ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0359 good S KOG2911 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0359 124602 123280 -441
(441 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL049w [S] KOG2911 Uncharacterized conserved protein 181 2e-45
SPBC1604.18c [S] KOG2911 Uncharacterized conserved protein 91 3e-18
CE03710 [S] KOG2911 Uncharacterized conserved protein 80 6e-15
Hs14748162 [S] KOG2911 Uncharacterized conserved protein 58 2e-08
7291437 [R] KOG2910 Uncharacterized conserved protein predicted ... 55 2e-07
CE22731 [R] KOG2910 Uncharacterized conserved protein predicted ... 54 6e-07
>YJL049w [S] KOG2911 Uncharacterized conserved protein
Length = 450
Score = 181 bits (459), Expect = 2e-45
Identities = 115/427 (26%), Positives = 213/427 (48%), Gaps = 10/427 (2%)
Query: 2 LPESRLRSLYSDFRGLKLLNIDGYEANIRQWKEYLIKEFWSD---LIIINAADLLSELSN 58
LPESRL SLY DFR LK LN DGYEANI W+++ ++++ S+ +I L EL++
Sbjct: 5 LPESRLPSLYRDFRPLKDLNPDGYEANISTWRDFFLQQYISNSNRIIFTIGTRTLQELTH 64
Query: 59 SQYGAPKSIDVVLDEMVKEGTLVSLNEYH---KRNQNIVISMMSWAISKTILDLSWKSRK 115
YG PKSID+ +D +V EG L+ + ++ N W S +KSRK
Sbjct: 65 EVYGVPKSIDIAIDVLVNEGNLIPMELFNLGGMYTDNSRKGFWKWVRSWKESTNMYKSRK 124
Query: 116 NETAMYLKPVKYVNIAWLKRNDEVLQDLLKNNIKESAHKATDYVFTKGHFYKASGIDSIV 175
+ET YL+ K++ A L++ + +LLK ++ A TD VFT+ F + S
Sbjct: 125 DETNFYLREDKFIIKANLEKEYQRFHELLKRSVFMEASSITDLVFTRNEFVTTESLQSFF 184
Query: 176 KDWD--SYGIILDYLCDKNQIIVGSENIVKIISPLLSASPQVASKEVSEEDICVANINEY 233
+D + + L ++ + IIV +N++K+I+ + SK ++E D+ +A++
Sbjct: 185 STYDEETKNVFLHFIENYKHIIVSKDNVIKVIAAEVEDITSRFSKGITENDLRIASVKVG 244
Query: 234 VFTAETEIKSAQKVLDLTTKRLTSAISSGLSQEIKRTLLRLKKRSEKNLEQAYTSLESLR 293
+ +I +K ++ + +L + L + I+ + + SEK+L + +L
Sbjct: 245 IININKQITRLRKEINESNIKLRGPEFNELPKRIRIEYKQARLLSEKHLSRLLKFQNNLA 304
Query: 294 KLQDEISNASQNVVMINLLKQGSTALKAINSQLLDEDSISNILDDFQENTEKQDRIHNLL 353
+++ +I ++ N V+I L + + +K+IN + + + ++LD+ +E ++ + +++LL
Sbjct: 305 QVRTQIDTSATNAVLIQTLSESNEVIKSINGYIGSTEKVEDLLDEIKEGHDRTEEVNDLL 364
Query: 354 VGESVSDNDAXXXXXXXXXXXXXXXXXXXXXXXXXXXQKSAAPLESGSTEDLIKKLGSLR 413
+ D Q P ES S+EDL+K+L +L+
Sbjct: 365 AHYN-KGQDEEAEEEIERELEQLELDEKNNNKEENKNQDLHEPKES-SSEDLLKRLNNLK 422
Query: 414 VSSRDSP 420
+++ + P
Sbjct: 423 INTNEGP 429
>SPBC1604.18c [S] KOG2911 Uncharacterized conserved protein
Length = 449
Score = 91.3 bits (225), Expect = 3e-18
Identities = 86/364 (23%), Positives = 165/364 (44%), Gaps = 29/364 (7%)
Query: 4 ESRLRSLYSDFRGLKLLNIDGYEANIRQWKEYLIKEFWSD-----LIIINAADLLSELSN 58
++RL+SLYSDF L + N +G+ AN+ W+E + WS +I++ S S+
Sbjct: 21 KTRLKSLYSDFTSLFIKNPEGFLANVNTWREAIETSAWSGKLNSRIILVFDETFESAFSS 80
Query: 59 SQYGAPKSIDVVLDEMVKEGTLVS----LNEYHKRN-----QNIVISMMSWAISKTILDL 109
G P S+ V +++G + LN+ K N + S++ W+ K L
Sbjct: 81 PALGRPLSLGAVAAYWIQQGVWLRKQDFLNDCKKGNLVREDGFSIFSILRWSFQK----L 136
Query: 110 SWKSRKNETAMYLKPV-KYVNIAWLKRNDEVLQDLLKNNIKESAHKATDYVFTKGHFYKA 168
++++ + P +YV +++N E L L+ N T ++T F
Sbjct: 137 GFQNQASSILSNRSPSGQYV----IRKNIEKLACLVHNEAMRRCSSYTSAIYTWDFFQDT 192
Query: 169 SGI---DSIVKDWDSYGIILDYLCDKNQIIVGSENIVKIISPLLSASPQVASKEVSEEDI 225
G + + D +L+++C + +++ I+K + P Q+AS + S D
Sbjct: 193 FGSLYWEEGKLNKDEMECLLNWMCYQKHVLIFDSKIIKFL-PNSQIDAQLASIDKS-IDG 250
Query: 226 CVANINEYVFTAETEIKSAQKVLDLTTKRLTSAISSGLSQEIKRTLLRLKKRSEKNLEQA 285
VA++ + + + + L+ ++ L A+ G + I T LR KK K+LE+
Sbjct: 251 SVADLIQARASIAQRSEFLNEELEQLSQVLNQAVKKG-EKTIAITYLRRKKILSKDLERK 309
Query: 286 YTSLESLRKLQDEISNASQNVVMINLLKQGSTALKAINSQLLDEDSISNILDDFQENTEK 345
+S L + I NA N +++ + GS AL AI +Q+ + + ++L++ + +
Sbjct: 310 VSSRLQLDTIISNIDNAVDNKILLIAMSSGSEALDAILAQMGGTEKVEDVLENVNDTLAR 369
Query: 346 QDRI 349
+ I
Sbjct: 370 SEEI 373
>CE03710 [S] KOG2911 Uncharacterized conserved protein
Length = 411
Score = 80.1 bits (196), Expect = 6e-15
Identities = 80/333 (24%), Positives = 150/333 (45%), Gaps = 29/333 (8%)
Query: 40 FWSDLII------INAADLLSELSNS---QYGAPKSIDVVLDEMVKEGTLVSLNEYHKRN 90
FW+D I NA L EL P S+DV+LD + K+G ++++ E+ R+
Sbjct: 38 FWTDAIYGSCIGEKNATFNLLELKKRFRRNDRVPASLDVILDHLKKKGDVITIGEWRDRH 97
Query: 91 QNIVISMMSWAISKTILDLSWKSRKNETAMYLKPVKYVNIAWLKRNDEVLQDLLKNNIKE 150
S + W SKT + S +E ++L +K K E+L D+ ++
Sbjct: 98 S----SWVGWGFSKTKGWMFGASSDSEQLLHLPTIK-------KLGQEIL-DIYNEELRS 145
Query: 151 SAHKATDYVFTKGHFYKASGIDSIVKDWDSYGIILDYLCDKNQIIVGS-ENIVKIISPLL 209
+ V F +AS I S ++ +D I+L++L D ++ VG+ N K++
Sbjct: 146 EIDCTGEVVTYNEMFDRASNIISKIETFD---IVLEHLNDIGELTVGTTRNGEKVLKFKD 202
Query: 210 SASPQVASKEVSEEDICVANINEYVFTAETEIKSAQKVLDLTTKRLTSAISSGLSQEIKR 269
+ S + +E D V +I + + + EI+ ++ + ++ + + +G + +
Sbjct: 203 NGSEDPV--KFTEADASVVDIRKAMNKLDREIQQLEQKVKKYDEQCRACLRTG-DKGRAQ 259
Query: 270 TLLRLKKRSEKNLEQAYTSLESLRKLQDEISNASQNVVMINLLKQGSTALKA-INSQLLD 328
LR +KR+EK++ + L + +IS+A N ++ K G+ A KA + Q L
Sbjct: 260 NFLRQRKRAEKDIADKDVQYQKLLTMLHQISSAKNNKDVLQAYKSGTAAFKATLARQGLS 319
Query: 329 EDSISNILDDFQENTEKQDRIHNLLVGESVSDN 361
D I +DD + ++ I + V+ N
Sbjct: 320 PDKIHETMDDVVNSMDEYKEIEEAISSPFVNAN 352
>Hs14748162 [S] KOG2911 Uncharacterized conserved protein
Length = 453
Score = 58.2 bits (139), Expect = 2e-08
Identities = 68/362 (18%), Positives = 153/362 (41%), Gaps = 32/362 (8%)
Query: 4 ESRLRSLYSDFRGLKLLNIDGYEANIRQWKEYLIKEFWSDLIIINAADLLSELSNSQYGA 63
E R+ L+S F+ + +N +++ + W ++ ++ L E +
Sbjct: 28 EERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQGVVRLRLRDLQEAFQRKGSV 87
Query: 64 PKSIDVVLDEMVKEGTLVSLNEYHKRNQNIVISMMSWAISKTILDLSWKSRKNETAMYLK 123
P + VL ++++ G L +++ ++ S +SW + LK
Sbjct: 88 PLGLATVLQDLLRRGELQRESDFMA---SVDSSWISWGVG---------------VFLLK 129
Query: 124 PVKYVNIAWLKRN----DEVLQ--DLLKNNIKESAHKATDYVFTKGHFYKASGIDSIVK- 176
P+K+ L N +EVL +LLK +E + + S + ++
Sbjct: 130 PLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCAN 189
Query: 177 ---DWDSYGIILDYLCDKNQIIVGSENIVKIISPLLSASPQVASKEVSEEDICVANINEY 233
D ++ ++L L + ++ V +N KI+ + P+ V++ D+ V + +
Sbjct: 190 SCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVK--FARGPRAKVSPVNDVDVGVYQLMQS 247
Query: 234 VFTAETEIKSAQKVLDLTTKRLTSAISSGLSQEIKRTLLRLKKRSEKNLEQAYTSLESLR 293
+++S + + + A +G Q R+L + K+R+EK +E + L++++
Sbjct: 248 EQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSL-KAKQRTEKRIEALHAKLDTVQ 306
Query: 294 KLQDEISNASQNVVMINLLKQGSTALKAINSQLLDEDSISNILDDFQENTEKQDRIHNLL 353
+ D I + + ++ N + G ALK ++ + + + +++D QE + QD + L
Sbjct: 307 GILDRIYASQTDQMVFNAYQAGVGALK-LSMKDVTVEKAESLVDQIQELCDTQDEVSQTL 365
Query: 354 VG 355
G
Sbjct: 366 AG 367
>7291437 [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 212
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 212 SPQVASKEVSEEDICVANINEYVFTAETEIKSAQKVLD--LTTKRLTS--AISSGLSQEI 267
S + A ++++D V + + +K QK ++ L RL + + G
Sbjct: 9 SKKTAPSRITDQDKAVLQLKQQ----RDRLKQYQKRIETQLENDRLLARKCLQQGRKDRA 64
Query: 268 KRTLLRLKKRSEKNLEQAYTSLESLRKLQDEISNASQNVVMINLLKQGSTALKAINSQLL 327
K LLR KK E L A LE+L KL +I A + +++ LK G+ ALK ++ ++L
Sbjct: 65 K-LLLRKKKYQESLLTNADKQLENLEKLAADIEFAQVEMKVLDGLKAGNAALKKVH-EML 122
Query: 328 DEDSISNILDDFQENTEKQDRIHNLL 353
D D + I+D+ +E EKQ I +L
Sbjct: 123 DIDEVERIMDETREGIEKQQEIDAIL 148
>CE22731 [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 208
Score = 53.5 bits (127), Expect = 6e-07
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 217 SKEVSEEDICVANINEYVFTAETEIKSAQKVLDLTTKRLTSAISSGLSQEIKRTLLRLKK 276
S VS++D + + + IK + L+ + I G R LL LKK
Sbjct: 14 SAPVSDQDNAILALKTQRDKMKQMIKRKENCLEKERQLAKQLIKDGRKD---RALLLLKK 70
Query: 277 R--SEKNLEQAYTSLESLRKLQDEISNASQNVVMINLLKQGSTALKAINSQLLDEDSISN 334
+ EK ++Q L + ++ +++ A + + L+QG+ ALK +N QL D D I
Sbjct: 71 KRYQEKIIDQTLNHLSKIEQMVNDLEFAEVQQRVTDGLRQGNEALKKMN-QLFDIDEIDR 129
Query: 335 ILDDFQENTEKQDRIHNLLVGE 356
I+++ +E E Q+ I N+L G+
Sbjct: 130 IMEETKEAAEYQEEISNMLSGQ 151
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.130 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,611,098
Number of Sequences: 60738
Number of extensions: 832786
Number of successful extensions: 2726
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2719
Number of HSP's gapped (non-prelim): 6
length of query: 441
length of database: 30,389,216
effective HSP length: 109
effective length of query: 332
effective length of database: 23,768,774
effective search space: 7891232968
effective search space used: 7891232968
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)