ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0057 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0057 14519 16135 539
(539 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 393 e-109
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 357 3e-98
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 350 2e-96
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 155 1e-37
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 151 3e-36
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 148 2e-35
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 134 5e-31
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 132 1e-30
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 102 1e-21
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 82 2e-15
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 76 1e-13
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 69 2e-11
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 67 7e-11
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 393 bits (1009), Expect = e-109
Identities = 197/437 (45%), Positives = 277/437 (63%), Gaps = 11/437 (2%)
Query: 113 SKGDFNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGSIFSWAIIVGLTGICNNYGSLM 172
+ +NNLN++FY GY++ Q+P H +MQ PLGK++ FSW++IV L NYG L+
Sbjct: 135 TSNQYNNLNTLFYVGYIVGQFPGHYIMQTFPLGKFVGLVTFSWSVIVFLHCCAYNYGGLI 194
Query: 173 ACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWAATAAAPLLSSFISFGLMHTNT 232
A RFFLG TE+ ++PA E T+GMF T +++ +QPVFW + + + + FI++GL
Sbjct: 195 ALRFFLGFTESCLLPAMEATMGMFFTHQEQAFLQPVFWISCLSCGIPAGFIAYGLEFVTK 254
Query: 233 STYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLSTKEKVYLIKQVQRSTESSIEQK 292
S PW++FM I G YPDNP+ A+FL+ +EK+Y I +V++ST IE K
Sbjct: 255 SIAPWKLFMIITGGITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTRGGIENK 314
Query: 293 TIKKYQIYETFKDPVSWLFFFQSFTLMLSNSLTYQQNQLYVDIGVDNLGSSLVSAAGSVW 352
KK+Q E KDP++WLF F +FTLMLSN+L YQQN ++ + V +L S+LV A + +
Sbjct: 315 IFKKHQFIEALKDPITWLFTFAAFTLMLSNNLAYQQNLIFTSLNVSDLNSTLVGVALAGY 374
Query: 353 DILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVTIDWSNKYALLACMILAGSSKG 412
+ + +I F + PNQS Y A ++ I IA V + WSN+ LA MI+A S G
Sbjct: 375 NTVSAIIATFAMYLIPNQSAYHAMFWMLPSITGGIAFVALPWSNRIGELATMIIA-SDFG 433
Query: 413 ITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAANIISPQLWNPKDAPRYYPSWIIQIVV 472
ITYIIALGWTT+++ GYTKKL R +MFM+ Y ANIISPQLW +DAPRYYP+WI+QIVV
Sbjct: 434 ITYIIALGWTTATSTGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVV 493
Query: 473 SFFLNIVILLTIRYILAKRNKERYQWVQEHPEDNF----------GIVSFTEGVNERVNL 522
++F+ +I L R ILA+RNK+R + + + + F V ++
Sbjct: 494 AWFVTPIIYLVARVILARRNKQRKELKDKKIAEGSLETIEKTYVDTVDEFGNPVKVLIDN 553
Query: 523 AMLDLTDFENKRFIYPL 539
+MLDLTD EN F+YPL
Sbjct: 554 SMLDLTDMENLNFVYPL 570
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 357 bits (915), Expect = 3e-98
Identities = 183/453 (40%), Positives = 273/453 (59%), Gaps = 6/453 (1%)
Query: 92 FMDKSXXXXXXXXXXXXXXXXSKGDFNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGS 151
++DK+ + +N++N++FY G++I Q P H+L+Q+ P+ K++A S
Sbjct: 101 YIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGHMLLQRFPVSKFVAAS 160
Query: 152 IFSWAIIVGLTGICNNYGSLMACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWA 211
W II+ L N+ LMA RFFLG E+ ++P E T+GMF ++ ++QP F+
Sbjct: 161 TALWTIIIFLHCAAYNFSGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYI 220
Query: 212 ATAAAPLLSSFISFGLMHTNTSTYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLST 271
+ + + FI++G+ + + PW++FM I G YPDN + A+FL+
Sbjct: 221 SCYGCNIPAGFIAYGVQYAKNTISPWKLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTK 280
Query: 272 KEKVYLIKQVQRSTESSIEQKTIKKYQIYETFKDPVSWLFFFQSFTLMLSNSLTYQQNQL 331
KE++Y + +V+RS S IE KT KKYQ+ E KDPV+WLF F F LSN+L YQQN L
Sbjct: 281 KERLYTVDRVRRSNHSGIESKTFKKYQVIEALKDPVTWLFTFHVFCNQLSNNLAYQQNLL 340
Query: 332 YVDIGVDNLGSSLVSAAGSVWDILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVT 391
+ + V +L S+LV A + ++ + +I +++ NQS + A I IA IA V
Sbjct: 341 FTSLNVSDLNSTLVGVASAGYNCVSAIIATYMMSVIKNQSAFHGAIWYIPSIAGGIACVA 400
Query: 392 IDWSNKYALLACMILAGSSKGITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAANIISP 451
+ W +K LA +I+A S+ GI +II+LGWTT+S AGYTKKL R VMFM+ Y ANII P
Sbjct: 401 MSWDHKIGELAAIIIA-SNFGIPFIISLGWTTASCAGYTKKLTRGVMFMIGYAIANIIGP 459
Query: 452 QLWNPKDAPRYYPSWIIQIVVSFFLNIVILLTIRYILAKRNKERYQWVQEHPEDN----- 506
Q+W +DAPRYYP+WI+QIV+++ ++ +LL IR+IL +RNK+R ++++ E
Sbjct: 460 QMWQSRDAPRYYPAWIVQIVIAWSVSPFVLLIIRWILVRRNKKRLALLEQNKEQYEKTWI 519
Query: 507 FGIVSFTEGVNERVNLAMLDLTDFENKRFIYPL 539
I S V+ +MLDLTD EN FIYPL
Sbjct: 520 ETIDSSGNHVSGFYENSMLDLTDQENLSFIYPL 552
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 350 bits (899), Expect = 2e-96
Identities = 193/502 (38%), Positives = 281/502 (55%), Gaps = 13/502 (2%)
Query: 51 LKFMDKYESTVEPLTXXXXXXXXXXNFXXXXXXXXXXXXXXFMDKSXXXXXXXXXXXXXX 110
L FM++ ++ V +T F +MDK+
Sbjct: 30 LAFMEENDAAVPEITPEQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDT 89
Query: 111 XXSKGDFNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGSIFSWAIIVGLTGICNNYGS 170
++ +N +N++FY G+ I Q+P L QKLPLGK+L G + +W I++ L+ N+
Sbjct: 90 GLTQNTYNTVNTLFYVGFAIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSG 149
Query: 171 LMACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWAATAAAPLLSSFISFGLMH- 229
++A RFFLG TE+VV+P T+GMF +R QP F+AA +P+ + FI++G++H
Sbjct: 150 VVALRFFLGLTESVVIPILITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHI 209
Query: 230 TNTSTYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLSTKEKVYLIKQVQRSTESSI 289
TN S W+IF I G +P+NPA+ KF S +E+V++I++VQ ST SSI
Sbjct: 210 TNPSISLWKIFTIIIGGLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSI 269
Query: 290 EQKTIKKYQIYETFKDPVSWLFFFQSFTLMLSNSLTYQQNQLYVDIG-VDNLGSSLVSAA 348
EQK KK Q E KD ++WLF L+N+L YQQN L+ +G VD LGS+LVS A
Sbjct: 270 EQKVFKKSQFREAMKDYITWLFGLFFLLQQLANNLPYQQNLLFEGMGGVDALGSTLVSVA 329
Query: 349 GSVWDILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVTIDWSNKYALLACMILAG 408
G+ + ++ I ++ + N S A + + SIA + W NK +LA + +AG
Sbjct: 330 GAGFAVVCAFIATLMLAKWKNISALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAG 389
Query: 409 SSKGITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAANIISPQLWNPKDAPRYYPSWII 468
GI +IIAL W +SSA+GYTKKL R+ + + A G ANIISPQ+W KD+PR+ P+WI+
Sbjct: 390 QIFGIPFIIALSWASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIV 449
Query: 469 QIVVSFFLNIVILLTIRYILAKRNKERYQWVQEHPEDNFGIVSFTEG-----------VN 517
QIV+SF L ILL I +IL +RN +R + E+ ++ + E V
Sbjct: 450 QIVLSFSLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDRIQLIESENPSSIEEGKVVT 509
Query: 518 ERVNLAMLDLTDFENKRFIYPL 539
NLA+ DLTD EN+ FIYPL
Sbjct: 510 HENNLAVFDLTDLENETFIYPL 531
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 155 bits (393), Expect = 1e-37
Identities = 118/450 (26%), Positives = 196/450 (43%), Gaps = 22/450 (4%)
Query: 92 FMDKSXXXXXXXXXXXXXXXXSKGDFNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGS 151
++DK+ ++++ ++FYAGYL+AQ+P ILMQK L ++ +
Sbjct: 89 YLDKTALSYAALYGMKTDTHIDGHTYSSMTTLFYAGYLVAQYPAAILMQKCRLSYFIFCN 148
Query: 152 IFSWAIIVGLTGICNNYGSLMACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWA 211
+F W+ +V L C N SL+ RF G EA + PA M+ E++ + ++A
Sbjct: 149 VFLWSAMVCLMAACRNGPSLLGLRFLAGIFEASITPAFINITAMWYRREEQPMRTLCWYA 208
Query: 212 ATAAAPLLSSFISFGLMHTNTSTYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLST 271
A ++ S +S+GL H + WR ++ I G P NP+ A+FLS+
Sbjct: 209 FNGIAQIIGSILSYGLGHIHGKVASWR-YVFIVIGLMSLGWGVVFVFIPSNPSKARFLSS 267
Query: 272 KEKVYLIKQVQRSTESSIEQKTIKKYQIYETFKDPVSWLFFFQSFTLMLSNSLTYQQNQL 331
+EK +++V R + +E K K YE F DP + + M++N + +
Sbjct: 268 REKRIALERV-RDNRTGLENKQFKWKHAYEAFLDPQVIMITLFTGVCMITNGIGVFSTLI 326
Query: 332 YVDIGVDNLGSSLVSAAGSVWDILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVT 391
+G + L S++++ ++ I + + N I L +A + +
Sbjct: 327 IKGLGYNELHSAVLNMPLGAIEVAAMFISGVLCKVFKNGRLLIGVFMNCLTLAGCLMIWK 386
Query: 392 IDWSNKYALLA----CMILAGSSKGITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAAN 447
I SN Y L M + SS + L +S+ AGYTKK + + Y N
Sbjct: 387 IPDSNPYGRLVGVWFTMWVPASS-----ALLLSLISSNVAGYTKKTVTSATVFVFYSVGN 441
Query: 448 IISPQLWNPKDAPRYYPSWIIQIVVSFFLNIVILLTIRYILAKRNKERYQWVQEHPEDNF 507
I+SPQL+ P Y I ++VS + I I + NK R + + E P
Sbjct: 442 IVSPQLFKSGQTPEYIEG-IQAMIVSLCIIIAIAFVLTGYYIYENKRRDRLLAEDP---- 496
Query: 508 GIVSFTEGVNERVNLAMLDLTDFENKRFIY 537
S E + N +DLTD + +F Y
Sbjct: 497 ---SLGESIK---NEEFMDLTDRQQPKFRY 520
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 151 bits (381), Expect = 3e-36
Identities = 115/427 (26%), Positives = 198/427 (45%), Gaps = 26/427 (6%)
Query: 116 DFNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGSIFSWAIIVGLTGICNNYGSLMACR 175
+F+NL +IF A Y+ + L+QK P+ K L I W I++ C Y SLM R
Sbjct: 116 EFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAACKTYASLMVVR 175
Query: 176 FFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWAATAAAP-LLSSFISFGLMHTN-TS 233
LG E+ C GM+ T ++ + FWA A ++ ISFG +H + T+
Sbjct: 176 TLLGLFESSSAVGCIAISGMYYTKSEQS-ARIGFWATQAGTGYIVGGLISFGFLHYHGTA 234
Query: 234 TYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLSTKEKVYLIKQVQRSTESSIEQKT 293
W+I + PDN NA FL+ +EK+ +++ + R+ ++ +E K
Sbjct: 235 FTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVEHI-RANQTGLETKK 293
Query: 294 IKKYQIYETF-KDPVSW-LFFFQSFTLMLSNSLTYQQNQLYVDIGVDNLGSSLVSAAGSV 351
KK Q+ E F D +W + + + + + ++ + G D ++L+
Sbjct: 294 FKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYETALLQLPIGA 353
Query: 352 WDILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVTIDWSNKYA-LLACMILAGSS 410
++ LI ++ + + + I I I I ++++ S+K L + +L S
Sbjct: 354 ITAMIILITTQMLSRWGHIT-LITTSMYIPAIIGCIVLISLPLSHKIGNLFSLYLLYSGS 412
Query: 411 KGITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAANIISPQLWNPKDAPRYYPSWIIQI 470
IT I W + + +GYTK+++RN + M+ Y + II+PQ++ APRY P+ I +
Sbjct: 413 CVITNIYI--WNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPA-KIAL 469
Query: 471 VVSFFLNIVILLTIRYILAKRNKERYQWVQEHPEDNFGIVSFTEGVNERVNLAMLDLTDF 530
+V+ + + + L I YI K N++R + + ER LDLTD
Sbjct: 470 LVTQCVCVPLQLYIGYICKKENEKRDK---------------EQEGQERKKYQFLDLTDI 514
Query: 531 ENKRFIY 537
EN+ F Y
Sbjct: 515 ENRNFRY 521
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 148 bits (374), Expect = 2e-35
Identities = 120/453 (26%), Positives = 201/453 (43%), Gaps = 24/453 (5%)
Query: 92 FMDKSXXXXXXXXXXXXXXXXSKGDFNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGS 151
+MDKS +N + + FY G+++ P L+QK PL K +
Sbjct: 64 YMDKSTSNYSSIMGIRTDLNMVGNQYNWVGTSFYLGFMVFSLPLSTLLQKFPLSKVTSAF 123
Query: 152 IFSWAIIVGLTGICNNYGSLMACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWA 211
I +W I++ LT + ++Y S +A R LG E+V+ PA + + + E++ A
Sbjct: 124 IVAWGILMTLTCLVHSYASYIATRTLLGILESVITPAFVLFIAQWYRKEEQFFRMAFLVA 183
Query: 212 ATAAAPLLSSFISFGL----MHTNTSTYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAK 267
L+ +S+GL + N + PWRI I PD P+ A
Sbjct: 184 WNGLGGLIGGSMSYGLYKRELENNLTMSPWRILFIITGLITIINGVFIFIHIPDEPSKAW 243
Query: 268 FLSTKEKVYLIKQVQRSTESSIEQKTIKKYQIYETFKDPVSWLFFFQSFTLMLSN-SLTY 326
FLS KEK ++K++ + + + K KKYQI E +D +L+FF + + N L+
Sbjct: 244 FLSEKEKDLVLKRLD-TDHAGLGSKKFKKYQILEACRDVRMYLYFFLQIAVAIPNGGLSN 302
Query: 327 QQNQLYVDIGVDNLGSSLVSAAGSVWDILLYLIFAFVILNYPNQSGYIAAGCLILPIASS 386
+ + ++G + L++ S +F +I + N+ IA L + + S
Sbjct: 303 FSSIMLKNLGYVKGKALLMNMPTSSISFAALTLFG-LIPEFTNRRMDIALVGLAINLTSG 361
Query: 387 IAMVTIDWSNKYALLACMILAGSSKGITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAA 446
+ +A LA L G S I YI L +S++AG+TKK++ + + M+ Y
Sbjct: 362 SLIAFA--KPTHAQLAGYWLFGISP-IPYICILSCISSNSAGHTKKVFMSAVSMIGYCVG 418
Query: 447 NIISPQLWNPKDAPRYYPSWIIQIVVSFFLNIVILLTIRYILAKRNKERYQWVQEHPEDN 506
N++ PQ + AP+Y + + VV + + I I++ I + + N+ R E N
Sbjct: 419 NMVGPQTFRSTQAPKYQGA-KVSFVVCYCVAIFIIIAIYAVNVRENRRR-------DEKN 470
Query: 507 FGIVSFTEGVNERVNLAMLDLTDFENKRFIYPL 539
+ NE DLTDFEN F Y +
Sbjct: 471 EYL------SNELSEEDKKDLTDFENPEFRYSI 497
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 134 bits (336), Expect = 5e-31
Identities = 108/423 (25%), Positives = 185/423 (43%), Gaps = 30/423 (7%)
Query: 124 FYAGYLIAQWPCHILMQKLPLGKYLAGSIFSWAIIVGLTGICNNYGSLMACRFFLGATEA 183
FY GYL+ ++P +L+Q+ PL K L + W ++ +T + N Y +A R LG E+
Sbjct: 109 FYLGYLVFEFPASLLLQRFPLSKTLCVFLVIWGFLLCMTSVAN-YPGFIALRVLLGMMES 167
Query: 184 VVVPACEITLGMFLTTEQREIVQPVFWAATAAAPLLSSFISFGLM-HTNTSTYPWRIFMA 242
P + + ++++ V+ A +L S +++GL T+ W++
Sbjct: 168 AASPGFILLTAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAKRTSLPMRGWKLIFI 227
Query: 243 INAGXXXXXXXXXXXXYPDNPANAKFLSTKEKVYLIKQVQRSTESSIEQKTIKKYQIYET 302
I PDNP A FL+ +++ ++K++ R+ + + K YQ ET
Sbjct: 228 ICGVLAIFLGFVILAVVPDNPFKAWFLTEEDRKLVVKRL-RANKQGVGNNHFKLYQFKET 286
Query: 303 FKDPVSWLFFFQSFTLMLSNSL--TYQQNQLYVDIGVDNLGSSLVSAAGSVWDILLYLIF 360
D +W+ F S L + N T+ + +G D L + L+ + + F
Sbjct: 287 MLDIRTWIMFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAF 346
Query: 361 AFVILNYPNQSGYIAAGCLILPIASSIAMV---TIDWSNK-YALLACMILAGSSKGITYI 416
F+ L +I ++ I + IA++ + ++ A LA L S G I
Sbjct: 347 GFLSL-------FIHKRMVLATITTCIALIGSCLLSFAGPPRAQLAGYYLLMVSPG-AMI 398
Query: 417 IALGWTTSSAAGYTKKLYRNVMFMLAYGAANIISPQLWNPKDAPRYYPSWIIQIVVSFFL 476
+ +S+A+GYTKK+ V++++ Y N+I PQ + DAP Y P+ +V +
Sbjct: 399 VMFAIISSNASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPA-KNTMVGCYAA 457
Query: 477 NIVILLTIRYILAKRNKERYQWVQEHPEDNFGIVSFTEGVNERVNLAMLDLTDFENKRFI 536
+V + Y+ + NK R Q E + R N DLTDFEN F
Sbjct: 458 TLVTFPALYYVNWRENKRRDQLAAEGK------------IEHRPNAEFEDLTDFENLDFR 505
Query: 537 YPL 539
Y L
Sbjct: 506 YTL 508
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 132 bits (332), Expect = 1e-30
Identities = 118/462 (25%), Positives = 205/462 (43%), Gaps = 29/462 (6%)
Query: 92 FMDKSXXXXXXXXXXXXXXXXSKGDFNNLNSIFYAGYLIAQW-PCHILMQKLP-LGKYLA 149
FMDK ++ + S FY GYL P + Q+ + K LA
Sbjct: 97 FMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQRTSHMSKMLA 156
Query: 150 GSIFSWAIIVGLTGICN-NYGSLMACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPV 208
I W +++ L Y S + R LG E+VV P I + TE++ +
Sbjct: 157 VFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKTEEQFTRVSI 216
Query: 209 FWAATAAAPLLSSFISFGLMHTNTSTYP---WRIFMAINAGXXXXXXXXXXXXYPDNPAN 265
++ +L + I++G+ + + +Y WR I PD+P+
Sbjct: 217 WFGMNGLGSILINAIAYGV-YIHQDSYAIKGWRTLFVITGVITIFIGILIFLWIPDDPSK 275
Query: 266 AKFLSTKEKVYLIKQVQRSTESSIEQKTIKKYQIYETFKDPVSWLFFFQSFTLMLSNS-- 323
A+FLS +EK+ +++++ RS + IKKYQI E KD +WL+F + + + N
Sbjct: 276 ARFLSKREKLMVVQRI-RSNQQGFGNHEIKKYQIIEALKDVRTWLYFLFTVSSNIPNGGI 334
Query: 324 LTYQQNQLYVDIGVDNLGSSLVSAAGSVWDILLYLIFAFVILNYPNQS----GYIAAGCL 379
++ L D G + + L+ +++ +F + + N+ Y + +
Sbjct: 335 SSFMSILLNSDFGYSSKETLLMGLPTGAVELVGCPLFGILAVYAANKKIPFWKYKLSWAI 394
Query: 380 ILPIASSIA--MVTIDWSNKYALLACMILAGSSKGITYIIALGWTTSSAAGYTKKLYRNV 437
+ + IA M+ ++K A LA L S +++I L +++++GY+KK +
Sbjct: 395 FAAVLALIASCMLGFATNSKKARLAGAYLWYISP-VSFICVLSNISANSSGYSKKWTVSS 453
Query: 438 MFMLAYGAANIISPQLWNPKDAPRYYPSWIIQIVVSFFLNIVILLTIRYILAKRNKERYQ 497
+ ++AY AAN+ PQ + K AP+Y+ + + +VV + + IV+L + + + NK R +
Sbjct: 454 INLVAYAAANLAGPQTFIAKQAPKYHGA-KVAMVVCYAVMIVLLSILLIVNLRENKRRDK 512
Query: 498 WVQEHPEDNFGIVSFTEGVNERVNLAMLDLTDFENKRFIYPL 539
E F E E NL DLTDFEN F Y L
Sbjct: 513 IAAER--------GFPE---ETENLEFSDLTDFENPNFRYTL 543
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 102 bits (255), Expect = 1e-21
Identities = 81/384 (21%), Positives = 168/384 (43%), Gaps = 10/384 (2%)
Query: 117 FNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGSIFSWAIIVGLTGICNNYGSLMACRF 176
+N + SIFY +++ +P L ++ + L + S+ + N+G +MA R+
Sbjct: 98 YNIMISIFYIPFVLCAFPFSYLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMAVRW 157
Query: 177 FLGATEAVVVPACEITLGMFLTTEQREIVQPVFWAATAAAPLLSSFISFGLMHTNTSTYP 236
FLG E+ V+P L F + +F+AA + +++G+ H
Sbjct: 158 FLGMAESAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIKGGKLQ 217
Query: 237 -WRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLSTKEKVYLIKQVQRSTESSIEQKTIK 295
W+ I G P + A FL+ +EK +++ + S+I +K
Sbjct: 218 GWQYLFLIEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAISEKLSF 277
Query: 296 KYQIYETFKDPVSWLFFFQSFTLMLS-NSLTYQQNQLYVDIGVDNLGSSLVSAAGSVWDI 354
K Q FK P++ L+ + L + NS+ Q+ +G ++ ++L++ A ++
Sbjct: 278 K-QSLTVFKHPIAILWLLEEMALGVPLNSINNWLPQIVAAMGFSSVNTNLMTVAPAISGA 336
Query: 355 LLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVTIDWSNKYAL--LACMILAGSSKG 412
+ L+FAF I ++ G + + + I +ID N + AC ++ +
Sbjct: 337 IWLLVFAF-ISDFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTAGAAA 395
Query: 413 ITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAANIISPQLWNPKDAPRYYPSWIIQIVV 472
+ + + + ++ + ++ +V LA ++S ++ P+DAP+Y P+ + I
Sbjct: 396 SSVLTSTWYNNNTPNESRRAVFTSVGVPLA-NVMGLVSANIFRPQDAPKYVPA--LGITA 452
Query: 473 SF-FLNIVILLTIRYILAKRNKER 495
F L I+++ +I + N+ R
Sbjct: 453 GFGGLGILLVASISVYMFFDNRRR 476
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 82.0 bits (201), Expect = 2e-15
Identities = 77/413 (18%), Positives = 169/413 (40%), Gaps = 21/413 (5%)
Query: 92 FMDKSXXXXXXXXXXXXXXXXSKGDFNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGS 151
F+D+S N SIFY Y++ + P +L++++ + LA
Sbjct: 73 FLDRSNIGNAAVAGMTEALSLYGERLNVAVSIFYVLYILVETPSVVLVKRIKASRMLAFI 132
Query: 152 IFSWAIIVGLTGICNNYGSLMACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWA 211
F+W++ V +G ++YG L+A R LG E + PA + L T +++ +A
Sbjct: 133 SFAWSMTVLFSGFMSSYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQCQRLSYLFA 192
Query: 212 ATAAAPLLSSFISFGLMHTNTSTYP-WRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLS 270
+ A ++ L + W+ + PD NA FL+
Sbjct: 193 SAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEGLVSFIGVPLCLFALPDKMENAWFLT 252
Query: 271 TKEKVYLIKQVQRSTESSIE-QKTIKKYQIYETFKDPVSWLFFFQSFTL-MLSNSLTYQQ 328
+E+ I ++R + ++ + ++ + FKDP ++ F M+ +
Sbjct: 253 REEREVAI--IRRDINARYHGEQHFEWSEVRKAFKDPKVYVSATSQFCADMVLYGFSSFL 310
Query: 329 NQLYVDIGVDNLGSSLVSAAGSVWDILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIA 388
+ +G L ++ ++ + ++ +L A++ ++ Y+ + ++ + I
Sbjct: 311 PVIIKGLGFVGLQTNYMTIPVYIAGVISFLFVAWLSDRTQLRAVYLISASTVVAVGYIIM 370
Query: 389 MVTIDWSNKYA-----LLACMILAGSSKGITYIIALGWTTSSAAGYTKKLYRNVMFMLAY 443
+ + + KY + C I G + LGW ++ AG+ K+ +
Sbjct: 371 LASDSNAAKYTATYIIAIGCYIGPG--------LNLGWLNNNVAGHYKRATAIGIQQTLA 422
Query: 444 GAANIISPQLWNPKDAPRYYPSWIIQ---IVVSFFLNIVILLTIRYILAKRNK 493
++ I++ Q++ K+AP+Y ++V +V+ ++RY+ KR++
Sbjct: 423 NSSGIVAGQIYRSKNAPKYILGNAFTLGCVIVGGLAYVVMFFSLRYVNKKRDE 475
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 75.9 bits (185), Expect = 1e-13
Identities = 87/409 (21%), Positives = 174/409 (42%), Gaps = 56/409 (13%)
Query: 114 KGD-FNNLNSIFYAGYLIAQWPCHILMQKLPLGKYLAGSIFSWAIIVGLTGICNNYGSLM 172
KGD FN + S+FY +++ + P +LM+K+ + LA + S+++ TG C+N+G L+
Sbjct: 92 KGDQFNIIASVFYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFTGFCHNFGGLL 151
Query: 173 ACRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWAATAAAPLLSSFISFGLMHTN- 231
A R LG EA + P + L M + + +A++A + ++ ++H +
Sbjct: 152 AARLVLGFCEAGLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGGLFAYAVLHMDG 211
Query: 232 -TSTYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLS-TKEKVYLIKQVQRSTE--- 286
WR I P++ A FLS T +++ +Q++R+ +
Sbjct: 212 VGGFAGWRWLFIIEGLIGFVCGVAVYFIIPNDITKAWFLSKTHQEMMRKRQLERAADLEA 271
Query: 287 SSIEQKTIKK---------YQIYETFKDPVSWLFFFQSFTLMLSNSLTYQQNQL-YVDIG 336
+ + K +K Y + E +D + L+ F +F + + + Y + Y+ I
Sbjct: 272 AHFDWKGVKSAFTDFKVYLYALSEFGQD--TCLYGFSTFLPAIISGMGYTSLSVQYMTIP 329
Query: 337 VDNLGSSLVSAAGSVWDILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVTIDWSN 396
V LG++ AA + D + +I N I PI I ++ +
Sbjct: 330 VYILGAATYIAASFLSDRFHHRGIILIIGN-------------IFPIVGYILLLACQNNK 376
Query: 397 KYALLACM-----ILAGSSKGITYIIALGWTTSSAAGYTKKLYRNVMFMLAYGAANIISP 451
AC + G+ +T W +++ A + K+ + + ++ I++
Sbjct: 377 SVLYFACYLCSVGVYTGAGLNVT------WLSANIAPHYKRATAISLQLAIANSSGILAG 430
Query: 452 QLWNPKDAPRYYPSWI-------IQIVVSFFLNIVILLTIRYILAKRNK 493
Q++ RY P +I I I +S L++V + +++ +K+ K
Sbjct: 431 QIY------RYPPKYIAGHLTSLIAIFISTVLHVVNIFFLKHQNSKKQK 473
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 68.6 bits (166), Expect = 2e-11
Identities = 70/304 (23%), Positives = 122/304 (40%), Gaps = 31/304 (10%)
Query: 122 SIFYAGYLIAQWPCHILMQKLPLGKYLAGSIFSWAIIVGLTGICNNYGSLMACRFFLGAT 181
S+FYA Y+ A+ P +L++K YL+ I W+++ T +Y SL+ R LG
Sbjct: 86 SVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLGIC 145
Query: 182 EAVVVPACEITLGMFLTTEQREIVQPVFWAATAAAPLLSSFISFGLMH-TNTSTYP-WRI 239
E P + + M E++ + + + I+ GL +S P W
Sbjct: 146 EGGFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNWGW 205
Query: 240 FMAINAGXXXXXXXXXXXXYPDNPANAKFLSTKEKVYLIKQVQRSTESSIEQKTIKKYQI 299
I PD+P+ A+FL+ +EK L+K + + Q
Sbjct: 206 LYIIEGLISAISALWILFCLPDDPSTARFLNPREK-ELMKIRAEQRQKYMGSPNFDWTQF 264
Query: 300 YETFKDPVSWLFFFQSF--TLMLSNSLTYQQNQLYVDIGVDNLGSSLVS----AAGSV-- 351
+ FKDP ++ F L+L T+ + L +++G +L + +S A G +
Sbjct: 265 RKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGISV 324
Query: 352 --------------WDIL---LYLIFAFVILNYPNQS--GYIAAGCLILPIASSIAMVTI 392
W I+ + + F+IL S Y+A + LP+ ++A+ I
Sbjct: 325 YVICLLSDRTNIRGWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVAL-NI 383
Query: 393 DWSN 396
W N
Sbjct: 384 TWIN 387
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 67.0 bits (162), Expect = 7e-11
Identities = 77/387 (19%), Positives = 156/387 (39%), Gaps = 21/387 (5%)
Query: 117 FNNLNSIFYAGYLIAQWPCHILMQKL---PLGKYLAGSIFSWAIIVGLTGICNNYGSLMA 173
+N ++F+A Y++ P + K+ PL + + F AI +G T NY L+
Sbjct: 129 YNTCVTVFFATYVLFD-PIGTNLLKIMGPPLMMSICLTCFG-AISLG-TAWVKNYAQLIV 185
Query: 174 CRFFLGATEAVVVPACEITLGMFLTTEQREIVQPVFWAATAAAPLLSSFISFGLMHTNTS 233
R LGA E ++ PA + L + EQ + ++A + I++G + S
Sbjct: 186 VRLLLGAFEGMIYPAINMYLSVCYRREQYALRFAFVFSAACLSSSFGGLIAYGCSKISGS 245
Query: 234 TYPWRIFMAINAGXXXXXXXXXXXXYPDNPANAKFLSTKEKVYLIKQVQRSTESSIEQKT 293
W+ + N ++ F + +EK Y+ ++ + ++K
Sbjct: 246 LKDWQYIYIVEGCISLGFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEK- 304
Query: 294 IKKYQIYETFKDPVSWLFFFQSFTLMLSN-SLTYQQNQLYVDIGVDNLGSSLVSAAGSVW 352
+ +Q+++ KD +W F + L+ LT + +G N+ + L++
Sbjct: 305 FEWFQVWQAVKDVKTWASAVALFGIDLTTFGLTVFLPIIITSMGFTNVRAQLMTVPIYFL 364
Query: 353 DILLYLIFAFVILNYPNQSGYIAAGCLILPIASSIAMVTIDWSNKY--ALLACMILAGSS 410
+++ I A +S +I CL I +I + + +Y + CM
Sbjct: 365 TAIVFFICAVWSDRIKLRSPFILGACLTTSIGIAIVLGSQVHGVRYFGVYILCM------ 418
Query: 411 KGITYIIALG--WTTSSAAGYTKKLYRNVMFMLAYGAANIISPQLWNPKDAPRYYPSWII 468
GI A W + + Y K+ + + + ++S Q++ KD PRY +
Sbjct: 419 -GIYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKG--L 475
Query: 469 QIVVSFFLNIVILLTIRYILAKRNKER 495
I ++F + + + ++ L KR ++
Sbjct: 476 SISLAFQVFSIFMTVVQIFLYKRENDK 502
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,289,779
Number of Sequences: 60738
Number of extensions: 970322
Number of successful extensions: 2311
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2272
Number of HSP's gapped (non-prelim): 14
length of query: 539
length of database: 30,389,216
effective HSP length: 111
effective length of query: 428
effective length of database: 23,647,298
effective search space: 10121043544
effective search space used: 10121043544
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)