ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0169 good CR KOG1198 Energy production and conversion Zinc-binding oxidoreductase
r_klactVI0169 good CR KOG1198 General function prediction only Zinc-binding oxidoreductase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0169 51849 52994 382
(382 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL134c [CR] KOG1198 Zinc-binding oxidoreductase 94 3e-19
YLR460c [CR] KOG1198 Zinc-binding oxidoreductase 94 3e-19
YCR102c [CR] KOG1198 Zinc-binding oxidoreductase 90 6e-18
SPAC2E1P3.01 [CR] KOG1198 Zinc-binding oxidoreductase 80 7e-15
At1g23740 [CR] KOG1198 Zinc-binding oxidoreductase 75 2e-13
Hs13236495 [CR] KOG1198 Zinc-binding oxidoreductase 74 3e-13
YBR046c [CR] KOG1197 Predicted quinone oxidoreductase 74 5e-13
SPBC16A3.02c [CR] KOG1198 Zinc-binding oxidoreductase 73 6e-13
SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase 72 1e-12
Hs18379349 [CR] KOG1197 Predicted quinone oxidoreductase 69 2e-11
YMR303c [Q] KOG0023 Alcohol dehydrogenase class V 65 2e-10
CE16009 [CR] KOG1198 Zinc-binding oxidoreductase 64 4e-10
At5g61510 [CR] KOG1197 Predicted quinone oxidoreductase 63 8e-10
YOL086c [Q] KOG0023 Alcohol dehydrogenase class V 62 2e-09
SPCC1442.16c [CR] KOG1197 Predicted quinone oxidoreductase 62 2e-09
YBR145w [Q] KOG0023 Alcohol dehydrogenase class V 61 2e-09
At4g13010 [CR] KOG1198 Zinc-binding oxidoreductase 61 2e-09
At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase 59 9e-09
At3g15090 [CR] KOG1198 Zinc-binding oxidoreductase 59 2e-08
CE19192 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 55 2e-07
YDL168w [Q] KOG0022 Alcohol dehydrogenase class III 54 4e-07
Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III 52 1e-06
YBL069w [CR] KOG1198 Zinc-binding oxidoreductase 51 2e-06
YER101c [CR] KOG1198 Zinc-binding oxidoreductase 50 6e-06
>YNL134c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 376
Score = 94.0 bits (232), Expect = 3e-19
Identities = 74/265 (27%), Positives = 126/265 (46%), Gaps = 32/265 (12%)
Query: 43 VPQTQKGLVVSSFTEDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIYSF 102
+P+T K +V+ + +K D+P+P+ L+ +LIK + N DWK ++
Sbjct: 5 IPETMKAVVIENGKAVVK--QDIPIPE-LEEGFVLIKTVAVAGNPTDWKHIDFKIGPQGA 61
Query: 103 PWVNGRESSGIVVRRGEKVDEEKFPLGGEVF--IASTTYRDLRTSTFQEYTVFDSRLVWR 160
+ G +++G +V+ G VD +F +G ++ I + R F EY+ S ++
Sbjct: 62 --LLGCDAAGQIVKLGPNVDAARFAIGDYIYGVIHGASVRFPSNGAFAEYSAISSETAYK 119
Query: 161 VPERI--------------GLDFASGIGVSLVTAGAALASKRNVKVQPEEKKS-----IV 201
L+ A + VSL TAG L + + + K+ I+
Sbjct: 120 PAREFRLCGKDKLPEGPVKSLEGAVSLPVSLTTAGMILTHSFGLDMTWKPSKAQRDQPIL 179
Query: 202 IWGGSTGVGIFVVQLAKSL-GFTKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNEIK 260
WGG+T VG ++QLAK L GF+KII + S+KHE+ L GA + + D++ +IK
Sbjct: 180 FWGGATAVGQMLIQLAKKLNGFSKIIVVASRKHEKLLKEYGADELFDYHD--ADVIEQIK 237
Query: 261 KICPNGVSHGVDLISKKTAETLSSI 285
K N + + VD +S ET+ +
Sbjct: 238 KKY-NNIPYLVDCVS--NTETIQQV 259
>YLR460c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 376
Score = 94.0 bits (232), Expect = 3e-19
Identities = 74/265 (27%), Positives = 129/265 (47%), Gaps = 32/265 (12%)
Query: 43 VPQTQKGLVVSSFTEDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIYSF 102
+P+T K +V+ +K +P+P+ L+ +LIK + N DW Y+
Sbjct: 5 IPETMKAVVIEDGKAVVK--EGIPIPE-LEEGFVLIKTLAVAGNPTDWAHIDYKIGPQGS 61
Query: 103 PWVNGRESSGIVVRRGEKVDEEKFPLGGEV--FIASTTYRDLRTSTFQEYTVFDSRLVWR 160
+ G +++G +V+ G V+ + F +G + FI ++ R F EY+ + + ++
Sbjct: 62 --ILGCDAAGQIVKLGPAVNPKDFSIGDYIYGFIHGSSVRFPSNGAFAEYSAISTVVAYK 119
Query: 161 VPERI--------------GLDFASGIGVSLVTAGAALASKRNVKVQ-----PEEKKSIV 201
P + L+ + I VSL TAG L + ++ P+ K I+
Sbjct: 120 SPNELKFLGEDVLPAGPVRSLEGVATIPVSLTTAGLVLTYNLGLDLKWEPSTPQRKGPIL 179
Query: 202 IWGGSTGVGIFVVQLAKSL-GFTKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNEIK 260
+WGG+T VG ++QLA L GFTKII + S+KHE+ L GA + + D+V +IK
Sbjct: 180 LWGGATAVGQSLIQLANKLNGFTKIIVVASRKHEKLLKEYGADELFDYHD--IDVVEQIK 237
Query: 261 KICPNGVSHGVDLISKKTAETLSSI 285
N +S+ VD ++ + +TL +
Sbjct: 238 HKY-NNISYLVDCVANQ--DTLQQV 259
>YCR102c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 368
Score = 89.7 bits (221), Expect = 6e-18
Identities = 68/235 (28%), Positives = 115/235 (48%), Gaps = 28/235 (11%)
Query: 65 LPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIYSFPWVNGRESSGIVVRRGEKVDEE 124
+P+P+ L+ +LIK + N DW Y+ + G +++G +V+ G VD +
Sbjct: 17 VPIPE-LEEGFVLIKTLAVAGNPTDWAHIDYKVGPQGS--ILGCDAAGQIVKLGPAVDPK 73
Query: 125 KFPLGGEV--FIASTTYRDLRTSTFQEYTVFDSRLVWRVPERI--------------GLD 168
F +G + FI ++ R F EY+ + + ++ P + L+
Sbjct: 74 DFSIGDYIYGFIHGSSVRFPSNGAFAEYSAISTVVAYKSPNELKFLGEDVLPAGPVRSLE 133
Query: 169 FASGIGVSLVTAGAALASKRNVKVQ-----PEEKKSIVIWGGSTGVGIFVVQLAKSL-GF 222
A+ I VSL TAG L + ++ P+ I++WGG+T VG ++QLA L GF
Sbjct: 134 GAATIPVSLTTAGLVLTYNLGLNLKWEPSTPQRNGPILLWGGATAVGQSLIQLANKLNGF 193
Query: 223 TKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNEIKKICPNGVSHGVDLISKK 277
TKII + S+KHE+ L GA + + D+V +IK N +S+ VD ++ +
Sbjct: 194 TKIIVVASRKHEKLLKEYGADQLFDYHD--IDVVEQIKHKY-NNISYLVDCVANQ 245
>SPAC2E1P3.01 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 348
Score = 79.7 bits (195), Expect = 7e-15
Identities = 92/357 (25%), Positives = 153/357 (42%), Gaps = 38/357 (10%)
Query: 51 VVSSFTEDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIYSFPWVNGRES 110
V++ +++++D P P K E L + + N +DWK+ Y SI V G +
Sbjct: 4 VIADGQNGVEVISDAPKPTPEKG-EFLGRVIRVAFNPIDWKTL-YNASIEKGT-VGGTDF 60
Query: 111 SGIVVRRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFA 170
+V GE VD K+ +G V + D + ++EY D LV+ VP+ I A
Sbjct: 61 VAVVEDVGEGVDRSKY-IGATVSGWAPGPLDGSNAAWREYITLDVNLVYFVPKNITPSQA 119
Query: 171 SGIGVSLVTAGAALASKRNVKVQPEE-------KKSIVIWGGSTGVGIFVVQLAKSLGFT 223
+ + ++ TA L + + P + +K +++W GS+ VG +VVQLA G+
Sbjct: 120 ATLPLTFTTASQGLNQYLGLPLPPTDGSKNSAQQKWVLVWSGSSSVGQYVVQLAHHAGY- 178
Query: 224 KIITITSKKHEQYLLSLGATHIIHREEKTEDIVNEIKKICPNGVSHGVDLISKKTAETLS 283
K+I S + ++ LGA + + ++V IKK + V +G D S TL+
Sbjct: 179 KVIATCSPHNFDWIKKLGADFTVDYHD--PNVVEIIKKATDDSVFYGFDAASFPETSTLA 236
Query: 284 ----SILSAESKLVCAAGCPNKAQVNDPTIKVEAINLKLFHEDL--------------DY 325
S + KL+ P + I + I+ LF+ + D+
Sbjct: 237 VKAFSSKVKDGKLINILSSPPSPRSEVKIIGI--IDYSLFNREFNFFGNKIEPIQASYDH 294
Query: 326 GQEFVRYTTELFEKNRLKPLSNLKLFKGLENFCQGIRNGLRELEERGASAEKYVVAI 382
E + T ++ + P + +K F G Q I LRE SA K+VV I
Sbjct: 295 AVEVYKKLTGWLQEGVIIP-NRVKEFDG---GLQAIPKALREFASGKHSAVKFVVRI 347
>At1g23740 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 386
Score = 74.7 bits (182), Expect = 2e-13
Identities = 68/223 (30%), Positives = 117/223 (51%), Gaps = 19/223 (8%)
Query: 43 VPQTQKGLVVSSF--TEDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIY 100
+P+ K V S + + LKL +++ VP+ +K ++LIK LN VD K ++ +F
Sbjct: 74 IPKEMKAWVYSDYGGVDVLKLESNIVVPE-IKEDQVLIKVVAAALNPVDAKRRQGKFKAT 132
Query: 101 S--FPWVNGRESSGIVVRRGEKVDEEKFPLGGEVFIASTTYRDL----RTSTFQEYTVFD 154
P V G + +G+VV+ G V + K G EV+ A+ + + L + + EYT +
Sbjct: 133 DSPLPTVPGYDVAGVVVKVGSAVKDLKE--GDEVY-ANVSEKALEGPKQFGSLAEYTAVE 189
Query: 155 SRLVWRVPERIGLDFASGIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVV 214
+L+ P+ I A+G+ +++ TA L V+ + KSI++ G+ GVG V+
Sbjct: 190 EKLLALKPKNIDFAQAAGLPLAIETADEGL-----VRTEFSAGKSILVLNGAGGVGSLVI 244
Query: 215 QLAKSL-GFTKIITITSKKHEQYLLSLGATHII-HREEKTEDI 255
QLAK + G +K+ S + + + SLGA I + +E ED+
Sbjct: 245 QLAKHVYGASKVAATASTEKLELVRSLGADLAIDYTKENIEDL 287
>Hs13236495 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 329
Score = 74.3 bits (181), Expect = 3e-13
Identities = 78/296 (26%), Positives = 134/296 (44%), Gaps = 24/296 (8%)
Query: 57 EDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIYSF-PWVNGRESSGIVV 115
E LKL +D+ VP K +++LIK G+N V+ + +S P+ G + +G++
Sbjct: 20 EVLKLRSDIAVPIP-KDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIE 78
Query: 116 RRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFASGIGV 175
G+ F G VF +ST + + EY + V+++PE++ + IG+
Sbjct: 79 AVGDNASA--FKKGDRVFTSSTI-----SGGYAEYALAADHTVYKLPEKLDFKQGAAIGI 131
Query: 176 SLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQ 235
TA AL VK +S+++ G S GVG+ Q+A++ G + T +++ ++
Sbjct: 132 PYFTAYRALIHSACVKAG----ESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
Query: 236 YLLSLGATHIIHREEKTEDIVNEIKKICPNGVSHGVDLISKKTAE-TLSSILS--AESKL 292
+L GA + + E VN I KI G+D+I + A LS LS +
Sbjct: 188 IVLQNGAHEVFNHRE-----VNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGR 242
Query: 293 VCAAGCPNKAQVND-PTIKVEA--INLKLFHEDLDYGQEFVRYTTELFEKNRLKPL 345
V G ++N T+ E+ I + LF + Q++ E LKP+
Sbjct: 243 VIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPV 298
>YBR046c [CR] KOG1197 Predicted quinone oxidoreductase
Length = 334
Score = 73.6 bits (179), Expect = 5e-13
Identities = 85/320 (26%), Positives = 144/320 (44%), Gaps = 29/320 (9%)
Query: 43 VPQTQKGLVVSSFTE-DLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIY- 100
+P+ QK +++ D+ D PVP + E+LIKNKY G+N+++ +R IY
Sbjct: 5 IPEQQKVILIDEIGGYDVIKYEDYPVPS-ISEEELLIKNKYTGVNYIE---SYFRKGIYP 60
Query: 101 -SFPWVNGRESSGIVVRRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSR-LV 158
P+V GRE+SG VV +G+ V F +G +V S STF +Y+ S+ V
Sbjct: 61 CEKPYVLGREASGTVVAKGKGV--TNFEVGDQVAYIS-------NSTFAQYSKISSQGPV 111
Query: 159 WRVPERIGLDFASGIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAK 218
++P+ + L+ AL S N ++ ++++ + GVG+ + QL K
Sbjct: 112 MKLPKGTSDEELKLYAAGLLQVLTAL-SFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLK 170
Query: 219 SLGFTKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNEIKKIC-PNGVSHGVDLISKK 277
G I ++ + + GA ++I+ + EDI+ ++ K GV D + K
Sbjct: 171 MKGAHTIAVASTDEKLKIAKEYGAEYLINASK--EDILRQVLKFTNGKGVDASFDSVGKD 228
Query: 278 TAETLSSILSAESKLVCAAGCPNKAQVNDPTIKVEAINLKLFHEDLDYG-----QEFVRY 332
T E + L + V T ++ N+ L L YG +E+ Y
Sbjct: 229 TFEISLAALKRKGVFVSFGNASGLIPPFSIT-RLSPKNITLVRPQL-YGYIADPEEWKYY 286
Query: 333 TTELFEKNRLKPLSNLKLFK 352
+ E F K L N+K++K
Sbjct: 287 SDEFFGLVNSKKL-NIKIYK 305
>SPBC16A3.02c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 347
Score = 73.2 bits (178), Expect = 6e-13
Identities = 60/205 (29%), Positives = 107/205 (51%), Gaps = 14/205 (6%)
Query: 65 LPVPQKLKPYEILIKNKYIGLNHVDWK-SKKYRF---SIYSFPWVNGRESSGIVVRRGEK 120
+P P +L PY++L++ +N +D+K Y+ +++ P + G + +G V+ G +
Sbjct: 35 IPNPAELGPYDVLVEVVATSINPLDYKLMNTYQMIAKALFKLPNIPGYDFAGRVLAVGSE 94
Query: 121 VDEEKFPLGGEVFIASTTYRDLRTS-TFQEYTVFDSRLVWRVPERIGLDFASGIGVSLVT 179
V E F V+ + R R + + V + VW +P+ + + +G G++ +T
Sbjct: 95 VKE--FSATQRVWGCQSFPRAGRQGGSCATHIVTGDKDVWHLPDGVSFNEGAGFGIAGLT 152
Query: 180 AGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQYLLS 239
A L R +KV+P K +VI G S GVG F V LAK+L ++ TI+S ++ S
Sbjct: 153 AWEVLV--RQMKVKPGTK--LVIEGASGGVGTFAVALAKALE-CEVTTISSTENLDLCKS 207
Query: 240 LGATHIIHREEKTEDIVNEIKKICP 264
LGATH + + K +++V + + P
Sbjct: 208 LGATHTL--DYKKDNLVERLADLGP 230
>SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 346
Score = 72.0 bits (175), Expect = 1e-12
Identities = 59/228 (25%), Positives = 100/228 (42%), Gaps = 21/228 (9%)
Query: 67 VPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSI-YSFPWVNGRESSGIVVRRGEKVDEEK 125
VPQKL P E+L+K K LN+ D K + + P V G + +GI+ + GE D E
Sbjct: 24 VPQKLNPGEVLVKLKAASLNYRDLIITKGLYPLPLQLPVVPGSDGAGIIEKVGE--DVEG 81
Query: 126 FPLGGEV---------------FIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFA 170
F G V F + R FQ+Y V + + P+ + +
Sbjct: 82 FEKGDSVVCNFFTNYLDGTPTDFATHSALGGTRDGCFQKYAVLPAHALVHAPKNLSFEEI 141
Query: 171 SGIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITS 230
+ + + VTA L + +V+P ++ G+ GV F +Q A + G +T +S
Sbjct: 142 ATLPCAAVTAWNGLFGSKEHQVKPGNNVLVL---GTGGVSTFALQFALAAGANVTVTSSS 198
Query: 231 KKHEQYLLSLGATHIIHREEKTEDIVNEIKKICPNGVSHGVDLISKKT 278
+ ++ LGATH I+ ++ + +K G H +++ +KT
Sbjct: 199 DEKLEFAKKLGATHTINYKKTPQWASPALKMTNGVGYHHVIEVGGEKT 246
>Hs18379349 [CR] KOG1197 Predicted quinone oxidoreductase
Length = 393
Score = 68.6 bits (166), Expect = 2e-11
Identities = 69/254 (27%), Positives = 119/254 (46%), Gaps = 19/254 (7%)
Query: 44 PQTQKGLVVSSFT--EDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFS-IY 100
P + LV++ F + +KL + P P ++ ++ + GLN D +++ + +
Sbjct: 45 PPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLP 104
Query: 101 SFPWVNGRESSGIVVRRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWR 160
P G E +G+V+ GE V + K G V + + R+ +QE S +
Sbjct: 105 PLPVTPGMEGAGVVIAVGEGVSDRK--AGDRVMVLN------RSGMWQEEVTVPSVQTFL 156
Query: 161 VPERIGLDFASGIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSL 220
+PE + + A+ + V+ +TA L N+ QP S+++ + GVG+ VQL +++
Sbjct: 157 IPEAMTFEEAAALLVNYITAYMVLFDFGNL--QPGH--SVLVHMAAGGVGMAAVQLCRTV 212
Query: 221 -GFTKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNEIKKICPNGVSHGVDLISKKTA 279
T T ++ KHE L G TH I + T D V+EIKKI P GV +D +
Sbjct: 213 ENVTVFGTASASKHEA-LKENGVTHPI--DYHTTDYVDEIKKISPKGVDIVMDPLGGSDT 269
Query: 280 ETLSSILSAESKLV 293
++L K+V
Sbjct: 270 AKGYNLLKPMGKVV 283
>YMR303c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 64.7 bits (156), Expect = 2e-10
Identities = 74/261 (28%), Positives = 112/261 (42%), Gaps = 36/261 (13%)
Query: 43 VPQTQKGLVVSSFTEDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSI-YS 101
+P+TQK ++ L+ D+PVP K KP E+LI KY G+ H D + + +
Sbjct: 3 IPETQKAIIFYESNGKLEH-KDIPVP-KPKPNELLINVKYSGVCHTDLHAWHGDWPLPTK 60
Query: 102 FPWVNGRESSGIVVRRGEKVDEEKF-------------------PLGGEVFIASTTYRDL 142
P V G E +G+VV GE V K LG E ++ + DL
Sbjct: 61 LPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNE---SNCPHADL 117
Query: 143 ----RTSTFQEYTVFDSRLVWRVPERIGLDFASGIGVSLVTAGAALASKRNVKVQPEEKK 198
+FQEY D+ +P+ L + I + +T AL S N++
Sbjct: 118 SGYTHDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGITVYKALKS-ANLRA----GH 172
Query: 199 SIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNE 258
I G + G+G VQ AK++G+ + E+ SLG I K +DIV+
Sbjct: 173 WAAISGAAGGLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEVFID-FTKEKDIVSA 231
Query: 259 IKKICPNGVSHGVDLISKKTA 279
+ K NG +HG+ +S A
Sbjct: 232 VVK-ATNGGAHGIINVSVSEA 251
>CE16009 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 328
Score = 63.9 bits (154), Expect = 4e-10
Identities = 71/298 (23%), Positives = 132/298 (43%), Gaps = 33/298 (11%)
Query: 63 TDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFS-IYSFPWVNGRESSGIVVRRGEKV 121
+D+P +L+ ++L++N G+N VD + ++ + + P+V G++ +G V GE V
Sbjct: 29 SDMP---RLEKNQVLVRNYAAGVNPVDTYIRAGQYGKLPNLPYVPGKDGAGFVELVGESV 85
Query: 122 DEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFASGIGVSLVTAG 181
K +G V+ S + EY + + +PE + + + +GV +TA
Sbjct: 86 KNVK--VGDRVWYGS------EADSTAEYVAVNRP--FELPEGVSFEEGASLGVPYLTAY 135
Query: 182 AALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQYLLSLG 241
AL K I++ G S GVG ++QLA + T S +++ SLG
Sbjct: 136 RALFHLAGAKTGDV----ILVHGASGGVGSALMQLAAWRNIEAVGTAGSADGIRFVKSLG 191
Query: 242 ATHIIHREEKTEDIVNEIKKICPNGVSHGVDLISKKTAETLSSILSAESKLVCAAGCPNK 301
A ++ + +K V+++K P G +H ++ + T +L+ + V G +
Sbjct: 192 ARNVYNHSDK--QYVSKMKNDYPGGFNHIFEMAAHTNLNTDLGLLAPRGR-VAVIGNRAE 248
Query: 302 AQVNDPTIKVE-------AINLKLFHEDLDYGQEFVRYTTELFEKNRLKPLSNLKLFK 352
+N + V A+ + E LD+G V + E +PL N KL++
Sbjct: 249 TTINARQLMVTEGAVYGVALGMSSEAELLDFGINIVSFLKE----TEFRPLIN-KLYR 301
>At5g61510 [CR] KOG1197 Predicted quinone oxidoreductase
Length = 324
Score = 62.8 bits (151), Expect = 8e-10
Identities = 66/239 (27%), Positives = 105/239 (43%), Gaps = 17/239 (7%)
Query: 72 KPYEILIKNKYIGLNHVDWKSKKYRFSIYSFPWVNGRESSGIVVRRGEKVDEEKFPLGGE 131
K EI +KNK IGLN +D +K + S P+ G E+ G VV G L G
Sbjct: 27 KEGEIRVKNKAIGLNFIDVYFRKGVYKPASMPFTPGMEAVGEVVAVGS-------GLTGR 79
Query: 132 VFIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFASGIGVSLVTAGAALASKRNVK 191
+ Y + E + + V VP I A+ I + +TA L +R K
Sbjct: 80 MIGDLVAYAGNPMGAYAEEQILPADKVVPVPSSIDPIVAASIMLKGMTAQFLL--RRCFK 137
Query: 192 VQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQYLLSLGATHIIHREEK 251
V+P +I++ + GVG + Q A +LG T I T+++ + G H+I K
Sbjct: 138 VEPGH--TILVHAAAGGVGSLLCQWANALGATVIGTVSTNEKAAQAKEDGCHHVI--MYK 193
Query: 252 TEDIVNEIKKICP-NGVSHGVDLISKKTAETLSSILSAESKLVC---AAGCPNKAQVND 306
ED V+ + I GV+ D + K T + + L + +V ++G P+ ++D
Sbjct: 194 NEDFVSRVNDITSGKGVNVVYDSVGKDTFKGSLACLKSRGYMVSFGQSSGSPDPIPLSD 252
>YOL086c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 61.6 bits (148), Expect = 2e-09
Identities = 72/261 (27%), Positives = 111/261 (41%), Gaps = 36/261 (13%)
Query: 43 VPQTQKGLVVSSFTEDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSI-YS 101
+P+TQKG++ L+ D+PVP K K E+LI KY G+ H D + + +
Sbjct: 3 IPETQKGVIFYESHGKLEY-KDIPVP-KPKANELLINVKYSGVCHTDLHAWHGDWPLPVK 60
Query: 102 FPWVNGRESSGIVVRRGEKVDEEKF-------------------PLGGEVFIASTTYRDL 142
P V G E +G+VV GE V K LG E ++ + DL
Sbjct: 61 LPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNE---SNCPHADL 117
Query: 143 RTST----FQEYTVFDSRLVWRVPERIGLDFASGIGVSLVTAGAALASKRNVKVQPEEKK 198
T FQ+Y D+ +P+ L + I + +T AL S +
Sbjct: 118 SGYTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSANLMAGH----- 172
Query: 199 SIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNE 258
+ I G + G+G VQ AK++G+ + + E+ S+G I K +DIV
Sbjct: 173 WVAISGAAGGLGSLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFID-FTKEKDIVGA 231
Query: 259 IKKICPNGVSHGVDLISKKTA 279
+ K +G +HGV +S A
Sbjct: 232 VLK-ATDGGAHGVINVSVSEA 251
>SPCC1442.16c [CR] KOG1197 Predicted quinone oxidoreductase
Length = 329
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/233 (26%), Positives = 108/233 (46%), Gaps = 26/233 (11%)
Query: 59 LKLLT-DLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIYS--FPWVNGRESSGIVV 115
L+++T ++P P P ++IKN Y GLN++D R +Y+ P++ G+E++G+V
Sbjct: 17 LQVITKEIPKPA---PNGLVIKNAYAGLNYID---TYLRTGLYTAPLPYIPGKEAAGVVA 70
Query: 116 RRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFASGIGV 175
G+KV E F +G V + + +YT + LV +V E+I L AS +
Sbjct: 71 AVGDKV-EADFKVGDRVVYLTP------FGAYAQYTNVPTTLVSKVSEKIPLKIASAALL 123
Query: 176 SLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQ 235
+TA + VK ++V+ + GVG+ + Q+ ++ I T ++ +
Sbjct: 124 QGLTAYTLIEEAYPVKT----GDTVVVHAAAGGVGLLLCQMLRARNVHVIATASTAAKRR 179
Query: 236 YLLSLGATHIIHREEKTEDIVNEIKKICPNGVSHGVDLISKKTAETLSSILSA 288
+ GA E+ T+ + + GV D + +TLSS L A
Sbjct: 180 IAIKNGAEIACSYEDLTKVVADYTN---GKGVDAAYDSVG---IDTLSSSLDA 226
>YBR145w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 61.2 bits (147), Expect = 2e-09
Identities = 84/292 (28%), Positives = 123/292 (41%), Gaps = 41/292 (14%)
Query: 41 EYVPQTQKGLVVSSFTEDLKL-LTDLPVPQKLKPYEILIKNKYIGLNHVD---WKSKKYR 96
+ +P+ QK +V + D KL D+ VP+ KP EIL+ KY G+ H D W +
Sbjct: 4 QVIPEKQKAIVF--YETDGKLEYKDVTVPEP-KPNEILVHVKYSGVCHSDLHAWHGD-WP 59
Query: 97 FSIYSFPWVNGRESSGIVVRRGEKVDEEKF-PLGGEVFIAST---------------TYR 140
F + FP + G E +G+VV+ G V K G ++ T Y
Sbjct: 60 FQL-KFPLIGGHEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCMSCEYCEVGNESQCPYL 118
Query: 141 D----LRTSTFQEYTVFDSRLVWRVPERIGLDFASGIGVSLVTAGAALASKRNVKVQPEE 196
D TFQEY D+ +P + L + I + +T AL + V P +
Sbjct: 119 DGTGFTHDGTFQEYATADAVQAAHIPPNVNLAEVAPILCAGITVYKAL---KRANVIPGQ 175
Query: 197 KKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQYLLSL--GATHIIHREEKTED 254
+ I G G+G +Q A ++G+ ++I I ++ L G I EEK D
Sbjct: 176 --WVTISGACGGLGSLAIQYALAMGY-RVIGIDGGNAKRKLFEQLGGEIFIDFTEEK--D 230
Query: 255 IVNEIKKICPNGVSHGVDLIS-KKTAETLSSILSAESKLVCAAGCPNKAQVN 305
IV I K NG SHGV +S + A S+ + V G P A N
Sbjct: 231 IVGAIIK-ATNGGSHGVINVSVSEAAIEASTRYCRPNGTVVLVGMPAHAYCN 281
>At4g13010 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 329
Score = 61.2 bits (147), Expect = 2e-09
Identities = 53/186 (28%), Positives = 90/186 (47%), Gaps = 11/186 (5%)
Query: 65 LPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIY---SFPWVNGRESSGIVVRRGEKV 121
+PVP K E+ +K + LN VDWK +K + FP + + +G VV G V
Sbjct: 26 VPVPTP-KSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGV 84
Query: 122 DEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFASGIGVSLVTAG 181
K G+ +A ++ L E+ V +L + P+ +G A+ + V+ +TA
Sbjct: 85 KNFK---AGDKVVAVLSH--LGGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTAL 139
Query: 182 AALASKRNVKVQPEEKKS-IVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHEQYLLSL 240
AL + +K+ KK+ I++ S GVG + VQLAK L + ++ +++ SL
Sbjct: 140 QALTNPAGLKLDGTGKKANILVTAASGGVGHYAVQLAK-LANAHVTATCGARNIEFVKSL 198
Query: 241 GATHII 246
GA ++
Sbjct: 199 GADEVL 204
>At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 348
Score = 59.3 bits (142), Expect = 9e-09
Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 14/172 (8%)
Query: 103 PWVNGRESSGIVVRRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVP 162
P++ G + SGIV G V KF +G V ++ DL +F ++ V D ++ VP
Sbjct: 69 PFIPGSDYSGIVDAIGPAVT--KFRVGDRV----CSFADL--GSFAQFIVADQSRLFLVP 120
Query: 163 ERIGLDFASGIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGF 222
ER + A+ + V+ T+ AL + + + +++ G + GVG+ VQ+ K G
Sbjct: 121 ERCDMVAAAALPVAFGTSHVALVHRARLT----SGQVLLVLGAAGGVGLAAVQIGKVCGA 176
Query: 223 TKIITITSKKHEQYLLSLGATHIIHREEKTEDIVNEIKKICPNGVSHGVDLI 274
I + Q L S+G H++ + TE++++ +K+ GVD++
Sbjct: 177 IVIAVARGTEKIQLLKSMGVDHVV--DLGTENVISSVKEFIKTRKLKGVDVL 226
>At3g15090 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 366
Score = 58.5 bits (140), Expect = 2e-08
Identities = 58/207 (28%), Positives = 97/207 (46%), Gaps = 15/207 (7%)
Query: 57 EDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKK-YRFSIYS--FPWVNGRESSGI 113
E +L ++PVP L P E+L+K K + +N +D + + Y S++ P + GR+ SG
Sbjct: 44 EVFELRENVPVPN-LNPNEVLVKAKAVSVNPLDCRIRAGYGRSVFQPHLPIIVGRDVSGE 102
Query: 114 VVRRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVPERIGLDFASGI 173
V G V K +G EVF A + T+ +Y + + P I AS I
Sbjct: 103 VAAIGTSVKSLK--VGQEVFGA--LHPTALRGTYTDYGILSEDELTEKPSSISHVEASAI 158
Query: 174 GVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKH 233
+ +TA AL S + E + ++++GG VG +QLA + G + +
Sbjct: 159 PFAALTAWRALKSNARIT----EGQRLLVFGGGGAVGFSAIQLAVASGCHVTASCVGQTK 214
Query: 234 EQYLLSLGATHIIHREEKTEDIVNEIK 260
++ +L+ GA + + TEDI +K
Sbjct: 215 DR-ILAAGAEQAV--DYTTEDIELAVK 238
>CE19192 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 346
Score = 54.7 bits (130), Expect = 2e-07
Identities = 67/268 (25%), Positives = 120/268 (44%), Gaps = 32/268 (11%)
Query: 48 KGLVVSSFTEDLKLLT--DLPVPQKLKPYEILIKNKYIGLNHVDWKSKKYRFSIYS-FPW 104
+ L+ F + LK+L + VP + E L++ +N +D + +++ + P
Sbjct: 8 QALIYRKFGDPLKVLQLETVEVPAEPGSGECLVEWLASPINPLDINRIQGNYAVRAELPV 67
Query: 105 VNGRESSGIVVRRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRLVWRVPER 164
+ G E G VV+ G +F G V I S T + E+ V D + ++ R
Sbjct: 68 IGGSEGVGRVVKAGSG---SRFKSGDHVTIFSAN-----TPIWTEFGVVDDDELVKLDNR 119
Query: 165 IGLDFASGIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSLGFTK 224
I LD A+ + ++ TA L K+ V +Q + I+ ++GVG V+++ K+LG+
Sbjct: 120 IPLDLAATLMINPPTAWIML--KKYVNLQKGDY--IIQNSANSGVGRSVIEMCKALGYKS 175
Query: 225 IITITSKKHEQYLLS----LGATHIIHREE------KTEDIVNEIKKICPNGVSHGVDLI 274
I + ++++ + L + +GA H+ EE + +N K+ NGV
Sbjct: 176 INIVRNRQNIEALKTDLWRIGADHVFTEEEFKGTSRQFLKSINVRPKLALNGV------- 228
Query: 275 SKKTAETLSSILSAESKLVCAAGCPNKA 302
K+A +SS+L V G KA
Sbjct: 229 GGKSALQISSVLERGGTCVTYGGMSKKA 256
>YDL168w [Q] KOG0022 Alcohol dehydrogenase class III
Length = 386
Score = 53.9 bits (128), Expect = 4e-07
Identities = 62/246 (25%), Positives = 97/246 (39%), Gaps = 50/246 (20%)
Query: 72 KPYEILIKNKYIGLNHVDWKSKKYRFSIYSFPWVNGRESSGIVVRRGEKV---------- 121
K +E+ IK +Y + H D + FP V G E +GIV G+ V
Sbjct: 35 KAHEVRIKIEYTAVCHTDAYTLSGSDPEGLFPCVLGHEGAGIVESVGDDVITVKPGDHVI 94
Query: 122 -------DEEKFPLGGEVFIASTT------------------------YRDLRTSTFQEY 150
+ KF G+ + Y + STF EY
Sbjct: 95 ALYTAECGKCKFCTSGKTNLCGAVRATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEY 154
Query: 151 TVFDSRLVWRVPERIGLDFASGIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVG 210
TV V + + LD A +G + T A NV ++ ++ ++G T VG
Sbjct: 155 TVVADVSVVAIDPKAPLDAACLLGCGVTTGFGAALKTANV----QKGDTVAVFGCGT-VG 209
Query: 211 IFVVQLAKSLGFTKIITI-TSKKHEQYLLSLGATHIIHREE---KTEDIVNEIKKICPNG 266
+ V+Q AK G +KII I + K +QY GAT ++ +E K + IV ++ ++ G
Sbjct: 210 LSVIQGAKLRGASKIIAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGG 269
Query: 267 VSHGVD 272
+ D
Sbjct: 270 LDFTFD 275
>Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 374
Score = 52.4 bits (124), Expect = 1e-06
Identities = 43/142 (30%), Positives = 71/142 (49%), Gaps = 22/142 (15%)
Query: 142 LRTSTFQEYTVFDSRLVWRV-----PER---IGLDFASGIGVSLVTAGAALASKRNVKVQ 193
+ TSTF EYTV D V ++ PE+ IG F++G G ++ T KV+
Sbjct: 141 MNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG----------KVK 190
Query: 194 PEEKKSIVIWGGSTGVGIFVVQLAKSLGFTKIITITSKKHE-QYLLSLGATHIIHREEKT 252
P S + G GVG+ V+ KS G ++II I K + + +++GAT I ++ T
Sbjct: 191 P---GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 247
Query: 253 EDIVNEIKKICPNGVSHGVDLI 274
+ I + ++ N V + ++I
Sbjct: 248 KPISEVLSEMTGNNVGYTFEVI 269
>YBL069w [CR] KOG1198 Zinc-binding oxidoreductase
Length = 429
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/210 (26%), Positives = 102/210 (47%), Gaps = 26/210 (12%)
Query: 55 FTEDLKLLTDLPVPQKLKPYEILIKNKYIGLNHVDWKSKK-YRFSIYSFPWVNGRESSGI 113
F+ + K+ T P+P+ +I+++ +GLN VD K + Y SIY + GRE SG+
Sbjct: 64 FSYEKKIKT--PIPKN----KIVVRVSNVGLNPVDMKIRNGYTSSIYGEIGL-GREYSGV 116
Query: 114 VVRRGEKVDEEKFPLGGEVFIASTTYRDLRTSTFQEYTVFDSRL--VWRVPERIGLDFAS 171
+ GE ++ + +G EV+ + L Q + D ++ + PE + + A+
Sbjct: 117 ITEVGENLNYA-WHVGDEVY-GIYYHPHLAVGCLQSSILVDPKVDPILLRPESVSAEEAA 174
Query: 172 GIGVSLVTAGAALASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKS--LGFTKIITIT 229
G L T G + +K + ++ +++I GG++ VG+FV+QL K K++ +T
Sbjct: 175 GSLFCLAT-GYNILNKLSKNKYLKQDSNVLINGGTSSVGMFVIQLLKRHYKLQKKLVIVT 233
Query: 230 SKKHEQYLLSLGATHIIHREEKTEDIVNEI 259
S Q L +EK D+ +E+
Sbjct: 234 SANGPQVL-----------QEKFPDLADEM 252
>YER101c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 430
Score = 50.1 bits (118), Expect = 6e-06
Identities = 56/228 (24%), Positives = 107/228 (46%), Gaps = 24/228 (10%)
Query: 9 EPFNVLEETIPGVHQEVKRFKNAKTEELYTSLEYVPQTQKGLVVSSFTEDLKLLTDLPVP 68
+P V E T+ V + ++ ++ + L V ++ G + S+ +KL P+
Sbjct: 26 KPIPVDEPTLTRVARPLRHVRHIPVKSL------VFHSKHGPITFSYENKIKL----PIS 75
Query: 69 QKLKPYEILIKNKYIGLNHVDWKSKK-YRFSIYSFPWVNGRESSGIVVRRGEKVDEEKFP 127
+ +++++ Y+GLN VD K + Y IY + GRE SG++ G+ + ++
Sbjct: 76 KN----KLVVQVNYVGLNPVDMKIRNGYTKPIYGEAGI-GREYSGVITHVGDNLTN-RWN 129
Query: 128 LGGEVFIASTTYRDLRTSTFQEYTVFDSR---LVWRVPERIGLDFASGIGVSLVTAGAAL 184
+G +V+ + L Q + D R ++ R + + A+G L TA L
Sbjct: 130 VGDDVY-GIYYHPKLAIGALQSSLLIDPRVDPILMRPKNTLSPEKAAGSLFCLGTALNLL 188
Query: 185 ASKRNVKVQPEEKKSIVIWGGSTGVGIFVVQLAKSL--GFTKIITITS 230
A + K Q + +++I GG++ VG+F +QL K K++ +TS
Sbjct: 189 AQLKE-KDQLNTESNVLINGGTSSVGMFAIQLLKRYYKVSKKLVVVTS 235
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,036,800
Number of Sequences: 60738
Number of extensions: 942948
Number of successful extensions: 2802
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2771
Number of HSP's gapped (non-prelim): 26
length of query: 382
length of database: 30,389,216
effective HSP length: 108
effective length of query: 274
effective length of database: 23,829,512
effective search space: 6529286288
effective search space used: 6529286288
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)