ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0119 good Q KOG0024 Secondary metabolites biosynthesis, transport and catabolism Sorbitol dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0119 37675 36521 -385
(385 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YAL060w [Q] KOG0024 Sorbitol dehydrogenase 482 e-136
YAL061w [Q] KOG0024 Sorbitol dehydrogenase 441 e-124
YDL246c [Q] KOG0024 Sorbitol dehydrogenase 128 2e-29
YJR159w [Q] KOG0024 Sorbitol dehydrogenase 127 2e-29
7299382 [Q] KOG0024 Sorbitol dehydrogenase 126 6e-29
7298873 [Q] KOG0024 Sorbitol dehydrogenase 124 3e-28
CE06215 [Q] KOG0024 Sorbitol dehydrogenase 121 2e-27
YLR070c [Q] KOG0024 Sorbitol dehydrogenase 119 6e-27
SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase 116 6e-26
CE06216 [Q] KOG0024 Sorbitol dehydrogenase 113 5e-25
At5g51970 [Q] KOG0024 Sorbitol dehydrogenase 105 9e-23
Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase 102 1e-21
Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase 91 2e-18
Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase 90 5e-18
SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III 75 1e-13
YDL168w [Q] KOG0022 Alcohol dehydrogenase class III 73 8e-13
At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V 72 1e-12
Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III 71 2e-12
Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III 71 3e-12
At5g43940 [Q] KOG0022 Alcohol dehydrogenase class III 68 3e-11
SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V 67 3e-11
Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III 67 4e-11
At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V 67 4e-11
CE20628 [Q] KOG0023 Alcohol dehydrogenase class V 66 8e-11
7299380 [Q] KOG0022 Alcohol dehydrogenase class III 66 8e-11
At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V 61 2e-09
SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III 61 3e-09
7300579 [Q] KOG0024 Sorbitol dehydrogenase 58 2e-08
CE12212 [Q] KOG0023 Alcohol dehydrogenase class V 58 3e-08
At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V 57 4e-08
At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V 56 8e-08
At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V 55 2e-07
YBR145w [Q] KOG0023 Alcohol dehydrogenase class V 52 1e-06
At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V 52 1e-06
YMR318c [Q] KOG0023 Alcohol dehydrogenase class V 52 2e-06
CE12214 [Q] KOG0023 Alcohol dehydrogenase class V 52 2e-06
YMR303c [Q] KOG0023 Alcohol dehydrogenase class V 50 6e-06
YOL086c [Q] KOG0023 Alcohol dehydrogenase class V 49 1e-05
>YAL060w [Q] KOG0024 Sorbitol dehydrogenase
Length = 382
Score = 482 bits (1240), Expect = e-136
Identities = 231/381 (60%), Positives = 284/381 (73%)
Query: 1 MRALAYFGKQDIRYTKDLEEPVIETDDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVH 60
MRALAYF K DI +T D+ P I+TDD + I+VSWCGICGSDLHEYLDGPIF P+DG+ H
Sbjct: 1 MRALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLHEYLDGPIFMPKDGECH 60
Query: 61 DVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXX 120
+S LP AMGHEMSGIVSKVGPKVT +K GDHVVV+A +C D + WP+
Sbjct: 61 KLSNAALPLAMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASSCADLHCWPHSKFYNSKPC 120
Query: 121 XXCQRGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWH 180
CQRG N C H GF+GLGV SGGFA +P +PLDVAALVEP+SV+WH
Sbjct: 121 DACQRGSENLCTHAGFVGLGVISGGFAEQVVVSQHHIIPVPKEIPLDVAALVEPLSVTWH 180
Query: 181 AVRISKLQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDP 240
AV+IS +KG SALVLGAGPIGL TIL L+G GASKIVVSE AE R A KLGVE F+P
Sbjct: 181 AVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAKKLGVEVFNP 240
Query: 241 SEHKEDAVNILKKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDF 300
S+H ++ IL+ L +GFD++YDCSG++ TF+T + A TF+G NIA+WG KP+ F
Sbjct: 241 SKHGHKSIEILRGLTKSHDGFDYSYDCSGIQVTFETSLKALTFKGTATNIAVWGPKPVPF 300
Query: 301 KPMDVTLQEKFVTGSMCYTIKDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDE 360
+PMDVTLQEK +TGS+ Y ++ FE+VV+A+ NG IA++ + LITG+Q+IEDG+ KGF E
Sbjct: 301 QPMDVTLQEKVMTGSIGYVVEAFEEVVRAIHNGDIAMEDCKQLITGKQRIEDGWEKGFQE 360
Query: 361 LMNHKEKNIKILLTPNNHGEL 381
LM+HKE N+KILLTPNNHGE+
Sbjct: 361 LMDHKESNVKILLTPNNHGEM 381
>YAL061w [Q] KOG0024 Sorbitol dehydrogenase
Length = 417
Score = 441 bits (1135), Expect = e-124
Identities = 206/383 (53%), Positives = 268/383 (69%), Gaps = 1/383 (0%)
Query: 1 MRALAYFGKQDIRYTKDLEEPVIETDDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVH 60
MRALAYFGK +IR+T L+EP I D + I++ WCGICG+DLHEY DGPIFFPEDG H
Sbjct: 1 MRALAYFGKGNIRFTNHLKEPHIVAPDELVIDIEWCGICGTDLHEYTDGPIFFPEDGHTH 60
Query: 61 DVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXX 120
++S LPQAMGHEM+G V +VGP V N+K GD VVVE TGTC D Y WP
Sbjct: 61 EISHNPLPQAMGHEMAGTVLEVGPGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEWC 120
Query: 121 XXCQRGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWH 180
C++G+YN C++LG G GV SGGFA +P+ +PLDVAAL++P++V WH
Sbjct: 121 AACKKGYYNICSYLGLCGAGVQSGGFAERVVMNESHCYKVPDFVPLDVAALIQPLAVCWH 180
Query: 181 AVRISKLQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDP 240
A+R+ + + G +AL++GAGPIGL TILAL G IVVSEPA++RR A K+G +DP
Sbjct: 181 AIRVCEFKAGSTALIIGAGPIGLGTILALNAAGCKDIVVSEPAKVRRELAEKMGARVYDP 240
Query: 241 SEH-KEDAVNILKKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPID 299
+ H +++++ L+ +A GG+GFD+ +DCSG++ T + + TFRG VN+A+WGH I
Sbjct: 241 TAHAAKESIDYLRSIADGGDGFDYTFDCSGLEVTLNAAIQCLTFRGTAVNLAMWGHHKIQ 300
Query: 300 FKPMDVTLQEKFVTGSMCYTIKDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFD 359
F PMD+TL E+ TGSMCYT DFE V++AL G I ID+ARH+ITGR IEDG
Sbjct: 301 FSPMDITLHERKYTGSMCYTHHDFEAVIEALEEGRIDIDRARHMITGRVNIEDGLDGAIM 360
Query: 360 ELMNHKEKNIKILLTPNNHGELD 382
+L+N KE IKI+LTPNNHGEL+
Sbjct: 361 KLINEKESTIKIILTPNNHGELN 383
>YDL246c [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 128 bits (321), Expect = 2e-29
Identities = 96/358 (26%), Positives = 156/358 (42%), Gaps = 34/358 (9%)
Query: 21 PVIETDDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVS 80
P I+ +++ + GICGSD+H Y G I GK L P +GHE SG V
Sbjct: 25 PTIKDPHYVKLAIKATGICGSDIHYYRSGGI-----GKYI----LKAPMVLGHESSGQVV 75
Query: 81 KVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLG 140
+VG VT +K GD V +E + G YN C H+ F
Sbjct: 76 EVGDAVTRVKVGDRVAIEP--------------GVPSRYSDETKEGSYNLCPHMAFAATP 121
Query: 141 VHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGP 200
G +P + + A VEP+SV H+ +++ ++ G +V GAGP
Sbjct: 122 PIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGP 181
Query: 201 IGLATILALQGHGASKIVVSEPAEIRRNQAAKLG-VETFDPSEHK----EDAVNILKKLA 255
+GL T + GA+ ++ + + + +A G TF+ S+ +D + ++KL
Sbjct: 182 VGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLL 241
Query: 256 PGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGS 315
GG D ++CSG D V T G V + + G +F +V+ +E + G
Sbjct: 242 -GGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGM-GKNYTNFPIAEVSGKEMKLIGC 299
Query: 316 MCYTIKDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDELMNHKEKNIKILL 373
Y+ D+ D V + G + + + LIT + K ED K +D + H + +K ++
Sbjct: 300 FRYSFGDYRDAVNLVATGKVNV---KPLITHKFKFEDA-AKAYDYNIAHGGEVVKTII 353
>YJR159w [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 127 bits (320), Expect = 2e-29
Identities = 96/358 (26%), Positives = 156/358 (42%), Gaps = 34/358 (9%)
Query: 21 PVIETDDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVS 80
P I+ +++ + GICGSD+H Y G I GK L P +GHE SG V
Sbjct: 25 PTIKDPHYVKLAIKATGICGSDIHYYRSGGI-----GKYI----LKAPMVLGHESSGQVV 75
Query: 81 KVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLG 140
+VG VT +K GD V +E + G YN C H+ F
Sbjct: 76 EVGDAVTRVKVGDRVAIEP--------------GVPSRYSDETKEGRYNLCPHMAFAATP 121
Query: 141 VHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGP 200
G +P + + A VEP+SV H+ +++ ++ G +V GAGP
Sbjct: 122 PIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGP 181
Query: 201 IGLATILALQGHGASKIVVSEPAEIRRNQAAKLG-VETFDPSEHK----EDAVNILKKLA 255
+GL T + GA+ ++ + + + +A G TF+ S+ +D + ++KL
Sbjct: 182 VGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLL 241
Query: 256 PGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGS 315
GG D ++CSG D V T G V + + G +F +V+ +E + G
Sbjct: 242 -GGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGM-GKNYTNFPIAEVSGKEMKLIGC 299
Query: 316 MCYTIKDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDELMNHKEKNIKILL 373
Y+ D+ D V + G + + + LIT + K ED K +D + H + +K ++
Sbjct: 300 FRYSFGDYRDAVNLVATGKVNV---KPLITHKFKFEDA-AKAYDYNIAHGGEVVKTII 353
>7299382 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 126 bits (316), Expect = 6e-29
Identities = 93/338 (27%), Positives = 158/338 (46%), Gaps = 38/338 (11%)
Query: 8 GKQDIRYTKDLEEPVIE-TDDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLG 66
G +D+R + P+ E DD + + + GICGSD+H + G++ D L
Sbjct: 12 GIEDLRLE---QRPIPEIADDEVLLAMDSVGICGSDVH--------YLAHGRIGDFV-LT 59
Query: 67 LPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVEATGTC--LDHYTWPNXXXXXXXXXXXCQ 124
P +GHE +G+V+K+G KVT +K GD V +E C DH C+
Sbjct: 60 KPMIIGHEAAGVVAKLGKKVTTLKVGDRVAIEPGVPCRYCDH----------------CK 103
Query: 125 RGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRI 184
+G YN CA + F + G +P+ + ++ AL+EP+SV HA R
Sbjct: 104 QGRYNLCADMVFCATPPYDGNLTRYYKHAADFCFKLPDHVSMEEGALLEPLSVGVHACRR 163
Query: 185 SKLQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVE---TFDPS 241
+ + G L+LGAGPIGL T+LA Q GAS+I++++ + R + A +LG
Sbjct: 164 AGVGLGSKVLILGAGPIGLVTLLAAQAMGASEILITDLVQQRLDVAKELGATHTLLLQRD 223
Query: 242 EHKEDAVNILKKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFK 301
+ E+ V ++ + E D + DC G + + + AT G+ V + + G +
Sbjct: 224 QSAEETVKVVHQTM--SEVPDKSIDCCGAESSARLAIFATRSGGVVVVVGM-GAPEVKLP 280
Query: 302 PMDVTLQEKFVTGSMCYTIKDFEDVVQALGNGSIAIDK 339
++ +E + G Y D+ + + +G + + +
Sbjct: 281 LINALAREIDIRGVFRY-CNDYSAALALVASGKVNVKR 317
>7298873 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 124 bits (310), Expect = 3e-28
Identities = 98/371 (26%), Positives = 172/371 (45%), Gaps = 40/371 (10%)
Query: 8 GKQDIRYTKDLEEPVIE-TDDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLG 66
G +D+R + P+ E DD + + + GICGSD+H + G++ D L
Sbjct: 12 GIEDMRLE---QRPIPEIADDEVLLAMDSVGICGSDVH--------YLAHGRIGDFV-LT 59
Query: 67 LPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVEATGTC--LDHYTWPNXXXXXXXXXXXCQ 124
P +GHE +G+V+K+G KVT +K GD V +E C DH C+
Sbjct: 60 KPMIIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDH----------------CK 103
Query: 125 RGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRI 184
+G YN C + F + G +P+ + ++ AL+EP+SV HA +
Sbjct: 104 QGKYNLCPGMVFCATPPYDGNLTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKR 163
Query: 185 SKLQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGV--ETFDPSE 242
+++ G L+LGAGPIGL T++A Q GAS+I++++ + R + A +LG +
Sbjct: 164 AEVTLGSKVLILGAGPIGLVTLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRD 223
Query: 243 HKEDAVNILKKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKP 302
+ +L + GG+ D + DC G + + + AT G+ V + + G I
Sbjct: 224 QTAEETAVLVQKTMGGQP-DKSIDCCGAESSARLAIFATRSGGIVVVVGM-GAAEIKLPL 281
Query: 303 MDVTLQEKFVTGSMCYTIKDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDELM 362
++ +E + G Y D+ + + +G + + + L+T I++ K F+
Sbjct: 282 INALAREVDIRGVFRY-CNDYAAALALVASGKVNV---KRLVTHHFDIKE-TAKAFETSR 336
Query: 363 NHKEKNIKILL 373
IK+++
Sbjct: 337 KGLGGAIKVMI 347
>CE06215 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 121 bits (303), Expect = 2e-27
Identities = 85/308 (27%), Positives = 142/308 (45%), Gaps = 30/308 (9%)
Query: 31 IEVSWCGICGSDLHEYLDGPI--FFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
++V GICGSD+H + G I F ++ P +GHE SGIVS+VG +V +
Sbjct: 33 VKVHTVGICGSDVHYWTHGAIGPFVVKE-----------PMIVGHETSGIVSEVGNEVKH 81
Query: 89 IKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGGFAX 148
+K GD + +E C C+ G YN C + F G +
Sbjct: 82 LKVGDRIAMEPGLPC--------------KLCEHCKTGRYNLCPEMRFFATPPVHGTLSR 127
Query: 149 XXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLATILA 208
+P+ L + AL+EP+SV+ HA R +Q G LVLGAGPIG+ ++
Sbjct: 128 FVVHDADFCFKLPDNLSFEDGALIEPLSVAIHACRRGNVQMGHRVLVLGAGPIGVLNLIT 187
Query: 209 LQGHGASKIVVSEPAEIRRNQAAKLGVE-TFDPSEHKEDAVNILKKLAPGGEGFDFAYDC 267
+ GA K+V+++ + R A KLG + T + DAV A G + D +C
Sbjct: 188 AKAVGAGKVVITDLDDGRLALAKKLGADATINVKGKSLDAVKSEIITALGDQQPDVCIEC 247
Query: 268 SGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSMCYTIKDFEDVV 327
+G +P+ +T + T G+ V + + G ++ ++ +E + G Y + + +
Sbjct: 248 TGAQPSIETAITTTKSGGVIVLVGL-GADRVEIPIIESATREVDMRGIFRY-VNCYPTAI 305
Query: 328 QALGNGSI 335
+ + +G +
Sbjct: 306 ELISSGKL 313
>YLR070c [Q] KOG0024 Sorbitol dehydrogenase
Length = 356
Score = 119 bits (299), Expect = 6e-27
Identities = 94/358 (26%), Positives = 155/358 (43%), Gaps = 36/358 (10%)
Query: 21 PVIETDDGIEIEVSWCGICGSDLHEYLDGPI--FFPEDGKVHDVSGLGLPQAMGHEMSGI 78
P I + + I++ GICGSD+H Y G I + E P +GHE SGI
Sbjct: 26 PKISDPNEVIIQIKATGICGSDIHYYTHGRIANYVVES-----------PMVLGHESSGI 74
Query: 79 VSKVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMG 138
V+ +G V +K GD V +E D ++ + G YN +L F
Sbjct: 75 VALIGENVKTLKVGDRVALEPG--IPDRFS------------PEMKEGRYNLDPNLKFAA 120
Query: 139 LGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGA 198
G +P+ + + AL+EP+SV+ HA +++K++ G +V GA
Sbjct: 121 TPPFDGTLTKYYKTMKDFVYKLPDDVSFEEGALIEPLSVAIHANKLAKIKFGARCVVFGA 180
Query: 199 GPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDPS---EHKEDAVNILKKLA 255
GPIGL GA+ +V + E + A + G S H +++KK A
Sbjct: 181 GPIGLLAGKVASVFGAADVVFVDLLENKLETARQFGATHIVNSGDLPHGVTVDSVIKK-A 239
Query: 256 PGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGS 315
G +G D ++CSG +P G+ G V + + G + I F + +E G
Sbjct: 240 IGKKGADVVFECSGAEPCVRAGIEVCKAGGTIVQVGM-GQEEIQFPISIIPTKELTFQGC 298
Query: 316 MCYTIKDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDELMNHKEKNIKILL 373
Y D+ D ++ + + +++ + IT R +D + F+E +H NIK ++
Sbjct: 299 FRYCQGDYSDSIELVSSRKLSL---KPFITHRYSFKDA-VEAFEETSHHPLNNIKTII 352
>SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 116 bits (290), Expect = 6e-26
Identities = 98/365 (26%), Positives = 159/365 (42%), Gaps = 35/365 (9%)
Query: 16 KDLEEPVIETDDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEM 75
+D + D +++ + GICGSD+H + ++G + D L P +GHE
Sbjct: 19 EDRPGQTLTDDHQVKVAIKATGICGSDVHYW--------KEGGIGDFI-LKKPMILGHES 69
Query: 76 SGIVSKVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLG 135
+G+V +VG V+++K GD V VE C C+ G YN C H+
Sbjct: 70 AGVVVEVGKGVSSLKPGDPVAVEPGCVC--------------RLCDYCRSGRYNLCPHME 115
Query: 136 FMGLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALV 195
F + G +P + ++ AL EP+SV+ HA+ L+ G LV
Sbjct: 116 FAATPPYDGTLRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTRGNLKCGSRVLV 175
Query: 196 LGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAK-LGVETFDPSEHKED------AV 248
+G G +GL + + +GA IV + + R A K +G + F P KE+ A
Sbjct: 176 MGCGTVGLLMMAVAKAYGAIDIVAVDASPSRVEFAQKYVGAKPFTPIAAKENESLPDYAQ 235
Query: 249 NILKKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQ 308
+ + FDFA D +GV T V A G +V A G IDF +
Sbjct: 236 RYKQAIIEKYGEFDFAVDATGVGICIHTAVLALKRGGTFVQ-AGNGKPVIDFPINHIINY 294
Query: 309 EKFVTGSMCYTIKDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDELMNHKEKN 368
E V GS Y ++ + + NG + + + LIT R +D K ++ + + +E
Sbjct: 295 EINVLGSFRYAHGCYKQSLFLVSNGLVDV---KPLITHRFAFKDAL-KAYETVASGEEGV 350
Query: 369 IKILL 373
+K+++
Sbjct: 351 LKVII 355
>CE06216 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 113 bits (282), Expect = 5e-25
Identities = 77/265 (29%), Positives = 123/265 (46%), Gaps = 28/265 (10%)
Query: 31 IEVSWCGICGSDLHEYLDGPI--FFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
++++ GICGSD+H G I F ++ P +GHE SG+VS++G +V
Sbjct: 33 VKINTVGICGSDVHFLTHGAIGSFVVKE-----------PMVLGHESSGVVSEIGSEVKG 81
Query: 89 IKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGGFAX 148
K GD + +E C C+ G YN C + F +G +
Sbjct: 82 FKVGDRIAMEPGLPC--------------KLCEHCKIGRYNLCPDMRFFATPPVNGALSR 127
Query: 149 XXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLATILA 208
+P+ L + AL+EP+SV+ A R +Q GQ LVLGAGPIG+ +L
Sbjct: 128 FVVHDADFCFKLPDNLSFEDGALLEPLSVAIQACRRGTVQMGQKILVLGAGPIGVLNLLT 187
Query: 209 LQGHGASKIVVSEPAEIRRNQAAKLGVE-TFDPSEHKEDAVNILKKLAPGGEGFDFAYDC 267
+ GASK+V+++ + R A LG + T + + D V A G + + +C
Sbjct: 188 AKAIGASKVVITDLNDERLALARLLGADATINVMGKRSDEVRSEIIKAFGDQQPHVSIEC 247
Query: 268 SGVKPTFDTGVHATTFRGMYVNIAI 292
+GV+P +T + T G+ V + +
Sbjct: 248 TGVQPCVETAIMTTRSGGVVVLVGL 272
>At5g51970 [Q] KOG0024 Sorbitol dehydrogenase
Length = 364
Score = 105 bits (263), Expect = 9e-23
Identities = 92/333 (27%), Positives = 147/333 (43%), Gaps = 35/333 (10%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ + + GICGSD+H YL D V + P +GHE +GI+ +VG +V +
Sbjct: 44 VRVRMKAVGICGSDVH-YLK--TMRCADFVVKE------PMVIGHECAGIIEEVGEEVKH 94
Query: 89 IKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGGFAX 148
+ GD V +E +C W C+ G YN C + F G A
Sbjct: 95 LVVGDRVALEPGISC-----W---------RCNLCREGRYNLCPEMKFFATPPVHGSLAN 140
Query: 149 XXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLATILA 208
+P + L+ A+ EP+SV HA R +++ + LV+GAGPIGL T+LA
Sbjct: 141 QVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLVTMLA 200
Query: 209 LQGHGASKIVVSEPAEIRRNQAAKLGV-ETFDPSEHKEDAVNILKKLAPG-GEGFDFAYD 266
+ +IV+ + E R A +LG E + + ED + ++++ G D +D
Sbjct: 201 ARAFSVPRIVIVDVDENRLAVAKQLGADEIVQVTTNLEDVGSEVEQIQKAMGSNIDVTFD 260
Query: 267 CSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSMCYTIKDFEDV 326
C+G T T + AT G + + GH + +E V G Y +
Sbjct: 261 CAGFNKTMSTALAATRCGGKVCLVGM-GHGIMTVPLTPAAAREVDVVGVFRYK-NTWPLC 318
Query: 327 VQALGNGSIAIDKARHLITGR-----QKIEDGF 354
++ L +G I + + LIT R +++ED F
Sbjct: 319 LEFLTSGKIDV---KPLITHRFGFSQKEVEDAF 348
>Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 102 bits (253), Expect = 1e-21
Identities = 71/257 (27%), Positives = 115/257 (44%), Gaps = 25/257 (9%)
Query: 37 GICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVV 96
GICGSD+H + E G++ + + P +GHE SG V KVG V ++K GD V
Sbjct: 43 GICGSDVHYW--------EYGRIGNFI-VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVA 93
Query: 97 VEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXX 156
+E C+ G YN + F G
Sbjct: 94 IEPGAP--------------RENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAF 139
Query: 157 XXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLATILALQGHGASK 216
+P+ + + AL+EP+SV HA R + G LV GAGPIG+ T+L + GA++
Sbjct: 140 CYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQ 199
Query: 217 IVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKL-APGGEGFDFAYDCSGVKPTFD 275
+VV++ + R ++A ++G + KE I +K+ G + +C+G + +
Sbjct: 200 VVVTDLSATRLSKAKEIGADLV-LQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQ 258
Query: 276 TGVHATTFRGMYVNIAI 292
G++AT G V + +
Sbjct: 259 AGIYATRSGGTLVLVGL 275
>Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 91.3 bits (225), Expect = 2e-18
Identities = 66/241 (27%), Positives = 107/241 (44%), Gaps = 33/241 (13%)
Query: 37 GICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVV 96
GICGSD+H + E G++ + + P +GHE SG V KVG V ++K GD V
Sbjct: 5 GICGSDVHYW--------EYGRIGNFI-VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVA 55
Query: 97 VEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXX 156
+E+ C+ G YN + F G
Sbjct: 56 IESGAP--------------RENDEFCKMGRYNLSPSIFFCATPPDDGNLCQFYKHNAAF 101
Query: 157 XXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLATILALQGHGASK 216
+P+ + + AL++P+SV HA R + G LV GAG IG+ T+L + GA++
Sbjct: 102 CYKLPDNVTFEEGALIDPLSVGIHACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQ 161
Query: 217 IVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKLAPGGEGF-----DFAYDCSGVK 271
+VV++ + R ++A ++G + KE I +K+ EG + +C+G +
Sbjct: 162 VVVTDLSATRLSKAKEIGADLV-LQISKESPQEIARKV----EGLLGCKPEVTIECTGQR 216
Query: 272 P 272
P
Sbjct: 217 P 217
>Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 90.1 bits (222), Expect = 5e-18
Identities = 69/263 (26%), Positives = 113/263 (42%), Gaps = 36/263 (13%)
Query: 37 GICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVV 96
GICGSD+H + E G++ + + P +GHE SG V KVG ++K GD V
Sbjct: 5 GICGSDVHYW--------EYGRIGNFI-VKKPMVLGHEASGTVEKVGSSAKHLKPGDRVA 55
Query: 97 VEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXX 156
+E+ C+ G YN + F G
Sbjct: 56 IESGAP--------------RENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAF 101
Query: 157 XXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLATILALQGHGASK 216
+P+ + + AL++P+SV HA R + G LV GAG IG+ T+L + GA++
Sbjct: 102 CYKLPDNVTFEEGALIDPLSVGIHACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQ 161
Query: 217 IVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKLAPGGEGF-----DFAYDCSGVK 271
+VV++ + R ++A ++G + KE I +K+ EG + +C+G +
Sbjct: 162 VVVTDLSATRLSKAKEIGADLV-LQISKESPQEIARKV----EGLLGCKPEVTIECTGQR 216
Query: 272 PTFDTGVHATTFRGMYVNIAIWG 294
P A+T + +WG
Sbjct: 217 P---PSRQASTPLALVGTSCLWG 236
>SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 378
Score = 75.5 bits (184), Expect = 1e-13
Identities = 90/376 (23%), Positives = 154/376 (40%), Gaps = 64/376 (17%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ ++V W +C +D + L G D G P +GHE +GIV +G V N
Sbjct: 37 VRVKVDWSAVCHTDAYT-LSGV----------DPEG-AFPIVLGHEGAGIVESIGEGVIN 84
Query: 89 IKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHL------GFMGLG-- 140
++ GDHV++ T C + C+ G N C+ + G M G
Sbjct: 85 VRPGDHVILLYTPECKE--------------CKFCRSGKTNLCSKIRETQGRGLMPDGTS 130
Query: 141 ---------VHSGG---FAXXXXXXXXXXXXIPNTLPL-DVAALVEPISVSWHAVRIS-K 186
+H G F+ I ++ PL + L ++ + AV S K
Sbjct: 131 RFSCRDKTLLHYMGCSSFSQYTVVADISLVAISHSAPLRSICLLGCGVTTGFGAVTHSAK 190
Query: 187 LQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDPSEHKED 246
++ G + V+G G +GLA + GAS+I+ + + A K G F S +D
Sbjct: 191 VESGSTVAVVGCGCVGLAAMQGAVAAGASRIIAIDINADKEVYAKKFGATDFIDSSKVKD 250
Query: 247 AVNILKKLAPGGEGFDFAYDCSGVKPTFDTGV---HATTFRGMYVNIAIWGHKPIDFKPM 303
V + + G G D+A+DC+G + H + + +A G K +DF+P
Sbjct: 251 LVQYVIDVTDG--GVDYAFDCTGNVTVMQQELQFCHKGWGKLCVIGVAAAG-KTLDFRPF 307
Query: 304 DVTLQEKFVTGSMCYTIK---DFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDE 360
+ + + V GS +K + + V G +D+ IT + +++ K FD
Sbjct: 308 -LVVTGRQVLGSAFGGVKGRSELPNFVDEYMQGHFKVDE---YITNEEPLKN-INKAFDH 362
Query: 361 LMNHKEKNIKILLTPN 376
+ H+ K I+ ++ N
Sbjct: 363 M--HEGKCIRCVVDMN 376
>YDL168w [Q] KOG0022 Alcohol dehydrogenase class III
Length = 386
Score = 72.8 bits (177), Expect = 8e-13
Identities = 74/294 (25%), Positives = 117/294 (39%), Gaps = 57/294 (19%)
Query: 3 ALAYFGKQDIRYTKDLEEPVIETDDG--IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVH 60
A+AY K+ + +EE ++ + I++ + +C +D + L G
Sbjct: 15 AVAYDAKKPL----SVEEITVDAPKAHEVRIKIEYTAVCHTDAYT-LSGS---------- 59
Query: 61 DVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXX 120
D GL P +GHE +GIV VG V +K GDHV+ T C
Sbjct: 60 DPEGL-FPCVLGHEGAGIVESVGDDVITVKPGDHVIALYTAEC--------------GKC 104
Query: 121 XXCQRGFYNCCAHL-GFMGLGVHSGG--------------------FAXXXXXXXXXXXX 159
C G N C + G GV G F+
Sbjct: 105 KFCTSGKTNLCGAVRATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADVSVVA 164
Query: 160 IPNTLPLDVAALVE-PISVSWHA-VRISKLQKGQSALVLGAGPIGLATILALQGHGASKI 217
I PLD A L+ ++ + A ++ + +QKG + V G G +GL+ I + GASKI
Sbjct: 165 IDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKLRGASKI 224
Query: 218 VVSEPAEIRRNQAAKLGVETF-DPSEHKEDAVNILKKLAPGGE-GFDFAYDCSG 269
+ + ++ ++ G F +P E I++KL + G DF +DC+G
Sbjct: 225 IAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGGLDFTFDCTG 278
>At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 359
Score = 72.4 bits (176), Expect = 1e-12
Identities = 85/345 (24%), Positives = 137/345 (39%), Gaps = 65/345 (18%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGL-PQAMGHEMSGIVSKVGPKVT 87
+ +V +CGIC SDLH V + G+ P GHE+ G+V++VG KVT
Sbjct: 36 VRFKVLFCGICHSDLH-------------MVKNEWGMSTYPLVPGHEIVGVVTEVGAKVT 82
Query: 88 NIKAGDHV----VVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAH------LGFM 137
K G+ V +V + G+C C G N C +
Sbjct: 83 KFKTGEKVGVGCLVSSCGSC-----------------DSCTEGMENYCPKSIQTYGFPYY 125
Query: 138 GLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAA--LVEPISVSWHAVRISKLQK-GQSAL 194
+ GG++ IP+ LPLD AA L I+V + ++ L K G
Sbjct: 126 DNTITYGGYSDHMVCEEGFVIRIPDNLPLDAAAPLLCAGITV-YSPMKYHGLDKPGMHIG 184
Query: 195 VLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF----DPSEHKEDAVNI 250
V+G G +G + + G V+S + R +LG + F DP + K DA+
Sbjct: 185 VVGLGGLGHVGVKFAKAMGTKVTVISTSEKKRDEAINRLGADAFLVSRDPKQIK-DAMGT 243
Query: 251 LKKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEK 310
+ + D + P H +G V + KP++ M + + K
Sbjct: 244 MDGI------IDTVSATHSLLPLLGLLKH----KGKLVMVGA-PEKPLELPVMPLIFERK 292
Query: 311 FVTGSMCYTIKDFEDVVQALGNGSIAID----KARHLITGRQKIE 351
V GSM IK+ ++++ G +I D A ++ T +++E
Sbjct: 293 MVMGSMIGGIKETQEMIDMAGKHNITADIELISADYVNTAMERLE 337
>Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 71.2 bits (173), Expect = 2e-12
Identities = 63/253 (24%), Positives = 106/253 (40%), Gaps = 40/253 (15%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ I++ GICG+D H + G + P LP +GHE +GIV VG VT
Sbjct: 37 VRIKMVAVGICGTDDH-VVSGTMVTP------------LPVILGHEAAGIVESVGEGVTT 83
Query: 89 IKAGDHVVVEATGTC---------------LDHYTWPNXXXXXXXXXXXCQRGFYNCCAH 133
+K GD V+ A C + + P C+R +
Sbjct: 84 VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIH---- 139
Query: 134 LGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVE-PISVSW-HAVRISKLQKGQ 191
F+G+ F+ I PL+ L+ S + AV ++K+ G
Sbjct: 140 -HFLGIST----FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194
Query: 192 SALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLG-VETFDPSEHKEDAVNI 250
+ V G G +GL+ I+ + GA++I+ + + + +A +LG E +P ++K+ +
Sbjct: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254
Query: 251 LKKLAPGGEGFDF 263
LK++ GG F F
Sbjct: 255 LKEMTDGGVDFSF 267
>Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 70.9 bits (172), Expect = 3e-12
Identities = 64/247 (25%), Positives = 105/247 (41%), Gaps = 28/247 (11%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ I++ GIC SD H + G + P LP +GHE +GIV VG VT
Sbjct: 37 VRIKMVAAGICRSDEH-VVSGNLVTP------------LPVILGHEAAGIVESVGEGVTT 83
Query: 89 IKAGDHVVVEATGTC---------LDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGL 139
+K GD V+ T C +Y N R F C +
Sbjct: 84 VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF-TCSGKPIHHFV 142
Query: 140 GVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVE-PISVSW-HAVRISKLQKGQSALVLG 197
GV + F+ I PL+ L+ S + AV+++K+ G + V G
Sbjct: 143 GVST--FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFG 200
Query: 198 AGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLG-VETFDPSEHKEDAVNILKKLAP 256
G +GL+ ++ + GA++I+ + + + +A +LG E +P ++K+ +LK++
Sbjct: 201 LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260
Query: 257 GGEGFDF 263
GG F F
Sbjct: 261 GGVDFSF 267
>At5g43940 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 67.8 bits (164), Expect = 3e-11
Identities = 65/268 (24%), Positives = 107/268 (39%), Gaps = 58/268 (21%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ I++ + +C +D + + GK D GL P +GHE +GIV VG VT
Sbjct: 37 VRIKILYTALCHTDAYTW---------SGK--DPEGL-FPCILGHEAAGIVESVGEGVTE 84
Query: 89 IKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHL-GFMGLGV------ 141
++AGDHV+ C + C+ G N C + G+G+
Sbjct: 85 VQAGDHVIPCYQAECRE--------------CKFCKSGKTNLCGKVRSATGVGIMMNDRK 130
Query: 142 -----------HSGG---FAXXXXXXXXXXXXIPNTLPLDVAALV-----EPISVSWHAV 182
H G F+ I T PLD L+ + W+
Sbjct: 131 SRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWNT- 189
Query: 183 RISKLQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF-DPS 241
+K++ G + + G G +GLA + GAS+I+ + + A K GV F +P
Sbjct: 190 --AKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVNPK 247
Query: 242 EHKEDAVNILKKLAPGGEGFDFAYDCSG 269
+H + ++ L G G D++++C G
Sbjct: 248 DHDKPIQEVIVDLTDG--GVDYSFECIG 273
>SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 350
Score = 67.4 bits (163), Expect = 3e-11
Identities = 64/254 (25%), Positives = 104/254 (40%), Gaps = 32/254 (12%)
Query: 8 GKQDIRYTKDLEEPVIET-DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLG 66
G +++++ E PV E D + + + + G+C +DLH L G P
Sbjct: 17 GPENVKFE---EVPVAEPGQDEVLVNIKYTGVCHTDLHA-LQGDWPLPAK---------- 62
Query: 67 LPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRG 126
+P GHE +G+V KVG VT +K GD V V+ W N C +
Sbjct: 63 MPLIGGHEGAGVVVKVGAGVTRLKIGDRVGVK----------WMN---SSCGNCEYCMKA 109
Query: 127 FYNCCAHLGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVS-WHAVRIS 185
C H+ G V G F IP ++PL+VAA + ++ + A++ S
Sbjct: 110 EETICPHIQLSGYTV-DGTFQHYCIANATHATIIPESVPLEVAAPIMCAGITCYRALKES 168
Query: 186 KLQKGQSALVLGAGPIGLATILALQGHG-ASKIVVSEPAEIRRNQAAKLGVETFDPSEHK 244
K+ G+ + GAG GL + A ++V + + + G E F + +
Sbjct: 169 KVGPGEWICIPGAGG-GLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFLDFKKE 227
Query: 245 EDAVNILKKLAPGG 258
D + +K GG
Sbjct: 228 ADMIEAVKAATNGG 241
>Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 67.0 bits (162), Expect = 4e-11
Identities = 63/247 (25%), Positives = 103/247 (41%), Gaps = 28/247 (11%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ I++ GIC +D H + G + P LP +GHE +GIV VG VT
Sbjct: 37 VRIKMVAVGICHTDDH-VVSGNLVTP------------LPVILGHEAAGIVESVGEGVTT 83
Query: 89 IKAGDHVVVEATGTC---------LDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGL 139
+K GD V+ T C +Y N R F C L
Sbjct: 84 VKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF-TCRGKPIHHFL 142
Query: 140 GVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVE-PISVSW-HAVRISKLQKGQSALVLG 197
G + F+ I PL+ L+ S + AV ++K+ G + V G
Sbjct: 143 GTST--FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFG 200
Query: 198 AGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLG-VETFDPSEHKEDAVNILKKLAP 256
G +GL+ ++ + GA++I+ + + + +A +LG E +P ++K+ +LK++
Sbjct: 201 LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260
Query: 257 GGEGFDF 263
GG F F
Sbjct: 261 GGVDFSF 267
>At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 355
Score = 67.0 bits (162), Expect = 4e-11
Identities = 76/300 (25%), Positives = 114/300 (37%), Gaps = 42/300 (14%)
Query: 25 TDDGIEIEVSWCGICGSDL----HEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVS 80
T D + + ++ CG+C +D+ +++ D P GHE++GIV+
Sbjct: 34 TTDDVSLTITHCGVCYADVIWSRNQHGDSKY----------------PLVPGHEIAGIVT 77
Query: 81 KVGPKVTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGF--YNCCAHLGFMG 138
KVGP V K GDHV V + N C +G +N H G
Sbjct: 78 KVGPNVQRFKVGDHVGVGTYVNSCRECEYCN-----EGQEVNCAKGVFTFNGIDHDG--- 129
Query: 139 LGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAA--LVEPISVSWHAVRISKLQKGQSALVL 196
V GG++ IP PL+ AA L I+V +R + Q G+S V+
Sbjct: 130 -SVTKGGYSSHIVVHERYCYKIPVDYPLESAAPLLCAGITVYAPMMRHNMNQPGKSLGVI 188
Query: 197 GAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKLAP 256
G G +G + + G S V S + LG E F S D + L+K
Sbjct: 189 GLGGLGHMAVKFGKAFGLSVTVFSTSISKKEEALNLLGAENFVISS-DHDQMKALEK--- 244
Query: 257 GGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSM 316
DF D + FD + G YV + I P ++ L + + GS+
Sbjct: 245 ---SLDFLVDTASGDHAFDPYMSLLKIAGTYVLVGF--PSEIKISPANLNLGMRMLAGSV 299
>CE20628 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 408
Score = 66.2 bits (160), Expect = 8e-11
Identities = 77/355 (21%), Positives = 144/355 (39%), Gaps = 25/355 (7%)
Query: 26 DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK 85
+D + +++ + GIC SD+H +L G H VS P GHE +G V VG K
Sbjct: 34 EDELLVKMEYSGICHSDVHTWL---------GDFHYVSKC--PMIGGHEGAGSVISVGSK 82
Query: 86 VTNIKAGDHVVVEATGTCLD---HYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVH 142
V N + GD V ++ + T ++ CQ G C H+ +G+ +
Sbjct: 83 VKNWQIGDKVGIKVSQTLNSSSLNFNIFQLVQGNCLNCEYCQTGHEPLCPHVWNIGVQKY 142
Query: 143 SGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISV-SWHAVRISKLQKGQSALVLGA-GP 200
G F IP ++ + AA V V ++ A++ S+++ GQ V GA G
Sbjct: 143 -GTFQEYATIRDVDAIKIPKSMNMAAAAPVLCGGVTAYKALKESEVKSGQIVAVTGAGGG 201
Query: 201 IGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKLAPGGEG 260
+G I + G + + P+ + LG E F + ED V ++++ GG
Sbjct: 202 LGSFAIQYARAMGMRVVAIDHPS--KEAHCKSLGAEWFVDAFGTEDIVAHIREITDGGA- 258
Query: 261 FDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSMCYTI 320
+ + K + + RG V + + I + + + GS+ +
Sbjct: 259 -HGVVNFAAAKVPMEKALEYVRKRGTVVFVGLAKDSKILVDTIPLIFNAVKIKGSIVGSR 317
Query: 321 KDFEDVVQALGNGSIAIDKARHLITGRQKIEDGFTKGFDELMNHKEKNIKILLTP 375
D + + + G++ + + + + + +TK D +N ++ + + L P
Sbjct: 318 LDVNEAMDFVARGAVNVPLE---LVKLEDVAEVYTKMHDGKINSRQL-LSVFLNP 368
>7299380 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 66.2 bits (160), Expect = 8e-11
Identities = 76/278 (27%), Positives = 107/278 (38%), Gaps = 53/278 (19%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ I+++ G+C +D L G D GL P +GHE +GIV VG VTN
Sbjct: 38 VRIKITATGVCHTDAFT-LSGA----------DPEGL-FPVVLGHEGAGIVESVGEGVTN 85
Query: 89 IKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGF-MGLGVHSGG-- 145
KAGDHV+ C + C+ G N C + G GV G
Sbjct: 86 FKAGDHVIALYIPQCNE--------------CKFCKSGKTNLCQKIRLTQGAGVMPEGTS 131
Query: 146 -----------------FAXXXXXXXXXXXXIPNTLPLDVAALVE-PISVSW-HAVRISK 186
FA I PL+ L+ IS + A+ +K
Sbjct: 132 RLSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAK 191
Query: 187 LQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF-DPSE--H 243
++ G + V G G +GLA L + GA KI + + A K G F +P +
Sbjct: 192 VEAGSTCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVAD 251
Query: 244 KEDAVNILKKLAPGGEGFDFAYDCSGVKPTFDTGVHAT 281
K N L L G GFD+ ++C G T + + AT
Sbjct: 252 KGSIQNYLIDLTDG--GFDYTFECIGNVNTMRSALEAT 287
>At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 376
Score = 61.2 bits (147), Expect = 2e-09
Identities = 75/328 (22%), Positives = 123/328 (36%), Gaps = 53/328 (16%)
Query: 26 DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK 85
++ + +++ +CG+C SDLH + F P GHE+ GI +KVG
Sbjct: 31 ENDVTVKILFCGVCHSDLHTIKNHWGFSR------------YPIIPGHEIVGIATKVGKN 78
Query: 86 VTNIKAGDHVVVEA-TGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFM------- 137
VT K GD V V G+C C + N C + F
Sbjct: 79 VTKFKEGDRVGVGVIIGSC--------------QSCESCNQDLENYCPKVVFTYNSRSSD 124
Query: 138 GLGVHSGGFAXXXXXXXXXXXXIPNTLPLDVAA--LVEPISVSWHAVRISKLQK--GQSA 193
G + GG++ IP+ LP D A L I+V + ++ + K G+
Sbjct: 125 GTSRNQGGYSDVIVVDHRFVLSIPDGLPSDSGAPLLCAGITV-YSPMKYYGMTKESGKRL 183
Query: 194 LVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF---DPSEHKEDAVNI 250
V G G +G + + G V+S +E R +LG ++F S+ ++AV
Sbjct: 184 GVNGLGGLGHIAVKIGKAFGLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAVGT 243
Query: 251 LKKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEK 310
+ DF D + G V + + KP+D + L K
Sbjct: 244 M----------DFIIDTVSAEHALLPLFSLLKVNGKLVALGL-PEKPLDLPIFSLVLGRK 292
Query: 311 FVTGSMCYTIKDFEDVVQALGNGSIAID 338
V GS +K+ +++++ I D
Sbjct: 293 MVGGSQIGGMKETQEMLEFCAKHKIVSD 320
>SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 380
Score = 60.8 bits (146), Expect = 3e-09
Identities = 67/264 (25%), Positives = 104/264 (39%), Gaps = 51/264 (19%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTN 88
+ I++ G+C +D + GK D GL P +GHE +GIV VGP+VT
Sbjct: 40 VRIKIVNSGVCHTDAYTL---------SGK--DPEGL-FPVILGHEGAGIVESVGPQVTT 87
Query: 89 IKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHL------GFMGLG-- 140
++ GD V+ T C C+ G N C + G M G
Sbjct: 88 VQVGDPVIALYTPEC--------------KTCKFCKSGKTNLCGRIRTTQGKGLMPDGTS 133
Query: 141 ---------VHSGG---FAXXXXXXXXXXXXIPNTLPLDVAALVE-PISVSWHAVRI-SK 186
+H G F+ I PLD L+ I+ + A I +
Sbjct: 134 RFSCNGNTLLHFMGCSTFSEYTVVADISVVAIERLAPLDSVCLLGCGITTGYGAATITAD 193
Query: 187 LQKGQSALVLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF-DPSEHKE 245
+++G S V G G +GLA I A +I + ++N A G F +P++ +
Sbjct: 194 IKEGDSVAVFGLGSVGLAVIQGAVKKRAGRIFGIDVNPEKKNWAMSFGATDFINPNDLQS 253
Query: 246 DAVNILKKLAPGGEGFDFAYDCSG 269
++L G G D+ +DC+G
Sbjct: 254 PIQDVLIHETDG--GLDWTFDCTG 275
>7300579 [Q] KOG0024 Sorbitol dehydrogenase
Length = 1139
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/195 (21%), Positives = 83/195 (42%), Gaps = 33/195 (16%)
Query: 26 DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK 85
D + I + SD+H Y +G D+ + L GH+ +GIV ++G
Sbjct: 821 DFDVLIRTGSVAVSNSDIHVYENGN---------RDMEAMSL----GHDATGIVEELGRC 867
Query: 86 VTNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGG 145
V ++ GD VV+E+ +C C++G YN C+ L V++G
Sbjct: 868 VQHLHVGDRVVMESALSC--------------GICDLCKKGLYNMCSGL------VYNGF 907
Query: 146 FAXXXXXXXXXXXXIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLAT 205
+ +P ++ ++ AL + +++ A + + + L+LGA P +A
Sbjct: 908 LSTYQTHPADLCHRLPESISMEAGALTQTLALGCQACFKANVTPTSNVLILGACPTAVAA 967
Query: 206 ILALQGHGASKIVVS 220
+ + GA ++ ++
Sbjct: 968 GICAKAIGAKRVAIA 982
>CE12212 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 349
Score = 57.8 bits (138), Expect = 3e-08
Identities = 73/316 (23%), Positives = 120/316 (37%), Gaps = 35/316 (11%)
Query: 26 DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK 85
DD I +++ + GIC SDLH +L G + D+S P GHE +G V ++G
Sbjct: 33 DDEILVKIEYSGICHSDLHVWL---------GDLKDMS--VCPLVGGHEGAGSVVQIGKN 81
Query: 86 VTNIKAGDHVVVEATG-TCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSG 144
VT + GD V+ CL+ C++G C H+ G SG
Sbjct: 82 VTGWQLGDKAGVKLMNFNCLN--------------CEFCKKGHEPLCHHIQNYGFD-RSG 126
Query: 145 GFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVS-WHAVRISKLQKGQSALVLGAGPIGL 203
F I L AA + V+ + A++ S + GQ ++ GAG GL
Sbjct: 127 TFQEYLTIRGVDAAKINKDTNLAAAAPILCAGVTVYKALKESNVAPGQIIVLTGAGG-GL 185
Query: 204 ATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKLAPGGEG--F 261
++ VV+ + LG E F + D V+ + KL GG
Sbjct: 186 GSLAIQYACAMGMRVVAMDHGSKEAHCKGLGAEWFVDAFETPDIVSHITKLTEGGPHGVI 245
Query: 262 DFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSMCYTIK 321
+FA + + V RG V + + + F + GS+ +
Sbjct: 246 NFAV----ARKPMEQAVEYVRKRGTVVFVGLPKDSKVTFDTTPFIFNAITIKGSIVGSRL 301
Query: 322 DFEDVVQALGNGSIAI 337
D ++ ++ + G + +
Sbjct: 302 DVDEAMEFVTRGIVKV 317
>At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 57.4 bits (137), Expect = 4e-08
Identities = 75/327 (22%), Positives = 122/327 (36%), Gaps = 52/327 (15%)
Query: 26 DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK 85
++ + +++ +CG+C SDLH + F P GHE+ GI +KVG
Sbjct: 31 ENDVTVKILFCGVCHSDLHTIKNHWGFSR------------YPIIPGHEIVGIATKVGKN 78
Query: 86 VTNIKAGDHVVVEA-TGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHS- 143
VT K GD V V G+C C + N C + F S
Sbjct: 79 VTKFKEGDRVGVGVIIGSC--------------QSCESCNQDLENYCPKVVFTYNSRSSD 124
Query: 144 -----GGFAXXXXXXXXXXXXIPNTLPLDVAA--LVEPISVSWHAVRISKLQK--GQSAL 194
GG++ IP+ LP D A L I+V + ++ + K G+
Sbjct: 125 GTRNQGGYSDVIVVDHRFVLSIPDGLPSDSGAPLLCAGITV-YSPMKYYGMTKESGKRLG 183
Query: 195 VLGAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF---DPSEHKEDAVNIL 251
V G G +G + + G V+S +E R +LG ++F S+ ++AV +
Sbjct: 184 VNGLGGLGHIAVKIGKAFGLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAVGTM 243
Query: 252 KKLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKF 311
DF D + G V + + KP+D + L K
Sbjct: 244 ----------DFIIDTVSAEHALLPLFSLLKVSGKLVALGLL-EKPLDLPIFPLVLGRKM 292
Query: 312 VTGSMCYTIKDFEDVVQALGNGSIAID 338
V GS +K+ +++++ I D
Sbjct: 293 VGGSQIGGMKETQEMLEFCAKHKIVSD 319
>At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 56.2 bits (134), Expect = 8e-08
Identities = 79/330 (23%), Positives = 121/330 (35%), Gaps = 65/330 (19%)
Query: 29 IEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGL-PQAMGHEMSGIVSKVGPKVT 87
+ +V +CGIC +DL + GL P GHE+ G+V++VG KV
Sbjct: 36 VRFKVLFCGICHTDL-------------SMAKNEWGLTTYPLVPGHEIVGVVTEVGAKVK 82
Query: 88 NIKAGDHV-VVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHL-------GFMGL 139
AGD V V G+C C G N C + F
Sbjct: 83 KFNAGDKVGVGYMAGSC--------------RSCDSCNDGDENYCPKMILTSGAKNFDDT 128
Query: 140 GVHSGGFAXXXXXXXXXXXXIPNTLPLDVAALVEPISVS-WHAVRISKLQK-GQSALVLG 197
H GG++ IP+ LPLD AA + V+ + ++ L K G V+G
Sbjct: 129 MTH-GGYSDHMVCAEDFIIRIPDNLPLDGAAPLLCAGVTVYSPMKYHGLDKPGMHIGVVG 187
Query: 198 AGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF----DPSEHKEDAVNILKK 253
G +G + + G V+S R +LG + F DP + K DA+ +
Sbjct: 188 LGGLGHVAVKFAKAMGTKVTVISTSERKRDEAVTRLGADAFLVSRDPKQMK-DAMGTM-- 244
Query: 254 LAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVN---IAIWG--HKPIDFKPMDVTLQ 308
G+ T G+ N + + G +P++ +
Sbjct: 245 --------------DGIIDTVSATHPLLPLLGLLKNKGKLVMVGAPAEPLELPVFPLIFG 290
Query: 309 EKFVTGSMCYTIKDFEDVVQALGNGSIAID 338
K V GSM IK+ +++V G +I D
Sbjct: 291 RKMVVGSMVGGIKETQEMVDLAGKHNITAD 320
>At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 54.7 bits (130), Expect = 2e-07
Identities = 68/326 (20%), Positives = 115/326 (34%), Gaps = 51/326 (15%)
Query: 26 DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK 85
++ + +++ +CG+C +DLH + D P GHE+ GI +KVG
Sbjct: 37 ENDVTVKILFCGVCHTDLHTIKN------------DWGYSYYPVVPGHEIVGIATKVGKN 84
Query: 86 VTNIKAGDHVVVEA-TGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHS- 143
VT K GD V V +G+C C + N C + F + S
Sbjct: 85 VTKFKEGDRVGVGVISGSC--------------QSCESCDQDLENYCPQMSFTYNAIGSD 130
Query: 144 -----GGFAXXXXXXXXXXXXIPNTLPLDVAA--LVEPISVSWHAVRISKLQKGQSALVL 196
GG++ P LP D A L I+V + G+ V
Sbjct: 131 GTKNYGGYSENIVVDQRFVLRFPENLPSDSGAPLLCAGITVYSPMKYYGMTEAGKHLGVA 190
Query: 197 GAGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF----DPSEHKEDAVNILK 252
G G +G + + G V+S + LG ++F DP + K A+ +
Sbjct: 191 GLGGLGHVAVKIGKAFGLKVTVISSSSTKAEEAINHLGADSFLVTTDPQKMKA-AIGTM- 248
Query: 253 KLAPGGEGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFV 312
D+ D + G + + + KP++ + L K V
Sbjct: 249 ---------DYIIDTISAVHALYPLLGLLKVNGKLIALGL-PEKPLELPMFPLVLGRKMV 298
Query: 313 TGSMCYTIKDFEDVVQALGNGSIAID 338
GS +K+ ++++ +I D
Sbjct: 299 GGSDVGGMKETQEMLDFCAKHNITAD 324
>YBR145w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 52.4 bits (124), Expect = 1e-06
Identities = 62/261 (23%), Positives = 103/261 (38%), Gaps = 33/261 (12%)
Query: 2 RALAYFGKQDIRYTKDLEEPVIETDDGIEIEVSWCGICGSDLHEYL-DGPIFFPEDGKVH 60
+A+ ++ KD+ P + ++ I + V + G+C SDLH + D P
Sbjct: 11 KAIVFYETDGKLEYKDVTVPEPKPNE-ILVHVKYSGVCHSDLHAWHGDWPF--------- 60
Query: 61 DVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVE-ATGTCLDHYTWPNXXXXXXXX 119
L P GHE +G+V K+G V K GD ++ GTC+
Sbjct: 61 ---QLKFPLIGGHEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCM--------------S 103
Query: 120 XXXCQRGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPL-DVAALVEPISVS 178
C+ G + C +L G H G F IP + L +VA ++
Sbjct: 104 CEYCEVGNESQCPYLDGTGF-THDGTFQEYATADAVQAAHIPPNVNLAEVAPILCAGITV 162
Query: 179 WHAVRISKLQKGQSALVLGA-GPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVET 237
+ A++ + + GQ + GA G +G I G +++ + +R +LG E
Sbjct: 163 YKALKRANVIPGQWVTISGACGGLGSLAIQYALAMG-YRVIGIDGGNAKRKLFEQLGGEI 221
Query: 238 FDPSEHKEDAVNILKKLAPGG 258
F ++D V + K GG
Sbjct: 222 FIDFTEEKDIVGAIIKATNGG 242
>At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 52.0 bits (123), Expect = 1e-06
Identities = 63/310 (20%), Positives = 110/310 (35%), Gaps = 41/310 (13%)
Query: 27 DGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKV 86
+ + I + CGIC +DLH+ +D+ P GHE+ G V +VG V
Sbjct: 35 EDVNIRIICCGICHTDLHQ------------TKNDLGMSNYPMVPGHEVVGEVVEVGSDV 82
Query: 87 TNIKAGDHVVVEATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVH---- 142
+ GD V V C C+R C + V+
Sbjct: 83 SKFTVGDIVGVGCLVGCC-------------GGCSPCERDLEQYCPKKIWSYNDVYINGQ 129
Query: 143 --SGGFAXXXXXXXXXXXXIPNTLPLDVAA--LVEPISVSWHAVRISKLQKGQSALVLGA 198
GGFA IP + ++ AA L ++V Q G +LG
Sbjct: 130 PTQGGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGILGL 189
Query: 199 GPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKLAPGG 258
G +G + + G V+S + R LG + + + K++
Sbjct: 190 GGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQ-------AKMSELA 242
Query: 259 EGFDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSMCY 318
+ D+ D V + + G + + + + P+ F + L K +TGS
Sbjct: 243 DSLDYVIDTVPVHHALEPYLSLLKLDGKLILMGVI-NNPLQFLTPLLMLGRKVITGSFIG 301
Query: 319 TIKDFEDVVQ 328
++K+ E++++
Sbjct: 302 SMKETEEMLE 311
>YMR318c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/217 (26%), Positives = 89/217 (40%), Gaps = 26/217 (11%)
Query: 26 DDGIEIEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK 85
D I+I++ CG+CGSD+H + +P +GHE+ G V K+GPK
Sbjct: 33 DHDIDIKIEACGVCGSDIH------------CAAGHWGNMKMPLVVGHEIVGKVVKLGPK 80
Query: 86 V-TNIKAGDHVVVEA-TGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHS 143
+ +K G V V A +CL+ N Y+ G+ V
Sbjct: 81 SNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTT----YSQPYEDGY----VSQ 132
Query: 144 GGFAXXXXXXXXXXXXIPNTLPLDVAA--LVEPISVSWHAVRISKLQKGQSALVLGAGPI 201
GG+A IP +P +AA L ++V VR + G+ ++G G I
Sbjct: 133 GGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVR-NGCGPGKKVGIVGLGGI 191
Query: 202 GLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETF 238
G L + GA V+S + +R A K+G + +
Sbjct: 192 GSMGTLISKAMGAETYVISRSSR-KREDAMKMGADHY 227
>CE12214 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 51.6 bits (122), Expect = 2e-06
Identities = 71/329 (21%), Positives = 124/329 (37%), Gaps = 35/329 (10%)
Query: 31 IEVSWCGICGSDLHEYLDGPIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPKVTNIK 90
+++ + GIC SDLH + +G S P GHE +G V +G KV
Sbjct: 39 VKIEYSGICHSDLHTW---------EGDFEYASIC--PLIGGHEGAGTVVTIGSKVKGWN 87
Query: 91 AGDHVVVE-ATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAHLGFMGLGVHSGGFAXX 149
GD ++ CL+ C+ G C H+ G+ H G F
Sbjct: 88 IGDRAGIKLINANCLN--------------CEYCKTGHEPLCDHIQNYGIDRH-GTFQEY 132
Query: 150 XXXXXXXXXXIPNTLPLDVAALVEPISV-SWHAVRISKLQKGQSALVLGAGPIGLATILA 208
+ N L AA V V ++ +++ + ++ GQ ++ GAG GL +
Sbjct: 133 LTIRDIDAIKVSNDTNLAAAAPVLCGGVTAYKSLKATNVKPGQIVVLTGAGG-GLGSFGI 191
Query: 209 LQGHGASKIVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNILKKLAPGGEGFDFAYDCS 268
VV+ + + LG E F + D V ++KL GG ++ +
Sbjct: 192 QYAKAMGMRVVAVDHISKEDHCRNLGAEWFVDAFDTPDIVAHIRKLTNGGAHGVVSF--A 249
Query: 269 GVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSMCYTIKDFEDVVQ 328
K + + RG V + + I + + E V GS+ + D ++ +
Sbjct: 250 AAKKPMEYALEYVRKRGTVVFVGLPKDGTIPLDTLSLICNEITVKGSIVGSRMDVDEAID 309
Query: 329 ALGNG----SIAIDKARHLITGRQKIEDG 353
+ G I + K + + Q+++DG
Sbjct: 310 FITRGIVHVPIELVKLEDVPSVYQRMKDG 338
>YMR303c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 50.1 bits (118), Expect = 6e-06
Identities = 58/261 (22%), Positives = 103/261 (39%), Gaps = 33/261 (12%)
Query: 2 RALAYFGKQDIRYTKDLEEPVIETDDGIEIEVSWCGICGSDLHEYL-DGPIFFPEDGKVH 60
+A+ ++ KD+ P + ++ + I V + G+C +DLH + D P+
Sbjct: 8 KAIIFYESNGKLEHKDIPVPKPKPNE-LLINVKYSGVCHTDLHAWHGDWPL--------- 57
Query: 61 DVSGLGLPQAMGHEMSGIVSKVGPKVTNIKAGDHVVVE-ATGTCLDHYTWPNXXXXXXXX 119
LP GHE +G+V +G V K GD+ ++ G+C+
Sbjct: 58 ---PTKLPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCM--------------A 100
Query: 120 XXXCQRGFYNCCAHLGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPL-DVAALVEPISVS 178
C+ G + C H G H G F IP L +VA ++
Sbjct: 101 CEYCELGNESNCPHADLSGY-THDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGITV 159
Query: 179 WHAVRISKLQKGQSALVLG-AGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVET 237
+ A++ + L+ G A + G AG +G + + G +++ + + LG E
Sbjct: 160 YKALKSANLRAGHWAAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGPGKEELFTSLGGEV 218
Query: 238 FDPSEHKEDAVNILKKLAPGG 258
F ++D V+ + K GG
Sbjct: 219 FIDFTKEKDIVSAVVKATNGG 239
>YOL086c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 49.3 bits (116), Expect = 1e-05
Identities = 56/247 (22%), Positives = 96/247 (38%), Gaps = 33/247 (13%)
Query: 16 KDLEEPVIETDDGIEIEVSWCGICGSDLHEYL-DGPIFFPEDGKVHDVSGLGLPQAMGHE 74
KD+ P + ++ + I V + G+C +DLH + D P+ + LP GHE
Sbjct: 22 KDIPVPKPKANE-LLINVKYSGVCHTDLHAWHGDWPL------------PVKLPLVGGHE 68
Query: 75 MSGIVSKVGPKVTNIKAGDHVVVE-ATGTCLDHYTWPNXXXXXXXXXXXCQRGFYNCCAH 133
+G+V +G V K GD+ ++ G+C+ C+ G + C H
Sbjct: 69 GAGVVVGMGENVKGWKIGDYAGIKWLNGSCM--------------ACEYCELGNESNCPH 114
Query: 134 LGFMGLGVHSGGFAXXXXXXXXXXXXIPNTLPL-DVAALVEPISVSWHAVRISKLQKGQS 192
G H G F IP L VA ++ + A++ + L G
Sbjct: 115 ADLSGY-THDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSANLMAGHW 173
Query: 193 ALVLG-AGPIGLATILALQGHGASKIVVSEPAEIRRNQAAKLGVETFDPSEHKEDAVNIL 251
+ G AG +G + + G +++ + E + +G E F ++D V +
Sbjct: 174 VAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTKEKDIVGAV 232
Query: 252 KKLAPGG 258
K GG
Sbjct: 233 LKATDGG 239
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.139 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,145,329
Number of Sequences: 60738
Number of extensions: 997837
Number of successful extensions: 2173
Number of sequences better than 1.0e-05: 38
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2093
Number of HSP's gapped (non-prelim): 43
length of query: 385
length of database: 30,389,216
effective HSP length: 108
effective length of query: 277
effective length of database: 23,829,512
effective search space: 6600774824
effective search space used: 6600774824
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)