ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV6418 good R KOG0254 General function prediction only Predicted transporter (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV6418 2200867 2201874 336
(336 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator... 357 1e-98
SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator ... 183 4e-46
YEL065w [R] KOG0254 Predicted transporter (major facilitator sup... 158 1e-38
YHL040c [R] KOG0254 Predicted transporter (major facilitator sup... 157 3e-38
SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator ... 154 1e-37
YKR106w [R] KOG0254 Predicted transporter (major facilitator sup... 150 3e-36
YCL073c [R] KOG0254 Predicted transporter (major facilitator sup... 150 3e-36
YOL158c [R] KOG0254 Predicted transporter (major facilitator sup... 147 2e-35
YHL047c [R] KOG0254 Predicted transporter (major facilitator sup... 137 3e-32
YPR198w [R] KOG0254 Predicted transporter (major facilitator sup... 74 4e-13
YMR088c [R] KOG0254 Predicted transporter (major facilitator sup... 70 6e-12
SPBC3E7.06c [R] KOG0254 Predicted transporter (major facilitator... 69 1e-11
SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitato... 62 9e-10
YKR105c [R] KOG0254 Predicted transporter (major facilitator sup... 62 2e-09
SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitato... 59 8e-09
SPAC1399.02 [R] KOG0254 Predicted transporter (major facilitator... 55 1e-07
CE25762 [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 52 1e-06
SPAC3H1.06c [R] KOG0254 Predicted transporter (major facilitator... 52 2e-06
>SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 630
Score = 357 bits (917), Expect = 1e-98
Identities = 175/330 (53%), Positives = 239/330 (72%), Gaps = 8/330 (2%)
Query: 7 WLFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKIS 66
+ F I+I S+ A+ ++TTYSYQ YAT+SFNR SM+STL IA ++I +VC+P + K S
Sbjct: 85 YAFGIAILACSWASAIQSSTTYSYQVYATASFNRTSMISTLEIATAIISSVCKPILGKFS 144
Query: 67 DISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKL 126
DI+SRP TY +VL+ YVIGFI+ A S TI+AYVIGSVFI+IG SGL +N++VV D+T L
Sbjct: 145 DITSRPMTYTLVLLFYVIGFIVVASSSTISAYVIGSVFISIGSSGLDYLNTLVVGDLTSL 204
Query: 127 KWRSLFTSFLSVPYLVTTWISGYLTQHFISTNWRWGYGMFAILTPAVLTPAIIMISWLDR 186
KWR T+ LS PY+ T W +G++ Q I +NWRWGYGMFAI+ PAV+TPA+I++ +L+R
Sbjct: 205 KWRGFMTALLSTPYIATVWFTGFIVQGIIDSNWRWGYGMFAIIMPAVMTPAVIILMYLER 264
Query: 187 KANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLML 246
+ANK ++ E+K KQS+ W L K A++E+D FGL+LLG +S++L
Sbjct: 265 QANKDENIKKIINYQTEEKNKNKQSK------WQKLWK-AVLEVDLFGLILLGVGWSILL 317
Query: 247 IPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFICCVI 306
+P SL SYA GW NPSMIAM VVGG++LI Y+ YE++ AP+P P+RV+ NRTFI VI
Sbjct: 318 LPFSLTSYAKNGWKNPSMIAMMVVGGVILIAYSGYEMFIAPYPSCPRRVM-NRTFITAVI 376
Query: 307 IDFIYQMGGYFSLLYFTSYTSVVLNLSIQD 336
IDF Y + GY +YFT+YT ++ + S +D
Sbjct: 377 IDFFYYLAGYLQSMYFTTYTWILYDWSYRD 406
>SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 612
Score = 183 bits (464), Expect = 4e-46
Identities = 105/332 (31%), Positives = 174/332 (51%), Gaps = 32/332 (9%)
Query: 6 FWLFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKI 65
F++ SIFL F ++ A YS YATS+F HS++ST+ +AN++I A +P +A++
Sbjct: 93 FYICYFSIFLLFFAISFQAECYYSLTAYATSAFAGHSLLSTIAVANNIISAAIKPPLARL 152
Query: 66 SDISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTK 125
SD+ R + L+LY++G I+ A S + Y GSV G +G+ L+ +I +AD +
Sbjct: 153 SDVFGRLEAFLFSLLLYLVGLILMAASTNVQTYAGGSVLYNAGYTGVELIMTIFMADTSS 212
Query: 126 LKWRSLFTSFLSVPYLVTTWISGYLTQHF-ISTNWRWGYGMFAILTPAVLTPAIIMISWL 184
+ RSL +P++VT WI + Q F + + WRWG ++ IL PA P + + S+
Sbjct: 213 MANRSLVLGISYLPFVVTIWIGPRVAQEFYMHSTWRWGIAVWTILIPACSIPFLAVYSYY 272
Query: 185 DRKANKSG--ETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAF 242
+A + G + + ++P+ K+L D GL+L+
Sbjct: 273 QFRAWREGALKGTLTINPVELFKKL-----------------------DIIGLILMTAGL 309
Query: 243 SLMLIPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFI 302
+L+L+ SL SY G W++ I M ++GG+ LI + +YEI+ A FP LP R++ T
Sbjct: 310 ALVLLSISLASYDTGKWSDAKFIVMIIIGGLCLIAFVLYEIFVASFPALPFRLMREPTIG 369
Query: 303 CCVIIDFIYQM------GGYFSLLYFTSYTSV 328
C + F++ + Y+S L YTS+
Sbjct: 370 ACCAMSFLFYITFYCWDNYYYSFLQVVHYTSI 401
>YEL065w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 628
Score = 158 bits (399), Expect = 1e-38
Identities = 95/325 (29%), Positives = 167/325 (51%), Gaps = 12/325 (3%)
Query: 12 SIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISSR 71
S+FL ++ LD Y++Q YATSS+++HS++ST+ +VI AV Q F A++SDI R
Sbjct: 76 SLFLIAYAYGLDGNIRYTFQAYATSSYSQHSLLSTVNCIKTVIAAVGQIFFARLSDIFGR 135
Query: 72 PTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRSL 131
+ V ++ Y +G II + + I + +G F +G +G+ L+ ++ +D + L WR L
Sbjct: 136 FSIMIVSIIFYSMGTIIESQAVNITRFAVGGCFYQLGLTGIILILEVIASDFSNLNWRLL 195
Query: 132 FTSFLSVPYLVTTWISGYLTQHFISTNWRWGYGMFAILTPAVLTPAIIMISWLDRKANKS 191
++P+++ TWISG +T I NW+WG GM+A + P P I + + A K
Sbjct: 196 ALFIPALPFIINTWISGNVTS-AIDANWKWGIGMWAFILPLACIPLGICMLHMRYLARKH 254
Query: 192 GETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLMLIPCSL 251
+ + + A K K ID + W ++D G++L+ F +L+P +L
Sbjct: 255 AKDRLKPEFEALNKLKWKSFCID-IAFW---------KLDIIGMLLITVFFGCVLVPFTL 304
Query: 252 YSYAVGGWNNPSMIAMEVVGGILLI-CYAVYEIWFAPFPLLPKRVLTNRTFICCVIIDFI 310
W +I EV+G ++++ Y ++EI ++ PL P ++ +R ++I F
Sbjct: 305 AGGLKEEWKTAHIIVPEVIGWVVVLPLYMLWEIKYSRHPLTPWDLIQDRGIFFALLIAFF 364
Query: 311 YQMGGYFSLLYFTSYTSVVLNLSIQ 335
Y Y + V ++ SI+
Sbjct: 365 INFNWYMQGDYMYTVLVVAVHESIK 389
>YHL040c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 627
Score = 157 bits (396), Expect = 3e-38
Identities = 93/329 (28%), Positives = 166/329 (50%), Gaps = 11/329 (3%)
Query: 8 LFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISD 67
+ +S F+ + LD Y Y YATSS++ HS++ST+ + N+V+ A Q A++SD
Sbjct: 76 ILLLSAFICGYGYGLDGNIRYIYTGYATSSYSEHSLLSTINVINAVVSAASQIIYARLSD 135
Query: 68 ISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLK 127
+ R + ++LYV+G II + + + Y G++F G G+ L+ I+++D + LK
Sbjct: 136 VFGRLYLFISAVILYVVGTIIQSQAYDVQRYAAGAIFYNAGYVGVILILLIILSDFSSLK 195
Query: 128 WRSLFTSFLSVPYLVTTWISGYLTQHFIS-TNWRWGYGMFAILTPAVLTPAIIMISWLDR 186
WR L+ + P+++ TWI+G +T NW W GM+A + P P ++ + +
Sbjct: 196 WRLLYQFVPTWPFIINTWIAGNITSRANPVVNWSWDVGMWAFIFPLSCVPIVLCMLHMQW 255
Query: 187 KANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLML 246
+A K TP E L Q ++ +LK +D G++L+G + +L
Sbjct: 256 RARK---TP-------EWHALKGQKSYYQEHGFIKILKQLFWMLDVVGVLLMGCSLGCIL 305
Query: 247 IPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFICCVI 306
+P +L WN+ +I V+G +L+ ++E FA P+LP R++ +R +
Sbjct: 306 VPLTLAGGVKTTWNDSRLIGPFVLGFVLIPILWIWEYRFARDPILPYRLVKDRAVWSSMG 365
Query: 307 IDFIYQMGGYFSLLYFTSYTSVVLNLSIQ 335
I F+ Y + Y + V +N S++
Sbjct: 366 ISFLIDFIYYMAADYLYTVMIVAVNESVK 394
>SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 597
Score = 154 bits (390), Expect = 1e-37
Identities = 95/327 (29%), Positives = 166/327 (50%), Gaps = 14/327 (4%)
Query: 11 ISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISS 70
+ ++L SF +L+ TTYS Q YATS+F+ HS ++T+ + +++ AV + + K +D+
Sbjct: 70 LGLYLLSFASSLEQQTTYSLQRYATSNFSAHSNLATINLVGNILLAVVRAPMVKAADVFG 129
Query: 71 RPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRS 130
R + ++ L + V+G++ A S I + + + GQ+GL L++ +++AD + L R
Sbjct: 130 RSESLSLALGMTVLGYLSLAFSRNIQMFTVAYILYICGQTGLGLLSQLIIADTSSLLNRG 189
Query: 131 LFTSFLSVPYLVTTWISGYLTQHF---ISTNWRWGYGMFAILTPAVLTPAIIMISWLDRK 187
+ ++ +PYL T WI L Q F + WR GYG++A + P V P + + RK
Sbjct: 190 ILSAIPELPYLATVWIGPVLAQAFHPEKNYGWRLGYGIWAFILPTVSLPLLASLFLNQRK 249
Query: 188 ANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLMLI 247
A +G E LI S + LR + + + E+D G+VL F+L+L+
Sbjct: 250 AKAAG-------LYREHHNLINHSTPEKLRLFYLFWQ----ELDGLGIVLFVSGFTLLLL 298
Query: 248 PCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFICCVII 307
P S S V + + + LL+ Y++ +A +P+ + L +RT + ++
Sbjct: 299 PFSHSSQVVSPDSTILTLFTITLSIALLVTLCFYDVKYARYPVFALKSLKDRTILGSCVL 358
Query: 308 DFIYQMGGYFSLLYFTSYTSVVLNLSI 334
F Y M Y + TS+ V LSI
Sbjct: 359 IFTYFMSYYIFSNFLTSFLQVSYGLSI 385
>YKR106w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 150 bits (379), Expect = 3e-36
Identities = 93/333 (27%), Positives = 166/333 (48%), Gaps = 15/333 (4%)
Query: 5 YFWLFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAK 64
Y L + F+ F ++LD T +Y YAT+S++ HS++ST+ + N+V+ Q ++
Sbjct: 58 YKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSR 117
Query: 65 ISDISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMT 124
+SD R + V + Y++G II + + + Y GSVF G G +L+ +++++D +
Sbjct: 118 LSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFS 177
Query: 125 KLKWRSLFTSFLSVPYLVTTWISG-YLTQHFISTNWRWGYGMFAILTPAVLTPAIIMISW 183
LKWR + PY++ WISG +T NW W M+A + P P I +I +
Sbjct: 178 SLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSTLPIIFLILY 237
Query: 184 LDRKANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFS 243
+ K++K+ E K ++ GL L+ L ++D G++L+ +
Sbjct: 238 MKYKSSKTAE-------WRSLKEQARKERTGGLFENLVFL---FWKLDIVGILLITVSLG 287
Query: 244 LMLIPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFIC 303
+L+P +L + W+N +IA V GG L + +E FA PLLP ++L++R
Sbjct: 288 CILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWA 347
Query: 304 CVIIDFIYQMGGYFSLLYFTSYTSVVLNLSIQD 336
+ + F +F+ Y VL +S+++
Sbjct: 348 PLGVTFF----NFFTFFISCDYLYPVLLVSMKE 376
>YCL073c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 150 bits (379), Expect = 3e-36
Identities = 93/333 (27%), Positives = 166/333 (48%), Gaps = 15/333 (4%)
Query: 5 YFWLFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAK 64
Y L + F+ F ++LD T +Y YAT+S++ HS++ST+ + N+V+ Q ++
Sbjct: 58 YKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSR 117
Query: 65 ISDISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMT 124
+SD R + V + Y++G II + + + Y GSVF G G +L+ +++++D +
Sbjct: 118 LSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFS 177
Query: 125 KLKWRSLFTSFLSVPYLVTTWISG-YLTQHFISTNWRWGYGMFAILTPAVLTPAIIMISW 183
LKWR + PY++ WISG +T NW W M+A + P P I +I +
Sbjct: 178 SLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSALPIIFLILY 237
Query: 184 LDRKANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFS 243
+ K++K+ E K ++ GL L+ L ++D G++L+ +
Sbjct: 238 MKYKSSKTAE-------WRSLKEQARKERTGGLFENLVFL---FWKLDIVGILLITVSLG 287
Query: 244 LMLIPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFIC 303
+L+P +L + W+N +IA V GG L + +E FA PLLP ++L++R
Sbjct: 288 CILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWA 347
Query: 304 CVIIDFIYQMGGYFSLLYFTSYTSVVLNLSIQD 336
+ + F +F+ Y VL +S+++
Sbjct: 348 PLGVTFF----NFFTFFISCDYLYPVLLVSMKE 376
>YOL158c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 606
Score = 147 bits (371), Expect = 2e-35
Identities = 92/327 (28%), Positives = 159/327 (48%), Gaps = 17/327 (5%)
Query: 11 ISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISS 70
+++FL + L + S Q YA +SF +HS V ++ S++ +V A+ISD
Sbjct: 68 VALFLQGYCTGLGGQISQSIQTYAANSFGKHSQVGSINTVKSIVASVVAVPYARISDRFG 127
Query: 71 RPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRS 130
R + LVLY IG II+A +PT + G V G SG L+ + + D++ L+ R+
Sbjct: 128 RIECWIFALVLYTIGEIISAATPTFSGLFAGIVIQQFGYSGFRLLATALTGDLSGLRDRT 187
Query: 131 LFTSFLSVPYLVTTWISGYLTQHFIST----NWRWGYGMFAILTPAVLTPAIIMISWLDR 186
+ +P ++ TW+SG + WRWGYG+F I+ P ++ +
Sbjct: 188 FAMNIFLIPVIINTWVSGNIVSSVAGNVAPYKWRWGYGIFCIIVPISTLILVLPYVYAQY 247
Query: 187 KANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLML 246
+ +SG+ P L EK + ++Q+ L K A +I+ G++L L+L
Sbjct: 248 ISWRSGKLP--PLKLKEKGQTLRQT----------LWKFA-DDINLIGVILFTAFLVLVL 294
Query: 247 IPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFICCVI 306
+P ++ A W +IAM VVGG L + ++E+ FA P +P+ L + T ++
Sbjct: 295 LPLTIAGGATSKWREGHIIAMIVVGGCLGFIFLIWELKFAKNPFIPRVYLGDPTIYVALL 354
Query: 307 IDFIYQMGGYFSLLYFTSYTSVVLNLS 333
++F++++G L Y + V S
Sbjct: 355 MEFVWRLGLQIELEYLVTVLMVAFGES 381
>YHL047c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 637
Score = 137 bits (344), Expect = 3e-32
Identities = 93/320 (29%), Positives = 153/320 (47%), Gaps = 26/320 (8%)
Query: 8 LFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISD 67
+F S F+ +F LD++ +Y YA +S++ HS++ST+++ +I AV Q +SD
Sbjct: 71 IFLFSAFICTFAYGLDSSIRGTYMTYAMNSYSAHSLISTVSVIVLMISAVSQVIFGGLSD 130
Query: 68 ISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLK 127
I R T + V +VLY++G II + + + Y G+VF +G G+ L ++++D + LK
Sbjct: 131 IFGRLTLFLVSIVLYIVGTIIQSQAYDVQRYAAGAVFYYVGLVGVMLQVVLMLSDNSSLK 190
Query: 128 WRSLFTSFLSVPYLVTTWISGYLTQHFIS-TNWRWGYGMFAILTPAVLTPAIIMISWLDR 186
WR +T S P ++TTW+SG + + NW W M+A + P P I+ + +
Sbjct: 191 WRLFYTLIPSWPSIITTWVSGSVVEAANPLENWSWNIAMWAFIFPLCCIPLILCMLHMRW 250
Query: 187 KANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLML 246
K E K L + + +L ++D G++L +L
Sbjct: 251 KVRND----------VEWKELQDEKSYYQTHGLVQMLVQLFWKLDVVGVLLFTAGVGCIL 300
Query: 247 IPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYE-----IWFAPFPLLPKR----VLT 297
+P +L W N +I V+G +L+ + +E + FAPF LL R L
Sbjct: 301 VPLTLAGGVSTNWRNSKIIGPFVLGFVLVPGFIYWESRLALVPFAPFKLLKDRGVWAPLG 360
Query: 298 NRTFICCVIIDFIYQM-GGY 316
FIC F+YQM GY
Sbjct: 361 IMFFIC-----FVYQMAAGY 375
>YPR198w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 543
Score = 73.6 bits (179), Expect = 4e-13
Identities = 66/288 (22%), Positives = 125/288 (42%), Gaps = 26/288 (9%)
Query: 8 LFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISD 67
L IS+ LT F+ ALD + F+ + L ++ AV ++++
Sbjct: 9 LCVISLLLTLFLAALDIVIVVTLYDTIGIKFHDFGNIGWLVTGYALSNAVFMLLWGRLAE 68
Query: 68 ISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLK 127
I + ++++ IG +I+A S ++A + G V G SG+ + +V + +
Sbjct: 69 ILGTKECLMISVIVFEIGSLISALSNSMATLISGRVVAGFGGSGIESLAFVVGTSIVREN 128
Query: 128 WRSLFTSFLSVPYLVT----TWISGYLTQHFISTNWRWGYGMFAILTPAVLTPAIIMISW 183
R + + L++ Y++ +I G +H +WRW F I P II+
Sbjct: 129 HRGIMITALAISYVIAEGVGPFIGGAFNEHL---SWRW---CFYINLPIGAFAFIILAF- 181
Query: 184 LDRKANKSGETPIGVDPLAEKKRLIKQSEIDGLRA--WLILLKGALIEIDAFGLVLLGFA 241
N SGE + ++ K+++ + L+A W + + ++D G++L
Sbjct: 182 ----CNTSGEPHQKMWLPSKIKKIMNYDYGELLKASFWKNTFEVLVFKLDMVGIILSSAG 237
Query: 242 FSLMLIPCSLYSYAVGG----WNNPSMIAMEVVGGILLICYAVYEIWF 285
F+L+++ S GG WN+ +I VG ILL+ + Y+ F
Sbjct: 238 FTLLMLGLSF-----GGNNFPWNSGIIICFFTVGPILLLLFCAYDFHF 280
>YMR088c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 562
Score = 69.7 bits (169), Expect = 6e-12
Identities = 69/324 (21%), Positives = 131/324 (40%), Gaps = 38/324 (11%)
Query: 12 SIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISSR 71
S++L SF+ +LD+T + F+ S + + + QP K+SDI+ R
Sbjct: 41 SLWLGSFLSSLDSTIVANIMNRVAEEFSESSKKQWIATSFLLTNTAFQPLYGKLSDITGR 100
Query: 72 PTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRSL 131
+ + +G ++T + + + I IG GL+ ++SI V+D+ + R +
Sbjct: 101 KSALLTAQFFFGLGCLLTCFARNVTEFSIARAICGIGAGGLNAISSIAVSDICTARERGV 160
Query: 132 FTSFLSVPYLVTTWISGYLTQHFIST-NWRWGYGMFAILTPAVLTPAIIMISWLDRKANK 190
+ + ++ + + L FI T WR +F I P ++ +++ I ++ K
Sbjct: 161 YQGYANIVFGFGQLLGAPLGGVFIETIGWR---ALFGIQVPVIMLCSVLAIKNINIKL-- 215
Query: 191 SGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLMLIPCS 250
V P+ E+ L L ID FG + L S +L CS
Sbjct: 216 -----FHVPPMKERYTLKN-----------------LSRIDIFGSLSLVATISGVLFLCS 253
Query: 251 LYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFICCVIIDFI 310
N +A+ +G I + + E ++A +LP +LT R+F + I
Sbjct: 254 -------SQLNKLYLALFTIGS--FIVFILVERYYATEKILPFELLT-RSFCLSSAVTVI 303
Query: 311 YQMGGYFSLLYFTSYTSVVLNLSI 334
+ + Y ++ N+S+
Sbjct: 304 SSFVVFGEIFRSPIYLQLLQNISV 327
>SPBC3E7.06c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 577
Score = 68.6 bits (166), Expect = 1e-11
Identities = 66/310 (21%), Positives = 118/310 (37%), Gaps = 42/310 (13%)
Query: 12 SIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISSR 71
++ L + ALD T S + F + S VS A + QP K DI R
Sbjct: 94 ALLLGVVLAALDNTIVASTYTKIGAEFGKFSQVSWTATAYMISCTAFQPLFGKFCDIYGR 153
Query: 72 PTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRSL 131
T ++ IG + S ++ V IG G++ SI+++D+ LK R
Sbjct: 154 KKTLLAAYCVFGIGCFLCGTSRSLWQLVAARAIAGIGGGGMNSTVSILMSDIVPLKQRGT 213
Query: 132 FTSFLSVPYLVTTWISGYLTQHFIST-NWRWGYGMFAILTPAVLTPAIIMISWLDRKANK 190
+ ++V + + + + G + +F WR G F I P + + + L+ +
Sbjct: 214 YQGIINVFFAIGSSLGGPVGGYFADQYTWRIG---FLIQVPLIAIAFLCVYFTLNLPHHN 270
Query: 191 SGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLMLIPCS 250
+ +ID GL+LL + M
Sbjct: 271 H-----------------------------VSFMTRFRKIDLKGLILLIIGVTTMTC--- 298
Query: 251 LYSYAVGG----WNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRTFICCVI 306
++ +GG WN+P +I++ + I + + E + A PL P VLT RT + +
Sbjct: 299 --AFTLGGNVREWNDPVVISLLIASSISYLSFVYVEAFVAFEPLAPMDVLTERTCLSSYL 356
Query: 307 IDFIYQMGGY 316
+F + + +
Sbjct: 357 CNFFHSVANF 366
>SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 531
Score = 62.4 bits (150), Expect = 9e-10
Identities = 63/298 (21%), Positives = 112/298 (37%), Gaps = 40/298 (13%)
Query: 7 WLFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKIS 66
W ++++ F+ ALD T S P S F + S + A + QP ++S
Sbjct: 31 WTILPALWVGGFLSALDMTIVASLYPVIGSEFKLMNNASYIVTAYLITNTAFQPLYGRLS 90
Query: 67 DISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKL 126
DI R T + +G S ++ + IG GL M+SI+ +D+ L
Sbjct: 91 DIFGRRPTVVFANAAFTLGTFWCGISRSLPELCMARALAGIGGGGLGTMSSIISSDIVSL 150
Query: 127 KWRSLFTSFLSVPYLVTTWISGYLTQHFISTNWRWGYGMFAILTPAVLTPAIIMISWLDR 186
+ R + ++ + + + G L I+ W W + +L + I+++W R
Sbjct: 151 RERGTWQGITNIVWGIGGSLGGPL-GGLIAQRWGWRTAFHFQVPMGIL--STILVAWRVR 207
Query: 187 KANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLML 246
V P S ID L ++L++ G+ L F++
Sbjct: 208 -----------VKPTVRNSNASLLSRIDYLGSFLLVT----------GITALVVTFNM-- 244
Query: 247 IPCSLYSYAVGG----WNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRT 300
GG W +P +I + V ++L + E A P+ P +L+ T
Sbjct: 245 ----------GGDAFPWVSPVIITLLVSSVLILFAFYWVEKNIAVEPIAPVEILSQPT 292
>YKR105c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 582
Score = 61.6 bits (148), Expect = 2e-09
Identities = 74/345 (21%), Positives = 132/345 (37%), Gaps = 31/345 (8%)
Query: 3 GSYFWLFAISIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFI 62
G +L S+ L FI ALD + F +S L S+ A+
Sbjct: 33 GLSLYLCLASLTLVLFITALDILIVGTIIDVVAEQFGNYSKTGWLVTGYSLPNAILSLIW 92
Query: 63 AKISDISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVAD 122
+ + I + + ++++ G +I A + ++ + G V +G SGL + ++
Sbjct: 93 GRFASIIGFQHSLILAILIFEAGSLIAALASSMNMLIFGRVVAGVGGSGLQTLCFVIGCT 152
Query: 123 MTKLKWRSLFTSFLSVPYLVTTW----ISGYLTQHFISTNWRWGYGMFAILTPAVLTPAI 178
M + R L S LS + V I G T H WRW F I P +
Sbjct: 153 MVGERSRPLVISILSCAFAVAAIVGPIIGGAFTTH---VTWRW---CFYINLP--IGGLA 204
Query: 179 IMISWLDRKANKSG---ETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGL 235
I++ L KA G + + ++ + +++ R L+ G + + D FG
Sbjct: 205 IIMFLLTYKAENKGILQQIKDAIGTISSFTFSKFRHQVNFKR----LMNGIIFKFDFFGF 260
Query: 236 VLLGFAFSLMLIPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIW-FAPF------ 288
L L L+ + WN+ +I V+G +L I VY+ + F F
Sbjct: 261 ALCSAGLVLFLLGLTFGGNKYS-WNSGQVITYLVLGVLLFIFSLVYDFFLFDKFNPEPDN 319
Query: 289 ----PLLPKRVLTNRTFICCVIIDFIYQMGGYFSLLYFTSYTSVV 329
PLL +R++ I ++ F+ G ++Y + ++
Sbjct: 320 ISYRPLLLRRLVAKPAIIIVNMVTFLLCTGYNGQMIYSVQFFQLI 364
>SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 599
Score = 59.3 bits (142), Expect = 8e-09
Identities = 65/321 (20%), Positives = 120/321 (37%), Gaps = 48/321 (14%)
Query: 12 SIFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISSR 71
++ LT F+ ALD T + P FN S S + A + P + +I R
Sbjct: 101 ALILTLFLAALDNTIVTTALPTIAEDFNDTSSSSWIGSAYVLASNAVLPAVGVFCNILGR 160
Query: 72 PTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRSL 131
+ + +++G + S + ++ +G G+ + +I+++D+T L+ R +
Sbjct: 161 KIVLYICIFFFMLGSALCGASQNMIWLIVCRAIQGLGGGGIISLVNIIISDITPLRTRPM 220
Query: 132 FTSFLSVPY----LVTTWISGYLTQHFISTNWRWGYGMFAILTPA--VLTPAIIMISWLD 185
++ L+ + + I G + Q T WRW +F I P+ + T I++ L
Sbjct: 221 YSGILATAWGAALVAGPIIGGAICQR---TTWRW---IFFINLPSGGIATALIVVFLHL- 273
Query: 186 RKANKSGETPIGVDPLAEKKRLIKQSEIDGLRAWLILLKGALIEIDAFGLVLLGFAFSLM 245
L K L D GLV + L+
Sbjct: 274 ------------------------------LPCERTSFKKFLKTFDFIGLVCVITGIVLI 303
Query: 246 LIPCSLYSYAVGGWNNPSMIAMEVVGGILLICYAVYEIWFAPFPLLPKRVLTNRT----F 301
L+ SL + G W +++ ++GG L + +Y+ + +LP NR+
Sbjct: 304 LLGISL-GASSGKWRRANILCYLIIGGCLFVFAFIYDTFTKRNAVLPPPFFKNRSSAALL 362
Query: 302 ICCVIIDFIYQMGGYFSLLYF 322
C Y + Y+ YF
Sbjct: 363 ACSSFFYLNYMLFAYYVPQYF 383
>SPAC1399.02 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 589
Score = 55.5 bits (132), Expect = 1e-07
Identities = 42/168 (25%), Positives = 77/168 (45%), Gaps = 1/168 (0%)
Query: 13 IFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISSRP 72
+ L+ F+ ALD T + P ++ + S S + A S+ PF +S++ R
Sbjct: 96 LMLSIFLAALDQTVITTAIPTIVANLDGGSSYSWIGTAYSLAETSILPFCGIMSEVVGRK 155
Query: 73 TTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRSLF 132
+VL++ G + + + V+ IG G+ + +IV+AD+T L+ R +
Sbjct: 156 IVLYTSIVLFLFGSAMCGAAQNMLWLVLCRAVQGIGGGGIMSLVTIVIADITPLQTRPYY 215
Query: 133 TSFLSVPYLVTTWISGYLTQHFISTNWRWGYGMFAILTPAVLTPAIIM 180
T + V + V + + G L IS N W + F L L+ A+++
Sbjct: 216 TGCMGVTWGVAS-VMGPLIGGAISQNTTWRWIFFINLPTGGLSLALLI 262
>CE25762 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 448
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/191 (25%), Positives = 81/191 (41%), Gaps = 26/191 (13%)
Query: 55 GAVCQPFIAKISDISSRPTTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSL 114
G + PF++++SDI R + + L + V +I A +P +++ + + S+
Sbjct: 128 GMIVSPFVSQLSDILGRRPLFLIPLYISVAANLICAAAPNYLIFLLFRFISGVATTSFSM 187
Query: 115 MNSIVVADMTKLKWRSLFTSFLSVPYLVT-TWISGYLTQ---HFISTNWRWGYGMFAILT 170
++ + L++RSL +P L T +W+ GY+ + NWR Y FA
Sbjct: 188 TGFVLCMESVSLEFRSL------IPVLTTISWVGGYMLAGVFYVFFKNWRVLY--FAASV 239
Query: 171 PAVLTPAIIMISWLDRKANKSGETPIGVDPLAEKK--RLIKQSEIDGLRAWLILLKGALI 228
P +LT I W TP + L K+ R IK+ + G L L L
Sbjct: 240 PGLLT---IPFFWF---------TPESLHWLMTKQNDRKIKKIVMSGTYWALSLYSTELS 287
Query: 229 EIDAFGLVLLG 239
E + G L G
Sbjct: 288 EDETTGYFLSG 298
>SPAC3H1.06c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 589
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/153 (23%), Positives = 71/153 (45%), Gaps = 7/153 (4%)
Query: 13 IFLTSFILALDATTTYSYQPYATSSFNRHSMVSTLTIANSVIGAVCQPFIAKISDISSRP 72
+ L+ F+ ALD T + P ++ + S S + A ++ PF +S++ R
Sbjct: 96 LMLSIFLSALDQTVITTAIPTIVANLDGGSSYSWIGTAYTLAQTSILPFCGIMSEVVGRK 155
Query: 73 TTYAVVLVLYVIGFIITACSPTIAAYVIGSVFIAIGQSGLSLMNSIVVADMTKLKWRSLF 132
+VL++ G + + + V+ IG G++ + +IV+AD+T L+ R +
Sbjct: 156 IVLYTSIVLFLFGSAMCGAAQNMLWLVLCRAVQGIGGGGITSLVTIVIADITPLQTRPYY 215
Query: 133 TSFLSVPY----LVTTWISGYLTQHFISTNWRW 161
T + V + ++ I G ++Q +WRW
Sbjct: 216 TGCMGVTWGLASVMGPLIGGAISQ---KASWRW 245
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.328 0.141 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,463,828
Number of Sequences: 60738
Number of extensions: 731039
Number of successful extensions: 2461
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2423
Number of HSP's gapped (non-prelim): 26
length of query: 336
length of database: 30,389,216
effective HSP length: 107
effective length of query: 229
effective length of database: 23,890,250
effective search space: 5470867250
effective search space used: 5470867250
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)