ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0151 good E KOG2250 Amino acid transport and metabolism Glutamate/leucine/phenylalanine/valine dehydrogenases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0151 46690 45308 -461
(461 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YAL062w [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehyd... 667 0.0
YOR375c [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehyd... 666 0.0
SPCC622.12c [E] KOG2250 Glutamate/leucine/phenylalanine/valine d... 486 e-137
At1g51720 [E] KOG2250 Glutamate/leucine/phenylalanine/valine deh... 305 7e-83
At5g18170 [E] KOG2250 Glutamate/leucine/phenylalanine/valine deh... 168 2e-41
At5g07440 [E] KOG2250 Glutamate/leucine/phenylalanine/valine deh... 166 7e-41
At3g03910 [E] KOG2250 Glutamate/leucine/phenylalanine/valine deh... 166 7e-41
Hs6912392 [E] KOG2250 Glutamate/leucine/phenylalanine/valine deh... 133 5e-31
Hs4885281 [E] KOG2250 Glutamate/leucine/phenylalanine/valine deh... 132 1e-30
7300986 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehyd... 125 1e-28
7301074 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehyd... 122 1e-27
CE06652 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehyd... 115 1e-25
>YAL062w [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 457
Score = 667 bits (1721), Expect = 0.0
Identities = 329/455 (72%), Positives = 375/455 (82%), Gaps = 1/455 (0%)
Query: 7 EPEFQQAYNEVYNCLKDSTLFDXXXXXXXXXXXXXXXERIIQFRVTWENDKGEQEVATGF 66
EPEFQQAY+E+ + ++DS +F+ ERIIQFRVTWEND GEQEVA G+
Sbjct: 4 EPEFQQAYDEIVSSVEDSKIFEKFPQYKKVLPIVSVPERIIQFRVTWENDNGEQEVAQGY 63
Query: 67 RVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLSLGGAKGGLCFDPKGRSD 126
RVQFNSAKGPYKGGLRFHP+VNLS+LKFLGFEQIFKNALTGL +GG KGGLC D KG+SD
Sbjct: 64 RVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDLKGKSD 123
Query: 127 SEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGYLFGAYRHYKNSWEGVLTGKDLN 186
+EIRR+CYAFM+ELSRHIG+D DVPAGDI VGGREIGYLFGAYR YKNSWEGVLTGK LN
Sbjct: 124 NEIRRICYAFMRELSRHIGKDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLN 183
Query: 187 WGGSLIRPEATGYGLIYYTEAMIKYASQGKESFEGKRVVISGSGNVAQYAALKCIELGAT 246
WGGSLIRPEATG+GL+YYT+AMI YA+ GKESFEGKRV ISGSGNVAQYAALK IELG
Sbjct: 184 WGGSLIRPEATGFGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGI 243
Query: 247 VLSLSDSKGSVISETGITAEHIYAIQDGRAAWKTLEQIVGEASVFSGSSVKYIAGARPWV 306
V+SLSDSKG +ISETGIT+E I+ I + +K+LE+IV E S FS S +KY+AGARPW
Sbjct: 244 VVSLSDSKGCIISETGITSEQIHDIASAKIRFKSLEEIVDEYSTFSESKMKYVAGARPWT 303
Query: 307 HVGKVDVALPCATQNEVSGAEAEHLVANGVKFVAEGSNMGSTQEAIDVFEGVRLQTASAS 366
HV VD+ALPCATQNEVSG EA+ LVA+GVKFVAEG+NMGST EAI VFE R TA+ +
Sbjct: 304 HVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETAR-STATNA 362
Query: 367 APAVWYAPGKASNMGGVAVSGLEMAQNSARVSWTRETVDAELKKIMTTCFDDCVTTAKEY 426
AVW+ P KA+N+GGVAVSGLEMAQNS +V+WT E VD ELKKIM CF+DC+ A+EY
Sbjct: 363 KDAVWFGPPKAANLGGVAVSGLEMAQNSQKVTWTAERVDQELKKIMINCFNDCIQAAQEY 422
Query: 427 SNESNVEALPSLVKGANLTGFIRVADAMLHQGDVF 461
S E N LPSLVKGAN+ F+ VADAML QGDVF
Sbjct: 423 STEKNTNTLPSLVKGANIASFVMVADAMLDQGDVF 457
>YOR375c [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 454
Score = 666 bits (1718), Expect = 0.0
Identities = 332/455 (72%), Positives = 376/455 (81%), Gaps = 3/455 (0%)
Query: 7 EPEFQQAYNEVYNCLKDSTLFDXXXXXXXXXXXXXXXERIIQFRVTWENDKGEQEVATGF 66
EPEFQQAY EV + L+DSTLF+ ERIIQFRVTWENDKGEQEVA G+
Sbjct: 3 EPEFQQAYEEVVSSLEDSTLFEQHPEYRKVLPIVSVPERIIQFRVTWENDKGEQEVAQGY 62
Query: 67 RVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLSLGGAKGGLCFDPKGRSD 126
RVQ+NSAKGPYKGGLRFHP+VNLS+LKFLGFEQIFKN+LTGL +GG KGGLC D KGRS+
Sbjct: 63 RVQYNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNSLTGLDMGGGKGGLCVDLKGRSN 122
Query: 127 SEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGYLFGAYRHYKNSWEGVLTGKDLN 186
+EIRR+CYAFM+ELSRHIGQD DVPAGDI VGGREIGYLFGAYR YKNSWEGVLTGK LN
Sbjct: 123 NEIRRICYAFMRELSRHIGQDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLN 182
Query: 187 WGGSLIRPEATGYGLIYYTEAMIKYASQGKESFEGKRVVISGSGNVAQYAALKCIELGAT 246
WGGSLIRPEATGYGL+YYT+AMI YA+ GKESFEGKRV ISGSGNVAQYAALK IELG T
Sbjct: 183 WGGSLIRPEATGYGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGT 242
Query: 247 VLSLSDSKGSVISETGITAEHIYAIQDGRAAWKTLEQIVGEASVFSGSSVKYIAGARPWV 306
V+SLSDSKG +ISETGIT+E + I + +K+LEQIV E S FS + V+YIAGARPW
Sbjct: 243 VVSLSDSKGCIISETGITSEQVADISSAKVNFKSLEQIVNEYSTFSENKVQYIAGARPWT 302
Query: 307 HVGKVDVALPCATQNEVSGAEAEHLVANGVKFVAEGSNMGSTQEAIDVFEGVRLQTASAS 366
HV KVD+ALPCATQNEVSG EA+ LVA GVKF+AEGSNMGST EAI VFE R TA+
Sbjct: 303 HVQKVDIALPCATQNEVSGEEAKALVAQGVKFIAEGSNMGSTPEAIAVFETAR-STATGP 361
Query: 367 APAVWYAPGKASNMGGVAVSGLEMAQNSARVSWTRETVDAELKKIMTTCFDDCVTTAKEY 426
+ AVWY P KA+N+GGVAVSGLEMAQNS R++WT E VD ELK+IM CF++C+ AK+Y
Sbjct: 362 SEAVWYGPPKAANLGGVAVSGLEMAQNSQRITWTSERVDQELKRIMINCFNECIDYAKKY 421
Query: 427 SNESNVEALPSLVKGANLTGFIRVADAMLHQGDVF 461
+ + V LPSLVKGAN+ FI+V+DAM QGDVF
Sbjct: 422 TKDGKV--LPSLVKGANIASFIKVSDAMFDQGDVF 454
>SPCC622.12c [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 451
Score = 486 bits (1250), Expect = e-137
Identities = 256/457 (56%), Positives = 320/457 (70%), Gaps = 13/457 (2%)
Query: 5 PYEPEFQQAYNEVYNCLKDSTLFDXXXXXXXXXXXXXXXERIIQFRVTWENDKGEQEVAT 64
PYEPEFQQAY E+ ++ S LF+ ER+++FRVTWE+DKG V T
Sbjct: 4 PYEPEFQQAYKEIVGSIESSKLFEVHPELKRVLPIISIPERVLEFRVTWEDDKGNCRVNT 63
Query: 65 GFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLSLGGAKGGLCFDPKGR 124
G+RVQFNSA GPYKGGLRFHP+VNLS+LKFLGFEQIFKNALTGL +GG KGG FDPKG+
Sbjct: 64 GYRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLPMGGGKGGSDFDPKGK 123
Query: 125 SDSEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGYLFGAYRHYKNSWEGVLTGKD 184
SD+EIRR AFM++L R+IG DVPAGDI V G + ++FG Y+ +N + GV+TGK
Sbjct: 124 SDNEIRRFSQAFMRQLFRYIGPQTDVPAGDIGVTGFVVMHMFGEYKRLRNEYSGVVTGKH 183
Query: 185 LNWGGSLIRPEATGYGLIYYTEAMIKYASQGKESFEGKRVVISGSGNVAQYAALKCIELG 244
+ GGS IRPEATGYG++YY + MI++ ++G E+ +GKRV ISGSGNVAQYAALKCI+ G
Sbjct: 184 MLTGGSNIRPEATGYGVVYYVKHMIEHRTKGAETLKGKRVAISGSGNVAQYAALKCIQEG 243
Query: 245 ATVLSLSDSKGSVISET--GITAEHIYAIQDGRAAWKTLEQIVGEASVFSGSSVKYIAGA 302
A V S+SDSKG +I++T G+ E I+ I A + I AS+ YIAGA
Sbjct: 244 AIVKSISDSKGVLIAKTAEGLVPEEIHEIM---ALKEKRASIADSASLC--KKHHYIAGA 298
Query: 303 RPWVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVAEGSNMGSTQEAIDVFEGVRLQT 362
RPW +VG++D+ALPCATQNEVSG EA L+ G ++VAEGSNMGS+ EA++VFE R
Sbjct: 299 RPWTNVGEIDIALPCATQNEVSGEEAAALIKQGCRYVAEGSNMGSSAEAVEVFEKSR--- 355
Query: 363 ASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWTRETVDAELKKIMTTCFDDCVTT 422
AS W APGKA+N GGVAVSGLEMAQN+ +WT VDA+L IM F+
Sbjct: 356 --ASGEGCWLAPGKAANAGGVAVSGLEMAQNAQFSTWTHAEVDAKLAGIMQNIFEQSTDV 413
Query: 423 AKEYSNESNVEALPSLVKGANLTGFIRVADAMLHQGD 459
A +Y +S +PSLV GAN+ GF++VA AM GD
Sbjct: 414 ASKYC-DSGSNNIPSLVDGANIAGFLKVATAMQAVGD 449
>At1g51720 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 624
Score = 305 bits (782), Expect = 7e-83
Identities = 172/460 (37%), Positives = 259/460 (55%), Gaps = 24/460 (5%)
Query: 1 MSAEPYEPEFQQAYNEVYNCLKDSTLFDXXXXXXXXXXXXXXXERIIQFRVTWENDKGEQ 60
+ +P E EF Q+ E + L+ + ER+I FRV W +D+GE
Sbjct: 189 LKRDPNEIEFVQSVQESVHALE--RVIAKNSHYVNIMERLLEPERMIVFRVPWIDDRGET 246
Query: 61 EVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLSLGGAKGGLCFD 120
V GFRVQFN A GP +GG+RFHP++NLS+ KFLGF+Q KNAL+ LGGA GG FD
Sbjct: 247 HVNRGFRVQFNQALGPCRGGIRFHPSMNLSIAKFLGFQQTLKNALSPYKLGGASGGSDFD 306
Query: 121 PKGRSDSEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGYLFGAYRHYKNSWEGVL 180
PKG+SD+EI R C +FM E+ R++G D D+P+ ++ VG RE+GYLFG YR ++G
Sbjct: 307 PKGKSDNEIMRFCQSFMNEMYRYMGPDKDLPSEEVGVGTREMGYLFGQYRRLAGQFQGSF 366
Query: 181 TGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQGKESFEGKRVVISGSGNVAQYAALKC 240
TG + W S +R EA+GYG++Y+ ++ A KE +G R V+SG G +A + K
Sbjct: 367 TGPRIYWAASSLRTEASGYGVVYFARLIL--ADMNKE-IKGLRCVVSGCGKIAMHVVEKL 423
Query: 241 IELGATVLSLSDSKGSVISETGITAEHIYAIQDGRAAWKTLEQIVGEASVFSGSSVKYIA 300
I GA +++SDSKG ++ + G + ++D ++ ++L + + KY
Sbjct: 424 IACGAHPVTVSDSKGYLVDDDGFDYMKLAFLRDIKSQQRSLRDYSK-----TYARAKYFD 478
Query: 301 GARPWVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVAEGSNMGSTQEAIDVFEGVRL 360
+PW + DVA PCA+QNEV A+A +LV G + + EGSNM T EA+DVF
Sbjct: 479 ELKPWNE--RCDVAFPCASQNEVDQADAINLVNAGCRLLVEGSNMPCTAEAVDVFRKAN- 535
Query: 361 QTASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWTRETVDAELKKIMTTCFDDCV 420
V AP A+ GGVA +E+ + S + W+ E ++ L++ + ++ +
Sbjct: 536 ---------VLIAPAIAAGAGGVAAGEIEVLRESNSMQWSAEDFESRLQEALKQTYEKAL 586
Query: 421 TTAKEYSNESNVEALPSLVKGANLTGFIRVADAMLHQGDV 460
A ++ + E+ +L+ GA + F+ +A AM QG V
Sbjct: 587 KAANDFGYQK--ESPEALLHGATIAAFLNIAQAMTDQGCV 624
>At5g18170 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 411
Score = 168 bits (425), Expect = 2e-41
Identities = 131/418 (31%), Positives = 196/418 (46%), Gaps = 46/418 (11%)
Query: 45 RIIQFRVTWENDKGEQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNA 104
R I+ T D G GFRVQ ++A+GP KGG+R+HP V+ + L +K A
Sbjct: 33 REIKVECTIPKDDGTLASFVGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTA 92
Query: 105 LTGLSLGGAKGGLCFDPKGRSDSEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGY 164
+ + GGAKGG+ DP S SE+ R+ F +++ IG DVPA D+ G + + +
Sbjct: 93 VAKIPYGGAKGGIGCDPSKLSISELERLTRVFTQKIHDLIGIHTDVPAPDMGTGPQTMAW 152
Query: 165 LFGAYRHYKNSWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQGKESFEGKRV 224
+ Y + V+TGK ++ GGSL R ATG G+++ TEA++ ++ ++ G+R
Sbjct: 153 ILDEYSKFHGYSPAVVTGKPIDLGGSLGRDAATGRGVMFGTEALL---NEHGKTISGQRF 209
Query: 225 VISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHIYAIQDGRAAWKTLEQI 284
VI G GNV +AA E G ++++SD G++ ++ GI D A K ++
Sbjct: 210 VIQGFGNVGSWAAKLISEKGGKIVAVSDITGAIKNKDGI---------DIPALLKHTKEH 260
Query: 285 VGEASVFSGSSVKYIAGARP----WVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVA 340
G VK GA P + V D+ +P A ++ A + A KF+
Sbjct: 261 RG---------VKGFDGADPIDPNSILVEDCDILVPAALGGVINRENANEIKA---KFII 308
Query: 341 EGSNMGSTQEAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWT 400
E +N + +A ++ S V P +N GGV VS E QN W
Sbjct: 309 EAANHPTDPDADEIL----------SKKGVVILPDIYANSGGVTVSYFEWVQNIQGFMWE 358
Query: 401 RETVDAELKKIMTTCFDDCVTTAKEYSNESNVEALPSLVKGANLTGFIRVADAMLHQG 458
E V+ ELK MT F D K +S + L GA G RVA A + +G
Sbjct: 359 EEKVNDELKTYMTRSFKDLKEMCKTHSCD--------LRMGAFTLGVNRVAQATILRG 408
>At5g07440 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 411
Score = 166 bits (420), Expect = 7e-41
Identities = 129/414 (31%), Positives = 193/414 (46%), Gaps = 38/414 (9%)
Query: 45 RIIQFRVTWENDKGEQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNA 104
R I+ T D G GFRVQ ++A+GP KGG+R+HP V+ + L +K A
Sbjct: 33 REIKVECTIPKDDGTLVSYIGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTA 92
Query: 105 LTGLSLGGAKGGLCFDPKGRSDSEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGY 164
+ + GGAKGG+ P+ S SE+ R+ F +++ IG DVPA D+ + + +
Sbjct: 93 VADIPYGGAKGGIGCSPRDLSLSELERLTRVFTQKIHDLIGIHTDVPAPDMGTNAQTMAW 152
Query: 165 LFGAYRHYKNSWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQGKESFEGKRV 224
+ Y + V+TGK ++ GGSL R ATG G+++ TEA++ A GK S +G
Sbjct: 153 ILDEYSKFHGHSPAVVTGKPIDLGGSLGREAATGRGVVFATEALL--AEYGK-SIQGLTF 209
Query: 225 VISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHIYAIQDGRAAWKTLEQI 284
VI G GNV +AA E G V+++SD G++ + GI + +D
Sbjct: 210 VIQGFGNVGTWAAKLIHEKGGKVVAVSDITGAIRNPEGIDINALIKHKDA---------- 259
Query: 285 VGEASVFSGSSVKYIAGARPWVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVAEGSN 344
G + F+G A + + + DV +PCA ++ A + A KF+ E +N
Sbjct: 260 TGSLNDFNGGD----AMNSDELLIHECDVLIPCALGGVLNKENAGDVKA---KFIVEAAN 312
Query: 345 MGSTQEAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWTRETV 404
+ +A ++ S V P +N GGV VS E QN W E V
Sbjct: 313 HPTDPDADEIL----------SKKGVIILPDIYANAGGVTVSYFEWVQNIQGFMWEEEKV 362
Query: 405 DAELKKIMTTCFDDCVTTAKEYSNESNVEALPSLVKGANLTGFIRVADAMLHQG 458
+ EL+K MT F + T +S +L GA G RVA A +G
Sbjct: 363 NLELQKYMTRAFHNIKTMCHTHS--------CNLRMGAFTLGVNRVARATQLRG 408
>At3g03910 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 411
Score = 166 bits (420), Expect = 7e-41
Identities = 124/414 (29%), Positives = 193/414 (45%), Gaps = 38/414 (9%)
Query: 45 RIIQFRVTWENDKGEQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNA 104
R I+ T D G GFRVQ ++A+GP KGG+R+HP V + L +K A
Sbjct: 33 REIKVECTIPKDDGTLASFVGFRVQHDNARGPMKGGIRYHPEVEPDEVNALAQLMTWKTA 92
Query: 105 LTGLSLGGAKGGLCFDPKGRSDSEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGY 164
+ + GGAKGG+ DP S SE+ R+ F +++ IG DVPA D+ G + + +
Sbjct: 93 VAKIPYGGAKGGIGCDPSELSLSELERLTRVFTQKIHDLIGIHTDVPAPDMGTGPQTMAW 152
Query: 165 LFGAYRHYKNSWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQGKESFEGKRV 224
+ Y + V+TGK ++ GGSL R ATG G+++ TEA++ ++ ++ G+R
Sbjct: 153 ILDEYSKFHGHSPAVVTGKPIDLGGSLGRDAATGRGVLFATEALL---NEHGKTISGQRF 209
Query: 225 VISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHIYAIQDGRAAWKTLEQI 284
I G GNV +AA + G ++++SD G++ + GI I ++ + + ++
Sbjct: 210 AIQGFGNVGSWAAKLISDKGGKIVAVSDVTGAIKNNNGI---DILSLLEHAEENRGIKGF 266
Query: 285 VGEASVFSGSSVKYIAGARPWVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVAEGSN 344
G S+ S + V D+ +P A ++ A + A KF+ EG+N
Sbjct: 267 DGADSIDPDS-----------ILVEDCDILVPAALGGVINRENANEIKA---KFIIEGAN 312
Query: 345 MGSTQEAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWTRETV 404
+ EA ++ + V P +N GGV VS E QN W E V
Sbjct: 313 HPTDPEADEILK----------KKGVMILPDIYANSGGVTVSYFEWVQNIQGFMWDEEKV 362
Query: 405 DAELKKIMTTCFDDCVTTAKEYSNESNVEALPSLVKGANLTGFIRVADAMLHQG 458
+ ELK MT F D + +S + L GA G RVA A +G
Sbjct: 363 NRELKTYMTRGFKDLKEMCQTHSCD--------LRMGAFTLGINRVAQATTIRG 408
>Hs6912392 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 558
Score = 133 bits (335), Expect = 5e-31
Identities = 107/367 (29%), Positives = 173/367 (46%), Gaps = 47/367 (12%)
Query: 56 DKGEQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLSLGGAKG 115
D G EV G+R Q + + P KGG+R+ V++ +K L +K A+ + GGAK
Sbjct: 125 DDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKA 184
Query: 116 GLCFDPKGRSDSEIRRVCYAFMKELSR--HIGQDVDVPAGDIQVGGREIGYLFGAYR--- 170
G+ +PK +++E+ ++ F EL++ IG VDVPA D+ G RE+ ++ Y
Sbjct: 185 GVKINPKNYTENELEKITRRFTMELAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTI 244
Query: 171 -HYKNSWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQGK-----ESFEGKRV 224
HY + +TGK ++ GG R ATG G+ + E I AS F K
Sbjct: 245 GHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINQASYMSILGMTPGFRDKTF 304
Query: 225 VISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHI--YAIQDGRAAWKTLE 282
V+ G GNV ++ GA +++ +S GS+ + GI + + + +Q G
Sbjct: 305 VVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHG-------- 356
Query: 283 QIVG--EASVFSGSSVKYIAGARPWVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVA 340
I+G +A + GS ++ D+ +P AT+ +++ + A + A K +A
Sbjct: 357 SILGFPKAKPYEGSILEV-----------DCDILIPAATEKQLTKSNAPRVKA---KIIA 402
Query: 341 EGSNMGSTQEAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWT 400
EG+N +T EA +F L+ P ++ N GGV VS E +N VS+
Sbjct: 403 EGANGPTTPEADKIF----LERNILVIPDLYL------NAGGVTVSYFEWLKNLNHVSYG 452
Query: 401 RETVDAE 407
R T E
Sbjct: 453 RLTFKYE 459
>Hs4885281 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 558
Score = 132 bits (332), Expect = 1e-30
Identities = 105/367 (28%), Positives = 170/367 (45%), Gaps = 47/367 (12%)
Query: 56 DKGEQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLSLGGAKG 115
D G EV G+R Q + + P KGG+R+ V++ +K L +K A+ + GGAK
Sbjct: 125 DDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKA 184
Query: 116 GLCFDPKGRSDSEIRRVCYAFMKELSR--HIGQDVDVPAGDIQVGGREIGYLFGAYR--- 170
G+ +PK +D+E+ ++ F EL++ IG +DVPA D+ G RE+ ++ Y
Sbjct: 185 GVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTI 244
Query: 171 -HYKNSWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQGK-----ESFEGKRV 224
HY + +TGK ++ GG R ATG G+ + E I AS F K
Sbjct: 245 GHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTF 304
Query: 225 VISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHI--YAIQDGRAAWKTLE 282
V+ G GNV ++ GA +++ +S GS+ + GI + + + +Q G
Sbjct: 305 VVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHG-------- 356
Query: 283 QIVG--EASVFSGSSVKYIAGARPWVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVA 340
I+G +A + GS ++ D+ +P A++ +++ + A + A K +A
Sbjct: 357 SILGFPKAKPYEGSILE-----------ADCDILIPAASEKQLTKSNAPRVKA---KIIA 402
Query: 341 EGSNMGSTQEAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWT 400
EG+N +T EA +F + P N GGV VS E +N VS+
Sbjct: 403 EGANGPTTPEADKIF----------LERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYG 452
Query: 401 RETVDAE 407
R T E
Sbjct: 453 RLTFKYE 459
>7300986 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 520
Score = 125 bits (315), Expect = 1e-28
Identities = 103/366 (28%), Positives = 173/366 (47%), Gaps = 45/366 (12%)
Query: 47 IQFRVTWENDKGEQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALT 106
+ F + +N G E+ +G+R + P KGG+R+ VN S +K L FK A
Sbjct: 82 VNFPIVRKN--GTYEIISGYRSHHVRHRLPLKGGIRYALDVNESEVKALAAIMTFKCACV 139
Query: 107 GLSLGGAKGGLCFDPKGRSDSEIRRVCYAFMKELSRH--IGQDVDVPAGDIQVGGREIGY 164
+ GG+KGG+C DPK + E++ + + EL + IG +DVPA D+ G RE+ +
Sbjct: 140 NVPYGGSKGGICIDPKKYTVDELQTITRRYTMELLKRNMIGPGIDVPAPDVNTGPREMSW 199
Query: 165 LFGAYRH---YKN-SWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYAS-----QG 215
+ Y+ YK+ + ++TGK ++ GG R ATG G+ + +K +
Sbjct: 200 IVDQYQKTFGYKDINSSAIVTGKPVHNGGINGRHSATGRGVWKAGDLFLKDKEWMDLLKW 259
Query: 216 KESFEGKRVVISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHIYAIQDGR 275
K ++ K V++ G GNV +AA E GA V+ + + S++++ GI ++ + +
Sbjct: 260 KTGWKDKTVIVQGFGNVGSFAAKYVHEAGAKVIGIKEFDVSLVNKDGIDINDLFEYTEEK 319
Query: 276 AAWKTLEQIVGEASVFSGSSVKYIAGARPWVHVGKVDVALPCATQNEVSGAEAEHLVANG 335
KT++ ++ + V + D+ +PCATQ ++ A+ + A
Sbjct: 320 ---KTIK------------GYPKAQESKEDLLVAETDILMPCATQKVITTDNAKDIKA-- 362
Query: 336 VKFVAEGSNMGSTQ--EAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVSGLEMAQN 393
K + EG+N +T E I + +GV L P N GGV VS E +N
Sbjct: 363 -KLILEGANGPTTPSGEKILLDKGVLL------------VPDLYCNAGGVTVSYFEYLKN 409
Query: 394 SARVSW 399
VS+
Sbjct: 410 INHVSY 415
>7301074 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 590
Score = 122 bits (306), Expect = 1e-27
Identities = 112/381 (29%), Positives = 165/381 (42%), Gaps = 48/381 (12%)
Query: 44 ERIIQFRVTWENDKGEQEVATGFRVQFNSAKGPYKGG--LRFHPTVNLSVLKFLGFEQIF 101
+ II+ D G E+ TG+R Q ++ K P KGG +RF V+ +K L F
Sbjct: 104 DHIIEIAFPLRRDAGNYEMITGYRAQHSTHKTPTKGGKCIRFSLDVSRDEVKALSALMTF 163
Query: 102 KNALTGLSLGGAKGGLCFDPKGRSDSEIRRVCYAFMKELSR--HIGQDVDVPAGDIQVGG 159
K A + GGAK GL +PK S+ E+ ++ F EL++ IG VDVPA D+ G
Sbjct: 164 KCACVDVPFGGAKAGLKINPKEYSEHELEKITRRFTLELAKKGFIGPGVDVPAPDMGTGE 223
Query: 160 REIGYLFGAYR----HYKNSWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQG 215
RE+ ++ Y H + +TGK +N GG R ATG G+ + E I A+
Sbjct: 224 REMSWIADTYAKTIGHLDINAHACVTGKPINQGGIHGRVSATGRGVFHGLENFINEANYM 283
Query: 216 KE-----SFEGKRVVISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHIYA 270
+ + GK ++ G GNV + GAT + + + G++ + GI
Sbjct: 284 SQIGTTPGWGGKTFIVQGFGNVGLHTTRYLTRAGATCIGVIEHDGTLYNPEGIDP----- 338
Query: 271 IQDGRAAWKTLEQIVGEASVFSGSSVKYIAGARPW----VHVGKVDVALPCATQNEVSGA 326
K LE E G+ V Y A+P+ + K D+ +P A + ++
Sbjct: 339 --------KLLEDYKNE----HGTIVGY-QNAKPYEGENLMFEKCDIFIPAAVEKVITSE 385
Query: 327 EAEHLVANGVKFVAEGSNMGSTQEAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVS 386
A + A K +AE +N G T A D R + P N GGV VS
Sbjct: 386 NANRIQA---KIIAEAAN-GPTTPAADKILIDR---------NILVIPDLYINAGGVTVS 432
Query: 387 GLEMAQNSARVSWTRETVDAE 407
E +N VS+ R T E
Sbjct: 433 FFEWLKNLNHVSYGRLTFKYE 453
>CE06652 [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
Length = 536
Score = 115 bits (289), Expect = 1e-25
Identities = 116/405 (28%), Positives = 173/405 (42%), Gaps = 45/405 (11%)
Query: 56 DKGEQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLSLGGAKG 115
D GE EV +R Q + + P KGG+R+ V +K L +K A+ + GGAKG
Sbjct: 103 DNGEFEVIEAWRAQHSEHRTPTKGGIRYSLDVCEDEVKALSALMTYKCAVVDVPFGGAKG 162
Query: 116 GLCFDPKGRSDSEI----RRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGYLFGAYR- 170
G+ DPK +D EI RR+ F K+ +G VDVPA D+ G RE+G++ Y
Sbjct: 163 GVKIDPKQYTDYEIEKITRRIAIEFAKK--GFLGPGVDVPAPDMGTGEREMGWIADTYAQ 220
Query: 171 ---HYKNSWEGVLTGKDLNWGGSLIRPEATGYGLIYYTEAMIKYASQGK-----ESFEGK 222
H +TGK + GG R ATG G+ E A K GK
Sbjct: 221 TIGHLDRDASACITGKPIVSGGIHGRVSATGRGVWKGLEVFTNDADYMKMVGLDTGLAGK 280
Query: 223 RVVISGSGNVAQYAALKCIELGATVLSLSDSKGSVISETGITAEHIYAIQDGRAAWKTLE 282
+I G GNV + G+ V+ + + +V + GI H ++D + A T++
Sbjct: 281 TAIIQGFGNVGLHTHRYLHRAGSKVIGIQEYDCAVYNPDGI---HPKELEDWKDANGTIK 337
Query: 283 QIVGEASVFSGSSVKYIAGARPWVHVGKVDVALPCATQNEVSGAEAEHLVANGVKFVAEG 342
G + + + Y K D+ +P A + + A + A K +AE
Sbjct: 338 NFPGAKNFDPFTELMY----------EKCDIFVPAACEKSIHKENASRIQA---KIIAEA 384
Query: 343 SNMGSTQEAIDVFEGVRLQTASASAPAVWYAPGKASNMGGVAVSGLEMAQNSARVSWTRE 402
+N G T A D R+ A + P N GGV VS E +N VS+ R
Sbjct: 385 AN-GPTTPAAD-----RILLARGDCLII---PDMYVNSGGVTVSYFEWLKNLNHVSYGRL 435
Query: 403 T--VDAELKKIMTTCFDDCVTTA--KEYSNESNVEALPSLVKGAN 443
T D E K++ + ++ A K+ E N A + + GA+
Sbjct: 436 TFKYDEEANKMLLASVQESLSKAVGKDCPVEPNA-AFAAKIAGAS 479
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,842,173
Number of Sequences: 60738
Number of extensions: 1057721
Number of successful extensions: 2449
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2398
Number of HSP's gapped (non-prelim): 16
length of query: 461
length of database: 30,389,216
effective HSP length: 110
effective length of query: 351
effective length of database: 23,708,036
effective search space: 8321520636
effective search space used: 8321520636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)