ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0249 good DO KOG1546 Cell cycle control, cell division, chromosome partitioning Metacaspase involved in regulation of apoptosis
r_klactVI0249 good DO KOG1546 Posttranslational modification, protein turnover, chaperones Metacaspase involved in regulation of apoptosis
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0249 81665 83032 456
(456 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR197w [DO] KOG1546 Metacaspase involved in regulation of apopt... 473 e-133
SPCC1840.04 [DO] KOG1546 Metacaspase involved in regulation of a... 355 6e-98
At1g02170 [DO] KOG1546 Metacaspase involved in regulation of apo... 151 2e-36
At5g64240 [DO] KOG1546 Metacaspase involved in regulation of apo... 141 2e-33
At4g25110 [DO] KOG1546 Metacaspase involved in regulation of apo... 139 7e-33
At1g79340 [DO] KOG1546 Metacaspase involved in regulation of apo... 101 3e-21
At5g04200 [DO] KOG1546 Metacaspase involved in regulation of apo... 97 4e-20
At1g79330 [DO] KOG1546 Metacaspase involved in regulation of apo... 95 2e-19
At1g79320 [DO] KOG1546 Metacaspase involved in regulation of apo... 95 2e-19
At1g79310 [DO] KOG1546 Metacaspase involved in regulation of apo... 95 2e-19
At1g16420 [DO] KOG1546 Metacaspase involved in regulation of apo... 91 3e-18
>YOR197w [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 453
Score = 473 bits (1217), Expect = e-133
Identities = 236/364 (64%), Positives = 276/364 (74%), Gaps = 4/364 (1%)
Query: 96 YARPAAPPPG--QQNYRNDIQQNHASGTVNGPSGYQQPQAMYKPPSQVQHTGPNNQVAYQ 153
Y RP PPP Q+ + + + + VN + Y PQ M PP Q Q +Q YQ
Sbjct: 91 YNRPVYPPPQFQQEQAKAQLSNGYNNPNVNASNMYGPPQNMSLPPPQTQTIQGTDQ-PYQ 149
Query: 154 YSQCTGRRKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPV 213
YSQCTGRRKAL+IGINY GS N+LRGCIND+HN+FNFLT YGY ++DIV+L DD D V
Sbjct: 150 YSQCTGRRKALIIGINYIGSKNQLRGCINDAHNIFNFLTNGYGYSSDDIVILTDDQNDLV 209
Query: 214 RVPTKANMLRAMQWLVKDARPNDALFFHYSGHXXXXXXXXXXXXXXXXXVIYPVDFQMAG 273
RVPT+ANM+RAMQWLVKDA+PND+LF HYSGH VIYPVDF+ G
Sbjct: 210 RVPTRANMIRAMQWLVKDAQPNDSLFLHYSGHGGQTEDLDGDEEDGMDDVIYPVDFETQG 269
Query: 274 HIVDDDMHAIMVSPLQPGVRLTALFDSCHSGTVLDLPYTYSTKGVIKEPNMWKDVGSSGL 333
I+DD+MH IMV PLQ GVRLTALFDSCHSGTVLDLPYTYSTKG+IKEPN+WKDVG GL
Sbjct: 270 PIIDDEMHDIMVKPLQQGVRLTALFDSCHSGTVLDLPYTYSTKGIIKEPNIWKDVGQDGL 329
Query: 334 QAAMAYATGNTTSLVSSLGNVFTTITKS-NNNVDRERVKQIKFSPADVIMFSGSKDNQTS 392
QAA++YATGN +L+ SLG++F T+ NNVDRERV+QIKFS ADV+M SGSKDNQTS
Sbjct: 330 QAAISYATGNRAALIGSLGSIFKTVKGGMGNNVDRERVRQIKFSAADVVMLSGSKDNQTS 389
Query: 393 ADATENGQNTGAMSWAFLTVLSKQPQQSYLSLLQNMRAELSSKYTQKPQLSCSHEIDTNL 452
ADA E+GQNTGAMS AF+ V++ QPQQSYLSLLQNMR EL+ KY+QKPQLS SH ID NL
Sbjct: 390 ADAVEDGQNTGAMSHAFIKVMTLQPQQSYLSLLQNMRKELAGKYSQKPQLSSSHPIDVNL 449
Query: 453 QFLL 456
QF++
Sbjct: 450 QFIM 453
>SPCC1840.04 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 425
Score = 355 bits (912), Expect = 6e-98
Identities = 184/361 (50%), Positives = 232/361 (63%), Gaps = 13/361 (3%)
Query: 96 YARPAAPPPGQQNYRNDIQQNHASGTVNGPSGYQQPQAMYKPPSQVQHTGPNNQVAYQYS 155
YA P+ PPP N + + P+ Y PQ G N YQYS
Sbjct: 78 YAPPSGPPP-----------NTGANSYGNPN-YSGPQLPNTQTQSYNLAGGGN-FQYQYS 124
Query: 156 QCTGRRKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRV 215
C G+RKALLIGINY + NEL+GCIND +M L QRYGYK ED+V++ D ++ +
Sbjct: 125 TCQGKRKALLIGINYLNTQNELQGCINDVMSMSQLLIQRYGYKQEDMVIMTDTASNQRAI 184
Query: 216 PTKANMLRAMQWLVKDARPNDALFFHYSGHXXXXXXXXXXXXXXXXXVIYPVDFQMAGHI 275
PT+ NML AM+WLV DA+PNDALFFHYSGH IYP+D Q AG I
Sbjct: 185 PTRQNMLDAMRWLVSDAQPNDALFFHYSGHGGQTKDLDGDEVDGYDETIYPLDHQYAGQI 244
Query: 276 VDDDMHAIMVSPLQPGVRLTALFDSCHSGTVLDLPYTYSTKGVIKEPNMWKDVGSSGLQA 335
+DD+MH IMV PL G RLTALFDSCHSG LDLP+TYSTKGV+KEPNM K+ G L A
Sbjct: 245 IDDEMHEIMVKPLPAGCRLTALFDSCHSGGALDLPFTYSTKGVLKEPNMLKESGMDVLHA 304
Query: 336 AMAYATGNTTSLVSSLGNVFTTITKSNNNVDRERVKQIKFSPADVIMFSGSKDNQTSADA 395
++YA+G+ ++++ N+FT+ T NN + +Q+KFSPADVI SG KDNQTSAD
Sbjct: 305 GLSYASGDIMGAINNVKNIFTSATNGFNNNALQYSRQVKFSPADVISLSGCKDNQTSADT 364
Query: 396 TENGQNTGAMSWAFLTVLSKQPQQSYLSLLQNMRAELSSKYTQKPQLSCSHEIDTNLQFL 455
+ NG TGA+S+AF V+++ PQ SYL LL+ +R LS+KY+Q PQLSCSH +D NL +
Sbjct: 365 SVNGFATGALSYAFREVVTQNPQLSYLQLLRGIRQVLSNKYSQLPQLSCSHPLDMNLAMV 424
Query: 456 L 456
L
Sbjct: 425 L 425
>At1g02170 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 379
Score = 151 bits (381), Expect = 2e-36
Identities = 101/319 (31%), Positives = 151/319 (46%), Gaps = 62/319 (19%)
Query: 130 QPQAMYKPPSQVQHTGPNNQVAYQYSQCTGRRKALLIGINYFGSANELRGCINDSHNMFN 189
QP + PP Q+ P Q+ + + GR++A++ GI+Y S +EL+GCIND+ M +
Sbjct: 55 QPSSAPSPPPQIH--APPGQLPHPH----GRKRAVICGISYRFSRHELKGCINDAKCMRH 108
Query: 190 FLTQRYGYKAEDIVMLNDDTTDPVRVPTKANMLRAMQWLVKDARPNDALFFHYSGHXXXX 249
L ++ + + I+ML ++ TDP R+PTK NM A+ WLV+ D+L FHYSGH
Sbjct: 109 LLINKFKFSPDSILMLTEEETDPYRIPTKQNMRMALYWLVQGCTAGDSLVFHYSGHGSRQ 168
Query: 250 XXXXXXXXXXXXXVIYPVDFQMAGHIVDDDMHAIMVSPLQPGVRLTALFDSCHSGTVLDL 309
+ P+DF+ G IVDD+++A +V PL GV+L ++ D+CHSGTVLDL
Sbjct: 169 RNYNGDEVDGYDETLCPLDFETQGMIVDDEINATIVRPLPHGVKLHSIIDACHSGTVLDL 228
Query: 310 PYTYSTKGVIKEPNMWKD-VGSSGLQAAMAYATGNTTSLVSSLGNVFTTITKSNNNVDRE 368
P+ +W+D SGL A
Sbjct: 229 PFLCRMNRA--GQYVWEDHRPRSGLWKGTA------------------------------ 256
Query: 369 RVKQIKFSPADVIMFSGSKDNQTSAD--------------ATENGQNTGAMSWAFLTVLS 414
+ I SG D+QTSAD A +TGAM++ F+ +
Sbjct: 257 --------GGEAISISGCDDDQTSADTSLVPPLMIKTHTQALSKITSTGAMTFCFIQAIE 308
Query: 415 KQPQ-QSYLSLLQNMRAEL 432
+ Q +Y SLL +MR +
Sbjct: 309 RSAQGTTYGSLLNSMRTTI 327
>At5g64240 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 362
Score = 141 bits (355), Expect = 2e-33
Identities = 69/183 (37%), Positives = 109/183 (58%), Gaps = 9/183 (4%)
Query: 129 QQPQAMYKPPSQVQHTGPNNQVAYQYSQCTGRRKALLIGINYFGSANELRGCINDSHNMF 188
QQ Q M +PP ++ P+ G+++A+L G+NY G + L+GCI+D+ +M
Sbjct: 67 QQQQMMAQPPPRLLEPLPSP---------FGKKRAVLCGVNYKGKSYSLKGCISDAKSMR 117
Query: 189 NFLTQRYGYKAEDIVMLNDDTTDPVRVPTKANMLRAMQWLVKDARPNDALFFHYSGHXXX 248
+ L Q+ G+ + I+ML +D P R+PTK N+ +AM+WLV+ R D+L FH+SGH
Sbjct: 118 SLLVQQMGFPIDSILMLTEDEASPQRIPTKRNIRKAMRWLVEGNRARDSLVFHFSGHGSQ 177
Query: 249 XXXXXXXXXXXXXXVIYPVDFQMAGHIVDDDMHAIMVSPLQPGVRLTALFDSCHSGTVLD 308
+ P+D + G I+DD+++ I+V PL G +L A+ D+C+SGTVLD
Sbjct: 178 QNDYNGDEIDGQDEALCPLDHETEGKIIDDEINRILVRPLVHGAKLHAVIDACNSGTVLD 237
Query: 309 LPY 311
LP+
Sbjct: 238 LPF 240
>At4g25110 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 393
Score = 139 bits (351), Expect = 7e-33
Identities = 71/182 (39%), Positives = 109/182 (59%), Gaps = 10/182 (5%)
Query: 159 GRRKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTK 218
G+++A+++G++Y + +EL+GCIND++ M L +R+ + I+ML ++ DP+R PTK
Sbjct: 114 GQKRAVIVGVSYKNTKDELKGCINDANCMKFMLMKRFQFPESCILMLTEEEADPMRWPTK 173
Query: 219 ANMLRAMQWLVKDARPNDALFFHYSGHXXXXXXXXXXXXXXXXXVIYPVDFQMAGHIVDD 278
N+ AM WLV +P D+L FH+SGH + PVD + +G IVDD
Sbjct: 174 NNITMAMHWLVLSCKPGDSLVFHFSGHGNNQMDDNGDEVDGFDETLLPVDHRTSGVIVDD 233
Query: 279 DMHAIMVSPLQPGVRLTALFDSCHSGTVLDLPY--------TYSTKGVIKEPNMWKDVGS 330
+++A +V PL GV+L A+ D+CHSGTV+DLPY Y + + MWK G+
Sbjct: 234 EINATIVRPLPYGVKLHAIVDACHSGTVMDLPYLCRMDRLGNYEWEDHRPKTGMWK--GT 291
Query: 331 SG 332
SG
Sbjct: 292 SG 293
>At1g79340 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 418
Score = 101 bits (251), Expect = 3e-21
Identities = 60/149 (40%), Positives = 80/149 (53%), Gaps = 6/149 (4%)
Query: 161 RKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTKAN 220
+KA+LIGINY G+ ELRGC+ND M+ L +RYG+ E+I +L DT + PT N
Sbjct: 3 KKAVLIGINYPGTKAELRGCVNDVRRMYKCLVERYGFSEENITVL-IDTDESSTQPTGKN 61
Query: 221 MLRAMQWLVKDARPNDALFFHYSGHXXXX-XXXXXXXXXXXXXVIYPVDFQMAGHIVDDD 279
+ RA+ LV+ A D L HYSGH I P D + I DDD
Sbjct: 62 IRRALADLVESADSGDVLVVHYSGHGTRLPAETGEDDDTGFDECIVPCDMNL---ITDDD 118
Query: 280 MHAIMVSPLQPGVRLTALFDSCHSGTVLD 308
+V + PG R+T + DSCHSG ++D
Sbjct: 119 FRD-LVDKVPPGCRMTIISDSCHSGGLID 146
>At5g04200 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 325
Score = 97.4 bits (241), Expect = 4e-20
Identities = 94/324 (29%), Positives = 139/324 (42%), Gaps = 53/324 (16%)
Query: 160 RRKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTKA 219
+R A+L+G NY + NEL GCIND M + R+G+K +DI +L D+ V+ PT A
Sbjct: 9 KRLAVLVGCNYPNTRNELHGCINDVLAMKETILSRFGFKQDDIEVLTDEPESKVK-PTGA 67
Query: 220 NMLRAMQWLVKDAR--PNDALFFHYSGHXXXXXXXXXXXXXXXXXVIYPVDFQMAGHIVD 277
N+ A++ +V A+ D LFFHYSGH I P DF + I D
Sbjct: 68 NIKAALRRMVDKAQAGSGDILFFHYSGHGTRIPSVKSAHPFKQDEAIVPCDFNL---ITD 124
Query: 278 DDMHAIMVSPLQPGVRLTALFDSCHSGTVLDL------PYTYSTKGVIKEPNMWKDVGSS 331
D +V+ L G T + DSCHSG ++D P + S+ K + S
Sbjct: 125 VDFRE-LVNQLPKGTSFTMISDSCHSGGLIDKEKEQIGPSSVSSNISPAIETTNKTITSR 183
Query: 332 GLQAA-----MAYATGNTTSLVSS--------------------LGNVFTTITKSNNNVD 366
L ++ TG TTS + + L ++ T+T +VD
Sbjct: 184 ALPFKAVLDHLSSLTGITTSDIGTHLLELFGRDAGLKFRLPAMDLMDLLETMTAREKHVD 243
Query: 367 RERVKQIKFSPADVIMFSGSKDNQTSAD-ATENGQNTGAMSWAFLTVLSKQPQQSYLSLL 425
I+ SG + ++TSAD NG+ GA S A VL++ L
Sbjct: 244 ------------SGILMSGCQADETSADVGVGNGKAYGAFSNAIQRVLNENEGAMKNKQL 291
Query: 426 QNMRAELSSK--YTQKPQLSCSHE 447
M ++ + + Q P L CS +
Sbjct: 292 VMMARDVLERLGFHQHPCLYCSDQ 315
>At1g79330 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 410
Score = 94.7 bits (234), Expect = 2e-19
Identities = 76/245 (31%), Positives = 110/245 (44%), Gaps = 14/245 (5%)
Query: 161 RKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTKAN 220
+KA+LIGINY G+ ELRGC+ND + L R+G+ +I L DT + PT N
Sbjct: 3 KKAVLIGINYPGTKAELRGCVNDVRRVHKSLVDRFGFSERNITEL-IDTDESSTKPTGKN 61
Query: 221 MLRAMQWLVKDARPNDALFFHYSGHXXXX-XXXXXXXXXXXXXVIYPVDFQMAGHIVDDD 279
+ RA+ LV+ A+P D L HYSGH I P D +++ DD
Sbjct: 62 IRRALLNLVESAKPGDVLVVHYSGHGTRLPAETGEDDDTGYDECIVPCDM----NLITDD 117
Query: 280 MHAIMVSPLQPGVRLTALFDSCHSGTVLDLPYTYSTKGVIKEPNMWKDVGSSGLQAAMAY 339
+V + +T + DSCHSG ++D + K+P + GSSGL +
Sbjct: 118 EFRDLVEKVPKEAHITIISDSCHSGGLIDEAKEQIGESTKKKPKK-ESGGSSGL-GIKGF 175
Query: 340 ATGNTTSLVSSLGNVFTTITKSNNNVDRERVKQIKFSP-ADVIMFSGSKDNQTSADATEN 398
+ S G I + D + K++K A V + + S QT D +
Sbjct: 176 VREAVEEALESKG---IAIPHHKDEKDENKTKELKLEDGAKVHVVNKSLPLQTLIDILK- 231
Query: 399 GQNTG 403
QNTG
Sbjct: 232 -QNTG 235
>At1g79320 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 368
Score = 94.7 bits (234), Expect = 2e-19
Identities = 58/149 (38%), Positives = 79/149 (52%), Gaps = 6/149 (4%)
Query: 161 RKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTKAN 220
+KALLIGINY G+ ELRGC+ND M L +RYG+ E+I ML D + ++ PT N
Sbjct: 3 KKALLIGINYVGTKAELRGCVNDVRRMRISLVERYGFSEENIKMLIDTDSSSIK-PTGKN 61
Query: 221 MLRAMQWLVKDARPNDALFFHYSGHXXXX-XXXXXXXXXXXXXVIYPVDFQMAGHIVDDD 279
+ +A+ LV+ A+ D LF HYSGH I P D + I DDD
Sbjct: 62 IRQALLDLVEPAKSGDVLFVHYSGHGTRLPAETGEDDDTGYDECIVPSDMNL---ITDDD 118
Query: 280 MHAIMVSPLQPGVRLTALFDSCHSGTVLD 308
+V + +T + DSCHSG ++D
Sbjct: 119 FRD-LVDMVPKDCPITIISDSCHSGGLID 146
>At1g79310 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 388
Score = 94.7 bits (234), Expect = 2e-19
Identities = 58/170 (34%), Positives = 82/170 (48%), Gaps = 19/170 (11%)
Query: 161 RKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTKAN 220
++ALLIGINY G+ EL+GC+ND H M L R+G+ EDI +L DT + PT N
Sbjct: 3 KRALLIGINYPGTTEELQGCVNDVHRMHKCLVDRFGFAEEDITVL-IDTDESYTQPTGKN 61
Query: 221 MLRAMQWLVKDARPNDALFFHYSGHXXXXXXXXXXXXXXXXXVIYPVDFQMAGHIVDDDM 280
+ +A+ L+K A+ D LF HYSGH V + DD
Sbjct: 62 IRQALSELIKPAKSGDVLFVHYSGHGTR------------------VPPETGEEDDTDDD 103
Query: 281 HAIMVSPLQPGVRLTALFDSCHSGTVLDLPYTYSTKGVIKEPNMWKDVGS 330
+V + G ++T + DSCHSG ++D + +PN V S
Sbjct: 104 FRDLVEQVPEGCQITIVSDSCHSGGLIDEAKEQIGESTTTKPNRESKVSS 153
>At1g16420 [DO] KOG1546 Metacaspase involved in regulation of apoptosis
Length = 381
Score = 91.3 bits (225), Expect = 3e-18
Identities = 55/149 (36%), Positives = 78/149 (51%), Gaps = 7/149 (4%)
Query: 161 RKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTKAN 220
+KALLIGINY G+A ELRGC+ND H M L + YG+ +DIV++ D ++ PT N
Sbjct: 3 KKALLIGINYPGTAVELRGCVNDVHRMQKCLIELYGFANKDIVIMIDTDKSCIQ-PTGKN 61
Query: 221 MLRAMQWLVKDARPNDALFFHYSGHXXXX--XXXXXXXXXXXXXVIYPVDFQMAGHIVDD 278
+ + L+ + D L FHYSGH I P D +++ D
Sbjct: 62 ICDELDNLIASGQSGDFLVFHYSGHGTRIPPGIEDSEDPTGFDECITPCDM----NLIKD 117
Query: 279 DMHAIMVSPLQPGVRLTALFDSCHSGTVL 307
MVS ++ G +LT + DSCHSG ++
Sbjct: 118 QQFREMVSRVKEGCQLTIISDSCHSGGLI 146
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.130 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,541,851
Number of Sequences: 60738
Number of extensions: 937454
Number of successful extensions: 2793
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2755
Number of HSP's gapped (non-prelim): 21
length of query: 456
length of database: 30,389,216
effective HSP length: 110
effective length of query: 346
effective length of database: 23,708,036
effective search space: 8202980456
effective search space used: 8202980456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)