ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0325 good F KOG1112 Nucleotide transport and metabolism Ribonucleotide reductase, alpha subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0325 109136 111700 855
(855 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER070w [F] KOG1112 Ribonucleotide reductase alpha subunit 882 0.0
YIL066c [F] KOG1112 Ribonucleotide reductase alpha subunit 870 0.0
SPAC1F7.05 [F] KOG1112 Ribonucleotide reductase alpha subunit 859 0.0
CE00331 [F] KOG1112 Ribonucleotide reductase alpha subunit 820 0.0
Hs4506749 [F] KOG1112 Ribonucleotide reductase alpha subunit 817 0.0
At2g21790 [F] KOG1112 Ribonucleotide reductase alpha subunit 810 0.0
7297661 [F] KOG1112 Ribonucleotide reductase alpha subunit 776 0.0
ECU10g0920 [F] KOG1112 Ribonucleotide reductase alpha subunit 689 0.0
>YER070w [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 888
Score = 882 bits (2280), Expect = 0.0
Identities = 451/805 (56%), Positives = 578/805 (71%), Gaps = 25/805 (3%)
Query: 15 KETFNKDKLKKFLQTLTFSLNAEYIELDTLVEKILVGIPNEPTERSKFVSYVAETVAGST 74
KE DK+ + L + L+ ++I+ + ++I+ G+ E + + AET A T
Sbjct: 10 KEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGV-YEGVTTIELDNLAAETCAYMT 68
Query: 75 SAHPDYSILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKITRDLSKNLI 134
+ HPDY+ LAAR+ I LH+ + K +V ED + +I
Sbjct: 69 TVHPDYATLAARIAISNLHK------------QTTKQFSKVVEDLYRYVNAATGKPAPMI 116
Query: 135 SDEFYQYALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETPQFMFMRVA 194
SD+ Y ++ KDK++ AI RD+ ++YFG+KTL +SYL+ R N Q E PQ + MRVA
Sbjct: 117 SDDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLL-RINGQVAERPQHLIMRVA 175
Query: 195 LAIHGPFDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMEDDSIDGIYK 254
L IHG DI++ LET+ LMS KYF HASPTL N+GT +SSCFLV M++DSI+GIY
Sbjct: 176 LGIHGR--DIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYD 233
Query: 255 TLHKTALISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGNKR 314
TL + ALISK +GG+G+H+ NIR+ G+YI+G+NGTSNGL+PM+RVFNNTARYVDQGGNKR
Sbjct: 234 TLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKR 293
Query: 315 PGAFCIYLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENNEDWSIFSP 374
PGAF +YLEPWHADI DF+ +RKNHGKEE+RARDLF ALWIPDLFMKRVE N W++FSP
Sbjct: 294 PGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSP 353
Query: 375 DEAPGLTDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFMLYKDACNK 434
APGL+DCYGDEF+ LY RYEKE K +KAQ++W IL++QTETG PF++YKDACN+
Sbjct: 354 TSAPGLSDCYGDEFEALYTRYEKE-GRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNR 412
Query: 435 KSNQKNLGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVNLSSDG-PPVFDFXXXXX 493
KSNQKNLGVIKSSNLCCEIVEYS+P+E AVCNLASVALP ++ S DG ++F
Sbjct: 413 KSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHE 472
Query: 494 XXXXXXXNLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFMLCRTPFESVDAATLN 553
NL+R ID YPV EAR N+R+RP+A+GVQGLADTFML R PF+S +A LN
Sbjct: 473 IAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLN 532
Query: 554 KQIFETIYHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWSLNKDNYKFLFDDWDSL 613
QIFETIYHA++EAS ELA+ G YE+F GSPAS+G LQFD+W D + DWD+L
Sbjct: 533 IQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMW----DQKPYGMWDWDTL 588
Query: 614 KSRITKGKGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRRVLSGEFTIINQYMVD 673
+ I K G+RNSL + PMPTASTSQILG+ E FEP+TSN+YSRRVLSGEF ++N Y++
Sbjct: 589 RKDIMK-HGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLR 647
Query: 674 DFCQLGIWNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQRKMIDLSSDRAPFID 733
D LGIW+E +K ++ NGSIQ + +P+E+K+LYKTVWE SQ+ +I++++DR+ +ID
Sbjct: 648 DLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYID 707
Query: 734 QSQSLNLYLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAIQFTLNDENTLLDKVT 793
QS SLNL+LR PTMGKLT+MHFY WKKGLKTGMYYLRTQAAS AIQFT++ + + D+ T
Sbjct: 708 QSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQK--IADQAT 765
Query: 794 TKVKDSRPLHPKKFLGQYPKHANDD 818
V D L ++ +A D
Sbjct: 766 ENVADISNLKRPSYMPSSASYAASD 790
>YIL066c [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 869
Score = 870 bits (2248), Expect = 0.0
Identities = 451/828 (54%), Positives = 593/828 (71%), Gaps = 35/828 (4%)
Query: 15 KETFNKDKLKKFLQTLTFSLNAEYIELDTLVEKILVGIPNEPTERSKFVSYVAETVAGST 74
KE DK+ + L++ L+ I+ + ++I+ G+ + T + + AET A T
Sbjct: 10 KEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTT-VELDNLAAETCAYMT 68
Query: 75 SAHPDYSILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKITRDLSKNLI 134
+ HPDY+ LAAR+ I LH+ T+ +K+ + + AT + +I
Sbjct: 69 TVHPDYATLAARIAISNLHK-----QTTKQFSKVIEDLHDWINPATGKHA-------PMI 116
Query: 135 SDEFYQYALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETPQFMFMRVA 194
SDE Y ++ KD ++ AI RD+ +TYFG+KTL +SYL++ N E E PQ + MRVA
Sbjct: 117 SDEIYNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVA-ERPQHLVMRVA 175
Query: 195 LAIHGPFDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMEDDSIDGIYK 254
L IHG DI+SVL+T+ LMS +YF HASPTL N+GT + +SSCFL+ M+DDSI+GIY
Sbjct: 176 LGIHG--SDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYD 233
Query: 255 TLHKTALISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGNKR 314
TL + A+ISK +GGVG+H++NIR+ G+YI+G+NGTSNGL+PM+RVFNNTARYVDQGGNKR
Sbjct: 234 TLKECAMISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKR 293
Query: 315 PGAFCIYLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENNEDWSIFSP 374
PGAF ++LEPWHADI DF+ +RK HGKEE+RARDLF ALWIPDLFMKRV+ + W++FSP
Sbjct: 294 PGAFALFLEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSP 353
Query: 375 DEAPGLTDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFMLYKDACNK 434
APGL D +GDEF++LY RYE+E K +KAQ++W ILQ+QTETG PFM+YKDACN+
Sbjct: 354 SAAPGLDDVWGDEFEELYTRYERE-GRGKTIKAQKLWYAILQAQTETGTPFMVYKDACNR 412
Query: 435 KSNQKNLGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVNLSSDGPPV-FDFXXXXX 493
K+NQ+NLG IKSSNLCCEIVEYSSP+E AVCNLAS+ALP +V +S DG ++F
Sbjct: 413 KTNQQNLGTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVEVSEDGKTASYNFERLHE 472
Query: 494 XXXXXXXNLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFMLCRTPFESVDAATLN 553
NL+R ID YPVPEARN N+++RP+A+GVQGLADT+M+ R PFES +A TLN
Sbjct: 473 IAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFESEEAQTLN 532
Query: 554 KQIFETIYHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWSLNKDNYKFLFDDWDSL 613
KQIFETIYHA +EAS ELA+ G Y +F GSPAS+G LQFD+W+ F DW++L
Sbjct: 533 KQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAK----PFGMWDWETL 588
Query: 614 KSRITKGKGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRRVLSGEFTIINQYMVD 673
+ I K GLRNSL + PMPTASTSQILG+ E FEP+TSN+YSRRVLSGEF ++N Y++
Sbjct: 589 RKDIVK-HGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLR 647
Query: 674 DFCQLGIWNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQRKMIDLSSDRAPFID 733
D LGIW++ +K ++ NGSIQ + +P+E+K LYKTVWE SQ+ +I++++DRA +ID
Sbjct: 648 DLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIYID 707
Query: 734 QSQSLNLYLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAIQFTLNDENTLLDKVT 793
QS SLNL+L+ P+MGK+T+MHFY WKKGLKTGMYYLRTQAAS AIQFT++ E + D+
Sbjct: 708 QSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQE--VADQAA 765
Query: 794 TKVKD----SRPLH-PK--KFLGQYPKHA---NDDNHKADKILPIEDT 831
T + RP++ PK KF Q A + DN K +P E +
Sbjct: 766 THIASVSELDRPVYVPKGTKFSEQKAASALTESSDNEKDASPVPSEQS 813
>SPAC1F7.05 [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 811
Score = 859 bits (2219), Expect = 0.0
Identities = 442/836 (52%), Positives = 582/836 (68%), Gaps = 43/836 (5%)
Query: 21 DKLKKFLQTLTFSLNAEYIELDTLVEKILVGI-PNEPTERSKFVSYVAETVAGSTSAHPD 79
DK+ + L + L++++++ + +K++ G+ P T + + AET A T+ HPD
Sbjct: 16 DKITARVSRLCYGLDSDHVDPVEITQKVISGVYPGVTT--IELDNLAAETAATMTTKHPD 73
Query: 80 YSILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKITRDLSKNLISDEFY 139
Y+ILAAR+ + LH+ + K+ V + D +ISD+ Y
Sbjct: 74 YAILAARIAVSNLHK------------QTEKVFSTVVQQLHDYVNPKTDKPAPMISDKIY 121
Query: 140 QYALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETPQFMFMRVALAIHG 199
+K KD++D AI RD+ + +FG+KTL +SYL+ R + + E PQ M MRVA+ IHG
Sbjct: 122 DIVMKHKDELDSAIIYDRDFTYNFFGFKTLERSYLL-RIDGKVAERPQHMIMRVAVGIHG 180
Query: 200 PFDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMEDDSIDGIYKTLHKT 259
+DI++ +ET+ LMSQ+YF HASPTL N+GT LSSCFLV M+DDSI+GIY TL
Sbjct: 181 --EDIEAAIETYNLMSQRYFTHASPTLFNAGTPRPQLSSCFLVTMKDDSIEGIYDTLKMC 238
Query: 260 ALISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGNKRPGAFC 319
A+ISK +GG+GI++ NIRA G+YI+G+NGTSNG+VPM+RV+NNTARYVDQGGNKRPGAF
Sbjct: 239 AMISKTAGGIGINIHNIRATGSYIAGTNGTSNGIVPMIRVYNNTARYVDQGGNKRPGAFA 298
Query: 320 IYLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENNEDWSIFSPDEAPG 379
YLEPWHAD++DFL+LRK HG E+ RAR++FYALWIPDLFM+RVE NE W+ F P+EAPG
Sbjct: 299 AYLEPWHADVMDFLELRKTHGNEDFRAREMFYALWIPDLFMQRVERNEQWTFFCPNEAPG 358
Query: 380 LTDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFMLYKDACNKKSNQK 439
L D +GDEF LYE+YEKE R+ + AQ++W ILQSQ ETG PFMLYKD+CN+KSNQK
Sbjct: 359 LADVWGDEFVALYEKYEKENRGRRSLPAQKVWYAILQSQVETGNPFMLYKDSCNRKSNQK 418
Query: 440 NLGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVNLSSDGPPVFDFXXXXXXXXXXX 499
N+G I+ SNLC EIVEYSSP+EVAVCNLASVALPT++ DG ++F
Sbjct: 419 NVGTIRCSNLCTEIVEYSSPDEVAVCNLASVALPTFI---KDGK--YNFQKLHDVVKVVT 473
Query: 500 XNLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFMLCRTPFESVDAATLNKQIFET 559
NL++ IDV YPVPEAR N+R+RP+ +GVQGLAD F R PFES A LN QIFET
Sbjct: 474 RNLNKIIDVNYYPVPEARRSNMRHRPVGLGVQGLADAFFALRLPFESAGAKKLNIQIFET 533
Query: 560 IYHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWSLNKDNYKFLFDDWDSLKSRITK 619
IYHAA+EAS E+A++ G YES+ GSPAS+G LQ+D+W++N + DW LK +I K
Sbjct: 534 IYHAALEASCEIAQVEGTYESYEGSPASQGILQYDMWNVNPTD----LWDWAELKEKIAK 589
Query: 620 GKGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRRVLSGEFTIINQYMVDDFCQLG 679
G+RNSLLV PMPTASTSQILGF E FEP TSN+Y RRVLSGEF I+N +++ D +
Sbjct: 590 -HGIRNSLLVAPMPTASTSQILGFNECFEPYTSNMYQRRVLSGEFQIVNPWLLKDLVERD 648
Query: 680 IWNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQRKMIDLSSDRAPFIDQSQSLN 739
+WNE +KN+++ +GSIQ I IP+++K+LYKTVWE SQ+ +ID ++DR PFIDQSQSLN
Sbjct: 649 LWNEDMKNKLVMLDGSIQAIPEIPQDLKDLYKTVWEISQKTVIDYAADRGPFIDQSQSLN 708
Query: 740 LYLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAIQFTLNDENTLLDKVTTKVKDS 799
++L++P+ GK+T+MHFY WKKGLKTGMYYLRT AAS AI+FT +D V + ++
Sbjct: 709 IHLKDPSYGKITSMHFYGWKKGLKTGMYYLRTMAASAAIKFT-------VDPVALRARNE 761
Query: 800 RPLHPKKFLGQYPKHANDDNHKAD-KILPIEDTYGIHDSTPLVCNIIEGSTCESCS 854
+ K N KA+ P ++ I++ L C+I CE CS
Sbjct: 762 ES-------NEENKKPVIKNGKAEISAEPTKEEIDIYNEKVLACSIKNPEACEMCS 810
>CE00331 [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 788
Score = 820 bits (2117), Expect = 0.0
Identities = 415/774 (53%), Positives = 551/774 (70%), Gaps = 26/774 (3%)
Query: 15 KETFNKDKLKKFLQTLTFSLNAEYIELDTLVEKILVGIPNEPTERSKFVSYVAETVAGST 74
KE + DK+ +Q L++ LN ++++ + K++ G+ T + + AET A T
Sbjct: 16 KEDVHFDKITSRIQKLSYGLNMDFVDPVAVAIKVISGLYKGVTT-VELDNLAAETAASMT 74
Query: 75 SAHPDYSILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKITRDLSKNLI 134
+ HP+Y++LAAR+ + LH+ K K+ EV + + +I
Sbjct: 75 TQHPEYALLAARIAVSNLHK------------KTNKVFSEVMKTLHEFHHPHTGKHAPMI 122
Query: 135 SDEFYQYALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETPQFMFMRVA 194
SDE + K DK++ AI RDY++TYFG+KTL +SYL+K N E E PQ M MRV+
Sbjct: 123 SDETWAIIEKNADKLNSAIVYDRDYSYTYFGFKTLERSYLLKINKEIV-ERPQQMLMRVS 181
Query: 195 LAIHGPFDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMEDDSIDGIYK 254
+ IHG DDI S +ET+ LMS++Y HASPTL NSGT +SSCFL+ M +DSI GIY
Sbjct: 182 IGIHG--DDITSAIETYNLMSERYMTHASPTLFNSGTCRPQMSSCFLLTMSEDSILGIYD 239
Query: 255 TLHKTALISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGNKR 314
TL + ALISK++GG+G++V IRA G+ I+G+NGTSNGL+PMLRV+NNTARYVDQGGNKR
Sbjct: 240 TLKQCALISKSAGGIGLNVHKIRATGSVIAGTNGTSNGLIPMLRVYNNTARYVDQGGNKR 299
Query: 315 PGAFCIYLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENNEDWSIFSP 374
PGAF IYLEPWHADI +F+ LRKN G EE RARDLF ALWIPDLFMKRVE +++WS+ P
Sbjct: 300 PGAFAIYLEPWHADIFEFVSLRKNTGPEEERARDLFLALWIPDLFMKRVEKDQEWSLMCP 359
Query: 375 DEAPGLTDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFMLYKDACNK 434
E PGL DC+G+EF+ LY +YE E RK +KA+++W I+ +Q ETG+P++ YKDA N+
Sbjct: 360 CECPGLDDCWGEEFEALYAKYEAEGRVRKTVKARKLWEHIVSNQIETGLPYITYKDAANR 419
Query: 435 KSNQKNLGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVNLSSDGPPVFDFXXXXXX 494
KSNQ+NLG IK SNLC EI+EYS+P+E+AVCNLAS+AL YV FDF
Sbjct: 420 KSNQQNLGTIKCSNLCTEIIEYSAPDEIAVCNLASIALNRYVTPEKK----FDFVKLAEV 475
Query: 495 XXXXXXNLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFMLCRTPFESVDAATLNK 554
NL++ IDV YPV EARN N+R+RP+ +GVQGLAD FML R PF S +A LNK
Sbjct: 476 TKVITRNLNKIIDVNYYPVEEARNSNMRHRPIGLGVQGLADCFMLMRYPFTSAEARDLNK 535
Query: 555 QIFETIYHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWSLNKDNYKFLFDDWDSLK 614
+IFETIY+AA+EAS ELAEL G Y ++ GSP S+GQLQFD+W + + DW +L+
Sbjct: 536 RIFETIYYAALEASCELAELNGPYSTYEGSPVSKGQLQFDMWGVTPTDQ----CDWATLR 591
Query: 615 SRITKGKGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRRVLSGEFTIINQYMVDD 674
+I K G+RNSLL+ PMPTAST+QILG ES EP TSNIYSRRVLSG+F I+N +M+ D
Sbjct: 592 KKIAK-HGIRNSLLMAPMPTASTAQILGNNESIEPYTSNIYSRRVLSGDFQIVNPHMLKD 650
Query: 675 FCQLGIWNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQRKMIDLSSDRAPFIDQ 734
+ G+W +++KNR++ +NGSIQ I+GIP ++K LY+TVWE SQ+ +I++++DR +IDQ
Sbjct: 651 LVERGLWTDEMKNRLIANNGSIQNIDGIPSDIKELYRTVWEISQKDIIEMAADRGAYIDQ 710
Query: 735 SQSLNLYLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAIQFTLNDENTL 788
SQSLN+++ +P+ +T+MHFY WKKGLKTGMYYLRT+ A A+QFT+ D+N L
Sbjct: 711 SQSLNIHMAKPSYAGITSMHFYGWKKGLKTGMYYLRTKPAVNAVQFTV-DKNAL 763
>Hs4506749 [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 792
Score = 817 bits (2110), Expect = 0.0
Identities = 416/771 (53%), Positives = 551/771 (70%), Gaps = 26/771 (3%)
Query: 21 DKLKKFLQTLTFSLNAEYIELDTLVEKILVGIPNEPTERSKFVSYVAETVAGSTSAHPDY 80
DK+ +Q L + LN ++++ + K++ G+ + T + + AET A T+ HPDY
Sbjct: 16 DKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTT-VELDTLAAETAATLTTKHPDY 74
Query: 81 SILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKITRDLSKNLISDEFYQ 140
+ILAAR+ + LH+ + +K+ +V ED +++
Sbjct: 75 AILAARIAVSNLHK------------ETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLD 122
Query: 141 YALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETPQFMFMRVALAIHGP 200
L KD+++ AI RD+++ YFG+KTL +SYL+K N + E PQ M MRV++ IH
Sbjct: 123 IVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVA-ERPQHMLMRVSVGIHK- 180
Query: 201 FDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMEDDSIDGIYKTLHKTA 260
+DID+ +ET+ L+S+++F HASPTL N+GT LSSCFL+ M+DDSI+GIY TL + A
Sbjct: 181 -EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCA 239
Query: 261 LISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGNKRPGAFCI 320
LISK++GG+G+ VS IRA G+YI+G+NG SNGLVPMLRV+NNTARYVDQGGNKRPGAF I
Sbjct: 240 LISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAI 299
Query: 321 YLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENNEDWSIFSPDEAPGL 380
YLEPWH DI +FL L+KN GKEE RARDLF+ALWIPDLFMKRVE N+DWS+ P+E PGL
Sbjct: 300 YLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGL 359
Query: 381 TDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFMLYKDACNKKSNQKN 440
+ +G+EF+KLY YEK+ RK +KAQQ+W I++SQTETG P+MLYKD+CN+KSNQ+N
Sbjct: 360 DEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQN 419
Query: 441 LGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVNLSSDGPPVFDFXXXXXXXXXXXX 500
LG IK SNLC EIVEY+S +EVAVCNLAS+AL YV +DF
Sbjct: 420 LGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVT----SEHTYDFKKLAEVTKVVVR 475
Query: 501 NLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFMLCRTPFESVDAATLNKQIFETI 560
NL++ ID+ YPVPEA N R+RP+ IGVQGLAD F+L R PFES +A LNKQIFETI
Sbjct: 476 NLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETI 535
Query: 561 YHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWSLNKDNYKFLFDDWDSLKSRITKG 620
Y+ A+EAS +LA+ G YE++ GSP S+G LQ+D+W++ + DW LK +I K
Sbjct: 536 YYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTD----LWDWKVLKEKIAK- 590
Query: 621 KGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRRVLSGEFTIINQYMVDDFCQLGI 680
G+RNSLL+ PMPTAST+QILG ES EP TSNIY+RRVLSGEF I+N +++ D + G+
Sbjct: 591 YGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGL 650
Query: 681 WNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQRKMIDLSSDRAPFIDQSQSLNL 740
W+E++KN+I+ NGSIQ+I IP+++K LYKTVWE SQ+ ++ ++++R FIDQSQSLN+
Sbjct: 651 WHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNI 710
Query: 741 YLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAIQFTLNDENTLLDK 791
++ EP GKLT+MHFY WK+GLKTGMYYLRT+ A+ IQFTLN E L DK
Sbjct: 711 HIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK-LKDK 760
>At2g21790 [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 816
Score = 810 bits (2091), Expect = 0.0
Identities = 411/785 (52%), Positives = 551/785 (69%), Gaps = 38/785 (4%)
Query: 15 KETFNKDKLKKFLQTLTFSLNAEYIELDTLVEKILVGIPNEPTERSKFVSYVAETVAGST 74
+ET + DK+ L+ L++ L++++ + + +K+ G+ T S+ AET A T
Sbjct: 10 QETVHFDKITARLKKLSYGLSSDHCDPVLVAQKVCAGVYKGVTT-SQLDELAAETAAAMT 68
Query: 75 SAHPDYSILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKITRDLSKNLI 134
HPDY+ LAAR+ + LH+ +K E +D L LI
Sbjct: 69 CNHPDYASLAARIAVSNLHK------------NTKKSFSETIKDMFYHVNDRSGLKSPLI 116
Query: 135 SDEFYQYALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETPQFMFMRVA 194
+D+ ++ ++ ++D I RD+ + YFG+KTL +SYL+K E PQ M MRVA
Sbjct: 117 ADDVFEIIMQNAARLDSEIIYDRDFEYDYFGFKTLERSYLLKVQGTVV-ERPQHMLMRVA 175
Query: 195 LAIHGPFDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMEDDSIDGIYK 254
+ IH DDIDSV++T+ LMSQ++F HASPTL N+GT LSSCFLV M+DDSI+GIY+
Sbjct: 176 VGIHK--DDIDSVIQTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKDDSIEGIYE 233
Query: 255 TLHKTALISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGNKR 314
TL + A+ISK++GG+G+ V NIRA G+YI G+NGTSNG+VPMLRVFN+TARYVDQGG KR
Sbjct: 234 TLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKR 293
Query: 315 PGAFCIYLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENNEDWSIFSP 374
GAF +YLEPWHAD+ +FL+LRKNHGKEE RARDLFYALW+PDLFM+RV+NN WS+F P
Sbjct: 294 KGAFAVYLEPWHADVYEFLELRKNHGKEEHRARDLFYALWLPDLFMERVQNNGQWSLFCP 353
Query: 375 DEAPGLTDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFMLYKDACNK 434
+EAPGL DC+G EF+ LY +YE+E +K ++AQQ+W EIL SQ ETG P+ML+KD+CN+
Sbjct: 354 NEAPGLADCWGAEFETLYTKYEREGKAKKVVQAQQLWYEILTSQVETGTPYMLFKDSCNR 413
Query: 435 KSNQKNLGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVN-----LSSDGPPV---- 485
KSNQ+NLG IKSSNLC EI+EY+SP E AVCNLAS+ALP +V L S P +
Sbjct: 414 KSNQQNLGTIKSSNLCTEIIEYTSPTETAVCNLASIALPRFVREKGVPLDSHPPKLAGSL 473
Query: 486 ------FDFXXXXXXXXXXXXNLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFML 539
FDF NL++ IDV YPV A+ N+R+RP+ IGVQGLAD F+L
Sbjct: 474 DSKNRYFDFEKLAEVTATVTVNLNKIIDVNYYPVETAKTSNMRHRPIGIGVQGLADAFIL 533
Query: 540 CRTPFESVDAATLNKQIFETIYHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWS-L 598
PF+S +A LNK IFETIY+ A++ASTELA G YE++ GSP S+G LQ D+W+ +
Sbjct: 534 LGMPFDSPEAQQLNKDIFETIYYHALKASTELAARLGPYETYAGSPVSKGILQPDMWNVI 593
Query: 599 NKDNYKFLFDDWDSLKSRITKGKGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRR 658
D + DW L+ I+K G+RNSLLV PMPTASTSQILG E FEP TSNIYSRR
Sbjct: 594 PSDRW-----DWAVLRDMISK-NGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRR 647
Query: 659 VLSGEFTIINQYMVDDFCQLGIWNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQ 718
VLSGEF ++N++++ D +G+W LKN+++ +NGSI + IP+++K +Y+TVWE Q
Sbjct: 648 VLSGEFVVVNKHLLHDLTDMGLWTPTLKNKLINENGSIVNVAEIPDDLKAIYRTVWEIKQ 707
Query: 719 RKMIDLSSDRAPFIDQSQSLNLYLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAI 778
R ++D+++DR +IDQSQSLN+++ +P KLT++HFYTWKKGLKTGMYYLR++AA+ AI
Sbjct: 708 RTVVDMAADRGCYIDQSQSLNIHMDKPNFAKLTSLHFYTWKKGLKTGMYYLRSRAAADAI 767
Query: 779 QFTLN 783
+FT++
Sbjct: 768 KFTVD 772
>7297661 [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 771
Score = 776 bits (2004), Expect = 0.0
Identities = 387/717 (53%), Positives = 511/717 (70%), Gaps = 24/717 (3%)
Query: 67 AETVAGSTSAHPDYSILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKIT 126
AE AG T HPDY+ILAAR+ + LH+ + +K +V ED
Sbjct: 31 AEIAAGLTCNHPDYAILAARIAVSNLHK------------ETKKAFSDVFEDLYNHVNKE 78
Query: 127 RDLSKNLISDEFYQYALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETP 186
+ L+S+ Y K +++ +I RD+ + YFG+KTL +SYL+KRN + E P
Sbjct: 79 TNQKVPLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIA-ERP 137
Query: 187 QFMFMRVALAIHGPFDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMED 246
Q M MRVA+ IHG +DID+ +ET+ L+S++YF HASPTL + T LSSCFL+ M
Sbjct: 138 QHMLMRVAIGIHG--EDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTA 195
Query: 247 DSIDGIYKTLHKTALISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARY 306
DSI+GI+K++ + A+ISK++GG+G++V IRA G I G+NGTSNGLVPMLRVFNN ARY
Sbjct: 196 DSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARY 255
Query: 307 VDQGGNKRPGAFCIYLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENN 366
VDQGG KRPGAF IYLEPWH+D+ +FL+L+KN GKEE RARDLFYALWIPDLFMKRVE N
Sbjct: 256 VDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEAN 315
Query: 367 EDWSIFSPDEAPGLTDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFM 426
DWS+ P + PGL D +GDEF+KLYE+YE+E + +KAQ +W I+++Q ETG P+M
Sbjct: 316 GDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYM 375
Query: 427 LYKDACNKKSNQKNLGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVNLSSDGPPVF 486
L+KDACN+KSNQ+N+G IK SNLC EIVEYS+P+E+AVCNLAS+AL +V +
Sbjct: 376 LFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFVTPEK----TY 431
Query: 487 DFXXXXXXXXXXXXNLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFMLCRTPFES 546
DF NL++ ID+ YP+PEAR N+R+RP+ IG+QG AD +L R P+ES
Sbjct: 432 DFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYES 491
Query: 547 VDAATLNKQIFETIYHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWSLNKDNYKFL 606
+A LN+QIFETIY+ A+EAS ELA+ G YE++ GSP S+G LQ+D+W D
Sbjct: 492 EEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMW----DKVPTN 547
Query: 607 FDDWDSLKSRITKGKGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRRVLSGEFTI 666
DW LK I + G+RNSLLV PMPTAST+QI+G ESFEP T+NIY+RRVLSGEF +
Sbjct: 548 LWDWQKLKESI-RMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQV 606
Query: 667 INQYMVDDFCQLGIWNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQRKMIDLSS 726
+N +++ D +L +W++ +KN+I+ GSIQ IE IP +V++LYKTVWE S + I +++
Sbjct: 607 VNHHLLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAA 666
Query: 727 DRAPFIDQSQSLNLYLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAIQFTLN 783
DR FIDQSQS N+++ EP GKLT++HFY+WK GLKTGMYYLRT+ A+ AIQFT+N
Sbjct: 667 DRGAFIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVN 723
>ECU10g0920 [F] KOG1112 Ribonucleotide reductase alpha subunit
Length = 768
Score = 689 bits (1778), Expect = 0.0
Identities = 359/785 (45%), Positives = 514/785 (64%), Gaps = 39/785 (4%)
Query: 16 ETFNKDKLKKFLQTLTFSLNAEYIELDTLVEKILVGIPNEPTERSKFVSYVAETVAGSTS 75
E D ++ ++ L ++++D LVE+I+ G + T R + + Y +ET A +
Sbjct: 13 EKLGIDLIRSRIEGYVKDLKLRHVDVDELVERIVSGWCEDMT-RKETIDYCSETAASMIT 71
Query: 76 AHPDYSILAARVEIRELHRIIGDATFTENLAKLRKISREVTEDATKRRKITRDLSKNLIS 135
HP+Y +++R+ + +H I D+ F E + ++K + ++S
Sbjct: 72 KHPEYGQISSRIIVSYIHEITMDS-FVEKIKYIQK-------------------HRGMVS 111
Query: 136 DEFYQYALKFKDKIDQAIDKSRDYNFTYFGWKTLCKSYLMKRNNEQTHETPQFMFMRVAL 195
+E Y L+ + I+ I+ D+ F+YFG TL KSYL+K E+ E PQ MFMRVAL
Sbjct: 112 EEMYGIILEHGETIEGMINYENDFLFSYFGILTLMKSYLIKVG-EEIIERPQDMFMRVAL 170
Query: 196 AIHGPFDDIDSVLETFELMSQKYFIHASPTLCNSGTVNQYLSSCFLVGMEDDSIDGIYKT 255
IH D + V E + L+S YF HA+PTL NS N L+SCFL+ +DSI+G+Y
Sbjct: 171 QIHKT--DFEKVREVYNLLSGHYFTHATPTLYNSCLKNPQLASCFLITPREDSIEGVYHM 228
Query: 256 LHKTALISKASGGVGIHVSNIRANGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGNKRP 315
+++ A+I+K SGG+G+++ IR+ G+ + + G SNG++P+++V N T RY++QG +RP
Sbjct: 229 INQAAIITKYSGGIGLNLHGIRSKGSSLRSTGGRSNGIIPLIQVLNATKRYINQGAERRP 288
Query: 316 GAFCIYLEPWHADIIDFLQLRKNHGKEEMRARDLFYALWIPDLFMKRVENNEDWSIFSPD 375
G+ I+LEPWH +I DFL+LRKN G EE RARD+F ALWI DLFM+RV+NNE+WS+F P
Sbjct: 289 GSIAIFLEPWHMEIFDFLELRKNTGPEEFRARDIFTALWINDLFMERVKNNEEWSLFCPS 348
Query: 376 EAPGLTDCYGDEFDKLYERYEKELIPRKKMKAQQIWSEILQSQTETGVPFMLYKDACNKK 435
+A GL+D +G+EF+ LY +YEK I R + AQ++W I+++Q ETG P+M YKDACN+
Sbjct: 349 QAVGLSDVWGEEFNALYCKYEK-TISRTVVPAQKLWKAIIEAQIETGTPYMCYKDACNRL 407
Query: 436 SNQKNLGVIKSSNLCCEIVEYSSPEEVAVCNLASVALPTYVNLSSDGPPVFDFXXXXXXX 495
SNQ++LG IKSSNLC EIVEYSS EE +VCNLAS+ LP +V DG FDF
Sbjct: 408 SNQQHLGTIKSSNLCAEIVEYSSGEETSVCNLASICLPMFV---KDG--WFDFEAFRRVV 462
Query: 496 XXXXXNLDRTIDVGKYPVPEARNGNIRNRPLAIGVQGLADTFMLCRTPFESVDAATLNKQ 555
NL+R ID YPV EAR N+RNRP+ IGVQGLAD F + R FES A +LN+
Sbjct: 463 KILTVNLNRVIDFNYYPVEEARRSNMRNRPIGIGVQGLADLFAILRLAFESDGARSLNQD 522
Query: 556 IFETIYHAAIEASTELAELFGHYESFPGSPASEGQLQFDLWSLN-KDNYKFLFDDWDSLK 614
IFE +Y++A+EAS ELAE G + S+ GSP S+G F+L N+ DW+ L+
Sbjct: 523 IFEAMYYSAMEASCELAEKEGPFPSYEGSPISKGIFHFELAGRKASGNW-----DWEGLR 577
Query: 615 SRITKGKGLRNSLLVGPMPTASTSQILGFTESFEPMTSNIYSRRVLSGEFTIINQYMVDD 674
RI + G+RNSLL+ MPTA TSQI G E+FEP SNIY+RR +GEF I+NQ++V+D
Sbjct: 578 ERIRR-HGVRNSLLIALMPTAGTSQIFGNNEAFEPHASNIYTRRTHAGEFQIVNQHLVND 636
Query: 675 FCQLGIWNEKLKNRILRDNGSIQTIEGIPEEVKNLYKTVWETSQRKMIDLSSDRAPFIDQ 734
+LG+W+ ++KN ++ + GSIQ I IP E++ +YKT WE + +IDL++DR F+DQ
Sbjct: 637 LVRLGLWSYEMKNLVIENEGSIQNITSIPHEIREIYKTAWEIKMKSVIDLAADRQVFVDQ 696
Query: 735 SQSLNLYLREPTMGKLTAMHFYTWKKGLKTGMYYLRTQAASRAIQFTLNDENTLLDKVTT 794
SQSLN+++ +PT +LT+MHFY + GLKTGMYYLRT+ + AI+FT+ + L +K +
Sbjct: 697 SQSLNIFIAKPTYSQLTSMHFYGYHCGLKTGMYYLRTRPITSAIKFTV--DKKLAEKTLS 754
Query: 795 KVKDS 799
+ D+
Sbjct: 755 SMNDT 759
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,434,190
Number of Sequences: 60738
Number of extensions: 2311511
Number of successful extensions: 5523
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5467
Number of HSP's gapped (non-prelim): 10
length of query: 855
length of database: 30,389,216
effective HSP length: 115
effective length of query: 740
effective length of database: 23,404,346
effective search space: 17319216040
effective search space used: 17319216040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)