ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV6244 check: MH Q KOG0405 Secondary metabolites biosynthesis, transport and catabolism Pyridine nucleotide-disulphide oxidoreductase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV6244 2145151 2143700 -484
(484 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL091w [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 705 0.0
SPBC17A3.07 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoredu... 471 e-133
Hs10835189 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreduc... 396 e-110
CE17558 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 394 e-109
At3g54660 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 281 1e-75
At3g24170 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 263 3e-70
CE26906 [O] KOG4716 Thioredoxin reductase 258 1e-68
7290913 [O] KOG4716 Thioredoxin reductase 256 5e-68
CE15373 [O] KOG4716 Thioredoxin reductase 248 1e-65
HsM5454136 [O] KOG4716 Thioredoxin reductase 238 1e-62
Hs22035672 [O] KOG4716 Thioredoxin reductase 238 1e-62
Hs22035670 [O] KOG4716 Thioredoxin reductase 238 1e-62
Hs4507747 [O] KOG4716 Thioredoxin reductase 235 1e-61
Hs20536269 [O] KOG4716 Thioredoxin reductase 227 3e-59
7296552 [O] KOG4716 Thioredoxin reductase 223 5e-58
Hs22035668 [O] KOG4716 Thioredoxin reductase 213 7e-55
At1g48030 [C] KOG1335 Dihydrolipoamide dehydrogenase 169 1e-41
At3g17240 [C] KOG1335 Dihydrolipoamide dehydrogenase 161 2e-39
YFL018c [C] KOG1335 Dihydrolipoamide dehydrogenase 155 2e-37
Hs4557525 [C] KOG1335 Dihydrolipoamide dehydrogenase 153 5e-37
At3g16950 [C] KOG1335 Dihydrolipoamide dehydrogenase 152 8e-37
7293932 [C] KOG1335 Dihydrolipoamide dehydrogenase 151 2e-36
SPAC1002.09c [C] KOG1335 Dihydrolipoamide dehydrogenase 136 8e-32
CE16262 [C] KOG1335 Dihydrolipoamide dehydrogenase 115 2e-25
YPL017c [C] KOG1335 Dihydrolipoamide dehydrogenase 112 1e-24
CE27373 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase 61 4e-09
At1g63940 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase 55 3e-07
At3g09940 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase 50 8e-06
>YPL091w [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 483
Score = 705 bits (1820), Expect = 0.0
Identities = 333/462 (72%), Positives = 394/462 (85%), Gaps = 2/462 (0%)
Query: 22 HYDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKAMGGTCVNKGCVPKKVMWYASDLATRI 81
HYDYLVI KTLL+EAKA+GGTCVN GCVPKKVMWYASDLATR+
Sbjct: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV 82
Query: 82 GHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFT 141
HA+ Y L+++LPL KE+LTFNWPEFK+KRDAY+HRLNGIY++NL KE VD V+GWA F
Sbjct: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142
Query: 142 VDGKVQVKKADNCTETYTADHILVATGGKPIYPAKIPGYDYGVSSDEFFELEDQPKKVVV 201
DG V+V+K DN TE Y+A+HILVATGGK I+P IPG++ G SD FF LE+QPKKVVV
Sbjct: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVV 202
Query: 202 VGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVT 261
VGAGYIG+E+AGVF+GLGS++HLVIRGETVLRKFD+CIQ T+TD Y+KEG+N+HK S +
Sbjct: 203 VGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIV 262
Query: 262 KVEKDESTGKLNIQLDTGKNIDNVDSLIWTIGRRSLLGLGLENIGVKLDAKEQIVVDEYQ 321
KVEK+ T KL I ++ K+ID+VD LIWTIGR+S LG+G EN+G+KL++ +QI+ DEYQ
Sbjct: 263 KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQ 322
Query: 322 NSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEA 381
N++V N+YSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKF+N K DYENVPSV+FSHPEA
Sbjct: 323 NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEA 382
Query: 382 GSIGLSEREAIEKFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHI 441
GSIG+SE+EAIEK+GK+N+KVYNSKF AMYYAM+ E K+PTRYK+VC G EKVVGLHI
Sbjct: 383 GSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSE--KSPTRYKIVCAGPNEKVVGLHI 440
Query: 442 IGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSAEELVTL 483
+GDSSAEILQGFGVAIKMGATKADFD+CVAIHPTSAEELVT+
Sbjct: 441 VGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482
>SPBC17A3.07 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 464
Score = 471 bits (1213), Expect = e-133
Identities = 256/465 (55%), Positives = 321/465 (68%), Gaps = 13/465 (2%)
Query: 23 YDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKA-MGGTCVNKGCVPKKVMWYASDLATRI 81
+DYLVI K LIEA +GGTCVN GCVPKK+MW +DL ++
Sbjct: 8 FDYLVIGGGSGGLASARRAAKHGAKVALIEASGRLGGTCVNYGCVPKKIMWNIADLVAKM 67
Query: 82 GHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFT 141
A N F + L +F+W K+KRDAYI RLNGIYERN+ K+GV Y+ G ASF
Sbjct: 68 KTAKQ-NGFPNSQLG----SFDWGMIKRKRDAYIGRLNGIYERNVNKDGVAYISGHASFV 122
Query: 142 VDGKVQVKKADNC-TETYTADHILVATGGKPIYPAKIPGYDYGVSSDEFFELEDQPKKVV 200
+V V D T+ ++A +IL+A GG PI+P+ IPG +YG+ SD FFELE QPK+V
Sbjct: 123 SPTEVAVDMNDGSGTQVFSAKYILIAVGGHPIWPSHIPGAEYGIDSDGFFELESQPKRVA 182
Query: 201 VVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSS-N 259
+VGAGYI VE+AGVF LG+++H+ IR LRKFD I + + D + G+N+H +S
Sbjct: 183 IVGAGYIAVELAGVFAALGTETHMFIRQSKFLRKFDPIISDGIMDHFQHIGINVHTNSLE 242
Query: 260 VTKVEKDESTGKLNIQLDTGKNIDNVDSLIWTIGRR-SLLGLGLENIGVKLDAKEQIVVD 318
KVEK S G+L I G NVD+L+W IGR + GL LE GVK I+ D
Sbjct: 243 FKKVEKLPS-GELCIHQQDGSTF-NVDTLLWAIGRAPKIQGLRLEKAGVKTLPNGIIIAD 300
Query: 319 EYQNSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSH 378
YQ ++V V SLGDV GK+ELTPVAIAAGR+LS+RLFG K+ DYE VPSVVF+H
Sbjct: 301 TYQRTNVPTVLSLGDVCGKLELTPVAIAAGRRLSDRLFGG--IKDAHLDYEEVPSVVFAH 358
Query: 379 PEAGSIGLSEREAIEKFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVG 438
PEAG+IGL+E+EAI+K+G+ +KVYN+KFN + Y+M+E++DK PT YKLVC G +KVVG
Sbjct: 359 PEAGTIGLTEQEAIDKYGESQIKVYNTKFNGLNYSMVEQEDKVPTTYKLVCAGPLQKVVG 418
Query: 439 LHIIGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSAEELVTL 483
LH++GD SAEILQGFGVAIKMGATK+DFDSCVAIHPTSAEELVTL
Sbjct: 419 LHLVGDFSAEILQGFGVAIKMGATKSDFDSCVAIHPTSAEELVTL 463
>Hs10835189 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 479
Score = 396 bits (1017), Expect = e-110
Identities = 220/470 (46%), Positives = 300/470 (63%), Gaps = 22/470 (4%)
Query: 23 YDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKAMGGTCVNKGCVPKKVMWYASDLATRIG 82
YDYLVI + ++E+ +GGTCVN GCVPKKVMW + + +
Sbjct: 22 YDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTA-VHSEFM 80
Query: 83 HAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTV 142
H H+ D FNW K+KRDAY+ RLN IY+ NLTK ++ + G A+FT
Sbjct: 81 HDHA-----DYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTS 135
Query: 143 DGKVQVKKADNCTETYTADHILVATGGKPIYP--AKIPGYDYGVSSDEFFELEDQPKKVV 200
D K ++ + + YTA HIL+ATGG P P ++IPG G++SD FF+LE+ P + V
Sbjct: 136 DPKPTIEVSG---KKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSV 192
Query: 201 VVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNV 260
+VGAGYI VE+AG+ + LGS + L+IR + VLR FD I T+ GV + K S V
Sbjct: 193 IVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQV 252
Query: 261 TKVEKDESTGKLNI------QLDTGKNIDNVDSLIWTIGR-RSLLGLGLENIGVKLDAKE 313
+V+K S ++++ +L I +VD L+W IGR + L L +G++ D K
Sbjct: 253 KEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKG 312
Query: 314 QIVVDEYQNSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPS 373
I+VDE+QN++VK +Y++GDV GK LTPVAIAAGRKL++RLF E ++ K DY N+P+
Sbjct: 313 HIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLF--EYKEDSKLDYNNIPT 370
Query: 374 VVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEE 433
VVFSHP G++GL+E EAI K+G +NVK Y++ F MY+A+ K KT K+VC +E
Sbjct: 371 VVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVT--KRKTKCVMKMVCANKE 428
Query: 434 EKVVGLHIIGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSAEELVTL 483
EKVVG+H+ G E+LQGF VA+KMGATKADFD+ VAIHPTS+EELVTL
Sbjct: 429 EKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTL 478
>CE17558 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 473
Score = 394 bits (1011), Expect = e-109
Identities = 228/464 (49%), Positives = 291/464 (62%), Gaps = 21/464 (4%)
Query: 23 YDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKAMGGTCVNKGCVPKKVMWYASDLATRIG 82
+DYLVI LIE+ +GGTCVN GCVPKKVM+ S A I
Sbjct: 21 FDYLVIGGGSGGIASARRAREFGVSVGLIESGRLGGTCVNVGCVPKKVMYNCSLHAEFIR 80
Query: 83 HAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTV 142
Y D+ L K F+W KK RD YI RLNG+YE L V+Y+ G A+F
Sbjct: 81 DHADYGF--DVTLNK----FDWKVIKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAE 134
Query: 143 DGKVQVKKADNCTETYTADHILVATGGKPIYPAKIPGYDYGVSSDEFFELEDQPKKVVVV 202
DG V+V A Y + L+A GGKP P I G ++G+ SD FF+LED P + VVV
Sbjct: 135 DGTVEVNGAK-----YRGKNTLIAVGGKPTIP-NIKGAEHGIDSDGFFDLEDLPSRTVVV 188
Query: 203 GAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEG--VNIHKSSNV 260
GAGYI VEIAGV LGSD+HL+IR + VLR FD + + +T +E +++HK++ V
Sbjct: 189 GAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQV 248
Query: 261 TKVEKDESTGKLNIQLDTGKNIDNVDSLIWTIGRRSLLG-LGLENIGVKLDAKEQIVVDE 319
T+V K + G L I+ TG I+ V +LIW IGR L L LE +GVK D I+VDE
Sbjct: 249 TEVIKGDD-GLLTIKTTTGV-IEKVQTLIWAIGRDPLTKELNLERVGVKTDKSGHIIVDE 306
Query: 320 YQNSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHP 379
YQN+S + S+GD GK LTPVAIAAGR+LS+RLF E + K YEN+ +VVFSHP
Sbjct: 307 YQNTSAPGILSVGDDTGKFLLTPVAIAAGRRLSHRLFNGET--DNKLTYENIATVVFSHP 364
Query: 380 EAGSIGLSEREAIEKFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGL 439
G++GL+E EA+EK+GKD V +Y S+FN M +A+ + K+K KLVC G++EKVVG+
Sbjct: 365 LIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVTKHKEKAAM--KLVCVGKDEKVVGV 422
Query: 440 HIIGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSAEELVTL 483
H+ G S E+LQGF VA+ MGATK FD VAIHPTSAEELVT+
Sbjct: 423 HVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELVTM 466
>At3g54660 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 565
Score = 281 bits (720), Expect = 1e-75
Identities = 165/440 (37%), Positives = 247/440 (55%), Gaps = 37/440 (8%)
Query: 53 AKAMGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNL-FEDLPLTKENLTFNWPEFKKKR 111
A +GGTCV +GCVPKK++ YAS + +H + +E P + +W +
Sbjct: 128 AGGVGGTCVLRGCVPKKLLVYASKYSHEFEDSHGFGWKYETEP------SHDWTTLIANK 181
Query: 112 DAYIHRLNGIYERNLTKEGVDYVYGWA------SFTVDGKVQVKKADNCTETYTADHILV 165
+A + RL GIY+ L+K V + G + VDGK+ YT +IL+
Sbjct: 182 NAELQRLTGIYKNILSKANVKLIEGRGKVIDPHTVDVDGKI-----------YTTRNILI 230
Query: 166 ATGGKPIYPAKIPGYDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLV 225
A GG+P P IPG ++ + SD +L +PKK+ +VG GYI +E AG+FNGL + H+
Sbjct: 231 AVGGRPFIP-DIPGKEFAIDSDAALDLPSKPKKIAIVGGGYIALEFAGIFNGLNCEVHVF 289
Query: 226 IRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDTGKN-IDN 284
IR + VLR FD+ +++ V + G+ H + + K G + L T K ++
Sbjct: 290 IRQKKVLRGFDEDVRDFVGEQMSLRGIEFHTEESPEAIIK---AGDGSFSLKTSKGTVEG 346
Query: 285 VDSLIWTIGRR-SLLGLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVVGKVELTPV 343
+++ GR+ + LGLEN+GVK+ I VDEY +SV +++++GDV ++ LTPV
Sbjct: 347 FSHVMFATGRKPNTKNLGLENVGVKMAKNGAIEVDEYSQTSVPSIWAVGDVTDRINLTPV 406
Query: 344 AIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVY 403
A+ G L+ LF E K DY VP VFS P G++GL+E +AIE++G +V VY
Sbjct: 407 ALMEGGALAKTLFQNEP---TKPDYRAVPCAVFSQPPIGTVGLTEEQAIEQYG--DVDVY 461
Query: 404 NSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATK 463
S F + + D+ KL+ KV+G+H+ G+ S EI+QGFGVA+K G TK
Sbjct: 462 TSNFRPLKATLSGLPDRV--FMKLIVCANTNKVLGVHMCGEDSPEIIQGFGVAVKAGLTK 519
Query: 464 ADFDSCVAIHPTSAEELVTL 483
ADFD+ V +HPT+AEE VT+
Sbjct: 520 ADFDATVGVHPTAAEEFVTM 539
>At3g24170 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 499
Score = 263 bits (673), Expect = 3e-70
Identities = 156/433 (36%), Positives = 238/433 (54%), Gaps = 16/433 (3%)
Query: 52 EAKAMGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKR 111
E +GGTCV +GCVPKK++ Y + + A +Y E + F W + +K+
Sbjct: 65 EIGGVGGTCVIRGCVPKKILVYGATYGGELEDAKNYGWE-----INEKVDFTWKKLLQKK 119
Query: 112 DAYIHRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKP 171
I RLN IY+R L V G +V+V++ D +YTA HIL+ATG +
Sbjct: 120 TDEILRLNNIYKRLLANAAVKLYEGEGRVVGPNEVEVRQIDGTKISYTAKHILIATGSRA 179
Query: 172 IYPAKIPGYDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETV 231
P IPG++ ++SDE LE+ PK+ +V+G GYI VE A ++ G+G+ L R E
Sbjct: 180 QKP-NIPGHELAITSDEALSLEEFPKRAIVLGGGYIAVEFASIWRGMGATVDLFFRKELP 238
Query: 232 LRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDTGKNIDNVDSLIWT 291
LR FDD ++ V GVN+H +++T++ K + K+ + + D +++
Sbjct: 239 LRGFDDEMRALVARNLEGRGVNLHPQTSLTQLTKTDQGIKV---ISSHGEEFVADVVLFA 295
Query: 292 IGRR-SLLGLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVVGKVELTPVAIAAGRK 350
GR + L LE +GV+LD + VDEY +++ +++++GD ++ LTPVA+
Sbjct: 296 TGRSPNTKRLNLEAVGVELDQAGAVKVDEYSRTNIPSIWAVGDATNRINLTPVALMEATC 355
Query: 351 LSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKFNAM 410
+N FG K K +Y NV VF P +GLSE EA+E+ D + V+ S FN M
Sbjct: 356 FANTAFGG---KPTKAEYSNVACAVFCIPPLAVVGLSEEEAVEQATGD-ILVFTSGFNPM 411
Query: 411 YYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATKADFDSCV 470
+ ++K T KL+ + +KV+G + G +AEI+QG +A+K GATKA FDS V
Sbjct: 412 KNTISGRQEK--TLMKLIVDEKSDKVIGASMCGPDAAEIMQGIAIALKCGATKAQFDSTV 469
Query: 471 AIHPTSAEELVTL 483
IHP+SAEE VT+
Sbjct: 470 GIHPSSAEEFVTM 482
>CE26906 [O] KOG4716 Thioredoxin reductase
Length = 665
Score = 258 bits (660), Expect = 1e-68
Identities = 160/446 (35%), Positives = 247/446 (54%), Gaps = 27/446 (6%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M AS L I A Y L + + W + +I
Sbjct: 215 LGGTCVNVGCIPKKLMHQASLLGHSIHDAKKYGW----KLPEGKVEHQWNHLRDSVQDHI 270
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYPA 175
LN Y L ++ V Y+ + FT ++ E TAD L++TG +P YP
Sbjct: 271 ASLNWGYRVQLREKTVTYINSYGEFTGPFEISATNKKKKVEKLTADRFLISTGLRPKYP- 329
Query: 176 KIPGY-DYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRK 234
+IPG +Y ++SD+ F+L P K + VGA Y+ +E AG +G G D +++R +LR
Sbjct: 330 EIPGVKEYTITSDDLFQLPYSPGKTLCVGASYVSLECAGFLHGFGFDVTVMVR-SILLRG 388
Query: 235 FDDCIQETVTDTYIKEGVNIHKSSNVTKVEK-----DESTGKLNI-----QLDTGKN--- 281
FD + E + I G+ ++ T++E+ DE GK + +TG+
Sbjct: 389 FDQDMAERIRKHMIAYGMKF-EAGVPTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEV 447
Query: 282 IDNVDSLIWTIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVV-GKVE 339
+ ++++ IGR ++ +GL IGV+ ++++ Q++++ VY++GDV+ G E
Sbjct: 448 SEEYNTILMAIGREAVTDDVGLTTIGVERAKSKKVLGRREQSTTIPWVYAIGDVLEGTPE 507
Query: 340 LTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDN 399
LTPVAI AGR L R+F N+ +Y+ +P+ VF+ E G GLSE +A+ K+GKDN
Sbjct: 508 LTPVAIQAGRVLMRRIFDG---ANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDN 564
Query: 400 VKVYNSKFNAMYYAMMEEKDKTPTRYKLVC-TGEEEKVVGLHIIGDSSAEILQGFGVAIK 458
+ +Y++ FN + Y + E DK K++C EEEKVVG HI+ ++ E+ QGFG+A+K
Sbjct: 565 IIIYHNVFNPLEYTISERMDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALK 624
Query: 459 MGATKADFDSCVAIHPTSAEELVTLT 484
+ A KADFD + IHPT AE TLT
Sbjct: 625 LAAKKADFDRLIGIHPTVAENFTTLT 650
>7290913 [O] KOG4716 Thioredoxin reductase
Length = 491
Score = 256 bits (654), Expect = 5e-68
Identities = 157/435 (36%), Positives = 253/435 (58%), Gaps = 20/435 (4%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M AS L + A +Y D E + +W + + +I
Sbjct: 53 VGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVD-----EKIKPDWHKLVQSVQNHI 107
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYPA 175
+N + +L + V+Y+ G SF VD + K + T TA ++A GG+P YP
Sbjct: 108 KSVNWVTRVDLRDKKVEYINGLGSF-VDSHTLLAKLKSGERTITAQTFVIAVGGRPRYP- 165
Query: 176 KIPG-YDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRK 234
IPG +YG++SD+ F L+ +P K +VVGAGYIG+E AG GLG + +++R VLR
Sbjct: 166 DIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVR-SIVLRG 224
Query: 235 FDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQ---LDTGKNIDNV-DSLIW 290
FD + E V + + G+ + + VEK + GKL ++ ++TG+ ++V D+++W
Sbjct: 225 FDQQMAELVAASMEERGIPFLRKTVPLSVEKQDD-GKLLVKYKNVETGEEAEDVYDTVLW 283
Query: 291 TIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVV-GKVELTPVAIAAG 348
IGR+ L+ L L N GV + K++I VD + ++V N+Y++GD++ GK ELTPVA+ AG
Sbjct: 284 AIGRKGLVDDLNLPNAGVTVQ-KDKIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAG 342
Query: 349 RKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKFN 408
R L+ RL+G Q+ DY++V + VF+ E +GLSE +A+++FG D ++V++ +
Sbjct: 343 RLLARRLYGG---STQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYK 399
Query: 409 AMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATKADFDS 468
+ + ++ + + +++V GLH IG + E++QGF A+K G T +
Sbjct: 400 PTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLIN 459
Query: 469 CVAIHPTSAEELVTL 483
V IHPT+AEE L
Sbjct: 460 TVGIHPTTAEEFTRL 474
>CE15373 [O] KOG4716 Thioredoxin reductase
Length = 503
Score = 248 bits (634), Expect = 1e-65
Identities = 147/435 (33%), Positives = 250/435 (56%), Gaps = 18/435 (4%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTC N GC+PKK+M A+ + + HA Y + +E + +W K + +
Sbjct: 63 IGGTCANVGCIPKKLMHQAAIVGKELKHADKYGWNG---IDQEKIKHDWNVLSKNVNDRV 119
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKAD-NCTETY-TADHILVATGGKPIY 173
N IY L ++ ++Y +A F K+ + D N T+ + +A +++++TG +P Y
Sbjct: 120 KANNWIYRVQLNQKKINYFNAYAEFVDKDKIVITGTDKNKTKNFLSAPNVVISTGLRPKY 179
Query: 174 PAKIPGYDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLR 233
P IPG + G++SD+ F L P K ++VG GY+ +E AG + + +++R L+
Sbjct: 180 P-NIPGAELGITSDDLFTLASVPGKTLIVGGGYVALECAGFLSAFNQNVEVLVRS-IPLK 237
Query: 234 KFD-DCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDTGKNIDNVDSLIWTI 292
FD DC+ V + GV + + V +VE S K+ + G ++ D++IW
Sbjct: 238 GFDRDCVH-FVMEHLKTTGVKVKEHVEVERVEAVGSKKKVTFTGNGG--VEEYDTVIWAA 294
Query: 293 GR-RSLLGLGLENIGVKLDAKE-QIVVDEYQNSSVKNVYSLGDVV-GKVELTPVAIAAGR 349
GR +L L L+N GV+ D + +I+ DE+ +S VY++GD+V + ELTP+AI +G+
Sbjct: 295 GRVPNLKSLNLDNAGVRTDKRSGKILADEFDRASCNGVYAVGDIVQDRQELTPLAIQSGK 354
Query: 350 KLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKFNA 409
L++RLF K Q ++ V + VF+ E ++GL+E EAI+K G+D+++V++S F
Sbjct: 355 LLADRLFSNSK---QIVRFDGVATTVFTPLELSTVGLTEEEAIQKHGEDSIEVFHSHFTP 411
Query: 410 MYYAMMEEKDKTPTRYKLVCTGEE-EKVVGLHIIGDSSAEILQGFGVAIKMGATKADFDS 468
Y + + KD K VCT +E +K++GLH +G ++AE++QG+ VA ++G + +D +
Sbjct: 412 FEYVVPQNKDSGFCYVKAVCTRDESQKILGLHFVGPNAAEVIQGYAVAFRVGISMSDLQN 471
Query: 469 CVAIHPTSAEELVTL 483
+AIHP S+EE V L
Sbjct: 472 TIAIHPCSSEEFVKL 486
>HsM5454136 [O] KOG4716 Thioredoxin reductase
Length = 524
Score = 238 bits (607), Expect = 1e-62
Identities = 156/437 (35%), Positives = 239/437 (53%), Gaps = 20/437 (4%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M A+ L I A +Y P+ + W + + ++
Sbjct: 82 LGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHD-----WRKMAEAVQNHV 136
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYPA 175
LN + L V Y ASF + V +ADHI++ATGG+P YP
Sbjct: 137 KSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPT 196
Query: 176 KIPG-YDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRK 234
I G +YG++SD+ F L++ P K +VVGA Y+ +E AG G+G D+ +++R LR
Sbjct: 197 HIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMR-SIPLRG 255
Query: 235 FDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLD---TGK-NIDNVDSLIW 290
FD + V + G + ++V + G+L + + TGK + D+++W
Sbjct: 256 FDQQMSSMVIEHMASHGTRFLRGCAPSRVRR-LPDGQLQVTWEDSTTGKEDTGTFDTVLW 314
Query: 291 TIGR-RSLLGLGLENIGVKLDAKEQ-IVVDEYQNSSVKNVYSLGDVV-GKVELTPVAIAA 347
IGR L LE GV Q I+VD + +SV ++Y++GDVV G+ ELTP+AI A
Sbjct: 315 AIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMA 374
Query: 348 GRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKF 407
GR L RLFG + DY+NVP+ VF+ E G +GLSE EA+ + G+++V+VY++ +
Sbjct: 375 GRLLVQRLFGG---SSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHY 431
Query: 408 NAMYYAMMEEKDKTPTRYKLVCTGE-EEKVVGLHIIGDSSAEILQGFGVAIKMGATKADF 466
+ + + +D + K+VC E + V+GLH +G ++ E+ QGF + IK GA+ A
Sbjct: 432 KPLEFT-VAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQV 490
Query: 467 DSCVAIHPTSAEELVTL 483
V IHPT +EE+V L
Sbjct: 491 MRTVGIHPTCSEEVVKL 507
>Hs22035672 [O] KOG4716 Thioredoxin reductase
Length = 524
Score = 238 bits (607), Expect = 1e-62
Identities = 156/437 (35%), Positives = 239/437 (53%), Gaps = 20/437 (4%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M A+ L I A +Y P+ + W + + ++
Sbjct: 82 LGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHD-----WRKMAEAVQNHV 136
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYPA 175
LN + L V Y ASF + V +ADHI++ATGG+P YP
Sbjct: 137 KSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPT 196
Query: 176 KIPG-YDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRK 234
I G +YG++SD+ F L++ P K +VVGA Y+ +E AG G+G D+ +++R LR
Sbjct: 197 HIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMR-SIPLRG 255
Query: 235 FDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLD---TGK-NIDNVDSLIW 290
FD + V + G + ++V + G+L + + TGK + D+++W
Sbjct: 256 FDQQMSSMVIEHMASHGTRFLRGCAPSRVRR-LPDGQLQVTWEDSTTGKEDTGTFDTVLW 314
Query: 291 TIGR-RSLLGLGLENIGVKLDAKEQ-IVVDEYQNSSVKNVYSLGDVV-GKVELTPVAIAA 347
IGR L LE GV Q I+VD + +SV ++Y++GDVV G+ ELTP+AI A
Sbjct: 315 AIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMA 374
Query: 348 GRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKF 407
GR L RLFG + DY+NVP+ VF+ E G +GLSE EA+ + G+++V+VY++ +
Sbjct: 375 GRLLVQRLFGG---SSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHY 431
Query: 408 NAMYYAMMEEKDKTPTRYKLVCTGE-EEKVVGLHIIGDSSAEILQGFGVAIKMGATKADF 466
+ + + +D + K+VC E + V+GLH +G ++ E+ QGF + IK GA+ A
Sbjct: 432 KPLEFT-VAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQV 490
Query: 467 DSCVAIHPTSAEELVTL 483
V IHPT +EE+V L
Sbjct: 491 MRTVGIHPTCSEEVVKL 507
>Hs22035670 [O] KOG4716 Thioredoxin reductase
Length = 494
Score = 238 bits (607), Expect = 1e-62
Identities = 156/437 (35%), Positives = 239/437 (53%), Gaps = 20/437 (4%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M A+ L I A +Y P+ + W + + ++
Sbjct: 52 LGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHD-----WRKMAEAVQNHV 106
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYPA 175
LN + L V Y ASF + V +ADHI++ATGG+P YP
Sbjct: 107 KSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPT 166
Query: 176 KIPG-YDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRK 234
I G +YG++SD+ F L++ P K +VVGA Y+ +E AG G+G D+ +++R LR
Sbjct: 167 HIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMR-SIPLRG 225
Query: 235 FDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLD---TGK-NIDNVDSLIW 290
FD + V + G + ++V + G+L + + TGK + D+++W
Sbjct: 226 FDQQMSSMVIEHMASHGTRFLRGCAPSRVRR-LPDGQLQVTWEDSTTGKEDTGTFDTVLW 284
Query: 291 TIGR-RSLLGLGLENIGVKLDAKEQ-IVVDEYQNSSVKNVYSLGDVV-GKVELTPVAIAA 347
IGR L LE GV Q I+VD + +SV ++Y++GDVV G+ ELTP+AI A
Sbjct: 285 AIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMA 344
Query: 348 GRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKF 407
GR L RLFG + DY+NVP+ VF+ E G +GLSE EA+ + G+++V+VY++ +
Sbjct: 345 GRLLVQRLFGG---SSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHY 401
Query: 408 NAMYYAMMEEKDKTPTRYKLVCTGE-EEKVVGLHIIGDSSAEILQGFGVAIKMGATKADF 466
+ + + +D + K+VC E + V+GLH +G ++ E+ QGF + IK GA+ A
Sbjct: 402 KPLEFT-VAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQV 460
Query: 467 DSCVAIHPTSAEELVTL 483
V IHPT +EE+V L
Sbjct: 461 MRTVGIHPTCSEEVVKL 477
>Hs4507747 [O] KOG4716 Thioredoxin reductase
Length = 497
Score = 235 bits (599), Expect = 1e-61
Identities = 150/440 (34%), Positives = 245/440 (55%), Gaps = 22/440 (5%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M A+ L + + +Y +E + +W + +I
Sbjct: 55 LGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGW-----KVEETVKHDWDRMIEAVQNHI 109
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYPA 175
LN Y L ++ V Y + F +++ + Y+A+ L+ATG +P Y
Sbjct: 110 GSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAESFLIATGERPRYLG 169
Query: 176 KIPG-YDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRK 234
IPG +Y +SSD+ F L P K +VVGA Y+ +E AG G+G +++R +LR
Sbjct: 170 -IPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLGVTVMVR-SILLRG 227
Query: 235 FDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDE--STGKLNIQLDTGKNIDNVD----SL 288
FD + + + + G+ + KVE+ E + G+L + + + + ++ ++
Sbjct: 228 FDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTV 287
Query: 289 IWTIGRRSLL-GLGLENIGVKLDAKE-QIVVDEYQNSSVKNVYSLGDVV-GKVELTPVAI 345
+ IGR + +GLE +GVK++ K +I V + + ++V +Y++GD++ KVELTPVAI
Sbjct: 288 MLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAI 347
Query: 346 AAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNS 405
AGR L+ RL+ K DYENVP+ VF+ E G+ GLSE +A+EKFG++N++VY+S
Sbjct: 348 QAGRLLAQRLYAG---STVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHS 404
Query: 406 KFNAMYYAMMEEKDKTPTRYKLVC-TGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATKA 464
F + + + +D K++C T + E+VVG H++G ++ E+ QGF A+K G TK
Sbjct: 405 YFWPLEWT-IPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKK 463
Query: 465 DFDSCVAIHPTSAEELVTLT 484
DS + IHP AE TL+
Sbjct: 464 QLDSTIGIHPVCAEVFTTLS 483
>Hs20536269 [O] KOG4716 Thioredoxin reductase
Length = 459
Score = 227 bits (578), Expect = 3e-59
Identities = 147/438 (33%), Positives = 236/438 (53%), Gaps = 20/438 (4%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M A+ L + + + + + + NW K +I
Sbjct: 17 LGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYN-----QQVRHNWETMTKAIQNHI 71
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYPA 175
LN Y +L ++ V YV + F K++ YTA ++ATG +P Y
Sbjct: 72 SSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLG 131
Query: 176 KIPGYDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKF 235
+Y ++SD+ F L P K +VVGA Y+ +E AG G G D +++R +LR F
Sbjct: 132 IQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVR-SILLRGF 190
Query: 236 DDCIQETVTDTYIKEGVNIHKSSNVTKVEKDE--STGKLNIQLDTGKNIDNVD----SLI 289
D + E V + GV + V++ E S GKL + + + + ++ +++
Sbjct: 191 DQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYNTVL 250
Query: 290 WTIGRRSLL-GLGLENIGVKLDAKE-QIVVDEYQNSSVKNVYSLGDVV-GKVELTPVAIA 346
IGR S +GLE IGVK++ K +I V++ + ++V VY++GD++ K ELTPVAI
Sbjct: 251 LAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQ 310
Query: 347 AGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSK 406
+G+ L+ RLFG +K DY NVP+ VF+ E G GLSE +AIE + K+N+++Y++
Sbjct: 311 SGKLLAQRLFGASL---EKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTL 367
Query: 407 FNAMYYAMMEEKDKTPTRYKLVCTG-EEEKVVGLHIIGDSSAEILQGFGVAIKMGATKAD 465
F + + + ++ T K++C + ++V+G HI+G ++ E+ QGF A+K G TK
Sbjct: 368 FWPLEWTVAGRENNT-CYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQL 426
Query: 466 FDSCVAIHPTSAEELVTL 483
D + IHPT E TL
Sbjct: 427 LDDTIGIHPTCGEVFTTL 444
>7296552 [O] KOG4716 Thioredoxin reductase
Length = 516
Score = 223 bits (568), Expect = 5e-58
Identities = 143/437 (32%), Positives = 241/437 (54%), Gaps = 19/437 (4%)
Query: 56 MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYI 115
+GGTCVN GC+PKK+M AS L + A +Y D N+ +W + + +I
Sbjct: 75 IGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVD----DTNIRPDWRKLVRSVQNHI 130
Query: 116 HRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETY-TADHILVATGGKPIYP 174
+N + +L + V+YV A+F ++ T+++++VA GG+P YP
Sbjct: 131 KSVNWVTRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYP 190
Query: 175 AKIPG-YDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLR 233
IPG + G++SD+ F E +P + +VVGAGY+G+E A GLG + +++R VLR
Sbjct: 191 -DIPGAVELGITSDDIFSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVR-SIVLR 248
Query: 234 KFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQL-DTGKNIDN---VDSLI 289
FD + E + + G+ + + K + ++ G+L ++ +T +D D+++
Sbjct: 249 GFDRQMSELLAAMMTERGIPF-LGTTIPKAVERQADGRLLVRYRNTTTQMDGSDVFDTVL 307
Query: 290 WTIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVV-GKVELTPVAIAA 347
W IGR+ L+ L L+ GVK ++IVVD + +SV +++++GD++ G+ ELTPVAI +
Sbjct: 308 WAIGRKGLIEDLNLDAAGVKTH-DDKIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILS 366
Query: 348 GRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKF 407
GR L+ RLF Q DY +V + VF+ E +G+SE AIE G DN++V++ +
Sbjct: 367 GRLLARRLFAG---STQLMDYADVATTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYY 423
Query: 408 NAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATKADFD 467
+ + ++ + + ++K++GLH IG + E++QGF A+K G T
Sbjct: 424 KPTEFFIPQKSVRHCYLKAVAEVSGDQKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLL 483
Query: 468 SCVAIHPTSAEELVTLT 484
+ V IHPT+AEE L+
Sbjct: 484 NTVGIHPTTAEEFTRLS 500
>Hs22035668 [O] KOG4716 Thioredoxin reductase
Length = 428
Score = 213 bits (541), Expect = 7e-55
Identities = 138/390 (35%), Positives = 215/390 (54%), Gaps = 15/390 (3%)
Query: 103 NWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADH 162
+W + + ++ LN + L V Y ASF + V +ADH
Sbjct: 28 DWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADH 87
Query: 163 ILVATGGKPIYPAKIPG-YDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSD 221
I++ATGG+P YP I G +YG++SD+ F L++ P K +VVGA Y+ +E AG G+G D
Sbjct: 88 IIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLD 147
Query: 222 SHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLD---T 278
+ +++R LR FD + V + G + ++V + G+L + + T
Sbjct: 148 TTIMMR-SIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRR-LPDGQLQVTWEDSTT 205
Query: 279 GK-NIDNVDSLIWTIGR-RSLLGLGLENIGVKLDAKEQ-IVVDEYQNSSVKNVYSLGDVV 335
GK + D+++W IGR L LE GV Q I+VD + +SV ++Y++GDVV
Sbjct: 206 GKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVV 265
Query: 336 -GKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEK 394
G+ ELTP+AI AGR L RLFG + DY+NVP+ VF+ E G +GLSE EA+ +
Sbjct: 266 EGRPELTPIAIMAGRLLVQRLFGG---SSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVAR 322
Query: 395 FGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGE-EEKVVGLHIIGDSSAEILQGF 453
G+++V+VY++ + + + + +D + K+VC E + V+GLH +G ++ E+ QGF
Sbjct: 323 HGQEHVEVYHAHYKPLEFT-VAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGF 381
Query: 454 GVAIKMGATKADFDSCVAIHPTSAEELVTL 483
+ IK GA+ A V IHPT +EE+V L
Sbjct: 382 ALGIKCGASYAQVMRTVGIHPTCSEEVVKL 411
>At1g48030 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 507
Score = 169 bits (427), Expect = 1e-41
Identities = 127/442 (28%), Positives = 208/442 (46%), Gaps = 24/442 (5%)
Query: 47 KTLLIEAK-AMGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWP 105
KT IE + A+GGTC+N GC+P K + ++S + H+ F + + ++ + P
Sbjct: 68 KTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAKHS-----FANHGIKVSSVEVDLP 122
Query: 106 EFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILV 165
++D + L E K V YV G+ F +V V+ D HI+V
Sbjct: 123 AMLAQKDNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPNEVSVETIDGGNTIVKGKHIIV 182
Query: 166 ATGGKPIYPAKIPGYDYG----VSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSD 221
ATG +PG VSS L + PKK++V+GAGYIG+E+ V+ LGS+
Sbjct: 183 ATGSDV---KSLPGITIDEKKIVSSTGALSLSEVPKKLIVIGAGYIGLEMGSVWGRLGSE 239
Query: 222 SHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDTG-- 279
+V ++ D I++ + K+ + + V V+ KL ++ G
Sbjct: 240 VTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFMLKTKVVSVDSSSDGVKLTVEPAEGGE 299
Query: 280 KNIDNVDSLIWTIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVVGKV 338
++I D ++ + GR GL LE IGV+ D +I+V++ S+V VY++GDV+
Sbjct: 300 QSILEADVVLVSAGRTPFTSGLDLEKIGVETDKAGRILVNDRFLSNVPGVYAIGDVIPGP 359
Query: 339 ELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKD 398
L A G + G K+ DY+ VP VV++HPE S+G +E E+ K+
Sbjct: 360 MLAHKAEEDGVACVEFIAG----KHGHVDYDKVPGVVYTHPEVASVGKTE----EQLKKE 411
Query: 399 NVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIK 458
V KF M + + D K++ E +K++G+HI+ ++ E++ +AI
Sbjct: 412 GVSYRVGKFPFMANSRAKAIDNAEGLVKILADKETDKILGVHIMAPNAGELIHEAVLAIN 471
Query: 459 MGATKADFDSCVAIHPTSAEEL 480
A+ D HPT +E L
Sbjct: 472 YDASSEDIARVCHAHPTMSEAL 493
>At3g17240 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 507
Score = 161 bits (408), Expect = 2e-39
Identities = 124/442 (28%), Positives = 207/442 (46%), Gaps = 24/442 (5%)
Query: 47 KTLLIEAK-AMGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWP 105
KT IE + A+GGTC+N GC+P K + ++S + H +F + + ++ + P
Sbjct: 68 KTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAKH-----VFANHGVKVSSVEVDLP 122
Query: 106 EFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILV 165
++D + L E K V+YV G+ F +V V D HI+V
Sbjct: 123 AMLAQKDTAVKNLTRGVEGLFKKNKVNYVKGYGKFLSPSEVSVDTIDGENVVVKGKHIIV 182
Query: 166 ATGGKPIYPAKIPGYDYG----VSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSD 221
ATG +PG VSS L + PKK++V+GAGYIG+E+ V+ LGS+
Sbjct: 183 ATGSDV---KSLPGITIDEKKIVSSTGALSLTEIPKKLIVIGAGYIGLEMGSVWGRLGSE 239
Query: 222 SHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDTG-- 279
+V ++ D I++ + K+ + + V V+ KL ++ G
Sbjct: 240 VTVVEFAADIVPAMDGEIRKQFQRSLEKQKMKFMLKTKVVGVDSSGDGVKLIVEPAEGGE 299
Query: 280 KNIDNVDSLIWTIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVVGKV 338
+ D ++ + GR GL LE IGV+ D +I+V+E +++V VY++GDV+
Sbjct: 300 QTTLEADVVLVSAGRTPFTSGLDLEKIGVETDKGGRILVNERFSTNVSGVYAIGDVIPGP 359
Query: 339 ELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKD 398
L A G + G K+ DY+ VP VV+++PE S+G +E E+ K+
Sbjct: 360 MLAHKAEEDGVACVEFIAG----KHGHVDYDKVPGVVYTYPEVASVGKTE----EQLKKE 411
Query: 399 NVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIK 458
V KF M + + D K++ E +K++G+HI+ ++ E++ +AI
Sbjct: 412 GVSYNVGKFPFMANSRAKAIDTAEGMVKILADKETDKILGVHIMSPNAGELIHEAVLAIN 471
Query: 459 MGATKADFDSCVAIHPTSAEEL 480
A+ D HPT +E +
Sbjct: 472 YDASSEDIARVCHAHPTMSEAI 493
>YFL018c [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 499
Score = 155 bits (391), Expect = 2e-37
Identities = 126/472 (26%), Positives = 221/472 (46%), Gaps = 31/472 (6%)
Query: 23 YDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKA-MGGTCVNKGCVPKKVMWYASDLATRI 81
+D ++I T +E + +GGTC+N GC+P K + S L ++
Sbjct: 27 HDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQM 86
Query: 82 GHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFT 141
H + D+ ++ N F+K +D + +L G E K V Y G SF
Sbjct: 87 -HTEAQKRGIDV---NGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFE 142
Query: 142 VDGKVQVKKADNCTETYTADHIL------VATGGKPIYPAKIPGYDYG----VSSDEFFE 191
+ K++V D T DHIL VATG + PG + VSS
Sbjct: 143 DETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEV---TPFPGIEIDEEKIVSSTGALS 199
Query: 192 LEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEG 251
L++ PK++ ++G G IG+E+ V++ LGS +V + D + + K+G
Sbjct: 200 LKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQG 259
Query: 252 VNIHKSSNVTKVEKDESTGKLNIQLDTGKNI--DNVDS--LIWTIGRRSLL-GLGLENIG 306
++ S+ V ++++ + I ++ K +N+++ L+ +GRR + GLG E IG
Sbjct: 260 LDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIG 319
Query: 307 VKLDAKEQIVVDEYQNSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQ 366
+++D + ++V+D+ NS ++ +GDV L A G L K +
Sbjct: 320 LEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEML----KTGHGHV 375
Query: 367 DYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYK 426
+Y N+PSV++SHPE +G +E E +++ G D K+ KF + + T K
Sbjct: 376 NYNNIPSVMYSHPEVAWVGKTE-EQLKEAGID-YKI--GKFPFAANSRAKTNQDTEGFVK 431
Query: 427 LVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSAE 478
++ + E+++G HIIG ++ E++ G+A++ GA+ D HPT +E
Sbjct: 432 ILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSE 483
>Hs4557525 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 509
Score = 153 bits (387), Expect = 5e-37
Identities = 122/445 (27%), Positives = 205/445 (45%), Gaps = 31/445 (6%)
Query: 47 KTLLIEA-KAMGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNL-----FEDLPLTKENL 100
KT+ IE + +GGTC+N GC+P K + + ++H Y++ F + +
Sbjct: 66 KTVCIEKNETLGGTCLNVGCIPSKAL---------LNNSHYYHMAHGTDFASRGIEMSEV 116
Query: 101 TFNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTA 160
N + +++ + L G + V +V G+ T +V KAD T+
Sbjct: 117 RLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDT 176
Query: 161 DHILVATGGKPI-YPAKIPGYDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLG 219
+IL+ATG + +P D VSS L+ P+K+VV+GAG IGVE+ V+ LG
Sbjct: 177 KNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLG 236
Query: 220 SDSHLV-IRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDT 278
+D V G D I + K+G ++ VT K +S GK+++ ++
Sbjct: 237 ADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATK-KSDGKIDVSIEA 295
Query: 279 GK----NIDNVDSLIWTIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGD 333
+ D L+ IGRR LGLE +G++LD + +I V+ + + N+Y++GD
Sbjct: 296 ASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGD 355
Query: 334 VVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIE 393
VV L A G + G DY VPSV+++HPE +G SE E
Sbjct: 356 VVAGPMLAHKAEDEGIICVEGMAGGA----VHIDYNCVPSVIYTHPEVAWVGKSE----E 407
Query: 394 KFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGF 453
+ ++ ++ KF + + T K++ ++V+G HI+G + E++
Sbjct: 408 QLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEA 467
Query: 454 GVAIKMGATKADFDSCVAIHPTSAE 478
+A++ GA+ D HPT +E
Sbjct: 468 ALALEYGASCEDIARVCHAHPTLSE 492
>At3g16950 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 564
Score = 152 bits (385), Expect = 8e-37
Identities = 131/474 (27%), Positives = 216/474 (44%), Gaps = 36/474 (7%)
Query: 23 YDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKAMGGTCVNKGCVPKKVMWYASDLATRIG 82
YD ++I KT +IE +GGTCVN+GCVP K + S +
Sbjct: 87 YDLIIIGAGVGGHGAALHAVEKGLKTAIIEGDVVGGTCVNRGCVPSKALLAVSGRMRELQ 146
Query: 83 HAHSYNLFEDLPLTKENLTFNWPEFKKKRDA-YIHRLNGIYERNLTKE----GVDYVYGW 137
+ H F L + + ++ A + + L NLT GVD + G+
Sbjct: 147 NEHHMKSF--------GLQVSAAGYDRQGVADHANNLATKIRNNLTNSMKAIGVDILTGF 198
Query: 138 ASFTVDGKVQVKKADNCTETYTADHILVATGGKPIYP--AKIPGYDYGVSSDEFFELEDQ 195
S KV+ K DN TA I++ATG P P ++ G ++SD +LE
Sbjct: 199 GSVLGPQKVKYGK-DN---IITAKDIIIATGSVPFVPKGIEVDGKTV-ITSDHALKLESV 253
Query: 196 PKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIK-EGVNI 254
P+ + +VG+GYIG+E + V+ LGS+ + + ++ FD I + I ++
Sbjct: 254 PEWIAIVGSGYIGLEFSDVYTALGSEVTFIEALDQLMPGFDPEISKLAQRVLINPRKIDY 313
Query: 255 HKSSNVTKVEKDESTGKLNIQLDTGKNID-----NVDSLIWTIGRRSLL-GLGLENIGVK 308
H +K+ + I+L K + VD+ + GR GLGLEN G
Sbjct: 314 HTGVFASKITPARDGKPVLIELIDAKTKEPKDTLEVDAALIATGRAPFTNGLGLENRGF- 372
Query: 309 LDAKEQIVVDEYQNSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDY 368
+ E++ V + + + V N+Y +GD GK+ L A A G + ++ G + N +
Sbjct: 373 IPVDERMRVIDGKGTLVPNLYCIGDANGKLMLAHAASAQGISVVEQVSGRDHVLN----H 428
Query: 369 ENVPSVVFSHPEAGSIGLSEREAIEKFGKD--NVKVYNSKFNAMYYAMMEEKDKTPTRYK 426
++P+ F+HPE +GL+E +A EK K+ V V + F A A+ E + + K
Sbjct: 429 LSIPAACFTHPEISMVGLTEPQAKEKGEKEGFKVSVVKTSFKANTKALAENEGEGIA--K 486
Query: 427 LVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSAEEL 480
++ + +++G+HI G +A+++ AI +G D V HPT +E L
Sbjct: 487 MIYRPDNGEILGVHIFGLHAADLIHEASNAIALGTRIQDIKLAVHAHPTLSEVL 540
>7293932 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 504
Score = 151 bits (382), Expect = 2e-36
Identities = 120/447 (26%), Positives = 213/447 (46%), Gaps = 32/447 (7%)
Query: 47 KTLLIEAKA-MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLT---- 101
KT+ +E +A +GGTC+N GC+P K + + ++H Y++ L K ++
Sbjct: 62 KTVSVEKEATLGGTCLNVGCIPSKAL---------LNNSHYYHMAHSGDLEKRGISCGSV 112
Query: 102 -FNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTA 160
+ + ++ + L G K V + G+ + +V+VKK+D TET
Sbjct: 113 SLDLEKLMGQKSNAVKALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSDGSTETVKT 172
Query: 161 DHILVATGGKPI-YPAKIPGYDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLG 219
+IL+ATG + +P + VSS +L PK +VV+GAG IG+E+ V++ LG
Sbjct: 173 KNILIATGSEVTPFPGIEIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELGSVWSRLG 232
Query: 220 SDSHLVIRGETVLRK-FDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDT 278
++ + +T+ D+ + +T K+G+ + VT + S + + ++
Sbjct: 233 AEVTAIEFMDTIGGVGIDNEVSKTFQKVLTKQGLKFKLGTKVTAASR--SGDNVTVSVEN 290
Query: 279 GKNIDN----VDSLIWTIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGD 333
K+ + D+L+ ++GRR GLGLE +G+ D + +I V+ + V N+Y++GD
Sbjct: 291 AKSGEKEEIQCDALLVSVGRRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAIGD 350
Query: 334 VVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIE 393
+ L A G + G + DY VPSVV++HPE +G SE E
Sbjct: 351 CIHGPMLAHKAEDEGLITIEGINGG----HVHIDYNCVPSVVYTHPEVAWVGKSE----E 402
Query: 394 KFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGF 453
+ ++ V KF + + + + T K++ +K++G HIIG + E++
Sbjct: 403 QLKQEGVAYKVGKFPFLANSRAKTNNDTDGFVKVLADQATDKILGTHIIGPGAGELINEA 462
Query: 454 GVAIKMGATKADFDSCVAIHPTSAEEL 480
+A++ GA D HPT +E L
Sbjct: 463 VLAMEYGAAAEDVARVCHAHPTCSEAL 489
>SPAC1002.09c [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 511
Score = 136 bits (342), Expect = 8e-32
Identities = 112/463 (24%), Positives = 202/463 (43%), Gaps = 21/463 (4%)
Query: 23 YDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKA-MGGTCVNKGCVPKKVMWYASDLATRI 81
YD VI KT+ +E + +GGTC+N GC+P K + S + +
Sbjct: 46 YDLCVIGGGPGGYVAAIRGAQLGLKTICVEKRGTLGGTCLNVGCIPSKALLNNSHIYHTV 105
Query: 82 GHAHSYNLFEDLPLTKENLTFNWPEFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFT 141
H + ++ N + K +D + L E K V+Y G SF
Sbjct: 106 KHDTKRR-----GIDVSGVSVNLSQMMKAKDDSVKSLTSGIEYLFKKNKVEYAKGTGSFI 160
Query: 142 VDGKVQVKKADNCTE-TYTADHILVATGG--KPIYPAKIPGYDYGVSSDEFFELEDQPKK 198
+ VK D + T A + ++ATG KP +P VSS L + PKK
Sbjct: 161 DPQTLSVKGIDGAADQTIKAKNFIIATGSEVKP-FPGVTIDEKKIVSSTGALSLSEVPKK 219
Query: 199 VVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSS 258
+ V+G G IG+E+ V++ LG++ +V V D I + ++ K+G+ S+
Sbjct: 220 MTVLGGGIIGLEMGSVWSRLGAEVTVVEFLPAVGGPMDADISKALSRIISKQGIKFKTST 279
Query: 259 NV--TKVEKDESTGKLNIQLDTGKNIDNVDSLIWTIGRRSLL-GLGLENIGVKLDAKEQI 315
+ KV D ++ + + D L+ IGR GLGL+ +G+ +D ++
Sbjct: 280 KLLSAKVNGDSVEVEIENMKNNKRETYQTDVLLVAIGRVPYTEGLGLDKLGISMDKSNRV 339
Query: 316 VVDEYQNSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVV 375
++D +++ ++ +GD L A G + + N Y +P+V+
Sbjct: 340 IMDSEYRTNIPHIRVIGDATLGPMLAHKAEDEGIAAVEYIAKGQGHVN----YNCIPAVM 395
Query: 376 FSHPEAGSIGLSEREAIEKFGKDNVKVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEK 435
++HPE +G++E++A E K + + N+ M+ K++ E ++
Sbjct: 396 YTHPEVAWVGITEQKAKESGIKYRIGTFPFSANSRAKTNMDADGLV----KVIVDAETDR 451
Query: 436 VVGLHIIGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSAE 478
++G+H+IG + E++ +A++ GA+ D HPT +E
Sbjct: 452 LLGVHMIGPMAGELIGEATLALEYGASAEDVARVCHAHPTLSE 494
>CE16262 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 464
Score = 115 bits (287), Expect = 2e-25
Identities = 108/438 (24%), Positives = 192/438 (43%), Gaps = 51/438 (11%)
Query: 47 KTLLIEAKA-MGGTCVNKGCVPKKVMWYASDLATRIGHAHSYNLFEDLPLTKENLTFNWP 105
KT+ +E A +GGTC+N GC+P K + S H + + + N P
Sbjct: 54 KTVCVEKNATLGGTCLNVGCIPSKALLNNSHYLHMAQHDFAARGIDC------TASLNLP 107
Query: 106 EFKKKRDAYIHRLNGIYERNLTKEGVDYVYGWASFTVDGKVQVKKADNCTETYTADHILV 165
+ + + + +L G ++ V +V G+A+ VQ KK D ET A +IL+
Sbjct: 108 KMMEAKSNSVKQLTGGIKQLFKANKVGHVEGFATIVGPNTVQAKKNDGSVETINARNILI 167
Query: 166 ATGGKPI-YPAKIPGYDYGVSSDEFFELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHL 224
A+G + +P VSS L PKK+VV+GAG IG+E+ V+ LG++
Sbjct: 168 ASGSEVTPFPGITIDEKQIVSSTGALSLGQVPKKMVVIGAGVIGLELGSVWQRLGAEVTA 227
Query: 225 V-IRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQ--LDTGKN 281
V G D + + + K+G ++ V ++ ST + ++ D K
Sbjct: 228 VEFLGHVGGMGIDGEVSKNFQRSLTKQGFKFLLNTKVMGASQNGSTITVEVEGAKDGKKQ 287
Query: 282 IDNVDSLIWTIGRRSLL-GLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDVVGKVEL 340
D+L+ ++GRR GLGL N+ + LD + ++ V+E + V +++++GDV+
Sbjct: 288 TLECDTLLVSVGRRPYTEGLGLSNVQIDLDNRGRVPVNERFQTKVPSIFAIGDVIE---- 343
Query: 341 TPVAIAAGRKLSNRLFGPEKFKNQKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNV 400
GP + +H +A G+ E I G V
Sbjct: 344 ----------------GP----------------MLAH-KAEDEGILCVEGIA--GGPGV 368
Query: 401 KVYNSKFNAMYYAMMEEKDKTPTRYKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMG 460
KF + + + + K++ + ++++G+HIIG ++ E++ +A++ G
Sbjct: 369 AYKIGKFPFVANSRAKTNNDQEGFVKVLADKQTDRMLGVHIIGPNAGEMIAEATLAMEYG 428
Query: 461 ATKADFDSCVAIHPTSAE 478
A+ D HPT +E
Sbjct: 429 ASAEDVARVCHPHPTLSE 446
>YPL017c [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 499
Score = 112 bits (280), Expect = 1e-24
Identities = 120/481 (24%), Positives = 202/481 (41%), Gaps = 46/481 (9%)
Query: 23 YDYLVIXXXXXXXXXXXXXXXXXXKTLLIEAKA-MGGTCVNKGCVPKKVMWYASDLATRI 81
YD LVI T ++ +A +GG + G VP K + Y S L
Sbjct: 18 YDVLVIGCGPGGFTAAMQASQAGLLTACVDQRASLGGAYLVDGAVPSKTLLYESYL---- 73
Query: 82 GHAHSYNLFEDLPLTKENLTFNWP---EFKKKRDAYIHR---LNGIYERNLTKEGVDYVY 135
Y L + L ++ T +P + + + A H L +Y+R L+K V
Sbjct: 74 -----YRLLQQQELIEQRGTRLFPAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVYK 128
Query: 136 GWASFTVDGKVQVKKADNCTETYTADHILVATGGKPIY-PAKIPGYDYGVSSDEFFELED 194
G A+F V++ + A +I+VATG I P D +SSD+ L+
Sbjct: 129 GTAAFKDPHHVEIAQRGMKPFIVEAKYIVVATGSAVIQCPGVAIDNDKIISSDKALSLDY 188
Query: 195 QPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEGVNI 254
P + ++G G IG+EIA +FN LGS +V + + D+ + +G+
Sbjct: 189 IPSRFTIMGGGTIGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAF 248
Query: 255 HKSSNVTKVEKDESTGKLNIQL----DTGKNIDNVDSLIWTIGRRSLL-GLGLENIGVKL 309
+ V E D + G+LNI L + + D L+ +IGRR LL GL + +IG L
Sbjct: 249 LLDTRVQLAEAD-AAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIG--L 305
Query: 310 DAKEQIVVDEYQNSSVKNVYSLGDVVGKVELTPVAIAAGRKLSNRLF------GPEKFKN 363
D ++ + + Q S+ Y +G V L P+ + + R G + N
Sbjct: 306 DERDFVENVDVQTQSLLK-YPHIKPIGDVTLGPMLALKAEEQAIRAIQSIGCTGSDGTSN 364
Query: 364 QKQDYENVPSVVFSHPEAGSIGLSEREAIEKFGKDNVKVYNSKF----NAMYYAMMEEKD 419
P+V++ P+ G +G +E E K + + N Y ++ ++
Sbjct: 365 ----CGFPPNVLYCQPQIGWVGYTE----EGLAKARIPYQKGRVLFSQNVRYNTLLPREE 416
Query: 420 KTPTR--YKLVCTGEEEKVVGLHIIGDSSAEILQGFGVAIKMGATKADFDSCVAIHPTSA 477
T K++ + K++G+H+I D + E+L +A+ +G T D HP+ +
Sbjct: 417 NTTVSPFIKVLIDSRDMKILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLS 476
Query: 478 E 478
E
Sbjct: 477 E 477
>CE27373 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase
Length = 549
Score = 60.8 bits (146), Expect = 4e-09
Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 10/187 (5%)
Query: 156 ETYTADHILVATGGKPIYPAKIPGYDYG-------VSSDEFFELEDQPKKVVVVGAGYIG 208
ET +++ATGG + ++PG D V K VV VG+ +IG
Sbjct: 236 ETVVYSKLIIATGGN-VRKLQVPGSDLKNICYLRKVEEANIISNLHPGKHVVCVGSSFIG 294
Query: 209 VEIAGVFNGLGSDSHLVIRGETVLRKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDES 268
+E+A + ++ L F I + + + ++GV ++NV + ++
Sbjct: 295 MEVASALAEKAASVTVISNTPEPLPVFGSDIGKGIRLKFEEKGVKFELAANVVALRGNDQ 354
Query: 269 TGKLNIQLDTGKNIDNVDSLIWTIGRRSLLGLGLENIGVKLDAKEQIVVDEYQNSSVKNV 328
+ L+ GK +D VD L+ IG LE G+KLD + I VDE +++ +
Sbjct: 355 GEVSKVILENGKELD-VDLLVCGIGVTPATKF-LEGSGIKLDNRGFIEVDEKFRTNISYI 412
Query: 329 YSLGDVV 335
+++GDVV
Sbjct: 413 FAMGDVV 419
>At1g63940 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase
Length = 493
Score = 54.7 bits (130), Expect = 3e-07
Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 163 ILVATGGKPI-YPAKIPGYDYGV-------SSDEFFELEDQPKKVVVVGAGYIGVEIAGV 214
+++ATG +P KI G+ GV +D + KK+V+VG GYIG+E+A
Sbjct: 175 LIIATGCTASRFPDKIGGHLPGVHYIREVADADSLIASLGKAKKIVIVGGGYIGMEVAAA 234
Query: 215 FNGLGSDSHLVIRGETVL-RKFDDCIQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLN 273
D+ +V + +L R F + + + Y + GV K +++ +E
Sbjct: 235 AVAWNLDTTIVFPEDQLLQRLFTPSLAQKYEELYRQNGVKFVKGASINNLEAGSDGRVSA 294
Query: 274 IQLDTGKNIDNVDSLIWTIGRRSLLGLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGD 333
++L G I+ D+++ IG + +G E + + + I VD +S ++++GD
Sbjct: 295 VKLADGSTIE-ADTVVIGIGAKPAIG-PFETLAMN-KSIGGIQVDGLFRTSTPGIFAIGD 351
Query: 334 V 334
V
Sbjct: 352 V 352
>At3g09940 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase
Length = 441
Score = 50.1 bits (118), Expect = 8e-06
Identities = 53/229 (23%), Positives = 97/229 (42%), Gaps = 35/229 (15%)
Query: 128 KEGVDYVYGWASFTVDGKVQVKKADNCTETYTADH--------ILVATGGKPIYPAKIPG 179
++G+D + G ++ KAD ++T +D +L+ATG I ++I
Sbjct: 85 EKGIDLIVG---------TEIVKADLASKTLVSDDGKIYKYQTLLIATGSTNIRLSEIGV 135
Query: 180 YDYGVS----------SDEF---FELEDQPKKVVVVGAGYIGVEIAGVFNGLGSDSHLVI 226
+ V SDE EL Q K V++G G++G+EI+ + +V
Sbjct: 136 QEADVKNIFYLREIEDSDELALAMELYVQRGKAVIIGGGFLGLEISSALRANNHEVTMVF 195
Query: 227 RGETVLRKFDDC-IQETVTDTYIKEGVNIHKSSNVTKVEKDESTGKLNIQLDTGKNIDNV 285
++ +F I Y +G+ I K + T + ++L+ G+ ++
Sbjct: 196 PEPWLVHRFFTAEIASFYESYYANKGIKIIKGTVATGFSTNSDGEVTEVKLEDGRTLE-A 254
Query: 286 DSLIWTIGRRSLLGLGLENIGVKLDAKEQIVVDEYQNSSVKNVYSLGDV 334
+ ++ +G R L G + K I D + +SV +VY+LGDV
Sbjct: 255 NIVVAGVGARPATSLFK---GQLEEEKGGIKTDGFFKTSVPDVYALGDV 300
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,298,714
Number of Sequences: 60738
Number of extensions: 1231942
Number of successful extensions: 2423
Number of sequences better than 1.0e-05: 28
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2274
Number of HSP's gapped (non-prelim): 29
length of query: 484
length of database: 30,389,216
effective HSP length: 110
effective length of query: 374
effective length of database: 23,708,036
effective search space: 8866805464
effective search space used: 8866805464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)