisomal multifunctional beta-oxidation protein and
related enzymes
Length = 900
Score = 73.6 bits (179), Expect = 3e-13
Identities = 64/202 (31%), Positives = 96/202 (46%), Gaps = 23/202 (11%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAV----------WYNSNAALVERAVELSA 76
S K +V V+TGA G+G A A GA + V +NS AA + V+
Sbjct: 6 SFKDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGTLGGSGHNSKAA--DLVVDEIK 63
Query: 77 KYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTD 136
K VA V E + K IE I+EFG++DV I NAG+ L + + +
Sbjct: 64 KAGGIAVANYDSVNENGE--KIIETAIKEFGRVDVLINNAGI------LRDVSFAKMTER 115
Query: 137 EWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVI 196
E+ V+ G Y ++ + Q G ++ TAS +G N QA Y+AAK G++
Sbjct: 116 EFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNFG--QANYSAAKMGLV 173
Query: 197 HFAKSLAVEWAGF-ARVNTVSP 217
A++LA E A + VN+++P
Sbjct: 174 GLAETLAKEGAKYNINVNSIAP 195
Score = 65.9 bits (159), Expect = 6e-11
Identities = 64/222 (28%), Positives = 100/222 (44%), Gaps = 14/222 (6%)
Query: 15 PPKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL 74
PP +V + SL KV VVTGA G+G + A A+ GA + V + V +
Sbjct: 308 PPNEQGSV-KIKSLCNKVVVVTGAGGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEINK 366
Query: 75 SAKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTD 134
+ VTE + I+ I +F ++D+ + NAG+ K L E
Sbjct: 367 LYGEGTAIPDSHDVVTEAPLI---IQTAISKFQRVDILVNNAGILRDKSFLKMKDE---- 419
Query: 135 TDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAG 194
EW V+ + +K V F +Q SG ++ T S SG N QA Y AAKA
Sbjct: 420 --EWFAVLKVHLFSTFSLSKAVWPIFTKQKSGFIINTTSTSGIYGNFG--QANYAAAKAA 475
Query: 195 VIHFAKSLAVEWAGFARVNTVSPGYIATPISN--FVDEDLKN 234
++ F+K++A+E A + V + T ++ F +++L N
Sbjct: 476 ILGFSKTIALEGAKRGIIVNVIAPHAETAMTKTIFSEKELSN 517
>CE05726 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 277
Score = 73.2 bits (178), Expect = 4e-13
Identities = 70/269 (26%), Positives = 117/269 (43%), Gaps = 39/269 (14%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV---KVVAYQ 86
GK ++TG+S+GIG + A A+ GA + + + L E ++ K V K+ A
Sbjct: 6 GKSVIITGSSNGIGRSAAVIFAKEGAQVTITGRNEDRLEETKQQI-LKAGVPAEKINAVV 64
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
VTE + I + +FGKID+ + NAG G A + + + K +F
Sbjct: 65 ADVTEASGQDDIINTTLAKFGKIDILVNNAGANLADG----TANTDQPVELYQKTFKLNF 120
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQA---------CYNAAKAGVIH 197
V + ++ ++ T G IVN+ + A Y AKA +
Sbjct: 121 QAV--------IEMTQKTKEHLIKT---KGEIVNVSSIVAGPQAHSGYPYYACAKAALDQ 169
Query: 198 FAKSLAVEWAGF-ARVNTVSPGYIATPISNF--VDEDLKNKWHSL-------IPMGREGL 247
+ + A++ RVN+VSPG +AT + E +K +S IP+G G
Sbjct: 170 YTRCTAIDLIQHGVRVNSVSPGAVATGFMGAMGLPETASDKLYSFIGSRKECIPVGHCGK 229
Query: 248 PQELVGAYLYFAS-DASTYTTGSDLLVDG 275
P+E+ ++ A + S+Y G ++ DG
Sbjct: 230 PEEIANIIVFLADRNLSSYIIGQSIVADG 258
>7295621 [Q] KOG1205 Predicted dehydrogenase
Length = 247
Score = 73.2 bits (178), Expect = 4e-13
Identities = 65/242 (26%), Positives = 103/242 (41%), Gaps = 34/242 (14%)
Query: 32 VAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVTE 91
VAVVTGASSGIG A+ L AG + L + EL ++ QC V++
Sbjct: 8 VAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDVSD 67
Query: 92 EAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVYY 151
+ V + V + G +D+ I NAG + G L+ + D +++ T+ GV Y
Sbjct: 68 VSSVNAVFDAVQGDLGNVDILINNAG-KLSGGQLLTMS-----VDTVQQMLQTNVMGVVY 121
Query: 152 CAKYVGAQFK-RQGSGSMVITASMSGHIVNIP-----QLQACYNAAKAGVIHFAKSLAVE 205
C + + RQ G +V+ S+ GH + P Q Y A K + + E
Sbjct: 122 CTQRAFESMRQRQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQE 181
Query: 206 WAGF---ARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLP----QELVGAYLYF 258
F +V ++SPG + T L+P+ +GLP +++ A +Y
Sbjct: 182 MRDFKTKVKVTSISPGLVDT---------------ELVPLDYKGLPMLQAEDVANAIMYV 226
Query: 259 AS 260
S
Sbjct: 227 LS 228
>CE12990 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 279
Score = 72.4 bits (176), Expect = 7e-13
Identities = 76/268 (28%), Positives = 121/268 (44%), Gaps = 37/268 (13%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVE-------RAVELSAKYNVKV 82
GK ++TG+SSGIG A A A+ GA + + NA +E + V+ NV V
Sbjct: 6 GKSVIITGSSSGIGRATAVLFAKNGAQVTI-TGRNAEKLEATKKKLLKVVKTPDSVNVVV 64
Query: 83 VAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVI 142
+T+ + I+ +++FGKID+ I NAG G + D ++K
Sbjct: 65 ----ANLTDAQGQDQIIQSAVKKFGKIDILINNAGANVVDG----TVNTDQSIDLYHKTF 116
Query: 143 HTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSL 202
+F V K ++ + G +V +S++ + + Y AAKA + + + +
Sbjct: 117 QINFQAVVEMVKKT-KKYLIESKGEIVNVSSIAAGPQAV-SMSPYYAAAKAALNQYTRCV 174
Query: 203 AVEW-AGFARVNTVSPGYIATPISNF-----VDEDLKNKWHSL-------IPMGREGLPQ 249
A++ RVN+VSPG IAT NF V E + K +L IP G G P+
Sbjct: 175 ALDLIKQGVRVNSVSPGIIAT---NFMGAMGVPEQAQKKIVNLFASEKGCIPAGVPGKPE 231
Query: 250 ELVGAYLYFASD--ASTYTTGSDLLVDG 275
+ + + F SD S Y G ++ DG
Sbjct: 232 D-IAELIVFLSDRKRSFYIVGQSIVADG 258
>7290988 [Q] KOG1205 Predicted dehydrogenase
Length = 249
Score = 72.4 bits (176), Expect = 7e-13
Identities = 60/220 (27%), Positives = 100/220 (45%), Gaps = 17/220 (7%)
Query: 29 KGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCP 88
+ +VAV++GASSGIG A A L AG + L + L A+ ++ ++C
Sbjct: 5 QNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFHQHKCD 64
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNG 148
V++E +V E + +E G IDV I NAG+ G L++ T + N ++ T+ G
Sbjct: 65 VSQELQVDTAFEWIEKELGGIDVLINNAGIV-LGGQLID-----MPTKDINNILQTNLMG 118
Query: 149 VYYCAKYVGAQF-KRQGSGSMVITASMSGHIVNIPQ-LQACYNA------AKAGVIHFAK 200
YC K + +RQ +G ++ S +G P NA A V +
Sbjct: 119 SIYCTKLAASSMRRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICR 178
Query: 201 SLAVEWAGFARVNTVSPGYIATPISNFVDEDLKNKWHSLI 240
+ + +++PG++AT I V ++ K K +I
Sbjct: 179 QELINQGSKIKTTSINPGWVATEI---VPDETKAKLGEVI 215
>SPBC30D10.05c [Q] KOG1204 Predicted dehydrogenase
Length = 247
Score = 72.0 bits (175), Expect = 9e-13
Identities = 72/247 (29%), Positives = 110/247 (44%), Gaps = 24/247 (9%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVT 90
KV ++TG+S GIG A AE L + +AV + +L L + V + VT
Sbjct: 7 KVILLTGSSKGIGLATAEALQKKAKVIAV----SRSLTPELETLLIQNPDSFVHVKGDVT 62
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVY 150
E K +IE I++FGK+D I NAGV P+ + A++ D +EW K+ +F V
Sbjct: 63 EVGKA--SIETAIKKFGKLDSVILNAGV---LEPIAKIADA--DINEWRKLFDINFFSVV 115
Query: 151 YCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAGFA 210
KY R+ G++VI + SG V + A Y +KA + +L E
Sbjct: 116 ETVKY-AIPHLRKTKGTIVIVS--SGAAVRVFPAWAAYCCSKAAINMLVMNLGSEEPDIM 172
Query: 211 RVNTVSPGYIATPI---------SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASD 261
V V PG + TP+ + D N + L G+ PQ++ A + A +
Sbjct: 173 SV-AVRPGVVDTPMQVSIRNDSNKEAMGGDTHNFFKELKTSGQLVAPQDIAKALSFLALN 231
Query: 262 ASTYTTG 268
+ TG
Sbjct: 232 NNPKLTG 238
>Hs14249446 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP reductase
Length = 179
Score = 72.0 bits (175), Expect = 9e-13
Identities = 60/189 (31%), Positives = 94/189 (48%), Gaps = 13/189 (6%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVT 90
KV V G S GIG AVA+ +A+ G LAV + A +L + +A+ C V
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH----LAFSCDVA 58
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVY 150
+E V+ T E++ + G+++ + AG+ G LV T T++ +HT+ G
Sbjct: 59 KEHDVQNTFEEMEKHLGRVNFLVNAAGIN-RDGLLVR-----TKTEDMVSQLHTNLLGSM 112
Query: 151 YCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA-GF 209
K +Q GS+V S+ G N Q+ Y+A+K G++ F+++LA E A
Sbjct: 113 LTCKAAMRTMIQQQGGSIVNVGSIVGLKGN--SGQSVYSASKGGLVGFSRALAKEVARKK 170
Query: 210 ARVNTVSPG 218
RVN V+PG
Sbjct: 171 IRVNVVAPG 179
>7293522 [Q] KOG1207 Diacetyl reductase/L-xylulose reductase
Length = 242
Score = 70.9 bits (172), Expect = 2e-12
Identities = 75/261 (28%), Positives = 115/261 (43%), Gaps = 33/261 (12%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L GKV +VTGA +GIG A+ + LA AGA++ A+ + +L V Q
Sbjct: 5 LAGKVILVTGAGAGIGQALVKQLASAGATV-------IAVARKPEQLQQLVAFDPVHIQ- 56
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
P+ + + + + + + +D + NAGV K P E E DT H D N
Sbjct: 57 PLQLDLSGWQAVREGLAKVPLLDGLVNNAGVAIIK-PFEELTEQDFDT-------HFDVN 108
Query: 148 --GVYYCAKYVGAQFKRQGS----GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
V+ + + + K S S+ + S GH Y+A KA + KS
Sbjct: 109 IKAVFNVTQSLLPRLKDGASIVNVSSIASSRSFGGH--------TAYSATKAALDSLTKS 160
Query: 202 LAVEWA-GFARVNTVSPGYIATPI--SNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYF 258
LA+E RVN+V+P + T + N+ D + IP+ R QE+V A Y
Sbjct: 161 LALELGPRKIRVNSVNPTVVLTKMGADNWSDPAKSGPLLAHIPLNRFCEVQEVVDATGYL 220
Query: 259 ASDASTYTTGSDLLVDGAYCV 279
S S++ G +L++G Y V
Sbjct: 221 LSSKSSFVNGHHILLEGGYSV 241
>At5g04900 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 341
Score = 70.1 bits (170), Expect = 3e-12
Identities = 61/207 (29%), Positives = 101/207 (48%), Gaps = 32/207 (15%)
Query: 34 VVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVE-LSAKYNVKVVAYQCPVTEE 92
++TG++ GIGYA+A +AG ++ + S A VE AV+ L ++ V +C VTE
Sbjct: 83 LITGSTKGIGYALAREFLKAGDNVVICSRS-AERVETAVQSLKEEFGEHVWGTKCDVTEG 141
Query: 93 AKVKKTIEDVIQEFGKIDVFIANAGV-PWTKGPLVEAAESGTDTDEWNKVIHTDFNGVYY 151
V++ + + ID++I NAG ++ PL EA++ ++ +V+ T+ G+
Sbjct: 142 KDVRELVAYSQKNLKYIDIWINNAGSNAYSFKPLAEASD-----EDLIEVVKTNTLGLML 196
Query: 152 CAKYVGAQFKRQGSGSMVITASMSGHIVNI----------PQLQACYNAAKAGVIHFAKS 201
C + + +M++T S GHI NI P+ A Y A K V+H KS
Sbjct: 197 CCR---------EAMNMMLTQSRGGHIFNIDGAGSDGRPTPRF-AAYGATKRSVVHLTKS 246
Query: 202 LAVEW----AGFARVNTVSPGYIATPI 224
L E V+ +SPG + T +
Sbjct: 247 LQAELQMQDVKNVVVHNLSPGMVTTDL 273
>7293420 [Q] KOG1199 Short-chain alcohol dehydrogenase/3-hydroxyacyl-CoA
dehydrogenase
Length = 255
Score = 70.1 bits (170), Expect = 3e-12
Identities = 74/257 (28%), Positives = 119/257 (45%), Gaps = 16/257 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
+K V++VTG +SG+G A AE LA+ GAS+ + ++ E A EL KVV
Sbjct: 2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGD----KVVFVPV 57
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTD-- 145
VT E V ++ +FG++D+ + AG +++ +VI+ +
Sbjct: 58 DVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTV 117
Query: 146 --FNGVYYCAKYVGAQFKRQGS--GSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
FN + A +GA Q G +V TAS++ I QA Y+A+KA V+
Sbjct: 118 GTFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIG--QAAYSASKAAVVGMTLP 175
Query: 202 LAVEWAGFA-RVNTVSPGYIATPISNFVDEDLKNKWHSLIPM-GREGLPQELVGAYLYFA 259
+A + + R+ T++PG TP+ + E ++ IP R G P E A+L A
Sbjct: 176 IARDLSTQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEY--AHLVQA 233
Query: 260 SDASTYTTGSDLLVDGA 276
+ G + +DGA
Sbjct: 234 IYENPLLNGEVIRIDGA 250
>7297069 [Q] KOG1205 Predicted dehydrogenase
Length = 246
Score = 69.3 bits (168), Expect = 6e-12
Identities = 57/204 (27%), Positives = 99/204 (47%), Gaps = 13/204 (6%)
Query: 29 KGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCP 88
+ K+AVVTGAS GIG A A + AG + A L E L + + +C
Sbjct: 5 QNKLAVVTGASGGIGAACARAMIGAGLRVVGLARREAKLKELRESLPRELQANFIPRRCD 64
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNG 148
V++E +V+ + + + +E DV + NAG+ + LV + ++T + +VI T+ G
Sbjct: 65 VSKEDQVQSSFDWIERELEGADVLLNNAGIT-RETELV----TPSNTQKLKEVIDTNVMG 119
Query: 149 VYYCAKYVGAQFKRQ-GSGSMVITASMSGH-IVNIPQLQACYN---AAKAGVIHFAKSLA 203
V +C + KR+ G G ++I S++GH ++N + +N A K + ++
Sbjct: 120 VIWCTREAFNNMKRRGGEGHVLIINSIAGHQVLNFIDVLPSFNIYPATKFAITAITETYR 179
Query: 204 VEW---AGFARVNTVSPGYIATPI 224
E+ + RV + PG + T I
Sbjct: 180 QEFQLHSNKIRVTGICPGAVNTNI 203
>CE21093 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 281
Score = 68.6 bits (166), Expect = 1e-11
Identities = 67/266 (25%), Positives = 115/266 (43%), Gaps = 21/266 (7%)
Query: 25 LFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL--SAKYNVKV 82
L GKVA+VTG+S+GIG A A A+ GA + V + L E E+ S V
Sbjct: 2 LSRFSGKVALVTGSSNGIGRAAAVLFAKDGAKVTVTGRNAERLEETRQEILKSGVPESHV 61
Query: 83 VAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTD--EWNK 140
++ + E + + IQ+FG++D+ + NAG + + G D D ++K
Sbjct: 62 LSVATDLAAEKGQDELVNSTIQKFGRLDILVNNAGAAFND----DQGRVGVDQDVSVYDK 117
Query: 141 VIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAK 200
++ + V + + G +V +S++G P + Y +K+ + F +
Sbjct: 118 IMQINMRSVVTLTQKAKEHLVK-AKGEIVNVSSIAGTAHAQPGVM-YYAMSKSALDQFTR 175
Query: 201 SLAVEWAGF-ARVNTVSPGYIATPI-------SNFVDEDLK--NKWHSLIPMGREGLPQE 250
A++ + RVN+VSPG + T S +E +K IP G P +
Sbjct: 176 CAAIDLIQYGVRVNSVSPGGVTTGFGEAMGMPSGAFEEMMKFMESRKECIPSGAVAKPID 235
Query: 251 LVGAYLYFAS-DASTYTTGSDLLVDG 275
+ + A S+Y G ++ DG
Sbjct: 236 IANIIAFLADRKLSSYIIGQSIVADG 261
>CE20725 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 279
Score = 67.8 bits (164), Expect = 2e-11
Identities = 66/262 (25%), Positives = 111/262 (42%), Gaps = 23/262 (8%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL--SAKYNVKVVAYQC 87
GKVA++TG+S+GIG A A AQ GA + + + L E E+ S ++A
Sbjct: 6 GKVALITGSSNGIGRAAAILFAQQGAKVTITGRNAERLKETRHEIKKSGIPAENILAIVA 65
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEA-AESGTDTD--EWNKVIHT 144
V + + I D +++FG +D+ + NAG G L++A G D D ++ +
Sbjct: 66 DVITDEGQMRLINDTVRKFGHLDILVNNAG-----GALMDAQGRVGMDQDISVFDNTMQI 120
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ V + + + ++A +GH + + Y +KA + F +S A+
Sbjct: 121 NMRSVVTLVQKAKEHLIKSKGEIINVSAMAAGH--HGDPIATFYGMSKAALDQFTRSSAI 178
Query: 205 EWAGF-ARVNTVSPGYIAT---------PISNFVDEDLKNKWHSLIPMGREGLPQELVGA 254
RVN+VSPG+ T PI+ P G P ++
Sbjct: 179 SLIQHGVRVNSVSPGFTKTGFGEAMGFPPIAMKKVISFYESHKECAPSGAIAQPGDIAQV 238
Query: 255 YLYFAS-DASTYTTGSDLLVDG 275
L+ A S+Y G ++ DG
Sbjct: 239 ILFLADRTMSSYIIGQSIIADG 260
>7301818 [Q] KOG1205 Predicted dehydrogenase
Length = 326
Score = 67.4 bits (163), Expect = 2e-11
Identities = 61/204 (29%), Positives = 99/204 (47%), Gaps = 16/204 (7%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGAS--LAVWYNSNAALVER---AVELSAKYNVKV 82
L GKV ++TGASSG+G ++A +AG LA V++ A+++ Y V
Sbjct: 51 LPGKVVLITGASSGLGESLAHVFYRAGCRVILAARRTQELERVKKDLLALDVDPAYPPTV 110
Query: 83 VAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVI 142
+ + E + + + V+ + ++D+ I N G+ V A + T D KV+
Sbjct: 111 LPLD--LAELNSIPEFVTRVLAVYNQVDILINNGGIS------VRADVASTAVDVDLKVM 162
Query: 143 HTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSL 202
++ G K + ++GSG + +S+ G IPQ +A Y+A+K + FA SL
Sbjct: 163 VVNYFGSVALTKALLPSMVKRGSGHICFISSVQGKFA-IPQ-RAAYSASKHAMQAFADSL 220
Query: 203 AVEWAG-FARVNTVSPGYIATPIS 225
E A V+ VSPGYI T +S
Sbjct: 221 RAEVANKNINVSCVSPGYIRTQLS 244
>CE03954 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 274
Score = 66.2 bits (160), Expect = 5e-11
Identities = 70/270 (25%), Positives = 108/270 (39%), Gaps = 40/270 (14%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVE--RAVELSAKYNVKVVAYQCP 88
KVA++TG+S+GIG A A LA GA + + A L E +A+ + V +
Sbjct: 7 KVAIITGSSNGIGRATAVLLATDGAKVTITGRDAARLEETRQAILKAGISATNVNSVVAD 66
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAG--VPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
VT I + +FGKI++ I NAG +P ++G + + K+ +
Sbjct: 67 VTTAEGQDLLISSTLDKFGKINILINNAGANIPDSQG----QTRTKCSIENLTKMFQLNL 122
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQA---------CYNAAKAGVIH 197
V + V A G IVNI + A Y++AKA +
Sbjct: 123 QSVVEMVQKVRPHL-----------AKTRGEIVNISSIGAGPAAQPASPYYSSAKAALDQ 171
Query: 198 FAKSLAVEWAGFA-RVNTVSPGYIATPISN-----FVDE-----DLKNKWHSLIPMGREG 246
+++ A++ R+N V PG+++T S DE DL IP G G
Sbjct: 172 YSRCAAIDLISEGIRINVVQPGFVSTGFSTAARGLSADESVKFYDLMGSLPHCIPAGYCG 231
Query: 247 LPQELVGAYLYFAS-DASTYTTGSDLLVDG 275
P L + S Y G ++ DG
Sbjct: 232 QPDHLASVIAFLVDRKVSEYIVGQTIIADG 261
>At1g49670_1 [IR] KOG4169 15-hydroxyprostaglandin dehydrogenase and related
dehydrogenases
Length = 305
Score = 66.2 bits (160), Expect = 5e-11
Identities = 54/211 (25%), Positives = 91/211 (42%), Gaps = 12/211 (5%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAV---ELSAKYNV-----K 81
G A+VTG +SGIG A+ LA+ G + V S E E +AK++
Sbjct: 6 GLSALVTGGASGIGRALCLALAEKGVFVTVADFSEEKGQETTSLVREANAKFHQGLSFPS 65
Query: 82 VVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKV 141
+ +C VT + + + FG +D+ I NAG+ PL + + W
Sbjct: 66 AIFVKCDVTNRGDLLAAFDKHLATFGTLDICINNAGI---STPLRFDKDDTDGSKSWKHT 122
Query: 142 IHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
I+ D V + K + ++I + + +P + Y A+KAGV+ F +S
Sbjct: 123 INVDLIAVVEGTQLAIKAMKAKQKPGVIINMGSAAGLYPMP-VDPIYAASKAGVVLFTRS 181
Query: 202 LAVEWAGFARVNTVSPGYIATPISNFVDEDL 232
LA R+N + P +I T ++ +D +
Sbjct: 182 LAYYRRQGIRINVLCPEFIKTDLAEAIDASI 212
>At5g50690 [Q] KOG1205 Predicted dehydrogenase
Length = 303
Score = 65.9 bits (159), Expect = 6e-11
Identities = 56/202 (27%), Positives = 100/202 (48%), Gaps = 14/202 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAAL---VERAVELSAKYNVKVVA 84
+ GKV ++TG+SSGIG +A A+ GA L + L +R +L + +V VV
Sbjct: 45 VNGKVVIITGSSSGIGEHLAYEYARRGAYLTLVARREDRLQVVADRCRKLGSP-DVAVVR 103
Query: 85 YQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
V ++ K+ +++ I FG++D + NAG+ K E ++ + +++T
Sbjct: 104 GDVSVIKDC--KRFVQETISRFGRLDHLVNNAGIAEAK-----FFEDYSEISDVLPIVNT 156
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+F G Y + K+ G ++ AS +G +P++ + Y A+KA +I+F ++L +
Sbjct: 157 NFWGPVYATHFAIPHLKKT-KGKIIAVASPAGW-SGVPRM-SIYAASKAAMINFYETLRI 213
Query: 205 EWAGFARVNTVSPGYIATPISN 226
E V V PG I +N
Sbjct: 214 ELHPEVGVTIVFPGLIENGNTN 235
>At5g50590 [Q] KOG1205 Predicted dehydrogenase
Length = 299
Score = 65.9 bits (159), Expect = 6e-11
Identities = 56/202 (27%), Positives = 100/202 (48%), Gaps = 14/202 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAAL---VERAVELSAKYNVKVVA 84
+ GKV ++TG+SSGIG +A A+ GA L + L +R +L + +V VV
Sbjct: 45 VNGKVVIITGSSSGIGEHLAYEYARRGAYLTLVARREDRLQVVADRCRKLGSP-DVAVVR 103
Query: 85 YQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
V ++ K+ +++ I FG++D + NAG+ K E ++ + +++T
Sbjct: 104 GDVSVIKDC--KRFVQETISRFGRLDHLVNNAGIAEAK-----FFEDYSEISDVLPIVNT 156
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+F G Y + K+ G ++ AS +G +P++ + Y A+KA +I+F ++L +
Sbjct: 157 NFWGPVYATHFAIPHLKKT-KGKIIAVASPAGW-SGVPRM-SIYAASKAAMINFYETLRI 213
Query: 205 EWAGFARVNTVSPGYIATPISN 226
E V V PG I +N
Sbjct: 214 ELHPEVGVTIVFPGLIENGNTN 235
>At4g10020 [Q] KOG1205 Predicted dehydrogenase
Length = 389
Score = 65.9 bits (159), Expect = 6e-11
Identities = 57/230 (24%), Positives = 110/230 (47%), Gaps = 17/230 (7%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAAL---VERAVELSAKYNVKVV 83
+++ KV V+TGASS IG +A A+ GA+L + L +A ++ A + V+
Sbjct: 46 NMEDKVVVITGASSAIGEQIAYEYAKRGANLVLVARREQRLRVVSNKAKQIGANH---VI 102
Query: 84 AYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
V +E ++ I + +G++D + A + T E +DT + ++
Sbjct: 103 IIAADVIKEDDCRRFITQAVNYYGRVDHLVNTASLGHT-----FYFEEVSDTTVFPHLLD 157
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLA 203
+F G Y YV + Q +G +V+ AS+ + +P++ + Y+AAKA +++F ++L
Sbjct: 158 INFWGNVY-PTYVALPYLHQTNGRIVVNASVENWL-PLPRM-SLYSAAKAALVNFYETLR 214
Query: 204 VEWAGFARVNTVSPGYIATPISN---FVDEDLKNKWHSLIPMGREGLPQE 250
E G + + G+I + +S ++E + +W + G P E
Sbjct: 215 FELNGDVGITIATHGWIGSEMSGGKFMLEEGAEMQWKEEREVPANGGPLE 264
>CE06649 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 284
Score = 65.5 bits (158), Expect = 8e-11
Identities = 75/266 (28%), Positives = 116/266 (43%), Gaps = 29/266 (10%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVK---VVAYQ 86
GKV +++G+S GIG A A A GA + V +A VE+ +L + K ++
Sbjct: 8 GKVVLISGSSKGIGQATAVKFAAEGAKI-VLNGRSADDVEKTRKLCMEVGAKPWDLLPTV 66
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDE--WNKVIHT 144
+T E VK + VI FGK+D+ I NAG E E G D + WN +
Sbjct: 67 GDITNEDFVKMMVNTVIHNFGKLDILINNAGTLEVDMTGKEGWEMGVDVMDRSWN----S 122
Query: 145 DFNGVYYCAKYVGAQ-FKRQGSGSMVITASMSGHI--VNIPQLQACYNAAKAGVIHFAKS 201
+F V + K +G V T SG I +++P Y KA + ++S
Sbjct: 123 NFKSVLMLTQAAMPHLIKTKGDIVNVSTFLSSGPIGVMSMPY----YAVPKAALDQMSRS 178
Query: 202 LAVEW-AGFARVNTVSPGYIATPI---SNFVDEDLKNKWHS-------LIPMGREGLPQE 250
+A E+ R+NTV+PG ++T V +D K + IP+GR +
Sbjct: 179 MAHEYMLKGVRLNTVNPGLVSTSFFARLPGVGDDNARKMENYVQSKTEYIPLGRVCQASD 238
Query: 251 LVGAYLYFAS-DASTYTTGSDLLVDG 275
+ L+ A S G +++DG
Sbjct: 239 VAETILFLADRKVSECIVGQSIIIDG 264
>CE03132 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 278
Score = 65.5 bits (158), Expect = 8e-11
Identities = 66/268 (24%), Positives = 111/268 (40%), Gaps = 36/268 (13%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVE--RAVELSAKYNVKVVAYQCP 88
KVA++TG+SSGIG A A+ GA + V S L E +A+ + +
Sbjct: 8 KVAIITGSSSGIGRETALLFAKEGAKVTVTGRSEEKLEETKKALLDAGIKESNFLIVPAD 67
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNG 148
+T + I +++FG+I++ + NAG + G +T + +V+ +
Sbjct: 68 ITFSTGQDELISQTLKKFGRINILVNNAGASIPDAKKRTGIDQGIET--YEQVMKLNVQS 125
Query: 149 VYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQAC---------YNAAKAGVIHFA 199
V + V A G IVN+ + A Y AKA + +
Sbjct: 126 VIEMTQKVRPHL-----------AKSRGEIVNVSSVVALKAGWTRTPYYPLAKAALDQYT 174
Query: 200 KSLAVEWAGFA-RVNTVSPGYIATPI----SNFVDEDLKNKWHSL------IPMGREGLP 248
+S A+ RVNTV+PG + T S +D + + + IP G G P
Sbjct: 175 RSAAIALISEGIRVNTVNPGIVQTGFQANASGSSSDDAQKFYDDMGSNTTAIPCGFAGRP 234
Query: 249 QELVGAYLYFAS-DASTYTTGSDLLVDG 275
+ + A + A ++S Y G +++ DG
Sbjct: 235 EHIAKAIAFLADRNSSEYIVGQNIIADG 262
>CE15574 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 279
Score = 65.1 bits (157), Expect = 1e-10
Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 17/259 (6%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL--SAKYNVKVVAYQC 87
GKVA+VTG+S+GIG A A LA+ GA + + + L E E+ S V++
Sbjct: 6 GKVALVTGSSNGIGRATAILLAREGAKVTITGRNAQRLEETKQEILRSGVPEDHVLSIIA 65
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
+ E+ + + + FG++D+ + NAG T L GT+ ++K + +
Sbjct: 66 DLATESGQIELMNSTVDIFGRLDILVNNAGAAIT--DLEGHIGVGTNVSVFDKTMRINLR 123
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
V + + G +V +S++G P+L Y +K+ + + +S A++
Sbjct: 124 SVVTLTQKAKEHLIKT-KGEIVNVSSIAGGQHAQPEL-IYYAMSKSALDQYTRSAAIDLI 181
Query: 208 GF-ARVNTVSPGYIATPISNFV---DEDLKNKWHSL------IPMGREGLPQELVGAYLY 257
RVN+VSPG I T I + E ++N + + P+G P ++ ++
Sbjct: 182 QHGVRVNSVSPGDIRTGIYETMGMNKESVENIYKFMESRKECCPIGTIAQPVDVANIIVF 241
Query: 258 FAS-DASTYTTGSDLLVDG 275
A S+Y G ++ DG
Sbjct: 242 LADRKLSSYIIGQSIVADG 260
>SPAC521.03 [Q] KOG1205 Predicted dehydrogenase
Length = 259
Score = 63.9 bits (154), Expect = 2e-10
Identities = 55/200 (27%), Positives = 94/200 (46%), Gaps = 9/200 (4%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQ-AGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
L GK ++TGASSGIG + A +A+ A L + + + E A EL +KY V V+ +
Sbjct: 4 LDGKTILITGASSGIGKSTAFEIAKVAKVKLILAARRFSTVEEIAKELESKYEVSVLPLK 63
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
V++ + IE + +EF IDV I NAG+ +++ + D+ +I T+
Sbjct: 64 LDVSDLKSIPGVIESLPKEFADIDVLINNAGLALGTDKVID-----LNIDDAVTMITTNV 118
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
G+ + V F + G ++ S++G + + Y + K+ + F +L E
Sbjct: 119 LGMMAMTRAVLPIFYSKNKGDILNVGSIAGRESYVG--GSVYCSTKSALAQFTSALRKET 176
Query: 207 AGF-ARVNTVSPGYIATPIS 225
R+ V PG + T S
Sbjct: 177 IDTRIRIMEVDPGLVETEFS 196
>CE28758 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 253
Score = 63.9 bits (154), Expect = 2e-10
Identities = 65/256 (25%), Positives = 110/256 (42%), Gaps = 25/256 (9%)
Query: 33 AVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKV----VAYQCP 88
A+V GA+S +G AV LA G +A AA +V A+ N+KV A+
Sbjct: 4 ALVIGATSTLGKAVVRRLAFTGYKVAA-----AADCPNSVGKVAEDNIKVGGDVTAFSLD 58
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNG 148
V K+ I V ++ G +D I G ++E T ++++K+ +
Sbjct: 59 VANAEHRKELITKVAEKLGGLDTLIIVPPQNEVLGEIIE-----TSGEDFDKLFANNLTT 113
Query: 149 VYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAG 208
+ ++ + + +GS++ S G +I Y+ A + V+ KS+A A
Sbjct: 114 PFRLSQAAMSTLAKSQNGSIIYLTSCFGFTPSIDM--GLYSVASSSVLSLTKSVAQSAAK 171
Query: 209 FA-RVNTVSPGYIATPISNFVDE--------DLKNKWHSLIPMGREGLPQELVGAYLYFA 259
RVN+V G I + V + +K S+IP+GR G P ++ + A
Sbjct: 172 QGVRVNSVVSGMIEGDGTGAVWDHASGEEARQIKQHLESMIPLGRLGRPSDVASYVEFLA 231
Query: 260 SDASTYTTGSDLLVDG 275
S + Y TG + +V G
Sbjct: 232 STKARYITGENCIVGG 247
>At1g52340 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 285
Score = 63.9 bits (154), Expect = 2e-10
Identities = 63/271 (23%), Positives = 110/271 (40%), Gaps = 35/271 (12%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY-- 85
L GKVA++TG ++GIG ++ + GA + + + L + + K A+
Sbjct: 18 LLGKVALITGGATGIGESIVRLFHKHGAKVCI-VDLQDDLGGEVCKSLLRGESKETAFFI 76
Query: 86 QCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTD 145
V E + ++ ++ FG +D+ I NAG+ P + E+ +
Sbjct: 77 HGDVRVEDDISNAVDFAVKNFGTLDILINNAGLCGAPCPDIR----NYSLSEFEMTFDVN 132
Query: 146 FNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
G + K+ + GS+V S+ G + + Y +K V+ +S+A E
Sbjct: 133 VKGAFLSMKHAARVMIPEKKGSIVSLCSVGGVVGGVGPHS--YVGSKHAVLGLTRSVAAE 190
Query: 206 WAGFA-RVNTVSPGYIATPIS------------------NFVDEDLKNKWHSLIPMGREG 246
RVN VSP +AT ++ NF + K G E
Sbjct: 191 LGQHGIRVNCVSPYAVATKLALAHLPEEERTEDAFVGFRNFAAANANLK-------GVEL 243
Query: 247 LPQELVGAYLYFASDASTYTTGSDLLVDGAY 277
++ A L+ ASD S Y +G +L++DG +
Sbjct: 244 TVDDVANAVLFLASDDSRYISGDNLMIDGGF 274
>CE27260 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 206
Score = 63.2 bits (152), Expect = 4e-10
Identities = 61/213 (28%), Positives = 101/213 (46%), Gaps = 32/213 (15%)
Query: 32 VAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL----SAKYNVKVVAYQC 87
VA+VTGASSGIG A A LA+ L++ + AAL E A ++ S K +V V A +
Sbjct: 3 VAIVTGASSGIGRAAALLLARNNYKLSLTGRNVAALNELAGQIVSAGSDKNDVLVTAVE- 61
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
+ E K ++ +Q+FG+ID I +AG+ GP++++ + ++++++ +
Sbjct: 62 -LASEEAPKTIVDATVQKFGRIDTLINSAGI-LRAGPVLDSG-----IEVYDELMNVNVR 114
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQ--------ACYNAAKAGVIHFA 199
+ R ++ + G +VN+ + Y +K+ V F
Sbjct: 115 SLI-----------RLTRAALPHIITTKGTVVNVSSINGPCPFAGVTYYCMSKSAVDQFT 163
Query: 200 KSLAVEWA-GFARVNTVSPGYIATPISNFVDED 231
K LA+E A RVN V PG I T I +D
Sbjct: 164 KCLALEMAPNGVRVNAVCPGVIVTNIHRASGQD 196
>CE06316 [Q] KOG1207 Diacetyl reductase/L-xylulose reductase
Length = 251
Score = 62.8 bits (151), Expect = 5e-10
Identities = 67/243 (27%), Positives = 106/243 (43%), Gaps = 18/243 (7%)
Query: 40 SGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL-SAKYNVKVVAYQCPVTEEAKVKKT 98
+GIG + LA+AGA + + + A L+ E S +Y + + EE K
Sbjct: 19 AGIGKEICLSLAKAGAQVIAFARNEANLLSLVKETTSLRYTIIPIVGDVSANEEVLFKL- 77
Query: 99 IEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVYYCAKYVGA 158
++ F I + NAG+ T + + + D + + G A+ V
Sbjct: 78 ---IVPHF-PIHGLVNNAGIA-TNHAIGQITQQSID-----RTFAVNVRGPILIAQLVAR 127
Query: 159 QF-KRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAGF-ARVNTVS 216
F RQ GS+V +S + + Y A+KA + + LA E RVN+V+
Sbjct: 128 NFVDRQIKGSIVNISSQAA--IRPLDNHTVYCASKAALDMVTRCLANELGSQNIRVNSVN 185
Query: 217 PGYIATPIS--NFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDASTYTTGSDLLVD 274
P + T + N+ D D K K +P+ R E+V A L+ SD ++ TTGS L VD
Sbjct: 186 PTVVMTDMGRDNWSDPDKKKKMLDRMPIKRFAEVDEVVNAVLFLLSDNASMTTGSTLPVD 245
Query: 275 GAY 277
G +
Sbjct: 246 GGF 248
>At5g10050 [Q] KOG1209 1-Acyl dihydroxyacetone phosphate reductase and related
dehydrogenases
Length = 299
Score = 62.8 bits (151), Expect = 5e-10
Identities = 59/211 (27%), Positives = 94/211 (43%), Gaps = 24/211 (11%)
Query: 32 VAVVTGASSG-IGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVT 90
V ++TG S G IG+A+A + G + S + + + +E ++ VK + V
Sbjct: 9 VVLITGCSQGGIGHALAREFTEKGCRVVATSRSRSTMTD--LEQDSRLFVK----ELDVQ 62
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVY 150
+ V K + +VI +FGKIDV + NAGV GPL E S + + +N + + + ++
Sbjct: 63 SDQNVSKVLSEVIDKFGKIDVLVNNAGVQCV-GPLAETPISAME-NTFNTNVFGNKDLIF 120
Query: 151 YCAKYVGAQFKRQGSGSMV------ITASMSGHIVNIPQL--------QACYNAAKAGVI 196
Y+ F GS M + + G IVN+ + Y A KA +
Sbjct: 121 SFNYYIYWSFNSSGSMRMTQAVVPHMVSKKKGKIVNVGSITVMAPGPWAGVYTATKAAIH 180
Query: 197 HFAKSLAVEWAGFA-RVNTVSPGYIATPISN 226
+L +E F V V PG I T I+N
Sbjct: 181 ALTDTLRLELRPFGIDVINVVPGGIRTNIAN 211
>CE06423 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 307
Score = 62.4 bits (150), Expect = 7e-10
Identities = 50/188 (26%), Positives = 87/188 (45%), Gaps = 9/188 (4%)
Query: 18 LASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAK 77
L + VL S++GK ++TG+ SGIG +A A+ GA + +W + N E K
Sbjct: 27 LPNGVLPRKSVEGKKVLITGSGSGIGRLMALEFAKLGAEVVIW-DVNKDGAEETKNQVVK 85
Query: 78 YNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDE 137
K + +++ + K ++ + G ID+ I NAG+ T L + + +
Sbjct: 86 AGGKASTFVVDLSQYKDIHKVAKETKEAVGDIDILINNAGIV-TGKKLFDCPD-----EL 139
Query: 138 WNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIH 197
K + + N ++Y AK + +G +V ASM+G + + C A+K G I
Sbjct: 140 MEKTMAVNTNALFYTAKNFLPSMLEKDNGHLVTIASMAGKTGCVGLVDYC--ASKHGAIG 197
Query: 198 FAKSLAVE 205
S+A+E
Sbjct: 198 CHDSIAME 205
>7292690 [Q] KOG1205 Predicted dehydrogenase
Length = 251
Score = 62.4 bits (150), Expect = 7e-10
Identities = 55/201 (27%), Positives = 90/201 (44%), Gaps = 11/201 (5%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVT 90
+VAVVTGASSGIG A + L G + L E L A + +C V+
Sbjct: 7 RVAVVTGASSGIGAACCKDLVSKGLVVVGLARREDRLQELKASLPADQASRFHGRKCDVS 66
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVY 150
+E +V + G DV + NAG+ G + +G D ++ T+ GV
Sbjct: 67 QEQEVIDAFAWIDATLGGADVLVNNAGIV-RLGVGITHEGNGADL---RAILDTNVLGVS 122
Query: 151 YCAKYVGAQFKRQ--GSGSMVITASMSGH-IVNIPQL-QACYNAAKAGVIHFAKSLAVEW 206
+C + KR+ G ++I S++GH ++N P + Y+ +K V + L E+
Sbjct: 123 WCTREAFKSLKRRNVNDGHILIVNSVAGHRVINNPGITMGMYSPSKYAVTALTEVLRQEF 182
Query: 207 AG---FARVNTVSPGYIATPI 224
++ ++SPG + T I
Sbjct: 183 HNNKTQTKITSISPGAVDTEI 203
>7300944 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 321
Score = 62.0 bits (149), Expect = 9e-10
Identities = 50/200 (25%), Positives = 92/200 (46%), Gaps = 12/200 (6%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
S+ G+VAVVTGA G+G A++ LA+ G +AV + + + ++ Y V+ AY+
Sbjct: 49 SIAGEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQIQDIYKVRAKAYK 108
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
VT + + V++E G + V + NAGV ++ D + +I+ +
Sbjct: 109 ANVTNYDDLVELNSKVVEEMGPVTVLVNNAGV------MMHRNMFNPDPADVQLMINVNL 162
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
++ + K G +V +S++G + +P A Y K+G + ++L +E
Sbjct: 163 TSHFWTKLVFLPKMKELRKGFIVTISSLAG-VFPLP-YSATYTTTKSGALAHMRTLRMEL 220
Query: 207 ----AGFARVNTVSPGYIAT 222
V TV P ++ T
Sbjct: 221 DLENQKDIHVTTVLPSFLRT 240
>7295622 [Q] KOG1205 Predicted dehydrogenase
Length = 247
Score = 61.6 bits (148), Expect = 1e-09
Identities = 59/206 (28%), Positives = 98/206 (46%), Gaps = 21/206 (10%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAG---ASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
+VAVVTGASSGIG AVA L AG LA + A+ E +L + ++ A C
Sbjct: 7 RVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKE---QLPPELQGRLHAIHC 63
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V + V + + ++ G D+ + NAG G L+ + ++ +V++ +
Sbjct: 64 DVEDLDSVTAAFDWIEEQLGGCDILVNNAGC-LNPGQLLT-----LELEQLQQVLNVNLM 117
Query: 148 GVYYCAKYV-GAQFKRQGSGSMVITASMSG-HIVNIP----QLQACYNAAKAGVIHFAKS 201
GV C + + +R+ G +++ S++G +I+N P Q+ Y K GV +
Sbjct: 118 GVVICTRRAFRSMQQREVDGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEV 177
Query: 202 LAVEWAGF---ARVNTVSPGYIATPI 224
L E GF +V +++PG T I
Sbjct: 178 LRQELRGFKTKIKVTSITPGVTDTEI 203
>CE27259 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 501
Score = 60.5 bits (145), Expect = 3e-09
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 16/205 (7%)
Query: 32 VAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL----SAKYNVKVVAYQC 87
VA+VTGASSGIG A A LA+ L++ + AAL E A ++ S K +V V A +
Sbjct: 3 VAIVTGASSGIGRAAALLLARNNYKLSLTGRNVAALNELAGQIVSAGSDKNDVLVTAVE- 61
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
+ E K ++ +Q+FG+ID I +AG+ GP++++ + ++++++ +
Sbjct: 62 -LASEEAPKTIVDATVQKFGRIDTLINSAGI-LRAGPVLDSG-----IEVYDELMNVNVR 114
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
+ + G++V +S++G P + Y +K+ V F K LA+E A
Sbjct: 115 SLIRLTR-AALPHIITTKGTVVNVSSINGP-CPFPNV-TYYCMSKSAVDQFTKCLALEMA 171
Query: 208 -GFARVNTVSPGYIATPISNFVDED 231
RVN V PG T + +D
Sbjct: 172 PNGVRVNAVCPGVTVTNLHRTSGQD 196
>At3g03330 [Q] KOG1205 Predicted dehydrogenase
Length = 345
Score = 60.1 bits (144), Expect = 3e-09
Identities = 57/202 (28%), Positives = 89/202 (43%), Gaps = 14/202 (6%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKY---NVKVV 83
+++GKV +TGAS GIG +A+ A A L + + A L EL K+ +VKV+
Sbjct: 40 AIQGKVVWITGASRGIGEILAKQFASLDAKLILSARNKAELDRVKSELKGKFAPEDVKVL 99
Query: 84 AYQCPVTEEAKVKKTIEDVIQEF--GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKV 141
EE+ +K +E + F +D + NA K +A+E T
Sbjct: 100 PLDLASGEES-LKHVVEQAVSLFPGAGVDYLVHNAAFERPKSKASDASEETLKT-----T 153
Query: 142 IHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
+ G K V +QG G V+ +S +G + + QA Y+A+K + + S
Sbjct: 154 FDVNVFGTISLTKLVAPHMLKQGGGHFVVISSAAGKVPS--PGQAIYSASKHALHGYFHS 211
Query: 202 LAVEWAGFA-RVNTVSPGYIAT 222
L E+ +V V PG I T
Sbjct: 212 LRSEFCQKGIKVTVVCPGPIET 233
>At3g06060 [Q] KOG1210 Predicted 3-ketosphinganine reductase
Length = 327
Score = 59.7 bits (143), Expect = 5e-09
Identities = 53/178 (29%), Positives = 83/178 (45%), Gaps = 9/178 (5%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
+K + A +TG SSGIG A+A A GA +++ S + L E + V+V +
Sbjct: 37 IKSRHAFITGGSSGIGLALAHRAASEGARVSILARSGSKLEEAKKSIQLATGVEVATFSA 96
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V + V K I+ E G IDV I N GV K + + E T + N V FN
Sbjct: 97 DVRDYDAVSKAID----ESGPIDVLIVNQGVFTAKELVKHSPEDVKFTIDVNLV--GSFN 150
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
+ + A+ K +G S+ + +S +G + A Y+A+K G+ A++L E
Sbjct: 151 VIKAALPAMKAR-KDRGPASISLVSSQAGQVGVYG--YAAYSASKFGLQGLAQALQQE 205
>YIR036c [Q] KOG1204 Predicted dehydrogenase
Length = 263
Score = 59.3 bits (142), Expect = 6e-09
Identities = 50/208 (24%), Positives = 96/208 (46%), Gaps = 12/208 (5%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVE-LSAKYNVKVVAYQC- 87
GKV ++TGAS GIG + + + + V+ A E ++ L +Y Y+
Sbjct: 2 GKVILITGASRGIGLQLVKTVIEEDDECIVY---GVARTEAGLQSLQREYGADKFVYRVL 58
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTD--EWNKVIHTD 145
+T+ ++++ +E++ Q+ GK+D +ANAG+ P+ ++S ++ D +W ++ +
Sbjct: 59 DITDRSRMEALVEEIRQKHGKLDGIVANAGM---LEPVKSISQSNSEHDIKQWERLFDVN 115
Query: 146 FNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
F + K ++ S SG V + Y +KA + HFA +A E
Sbjct: 116 FFSIVSLVALCLPLLKSSPFVGNIVFVS-SGASVKPYNGWSAYGCSKAALNHFAMDIASE 174
Query: 206 W-AGFARVNTVSPGYIATPISNFVDEDL 232
+ R ++PG + T + + E L
Sbjct: 175 EPSDKVRAVCIAPGVVDTQMQKDIRETL 202
>7298352 [I] KOG1014 17 beta-hydroxysteroid dehydrogenase type 3 HSD17B3
Length = 339
Score = 59.3 bits (142), Expect = 6e-09
Identities = 61/222 (27%), Positives = 102/222 (45%), Gaps = 17/222 (7%)
Query: 12 PQEPPKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERA 71
P P L ++D F G+ AVVTGA+ GIG A LA+ G +L + + L+
Sbjct: 55 PYFQPHLPRTLVDKF---GQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVT 111
Query: 72 VELSAKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAES 131
E+ ++Y VK + + AK ++ + + +E IDV I V G + E ES
Sbjct: 112 NEIESQYKVKT---KWIAADFAKGREVYDQIEKELAGIDVGILVNNV----GMMYEHPES 164
Query: 132 GTDTDE---WNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACY 188
E WN ++ + V + + Q + G++V S S + +P + Y
Sbjct: 165 LDLVSEDLLWN-LLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGS-SSELQPLPNM-TVY 221
Query: 189 NAAKAGVIHFAKSLAVEWAGF-ARVNTVSPGYIATPISNFVD 229
A+K V +F+K+L +E A V V P ++ T ++ + D
Sbjct: 222 AASKKFVTYFSKALELEVAEHNIHVQLVMPNFVVTKMNAYTD 263
>YIL124w [Q] KOG1209 1-Acyl dihydroxyacetone phosphate reductase and related
dehydrogenases
Length = 297
Score = 58.9 bits (141), Expect = 8e-09
Identities = 58/208 (27%), Positives = 102/208 (48%), Gaps = 19/208 (9%)
Query: 24 DLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELS----AKYN 79
+L S K+AVVTGAS GIGY V + LA+ G + + + A++ Y
Sbjct: 3 ELQSQPKKIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYK 62
Query: 80 VKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWN 139
+ + + VT ++ + D GK+D+ NAG T P ++A ++ ++
Sbjct: 63 LDISKPEEIVTFSGFLRANLPD-----GKLDLLYNNAGQSCT-FPALDATDAA--VEQCF 114
Query: 140 KVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
KV F + C + ++F + G++V T S++G +V+ P + Y+A+KA + +A
Sbjct: 115 KV--NVFGHINMCREL--SEFLIKAKGTIVFTGSLAG-VVSFP-FGSIYSASKAAIHQYA 168
Query: 200 KSLAVEWAGF-ARVNTVSPGYIATPISN 226
+ L +E F RV G +AT I++
Sbjct: 169 RGLHLEMKPFNVRVINAITGGVATDIAD 196
>YMR226c [Q] KOG1205 Predicted dehydrogenase
Length = 267
Score = 58.5 bits (140), Expect = 1e-08
Identities = 68/257 (26%), Positives = 111/257 (42%), Gaps = 25/257 (9%)
Query: 28 LKGKVAVVTGASSGIGYAVA-EGLAQAGASLAVWYNSNAALVERAVELSAKY-----NVK 81
L K ++TGAS+GIG A A E L + + + A +E+ EL N K
Sbjct: 11 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILA--ARRLEKLEELKKTIDQEFPNAK 68
Query: 82 VVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKV 141
V Q +T+ K+K IE++ QEF ID+ + NAG + + A T++ V
Sbjct: 69 VHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIA-----TEDIQDV 123
Query: 142 IHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
T+ + + V F+ + SG +V S++G + + Y A+K V F S
Sbjct: 124 FDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGR--DAYPTGSIYCASKFAVGAFTDS 181
Query: 202 LAVEWAGF-ARVNTVSPGYIATPIS----NFVDEDLKNKWHSLIPMGREGLPQELVGAYL 256
L E RV ++PG + T S +E KN + P+ + + +V
Sbjct: 182 LRKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLMADDVADLIV---- 237
Query: 257 YFASDASTYTTGSDLLV 273
+A+ T +D L+
Sbjct: 238 -YATSRKQNTVIADTLI 253
>Hs7705905 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 300
Score = 58.5 bits (140), Expect = 1e-08
Identities = 52/206 (25%), Positives = 85/206 (41%), Gaps = 18/206 (8%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
S+ G++ ++TGA GIG A A+ + L +W + L E A + KV +
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKG-LGAKVHTFV 91
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
+ + + + V E G + + + NAGV +T T E N + H
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAH--- 148
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEW 206
++ K + G +V AS +GH V++P L A Y ++K + F K+L E
Sbjct: 149 ---FWTTKAFLPAMTKNNHGHIVTVASAAGH-VSVPFLLA-YCSSKFAAVGFHKTLTDEL 203
Query: 207 AGFARV---------NTVSPGYIATP 223
A N V+ G+I P
Sbjct: 204 AALQITGVKTTCLCPNFVNTGFIKNP 229
>SPAC3G9.02 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 236
Score = 58.2 bits (139), Expect = 1e-08
Identities = 63/246 (25%), Positives = 105/246 (42%), Gaps = 20/246 (8%)
Query: 34 VVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVTEEA 93
++TG SSG+G +A+ +Q G + + L E LS + V +
Sbjct: 5 LITGGSSGLGKRIAQIWSQKGHQCHIVGRNEFHLKETLQSLSVAKGQQHTLTIADVQSDM 64
Query: 94 KVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVYYCA 153
K K+I + ++ ID + AGV L + T E + +I T+ +
Sbjct: 65 KNLKSIFESVE----IDTVVHAAGV------LQSSLCVRTSEKEIDSIICTNLVSAIKLS 114
Query: 154 KYVGAQFKRQGSGS---MVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAGFA 210
K ++ R + +++ S +P Y A+KAG+ F K LA E A
Sbjct: 115 KMAILEWFRNKNSERDRLILNISSRLSTYALPGTSV-YAASKAGLESFTKVLAAEVASKG 173
Query: 211 -RVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDASTYTTGS 269
RVN +SPGY+ TP+ + ++ +P+GR E+V A + + YTTG+
Sbjct: 174 IRVNAISPGYVDTPM---LSSQIRAIAEKKVPIGRLASTDEIVDACTFLLD--NRYTTGT 228
Query: 270 DLLVDG 275
L + G
Sbjct: 229 ILPITG 234
>YIR035c [Q] KOG1204 Predicted dehydrogenase
Length = 254
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/205 (26%), Positives = 95/205 (46%), Gaps = 15/205 (7%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVW--YNSNAALVERAVELSAKYNVKVVAYQC 87
GKV +VTG S GIG ++ + L V+ S A L + L KY +
Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKK----LKEKYGDRFFYVVG 57
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
+TE++ +K+ + ++ GKID +ANAGV P+ E D + W K+ +F
Sbjct: 58 DITEDSVLKQLVNAAVKGHGKIDSLVANAGV---LEPVQNVNE--IDVNAWKKLYDINFF 112
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
+ + K+ +G++V +S + ++ Y ++KA + HFA +LA E
Sbjct: 113 SIVSLVGIALPELKKT-NGNVVFVSSDACNMYF--SSWGAYGSSKAALNHFAMTLANEER 169
Query: 208 GFARVNTVSPGYIATPISNFVDEDL 232
+ V+PG + T + + E++
Sbjct: 170 QVKAI-AVAPGIVDTDMQVNIRENV 193
>CE26900 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 305
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/188 (23%), Positives = 90/188 (47%), Gaps = 9/188 (4%)
Query: 18 LASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAK 77
L ++L L K ++TGA +G+G +A+ A GA+L +W + ++ E E+
Sbjct: 28 LPYSLLPKKDLYRKKVLITGAGNGLGKLLAQKFAARGATLILWDINLQSVDELKNEIRGN 87
Query: 78 YNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDE 137
+ +Y+ + + K+ + + VI + GK+D+ + NAG+ K +++++E +E
Sbjct: 88 QG-EAHSYEVNLCDPGKIAQVGQQVINDIGKVDILVNNAGIATAK-MILDSSE-----NE 140
Query: 138 WNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIH 197
N+ + +Y + + +G +V AS +G + + A Y++ K +
Sbjct: 141 INRSFDVNVKAHFYTVQQFLPAMLKDNNGHIVTIASAAGKMGS--SGLADYSSTKHAAVG 198
Query: 198 FAKSLAVE 205
F SL E
Sbjct: 199 FHDSLVAE 206
>7294126 [IR] KOG4169 15-hydroxyprostaglandin dehydrogenase and related
dehydrogenases
Length = 278
Score = 57.8 bits (138), Expect = 2e-08
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 19/221 (8%)
Query: 15 PPKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL 74
PP S +GK AVVTG + GIG V++ L AGA+ + L E
Sbjct: 7 PPTTTRISQTKMSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLR 66
Query: 75 SAKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTD 134
+A V+ + V + V+ T E++ + FG ID+ + AG+ + T
Sbjct: 67 AAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGI------FNDKDVQRTL 120
Query: 135 TDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQ-LQACYNAAKA 193
+I++ + + Y K G G G +V+ +MS + P + Y A KA
Sbjct: 121 LVNLGGIINSTLSALPYMGKDNG------GKGGIVV--NMSSVVGLDPMFIIPVYGATKA 172
Query: 194 GVIHFAKSLAVE---WAGFARVNTVSPGYIATPI-SNFVDE 230
G+I+F + LA E + TV PG T + +NF ++
Sbjct: 173 GIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEK 213
>CE26808_2 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 550
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/199 (27%), Positives = 88/199 (44%), Gaps = 13/199 (6%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV---KVVAYQ 86
GKVA+VTG+S+GIG A A AQ GA + + NA +E + K V V+A
Sbjct: 221 GKVALVTGSSNGIGRAAALLFAQQGAKVTI-TGRNAERLEETRQAILKSGVPAENVLAIA 279
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTD--TDEWNKVIHT 144
+ + I +Q+FG++D+ + NAG G D ++++K
Sbjct: 280 ADLATDQGQTDLINGTLQKFGRLDILVNNAGAAVND----PQGRMGIDQQIEDFDKTFQI 335
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAV 204
+ V + + G ++ +S+ G P + Y +KA + F +S A+
Sbjct: 336 NMRSVVTLVQKAKEHLIKT-KGEIINVSSIGGGPHAQPDMM-YYGMSKAALDQFTRSTAI 393
Query: 205 EWAGF-ARVNTVSPGYIAT 222
RVN+VSPG + T
Sbjct: 394 TLIQHGVRVNSVSPGGVYT 412
>7300947 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 361
Score = 57.4 bits (137), Expect = 2e-08
Identities = 48/179 (26%), Positives = 82/179 (44%), Gaps = 10/179 (5%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
+ GKVA+VTG SG+G + LA+ G LAV ++ E LS AY+
Sbjct: 90 VSGKVALVTGGGSGLGREICLELARRGCKLAVVDVNSKGCYETVELLSKIPRCVAKAYKN 149
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAG-VPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
V+ +++ V +E G +D+ + NA +P T P ++ +DE + ++ +
Sbjct: 150 DVSSPRELQLMAAKVEKELGPVDILVNNASLMPMTSTPSLK-------SDEIDTILQLNL 202
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
K + + SG +V +++G +V +P Y A K G+ F +SL E
Sbjct: 203 GSYIMTTKEFLPKMINRKSGHLVAVNALAG-LVPLPG-AGIYTATKYGIEGFMESLRAE 259
>7300731 [Q] KOG1205 Predicted dehydrogenase
Length = 250
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/203 (24%), Positives = 89/203 (43%), Gaps = 16/203 (7%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVT 90
+VAVVTGAS+GIG A L G + L + L A + C V+
Sbjct: 7 RVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSLPADQAARFHTRPCDVS 66
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVY 150
E +V T + + G DV + NAG+ + + E+ D ++ + GV
Sbjct: 67 NEQQVIDTFAWIDRTLGGADVLVNNAGI--IRQMNITDPENSADV---RAILDVNVLGVT 121
Query: 151 YCAK--YVGAQFKRQGSGSMVITASMSGHIVNIPQLQA----CYNAAKAGVIHFAKSLAV 204
+C + ++ Q ++ G +V+ S+ GH ++P ++ Y +K + + L
Sbjct: 122 WCTRQWFLSLQRRKVNDGHVVVINSVVGH--SVPAVEGFSLNMYAPSKHAITALTEILRQ 179
Query: 205 EW---AGFARVNTVSPGYIATPI 224
E+ ++ ++SPG +AT I
Sbjct: 180 EFIKKGTQTKITSISPGVVATEI 202
>Hs7706318 [Q] KOG1205 Predicted dehydrogenase
Length = 339
Score = 57.0 bits (136), Expect = 3e-08
Identities = 57/212 (26%), Positives = 93/212 (42%), Gaps = 16/212 (7%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASL---AVWYNSNAALVERAVELSAKYNVKV 82
+ L V VTGASSGIG +A L++ G SL A + + R +E +
Sbjct: 46 WELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDI 105
Query: 83 VAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVI 142
+ +T+ + + V+QEFG+ID+ + N G+ + T D + K+I
Sbjct: 106 LVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMS------QRSLCMDTSLDVYRKLI 159
Query: 143 HTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSL 202
++ G K V + G +V S+ G I+++P L Y A+K + F L
Sbjct: 160 ELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILG-IISVP-LSIGYCASKHALRGFFNGL 217
Query: 203 AVEWAGFAR--VNTVSPGYIATPISNFVDEDL 232
E A + V+ + PG + SN V+ L
Sbjct: 218 RTELATYPGIIVSNICPGPVQ---SNIVENSL 246
>Hs19923983 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 313
Score = 56.2 bits (134), Expect = 5e-08
Identities = 58/204 (28%), Positives = 91/204 (44%), Gaps = 15/204 (7%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
+ G+V VVTGAS GIG +A L +AGA++ + L A E + + V C
Sbjct: 5 MNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQE-AQSLGGQCVPVVC 63
Query: 88 PVTEEAKVKKTIEDVIQE-FGKIDVFIAN--AGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
++E++V+ E V +E G++DV + N AGV +A T W+ + +
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWE-TPASMWDDINNV 122
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSG--HIVNIPQLQACYNAAKAGVIHFAKSL 202
G Y+C+ Y G G +V+ +S ++ N+P Y KA A
Sbjct: 123 GLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVP-----YGVGKAACDKLAADC 177
Query: 203 AVEWAGFARVNTVS--PGYIATPI 224
A E V+ VS PG + T +
Sbjct: 178 AHELRRHG-VSCVSLWPGIVQTEL 200
>7290386 [I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP reductase
Length = 176
Score = 56.2 bits (134), Expect = 5e-08
Identities = 49/177 (27%), Positives = 87/177 (48%), Gaps = 12/177 (6%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQC 87
L GKVA+VTGA SGIG A LA+ GA + + A E EL ++ + A +
Sbjct: 6 LAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSE---RSAALEV 62
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
V+ V+ ++ + +++F + + N+ G L++ E +++ V +
Sbjct: 63 DVSSAQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPER-----DYDDVYGVNLK 117
Query: 148 GVYYCAK-YVGAQFKRQ-GSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSL 202
G + + Y A +++ +G++V +S+ + N+ QA Y A KAGVI F + L
Sbjct: 118 GTFLVTQAYAKAMIEQKLENGTIVNLSSIVAKMNNVG--QANYAATKAGVISFTERL 172
>Hs20475206 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 305
Score = 55.8 bits (133), Expect = 7e-08
Identities = 44/179 (24%), Positives = 77/179 (42%), Gaps = 9/179 (5%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
S+ G++ ++TGA GIG A+ + L +W + + E A E K V AY
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAE-CRKLGVTAHAYV 91
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
+ ++ +++ V +E G + + + NAG + L T +E K +
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLL------STKDEEITKTFEVNI 145
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
G ++ K + + G +V AS+ GH IP L Y ++K + F + L E
Sbjct: 146 LGHFWITKALLPSMMERNHGHIVTVASVCGH-EGIPYL-IPYCSSKFAAVGFHRGLTSE 202
>Hs7705925 [Q] KOG1207 Diacetyl reductase/L-xylulose reductase
Length = 244
Score = 55.5 bits (132), Expect = 9e-08
Identities = 61/262 (23%), Positives = 104/262 (39%), Gaps = 28/262 (10%)
Query: 23 LDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKV 82
++LF L G+ +VTGA GIG + L GA + + A L
Sbjct: 1 MELF-LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDS------------- 46
Query: 83 VAYQCPVTEEAKVK----KTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEW 138
+ +CP E V + E + G +D+ + NA V + P +E + D
Sbjct: 47 LVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQ-PFLEVTKEAFD---- 101
Query: 139 NKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHF 198
+ + V ++ V +G ++ S + + Y + K +
Sbjct: 102 -RSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTN-HSVYCSTKGALDML 159
Query: 199 AKSLAVEWAGFA-RVNTVSPGYIATPI--SNFVDEDLKNKWHSLIPMGREGLPQELVGAY 255
K +A+E RVN V+P + T + + + D + IP+G+ + +V A
Sbjct: 160 TKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAI 219
Query: 256 LYFASDASTYTTGSDLLVDGAY 277
L+ SD S TTGS L V+G +
Sbjct: 220 LFLLSDRSGMTTGSTLPVEGGF 241
>7300387 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 317
Score = 55.5 bits (132), Expect = 9e-08
Identities = 55/209 (26%), Positives = 90/209 (42%), Gaps = 19/209 (9%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAV-WYNSNAALVERAVELSAKYNVKVVAYQ 86
++GK ++TGA+SGIG A+ LA GA + + N A + + N K++ +
Sbjct: 31 MEGKTVIITGANSGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKETKNNKILVKK 90
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDF 146
+ + V++ D+++ KIDV I NAG + A T D + T+
Sbjct: 91 LDLGSQKSVREFAADIVKTEPKIDVLIHNAG-------MALAFRGQTSEDGVELTMATNH 143
Query: 147 NGVYYCAKYVGAQFKRQGSGSMVITASMSGHI--VNIPQLQA--------CYNAAKAGVI 196
G + + K+ +VI AS + VN+ +L Y +K I
Sbjct: 144 YGPFLLTHLLIDVLKKSAPARIVIVASELYRLSSVNLAKLNPIGTFPAAYLYYVSKFANI 203
Query: 197 HFAKSLAVEWAGF-ARVNTVSPGYIATPI 224
+FA+ LA G VN + PG I + I
Sbjct: 204 YFARELAKRLEGTKVTVNFLHPGMIDSGI 232
>At3g61220 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 296
Score = 55.1 bits (131), Expect = 1e-07
Identities = 48/188 (25%), Positives = 85/188 (44%), Gaps = 17/188 (9%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVK---VVAYQC 87
+ AVVTGA+ GIG+ + LA G + + +E L + + ++ +Q
Sbjct: 7 RYAVVTGANRGIGFEICRQLASEGIRVVLTSRDENRGLEAVETLKKELEISDQSLLFHQL 66
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAE-----SGTDTDEWNKVI 142
V + A + E V +FGK+D+ + NAG+ G ++ AE +G + +W+++I
Sbjct: 67 DVADPASITSLAEFVKTQFGKLDILVNNAGI----GGIITDAEALRAGAGKEGFKWDEII 122
Query: 143 HTDFNGVYYCAKYVGAQFKRQGSGSM-VITASMSGHIVNIP----QLQACYNAAKAGVIH 197
+ C K KR + ++ S S IVN+ QL+ N G++
Sbjct: 123 TETYELTEECIKINYYGPKRMCEAFIPLLKLSDSPRIVNVSSSMGQLKNVLNEWAKGILS 182
Query: 198 FAKSLAVE 205
A++L E
Sbjct: 183 DAENLTEE 190
>At3g12790 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 172
Score = 55.1 bits (131), Expect = 1e-07
Identities = 39/129 (30%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Query: 151 YCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAGF- 209
Y K + G GS++ ++ + + Q+ +AAKA V ++LA+EW
Sbjct: 8 YLKKGAPGRDSSSGGGSIINISATLHYTASWYQIHV--SAAKAAVDATTRNLALEWGTDY 65
Query: 210 -ARVNTVSPGYIA-TP-ISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDASTYT 266
RVN ++PG I TP +S V E+++NK +P+ + G ++ A LY + D+ Y
Sbjct: 66 DIRVNGIAPGPIGGTPGMSKLVPEEIENKTREYMPLYKVGEKWDIAMAALYLSCDSGKYV 125
Query: 267 TGSDLLVDG 275
+G ++VDG
Sbjct: 126 SGLTMVVDG 134
>7295674 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 325
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/209 (23%), Positives = 88/209 (41%), Gaps = 26/209 (12%)
Query: 25 LFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV-KVV 83
L + G+V ++TG G+G +A A+ A + +W + N ++ V+L AK+
Sbjct: 51 LKDISGQVVLITGGGGGVGRLIALNFARLQARIVIW-DINQEAIKTTVDLLAKHGYDNCK 109
Query: 84 AYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
Y +++ ++ + V +E G +D+ I NAG+ K P E + +VI
Sbjct: 110 GYVVDISDREQIYQRASQVTEEVGPVDILINNAGIVCCK-PFWELHD---------RVIQ 159
Query: 144 TDFN----GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQAC--YNAAKAGVIH 197
+N Y+ K R G +V S++G + C Y A K I
Sbjct: 160 NTYNINIISHYWTVKAFLPHMMRNNRGHIVTVGSVTGML----GTYGCSDYAATKYACIG 215
Query: 198 FAKSLAVEWAGFA----RVNTVSPGYIAT 222
F +SL + +++ + P YI T
Sbjct: 216 FHESLLTDLKAHGYDQIQMSLICPYYINT 244
>7290849 [I] KOG1014 17 beta-hydroxysteroid dehydrogenase type 3 HSD17B3
Length = 321
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/211 (26%), Positives = 93/211 (43%), Gaps = 6/211 (2%)
Query: 16 PKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELS 75
PK+ + +DL S G+ AVVTG++ GIG A A+ LA+ G L + S L A E+
Sbjct: 39 PKVFGSSVDL-SKMGEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIG 97
Query: 76 AKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDT 135
KY V+V T ++ I + + V + N G+ + P D
Sbjct: 98 DKYGVEVRVIDVDFTGGDEIYDKIREKTTGL-NVGVLVNNVGISYGH-PEYFLDCYKADP 155
Query: 136 DEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGV 195
++ + + V + Q G ++ +S +G I N L + Y++ KA V
Sbjct: 156 PFLRNIVAANIHSVTHMTALFLPGMISQRRGVIINVSSTAGVIPN--PLLSVYSSTKAFV 213
Query: 196 IHFAKSLAVEWAGFA-RVNTVSPGYIATPIS 225
F+ L E+ + +V PG++AT +S
Sbjct: 214 NKFSDDLQTEYKEHGILIQSVQPGFVATNMS 244
>SPCC162.03 [Q] KOG1205 Predicted dehydrogenase
Length = 292
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 17/173 (9%)
Query: 34 VVTGASSGIGYAVAE-GLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPVTEE 92
++TG+S G+GYA+ + GLAQ N RA + + K++ + VT+
Sbjct: 9 LITGSSKGLGYALVKVGLAQG---------YNVIACSRAPDTITIEHSKLLKLKLDVTDV 59
Query: 93 AKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNGVYYC 152
V+ +D + FG +D+ I NAG LV ES + +E ++ ++ +F GV Y
Sbjct: 60 KSVETAFKDAKRRFGNVDIVINNAGY-----GLVGEFES-YNIEEMHRQMNVNFWGVAYI 113
Query: 153 AKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVE 205
K + G G ++ S P L + YNA+K V ++++ E
Sbjct: 114 TKEALNLMRESGKGGRILQISSVAGYYPSPCL-SMYNASKFAVEGLSQTIMRE 165
>At2g07640 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 156
Score = 53.9 bits (128), Expect = 2e-07
Identities = 38/133 (28%), Positives = 67/133 (49%), Gaps = 6/133 (4%)
Query: 151 YCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAGF- 209
Y K + G GS++ ++ + + Q+ +AAK V ++LA+EW
Sbjct: 8 YLKKVAPGRDSSSGGGSIINISATLHYTASRYQIHV--SAAKVAVDATTRNLALEWGTDY 65
Query: 210 -ARVNTVSPGYIA-TP-ISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFASDASTYT 266
RVN ++ G I TP +S V E+++NK +P+ + G ++ A LY + D+ Y
Sbjct: 66 DIRVNGIATGPIGGTPGMSKLVPEEIENKTREYMPLYKLGEKWDIAMAALYLSCDSGKYM 125
Query: 267 TGSDLLVDGAYCV 279
+G ++VDG C+
Sbjct: 126 SGLTMVVDGGLCL 138
>7301303 [Q] KOG1210 Predicted 3-ketosphinganine reductase
Length = 336
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/187 (27%), Positives = 83/187 (43%), Gaps = 20/187 (10%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVEL--------SAKY 78
S+ G+ VVTG S GIG +A A GA++ V + ++ AV L K+
Sbjct: 32 SIVGRHVVVTGGSKGIGLCLAVECAMKGANVTV-IARDEKMLSGAVALMEVIRQRPDQKF 90
Query: 79 NVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEW 138
+ + + AKV IED FG I I AG+ + +
Sbjct: 91 QYRSLDISGDYDQVAKVLGEIED---SFGPIYTLINCAGMA------ICGVFEEVSVQDV 141
Query: 139 NKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHF 198
+K+++ +F G Y C +YV + K+ G G +VITAS + Y+A K +
Sbjct: 142 HKLMNVNFFGTYNCTRYVLPKMKKAGDGIIVITASQAAMFGIYG--YGPYSATKYALRAM 199
Query: 199 AKSLAVE 205
A+++A+E
Sbjct: 200 AETIAME 206
>CE11498 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 323
Score = 53.5 bits (127), Expect = 3e-07
Identities = 54/213 (25%), Positives = 92/213 (42%), Gaps = 19/213 (8%)
Query: 28 LKGKVAVVTGASSGIGYAVAEGLAQAGASLAVW-----YNSNAALVERAVELSAK----Y 78
L+ +VA+VTGAS GIG +A L +AGA++ + + N L +++ AK
Sbjct: 5 LQDQVALVTGASRGIGRGIALQLGEAGATVYITGRRPELSDNFRLGLPSLDYVAKEITSR 64
Query: 79 NVKVVAYQCPVTEEAKVKKTIEDVIQ-EFGKIDVFIANAGVPWTKG-PLVEAAESGTDTD 136
K +A + +VK E + + E GK+D+ + N K ++ D
Sbjct: 65 GGKGIALYVDHSNMTEVKFLFEKIKEDEEGKLDILVNNVYNSLGKATEMIGKTFFDQDPS 124
Query: 137 EWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSG--HIVNIPQLQACYNAAKAG 194
W+ + YYC+ Y + G +V S+ G ++ N+ Y A K
Sbjct: 125 FWDDINGVGLRNHYYCSVYAARMMVERRKGLIVNVGSLGGLKYVFNV-----AYGAGKEA 179
Query: 195 VIHFAKSLAVEWAGF-ARVNTVSPGYIATPISN 226
+ + +AVE + V T+ PG + T +N
Sbjct: 180 LARMSTDMAVELNPYNVCVVTLIPGPVKTETAN 212
>SPAC977.08 [Q] KOG1205 Predicted dehydrogenase
Length = 236
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 22/201 (10%)
Query: 82 VVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKV 141
V+ Q V + +KK++E I FG+IDV + NAG V + T ++ + +
Sbjct: 16 VLVTQLDVNNFSSIKKSVEKAISHFGRIDVLLNNAGYS------VYSPLESTTEEQIHNI 69
Query: 142 IHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
+T+ G K + F+ Q +G M+I S G + P L Y K + +++
Sbjct: 70 FNTNVFGALEVIKAITPIFRSQHNG-MIINVSSIGGKMTFP-LGCLYYGTKYAIEGISEA 127
Query: 202 LAVEWAGF-ARVNTVSPGYIATPI-------SNFVDED-LKNK-WHSLIPMGREGLPQEL 251
L E +V + PG+ AT ++ + D LK K + L+P + P +
Sbjct: 128 LTWEMQSIGVKVKIIEPGFTATEFRVEEGAGKHYAEYDNLKQKLYEDLLPKLKTATPPQK 187
Query: 252 VGAYLYFA----SDASTYTTG 268
+ + A SD Y TG
Sbjct: 188 IAEVILQAATDESDELRYPTG 208
>SPAC1348.09 [Q] KOG1205 Predicted dehydrogenase
Length = 236
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 22/201 (10%)
Query: 82 VVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKV 141
V+ Q V + +KK++E I FG+IDV + NAG V + T ++ + +
Sbjct: 16 VLVTQLDVNNFSSIKKSVEKAISHFGRIDVLLNNAGYS------VYSPLESTTEEQIHNI 69
Query: 142 IHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKS 201
+T+ G K + F+ Q +G M+I S G + P L Y K + +++
Sbjct: 70 FNTNVFGALEVIKAITPIFRSQHNG-MIINVSSIGGKMTFP-LGCLYYGTKYAIEGISEA 127
Query: 202 LAVEWAGF-ARVNTVSPGYIATPI-------SNFVDED-LKNK-WHSLIPMGREGLPQEL 251
L E +V + PG+ AT ++ + D LK K + L+P + P +
Sbjct: 128 LTWEMQSIGVKVKIIEPGFTATEFRVEEGAGKHYAEYDNLKQKLYEDLLPKLKTATPPQK 187
Query: 252 VGAYLYFA----SDASTYTTG 268
+ + A SD Y TG
Sbjct: 188 IAEVILQAATDESDELRYPTG 208
>Hs19923850 [I] KOG1014 17 beta-hydroxysteroid dehydrogenase type 3 HSD17B3
Length = 309
Score = 52.8 bits (125), Expect = 6e-07
Identities = 56/219 (25%), Positives = 104/219 (46%), Gaps = 16/219 (7%)
Query: 16 PKLASNVLDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELS 75
P+L S DL G+ AVV+GA+ GIG A AE LA G ++ + + L A +++
Sbjct: 33 PRLGSRA-DLIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIA 91
Query: 76 AKYNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDT 135
Y V+ + ++ I + +++ + + + N GV + P + ++
Sbjct: 92 DTYKVETDIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFY---PYPQYFTQLSED 147
Query: 136 DEWNKVIHTDFNGVYYCAKYV--GAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKA 193
W+ +I+ + V G +++G+ ++T S PQL A ++A+KA
Sbjct: 148 KLWD-IINVNIAAASLMVHVVLPGMVERKKGA---IVTISSGSCCKPTPQL-AAFSASKA 202
Query: 194 GVIHFAKSLAVEWAGFA-RVNTVSPGYIA---TPISNFV 228
+ HF+++L E+A V ++ P Y+A T SNF+
Sbjct: 203 YLDHFSRALQYEYASKGIFVQSLIPFYVAASMTAPSNFL 241
>7296047 [Q] KOG1205 Predicted dehydrogenase
Length = 321
Score = 52.8 bits (125), Expect = 6e-07
Identities = 58/211 (27%), Positives = 93/211 (43%), Gaps = 24/211 (11%)
Query: 23 LDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAK----- 77
+ L S++G+V +TGASSGIG A+A LA+ G L + L + E A
Sbjct: 39 VSLSSMRGQVVWITGASSGIGRALALSLARHGVKLVLSARRLEQLEQVQEECLAAARGLL 98
Query: 78 YNVKVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAG----VPWTKGPLVEAAESGT 133
V+ Q + + + K + V+ F ++DV + NAG WT+
Sbjct: 99 ATKDVLVIQMDMLDLDEHKTHLNTVLNHFHRLDVLVNNAGRSQRASWTE----------V 148
Query: 134 DTDEWNKVIHTDFNGVYYCAKYVGAQFKRQ--GSGSMVITASMSGHIVNIPQLQACYNAA 191
+ + ++ D V + ++ V F Q G G + T+S++G +P Y AA
Sbjct: 149 EIEVDRELFELDVFAVVHLSRLVVRYFVEQNGGRGHIAATSSIAG-FSPVP-FSPTYCAA 206
Query: 192 KAGVIHFAKSLAVEWAGFARVNTVSPGYIAT 222
K + + SL VE V+ +PG IAT
Sbjct: 207 KHALNAYLLSLKVEMRKL-DVSLFAPGPIAT 236
>CE13008 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 247
Score = 52.4 bits (124), Expect = 7e-07
Identities = 61/255 (23%), Positives = 107/255 (41%), Gaps = 39/255 (15%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKY-----NVKVVA 84
GK +VTG+SSGIG A A A+ GA + + +A +E + K NV VV
Sbjct: 6 GKSVIVTGSSSGIGRATAVLFAKYGAQVTI-TGRDAGKLEATKKKMLKVMKNPENVCVVV 64
Query: 85 YQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHT 144
+T+ + ++ + FG+IDV + NAG G + T+ ++K
Sbjct: 65 --ANLTDSDGQDEIVQSALDAFGRIDVLVNNAGANVVDGTF----NTDQSTELYHKTFQI 118
Query: 145 DFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQA---CYNAAKAGVIHFAKS 201
+F V K + G +V +S++ PQ A Y A+KA + + +
Sbjct: 119 NFEAVIEMVKKT-KNHLIESKGEIVNVSSVAAG----PQALAPSPYYAASKAALDQYTRC 173
Query: 202 LAVEWAGFARVNTVSPGYIATPISNFVDEDLKNKWHSLIPMGREGLPQELVGAYLYFAS- 260
+A++ I ++E+ + + IP G G P+++ ++ A
Sbjct: 174 VALDL-----------------ILQGIEENFTSN-RACIPAGVCGKPEDIAELIIFLADR 215
Query: 261 DASTYTTGSDLLVDG 275
S+Y G ++ DG
Sbjct: 216 KRSSYIIGQSIVADG 230
>CE02490_1 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 302
Score = 52.0 bits (123), Expect = 9e-07
Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 6/93 (6%)
Query: 30 GKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAA------LVERAVELSAKYNVKVV 83
G+ ++TGAS GIG +A LA+ GA++ V + A + A E K K +
Sbjct: 9 GRTVLITGASRGIGKEIALKLAKDGANIVVAAKTATAHPKLPGTIYSAAEEIEKAGGKAL 68
Query: 84 AYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANA 116
V +EA VK ++E+ +++FG ID+ I NA
Sbjct: 69 PCIVDVRDEASVKASVEEAVKKFGGIDILINNA 101
>At5g61830 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 316
Score = 51.6 bits (122), Expect = 1e-06
Identities = 43/145 (29%), Positives = 70/145 (47%), Gaps = 12/145 (8%)
Query: 32 VAVVTGASSGIGYAVAEGLAQAGASLAVW-YNSNAALVERAVELSAKYNVKVVAYQCPVT 90
VAVVTG++ GIG+ +A LA G ++ + N NA L + +KV +Q VT
Sbjct: 38 VAVVTGSNRGIGFEIARQLAVHGLTVVLTARNVNAGLEAVKSLRHQEEGLKVYFHQLDVT 97
Query: 91 EEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGP--LVEAAESGTDTDEWNKVIHTDFNG 148
+ + +++ + Q FG +D+ + NAGV + G VE AE+ VI T++ G
Sbjct: 98 DSSSIREFGCWLKQTFGGLDILVNNAGVNYNLGSDNTVEFAET---------VISTNYQG 148
Query: 149 VYYCAKYVGAQFKRQGSGSMVITAS 173
K + + G+ V+ S
Sbjct: 149 TKNMTKAMIPLMRPSPHGARVVNVS 173
>SPAC23D3.11 [Q] KOG1209 1-Acyl dihydroxyacetone phosphate reductase and related
dehydrogenases
Length = 296
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/200 (27%), Positives = 96/200 (47%), Gaps = 21/200 (10%)
Query: 31 KVAVVTGASSG-IGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCPV 89
K ++TG S G IG A+A Q G + + A VER L+ + + V
Sbjct: 5 KFVLITGCSEGGIGNALALKFHQEGFQVL----ATARQVERMDNLT---KAGLQTLKLDV 57
Query: 90 TEEAKVKKTIEDVIQEF--GKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFN 147
T+E V++ +E +++F G + I NAG P + P ++ D ++ +KV+ +F
Sbjct: 58 TDEDSVRE-VEQEVRKFTNGSLHYLINNAGAPCS-APAIDL-----DIEDVSKVMDVNFY 110
Query: 148 GVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWA 207
GV K Q R G++V S+ ++ A YNA+KA ++ ++ +L +E A
Sbjct: 111 GVIRMNKAFQHQLIR-AKGTIVNVNSLVSYVPFA--FNAAYNASKAALLAYSNTLRIELA 167
Query: 208 GF-ARVNTVSPGYIATPISN 226
F +V ++ G + T I +
Sbjct: 168 PFGVQVTSIMTGGVQTKIQS 187
>CE21514 [R] KOG0725 Reductases with broad range of substrate specificities
Length = 319
Score = 50.8 bits (120), Expect = 2e-06
Identities = 59/227 (25%), Positives = 96/227 (41%), Gaps = 29/227 (12%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVW-------YNSNAAL--VERAVELSAK 77
SL G++A+VTGAS GIG +A L +AGA++ + NS L +E + K
Sbjct: 2 SLAGQIAIVTGASRGIGRGIALQLGEAGATVYITGRKPEESLNSKVGLSGLEATADEITK 61
Query: 78 YNVKVVAYQCPVTEEAKVKKTIEDVIQEF-GKIDVFIANAGVPWTKGPLVEAAESG---- 132
K +A +VK E V +E G++D+ + NA +G + G
Sbjct: 62 RGGKGIARFVDHQNMEEVKNFFEVVEKEHQGQLDILVNNA----YQGVTAISENMGKPFY 117
Query: 133 -TDTDEWNKVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSG--HIVNIPQLQACYN 189
TD W+ + + Y+C Y + G +V +S G ++ N+ Y
Sbjct: 118 ETDPYVWDTINNVGLRNHYFCTVYAARLMTARNKGLIVNVSSGGGLRYLFNV-----AYG 172
Query: 190 AAKAGVIHFAKSLAVEW-AGFARVNTVSPGYIATPISN--FVDEDLK 233
K + + AVE V ++ PG + T + + F DE+ K
Sbjct: 173 VGKQALDRMSADTAVELRKKNVCVVSIWPGAVRTELVDKMFKDENGK 219
>7300831 [Q] KOG1205 Predicted dehydrogenase
Length = 248
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/207 (28%), Positives = 93/207 (44%), Gaps = 22/207 (10%)
Query: 26 FSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAY 85
F + KVAVVTGAS GIG A LA AG + V L+E A+ K+ A
Sbjct: 5 FYWRNKVAVVTGASVGIGATTAIELANAG-MVVVGLARRVELIE-ALRDQVTGVGKIFAR 62
Query: 86 QCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTD 145
QC + +E ++ + ++F I V I NAG+ L S + T + ++ T+
Sbjct: 63 QCDLNDEEQLASAFNWIREKFQAIHVLICNAGI------LKANFLSESPTKDIKELFDTN 116
Query: 146 FNGVYYC----AKYVGAQFKRQGSGSMVITASMSGH-IVNIP-QLQACYNAAKAGVIHFA 199
C K++ A R G +V+ S+ GH I +P L + Y A K +
Sbjct: 117 VVATASCLREALKHMAAVKVR---GHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALC 173
Query: 200 KSLAVEWAGFARVN----TVSPGYIAT 222
+++ E F ++N ++ PG + T
Sbjct: 174 QTVRQE-IHFLKLNIKLTSICPGMVDT 199
>YDL114w [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 308
Score = 49.7 bits (117), Expect = 5e-06
Identities = 51/215 (23%), Positives = 92/215 (42%), Gaps = 24/215 (11%)
Query: 29 KGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQCP 88
K A++TG SSG+G+ +A+ L++ + V A + +YN + YQC
Sbjct: 37 KNATALITGGSSGLGFELAKELSRRINKVIV-----ADIQSFPTFAQVEYN-NIFYYQCD 90
Query: 89 VTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIHTDFNG 148
+T ++K + + ++ G I++ I NAGV ++ E T+ E ++I + G
Sbjct: 91 ITSLDEIKNLKKAIERDHGNINIIINNAGVAH-----IKKLEHMTN-KEVEQLIDINLIG 144
Query: 149 VYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLAVEWAG 208
Y G ++ AS+ G + P Y A+K +I F K ++ +
Sbjct: 145 AYRIISTFAEDMIDNREGFIINIASVLGELT--PARLTSYGASKGAMIGFHKCMSRHFRS 202
Query: 209 FA--------RVNTVSPGYIATPISNFVDEDLKNK 235
+ + V PG I T + F+D +K
Sbjct: 203 LSTECNKTGIKTLLVCPGKIKT--NMFIDVPTPSK 235
>At2g24190 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 296
Score = 49.7 bits (117), Expect = 5e-06
Identities = 46/182 (25%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 31 KVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVK---VVAYQC 87
+ A+VTG + GIG+ + LA G + + +E L + + +V +Q
Sbjct: 7 RYAIVTGGNRGIGFEICRQLANKGIRVILTSRDEKQGLEAVETLKKELEISDQSIVFHQL 66
Query: 88 PVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTD--EWNKVIHTD 145
V++ V E V FGK+D+ I NAGV V+A +GT + +W + I
Sbjct: 67 DVSDPVSVTSLAEFVKTHFGKLDILINNAGVGGVITD-VDALRAGTGKEGFKWEETITET 125
Query: 146 FNGVYYCAKYVGAQFKRQGSGSM-VITASMSGHIVNIP----QLQACYNAAKAGVIHFAK 200
+ C K KR + ++ S S I+N+ Q++ N G++ A+
Sbjct: 126 YELAEECIKINYYGPKRMCEAFIPLLQLSDSPRIINVSSFMGQVKNLVNEWAKGILSDAE 185
Query: 201 SL 202
+L
Sbjct: 186 NL 187
>Hs20373187 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 231
Score = 49.3 bits (116), Expect = 6e-06
Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 14/182 (7%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVW---YNSNAALVERAVELSAKYNVKVV 83
++ G++ ++TGA SG+G +A A+ G+ L +W N + A E A +V
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGA---TRVH 93
Query: 84 AYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWNKVIH 143
AY C +++ V + + V +E G + + I NAG+ K L + K
Sbjct: 94 AYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFL------DCPDELMEKSFD 147
Query: 144 TDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFAKSLA 203
+F + K G +V +S +G + + L A Y A+K FA+S+
Sbjct: 148 VNFKAHLWTYKAFLPAMIANDHGHLVCISSSAG-LSGVNGL-ADYCASKFAAFGFAESVF 205
Query: 204 VE 205
VE
Sbjct: 206 VE 207
>CE07544 [Q] KOG1205 Predicted dehydrogenase
Length = 262
Score = 49.3 bits (116), Expect = 6e-06
Identities = 52/203 (25%), Positives = 92/203 (44%), Gaps = 20/203 (9%)
Query: 23 LDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV-- 80
L +K KV V+TGASSG+G ++A L + GA + + S L E EL + +
Sbjct: 40 LPKLDVKNKVVVITGASSGLGKSLAFELYKRGAQVILLARSTEKLKEICEELKETFPLNQ 99
Query: 81 -KVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWN 139
+ + Y +T+ + E ++D+ I NAG+ +G + T +
Sbjct: 100 NEPIYYYFDITDSEQAPWA------EIPRVDILINNAGMS-NRGSCQD-----TTMEIHR 147
Query: 140 KVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
+ + T++ G + + + + K G +V+T+S+ G + IP + Y A+K + +
Sbjct: 148 QAMETNYFGHVHVTQALLS--KLSPDGCIVVTSSIQGKVA-IP-YRGSYGASKHALQGYF 203
Query: 200 KSLAVEWAGFARVNTVSPGYIAT 222
L E + VS GYI T
Sbjct: 204 DCLRAEHKNL-HILVVSAGYINT 225
>CE07539 [Q] KOG1205 Predicted dehydrogenase
Length = 537
Score = 49.3 bits (116), Expect = 6e-06
Identities = 59/215 (27%), Positives = 95/215 (43%), Gaps = 21/215 (9%)
Query: 23 LDLFSLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNV-- 80
L ++K K+ V+TGASSG+G ++A L + GA + + S L E EL+ + +
Sbjct: 71 LSKLNVKNKIVVITGASSGLGKSLAFELYKRGAQVILLARSTEKLKEICAELTKTFPLNK 130
Query: 81 -KVVAYQCPVTEEAKVKKTIEDVIQEFGKIDVFIANAGVPWTKGPLVEAAESGTDTDEWN 139
K Y +T K + K+DV I NAG+ +G + T
Sbjct: 131 NKPTYYFFDITNPDKAPWA------QIPKVDVLINNAGMS-NRGSCQD-----TTMAIHR 178
Query: 140 KVIHTDFNGVYYCAKYVGAQFKRQGSGSMVITASMSGHIVNIPQLQACYNAAKAGVIHFA 199
K + T+ G + + + K G +V+T+S+ G + IP + Y+A+K + +
Sbjct: 179 KAMETNLFGHVQVTQSLLS--KLSPDGCIVVTSSIQGKVA-IP-YRGSYSASKHALQGYF 234
Query: 200 KSLAVEWAGFARVNTVSPGYIATPI-SNFVDEDLK 233
L E + VS GYI T S +D D K
Sbjct: 235 DCLRAEHKNL-HILVVSAGYINTGFGSRALDTDGK 268
>CE28011 [Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11
Length = 427
Score = 48.9 bits (115), Expect = 8e-06
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 27 SLKGKVAVVTGASSGIGYAVAEGLAQAGASLAVWYNSNAALVERAVELSAKYNVKVVAYQ 86
S++G+ ++TG SG+G A+A A+ A +A+ + +E ++A+ N+ Y
Sbjct: 38 SVQGQTVIITGGGSGLGRAMALDFAKRKAKVAIIDVNKEGGLETVKTIAAEGNMAKFWY- 96
Query: 87 CPVTEEAKVKKTIEDVIQEFGKIDVFIANAGV 118
C +++ +KKT +++ FG +++ I NA +
Sbjct: 97 CDISDVDNMKKTAKEIEDTFGDVNIVICNAAI 128
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,269,640
Number of Sequences: 60738
Number of extensions: 655215
Number of successful extensions: 2368
Number of sequences better than 1.0e-05: 162
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 145
Number of HSP's that attempted gapping in prelim test: 2069
Number of HSP's gapped (non-prelim): 171
length of query: 280
length of database: 30,389,216
effective HSP length: 105
effective length of query: 175
effective length of database: 24,011,726
effective search space: 4202052050
effective search space used: 4202052050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)