ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0333 good E KOG2467 Amino acid transport and metabolism Glycine/serine hydroxymethyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0333 112835 114328 498
(498 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR263w [E] KOG2467 Glycine/serine hydroxymethyltransferase 687 0.0
SPAC18G6.04c [E] KOG2467 Glycine/serine hydroxymethyltransferase 559 e-159
YLR058c [E] KOG2467 Glycine/serine hydroxymethyltransferase 546 e-155
SPAC24C9.12c [E] KOG2467 Glycine/serine hydroxymethyltransferase 542 e-154
At4g37930 [E] KOG2467 Glycine/serine hydroxymethyltransferase 529 e-150
CE01130 [E] KOG2467 Glycine/serine hydroxymethyltransferase 516 e-146
At5g26780 [E] KOG2467 Glycine/serine hydroxymethyltransferase 512 e-145
At4g32520 [E] KOG2467 Glycine/serine hydroxymethyltransferase 494 e-140
7290652 [E] KOG2467 Glycine/serine hydroxymethyltransferase 491 e-138
Hs20070176 [E] KOG2467 Glycine/serine hydroxymethyltransferase 483 e-136
Hs19923315 [E] KOG2467 Glycine/serine hydroxymethyltransferase 480 e-135
At4g13930 [E] KOG2467 Glycine/serine hydroxymethyltransferase 455 e-128
At4g13890 [E] KOG2467 Glycine/serine hydroxymethyltransferase 439 e-123
At1g22020 [E] KOG2467 Glycine/serine hydroxymethyltransferase 411 e-114
ECU01g1420 [E] KOG2467 Glycine/serine hydroxymethyltransferase 410 e-114
ECU01g0190 [E] KOG2467 Glycine/serine hydroxymethyltransferase 410 e-114
At1g36370 [E] KOG2467 Glycine/serine hydroxymethyltransferase 405 e-113
>YBR263w [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 565
Score = 687 bits (1772), Expect = 0.0
Identities = 336/481 (69%), Positives = 392/481 (80%)
Query: 18 RSLASQANTGANASANQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVM 77
+ +A+ G S Q +VSK V + DPEM+DIL +ER RQKHSITLIPSENFTSK+VM
Sbjct: 85 KCMATVHRRGLLTSGAQSLVSKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVM 144
Query: 78 DLLGSEMQNKYSEGYPGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAP 137
DLLGSE+QNKYSEGYPGERYYGGN+ ID +ESLCQ RALELY LDP WGVNVQPLSGAP
Sbjct: 145 DLLGSELQNKYSEGYPGERYYGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAP 204
Query: 138 ANLYAYSAVMETNDRLMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGII 197
ANLY YSA+M +RLMGLDLP GGHLSHGYQL SGT IS+ISKYFQ+MPYHVD TG+I
Sbjct: 205 ANLYVYSAIMNVGERLMGLDLPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLI 264
Query: 198 DYDFLSKTSKLFRPKVIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVT 257
DYD L +K FRPKVIVAG SAYSR++DY RFKEI+ CGAYLMSDMAHISGLVAA V
Sbjct: 265 DYDNLQVLAKAFRPKVIVAGTSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVV 324
Query: 258 RSPFEYSDIVTTTTHKSLRGPRGAMIFYXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQG 317
SPFE+SDIVTTTTHKSLRGPRGAMIF+ E+ Y+L+K+INFSVFPGHQG
Sbjct: 325 PSPFEHSDIVTTTTHKSLRGPRGAMIFFRKGIKSVTKKGKEIPYELEKKINFSVFPGHQG 384
Query: 318 GPHNHTISALAVALKQAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTDTHLILIN 377
GPHNHTI A+AVALKQA +PEFKEYQ +V+N++ F +EL K G++LVSGGTD HLI+I+
Sbjct: 385 GPHNHTIGAMAVALKQAMSPEFKEYQQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVID 444
Query: 378 LSNLGIDGARLETLLENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVA 437
LS +DGAR+ET+L +NIAANKNTIPGDKSALFPSGLR+GTPAMTTRGFG +EF+QVA
Sbjct: 445 LSGTQVDGARVETILSALNIAANKNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVA 504
Query: 438 AYIDRAVKLAIGIKSQESPDAKDARSKLASFKELCKESDQVKQLADEVYQWVGEFPVPGE 497
YID AVKLA +K+ E DARS+L FK+LC ES +V L+ E+ +WVG++PVPG+
Sbjct: 505 KYIDSAVKLAENLKTLEPTTKLDARSRLNEFKKLCNESSEVAALSGEISKWVGQYPVPGD 564
Query: 498 L 498
+
Sbjct: 565 I 565
>SPAC18G6.04c [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 472
Score = 559 bits (1441), Expect = e-159
Identities = 278/456 (60%), Positives = 338/456 (73%), Gaps = 7/456 (1%)
Query: 43 DIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQ 102
+ DP +Y IL E+ RQK SI LI SENFTS++VMD LGS MQNKYSEGYPG RYYGGN+
Sbjct: 20 ECDPTVYKILESEKSRQKESIALIASENFTSRAVMDALGSIMQNKYSEGYPGARYYGGNE 79
Query: 103 FIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGG 162
FID AE LCQ RALE ++LD + WGVNVQP SG+PANL AY AVM+ +DRLMGLDLPHGG
Sbjct: 80 FIDQAERLCQTRALEAFHLDGEKWGVNVQPHSGSPANLQAYQAVMKPHDRLMGLDLPHGG 139
Query: 163 HLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYS 222
HLSHG+ P IS +S YF TMPY+V+ +TGIIDYD L K + FRPKVIVAGASAY+
Sbjct: 140 HLSHGFSTPQKA-ISAVSTYFSTMPYNVNKETGIIDYDSLEKAAIQFRPKVIVAGASAYA 198
Query: 223 RVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAM 282
R++DYKR ++I + C AYL+ DMAHISGLVAAGV SPFEY+DIVTTTTHKSLRGPRGAM
Sbjct: 199 RLVDYKRMRKITEMCNAYLLCDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRGAM 258
Query: 283 IFYXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEY 342
IFY +LY+L+ +INFSVFPGHQGGPHNHTI+ALAVAL QA TPEF +Y
Sbjct: 259 IFYRKGTRSHDKRGNPILYELEDKINFSVFPGHQGGPHNHTITALAVALGQAKTPEFYQY 318
Query: 343 QAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKN 402
Q V+ NA+ + +G++LVSGGTDTHL+L++L++ G+DGAR+E +LE +NI+ANKN
Sbjct: 319 QKDVLSNAKAMANAFITRGYKLVSGGTDTHLVLVDLTDKGVDGARVERILELVNISANKN 378
Query: 403 TIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDAKDAR 462
T+PGDKSAL P GLR+GTPA TTRGF ++F +V ID V L K K+ +
Sbjct: 379 TVPGDKSALIPRGLRLGTPACTTRGFDEKDFERVVELIDEVVSLT---KKINEAALKEGK 435
Query: 463 SKLASFKELCKES---DQVKQLADEVYQWVGEFPVP 495
SK FK + ++ +L EV W G+F P
Sbjct: 436 SKFRDFKAYVGDGSKFSEIAKLKKEVITWAGKFDFP 471
>YLR058c [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 469
Score = 546 bits (1408), Expect = e-155
Identities = 273/467 (58%), Positives = 341/467 (72%), Gaps = 7/467 (1%)
Query: 30 ASANQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYS 89
+ A+ +++ H+ D DPE+ I+ E +RQKHSI LI SENFTS SV D LG+ + NKYS
Sbjct: 6 SDAHHKLITSHLVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPLSNKYS 65
Query: 90 EGYPGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMET 149
EGYPG RYYGGN+ ID E LCQ+RAL+ +++ P WGVNVQ LSG+PANL Y A+M+
Sbjct: 66 EGYPGARYYGGNEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQAIMKP 125
Query: 150 NDRLMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLF 209
++RLMGL LP GGHLSHGY + KIS +S YF++ PY V+ +TGIIDYD L K + L+
Sbjct: 126 HERLMGLYLPDGGHLSHGYATEN-RKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILY 184
Query: 210 RPKVIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTT 269
RPKV+VAG SAY R++DYKR +EIAD CGAYLM DMAHISGL+AAGV SPFEY+DIVTT
Sbjct: 185 RPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLIAAGVIPSPFEYADIVTT 244
Query: 270 TTHKSLRGPRGAMIFYXXXXXXXX-XXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALA 328
TTHKSLRGPRGAMIF+ EVLYDL+ INFSVFPGHQGGPHNHTI+ALA
Sbjct: 245 TTHKSLRGPRGAMIFFRRGVRSINPKTGKEVLYDLENPINFSVFPGHQGGPHNHTIAALA 304
Query: 329 VALKQAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARL 388
ALKQAATPEFKEYQ V++NA+ E G+ LVS GTD+H++L++L G+DGAR+
Sbjct: 305 TALKQAATPEFKEYQTQVLKNAKALESEFKNLGYRLVSNGTDSHMVLVSLREKGVDGARV 364
Query: 389 ETLLENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAI 448
E + E INIA NKN+IPGDKSAL P G+R+G PAMTTRG G ++F ++ YI++AV+ A
Sbjct: 365 EYICEKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQ 424
Query: 449 GIKSQESPDAKDARSKLASFKELCKE-SDQVKQLADEVYQWVGEFPV 494
++ DA +L FK E SD + E+Y W GE+P+
Sbjct: 425 QVQQSLPKDA----CRLKDFKAKVDEGSDVLNTWKKEIYDWAGEYPL 467
>SPAC24C9.12c [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 467
Score = 542 bits (1397), Expect = e-154
Identities = 268/467 (57%), Positives = 342/467 (72%), Gaps = 8/467 (1%)
Query: 31 SANQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSE 90
S+N ++ +++ DP + +I+ E RQ+ S+ LI SENFTS++VMD LGS M NKYSE
Sbjct: 2 SSNDSIMLTPLKEQDPTVAEIMRHEADRQRSSVVLIASENFTSRAVMDALGSVMSNKYSE 61
Query: 91 GYPGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETN 150
GYPG RYYGGN+FID E+LCQ+RAL +NLDP WGVNVQ LSG+PAN+ Y A+M +
Sbjct: 62 GYPGARYYGGNKFIDQIETLCQERALAAFNLDPAKWGVNVQCLSGSPANMQVYQAIMPPH 121
Query: 151 DRLMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFR 210
RLMGLDLP GGHLSHGYQ + KIS +S YF++MPY VD TG+IDYD L ++LFR
Sbjct: 122 GRLMGLDLPSGGHLSHGYQTDT-KKISAVSTYFESMPYRVDPNTGLIDYDMLEHDAQLFR 180
Query: 211 PKVIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTT 270
PK++VAG SAY R++DY R ++IAD+ AYL+ DMAHISGLV+AGV SPFEY+D+VTTT
Sbjct: 181 PKILVAGTSAYCRLIDYARMRQIADSVNAYLVVDMAHISGLVSAGVIPSPFEYADVVTTT 240
Query: 271 THKSLRGPRGAMIFYXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVA 330
THKSLRGPRGAMIF+ + YDL+ +INFSVFPGHQGGPHNHTI+ALAVA
Sbjct: 241 THKSLRGPRGAMIFFRRGLRKHDKKGNPIYYDLEDKINFSVFPGHQGGPHNHTITALAVA 300
Query: 331 LKQAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLET 390
LKQ P +KEYQA VV+NA++ EE K+G++L + GTD+H++L+++ + G+DGAR E
Sbjct: 301 LKQCQEPAYKEYQAQVVKNAKVCEEEFKKRGYKLAADGTDSHMVLVDVKSKGVDGARAER 360
Query: 391 LLENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGI 450
+LE INI NKNT+P DKSA PSG+RVGTPAMTTRGF Q+F +V YIDRA+ A +
Sbjct: 361 VLELINIVTNKNTVPSDKSAFSPSGIRVGTPAMTTRGFKEQDFVRVVDYIDRALTFAANL 420
Query: 451 KSQESPDAKDARSKLASFKELCKESDQ---VKQLADEVYQWVGEFPV 494
+ + DA +KL FK E +Q + QL EV +W FP+
Sbjct: 421 QKELPKDA----NKLKDFKAKLGEGEQYPELVQLQKEVAEWASSFPL 463
>At4g37930 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 517
Score = 529 bits (1362), Expect = e-150
Identities = 257/457 (56%), Positives = 345/457 (75%), Gaps = 5/457 (1%)
Query: 41 VQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGG 100
++++DPE+ DI+ E+ RQ + LIPSENFTS SVM +GS M NKYSEGYPG RYYGG
Sbjct: 55 LEEVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGG 114
Query: 101 NQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPH 160
N++IDMAE+LCQKRALE + LDP+ WGVNVQPLSG+PAN + Y+A+++ ++R+M LDLPH
Sbjct: 115 NEYIDMAETLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALDLPH 174
Query: 161 GGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASA 220
GGHLSHGYQ + KIS +S +F+TMPY +D TG IDYD + K++ LFRPK+IVAGASA
Sbjct: 175 GGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGYIDYDQMEKSATLFRPKLIVAGASA 233
Query: 221 YSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRG 280
Y+R+ DY R +++ + A +++DMAHISGLVAA V SPF+Y+D+VTTTTHKSLRGPRG
Sbjct: 234 YARLYDYARIRKVCNKQKAVMLADMAHISGLVAANVIPSPFDYADVVTTTTHKSLRGPRG 293
Query: 281 AMIFYXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFK 340
AMIF+ EVLYD + +IN +VFPG QGGPHNHTI+ LAVALKQA T E+K
Sbjct: 294 AMIFFRKGVKEINKQGKEVLYDFEDKINQAVFPGLQGGPHNHTITGLAVALKQATTSEYK 353
Query: 341 EYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAAN 400
YQ V+ N+ F + L+++G+ELVSGGTD HL+L+NL GIDG+R+E +LE ++IA+N
Sbjct: 354 AYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIASN 413
Query: 401 KNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQ-ESPDAK 459
KNT+PGD SA+ P G+R+GTPA+T+RGF ++FA+VA Y D+AV +A+ +KS+ + K
Sbjct: 414 KNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTKLK 473
Query: 460 DARSKLASFKELCKESDQVKQLADEVYQWVGEFPVPG 496
D S + S + ++ +L EV ++ +FP G
Sbjct: 474 DFVSAMESSSTI---QSEIAKLRHEVEEFAKQFPTIG 507
>CE01130 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 484
Score = 516 bits (1328), Expect = e-146
Identities = 252/464 (54%), Positives = 337/464 (72%), Gaps = 4/464 (0%)
Query: 33 NQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGY 92
N+ ++ HV+ +DPE++DI+ E+KRQ+ + LI SENFTSK+VMD LGS M NKYSEGY
Sbjct: 21 NENILVDHVEKVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGY 80
Query: 93 PGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDR 152
PG RYYGGN+FID E LCQKRALE++ LDP WGVNVQPLSG+PAN Y+A++ +N R
Sbjct: 81 PGARYYGGNEFIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNGR 140
Query: 153 LMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPK 212
+MGLDLP GGHL+HG+ P+ K+S S++FQ++PY VD TG+IDYD L + + LFRPK
Sbjct: 141 IMGLDLPDGGHLTHGFFTPA-RKVSATSEFFQSLPYKVDPTTGLIDYDKLEQNAMLFRPK 199
Query: 213 VIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTH 272
I+AG S Y+R LDY+RF++IA GAYLMSDMAHISGLVAAG+ SPFEYSD+VTTTTH
Sbjct: 200 AIIAGVSCYARHLDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTH 259
Query: 273 KSLRGPRGAMIFYXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALK 332
KSLRGPRGA+IFY + LYDL+++IN +VFPG QGGPHNHTI+ +AVAL+
Sbjct: 260 KSLRGPRGALIFYRKGVRSTNAKGVDTLYDLEEKINSAVFPGLQGGPHNHTIAGIAVALR 319
Query: 333 QAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLL 392
Q + +F +Y V++NA+ E + K G+ L +GGTD HL+L++L +G++GAR E +L
Sbjct: 320 QCLSEDFVQYGEQVLKNAKTLAERMKKHGYALATGGTDNHLLLVDLRPIGVEGARAEHVL 379
Query: 393 ENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKS 452
+ +IA NKNT PGD SAL P G+R+GTPA+T+RGF Q+F +V +I V++A +
Sbjct: 380 DLAHIACNKNTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHEGVQIAKKYNA 439
Query: 453 QESPDAKDARSKLASFKELCKESDQVKQLADEVYQWVGEFPVPG 496
+ KD +S + + K+ V LA V ++ +F +PG
Sbjct: 440 EAGKTLKDFKSFTETNEPFKKD---VADLAKRVEEFSTKFEIPG 480
>At5g26780 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 532
Score = 512 bits (1318), Expect = e-145
Identities = 267/518 (51%), Positives = 356/518 (68%), Gaps = 32/518 (6%)
Query: 10 RAVLFSAKRSLASQANTGANASANQV-MVSKHVQDIDPEMYDILTKERKRQKHSITLIPS 68
R + S K+ ++ ++ G + + ++ + +IDPE+ DI+ E+ RQ LIPS
Sbjct: 6 RRLSSSVKKPISLLSSNGGSLRFMWIKQLNASLDEIDPEVADIIELEKARQWKGFELIPS 65
Query: 69 ENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQF---------IDMAESLCQKRALELY 119
ENFTS SVM +GS M NKYSEGYPG RYYGGN++ IDMAE+LCQKRALE +
Sbjct: 66 ENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYVVCILLTRYIDMAETLCQKRALEAF 125
Query: 120 NLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGGHLSHGYQLPSGTKISYI 179
LDP WGVNVQ LSG+PAN Y+A+++ ++R+M LDLPHGGHLSHGYQ + KIS +
Sbjct: 126 QLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMALDLPHGGHLSHGYQTDT-KKISAV 184
Query: 180 SKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYSRVLDYKRFKEIADACGA 239
S +F+TMPY +D TG IDYD L K++ LFRPK+IVAGASAY+R+ DY R +++ + A
Sbjct: 185 SIFFETMPYRLDENTGYIDYDQLEKSAVLFRPKLIVAGASAYARLYDYARIRKVCNKQKA 244
Query: 240 YLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAMIFYXXXXXXXXXXXXEV 299
+++DMAHISGLVAAGV SPFEY+D+VTTTTHKSLRGPRGAMIF+ EV
Sbjct: 245 VMLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGLKEINKQGKEV 304
Query: 300 LYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEYQAAVVENARIFGE---- 355
+YD + RIN +VFPG QGGPHNHTI+ LAVALKQA TPE+K YQ V+ N F E
Sbjct: 305 MYDYEDRINQAVFPGLQGGPHNHTITGLAVALKQARTPEYKAYQDQVLRNCSKFAELDIR 364
Query: 356 ------------ELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKNT 403
L+ KG++LVSGGTD HL+L+NL N GIDG+R+E +LE ++IAANKNT
Sbjct: 365 PTVIISYGLSMQTLLAKGYDLVSGGTDNHLVLVNLKNKGIDGSRVEKVLELVHIAANKNT 424
Query: 404 IPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDAKDA-- 461
+PGD SA+ P G+R+GTPA+T+RGF ++FA+VA Y D AVK+A+ IK++ K +
Sbjct: 425 VPGDVSAMVPGGIRMGTPALTSRGFIEEDFAKVAEYFDLAVKIALKIKAESQGIYKKSFG 484
Query: 462 ---RSKLASFKELCKESDQVKQLADEVYQWVGEFPVPG 496
+ +A+ + K ++ +L + V ++ +FP G
Sbjct: 485 TKLKDFVATMQSNEKLQSEMSKLREMVEEYAKQFPTIG 522
>At4g32520 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 462
Score = 494 bits (1273), Expect = e-140
Identities = 245/454 (53%), Positives = 318/454 (69%), Gaps = 10/454 (2%)
Query: 43 DIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQ 102
++DPE+ I+TKE+ RQ S+ LI SENFTS++VM+ +GS + NKYSEG PG+RYYGGN+
Sbjct: 18 EVDPEVRTIITKEKDRQFRSLELIASENFTSRAVMEAVGSCLTNKYSEGLPGKRYYGGNE 77
Query: 103 FIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGG 162
+ID E+LCQ RAL + LD WGVNVQPLSG+PAN Y+A++ +DR+MGLDLPHGG
Sbjct: 78 YIDQLETLCQNRALAAFRLDSTKWGVNVQPLSGSPANFAVYTAILSPHDRIMGLDLPHGG 137
Query: 163 HLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYS 222
HLSHG+ + + ++S S YF++MPY +D TGI+DYD L KT+ LFRPK+I+AGASAYS
Sbjct: 138 HLSHGF-MTAKRRVSGTSIYFESMPYRLDESTGIVDYDMLEKTATLFRPKLIIAGASAYS 196
Query: 223 RVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAM 282
R DY R ++IAD+ GA+LM DMAHISGLVAA V PFEY DIVTTTTHKSLRGPRG M
Sbjct: 197 RDFDYPRMRKIADSVGAFLMMDMAHISGLVAASVVADPFEYCDIVTTTTHKSLRGPRGGM 256
Query: 283 IFYXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEY 342
IF+ DL+ +N +VFPG QGGPHNHTI LAV LK A +PEFK Y
Sbjct: 257 IFFRKDPING--------VDLESAVNNAVFPGLQGGPHNHTIGGLAVCLKHAQSPEFKAY 308
Query: 343 QAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKN 402
Q VV N R LV+ GF+LVSGG+D HL+L++L +G+DGAR+E +L+ +I NKN
Sbjct: 309 QKRVVSNCRALANRLVELGFKLVSGGSDNHLVLVDLRPMGMDGARVEKILDMASITLNKN 368
Query: 403 TIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDAKDAR 462
++PGDKSAL P G+R+G+PAMTTRG ++F VA +I V++ + K
Sbjct: 369 SVPGDKSALVPGGIRIGSPAMTTRGLSEKDFVVVADFIKEGVEITMEAKKAAPGSKLQDF 428
Query: 463 SKLASFKELCKESDQVKQLADEVYQWVGEFPVPG 496
+K + E ++VK L + V + FP+PG
Sbjct: 429 NKFVTSPEF-PLKERVKSLKERVETFTSRFPIPG 461
>7290652 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 537
Score = 491 bits (1264), Expect = e-138
Identities = 237/466 (50%), Positives = 336/466 (71%), Gaps = 5/466 (1%)
Query: 32 ANQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEG 91
A+Q ++ + DPE+ +++ KE++RQ+ + +I SENFTS +V++ L S + NKYSEG
Sbjct: 72 ADQKLLQTPLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEG 131
Query: 92 YPGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETND 151
YPG+RYYGGN++ID E L Q+R EL+NLD + WGVNVQP SG+PANL Y+ V +D
Sbjct: 132 YPGKRYYGGNEYIDRIELLAQQRGRELFNLDDEKWGVNVQPYSGSPANLAVYTGVCRPHD 191
Query: 152 RLMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRP 211
R+MGLDLP GGHL+HG+ P+ KIS S +F++MPY V+ +TGIIDYD L++ +K FRP
Sbjct: 192 RIMGLDLPDGGHLTHGFFTPT-KKISATSIFFESMPYKVNPETGIIDYDKLAEAAKNFRP 250
Query: 212 KVIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTT 271
++I+AG S YSR+LDY RF++I D GAYLM+DMAH++G+VAAG+ SPFE++DIVTTTT
Sbjct: 251 QIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTT 310
Query: 272 HKSLRGPRGAMIFYXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVAL 331
HK+LRGPR +IF+ +VLYDL++RIN +VFP QGGPHN+ ++ +A A
Sbjct: 311 HKTLRGPRAGVIFFRKGVRSTKANGDKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAF 370
Query: 332 KQAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETL 391
KQA +PEFK YQ V++NA+ + L+ +G+++ +GGTD HL+L+++ G+ GA+ E +
Sbjct: 371 KQAKSPEFKAYQTQVLKNAKALCDGLISRGYQVATGGTDVHLVLVDVRKAGLTGAKAEYI 430
Query: 392 LENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAI-GI 450
LE + IA NKNT+PGDKSA+ PSG+R+GTPA+TTRG Q+ QV A+ID A+K+ +
Sbjct: 431 LEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVVAFIDAALKVGVQAA 490
Query: 451 KSQESPDAKDARSKLASFKELCKESDQVKQLADEVYQWVGEFPVPG 496
K SP D LA EL + D++++ V Q+ +FP+PG
Sbjct: 491 KLAGSPKITDYHKTLAENVELKAQVDEIRK---NVAQFSRKFPLPG 533
>Hs20070176 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 483
Score = 483 bits (1243), Expect = e-136
Identities = 249/470 (52%), Positives = 330/470 (69%), Gaps = 10/470 (2%)
Query: 31 SANQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSE 90
S++ M+++ ++D D E+Y+I+ KE RQ+ + LI SENF S++V++ LGS + NKYSE
Sbjct: 16 SSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSE 75
Query: 91 GYPGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETN 150
GYPG+RYYGG +FID E+LCQKRAL+ Y LDPQ WGVNVQP SG+PAN Y+A++E +
Sbjct: 76 GYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPH 135
Query: 151 DRLMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFR 210
R+MGLDLP GGHL+HG+ + KIS S +F++MPY V+ TG I+YD L + ++LF
Sbjct: 136 GRIMGLDLPDGGHLTHGF-MTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFH 194
Query: 211 PKVIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTT 270
PK+I+AG S YSR L+Y R ++IAD GAYLM+DMAHISGLVAAGV SPFE+ +VTTT
Sbjct: 195 PKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 254
Query: 271 THKSLRGPRGAMIFYXXXXXXXX-XXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAV 329
THK+LRG R MIFY E+LY+L+ IN +VFPG QGGPHNH I+ +AV
Sbjct: 255 THKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 314
Query: 330 ALKQAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLE 389
ALKQA T EFK YQ VV N R E L + G+++V+GG+D HLIL++L + G DG R E
Sbjct: 315 ALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 374
Query: 390 TLLENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIG 449
+LE +IA NKNT PGD+SAL PSGLR+GTPA+T+RG ++F +VA +I R ++L +
Sbjct: 375 KVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQ 434
Query: 450 IKSQESPDAKDARSKLASFKELC---KESDQVKQLADEVYQWVGEFPVPG 496
I+S R+ L FKE K V+ L +EV + FP+PG
Sbjct: 435 IQSDTG-----VRATLKEFKERLAGDKYQAAVQALREEVESFASFFPLPG 479
>Hs19923315 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 504
Score = 480 bits (1235), Expect = e-135
Identities = 247/498 (49%), Positives = 348/498 (69%), Gaps = 20/498 (4%)
Query: 7 RCSRAVLFS--AKRSLASQANTGANASANQVMVSKH-VQDIDPEMYDILTKERKRQKHSI 63
RC + V + A+ S A+Q TG AN+ + + D DPEM+++L +E+ RQ +
Sbjct: 15 RCGQLVRMAIRAQHSNAAQTQTG---EANRGWTGQESLSDSDPEMWELLQREKDRQCRGL 71
Query: 64 TLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQFIDMAESLCQKRALELYNLDP 123
LI SENF S++ ++ LGS + NKYSEGYPG+RYYGG + +D E LCQ+RALE ++LDP
Sbjct: 72 ELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDP 131
Query: 124 QLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGGHLSHGYQLPSGTKISYISKYF 183
WGVNVQP SG+PANL Y+A+++ +DR+MGLDLP GGHL+HGY + +IS S +F
Sbjct: 132 AQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGY-MSDVKRISATSIFF 190
Query: 184 QTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYSRVLDYKRFKEIADACGAYLMS 243
++MPY ++ +TG+IDY+ L+ T++LFRP++I+AG SAY+R++DY R +E+ D A+L++
Sbjct: 191 ESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLA 250
Query: 244 DMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAMIFYXXXXXXXX-XXXXEVLYD 302
DMAHISGLVAA V SPF+++DIVTTTTHK+LRG R +IFY E+ Y
Sbjct: 251 DMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYT 310
Query: 303 LDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEYQAAVVENARIFGEELVKKGF 362
+ RINF+VFP QGGPHNH I+A+AVALKQA TP F+EY V++NAR + L+++G+
Sbjct: 311 FEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGY 370
Query: 363 ELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKNTIPGDKSALFPSGLRVGTPA 422
LVSGGTD HL+L++L G+DGAR E +LE ++I ANKNT PGD+SA+ P GLR+G PA
Sbjct: 371 SLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPA 430
Query: 423 MTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDAKDARSKLASFKE-LCKESDQVKQL 481
+T+R F +F +V +ID V + + +KS+ +KL FK L K+S+ ++L
Sbjct: 431 LTSRQFREDDFRRVVDFIDEGVNIGLEVKSK--------TAKLQDFKSFLLKDSETSQRL 482
Query: 482 AD---EVYQWVGEFPVPG 496
A+ V Q+ FP+PG
Sbjct: 483 ANLRQRVEQFARAFPMPG 500
>At4g13930 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 471
Score = 455 bits (1171), Expect = e-128
Identities = 233/456 (51%), Positives = 305/456 (66%), Gaps = 8/456 (1%)
Query: 44 IDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQF 103
+DPE++D++ KE++RQ I LI SENFTS +V++ LGS + NKYSEG PG RYYGGN+F
Sbjct: 15 VDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGIPGNRYYGGNEF 74
Query: 104 IDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGGH 163
ID E+LC+ RALE ++ DP WGVNVQP SG+PAN AY+A+++ +DR+MGLDLP GGH
Sbjct: 75 IDEIENLCRSRALEAFHCDPAAWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGH 134
Query: 164 LSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYSR 223
L+HGY G KIS S YF+++PY V+ TG IDYD L + + FRPK+++ G SAY R
Sbjct: 135 LTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKALDFRPKLLICGGSAYPR 194
Query: 224 VLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAMI 283
DY RF+ IAD GA L+ DMAHISGLVAA +PFEY D+VTTTTHKSLRGPR MI
Sbjct: 195 DWDYARFRAIADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMI 254
Query: 284 FYXXXXXXXXXXXXE-VLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEY 342
FY E +YD + +INF+VFP QGGPHNH I ALAVALKQA TP FK Y
Sbjct: 255 FYRKGPKPPKKGQPEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGFKVY 314
Query: 343 QAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKN 402
V NA G L+ KG+++V+ GT+ HL+L +L LG+ G ++E L + +I NKN
Sbjct: 315 AKQVKANAVALGNYLMSKGYQIVTNGTENHLVLWDLRPLGLTGNKVEKLCDLCSITLNKN 374
Query: 403 TIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDAKDAR 462
+ GD SAL P G+R+G PAMT+RG ++F Q+ ++ RAV L + I+ KD
Sbjct: 375 AVFGDSSALAPGGVRIGAPAMTSRGLVEKDFEQIGEFLSRAVTLTLDIQKTYGKLLKDFN 434
Query: 463 SKLASFKELCKESDQVKQLADEVYQWVGEFPVPGEL 498
L + K+L QL +V ++ + +PG L
Sbjct: 435 KGLVNNKDL-------DQLKADVEKFSASYEMPGFL 463
>At4g13890 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 470
Score = 439 bits (1130), Expect = e-123
Identities = 224/458 (48%), Positives = 300/458 (64%), Gaps = 8/458 (1%)
Query: 40 HVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYG 99
H+ +DPE+YD++ KE+ RQ I LI +ENFTS +VM+ LGS + NKYSEG PG RYYG
Sbjct: 11 HLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYG 70
Query: 100 GNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLP 159
G +FID ESLC+ R+LE ++ +P+ WGVNVQP SG+PAN AY+A+++ +DR+MGLDLP
Sbjct: 71 GTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLP 130
Query: 160 HGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGAS 219
GGH++HGY G IS S YF+ +PY VDS+TG IDYD L + + FRPK+I+ G +
Sbjct: 131 SGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGT 190
Query: 220 AYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPR 279
+Y R DY RF+ +AD GA+L+ DMAH S LVAA PFEY D+VTT+THKSLRGPR
Sbjct: 191 SYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPR 250
Query: 280 GAMIFYXXXXXXXXXXXXE-VLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPE 338
MIFY E +YD D +IN +VFP Q GPHN+ I ALAVALKQ P
Sbjct: 251 AGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPS 310
Query: 339 FKEYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIA 398
FK Y V NA L+ KG+ LV+ GTD HLIL +L LG+ G ++E + E I
Sbjct: 311 FKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYIT 370
Query: 399 ANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDA 458
N+N + GD S L P G+R+GTPAMT+RG ++F ++ ++ RAV + + I+ Q
Sbjct: 371 LNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVM 430
Query: 459 KDARSKLASFKELCKESDQVKQLADEVYQWVGEFPVPG 496
KD L + KE+ D++K +V ++ +F +PG
Sbjct: 431 KDFNKGLVNNKEI----DEIKA---DVEEFTYDFDMPG 461
>At1g22020 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 599
Score = 411 bits (1057), Expect = e-114
Identities = 213/489 (43%), Positives = 303/489 (61%), Gaps = 15/489 (3%)
Query: 2 LSRSARCSRAVLFSAKRSLASQANTGANASANQVMVSKHVQDIDPEMYDILTKERKRQKH 61
L+ S+ C R V+ S S + N S +++ DPE+++ + KE++RQ
Sbjct: 112 LASSSPCKRFVVDSGIESRRAVVRAWGNQS---------IEEADPEIHEFMEKEKQRQFR 162
Query: 62 SITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQFIDMAESLCQKRALELYNL 121
I LI SENF ++VM+ LGS + NKYSEG PG RYY GNQ+ID E LCQ+RAL + L
Sbjct: 163 GIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYYTGNQYIDQIEILCQERALAAFGL 222
Query: 122 DPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGGHLSHGYQLPSGTKISYISK 181
+ + WGVNVQP S AN ++ ++ +R+MGLD P GGH+SHGY P G K+S S
Sbjct: 223 NHEKWGVNVQPYSCTSANFAVFTGLLMPGERIMGLDSPSGGHMSHGYYTPGGKKVSGASI 282
Query: 182 YFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYSRVLDYKRFKEIADACGAYL 241
+F++ PY VD +TG IDYD L + + +RPK+++ G S+Y R ++ RF+ IAD CGA L
Sbjct: 283 FFESFPYKVDPRTGYIDYDKLEEKALDYRPKILICGGSSYPRDWEFPRFRHIADKCGAVL 342
Query: 242 MSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAMIFY------XXXXXXXXXX 295
M DMA ISGLVAA + +PF+Y DIVT+TTHKSLRGPRG +IFY
Sbjct: 343 MFDMAQISGLVAAKESPNPFDYCDIVTSTTHKSLRGPRGGIIFYKRGLKPKKQSINLNHC 402
Query: 296 XXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEYQAAVVENARIFGE 355
+ YD +++INFSVFP QGGPHN+ I+ALA+ALKQAA+PE+K Y V +NA+
Sbjct: 403 ESNIQYDFEEKINFSVFPSLQGGPHNNHIAALAIALKQAASPEYKLYMRQVKKNAKALAS 462
Query: 356 ELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKNTIPGDKSALFPSG 415
L+ + +L++GGTD HL+L +L+ LG+ G E + E +I NK I + + P G
Sbjct: 463 ALISRKCKLITGGTDNHLLLWDLTPLGLTGKVYEKVCEMCHITVNKVAIFSENGVISPGG 522
Query: 416 LRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDAKDARSKLASFKELCKES 475
+R+G+PAMT+RG EF +A ++ RA ++A + + K+ + KE+
Sbjct: 523 VRIGSPAMTSRGCLEPEFETMADFLYRAAQIASAAQREHGKLQKEPLKSIYHCKEIADLR 582
Query: 476 DQVKQLADE 484
+QV+ A +
Sbjct: 583 NQVEAFATQ 591
>ECU01g1420 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 460
Score = 410 bits (1055), Expect = e-114
Identities = 211/402 (52%), Positives = 273/402 (67%), Gaps = 7/402 (1%)
Query: 45 DPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQFI 104
DPE++ ++ E +RQK +I LI SEN+ +S M+ GS + NKYSEG GERYYGG ++
Sbjct: 18 DPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVLTNKYSEGRVGERYYGGTHWV 77
Query: 105 DMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGGHL 164
D E LCQKRALEL+ LDP +WGVNVQP SG+PAN Y+AV+ R+MGLDLP GGHL
Sbjct: 78 DRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYTAVVPPGGRIMGLDLPSGGHL 137
Query: 165 SHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYSRV 224
+HGY+ + KIS S YF + PY V S G+IDY+ L KT F P +++ G SAYSR
Sbjct: 138 THGYKTKT-RKISASSVYFDSRPYTVGS-NGLIDYEGLEKTFTDFLPHILICGYSAYSRD 195
Query: 225 LDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAMIF 284
+DYKR + IA GA+L +D++HIS LVA+G+ SPFE+ DIV TTT K LRGPRGA+IF
Sbjct: 196 IDYKRLQSIAGRNGAFLFADISHISPLVASGLMNSPFEHCDIVMTTTQKGLRGPRGALIF 255
Query: 285 YXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEYQA 344
Y DLD RINF+VFP QGGPHNHTI+ +A AL A TPEF EY
Sbjct: 256 YRRAVTKNGET-----VDLDARINFAVFPMLQGGPHNHTIAGIASALLHAGTPEFAEYTR 310
Query: 345 AVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKNTI 404
VVEN+R L G ++++GGTD H++L++L + G+DGA +E + + + I+ N+N I
Sbjct: 311 RVVENSRELCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDGAAVEHMCDALGISLNRNAI 370
Query: 405 PGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKL 446
G+ S L PSG+RVGT A+T RGFGP+E +V I VKL
Sbjct: 371 VGNSSPLSPSGIRVGTYAVTARGFGPEEMREVGDIIGGVVKL 412
>ECU01g0190 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 460
Score = 410 bits (1055), Expect = e-114
Identities = 211/402 (52%), Positives = 273/402 (67%), Gaps = 7/402 (1%)
Query: 45 DPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQFI 104
DPE++ ++ E +RQK +I LI SEN+ +S M+ GS + NKYSEG GERYYGG ++
Sbjct: 18 DPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVLTNKYSEGRVGERYYGGTHWV 77
Query: 105 DMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGGHL 164
D E LCQKRALEL+ LDP +WGVNVQP SG+PAN Y+AV+ R+MGLDLP GGHL
Sbjct: 78 DRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYTAVVPPGGRIMGLDLPSGGHL 137
Query: 165 SHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYSRV 224
+HGY+ + KIS S YF + PY V S G+IDY+ L KT F P +++ G SAYSR
Sbjct: 138 THGYKTKT-RKISASSVYFDSRPYTVGS-NGLIDYEGLEKTFTDFLPHILICGYSAYSRD 195
Query: 225 LDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAMIF 284
+DYKR + IA GA+L +D++HIS LVA+G+ SPFE+ DIV TTT K LRGPRGA+IF
Sbjct: 196 IDYKRLQSIAGRNGAFLFADISHISPLVASGLMNSPFEHCDIVMTTTQKGLRGPRGALIF 255
Query: 285 YXXXXXXXXXXXXEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKEYQA 344
Y DLD RINF+VFP QGGPHNHTI+ +A AL A TPEF EY
Sbjct: 256 YRRAVTKNGET-----VDLDARINFAVFPMLQGGPHNHTIAGIASALLHAGTPEFAEYTR 310
Query: 345 AVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANKNTI 404
VVEN+R L G ++++GGTD H++L++L + G+DGA +E + + + I+ N+N I
Sbjct: 311 RVVENSRELCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDGAAVEHMCDALGISLNRNAI 370
Query: 405 PGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKL 446
G+ S L PSG+RVGT A+T RGFGP+E +V I VKL
Sbjct: 371 VGNSSPLSPSGIRVGTYAVTARGFGPEEMREVGDIIGGVVKL 412
>At1g36370 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 578
Score = 405 bits (1041), Expect = e-113
Identities = 205/472 (43%), Positives = 296/472 (62%), Gaps = 6/472 (1%)
Query: 17 KRSLASQANTGANASANQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSV 76
KRS ++ + +A + + + DP++++++ KE++RQ I LI SENF ++V
Sbjct: 94 KRSSIGDSDLESRRAAVRAWGDQPIHLADPDIHELMEKEKQRQVRGIELIASENFVCRAV 153
Query: 77 MDLLGSEMQNKYSEGYPGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGA 136
M+ LGS + NKYSEG PG RYY GNQ+ID E+LC +RAL + L+ WGVNVQP S
Sbjct: 154 MEALGSHLTNKYSEGMPGARYYTGNQYIDQIENLCIERALTAFGLESDKWGVNVQPYSCT 213
Query: 137 PANLYAYSAVMETNDRLMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGI 196
AN Y+ ++ +R+MGLD P GGH+SHGY P G KIS S +F++ PY V+ QTG
Sbjct: 214 SANFAVYTGLLLPGERIMGLDSPSGGHMSHGYCTPGGKKISAASIFFESFPYKVNPQTGY 273
Query: 197 IDYDFLSKTSKLFRPKVIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGV 256
IDYD L + +RPK+++ G S+Y R D+ R ++IAD CGA LM DMAHISGLVA
Sbjct: 274 IDYDKLEDKALDYRPKILICGGSSYPRDWDFARVRQIADKCGAVLMCDMAHISGLVATKE 333
Query: 257 TRSPFEYSDIVTTTTHKSLRGPRGAMIFY------XXXXXXXXXXXXEVLYDLDKRINFS 310
+PF++ DIVT+TTHK LRGPRG +IFY YDL+++INF+
Sbjct: 334 CSNPFDHCDIVTSTTHKGLRGPRGGIIFYRRGPKIRKQGHHSSHCDTSTHYDLEEKINFA 393
Query: 311 VFPGHQGGPHNHTISALAVALKQAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTD 370
VFP QGGPHN+ I+ALA+ALKQ ATPE+K Y + +NA+ L+++ LV+GGTD
Sbjct: 394 VFPSLQGGPHNNHIAALAIALKQVATPEYKAYIQQMKKNAQALAAALLRRKCRLVTGGTD 453
Query: 371 THLILINLSNLGIDGARLETLLENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGP 430
HL+L +L+ +G+ G E + E +I NK I GD + P G+R+GTPAMTTRG
Sbjct: 454 NHLLLWDLTPMGLTGKVYEKVCEMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIE 513
Query: 431 QEFAQVAAYIDRAVKLAIGIKSQESPDAKDARSKLASFKELCKESDQVKQLA 482
+F +A ++ +A ++ ++ + K+ L + K++ + ++V+ A
Sbjct: 514 SDFETMADFLIKAAQITSALQREHGKSHKEFVKSLCTNKDIAELRNRVEAFA 565
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,434,488
Number of Sequences: 60738
Number of extensions: 1206301
Number of successful extensions: 2986
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2937
Number of HSP's gapped (non-prelim): 17
length of query: 498
length of database: 30,389,216
effective HSP length: 111
effective length of query: 387
effective length of database: 23,647,298
effective search space: 9151504326
effective search space used: 9151504326
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)