ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0397 check: MH D KOG0590 Cell cycle control, cell division, chromosome partitioning Checkpoint kinase and related serine/threonine protein kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0397 135424 136299 292
(292 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL025c [D] KOG0590 Checkpoint kinase and related serine/threoni... 110 2e-24
SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/thr... 100 2e-21
SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/thr... 100 2e-21
YNL183c [D] KOG0590 Checkpoint kinase and related serine/threoni... 100 3e-21
7299437 [R] KOG0586 Serine/threonine protein kinase 99 7e-21
7299438 [R] KOG0586 Serine/threonine protein kinase 94 2e-19
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 93 4e-19
YDL214c [D] KOG0590 Checkpoint kinase and related serine/threoni... 92 1e-18
YKL101w [D] KOG0588 Serine/threonine protein kinase 91 2e-18
CE27768 [R] KOG0586 Serine/threonine protein kinase 90 4e-18
CE23838 [R] KOG0586 Serine/threonine protein kinase 90 4e-18
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 90 4e-18
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 6e-18
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 6e-18
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 6e-18
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 89 1e-17
YOR267c [D] KOG0590 Checkpoint kinase and related serine/threoni... 88 1e-17
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 87 2e-17
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 86 6e-17
CE00847 [T] KOG0583 Serine/threonine protein kinase 86 6e-17
YDR122w [T] KOG0583 Serine/threonine protein kinase 86 8e-17
YCL024w [T] KOG0583 Serine/threonine protein kinase 86 8e-17
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 86 8e-17
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 86 8e-17
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 86 8e-17
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 86 8e-17
7302464 [R] KOG0586 Serine/threonine protein kinase 85 1e-16
At5g39440 [T] KOG0583 Serine/threonine protein kinase 85 1e-16
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 84 2e-16
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 2e-16
YDR477w [T] KOG0583 Serine/threonine protein kinase 84 2e-16
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 84 2e-16
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 84 3e-16
CE28643 [T] KOG0583 Serine/threonine protein kinase 83 4e-16
CE07458 [T] KOG0583 Serine/threonine protein kinase 83 4e-16
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 83 4e-16
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 83 5e-16
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 82 7e-16
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 82 7e-16
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 82 9e-16
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 82 1e-15
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 82 1e-15
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 82 1e-15
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 82 1e-15
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 81 2e-15
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 80 3e-15
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 3e-15
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 80 3e-15
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 80 3e-15
At3g29160 [T] KOG0583 Serine/threonine protein kinase 80 3e-15
YPL150w [T] KOG0583 Serine/threonine protein kinase 80 5e-15
YLR096w [T] KOG0583 Serine/threonine protein kinase 80 5e-15
YDR507c [D] KOG0588 Serine/threonine protein kinase 80 5e-15
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 80 5e-15
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 80 5e-15
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 79 6e-15
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 79 6e-15
At4g24400 [T] KOG0583 Serine/threonine protein kinase 79 6e-15
7290249 [R] KOG0586 Serine/threonine protein kinase 79 6e-15
CE28479 [T] KOG0583 Serine/threonine protein kinase 79 8e-15
At5g01820 [T] KOG0583 Serine/threonine protein kinase 79 8e-15
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 79 8e-15
CE16081 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
At3g01090 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 78 1e-14
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 78 1e-14
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 78 1e-14
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 78 1e-14
At5g45810 [T] KOG0583 Serine/threonine protein kinase 78 1e-14
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 78 1e-14
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 78 2e-14
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 78 2e-14
CE28218 [D] KOG0588 Serine/threonine protein kinase 78 2e-14
At2g34180 [T] KOG0583 Serine/threonine protein kinase 78 2e-14
7294217 [D] KOG0588 Serine/threonine protein kinase 78 2e-14
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 77 2e-14
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 2e-14
Hs19923134 [T] KOG4250 TANK binding protein kinase TBK1 77 3e-14
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 77 3e-14
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 77 4e-14
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 77 4e-14
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 77 4e-14
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 77 4e-14
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 77 4e-14
7290150 [T] KOG0583 Serine/threonine protein kinase 77 4e-14
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 76 5e-14
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-14
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 5e-14
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 76 5e-14
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 76 7e-14
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 76 7e-14
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 76 7e-14
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 76 7e-14
At2g30360 [T] KOG0583 Serine/threonine protein kinase 76 7e-14
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 75 8e-14
CE15235 [R] KOG0589 Serine/threonine protein kinase 75 8e-14
At5g35410 [T] KOG0583 Serine/threonine protein kinase 75 8e-14
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 75 1e-13
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 75 1e-13
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 75 1e-13
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 1e-13
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 75 1e-13
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 75 1e-13
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 1e-13
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 1e-13
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 75 1e-13
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 75 1e-13
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 75 1e-13
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 75 1e-13
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 75 1e-13
CE06686 [T] KOG0660 Mitogen-activated protein kinase 75 1e-13
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 75 1e-13
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 74 2e-13
At4g14580 [T] KOG0583 Serine/threonine protein kinase 74 2e-13
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 74 2e-13
7302570 [R] KOG0586 Serine/threonine protein kinase 74 2e-13
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 74 2e-13
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 74 2e-13
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 74 2e-13
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 74 2e-13
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 2e-13
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 74 2e-13
At1g29230 [T] KOG0583 Serine/threonine protein kinase 74 2e-13
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 74 2e-13
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 74 3e-13
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 74 3e-13
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 74 3e-13
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 74 3e-13
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 74 3e-13
CE17343 [T] KOG0583 Serine/threonine protein kinase 74 3e-13
At5g58380 [T] KOG0583 Serine/threonine protein kinase 74 3e-13
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 3e-13
At3g51630 [R] KOG0584 Serine/threonine protein kinase 74 3e-13
At2g26980 [T] KOG0583 Serine/threonine protein kinase 74 3e-13
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 74 3e-13
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 74 3e-13
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 73 4e-13
CE17284 [T] KOG0583 Serine/threonine protein kinase 73 4e-13
CE03080 [R] KOG0584 Serine/threonine protein kinase 73 4e-13
At5g57630 [T] KOG0583 Serine/threonine protein kinase 73 4e-13
At5g07070 [T] KOG0583 Serine/threonine protein kinase 73 4e-13
At2g30040 [T] KOG0198 MEKK and related serine/threonine protein ... 73 4e-13
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 73 6e-13
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 73 6e-13
At4g18700 [T] KOG0583 Serine/threonine protein kinase 73 6e-13
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 73 6e-13
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 72 7e-13
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 72 7e-13
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 72 7e-13
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 72 7e-13
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 72 7e-13
At5g58350 [R] KOG0584 Serine/threonine protein kinase 72 7e-13
At5g25110 [T] KOG0583 Serine/threonine protein kinase 72 7e-13
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 72 7e-13
At2g23030 [T] KOG0583 Serine/threonine protein kinase 72 7e-13
At1g78290 [T] KOG0583 Serine/threonine protein kinase 72 7e-13
7300413 [T] KOG0583 Serine/threonine protein kinase 72 7e-13
7298087 [T] KOG0660 Mitogen-activated protein kinase 72 7e-13
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 72 9e-13
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 72 9e-13
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 72 9e-13
CE27410 [T] KOG0583 Serine/threonine protein kinase 72 9e-13
CE24971 [T] KOG0660 Mitogen-activated protein kinase 72 9e-13
CE08727 [G] KOG0658 Glycogen synthase kinase-3 72 9e-13
CE01583 [T] KOG0660 Mitogen-activated protein kinase 72 9e-13
At5g66880 [T] KOG0583 Serine/threonine protein kinase 72 9e-13
7302050 [T] KOG0986 G protein-coupled receptor kinase 72 9e-13
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 72 1e-12
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 72 1e-12
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 72 1e-12
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
At1g30270 [T] KOG0583 Serine/threonine protein kinase 72 1e-12
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 72 1e-12
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 72 1e-12
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 71 2e-12
YKL116c [R] KOG0586 Serine/threonine protein kinase 71 2e-12
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 71 2e-12
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 71 2e-12
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 71 2e-12
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-12
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-12
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 71 2e-12
CE23001 [R] KOG0589 Serine/threonine protein kinase 71 2e-12
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 71 2e-12
At3g20860 [R] KOG0589 Serine/threonine protein kinase 71 2e-12
At1g54510 [R] KOG0589 Serine/threonine protein kinase 71 2e-12
At1g10940 [T] KOG0583 Serine/threonine protein kinase 71 2e-12
YPL209c [D] KOG0580 Serine/threonine protein kinase 71 2e-12
YPL141c [T] KOG0583 Serine/threonine protein kinase 71 2e-12
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 71 2e-12
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-12
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 71 2e-12
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-12
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-12
CE20717 [T] KOG0583 Serine/threonine protein kinase 71 2e-12
7301110 [T] KOG0660 Mitogen-activated protein kinase 71 2e-12
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 70 3e-12
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 3e-12
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 3e-12
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 70 3e-12
CE27177 [T] KOG4279 Serine/threonine protein kinase 70 3e-12
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 70 3e-12
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 70 3e-12
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 3e-12
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 3e-12
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 3e-12
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 70 4e-12
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 70 4e-12
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 70 4e-12
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 70 4e-12
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 4e-12
CE18366 [T] KOG0583 Serine/threonine protein kinase 70 4e-12
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 70 4e-12
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 70 4e-12
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 70 4e-12
At3g50500 [T] KOG0583 Serine/threonine protein kinase 70 4e-12
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 70 4e-12
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 4e-12
7299793 [T] KOG0583 Serine/threonine protein kinase 70 4e-12
Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1 70 5e-12
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 70 5e-12
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 70 5e-12
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 70 5e-12
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 70 5e-12
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 70 5e-12
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 70 5e-12
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 70 5e-12
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 70 5e-12
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 70 5e-12
At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 5e-12
At3g23000 [T] KOG0583 Serine/threonine protein kinase 70 5e-12
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 70 5e-12
At2g25090 [T] KOG0583 Serine/threonine protein kinase 70 5e-12
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 70 5e-12
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 5e-12
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 70 5e-12
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 70 5e-12
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 69 6e-12
Hs4502435 [T] KOG0197 Tyrosine kinases 69 6e-12
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 69 6e-12
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 69 6e-12
CE26422 [D] KOG0600 Cdc2-related protein kinase 69 6e-12
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 69 6e-12
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 69 6e-12
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 69 6e-12
CE01554 [T] KOG0986 G protein-coupled receptor kinase 69 6e-12
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 6e-12
At4g33950 [T] KOG0583 Serine/threonine protein kinase 69 6e-12
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 69 6e-12
7300559 [T] KOG4279 Serine/threonine protein kinase 69 6e-12
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 69 6e-12
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 69 8e-12
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 69 8e-12
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 69 8e-12
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 69 8e-12
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 69 8e-12
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 69 8e-12
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 69 8e-12
At5g45820 [T] KOG0583 Serine/threonine protein kinase 69 8e-12
At5g01810 [T] KOG0583 Serine/threonine protein kinase 69 8e-12
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 69 8e-12
At2g38490 [T] KOG0583 Serine/threonine protein kinase 69 8e-12
At1g60940 [T] KOG0583 Serine/threonine protein kinase 69 8e-12
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 69 8e-12
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 69 1e-11
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 69 1e-11
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 69 1e-11
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 69 1e-11
CE18454 [T] KOG4717 Serine/threonine protein kinase 69 1e-11
At5g10930 [T] KOG0583 Serine/threonine protein kinase 69 1e-11
7303211 [T] KOG4717 Serine/threonine protein kinase 69 1e-11
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 68 1e-11
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 68 1e-11
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 68 1e-11
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 68 1e-11
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 68 1e-11
ECU05g0630 [R] KOG0584 Serine/threonine protein kinase 68 1e-11
At3g04910 [R] KOG0584 Serine/threonine protein kinase 68 1e-11
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 68 1e-11
7293601 [T] KOG0577 Serine/threonine protein kinase 68 1e-11
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 68 2e-11
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 68 2e-11
Hs5174647 [T] KOG0197 Tyrosine kinases 68 2e-11
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 68 2e-11
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 68 2e-11
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 68 2e-11
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 68 2e-11
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 68 2e-11
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 68 2e-11
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 68 2e-11
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 68 2e-11
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 68 2e-11
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 68 2e-11
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 68 2e-11
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 68 2e-11
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 67 2e-11
YHR102w [T] KOG0201 Serine/threonine protein kinase 67 2e-11
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 67 2e-11
Hs22045264 [T] KOG0583 Serine/threonine protein kinase 67 2e-11
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 67 2e-11
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 67 2e-11
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 67 2e-11
CE24994 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 67 2e-11
At3g17510 [T] KOG0583 Serine/threonine protein kinase 67 2e-11
At2g45490 [D] KOG0580 Serine/threonine protein kinase 67 2e-11
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 67 2e-11
At1g49160 [R] KOG0584 Serine/threonine protein kinase 67 2e-11
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 67 2e-11
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 67 2e-11
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 67 3e-11
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 67 3e-11
Hs4507749 [T] KOG0197 Tyrosine kinases 67 3e-11
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 3e-11
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 3e-11
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 3e-11
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 3e-11
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 67 3e-11
CE24761 [D] KOG0580 Serine/threonine protein kinase 67 3e-11
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 67 4e-11
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 67 4e-11
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 67 4e-11
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 4e-11
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 4e-11
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 4e-11
At4g30960 [T] KOG0583 Serine/threonine protein kinase 67 4e-11
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 4e-11
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 4e-11
At1g48260 [T] KOG0583 Serine/threonine protein kinase 67 4e-11
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 67 4e-11
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 66 5e-11
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 66 5e-11
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 66 5e-11
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 66 5e-11
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 66 5e-11
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 66 5e-11
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 66 5e-11
CE01519 [T] KOG1027 Serine/threonine protein kinase and endoribo... 66 5e-11
At4g40010 [T] KOG0583 Serine/threonine protein kinase 66 5e-11
At3g44200 [R] KOG0589 Serine/threonine protein kinase 66 5e-11
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 66 7e-11
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 66 7e-11
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 66 7e-11
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 66 7e-11
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 66 7e-11
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 66 7e-11
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 66 7e-11
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 66 7e-11
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 66 7e-11
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 66 7e-11
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 66 7e-11
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 66 7e-11
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 66 7e-11
At5g08590 [T] KOG0583 Serine/threonine protein kinase 66 7e-11
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 66 7e-11
7297080 [T] KOG0583 Serine/threonine protein kinase 66 7e-11
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 66 7e-11
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 65 9e-11
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 65 9e-11
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 65 9e-11
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 65 9e-11
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 65 9e-11
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 9e-11
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 65 9e-11
7298698 [T] KOG4250 TANK binding protein kinase TBK1 65 9e-11
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 9e-11
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 65 9e-11
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 65 9e-11
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 65 1e-10
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 65 1e-10
SPBC337.04 [R] KOG0586 Serine/threonine protein kinase 65 1e-10
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 65 1e-10
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 65 1e-10
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 65 1e-10
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 1e-10
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 65 1e-10
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 65 1e-10
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 65 1e-10
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 65 1e-10
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 65 1e-10
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 65 1e-10
At5g55560 [R] KOG0584 Serine/threonine protein kinase 65 1e-10
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 65 1e-10
At3g04810 [R] KOG0589 Serine/threonine protein kinase 65 1e-10
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 65 1e-10
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 65 1e-10
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 65 1e-10
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 65 1e-10
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 65 1e-10
YOR233w [T] KOG0583 Serine/threonine protein kinase 65 1e-10
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 65 1e-10
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 65 1e-10
Hs4507743 [T] KOG0197 Tyrosine kinases 65 1e-10
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 65 1e-10
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 65 1e-10
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 65 1e-10
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 65 1e-10
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 65 1e-10
At1g01140 [T] KOG0583 Serine/threonine protein kinase 65 1e-10
7300106 [T] KOG0690 Serine/threonine protein kinase 65 1e-10
YDR247w [T] KOG0583 Serine/threonine protein kinase 64 2e-10
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 64 2e-10
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 64 2e-10
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 64 2e-10
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 64 2e-10
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 64 2e-10
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 2e-10
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 64 2e-10
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 2e-10
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 64 2e-10
YLR113w [T] KOG0660 Mitogen-activated protein kinase 64 3e-10
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 64 3e-10
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 64 3e-10
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 64 3e-10
Hs4507361 [T] KOG0192 Tyrosine kinase specific for activated (GT... 64 3e-10
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 64 3e-10
Hs21735566 [T] KOG0192 Tyrosine kinase specific for activated (G... 64 3e-10
Hs21735564 [T] KOG0192 Tyrosine kinase specific for activated (G... 64 3e-10
Hs21735562 [T] KOG0192 Tyrosine kinase specific for activated (G... 64 3e-10
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 64 3e-10
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 64 3e-10
Hs14756717 [T] KOG0197 Tyrosine kinases 64 3e-10
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 64 3e-10
Hs12711660 [R] KOG0584 Serine/threonine protein kinase 64 3e-10
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 64 3e-10
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 64 3e-10
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 64 3e-10
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 3e-10
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 64 3e-10
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 64 3e-10
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 64 3e-10
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 64 3e-10
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 64 3e-10
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 64 3e-10
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 64 3e-10
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 64 3e-10
At5g41990 [R] KOG0584 Serine/threonine protein kinase 64 3e-10
At5g28290 [R] KOG0589 Serine/threonine protein kinase 64 3e-10
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 64 3e-10
7296166 [T] KOG0614 cGMP-dependent protein kinase 64 3e-10
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 63 4e-10
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 63 4e-10
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 63 4e-10
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 63 4e-10
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 63 4e-10
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 63 4e-10
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 4e-10
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 4e-10
At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 4e-10
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 63 4e-10
7301734 [T] KOG0694 Serine/threonine protein kinase 63 4e-10
7295431 [D] KOG0601 Cyclin-dependent kinase WEE1 63 4e-10
YPR054w [T] KOG0660 Mitogen-activated protein kinase 63 6e-10
YKL139w [D] KOG0600 Cdc2-related protein kinase 63 6e-10
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 63 6e-10
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 63 6e-10
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 63 6e-10
Hs4826776 [T] KOG0197 Tyrosine kinases 63 6e-10
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 63 6e-10
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 63 6e-10
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 63 6e-10
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 63 6e-10
CE29298 [T] KOG0690 Serine/threonine protein kinase 63 6e-10
CE29092 [T] KOG0694 Serine/threonine protein kinase 63 6e-10
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 63 6e-10
CE21025 [D] KOG0580 Serine/threonine protein kinase 63 6e-10
CE18646 [T] KOG0690 Serine/threonine protein kinase 63 6e-10
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 63 6e-10
At3g22420 [R] KOG0584 Serine/threonine protein kinase 63 6e-10
At3g06230 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 63 6e-10
YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 62 7e-10
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 62 7e-10
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 62 7e-10
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 62 7e-10
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 7e-10
Hs22055520 [R] KOG0584 Serine/threonine protein kinase 62 7e-10
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 62 7e-10
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 62 7e-10
CE23332 [T] KOG0194 Protein tyrosine kinase 62 7e-10
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 62 7e-10
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 62 7e-10
CE02586 [T] KOG0696 Serine/threonine protein kinase 62 7e-10
CE01008 [T] KOG0583 Serine/threonine protein kinase 62 7e-10
At5g63650 [T] KOG0583 Serine/threonine protein kinase 62 7e-10
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 7e-10
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 62 1e-09
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 62 1e-09
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 62 1e-09
>YDL025c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 620
Score = 110 bits (275), Expect = 2e-24
Identities = 82/274 (29%), Positives = 133/274 (47%), Gaps = 36/274 (13%)
Query: 22 RLIQGTTCEVEIVSKSDGSKLALKKFRSWDLHN---------HHKEVCVKEYELLKKLNH 72
+L +G + V +V ++DG A K FR L+N ++ + E+ + L+H
Sbjct: 307 KLGEGASGSVSVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHH 366
Query: 73 KCIIEALDCNKRKHT--ITFPYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHN 130
+ I+E LD T + Y Y L+ MS L T +E +F Q+C G+ YLHS
Sbjct: 367 ENIVETLDMLTEGDTYLLVMEYAPYDFFNLV-MSNLMTQDEVNCYFKQLCHGVNYLHSMG 425
Query: 131 IVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKE----ACHGIRGSEQLMAPEVFQRL 186
+ HRDLKL+N +V + +K+IDFGSAV E HGI GS+ +APE+ ++
Sbjct: 426 LAHRDLKLDNCVVTKDGI-LKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQT 484
Query: 187 KYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLN--------- 237
Y+ D+WS+ I+ + FPWK K +F +T+ P +
Sbjct: 485 SYDPRVADVWSIAIIFYCMV----LKRFPWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKI 540
Query: 238 ------ISIDLCMKLLSVDVKQRLSIQDVINDSF 265
S + ++L+++ KQR+ + DV+ D +
Sbjct: 541 LRLLPRHSRTIIGRMLALEPKQRVLMNDVVKDDW 574
>SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 650
Score = 100 bits (250), Expect = 2e-21
Identities = 75/205 (36%), Positives = 107/205 (51%), Gaps = 21/205 (10%)
Query: 37 SDGSKLALKKFRSWDLHNHHKEVCVK---EYELLKKLNHKCIIEALDC---NKRKHTIT- 89
SDG A+K+FR+ +E K E+ + L+H IIE LD NK+ + +
Sbjct: 323 SDGKIFAVKEFRARRPTETEREYARKVTAEFCIGSALHHTNIIETLDIVEENKKFYEVME 382
Query: 90 -FPYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC 148
PY ++++ KM+M + F Q+ G+AYLHS + HRDLKL+N++VD S C
Sbjct: 383 YAPYDMFSIVMSGKMTMPEVY----CCFKQLLSGVAYLHSMGLAHRDLKLDNLVVD-SNC 437
Query: 149 NIKIIDFGSAVDVGPNKEA----CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
+KIIDFGSAV EA G+ GS+ +APE R Y+ VD+WS I+
Sbjct: 438 FVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLVRKLYDPRAVDIWSSAII--- 494
Query: 205 FFNNSNKPAFPWKIAKIDDVAFEAY 229
F FPWK K+ D +F +
Sbjct: 495 -FCCMALRRFPWKYPKLSDNSFRLF 518
>SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 513
Score = 100 bits (249), Expect = 2e-21
Identities = 74/228 (32%), Positives = 110/228 (47%), Gaps = 29/228 (12%)
Query: 61 VKEYELLKKLNHKCIIEALDCNKRKHTIT-----FPYYSYTVLYLMKMSMLPTFEERALW 115
+ EY L H II+ LD ++HTI PY +T + S L +
Sbjct: 289 IAEYTFASTLRHPNIIKVLDIIYKRHTILQIIEYVPYDLFTFITKGHCSALKADQ----M 344
Query: 116 FCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEA----CHGI 171
F Q+ +G+AY+HS I HRD+KL+NIM+DE+L N+KIIDFG+A E+ G+
Sbjct: 345 FFQLLDGVAYMHSLGIAHRDIKLDNIMLDENL-NVKIIDFGTAFVFHYPFESTTLMSDGV 403
Query: 172 RGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYT- 230
GS+ +APEV + Y+ + VD+WS I+ + FPWK+ D F Y
Sbjct: 404 VGSKPYVAPEVLTQKPYDPSAVDVWSCAIV----YCCIALKRFPWKVPHTSDKRFNLYVT 459
Query: 231 --KNPTTLNISI--------DLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+P T + I D +L +D R SI + ++ Q+
Sbjct: 460 QRNDPNTKSQLIESLPMNSRDTIYHMLDIDFNTRCSISGARSTTWMQQ 507
>YNL183c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 790
Score = 100 bits (248), Expect = 3e-21
Identities = 75/203 (36%), Positives = 103/203 (49%), Gaps = 17/203 (8%)
Query: 37 SDGSKLALKKFRSWDLHNHHKEVCVK----EYELLKKLNHKCIIEALDCNKRKHTI--TF 90
SD A+K+FR+ N K VK EY + LNH IIE ++ I
Sbjct: 459 SDNKIFAVKEFRT-KFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVM 517
Query: 91 PYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNI 150
Y Y L+ + MS ++EE F QI G+ YLHS + HRDLKL+N +++E +
Sbjct: 518 EYCEYD-LFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGI-V 575
Query: 151 KIIDFGSAV----DVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
K+IDFG+AV N GI GS+ +APEV KY+ PVD+WS I+ F
Sbjct: 576 KLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAII----F 631
Query: 207 NNSNKPAFPWKIAKIDDVAFEAY 229
FPWKI K+ D +F+ +
Sbjct: 632 ACMILKKFPWKIPKLRDNSFKLF 654
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 99.0 bits (245), Expect = 7e-21
Identities = 73/243 (30%), Positives = 120/243 (49%), Gaps = 9/243 (3%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L+ ++ +E ++KKLNH I+ L + + T+ Y S
Sbjct: 86 GREVAIKLIDKTALNTIARQKLYREVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGG 145
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
L YL+K + + R L F Q+ I Y HS +IVHRDLK EN+++D+ + +KI D
Sbjct: 146 ELFNYLVKNGRMRERDARVL-FRQLVSAIEYCHSKSIVHRDLKAENLLLDQQM-KLKIAD 203
Query: 155 FGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAF 214
FG + P K GS APE+F+ KY G VD WSLG++++ + S P
Sbjct: 204 FGFSTTFEP-KAPLETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGS-LPFD 261
Query: 215 PWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENHNSV 273
+ ++ D + P ++I + L K L ++ QR S+ V+ D + +
Sbjct: 262 GTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQRTSLSAVMADRWINMGYEQG 321
Query: 274 DGV 276
+G+
Sbjct: 322 NGL 324
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 94.0 bits (232), Expect = 2e-19
Identities = 68/241 (28%), Positives = 118/241 (48%), Gaps = 9/241 (3%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L+ ++ +E +++K LNH I+ + + T+ Y S
Sbjct: 121 GREVAIKVIDKTQLNTSARQKLYREVKIMKLLNHPNIVRLFQVIESERTLYLVMEYASRG 180
Query: 97 VLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
L+ L+K + + R + F Q+ I Y HS +VHRDLK EN+++D+ + NIKI D
Sbjct: 181 ELFDHLVKNGRMRERDARVI-FRQLVSAIQYCHSKFVVHRDLKAENLLLDQHM-NIKIAD 238
Query: 155 FGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAF 214
FG PN + GS APE+F KY G VD WSLG++++ + S P
Sbjct: 239 FGFGNTFDPNAQL-ETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVSGS-LPFD 296
Query: 215 PWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENHNSV 273
+ ++ + + P +++ + L K L ++ +R S+ V++D + H+
Sbjct: 297 GGTLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKWINLGHDES 356
Query: 274 D 274
D
Sbjct: 357 D 357
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 93.2 bits (230), Expect = 4e-19
Identities = 75/272 (27%), Positives = 124/272 (45%), Gaps = 45/272 (16%)
Query: 35 SKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALD-CNKRKHT-ITFPY 92
+K G +A+KKF D K++ ++E +LLK+L H+ ++ L+ C K+K + F +
Sbjct: 23 NKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEF 82
Query: 93 YSYTVLYLMKMSMLPT---FEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN 149
+T+L + + P ++ + QI GI + HSHNI+HRD+K ENI+V +S
Sbjct: 83 VDHTILD--DLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV- 139
Query: 150 IKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS 209
+K+ DFG A + E + APE+ G VD+W++G ++ E F
Sbjct: 140 VKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMF--M 197
Query: 210 NKPAFPWKIAKIDDVAF-------------EAYTKNPTTLNIS----------------- 239
+P FP + ID + E + KNP +
Sbjct: 198 GEPLFPGD-SDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKL 256
Query: 240 ----IDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
IDL K L +D +R ++++ FFQ
Sbjct: 257 SEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQ 288
>YDL214c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 699
Score = 91.7 bits (226), Expect = 1e-18
Identities = 67/215 (31%), Positives = 107/215 (49%), Gaps = 16/215 (7%)
Query: 25 QGTTCEVEIVSKS-DGSKLALKKFRSWDLHNHHKEVC---VKEYELLKKLNHKCIIEALD 80
+G+ +V++V + D ALK++RS ++ + EY + L + I E L+
Sbjct: 369 EGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLE 428
Query: 81 CNKRKHTI--TFPYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKL 138
K I Y Y L+ + MS +EE F Q+ G+ YLH + HRDLKL
Sbjct: 429 ILYEKGKIFQILEYCEYD-LFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKL 487
Query: 139 ENIMVDESLCNIKIIDFGSA----VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVD 194
+N +V +K+IDFG++ + +GI GS+ ++PEVF +Y+ +D
Sbjct: 488 DNCVVTRRGI-LKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALD 546
Query: 195 MWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAY 229
+WS+GI+ F FPWK K+ DV F+A+
Sbjct: 547 VWSVGIIFFCMITR----RFPWKYPKVKDVQFKAF 577
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 90.9 bits (224), Expect = 2e-18
Identities = 69/227 (30%), Positives = 112/227 (48%), Gaps = 30/227 (13%)
Query: 53 HNHHKEV----CVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVL--YLMKMS 104
H++H + +E ++K ++H ++ + NK + + Y L YL+
Sbjct: 150 HSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKG 209
Query: 105 MLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPN 164
LP E +F QI EG++Y HS NI HRDLK EN+++D+ IKI DFG A PN
Sbjct: 210 KLPE-REAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPN 268
Query: 165 ---KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFP 215
K +C GS +PE+ Y G P D+WS GI++F FN+ N
Sbjct: 269 KLLKTSC----GSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKL- 323
Query: 216 WKIAKIDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRLSIQDVI 261
+ K+ ++ P+ L+ DL K+L +D ++R++ Q+++
Sbjct: 324 --LLKVQSGKYQM----PSNLSSEARDLISKILVIDPEKRITTQEIL 364
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 89.7 bits (221), Expect = 4e-18
Identities = 67/238 (28%), Positives = 119/238 (49%), Gaps = 25/238 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G ++A+K L+ + +E +++K+L+H I++ + + T+ Y VL
Sbjct: 145 GHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTL------YLVL 198
Query: 99 ----------YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC 148
YL+ + E RA F QI + YLHS NI+HRDLK EN+++D+ +
Sbjct: 199 EYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYLHSKNIIHRDLKAENLLLDQDM- 256
Query: 149 NIKIIDFG--SAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
NIKI DFG + +G + GS APE+F KY+G VD+WSLG++++
Sbjct: 257 NIKIADFGFSNTFSLGNKLDT---FCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLV 313
Query: 207 NNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVIND 263
+ S P + ++ + + P ++ + L K L ++ ++R S+ +++ D
Sbjct: 314 SGS-LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKD 370
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 89.7 bits (221), Expect = 4e-18
Identities = 67/238 (28%), Positives = 119/238 (49%), Gaps = 25/238 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G ++A+K L+ + +E +++K+L+H I++ + + T+ Y VL
Sbjct: 193 GHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTL------YLVL 246
Query: 99 ----------YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC 148
YL+ + E RA F QI + YLHS NI+HRDLK EN+++D+ +
Sbjct: 247 EYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYLHSKNIIHRDLKAENLLLDQDM- 304
Query: 149 NIKIIDFG--SAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
NIKI DFG + +G + GS APE+F KY+G VD+WSLG++++
Sbjct: 305 NIKIADFGFSNTFSLGNKLDT---FCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLV 361
Query: 207 NNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVIND 263
+ S P + ++ + + P ++ + L K L ++ ++R S+ +++ D
Sbjct: 362 SGS-LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKD 418
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 89.7 bits (221), Expect = 4e-18
Identities = 73/262 (27%), Positives = 129/262 (48%), Gaps = 22/262 (8%)
Query: 22 RLIQGTTCEVEI-VSKSDGSKLALKKFRSWDLHNHHKEVCVK-EYELLKKLNHKCIIEAL 79
+L QGT +V++ ++K G ++A+K + + V ++ E +++ ++H II
Sbjct: 87 KLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIY 146
Query: 80 DC--NKRKHTITFPYYSYTVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRD 135
+ N+ K + + + LY L + +L E R + F Q+ + Y H H I HRD
Sbjct: 147 EVFENREKMVLVMEFAAGGELYDYLSERKVLTEEEARRI-FRQVATAVYYCHKHKICHRD 205
Query: 136 LKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDM 195
LKLENI++DE N KI DFG + +V ++ GS +PE+ + Y+G VD
Sbjct: 206 LKLENILLDEK-GNAKIADFGLS-NVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDC 263
Query: 196 WSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSV 249
WSLG++++ F+ SN +I++ D P + + L +L+V
Sbjct: 264 WSLGVLLYTLVYGSMPFDGSNFKRLVKQISQGD-------YYEPRKPSRASTLIRDMLTV 316
Query: 250 DVKQRLSIQDVINDSFFQENHN 271
++R SI+ + + + EN N
Sbjct: 317 CPRKRASIEQICSHWWVNENDN 338
>CE27899 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 318
Score = 89.4 bits (220), Expect = 6e-18
Identities = 75/268 (27%), Positives = 128/268 (46%), Gaps = 28/268 (10%)
Query: 23 LIQGTTCEVEIV--SKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLN----HKCII 76
L +GT +V + SK+ K+A+K+ + E E+ + K L+ H+ +I
Sbjct: 27 LSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSERFVEHIKTEFAIHKGLSKIGGHRNVI 86
Query: 77 EALDCNKRK--HTITFPYYSYTVLYLMKMSMLPTFEERA-LWFCQICEGIAYLHSHNIVH 133
++ K +T+ Y L+ + + E A +F Q+ G+ ++H H IVH
Sbjct: 87 SMMEMRKGSDCYTLLKEYADGGDLFKKLETEGEQYSENAQCFFKQLISGLKFIHEHEIVH 146
Query: 134 RDLKLENIMVDESLCN-----IKIIDFGSAVDVGPNKEACHGIR--GSEQLMAPEVFQRL 186
RD+KLEN+++ +S N +KI DFG A + + E + GS APEV+ +
Sbjct: 147 RDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAAPEVYSKQ 206
Query: 187 KYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAY-TKNPTTLNI------- 238
+ G P D+WS G+++ PW A DV + A+ K T N+
Sbjct: 207 GHRGPPTDVWSSGVILMAMLT----AGLPWDCAHRKDVDYAAWIDKKFRTDNLWNDISDR 262
Query: 239 SIDLCMKLLSVDVKQRLSIQDVINDSFF 266
++ L K+L V+V +R+SI+ + D +F
Sbjct: 263 ALALLRKILCVNVSERVSIEQIEADPWF 290
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 89.4 bits (220), Expect = 6e-18
Identities = 63/242 (26%), Positives = 114/242 (47%), Gaps = 20/242 (8%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNK-RKHTITFPYYSYTVLY 99
K+A+KK + E +EY + K + HK I++ + + F +
Sbjct: 32 KVAMKKINIFGAPKEFLEQIQQEYYIQKNMKHKNIVKMYGMSMDTEFCYLFQEFVTGGDL 91
Query: 100 LMKMSM---LPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG 156
K+ +P + + + Q+ G+ Y+H IVHRD+K +N++++ S +KI DFG
Sbjct: 92 FEKIDFENGMPVNQVKG-YLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDA-LKIADFG 149
Query: 157 SAVD--VGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAF 214
+ V + H G+ MAPE+F + K+ G PVD+WS GI++F +
Sbjct: 150 LSTRFIVDDKEILLHERIGTTPFMAPELFAKKKHRGPPVDIWSAGILVFSLLTGN----L 205
Query: 215 PWKIAKIDDVAFEAYTKNPTTLNI--------SIDLCMKLLSVDVKQRLSIQDVINDSFF 266
PW K D+ + + N T+ N + KLL +V +R +I+++ +D +
Sbjct: 206 PWDEPKESDILYSQWMNNKTSKNCIWYGLSTPVVRFLKKLLKENVNERATIEEIESDPWL 265
Query: 267 QE 268
++
Sbjct: 266 ED 267
>CE20636 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 687
Score = 89.4 bits (220), Expect = 6e-18
Identities = 75/268 (27%), Positives = 128/268 (46%), Gaps = 28/268 (10%)
Query: 23 LIQGTTCEVEIV--SKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLN----HKCII 76
L +GT +V + SK+ K+A+K+ + E E+ + K L+ H+ +I
Sbjct: 27 LSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSERFVEHIKTEFAIHKGLSKIGGHRNVI 86
Query: 77 EALDCNKRK--HTITFPYYSYTVLYLMKMSMLPTFEERA-LWFCQICEGIAYLHSHNIVH 133
++ K +T+ Y L+ + + E A +F Q+ G+ ++H H IVH
Sbjct: 87 SMMEMRKGSDCYTLLKEYADGGDLFKKLETEGEQYSENAQCFFKQLISGLKFIHEHEIVH 146
Query: 134 RDLKLENIMVDESLCN-----IKIIDFGSAVDVGPNKEACHGIR--GSEQLMAPEVFQRL 186
RD+KLEN+++ +S N +KI DFG A + + E + GS APEV+ +
Sbjct: 147 RDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAAPEVYSKQ 206
Query: 187 KYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAY-TKNPTTLNI------- 238
+ G P D+WS G+++ PW A DV + A+ K T N+
Sbjct: 207 GHRGPPTDVWSSGVILMAMLT----AGLPWDCAHRKDVDYAAWIDKKFRTDNLWNDISDR 262
Query: 239 SIDLCMKLLSVDVKQRLSIQDVINDSFF 266
++ L K+L V+V +R+SI+ + D +F
Sbjct: 263 ALALLRKILCVNVSERVSIEQIEADPWF 290
Score = 67.8 bits (164), Expect = 2e-11
Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 14/190 (7%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVK-EYELLKKLN---HKCIIEALDCNKR-KHTITFPYY 93
G +A+K+ + H + VK EY L K+L+ H+ +I L +H Y
Sbjct: 355 GEAVAMKEIEASGEHVEQITLNVKKEYILTKRLSAPGHENVIRFLSIRTMPEHYFLIMEY 414
Query: 94 SYTVLYLMKMSM--LPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIK 151
+ K+S T + +F Q+ G+ Y+HS + HRD+K EN+M+ ++ +K
Sbjct: 415 ADGGDLFDKISSEYRLTSSQAHGYFKQLIAGLRYIHSKGVTHRDIKPENLMLTKAGV-LK 473
Query: 152 IIDFG-SAVDVGPNKEACHGIR-GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS 209
I DFG + + +E+ R G+ Q APEV +Y G PVD+WS G+++
Sbjct: 474 ITDFGLGTLHIIKGEESLMDTRCGTPQYAAPEVLVGNQYRGPPVDIWSAGVVLINMLTGH 533
Query: 210 NKPAFPWKIA 219
+ PWK A
Sbjct: 534 S----PWKKA 539
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 88.6 bits (218), Expect = 1e-17
Identities = 77/273 (28%), Positives = 122/273 (44%), Gaps = 47/273 (17%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCII---EALDCNKRKHTITFPY 92
K +ALKK R ++E LLK++ H I+ + + KR + +
Sbjct: 24 KVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNIVKYDDVVHSEKRLYLV---- 79
Query: 93 YSYTVLYLMK-MSMLPTFEERA----LWFCQICEGIAYLHSHNIVHRDLKLENIMVDESL 147
+ Y L L K M P F + + QI GIAY HSH ++HRDLK +N+++D
Sbjct: 80 FEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRT 139
Query: 148 CNIKIIDFGSAVDVG-PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
++K+ DFG A G P + H + + APE+ + TPVD+WS+G + E
Sbjct: 140 NSLKLADFGLARAFGIPVRTFTHEV-VTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEMI 198
Query: 207 NNSNKPAFP--------WKIAKIDDVAFE--------------AYTK-NPTTLNI----- 238
S KP FP +KI +I +E A+ K PT L
Sbjct: 199 --SQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYKSAFPKWKPTDLETFVPNL 256
Query: 239 ---SIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+DL K+L +D +R++ + + +F++
Sbjct: 257 DPDGVDLLSKMLLMDPTKRINARAALEHEYFKD 289
>YOR267c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 759
Score = 88.2 bits (217), Expect = 1e-17
Identities = 67/209 (32%), Positives = 100/209 (47%), Gaps = 18/209 (8%)
Query: 33 IVSKSDGSKLALKKFRSWDLHNHHKEV---CVKEYELLKKLNHKCIIEALDC-NKRKHTI 88
+V +DG+ A+K+FR + KE C E+ + L+H +IE +D + K
Sbjct: 232 LVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNK 291
Query: 89 TFPYYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLEN-IMVDE 145
+ Y + + M + C Q+ EG+ YLHS + HRDLKL+N +M +
Sbjct: 292 YYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQ 351
Query: 146 SLCNIKIIDFGSAV----DVGPNKEACHGIRGSEQLMAPEVFQRLK-YEGTPVDMWSLGI 200
+ +K+IDFGSAV HGI GS+ +APEV K Y+ VD+WS+GI
Sbjct: 352 GI--LKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGI 409
Query: 201 MMFEFFNNSNKPAFPWKIAKIDDVAFEAY 229
+ + FPWK + D F Y
Sbjct: 410 I----YCCMVLKRFPWKAPRDSDDNFRLY 434
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 87.4 bits (215), Expect = 2e-17
Identities = 71/230 (30%), Positives = 113/230 (48%), Gaps = 11/230 (4%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVK-EYELLKKLNHKCIIEALDC--NKRKHTITFPYYSY 95
G +A+K R + + V ++ E E++ LNH II + NK K I Y S
Sbjct: 78 GRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASK 137
Query: 96 TVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKII 153
LY + + L E R +F QI + Y H + +VHRDLKLENI++D++ CNIKI
Sbjct: 138 GELYDYISERRRLSERETRH-FFRQIVSAVHYCHKNGVVHRDLKLENILLDDN-CNIKIA 195
Query: 154 DFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF-FNNSNKP 212
DFG + ++ + GS +PE+ Y G VD W+LG++++ +
Sbjct: 196 DFGLS-NLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFD 254
Query: 213 AFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVIN 262
F K I ++ Y + PT + + L +L V+ +R +I+D+ N
Sbjct: 255 GFDHK-NLIRQISSGEY-REPTQPSDARGLIRWMLMVNPDRRATIEDIAN 302
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 85.9 bits (211), Expect = 6e-17
Identities = 69/239 (28%), Positives = 118/239 (48%), Gaps = 13/239 (5%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L+ + +E ++K LNH I++ + + + T+ Y S
Sbjct: 83 GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGG 142
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
+ YL+ + E RA F QI + Y H IVHRDLK EN+++D + NIKI D
Sbjct: 143 EVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKYIVHRDLKAENLLLDGDM-NIKIAD 200
Query: 155 FGSAVD--VGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKP 212
FG + + VG + GS APE+FQ KY+G VD+WSLG++++ + S P
Sbjct: 201 FGFSNEFTVGNKLDT---FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS-LP 256
Query: 213 AFPWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+ ++ + + P ++ + L KLL ++ +R S++ ++ D + H
Sbjct: 257 FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGH 315
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 85.9 bits (211), Expect = 6e-17
Identities = 60/178 (33%), Positives = 89/178 (49%), Gaps = 21/178 (11%)
Query: 99 YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA 158
Y+ + LP E R +F QI G++Y H+H IVHRDLK EN+++D + NIKI DFG +
Sbjct: 112 YITRKGALPIRESRR-YFQQIISGVSYCHNHMIVHRDLKPENLLLDANK-NIKIADFGLS 169
Query: 159 ---VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNS 209
D AC GS APE+ Y G VD+WS G++++ F++
Sbjct: 170 NYMTDGDLLSTAC----GSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQ 225
Query: 210 NKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
N P KI YT + + DL +L VD +R ++ ++N S+F+
Sbjct: 226 NVPTLFAKIKS------GRYTVPYSMEKQAADLISTMLQVDPVKRADVKRIVNHSWFR 277
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 85.5 bits (210), Expect = 8e-17
Identities = 55/160 (34%), Positives = 85/160 (52%), Gaps = 16/160 (10%)
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLM 178
I + YLH++NIVHRDLK+ENIM+ +S IKIIDFG + ++ +++ H GS
Sbjct: 253 IASALIYLHANNIVHRDLKIENIMISDS-SEIKIIDFGLS-NIYDSRKQLHTFCGSLYFA 310
Query: 179 APEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKN 232
APE+ + Y G VD+WS G+++F F++ N KI + +
Sbjct: 311 APELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIK-------QGKVEY 363
Query: 233 PTTLNIS-IDLCMKLLSVDVKQRLSIQDVINDSFFQENHN 271
P L+I I L K+L VD K+R +++ V+ + N
Sbjct: 364 PQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFN 403
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 85.5 bits (210), Expect = 8e-17
Identities = 69/228 (30%), Positives = 110/228 (47%), Gaps = 19/228 (8%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYTVLYLMKMSMLPTFEERAL-WFCQ 118
+E ++K L+H ++ D + + + Y L+ + + P E A+ F Q
Sbjct: 76 REIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQ 135
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA---VDVGPNKEACHGIRGSE 175
I GI+Y H+ IVHRDLK EN+++D S NIKI DFG A D + +C GS
Sbjct: 136 IIIGISYCHALGIVHRDLKPENLLLD-SFYNIKIADFGMAALQTDADLLETSC----GSP 190
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYT---KN 232
APE+ L YEG D+WS G+++F + + F + + D+ + +
Sbjct: 191 HYAAPEIVSGLPYEGFASDVWSCGVILFALL--TGRLPFDEENGNVRDLLLKVQKGQFEM 248
Query: 233 PTTLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVS 277
P IS DL K+L VD +QR+ I+D+++ ++ D S
Sbjct: 249 PNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKS 296
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 85.5 bits (210), Expect = 8e-17
Identities = 65/237 (27%), Positives = 116/237 (48%), Gaps = 9/237 (3%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L++ + +E ++K LNH I++ + + + T+ Y S
Sbjct: 43 GKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGG 102
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
+ YL+ + E RA F QI + Y H IVHRDLK EN+++D + NIKI D
Sbjct: 103 EVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKFIVHRDLKAENLLLDADM-NIKIAD 160
Query: 155 FGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAF 214
FG + + + GS APE+FQ KY+G VD+WSLG++++ + S P
Sbjct: 161 FGFSNEFTFGNKL-DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS-LPFD 218
Query: 215 PWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+ ++ + + P ++ + L K L ++ +R +++ ++ D + H
Sbjct: 219 GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGH 275
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 85.5 bits (210), Expect = 8e-17
Identities = 65/237 (27%), Positives = 116/237 (48%), Gaps = 9/237 (3%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L++ + +E ++K LNH I++ + + + T+ Y S
Sbjct: 43 GKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGG 102
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
+ YL+ + E RA F QI + Y H IVHRDLK EN+++D + NIKI D
Sbjct: 103 EVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKFIVHRDLKAENLLLDADM-NIKIAD 160
Query: 155 FGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAF 214
FG + + + GS APE+FQ KY+G VD+WSLG++++ + S P
Sbjct: 161 FGFSNEFTFGNKL-DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS-LPFD 218
Query: 215 PWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+ ++ + + P ++ + L K L ++ +R +++ ++ D + H
Sbjct: 219 GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGH 275
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 85.5 bits (210), Expect = 8e-17
Identities = 65/237 (27%), Positives = 116/237 (48%), Gaps = 9/237 (3%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L++ + +E ++K LNH I++ + + + T+ Y S
Sbjct: 76 GKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGG 135
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
+ YL+ + E RA F QI + Y H IVHRDLK EN+++D + NIKI D
Sbjct: 136 EVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKFIVHRDLKAENLLLDADM-NIKIAD 193
Query: 155 FGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAF 214
FG + + + GS APE+FQ KY+G VD+WSLG++++ + S P
Sbjct: 194 FGFSNEFTFGNKL-DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS-LPFD 251
Query: 215 PWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+ ++ + + P ++ + L K L ++ +R +++ ++ D + H
Sbjct: 252 GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGH 308
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 85.5 bits (210), Expect = 8e-17
Identities = 58/175 (33%), Positives = 90/175 (51%), Gaps = 7/175 (4%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L+ + +E ++K LNH I++ + + + T+ Y S
Sbjct: 82 GREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAG 141
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
+ YL+ + E RA F QI + Y H NIVHRDLK EN+++D NIKI D
Sbjct: 142 EVFDYLVSHGRMKEKEARAK-FRQIVSAVHYCHQKNIVHRDLKAENLLLDAE-ANIKIAD 199
Query: 155 FGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS 209
FG + + + GS APE+FQ KY+G VD+WSLG++++ + S
Sbjct: 200 FGFSNEFTLGSKL-DTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGS 253
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 85.1 bits (209), Expect = 1e-16
Identities = 62/236 (26%), Positives = 112/236 (47%), Gaps = 17/236 (7%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF-------- 90
G ++A+K L+ + +E ++K L+H I++ + + T+
Sbjct: 174 GKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGG 233
Query: 91 PYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNI 150
+ Y VL+ +E + F QI + Y H I+HRDLK EN+++D L NI
Sbjct: 234 EVFDYLVLHGRMKE-----KEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSEL-NI 287
Query: 151 KIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSN 210
KI DFG + + P + GS APE+FQ KY+G VD+WSLG++++ + S
Sbjct: 288 KIADFGFSNEFTPGSKL-DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS- 345
Query: 211 KPAFPWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSF 265
P + ++ + + P ++ + L K L ++ +R S++ ++ D +
Sbjct: 346 LPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKW 401
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 84.7 bits (208), Expect = 1e-16
Identities = 80/252 (31%), Positives = 119/252 (46%), Gaps = 40/252 (15%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCV-KEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTV 97
G K+A+K + N E+ V +E ++L+ L H II ++ I P Y V
Sbjct: 42 GHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHII------RQYEVIETPNDIYVV 95
Query: 98 L----------YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESL 147
+ Y+++ L E R L F QI G+ Y H + IVHRDLK EN+++D S
Sbjct: 96 MEYVKSGELFDYIVEKGKLQEDEARHL-FQQIISGVEYCHRNMIVHRDLKPENVLLD-SQ 153
Query: 148 CNIKIIDFGSAVDVGPN---KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
CNIKI+DFG + + K +C GS APEV Y G VD+WS G++++
Sbjct: 154 CNIKIVDFGLSNVMHDGHFLKTSC----GSPNYAAPEVISGKPY-GPDVDIWSCGVILYA 208
Query: 205 F------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQ 258
F++ N P KI + YT + + DL ++L VD R+SI
Sbjct: 209 LLCGTLPFDDENIPNVFEKIKR------GMYTLPNHLSHFARDLIPRMLMVDPTMRISIT 262
Query: 259 DVINDSFFQENH 270
++ +F NH
Sbjct: 263 EIRQHPWF-NNH 273
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 84.3 bits (207), Expect = 2e-16
Identities = 77/246 (31%), Positives = 114/246 (46%), Gaps = 28/246 (11%)
Query: 39 GSKLALK-----KFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFP 91
G K+A+K K RS D+ + +E + LK H II+ I
Sbjct: 41 GHKVAVKILNRQKIRSLDVVGKIR----REIQNLKLFRHPHIIKLYQVISTPSDIFMVME 96
Query: 92 YYSYTVL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN 149
Y S L Y+ K L E R L F QI G+ Y H H +VHRDLK EN+++D + N
Sbjct: 97 YVSGGELFDYICKNGRLDEKESRRL-FQQILSGVDYCHRHMVVHRDLKPENVLLDAHM-N 154
Query: 150 IKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF---- 205
KI DFG + ++ + E GS APEV Y G VD+WS G++++
Sbjct: 155 AKIADFGLS-NMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGT 213
Query: 206 --FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVIND 263
F++ + P KI D + + NP+ I L +L VD +R SI+D+
Sbjct: 214 LPFDDDHVPTLFKKIC--DGIFYTPQYLNPSV----ISLLKHMLQVDPMKRASIKDIREH 267
Query: 264 SFFQEN 269
+F+++
Sbjct: 268 EWFKQD 273
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 84.3 bits (207), Expect = 2e-16
Identities = 77/266 (28%), Positives = 116/266 (42%), Gaps = 39/266 (14%)
Query: 31 VEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF 90
+E K +K A+KK + ++ +E +LK + H+ II +
Sbjct: 131 IEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHL------EQVFET 184
Query: 91 PYYSYTVLYLMKMSMLPTF--------EERALWFCQ-ICEGIAYLHSHNIVHRDLKLENI 141
P Y V+ L + L E W Q + IAYLH+++IVHRDLKLENI
Sbjct: 185 PKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENI 244
Query: 142 MVDESL--------CNIKIIDFGSAVDVGPNKEA-CHGIRGSEQLMAPEVFQRLKYEGTP 192
MV SL NIK+ DFG AV EA G+ MAPEV Y
Sbjct: 245 MVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY-SQQ 303
Query: 193 VDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKN----PTTLNISIDLCMK--- 245
D+WS+G++M+ +P F +A ++ FE K + SI C K
Sbjct: 304 CDIWSIGVVMYMLLR--GEPPF---LASSEEKLFELIRKGELHFENAVWNSISDCAKSVL 358
Query: 246 --LLSVDVKQRLSIQDVINDSFFQEN 269
L+ VD R++ ++++++ + N
Sbjct: 359 KQLMKVDPAHRITAKELLDNQWLTGN 384
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 84.0 bits (206), Expect = 2e-16
Identities = 73/242 (30%), Positives = 113/242 (46%), Gaps = 25/242 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCV-KEYELLKKLNHKCIIEALDCNKRKHTITFPY-YSYT 96
G K+ALK L + + +E L+ L H II+ D K K I Y+
Sbjct: 78 GQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN 137
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
L Y+++ + E R +F QI + Y H H IVHRDLK EN+++DE L N+KI D
Sbjct: 138 ELFDYIVQRDKMSEQEARR-FFQQIISAVEYCHRHKIVHRDLKPENLLLDEHL-NVKIAD 195
Query: 155 FGSA---VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------ 205
FG + D K +C GS APEV Y G VD+WS G++++
Sbjct: 196 FGLSNIMTDGNFLKTSC----GSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLP 251
Query: 206 FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSF 265
F++ + P +++ YT + L ++L V+ R+SI +++ D +
Sbjct: 252 FDDESIPVL------FKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDW 305
Query: 266 FQ 267
F+
Sbjct: 306 FK 307
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 84.0 bits (206), Expect = 2e-16
Identities = 51/157 (32%), Positives = 79/157 (49%), Gaps = 5/157 (3%)
Query: 111 ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHG 170
E A + QI + +A+ H HRDLKLENI++ + IKI DFG A V PN
Sbjct: 104 EAAHYLSQILDAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMAT-VEPNDSCLEN 162
Query: 171 IRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKI--DDVAFEA 228
GS +APE+ Y G P D+WS G++++ SNK F + + + + A
Sbjct: 163 YCGSLHYLAPEIVSHKPYRGAPADVWSCGVILYSLL--SNKLPFGGQNTDVIYNKIRHGA 220
Query: 229 YTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSF 265
Y + + + DL ++L V+ R++I +V + F
Sbjct: 221 YDLPSSISSAAQDLLHRMLDVNPSTRITIPEVFSHPF 257
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 83.6 bits (205), Expect = 3e-16
Identities = 65/206 (31%), Positives = 101/206 (48%), Gaps = 14/206 (6%)
Query: 62 KEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLY--LMKMSMLPTFEERALWFC 117
+E ++ LNH II+ + NK K + Y S LY + + LP E R + F
Sbjct: 122 REIRIMSALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRI-FR 180
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
QI + Y H H + HRDLKLENI++D++ N KI DFG + + +K GS
Sbjct: 181 QITSAVLYCHKHRVAHRDLKLENILLDQN-NNAKIADFGLS-NYFADKNLLTTFCGSPLY 238
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS---NKPAFPWKIAKIDDVAFEAYTKNPT 234
+PE+ Y+G VD WSLGI+++ S + F + +I A+ P
Sbjct: 239 ASPEIINGTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAY----FEPE 294
Query: 235 TLNISIDLCMKLLSVDVKQRLSIQDV 260
T + + L +L V+ ++R +I D+
Sbjct: 295 TPSTASMLIRNMLRVNPERRATIFDI 320
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 83.2 bits (204), Expect = 4e-16
Identities = 59/177 (33%), Positives = 93/177 (52%), Gaps = 15/177 (8%)
Query: 99 YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA 158
Y++K L T E R +F QI G+ Y H H +VHRDLK EN+++DE N+KI DFG +
Sbjct: 113 YIVKHGRLKTAEARR-FFQQIISGVDYCHRHMVVHRDLKPENLLLDEQ-NNVKIADFGLS 170
Query: 159 VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKP 212
++ + + GS APEV Y G VD+WS G++++ F++ + P
Sbjct: 171 -NIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVP 229
Query: 213 AFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQEN 269
+ KI K + + P ++L +L VD +R +I+DVI +FQ++
Sbjct: 230 SLFRKI-KSGVFPTPDFLERPI-----VNLLHHMLCVDPMKRATIKDVIAHEWFQKD 280
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 83.2 bits (204), Expect = 4e-16
Identities = 59/177 (33%), Positives = 93/177 (52%), Gaps = 15/177 (8%)
Query: 99 YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA 158
Y++K L T E R +F QI G+ Y H H +VHRDLK EN+++DE N+KI DFG +
Sbjct: 113 YIVKHGRLKTAEARR-FFQQIISGVDYCHRHMVVHRDLKPENLLLDEQ-NNVKIADFGLS 170
Query: 159 VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKP 212
++ + + GS APEV Y G VD+WS G++++ F++ + P
Sbjct: 171 -NIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVP 229
Query: 213 AFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQEN 269
+ KI K + + P ++L +L VD +R +I+DVI +FQ++
Sbjct: 230 SLFRKI-KSGVFPTPDFLERPI-----VNLLHHMLCVDPMKRATIKDVIAHEWFQKD 280
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 83.2 bits (204), Expect = 4e-16
Identities = 49/158 (31%), Positives = 87/158 (55%), Gaps = 9/158 (5%)
Query: 51 DLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLMKMSMLPT 108
D+H+ +E+ E+L+KL H+ IIE LD N R+ + + + +++
Sbjct: 46 DIHSLRQEI-----EILRKLKHENIIEMLDSFENAREFCVVTEFAQGELFEILEDDKCLP 100
Query: 109 FEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEAC 168
E+ Q+ + + YLHS+ I+HRD+K +NI++ +K+ DFG A + N
Sbjct: 101 EEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAGSV-VKLCDFGFARAMSTNTVVL 159
Query: 169 HGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
I+G+ MAPE+ + Y+ T VD+WSLG++++E +
Sbjct: 160 RSIKGTPLYMAPELVKEQPYDRT-VDLWSLGVILYELY 196
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 82.8 bits (203), Expect = 5e-16
Identities = 58/160 (36%), Positives = 83/160 (51%), Gaps = 6/160 (3%)
Query: 112 RALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGI 171
R +W Q+C I YLH VHRDLKLENI +D++ N+K+ DFG + D ++
Sbjct: 127 RIMW--QLCCAIQYLHRQGCVHRDLKLENIFLDKAY-NVKLGDFGFSRDSDCSRRTFMNT 183
Query: 172 R-GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYT 230
R G+ APE+ Q KY G VD+WSLGI+M+ P ++ +
Sbjct: 184 RCGTVAYCAPELVQGHKYIGECVDIWSLGIIMYALL-IGRLPFDEDDVSLTEQKIINECP 242
Query: 231 KNPTTLN-ISIDLCMKLLSVDVKQRLSIQDVINDSFFQEN 269
+ P TL+ S L LL D + R SI +I+ +F+EN
Sbjct: 243 QYPETLSKNSSSLLKSLLCKDYRLRPSIDQIISHPYFKEN 282
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 82.4 bits (202), Expect = 7e-16
Identities = 63/202 (31%), Positives = 99/202 (48%), Gaps = 17/202 (8%)
Query: 18 NDSPRLIQGTTCEVEIVSKSDGSKLAL---KKFRSWDLH-NHHKEVCVKEYELLKKLNHK 73
N +L QG + V + G +L + +S DL KE+ + E ++++ H
Sbjct: 310 NVKHKLGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTRKELILNEITVMRESIHP 369
Query: 74 CIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFCQI-------CEGIAYL 126
I+ LD + + + Y+ S+ E+ L QI C+GI +L
Sbjct: 370 NIVTYLD----SFLVRERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICLETCKGIQHL 425
Query: 127 HSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRL 186
H+ NI+HRD+K +N+++D S NIKI DFG + + G+ MAPEV ++
Sbjct: 426 HARNIIHRDIKSDNVLLDNS-GNIKITDFGFCARLSNRTNKRVTMVGTPYWMAPEVVKQN 484
Query: 187 KYEGTPVDMWSLGIMMFEFFNN 208
+Y GT VD+WSLGIM+ E N
Sbjct: 485 EY-GTKVDIWSLGIMIIEMIEN 505
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 82.4 bits (202), Expect = 7e-16
Identities = 65/239 (27%), Positives = 117/239 (48%), Gaps = 13/239 (5%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYT 96
G ++A+K L+ + +E ++K LNH I++ + + + T+ Y S
Sbjct: 79 GREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETQKTLYLIMEYASGG 138
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
+ YL+ + E R+ F QI + Y H IVHRDLK EN+++D + NIKI D
Sbjct: 139 KVFDYLVAHGRMKEKEARSK-FRQIVSAVQYCHQKRIVHRDLKAENLLLDADM-NIKIAD 196
Query: 155 FGSAVD--VGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKP 212
FG + + VG + GS APE+FQ KY+G VD+WSLG++++ + S P
Sbjct: 197 FGFSNEFTVGGKLDT---FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS-LP 252
Query: 213 AFPWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+ ++ + + P ++ + L + L ++ +R +++ ++ D + H
Sbjct: 253 FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGH 311
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 82.0 bits (201), Expect = 9e-16
Identities = 65/212 (30%), Positives = 104/212 (48%), Gaps = 37/212 (17%)
Query: 22 RLIQGTTCEVEIVSKSD-GSKLALK----KFRSWDLHNHHKEVCVKEYELLKKLNHKCII 76
RL GT EV + K D G ++A+K KF SW+ + + ++E + LKKLNH II
Sbjct: 50 RLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWE-----EAMSLREVKSLKKLNHPNII 104
Query: 77 EALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWF---------CQICEGIAYLH 127
+ + + + Y V M+ ++ ++R +F Q+ +G+A++H
Sbjct: 105 KLREVIRENDIL------YFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMH 158
Query: 128 SHNIVHRDLKLENIMVDESLCN----IKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVF 183
+ HRD+K ENIM CN +KI DFG A ++ +K + APE+
Sbjct: 159 KNGFFHRDMKPENIM-----CNGTELVKIADFGLAREI-RSKPPYTDYVSTRWYRAPEIL 212
Query: 184 QRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFP 215
R +P+DMW+LG +M E + +P FP
Sbjct: 213 LRSTSYNSPIDMWALGCIMAELY--ILRPLFP 242
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 81.6 bits (200), Expect = 1e-15
Identities = 65/212 (30%), Positives = 103/212 (47%), Gaps = 30/212 (14%)
Query: 64 YELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFCQICEGI 123
Y +L+ HK ++E L +++ +T P Y ++ QI +
Sbjct: 114 YLILELCEHKSLMELL---RKRKQLTEPEVRYLMM-------------------QILGAL 151
Query: 124 AYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEV- 182
Y+H ++HRDLKL NIM+DES N+KI DFG A + ++E I G+ +APE+
Sbjct: 152 KYMHKKRVIHRDLKLGNIMLDES-NNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEIL 210
Query: 183 FQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKN-PTTLNISI- 240
F + VD+WS G++M+ KP F K K +A + + P+ ++IS
Sbjct: 211 FNSKEGHSFEVDLWSAGVVMYALL--IGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAE 268
Query: 241 --DLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
DL LL+ D R SI D+++ FF +
Sbjct: 269 AKDLISSLLTHDPSIRPSIDDIVDHEFFHTGY 300
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 81.6 bits (200), Expect = 1e-15
Identities = 66/220 (30%), Positives = 103/220 (46%), Gaps = 19/220 (8%)
Query: 63 EYELLKKLNHKCIIEALD----CNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFCQ 118
E E LK L H+ I + NK + + Y++ L E R + F Q
Sbjct: 57 EIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVV-FRQ 115
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKE-ACHGIRGSEQL 177
I +AY+HS HRDLK EN++ DE +K+IDFG NK+ GS
Sbjct: 116 IVSAVAYVHSQGYAHRDLKPENLLFDE-YHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAY 174
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTK 231
APE+ Q Y G+ D+WS+GI+++ F++ N A KI + Y
Sbjct: 175 AAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMR------GKYDV 228
Query: 232 NPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHN 271
SI L ++L VD K+R+S+++++N + +++N
Sbjct: 229 PKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYN 268
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 81.6 bits (200), Expect = 1e-15
Identities = 63/217 (29%), Positives = 105/217 (48%), Gaps = 9/217 (4%)
Query: 55 HHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSY-TVLYLMKMSMLPTFEE 111
H +E KE EL + L+HK +++ + K I Y S ++ +++K + T E
Sbjct: 122 HQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPE 181
Query: 112 RALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGI 171
+ QI G+ YLH I+HRDLKL N ++E++ +K+ DFG A + P + I
Sbjct: 182 VRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAM-ELKVGDFGLAARLEPLEHRRRTI 240
Query: 172 RGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAK--IDDVAFEAY 229
G+ ++PEV + + G D+W+LG +M+ +P F K + Y
Sbjct: 241 CGTPNYLSPEVLNK-QGHGCESDIWALGCVMYTML--LGRPPFETTNLKETYRCIREARY 297
Query: 230 TKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFF 266
T + L + L +LS + + R S+ D+I FF
Sbjct: 298 TMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF 334
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 81.6 bits (200), Expect = 1e-15
Identities = 72/242 (29%), Positives = 118/242 (48%), Gaps = 11/242 (4%)
Query: 25 QGTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVK-EYELLKKLNHKCIIEALDC-- 81
+GT +V+ +S G +A+K R + + + ++ E E++ LNH II +
Sbjct: 61 KGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFE 120
Query: 82 NKRKHTITFPYYSYTVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLE 139
N K I Y S LY + + L E R +F QI + Y H + +VHRDLKLE
Sbjct: 121 NSSKIVIVMEYASRGDLYDYISERQQLSEREARH-FFRQIVSAVHYCHQNRVVHRDLKLE 179
Query: 140 NIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLG 199
NI++D + NIKI DFG + ++ + GS +PE+ Y G VD WSLG
Sbjct: 180 NILLDAN-GNIKIADFGLS-NLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLG 237
Query: 200 IMMFEFFNNSNK-PAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQ 258
++++ + + KI + ++ AY + P + + L LL V+ +R +++
Sbjct: 238 VLLYILVHGTMPFDGHDHKIL-VKQISNGAY-REPPKPSDACGLIRWLLMVNPTRRATLE 295
Query: 259 DV 260
DV
Sbjct: 296 DV 297
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 80.9 bits (198), Expect = 2e-15
Identities = 54/160 (33%), Positives = 88/160 (54%), Gaps = 11/160 (6%)
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
QI EG+ Y+H+ +IVHRDLK ENI++DE+ N+KI DFG A + E + G+
Sbjct: 136 QIFEGVEYIHAKSIVHRDLKPENILLDEN-HNVKITDFGFAKQL-QEGEKLTNLCGTPGY 193
Query: 178 MAPEVFQRLKYEGTP-----VDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYT-K 231
+APE + +EG+P VD+W+ G++MF ++ + ++ Y+
Sbjct: 194 LAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFT 253
Query: 232 NPTTLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+P +IS DL K L VD QR+++++V+ FF +
Sbjct: 254 SPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQ 293
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 80.5 bits (197), Expect = 3e-15
Identities = 73/226 (32%), Positives = 106/226 (46%), Gaps = 30/226 (13%)
Query: 63 EYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSML-------PTFEERA-- 113
E E+LKKLNH CII K K+ Y Y VL LM+ L +E
Sbjct: 273 EIEILKKLNHPCII------KIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCK 325
Query: 114 LWFCQICEGIAYLHSHNIVHRDLKLENIMV--DESLCNIKIIDFGSAVDVGPNKEACHGI 171
L+F Q+ + YLH + I+HRDLK EN+++ E C IKI DFG + +G +
Sbjct: 326 LYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILG-ETSLMRTL 384
Query: 172 RGSEQLMAPEVFQRLKYEG--TPVDMWSLGIMMFEFFNNSNKPAFP---WKIAKIDDVAF 226
G+ +APEV + G VD WSLG+++F S P F +++ D +
Sbjct: 385 CGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICL--SGYPPFSEHRTQVSLKDQITS 442
Query: 227 EAYTKNP----TTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
Y P ++DL KLL VD K R + ++ + + Q+
Sbjct: 443 GKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 80.5 bits (197), Expect = 3e-15
Identities = 61/187 (32%), Positives = 96/187 (50%), Gaps = 11/187 (5%)
Query: 35 SKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPY 92
++ G +ALKK R ++E LLK+L H I+ LD N+RK + F +
Sbjct: 23 NRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEF 82
Query: 93 YSYTVLYLMKM---SMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN 149
S + M S LP ++ F Q+ +G+++ HSH ++HRDLK +N++++E L
Sbjct: 83 LSQDLKKYMDSTPGSELPLHLIKSYLF-QLLQGVSFCHSHRVIHRDLKPQNLLINE-LGA 140
Query: 150 IKIIDFGSAVDVG-PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNN 208
IK+ DFG A G P + H + + APE+ K+ T VD+WS+G + E
Sbjct: 141 IKLADFGLARAFGVPLRTYTHEV-VTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMV-- 197
Query: 209 SNKPAFP 215
+ K FP
Sbjct: 198 TRKALFP 204
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 80.5 bits (197), Expect = 3e-15
Identities = 77/306 (25%), Positives = 125/306 (40%), Gaps = 47/306 (15%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK 85
G+ C + K G K+A+KK + +E LLK + H+ +I LD
Sbjct: 37 GSVCSA--IDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPA 94
Query: 86 HTITFPYYSYTVLYLMKMSMLPT----FEERALWFC--QICEGIAYLHSHNIVHRDLKLE 139
++ Y Y V+ M+ + F E + + Q+ +G+ Y+HS +VHRDLK
Sbjct: 95 SSLRNFYDFYLVMPFMQTDLQKIMGMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPG 154
Query: 140 NIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLG 199
N+ V+E C +KI+DFG A G + APEV + VD+WS+G
Sbjct: 155 NLAVNED-CELKILDFGLARHADAEMT---GYVVTRWYRAPEVILSWMHYNQTVDIWSVG 210
Query: 200 IMMFEFFNNSNKPAFPWK--------------------IAKIDDVAFEAYTKN------- 232
+M E + K F K + K++D A ++Y ++
Sbjct: 211 CIMAEML--TGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRK 268
Query: 233 ------PTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHARTKRIL 286
P + DL K+L +DV +RL+ + FF+ + + A L
Sbjct: 269 DFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSL 328
Query: 287 ERSQTT 292
E + T
Sbjct: 329 EHEKLT 334
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 80.1 bits (196), Expect = 3e-15
Identities = 65/222 (29%), Positives = 111/222 (49%), Gaps = 25/222 (11%)
Query: 61 VKEYELLKKLNHKCIIEALDC---NKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFC 117
+ E ++ K ++H I++ +DC + + + + +++ L+K + T E +
Sbjct: 127 LSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTT 186
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
QIC I Y+HS ++HRDLKL NI D + N+KI DFG A + E + I G+
Sbjct: 187 QICGAIKYMHSRRVIHRDLKLGNIFFDSNY-NLKIGDFGLAAVLANESERKYTICGTPNY 245
Query: 178 MAPEVFQRLKYEG--TPVDMWSLGIMMFEFFNNSNKPAFP-------WKIAKIDDVAFEA 228
+APEV K+ G VD+WSLG+M++ KP F ++ K D +F
Sbjct: 246 IAPEVLMG-KHSGHSFEVDIWSLGVMLYALL--IGKPPFQARDVNTIYERIKCRDFSF-- 300
Query: 229 YTKNPTTLNISID---LCMKLLSVDVKQRLSIQDVINDSFFQ 267
P IS + L +LS+D +R S+ ++++ +F+
Sbjct: 301 ----PRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFR 338
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/248 (29%), Positives = 113/248 (45%), Gaps = 36/248 (14%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVK-EYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTV 97
G K+A+K + N E V+ E ++L+ H II + + I Y V
Sbjct: 43 GHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDI------YVV 96
Query: 98 LYLMKMSMLPTF---------EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC 148
+ +K L + +E +F QI G+ Y H + +VHRDLK EN+++D S C
Sbjct: 97 MEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLD-SRC 155
Query: 149 NIKIIDFGSAVDVGPN---KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF 205
NIKI DFG + + K +C GS APEV Y G VD+WS G++++
Sbjct: 156 NIKIADFGLSNVMRDGHFLKTSC----GSPNYAAPEVISGKLYAGPEVDVWSCGVILYAL 211
Query: 206 ------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQD 259
F++ N P KI YT + + DL ++L VD +R++I +
Sbjct: 212 LCGTLPFDDENIPNLFKKIKG------GIYTLPSHLSSEARDLIPRMLIVDPVKRITIPE 265
Query: 260 VINDSFFQ 267
+ +FQ
Sbjct: 266 IRQHRWFQ 273
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 79.7 bits (195), Expect = 5e-15
Identities = 55/177 (31%), Positives = 94/177 (53%), Gaps = 17/177 (9%)
Query: 97 VLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG 156
+L L ++S+L E F QI + Y HS + VHRDLKLENI++D++ N K+ DFG
Sbjct: 123 LLSLRRISLLECGE----LFAQISGAVYYAHSMHCVHRDLKLENILLDKN-GNAKLTDFG 177
Query: 157 SAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSN 210
+ K + G+ MAPE+ +R Y+G +D+WSLG++++ F++ +
Sbjct: 178 FTREC-MTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDD 236
Query: 211 KPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+ WKI ++ ++A + + DL +LL+ + +R S+ V+ F Q
Sbjct: 237 EAKTKWKIVN-EEPKYDA----KVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQ 288
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 79.7 bits (195), Expect = 5e-15
Identities = 69/223 (30%), Positives = 109/223 (47%), Gaps = 23/223 (10%)
Query: 61 VKEYELLKKLNHKCIIEALD-CNKRKHT-ITFPYYSYTVL--YLMKMSMLPTFEERALWF 116
V+E L + L H I + C H + F Y S L Y+++ L E A F
Sbjct: 171 VREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLK--EHHARKF 228
Query: 117 CQ-ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSE 175
+ I + YLH++NIVHRDLK+ENIM+ S IKIIDFG + ++ ++ H GS
Sbjct: 229 ARGIASALQYLHANNIVHRDLKIENIMISSS-GEIKIIDFGLS-NIFDYRKQLHTFCGSL 286
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAY 229
APE+ + Y G VD+WS GI+++ F++ N KI K
Sbjct: 287 YFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKK-------GK 339
Query: 230 TKNPTTLNIS-IDLCMKLLSVDVKQRLSIQDVINDSFFQENHN 271
P+ L+I I L +++ VD +R ++++V+ + ++
Sbjct: 340 VDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYD 382
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 79.7 bits (195), Expect = 5e-15
Identities = 59/215 (27%), Positives = 101/215 (46%), Gaps = 11/215 (5%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTI--TFPYYSYTVLYLMKMSMLPTFEERAL-WFCQ 118
+E ++K LNH ++ D + + Y L+ + + P E A+ +F Q
Sbjct: 80 REIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQ 139
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLM 178
I G++Y H+ IVHRDLK EN+++D NIKI DFG A + + GS
Sbjct: 140 IIIGVSYCHALGIVHRDLKPENLLLDHKY-NIKIADFGMAA-LETEGKLLETSCGSPHYA 197
Query: 179 APEVFQRLKYEGTPVDMWSLGIMMFEFFN-----NSNKPAFPWKIAKIDDVAFEAYTKNP 233
APE+ + Y+G D+WS G+++F + + K+ FE + +
Sbjct: 198 APEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDE 257
Query: 234 TTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+ DL K+L+VD ++R+ +D++ Q+
Sbjct: 258 ISREAQ-DLIRKILTVDPERRIKTRDILKHPLLQK 291
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 79.7 bits (195), Expect = 5e-15
Identities = 59/176 (33%), Positives = 90/176 (50%), Gaps = 9/176 (5%)
Query: 101 MKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAV 159
+K + P E A F QI G+ YLHSH I+HRDL L N+++ ++ NIKI DFG A
Sbjct: 101 LKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNM-NIKIADFGLAT 159
Query: 160 DVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIA 219
+ E + + G+ ++PE+ R + G D+WSLG M + +P F
Sbjct: 160 QLKMPHEKHYTLCGTPNYISPEIATRSAH-GLESDVWSLGCMFYTLL--IGRPPFDTDTV 216
Query: 220 K--IDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRLSIQDVINDSFFQENHNS 272
K ++ V Y + PT L+I DL +LL + RLS+ V++ F N ++
Sbjct: 217 KNTLNKVVLADY-EMPTFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSST 271
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 79.7 bits (195), Expect = 5e-15
Identities = 59/176 (33%), Positives = 90/176 (50%), Gaps = 9/176 (5%)
Query: 101 MKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAV 159
+K + P E A F QI G+ YLHSH I+HRDL L N+++ ++ NIKI DFG A
Sbjct: 101 LKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNM-NIKIADFGLAT 159
Query: 160 DVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIA 219
+ E + + G+ ++PE+ R + G D+WSLG M + +P F
Sbjct: 160 QLKMPHEKHYTLCGTPNYISPEIATRSAH-GLESDVWSLGCMFYTLL--IGRPPFDTDTV 216
Query: 220 K--IDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRLSIQDVINDSFFQENHNS 272
K ++ V Y + PT L+I DL +LL + RLS+ V++ F N ++
Sbjct: 217 KNTLNKVVLADY-EMPTFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSST 271
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 79.3 bits (194), Expect = 6e-15
Identities = 59/208 (28%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 62 KEYELLKKLNHKCIIEALDCNKR-KHTITFPYYSYTVLY--LMKMSMLPTFEERALWFCQ 118
+E E+++ L H I+ LD + K + Y+ L+ L LP + +A+ Q
Sbjct: 50 REIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAI-AAQ 108
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLM 178
+ + YLHSH I+HRD+K +NI++ + IK+ DFG A + N I+G+ M
Sbjct: 109 LVSALYYLHSHRILHRDMKPQNILLAKG-GGIKLCDFGFARAMSTNTMVLTSIKGTPLYM 167
Query: 179 APEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNI 238
+PE+ + Y+ T D+WS+G +++E + P + I ++ + + + P+T++
Sbjct: 168 SPELVEERPYDHT-ADLWSVGCILYELAVGT-PPFYATSIFQLVSLILKDPVRWPSTISP 225
Query: 239 SI-DLCMKLLSVDVKQRLSIQDVINDSF 265
+ LL+ D +QRLS D++ F
Sbjct: 226 CFKNFLQGLLTKDPRQRLSWPDLLYHPF 253
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 79.3 bits (194), Expect = 6e-15
Identities = 58/192 (30%), Positives = 98/192 (50%), Gaps = 15/192 (7%)
Query: 88 ITFPYYSYTVLYLMKMSMLPTFE-ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDES 146
+ F Y LY + +S P E E +F Q+ I Y+H +++VHRDLK+ENI++DE+
Sbjct: 139 LIFEYVKGRQLYDIIISSGPLKEKEGQRYFRQLLSAIDYIHRNSVVHRDLKIENILIDEN 198
Query: 147 LCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF- 205
N+K+IDFG + + NK + GS APE+ Q +Y G +D+WSLG++++
Sbjct: 199 -DNVKLIDFGLS-NFYDNKTLLNTFCGSLYFAAPELLQGQRYCGPEIDVWSLGVVLYAIL 256
Query: 206 -----FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDV 260
F++ + AKI D F+ + K T +++L ++ R+ + V
Sbjct: 257 CGCVPFDDEDVQGLQ---AKIMDADFK-FCK--TISREAMELIRGMIVAQPSSRMGLSQV 310
Query: 261 INDSFFQENHNS 272
I + + S
Sbjct: 311 IGSEWVNKGQKS 322
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 79.3 bits (194), Expect = 6e-15
Identities = 64/259 (24%), Positives = 122/259 (46%), Gaps = 16/259 (6%)
Query: 25 QGTTCEVEIVSKSD-GSKLALKKF-RSWDLHNHHKEVCVKEYELLKKLNHKCIIEALD-- 80
+GT +V+ ++ G +A+K RS + + +E ++K + H C++ +
Sbjct: 17 EGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCVVRLYEVL 76
Query: 81 CNKRKHTITFPYYSYTVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKL 138
++ K I Y + L+ +++ L E R +F Q+ +G+ Y HS + HRDLK
Sbjct: 77 ASRTKIYIILEYITGGELFDKIVRNGRLSESEARK-YFHQLIDGVDYCHSKGVYHRDLKP 135
Query: 139 ENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSL 198
EN+++D S N+KI DFG + G+ +APEV Y G D+WS
Sbjct: 136 ENLLLD-SQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAVADIWSC 194
Query: 199 GIMMFEF---FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQR 254
G++++ + ++ P +KID F P+ + L ++L + + R
Sbjct: 195 GVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSC----PSYFALGAKSLINRILDPNPETR 250
Query: 255 LSIQDVINDSFFQENHNSV 273
++I ++ D +F +++ V
Sbjct: 251 ITIAEIRKDEWFLKDYTPV 269
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 79.3 bits (194), Expect = 6e-15
Identities = 55/168 (32%), Positives = 86/168 (50%), Gaps = 7/168 (4%)
Query: 40 SKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF--PYYSYTV 97
+++A+K L + + +E E++K+L H II+ + K+ I Y S
Sbjct: 165 NEVAIKIIDKSQLDQTNLQKVYREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGE 224
Query: 98 L--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDF 155
+ Y+ K + R F QI + Y H IVHRDLK EN+++D ++ NIKI DF
Sbjct: 225 IFDYIAKYGRMSESAAR-FKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNM-NIKIADF 282
Query: 156 GSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
G + P E GS APEVF+ +Y G +D+WSLG++++
Sbjct: 283 GFSNHFKPG-ELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLY 329
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 79.0 bits (193), Expect = 8e-15
Identities = 63/229 (27%), Positives = 111/229 (47%), Gaps = 13/229 (5%)
Query: 40 SKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHT--ITFPYYSYTV 97
+K+A+K L + +E +++K ++H I+++ + + + I Y S
Sbjct: 40 TKVAIKSIDVSALDRENLIKLEREVKIVKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGE 99
Query: 98 LYLMKMSMLPTFEERAL-WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG 156
LY + E A WF + +AYLHS IVHRDLK ENI++ ++ NIKIIDFG
Sbjct: 100 LYETLIEKGRVAENVARKWFSETASAVAYLHSQGIVHRDLKAENILLGKN-SNIKIIDFG 158
Query: 157 SAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPW 216
+ + + + GS APE+ Y+G D+WS+G++++ FP+
Sbjct: 159 FS-NFQTGDQLLNTWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYILVAG----GFPF 213
Query: 217 ---KIAKIDDVAFEAYTKNPTTLNIS-IDLCMKLLSVDVKQRLSIQDVI 261
+ K+ K P +++ D K+L ++ +R +IQ+V+
Sbjct: 214 PSDSVNKLKRSVLSGLVKIPYWVSVECADFIRKMLVLNPGKRYTIQNVL 262
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 79.0 bits (193), Expect = 8e-15
Identities = 61/220 (27%), Positives = 107/220 (47%), Gaps = 17/220 (7%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITFPY-YSYTVLYLMKMSMLPTFEERAL-WFCQI 119
+E ++ +L H I+ + K I F ++ K+S E+ + +F Q+
Sbjct: 69 REIAIMHRLRHPSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGRFCEDLSRRYFQQL 128
Query: 120 CEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG--SAVDVGPNKEACHGIRGSEQL 177
+ Y HS I HRDLK EN+++DE L ++KI DFG + D H + G+
Sbjct: 129 ISAVGYCHSRGIFHRDLKPENLLLDEKL-DLKISDFGLSALTDQIRPDGLLHTLCGTPAY 187
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTK 231
+APEV + Y+G +D+WS GI++F FN+ N KI K + +T
Sbjct: 188 VAPEVLAKKGYDGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYK-GEFRIPKWTS 246
Query: 232 NPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHN 271
L +LL + + R++I+++I+D +F++ ++
Sbjct: 247 PDLR-----RLLTRLLDTNPQTRITIEEIIHDPWFKQGYD 281
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 79.0 bits (193), Expect = 8e-15
Identities = 66/224 (29%), Positives = 116/224 (51%), Gaps = 21/224 (9%)
Query: 38 DGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKR--KHTITFPYYSY 95
DG+++A+K+ L+ +E + E +L+++NH II +D K K + Y
Sbjct: 34 DGTEVAIKEIAMDRLNKKLQESLMSEIFILRRINHPNIIRLIDMIKSPGKVHLVLEYCKG 93
Query: 96 TVL--YLMKMSMLPTFEERALWFCQ-ICEGIAYLHSHNIVHRDLKLENIMV--DESLCNI 150
L Y+ + ++P E A F Q + G+ L +NI+HRDLK +N+++ +E+ ++
Sbjct: 94 GDLSVYVQRHGIVP--EATAKHFMQQLAAGLQVLRDNNIIHRDLKPQNLLLSTNENDADL 151
Query: 151 KIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF----- 205
KI DFG A + P + + GS MAPE+ Q KY+ D+WS+G ++F+
Sbjct: 152 KIADFGFARSLQP-RGLAETLCGSPLYMAPEIMQLQKYD-AKADLWSVGAILFQLVTGRT 209
Query: 206 -FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNIS-IDLCMKLL 247
F +++ I + ++ F ++ L++ IDLC KLL
Sbjct: 210 PFTGNSQIQLLQNIIRSTELHFPGDCRD---LSLDCIDLCQKLL 250
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 78.6 bits (192), Expect = 1e-14
Identities = 61/228 (26%), Positives = 106/228 (45%), Gaps = 15/228 (6%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCII---EALDCNKRKH-TITFPYYSYT 96
K+A+K + +++ +E + ++++NH I+ E ++ R H I +
Sbjct: 74 KVAVKIMDKAKMDAKAQKLLSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGGEL 133
Query: 97 VLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG 156
Y+ + L + + L F QI ++++HS NIVHRD+K EN+M S +K++DFG
Sbjct: 134 YTYVHERGKLTEGDAKPL-FAQIVSAVSHMHSRNIVHRDIKAENVMF-SSPNTVKLVDFG 191
Query: 157 SAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPW 216
+ V ++ GS APE+FQ Y G VD+W+LG+++F P+
Sbjct: 192 FSCLV-DREQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFMLIG----VTPF 246
Query: 217 KIAKIDD----VAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDV 260
K + D + Y ++ +L +L D QR I V
Sbjct: 247 KAETVPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSV 294
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 78.6 bits (192), Expect = 1e-14
Identities = 74/249 (29%), Positives = 113/249 (44%), Gaps = 38/249 (15%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVK-EYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTV 97
G K+A+K + N E V+ E ++L+ H II + I P Y V
Sbjct: 42 GHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRLYE------VIETPTDIYLV 95
Query: 98 L----------YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESL 147
+ Y+++ L E R +F QI G+ Y H + +VHRDLK EN+++D S
Sbjct: 96 MEYVNSGELFDYIVEKGRLQEDEARN-FFQQIISGVEYCHRNMVVHRDLKPENLLLD-SK 153
Query: 148 CNIKIIDFGSAVDVGPN---KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
CN+KI DFG + + K +C GS APEV Y G VD+WS G++++
Sbjct: 154 CNVKIADFGLSNIMRDGHFLKTSC----GSPNYAAPEVISGKLYAGPEVDVWSCGVILYA 209
Query: 205 F------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQ 258
F++ N P KI YT + DL ++L VD +R++I
Sbjct: 210 LLCGTLPFDDENIPNLFKKIKG------GIYTLPSHLSPGARDLIPRMLVVDPMKRVTIP 263
Query: 259 DVINDSFFQ 267
++ +FQ
Sbjct: 264 EIRQHPWFQ 272
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 78.2 bits (191), Expect = 1e-14
Identities = 69/224 (30%), Positives = 103/224 (45%), Gaps = 32/224 (14%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL---------YLMKMSMLPTFEER 112
+E LK L H II+ D IT P V+ Y+++ + T +E
Sbjct: 81 REISYLKLLRHPHIIKLYD------VITTPTDIVMVIEYAGGELFDYIVEKKRM-TEDEG 133
Query: 113 ALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA---VDVGPNKEACH 169
+F QI I Y H H IVHRDLK EN+++D++L N+KI DFG + D K +C
Sbjct: 134 RRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNL-NVKIADFGLSNIMTDGNFLKTSC- 191
Query: 170 GIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS---NKPAFPWKIAKIDDVAF 226
GS APEV Y G VD+WS GI+++ + P K++ +
Sbjct: 192 ---GSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVY 248
Query: 227 EAYTKNPTTLNISI-DLCMKLLSVDVKQRLSIQDVINDSFFQEN 269
P L+ L +++ D QR++IQ++ D +F N
Sbjct: 249 VM----PDFLSPGAQSLIRRMIVADPMQRITIQEIRRDPWFNVN 288
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 78.2 bits (191), Expect = 1e-14
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 36/249 (14%)
Query: 39 GSKLALK-----KFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYY 93
G K+A+K K RS D+ K +E + LK H II K I+ P
Sbjct: 39 GHKVAVKILNRQKIRSLDVVGKIK----REIQNLKLFRHPHII------KLYQVISTPTD 88
Query: 94 SYTVL----------YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMV 143
+ V+ Y+ K + E R L F QI + Y H H +VHRDLK EN+++
Sbjct: 89 FFMVMEYVSGGELFDYICKHGRVEEMEARRL-FQQILSAVDYCHRHMVVHRDLKPENVLL 147
Query: 144 DESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
D + N KI DFG + ++ + E GS APEV Y G VD+WS G++++
Sbjct: 148 DAHM-NAKIADFGLS-NMMSDGEFLRTSCGSPNYTAPEVISGRLYAGPEVDIWSCGVILY 205
Query: 204 EFFNNS---NKPAFPWKIAKIDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRLSIQD 259
+ + P KI F P LN S+ L M +L VD +R +I+D
Sbjct: 206 ALLCGTLPFDDEHVPTLFKKIRGGVFYI----PEYLNRSVATLLMHMLQVDPLKRATIKD 261
Query: 260 VINDSFFQE 268
+ +F++
Sbjct: 262 IREHEWFKQ 270
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 78.2 bits (191), Expect = 1e-14
Identities = 75/270 (27%), Positives = 120/270 (43%), Gaps = 37/270 (13%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G K+A+K L +E +LK + H +++ D + K Y Y VL
Sbjct: 74 GQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKK------YLYLVL 127
Query: 99 ----------YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC 148
YL+K L E R +F QI + + HS++I HRDLK EN+++DE
Sbjct: 128 EHVSGGELFDYLVKKGRLTPKEARK-FFRQIVSALDFCHSYSICHRDLKPENLLLDEK-N 185
Query: 149 NIKIIDFGSA-VDVGPN--KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF 205
NI+I DFG A + VG + + +C GS PEV + KY+G DMWS G+++F
Sbjct: 186 NIRIADFGMASLQVGDSLLETSC----GSPHYACPEVIKGEKYDGRRADMWSCGVILFAL 241
Query: 206 ------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQD 259
F++ N + K+ F P L ++ V+ ++RLS++
Sbjct: 242 LVGALPFDDDNLRQL---LEKVKRGVFHMPHFIPPDCQ---SLLRGMIEVEPEKRLSLEQ 295
Query: 260 VINDSFFQENHNSVDGVSAHARTKRILERS 289
+ ++ + D A +R+ RS
Sbjct: 296 IQKHPWYLGGKHEPDPCLEPAPGRRVAMRS 325
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/175 (32%), Positives = 87/175 (49%), Gaps = 7/175 (4%)
Query: 35 SKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPY 92
+K G +ALKK R ++E LLK+LNH I++ LD + K + F +
Sbjct: 23 NKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEF 82
Query: 93 YSYTVLYLMKMSMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNI 150
+ M S L + + Q+ +G+A+ HSH ++HRDLK +N++++ I
Sbjct: 83 LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA-I 141
Query: 151 KIIDFGSAVDVG-PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
K+ DFG A G P + H + + APE+ KY T VD+WSLG + E
Sbjct: 142 KLADFGLARAFGVPVRTYTHEV-VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAE 195
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 78.2 bits (191), Expect = 1e-14
Identities = 63/223 (28%), Positives = 112/223 (49%), Gaps = 19/223 (8%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITF--PYYSYTVLYLMKMSMLPTFEERAL-WFCQ 118
+E +L+++ H I++ + K I F Y L+ K++ EE A +F Q
Sbjct: 75 REISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELF-NKVAKGRLKEEMARKYFQQ 133
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG-SAVDVGPNKEAC-HGIRGSEQ 176
+ +++ H + HRDLK EN+++DE+ N+K+ DFG SAV ++ H G+
Sbjct: 134 LISAVSFCHFRGVYHRDLKPENLLLDEN-GNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA 192
Query: 177 LMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYT 230
+APEV R Y+G VD+WS G+++F F++ N A KI + D F
Sbjct: 193 YVAPEVLARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGD---FRCPR 249
Query: 231 KNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSV 273
P +N L +++L ++R ++ D++ S+F++ +
Sbjct: 250 WFPVEIN---RLLIRMLETKPERRFTMPDIMETSWFKKGFKHI 289
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 78.2 bits (191), Expect = 1e-14
Identities = 65/266 (24%), Positives = 126/266 (46%), Gaps = 24/266 (9%)
Query: 38 DGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK---HTITFPYYS 94
+G +A+K+ ++ ++E +LLK LNHK I++ L +K K H I +
Sbjct: 42 NGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLGSSKTKTHLHIILEYVEN 101
Query: 95 YTVLYLMKMSMLPTFEER--ALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESLCNIK 151
++ ++K + F E A++ Q+ EG+ YLH ++HRD+K NI+ E L +K
Sbjct: 102 GSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL--VK 159
Query: 152 IIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE------- 204
+ DFG A + H + G+ MAPEV + + D+WS+G + E
Sbjct: 160 LADFGVATKLNEADVNTHSVVGTPYWMAPEVIE-MSGVCAASDIWSVGCTVIELLTCVPP 218
Query: 205 FFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRLSIQDVIND 263
+++ PA ++I + D+ P +L+ I D + D +QR + +++
Sbjct: 219 YYDLQPMPAL-FRIVQDDNPPI------PDSLSPDITDFLRQCFKKDSRQRPDAKTLLSH 271
Query: 264 SFFQENHNSVDGVSAHARTKRILERS 289
+ + + ++ H+ T + ++ +
Sbjct: 272 PWIRNSRRALQSSLRHSGTIKYMKEA 297
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 77.8 bits (190), Expect = 2e-14
Identities = 58/180 (32%), Positives = 87/180 (48%), Gaps = 12/180 (6%)
Query: 96 TVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDF 155
++L L K T E + QI G YLH + ++HRDLKL N+ ++E L +KI DF
Sbjct: 137 SLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDL-EVKIGDF 195
Query: 156 GSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFP 215
G A V + E + G+ +APEV + K VD+WS+G +M+ KP F
Sbjct: 196 GLATKVEYDGERKKTLCGTPNYIAPEVLSK-KGHSFEVDVWSIGCIMYTLL--VGKPPFE 252
Query: 216 WKIAKIDDVAFEAYTKN----PTTLN-ISIDLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
K + KN P +N ++ L K+L D R +I +++ND FF +
Sbjct: 253 TSCLK---ETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGY 309
>ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 300
Score = 77.8 bits (190), Expect = 2e-14
Identities = 53/162 (32%), Positives = 83/162 (50%), Gaps = 15/162 (9%)
Query: 56 HKEVCVKEYELLKKLNHKCIIEALDCNKRKH--TITFPYYSYTVLYLMKMSMLPTFEERA 113
++ KE E+L ++H+ ++ LD K +I Y +Y L+ M ++ A
Sbjct: 55 YRRYAEKEVEMLSSISHRRVVRLLDFFPTKSGLSIILEYLNYGSLHEMIEYLMENGYRVA 114
Query: 114 ---LW--FCQICEGIAYLHSHNIVHRDLKLENIMVD------ESLCNIKIIDFGSAVDVG 162
+W Q +G+ YLHS I+HRD+K NI+++ E L K+ DF A ++
Sbjct: 115 GDLVWSVLAQAADGLRYLHSKQIIHRDVKPSNILMNRTLVQKEELLEFKLCDFSLAKNLC 174
Query: 163 PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
+ C GI G+ MAPEV +Y T VD+WSLGI ++E
Sbjct: 175 GKESVC-GIVGTPSYMAPEVVSGERY-STSVDIWSLGISIYE 214
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 77.8 bits (190), Expect = 2e-14
Identities = 55/172 (31%), Positives = 88/172 (50%), Gaps = 13/172 (7%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYT 96
G K+A+K L + +E ++K + H ++ D NK+ + + S
Sbjct: 70 GRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGG 129
Query: 97 VL--YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
L YL++ L + E R +F QI + + H+HNI HRDLK EN+++DE NIK+ D
Sbjct: 130 ELFDYLVRKGRLMSKEARK-FFRQIISALDFCHAHNICHRDLKPENLLLDER-NNIKVAD 187
Query: 155 FGSA---VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
FG A V+ + +C GS PEV + KY+G D+WS G++++
Sbjct: 188 FGMASLQVEGSMLETSC----GSPHYACPEVIRGEKYDGRKADVWSCGVILY 235
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 77.8 bits (190), Expect = 2e-14
Identities = 59/223 (26%), Positives = 102/223 (45%), Gaps = 19/223 (8%)
Query: 62 KEYELLKKLNHKCIIEALD--CNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFCQI 119
+E +L+++ H I+ L+ K K I Y LY +F Q+
Sbjct: 104 REISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARGRLREGTARRYFQQL 163
Query: 120 CEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKE--ACHGIRGSEQL 177
+A+ HS + HRDLKLEN+++D+ N+K+ DFG +V K+ C G+
Sbjct: 164 ISSVAFCHSRGVYHRDLKLENLLLDDK-GNVKVSDFGLSVVSEQLKQEGICQTFCGTPAY 222
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTK 231
+APEV R YEG D+WS G+++F F++ N KI ++ K
Sbjct: 223 LAPEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKI-------YKGQFK 275
Query: 232 NPTTLNISI-DLCMKLLSVDVKQRLSIQDVINDSFFQENHNSV 273
P + + L ++L + R++I +++ +F++ V
Sbjct: 276 CPKWFSPELARLVTRMLDTNPDTRITIPEIMKHRWFKKGFKHV 318
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/175 (32%), Positives = 83/175 (47%), Gaps = 19/175 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G K+A+K L +E ++K ++H ++ D + K Y Y +L
Sbjct: 41 GKKVAIKIINREKLSESVLMKVEREIAIMKLIDHPHVLGLSDVYENKK------YLYLIL 94
Query: 99 ----------YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC 148
YL+K L E R +F QI + + HSH+I HRDLK EN+++DE
Sbjct: 95 EHVSGGELFDYLVKKGRLTPKEARK-FFRQIISALDFCHSHSICHRDLKPENLLLDEK-N 152
Query: 149 NIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
NIKI DFG A + P GS PEV + KY+G D+WS G++++
Sbjct: 153 NIKIADFGMA-SLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILY 206
>YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 842
Score = 77.4 bits (189), Expect = 2e-14
Identities = 65/249 (26%), Positives = 116/249 (46%), Gaps = 32/249 (12%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G K+A+K+ KE+ V E ++K HK I+ L+ R + V+
Sbjct: 588 GDKVAIKQMVL--SKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDL-----WVVM 640
Query: 99 YLMKMSML---------------PTFEERALWFC-QICEGIAYLHSHNIVHRDLKLENIM 142
M+ L P E + + + C+G+ +LH +I+HRD+K +N++
Sbjct: 641 EFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVL 700
Query: 143 VDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMM 202
+D + +KI DFG + + + G+ MAPEV ++ +Y+ +D+WSLGIM
Sbjct: 701 LD-TRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYD-EKIDVWSLGIMT 758
Query: 203 FEFFNNSNKPAF----PWKIAKIDDVAFEAYTKNPTTLNISIDLCMKL-LSVDVKQRLSI 257
E +P + P K + K+P +L++ I + + L VDV+ R S
Sbjct: 759 IEML--EGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRAST 816
Query: 258 QDVINDSFF 266
+++++ FF
Sbjct: 817 EELLHHGFF 825
>Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 77.4 bits (189), Expect = 2e-14
Identities = 63/185 (34%), Positives = 96/185 (51%), Gaps = 34/185 (18%)
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKII--DFGSA-VDVGPNKEACHGIRGS 174
Q+ E +AYLHS IVHR+LKLEN++ L N KI+ DF A ++ G KE C G+
Sbjct: 128 QVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPC----GT 183
Query: 175 EQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKN-- 232
+ +APEV R +Y G PVD W++G++M+ S P F ++++ +E + KN
Sbjct: 184 PEYLAPEVVGRQRY-GRPVDCWAIGVIMYILL--SGNPPF---YEEVEEDDYENHDKNLF 237
Query: 233 ------------PTTLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFFQEN----HNSV 273
P +IS DL +L+ V+ QR++ ++ I+ + N N
Sbjct: 238 RKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIK 297
Query: 274 DGVSA 278
DGV A
Sbjct: 298 DGVCA 302
>Hs19923134 [T] KOG4250 TANK binding protein kinase TBK1
Length = 745
Score = 77.0 bits (188), Expect = 3e-14
Identities = 61/177 (34%), Positives = 88/177 (49%), Gaps = 16/177 (9%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLY- 99
K+A+K R +L ++E E +++KKLNH +++A D + + + + Y
Sbjct: 40 KIAIKSCRL-ELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYC 98
Query: 100 ----LMKMSMLPTF-----EERAL-WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN 149
L K+ P E + L I GI YLH + I+HRDLK ENI++ +
Sbjct: 99 SGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGK 158
Query: 150 I--KIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
I KIID G A DV C G+ Q +APE+F+ Y T VD WS G M+FE
Sbjct: 159 IIHKIIDLGYAKDVDQG-SLCTSFVGTLQYLAPELFENKPYTAT-VDYWSFGTMVFE 213
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 77.0 bits (188), Expect = 3e-14
Identities = 69/258 (26%), Positives = 114/258 (43%), Gaps = 45/258 (17%)
Query: 45 KKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY-YSYTVLYLMKM 103
KK+ SWD + + ++E + L+++NH I++ + + + F + Y LY +
Sbjct: 3 KKYYSWD-----ECINLREVKSLRRMNHPNIVKLKEVIRENDILYFVFEYMECNLYQLMK 57
Query: 104 SMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDV 161
F E + W Q+ +G++Y+H HRDLK EN++V + + IKI DFG A +V
Sbjct: 58 DRQKLFAEADIKNWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKDI--IKIADFGLAREV 115
Query: 162 GPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFP------ 215
+ + + APEV + + VDMW++G +M E S +P FP
Sbjct: 116 NSSPPFTEYV-STRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELL--SLRPIFPGASEAD 172
Query: 216 --WKIAKIDDVAFE---------AYTKN---------------PTTLNISIDLCMKLLSV 249
+KI + E A T N P+ +I+L +L S
Sbjct: 173 EIYKICSVIGTPTEETWLEGLNLANTINYQFPQLPGVPLSSLMPSASEDAINLIERLCSW 232
Query: 250 DVKQRLSIQDVINDSFFQ 267
D R + +V+ FFQ
Sbjct: 233 DPSSRPTAAEVLQHPFFQ 250
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 76.6 bits (187), Expect = 4e-14
Identities = 55/168 (32%), Positives = 82/168 (48%), Gaps = 12/168 (7%)
Query: 108 TFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEA 167
T E + QI G YLH + ++HRDLKL N+ ++E L +KI DFG A V + E
Sbjct: 149 TEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDL-EVKIGDFGLATKVEYDGER 207
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFE 227
+ G+ +APEV + K VD+WS+G +M+ KP F K +
Sbjct: 208 KKTLCGTPNYIAPEVLSK-KEHSFEVDVWSIGCIMYTLL--VGKPPFETSCLK---ETYL 261
Query: 228 AYTKN----PTTLN-ISIDLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
KN P +N ++ L K+L D R +I +++ND FF +
Sbjct: 262 RIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGY 309
>Hs7706401 [T] KOG0577 Serine/threonine protein kinase
Length = 1235
Score = 76.6 bits (187), Expect = 4e-14
Identities = 60/170 (35%), Positives = 88/170 (51%), Gaps = 13/170 (7%)
Query: 42 LALKKFR-SWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHT--ITFPYYSYTVL 98
+A+KK S N + +KE L+KL H I+ C R+HT + Y +
Sbjct: 54 VAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSAS 113
Query: 99 YLMKMSMLPTFE-ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGS 157
L+++ P E E A +G+AYLHSHN++HRD+K NI++ E +K+ DFGS
Sbjct: 114 DLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGL-VKLGDFGS 172
Query: 158 AVDVGPNKEACHGIRGSEQLMAPEVFQRL---KYEGTPVDMWSLGIMMFE 204
A + P + G+ MAPEV + +Y+G VD+WSLGI E
Sbjct: 173 ASIMAP----ANSFVGTPYWMAPEVILAMDEGQYDG-KVDVWSLGITCIE 217
>Hs4759208 [T] KOG0577 Serine/threonine protein kinase
Length = 1049
Score = 76.6 bits (187), Expect = 4e-14
Identities = 60/170 (35%), Positives = 88/170 (51%), Gaps = 13/170 (7%)
Query: 42 LALKKFR-SWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHT--ITFPYYSYTVL 98
+A+KK S N + +KE L+KL H I+ C R+HT + Y +
Sbjct: 54 VAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSAS 113
Query: 99 YLMKMSMLPTFE-ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGS 157
L+++ P E E A +G+AYLHSHN++HRD+K NI++ E +K+ DFGS
Sbjct: 114 DLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGL-VKLGDFGS 172
Query: 158 AVDVGPNKEACHGIRGSEQLMAPEVFQRL---KYEGTPVDMWSLGIMMFE 204
A + P + G+ MAPEV + +Y+G VD+WSLGI E
Sbjct: 173 ASIMAP----ANSFVGTPYWMAPEVILAMDEGQYDG-KVDVWSLGITCIE 217
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 76.6 bits (187), Expect = 4e-14
Identities = 70/289 (24%), Positives = 122/289 (41%), Gaps = 47/289 (16%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK 85
G C V K+A+KK + + ++E +LL+ +H+ I+ D
Sbjct: 72 GIVCSA--VDSETNEKVAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVAIRDVILPP 129
Query: 86 HTITFPYYSYTVLYLMKMSMLPTFE-------ERALWFC-QICEGIAYLHSHNIVHRDLK 137
+F Y V LM+ + T + + ++F QI G+ Y+HS N++HRDLK
Sbjct: 130 QRDSFEDV-YIVNELMEFDLYRTLKSDQELTKDHGMYFMYQILRGLKYIHSANVLHRDLK 188
Query: 138 LENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWS 197
N+++ + C++KI DFG A P + APE+ +D+WS
Sbjct: 189 PSNLLL-STQCDLKICDFGLA-RATPESNLMTEYVVTRWYRAPELLLGSSDYTAAIDVWS 246
Query: 198 LGIMMFEFFNNSNKPAFPWK-------------------------------IAKIDDVAF 226
+G + E N +P FP K I ++ +
Sbjct: 247 VGCIFMEIMN--REPLFPGKDQVNQLRLLLELIGTPSEEELGSLSEYAKRYIRQLPTLPR 304
Query: 227 EAYT-KNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVD 274
+++T K P ++IDL K+L+ D KQR+S+++ + + H+ D
Sbjct: 305 QSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEALAHPYLSSFHDITD 353
>7291707 [T] KOG1152 Signal transduction serine/threonine kinase with
PAS/PAC sensor domain
Length = 1005
Score = 76.6 bits (187), Expect = 4e-14
Identities = 64/223 (28%), Positives = 111/223 (49%), Gaps = 21/223 (9%)
Query: 57 KEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLMKMSMLPTFEER-- 112
KEV + E LL+ LNHK I+ LD N + + + + + P +E+
Sbjct: 624 KEVPI-EIHLLQTLNHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLG 682
Query: 113 ALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIR 172
+ F Q+ + + YLH I+HRD+K ENI++D++ IK+IDFGSA + K
Sbjct: 683 SYIFRQVADAVNYLHEQKILHRDIKDENIIIDQNF-TIKLIDFGSATFMEEGK-FFSTFY 740
Query: 173 GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF--EFFNNSNKPAFPWKIAKID-DVAFEAY 229
G+ + +PEV +Y G +++W+LG+ ++ FF N P+ ID + +A
Sbjct: 741 GTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFFEN------PF----IDVEETLKAE 790
Query: 230 TKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENHN 271
+ P ++ + L +L+ D K R ++ +I D + + N
Sbjct: 791 IQIPKAVSEQLSRLLSSMLNKDPKYRCTMHQLITDPWLTQEVN 833
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 76.6 bits (187), Expect = 4e-14
Identities = 55/175 (31%), Positives = 90/175 (51%), Gaps = 11/175 (6%)
Query: 99 YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA 158
Y++K L + R +F QI G+ Y H H IVHRDLK EN+++D ++ ++KI DFG +
Sbjct: 116 YIVKHGKLQEHQARR-FFQQIISGVDYCHRHMIVHRDLKPENLLLDHNM-HVKIADFGLS 173
Query: 159 VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS---NKPAFP 215
++ + E GS APEV Y G VD+WS G++++ + + P
Sbjct: 174 -NMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVP 232
Query: 216 WKIAKIDDVAFEAYTKNPTTLNIS-IDLCMKLLSVDVKQRLSIQDVINDSFFQEN 269
KI F P LN ++L ++L VD +R +I+++ +FQ++
Sbjct: 233 TLFRKIKSGIFPI----PEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKD 283
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 445
Score = 76.3 bits (186), Expect = 5e-14
Identities = 68/225 (30%), Positives = 108/225 (47%), Gaps = 30/225 (13%)
Query: 63 EYELLKKLNHKCIIEA-LDCNKRKHTITFPYY---SYTVLYLMKMSMLPTFEERALWFCQ 118
E +L+KL+H II+ ++ N F YL K+ +P + F Q
Sbjct: 206 EMTILRKLDHPNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMF-Q 264
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMV---DESLCNIKIIDFGSAVDVGPNKEACHGIRGSE 175
I +G+ YLH NI+HRDLKLENI++ +++ I + DFG A + K + G+
Sbjct: 265 ILQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFV-GTP 323
Query: 176 QLMAPEVFQRLKYE-----------GTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDV 224
+ APE+ QRLK G VD+WSLG++MF + N P+F + K V
Sbjct: 324 EYTAPEI-QRLKGRSQVEKENSSGYGKEVDLWSLGVIMF-LLLSGNSPSFADGV-KEKQV 380
Query: 225 AFEAYTKNPTTLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFF 266
F ++P ++S DL LL + R +++ ++ +F
Sbjct: 381 DF----RDPVWKSVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWF 421
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 76.3 bits (186), Expect = 5e-14
Identities = 54/176 (30%), Positives = 89/176 (49%), Gaps = 9/176 (5%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK--HTITFP 91
V K+ G + A K + L + +E + +KL H I+ D + + H + F
Sbjct: 30 VHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFD 89
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDESL-- 147
+ L+ + + E C QI E IAY HS+ IVHRDLK EN+++
Sbjct: 90 LVTGGELF-EDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG 148
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+K+ DFG A++V + EA HG G+ ++PEV ++ Y PVD+W+ G++++
Sbjct: 149 AAVKLADFGLAIEVN-DSEAWHGFAGTPGYLSPEVLKKDPY-SKPVDIWACGVILY 202
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 76.3 bits (186), Expect = 5e-14
Identities = 48/165 (29%), Positives = 82/165 (49%), Gaps = 9/165 (5%)
Query: 109 FEERALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEA 167
FE + F QI + +++ H + +VHRD+K ENI+VD +KI DFGS + +G E
Sbjct: 113 FEPQTASFAKQILQALSHCHRYGVVHRDIKPENILVDLRNDTVKICDFGSGIWLGEG-ET 171
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFE 227
G+ G+ +APEV Y G VD+WS G++++ + P + +I +
Sbjct: 172 TEGVVGTPYYVAPEVLMGYSY-GEKVDLWSAGVVLYTMLAGT-PPFYGETAEEIFEAVLR 229
Query: 228 AYTKNPTTL-----NISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+ PT + +++ D KL+ D +R S + + + Q
Sbjct: 230 GNLRFPTKIFRGVSSMAKDFLRKLICKDASRRFSAEQALRHPWIQ 274
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 76.3 bits (186), Expect = 5e-14
Identities = 59/192 (30%), Positives = 99/192 (50%), Gaps = 26/192 (13%)
Query: 36 KSDGSKLALK----KFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFP 91
K G K+A+K K+ SW+ + + ++E + LKKL+H I++ + + T+ F
Sbjct: 24 KDTGEKVAIKRMKRKYYSWE-----EAMNLREVKSLKKLSHPNIVKLKEVIRENDTLYFV 78
Query: 92 Y-YSYTVLYLM---KMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESL 147
+ Y LY M + + LP E +++ F Q+ G+A++H H HRDLK EN+ L
Sbjct: 79 FEYMKENLYQMIKDRDTHLPEPELKSILF-QVLTGLAFMHRHGFFHRDLKPENL-----L 132
Query: 148 CN----IKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
C+ IKI DFG A ++ + + APEV G+ +D+W++G +M
Sbjct: 133 CSGPDLIKIADFGLAREIRSRPPFTDYV-STRWYRAPEVLLHSTNYGSTIDLWAMGCIMA 191
Query: 204 EFFNNSNKPAFP 215
E + + +P FP
Sbjct: 192 ELY--TFRPLFP 201
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 75.9 bits (185), Expect = 7e-14
Identities = 61/225 (27%), Positives = 108/225 (47%), Gaps = 24/225 (10%)
Query: 62 KEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLMKMSMLPTFEERAL----- 114
KE +LL++L HK +I+ +D N+ K + + Y V + +M L + E+
Sbjct: 97 KEIQLLRRLRHKNVIQLVDVLYNEEKQKM-YMVMEYCVCGMQEM--LDSVPEKRFPVCQA 153
Query: 115 --WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGP--NKEACHG 170
+FCQ+ +G+ YLHS IVH+D+K N+++ +KI D G A + P + C
Sbjct: 154 HGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTG-GTLKISDLGVAEALHPFAADDTCRT 212
Query: 171 IRGSEQLMAPEVFQRL-KYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKI----DDVA 225
+GS PE+ L + G VD+WS G+ ++ N +P++ I +++
Sbjct: 213 SQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLY----NITTGLYPFEGDNIYKLFENIG 268
Query: 226 FEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+Y DL +L + +R SI+ + S+F++ H
Sbjct: 269 KGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKH 313
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 75.9 bits (185), Expect = 7e-14
Identities = 64/261 (24%), Positives = 119/261 (45%), Gaps = 34/261 (13%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF-------- 90
G ++A+K L+ + +E ++K LNH I++ + + + T+
Sbjct: 79 GREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGG 138
Query: 91 PYYSYTVLY-LMK-----------------MSMLPTFEERALWFCQICEGIAYLHSHNIV 132
+ Y V + MK + + +F+ +L F I + Y H IV
Sbjct: 139 EVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIV 198
Query: 133 HRDLKLENIMVDESLCNIKIIDFGSAVD--VGPNKEACHGIRGSEQLMAPEVFQRLKYEG 190
HRDLK EN+++D + NIKI DFG + + VG + GS APE+FQ KY+G
Sbjct: 199 HRDLKAENLLLDADM-NIKIADFGFSNEFTVGGKLDT---FCGSPPYAAPELFQGKKYDG 254
Query: 191 TPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSV 249
VD+WSLG++++ + S P + ++ + + P ++ + L + L +
Sbjct: 255 PEVDVWSLGVILYTLVSGS-LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVL 313
Query: 250 DVKQRLSIQDVINDSFFQENH 270
+ +R +++ ++ D + H
Sbjct: 314 NPIKRGTLEQIMKDRWINAGH 334
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 75.9 bits (185), Expect = 7e-14
Identities = 54/163 (33%), Positives = 83/163 (50%), Gaps = 17/163 (10%)
Query: 116 FCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG--------SAVDVGPNKEA 167
F Q+ + Y H +IVHRDLK EN+++D+ NIK+ DFG S + +K
Sbjct: 117 FRQLSSAVKYCHDLDIVHRDLKCENLLLDKDF-NIKLSDFGFSKRCLRDSNGRIILSKTF 175
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFE 227
C GS APEV Q + Y+ D+WSLG++++ S P I K+ + E
Sbjct: 176 C----GSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGS-MPYDDSDIRKMLRIQKE 230
Query: 228 AYTKNPTTLNISI---DLCMKLLSVDVKQRLSIQDVINDSFFQ 267
P + N++ DL ++L DV QRL I ++++ S+ Q
Sbjct: 231 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ 273
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 75.9 bits (185), Expect = 7e-14
Identities = 67/268 (25%), Positives = 127/268 (47%), Gaps = 22/268 (8%)
Query: 38 DGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK---HTITFPYYS 94
+G +A+K+ ++ ++E +LLK LNHK I++ L K K H I +
Sbjct: 42 NGDFVAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIVKYLGSLKTKTHLHIILEYVEN 101
Query: 95 YTVLYLMKMSMLPTFEER--ALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESLCNIK 151
++ ++K + F E ++ Q+ EG+ YLH ++HRD+K NI+ E L +K
Sbjct: 102 GSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL--VK 159
Query: 152 IIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE------- 204
+ DFG A + H + G+ MAPEV + L D+WS+G + E
Sbjct: 160 LADFGVATKLNEADFNTHSVVGTPYWMAPEVIE-LSGVCAASDIWSVGCTIIELLTCVPP 218
Query: 205 FFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDS 264
+++ PA ++I + DD + +P + + LC K D +QR + +++
Sbjct: 219 YYDLQPMPAL-YRIVQ-DDTPPIPDSLSPDITDF-LRLCFK---KDSRQRPDAKTLLSHP 272
Query: 265 FFQENHNSVDGVSAHARTKRILERSQTT 292
+ + + ++ H+ T R ++ + ++
Sbjct: 273 WIRNSRRALRSSLRHSGTIRYMKETDSS 300
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 75.9 bits (185), Expect = 7e-14
Identities = 59/217 (27%), Positives = 105/217 (48%), Gaps = 20/217 (9%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLM-KMSMLPTFEE--RALWFCQ 118
+E ++++L+H I++ + K I F L K+S E +F Q
Sbjct: 69 REISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQ 128
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAV---DVGPNKEACHGIRGSE 175
+ + Y H+ + HRDLK EN+++DE+ N+K+ DFG + + P+ H + G+
Sbjct: 129 LISAVGYCHARGVYHRDLKPENLLIDEN-GNLKVSDFGLSALTDQIRPDG-LLHTLCGTP 186
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAY 229
+APE+ + YEG VD+WS GI++F FN+ N KI K + F +
Sbjct: 187 AYVAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYK-GEYRFPRW 245
Query: 230 TKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFF 266
+S +LL ++ + R++I +++ D +F
Sbjct: 246 MSPDLKRFVS-----RLLDINPETRITIDEILKDPWF 277
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 75.5 bits (184), Expect = 8e-14
Identities = 53/168 (31%), Positives = 84/168 (49%), Gaps = 7/168 (4%)
Query: 40 SKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI----TFPYYSY 95
+++A+K L + E +E +++K L+H II+ + K + +
Sbjct: 44 TEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGE 103
Query: 96 TVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDF 155
YL L E R F QI + Y H IVHRDLK EN+++D ++ NIKI DF
Sbjct: 104 IFDYLANHGRLNESEARRK-FWQILSAVDYCHGRKIVHRDLKAENLLLDNNM-NIKIADF 161
Query: 156 GSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
G + + E GS APEVF+ +YEG +D+WS+G++++
Sbjct: 162 GFG-NFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLY 208
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 75.5 bits (184), Expect = 8e-14
Identities = 67/251 (26%), Positives = 113/251 (44%), Gaps = 33/251 (13%)
Query: 36 KSDGS--KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFP 91
K+D S K+ +K + + + E LLKK+ H II +D + I
Sbjct: 24 KNDASHQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHPLIIGYIDSFIMDNQLGIVMQ 83
Query: 92 YYSYTVLY--------LMKMSMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENI 141
Y L + +M F E+ + +F QI + ++H NIVHRDLK +NI
Sbjct: 84 YAEGGTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNI 143
Query: 142 MVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIM 201
+++ +K+ DFG + ++G K A + G+ ++PE+ + Y DMWSLG +
Sbjct: 144 LMNRRKTVLKLSDFGISKELG-TKSAASTVIGTPNYLSPEICESRPY-NQKSDMWSLGCV 201
Query: 202 MFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCM---KLLSVDVK 252
++E F+ N PA KI + +NP ++S D+ M LL
Sbjct: 202 LYELLQLERAFDGENLPAIVMKITR--------SKQNPLGDHVSNDVKMLVENLLKTHTD 253
Query: 253 QRLSIQDVIND 263
+R + +++D
Sbjct: 254 KRPDVSQLLSD 264
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 75.5 bits (184), Expect = 8e-14
Identities = 64/256 (25%), Positives = 119/256 (46%), Gaps = 16/256 (6%)
Query: 25 QGTTCEVEIVSKSD-GSKLALKKF-RSWDLHNHHKEVCVKEYELLKKLNHKCIIEALD-- 80
+GT +V+ +D G +A+K +S L N + +E ++K + H I+ +
Sbjct: 19 EGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYEVL 78
Query: 81 CNKRKHTITFPYYSYTVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKL 138
+ K I + + L+ ++ L E R +F Q+ + +A+ H + HRDLK
Sbjct: 79 ASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRK-YFQQLVDAVAHCHCKGVYHRDLKP 137
Query: 139 ENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSL 198
EN+++D + N+K+ DFG + E G+ +APEV Y+G+ D+WS
Sbjct: 138 ENLLLDTN-GNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSAADIWSC 196
Query: 199 GIMMFEF---FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQR 254
G+++F + ++ P KI+ F P + + L ++L + K R
Sbjct: 197 GVILFVILAGYLPFSETDLPGLYRKINAAEFSC----PPWFSAEVKFLIHRILDPNPKTR 252
Query: 255 LSIQDVINDSFFQENH 270
+ IQ + D +F+ N+
Sbjct: 253 IQIQGIKKDPWFRLNY 268
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 75.1 bits (183), Expect = 1e-13
Identities = 59/200 (29%), Positives = 98/200 (48%), Gaps = 35/200 (17%)
Query: 95 YTVLYLMKMSMLPTFEERALWFCQIC---------EGIAYLHSHNIVHRDLKLENIMVDE 145
Y VL L + L + + F +IC + I Y+H ++HRDLK ENI++D+
Sbjct: 174 YFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGRGVIHRDLKPENILLDD 233
Query: 146 SLCNIKIIDFGSAVDV----GPNKEACH----------GIRGSEQLMAPEVFQRLKYEGT 191
++ KI DFGSA + G ++E H G+ + ++PEV K GT
Sbjct: 234 NM-RTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVLSD-KIAGT 291
Query: 192 PVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFE-----AYTKNPTTLNISIDLCMKL 246
D+W+ G ++F+ + KP F +A + + F+ +Y P +++ DL KL
Sbjct: 292 ASDIWAFGCILFQML--AGKPPF---VAGNEYLTFQSILHLSYEIPPDISDVASDLIKKL 346
Query: 247 LSVDVKQRLSIQDVINDSFF 266
L +D K RL++ ++ FF
Sbjct: 347 LVLDPKDRLTVDEIHQHPFF 366
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 20/215 (9%)
Query: 62 KEYELLKKLNHKCIIEALDCNK-RKHTITFPYYSYTVLYLM--KMSMLPTFEERALWFCQ 118
+E +L++L+H II + K+T+ Y T L+ M K + L R + F Q
Sbjct: 70 REVTILRQLHHPNIITLYQVFRVPKYTVLALEYMDTDLHSMVVKHNRLDECTTRKI-FRQ 128
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA---VDVGPNKEACHGIRGSE 175
I I Y H H + HRDLKLENI++++ L +K+ DFG + +D +C G+
Sbjct: 129 IVHAIDYCHLHRVAHRDLKLENILLNKDLV-VKLTDFGLSNFMLDGSFLSTSC----GTP 183
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEA----YTK 231
APEV Q Y+G VD+W GI+++ FP++ I +V YT
Sbjct: 184 HYAAPEVIQGRYYDGCDVDVWGCGILLYLMLVGE----FPFEDVTISNVLSRVCKGIYTI 239
Query: 232 NPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFF 266
+ + DL ++L V R+ + +++ +F
Sbjct: 240 PSFVSSSASDLIRQMLMVLPTSRIKVAEIMQHPWF 274
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 75.1 bits (183), Expect = 1e-13
Identities = 53/173 (30%), Positives = 91/173 (51%), Gaps = 7/173 (4%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYY 93
K+ G +A+K F + +K + ++E + LK+ +H+ ++ ++ K+K + F +
Sbjct: 24 KNTGQIVAIKIFYERPEQSVNK-IAMREIKFLKQFHHENLVNLIEVFRQKKKIHLVFEFI 82
Query: 94 SYTVLYLMKMSMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIK 151
+TVL ++ E + L + QI I YLHS+NI+HRD+K ENI+V +S K
Sbjct: 83 DHTVLDELQ-HYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGIT-K 140
Query: 152 IIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
+ DFG A + + + APE+ + G PVD+W+LG M+ E
Sbjct: 141 LCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIE 193
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 75.1 bits (183), Expect = 1e-13
Identities = 73/253 (28%), Positives = 114/253 (44%), Gaps = 20/253 (7%)
Query: 29 CEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKH 86
C + K +K K+ S +E +E +L+++ H II D NK
Sbjct: 30 CRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIITLHDIFENKTDV 89
Query: 87 TITFPYYSYTVLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLENIM-VD 144
+ S L+ E+ A F QI +G+ YLHS I H DLK ENIM +D
Sbjct: 90 VLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLD 149
Query: 145 ESLCN--IKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYE--GTPVDMWSLGI 200
+++ N IK+IDFG A + E I G+ + +APE+ + YE G DMWS+G+
Sbjct: 150 KNVPNPRIKLIDFGIAHKIEAGNE-FKNIFGTPEFVAPEI---VNYEPLGLEADMWSIGV 205
Query: 201 MMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQR 254
+ + F K I+ ++ E Y N T ++ D +LL D K+R
Sbjct: 206 ITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSN--TSELAKDFIRRLLVKDPKRR 263
Query: 255 LSIQDVINDSFFQ 267
++I + S+ +
Sbjct: 264 MTIAQSLEHSWIK 276
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 75.1 bits (183), Expect = 1e-13
Identities = 73/291 (25%), Positives = 117/291 (40%), Gaps = 46/291 (15%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYL 100
K+A+KK H +E LLK L H+ +I LD +I Y V L
Sbjct: 49 KVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTL 108
Query: 101 MKMSMLPTFEERAL-------WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKII 153
M + + +AL Q+ G+ Y+HS I+HRDLK N+ V+E C ++I+
Sbjct: 109 MGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRIL 167
Query: 154 DFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPA 213
DFG A E G + APE+ + VD+WS+G +M E K
Sbjct: 168 DFGLARQA---DEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELL--QGKAL 222
Query: 214 FPWK--------------------IAKIDDVAFEAYTKNPTTL-------------NISI 240
FP +AKI Y ++ + ++I
Sbjct: 223 FPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAI 282
Query: 241 DLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHARTKRILERSQT 291
DL ++L +D QR+S + + ++F + H+ D A + + + +T
Sbjct: 283 DLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKERT 333
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 75.1 bits (183), Expect = 1e-13
Identities = 58/170 (34%), Positives = 86/170 (50%), Gaps = 13/170 (7%)
Query: 42 LALKKFRSWDLHNHHK-EVCVKEYELLKKLNHKCIIEALDCNKRKHT--ITFPYYSYTVL 98
+A+KK H K + +KE + L++L H IE C ++HT + Y +
Sbjct: 50 VAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSAS 109
Query: 99 YLMKMSMLPTFE-ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGS 157
L+++ P E E A G+AYLHSH ++HRD+K NI++ E +K+ DFGS
Sbjct: 110 DLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEP-GQVKLADFGS 168
Query: 158 AVDVGPNKEACHGIRGSEQLMAPEVFQRL---KYEGTPVDMWSLGIMMFE 204
A P + G+ MAPEV + +Y+G VD+WSLGI E
Sbjct: 169 ASMASP----ANSFVGTPYWMAPEVILAMDEGQYDG-KVDIWSLGITCIE 213
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 75.1 bits (183), Expect = 1e-13
Identities = 58/173 (33%), Positives = 89/173 (50%), Gaps = 9/173 (5%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKH--TITFPYY 93
KS G LA K + + +E E ++ +L+H +I+ D + KH T+ Y
Sbjct: 511 KSTGLPLAAKIIKVKSAKD--REDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYV 568
Query: 94 SYTVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESLCNI 150
L+ + T + L+ QICEG+ YLH H I+H DLK ENI+ V+++ I
Sbjct: 569 DGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQI 628
Query: 151 KIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
KIIDFG A P +E G+ + +APEV ++ P DMWS+G++ +
Sbjct: 629 KIIDFGLARRYKP-REKLKVNFGTPEFLAPEVV-NYEFVSFPTDMWSVGVITY 679
>At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 277
Score = 75.1 bits (183), Expect = 1e-13
Identities = 52/162 (32%), Positives = 85/162 (52%), Gaps = 11/162 (6%)
Query: 111 ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHG 170
E A + QI +A+ H ++VHRD+K +N++VD +K+ DFGSAV +G E G
Sbjct: 113 ESASYAKQILSALAHCHRCDVVHRDVKPDNVLVDLVSGGVKLCDFGSAVWLG--GETAEG 170
Query: 171 IRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAK-IDDVAFEAY 229
+ G+ +APEV KY+ VD+WS G++++ + +P F + A+ I +
Sbjct: 171 VVGTPYYVAPEVVMGRKYD-EKVDIWSAGVVIYTML--AGEPPFNGETAEDIFESILRGN 227
Query: 230 TKNPTTLNISI-----DLCMKLLSVDVKQRLSIQDVINDSFF 266
+ P S+ DL K++ DV +R S +D + S F
Sbjct: 228 LRFPPKKFGSVSSEAKDLLRKMICRDVSRRFSAEDALRKSSF 269
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/272 (23%), Positives = 118/272 (43%), Gaps = 43/272 (15%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFP-- 91
V++ ++A+KK + + ++E +LL+ L H+ ++ D H +F
Sbjct: 50 VNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENVVALKDVMMANHKRSFKDV 109
Query: 92 YYSYTVL-----YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDES 146
Y Y ++ ++K S + + + + Q+ G+ Y+HS NI+HRDLK N++V+ +
Sbjct: 110 YLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNAN 169
Query: 147 LCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
C++KI DFG A + + APE+ GT +D+WS+G + E
Sbjct: 170 -CDLKICDFGLARTSNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELL 228
Query: 207 NNSNKPAFPW--------------------KIAKIDDVAFEAYTKN-------------P 233
KP FP + ID+ + Y ++ P
Sbjct: 229 --GRKPVFPGTECLNQIKLIINILGSQREEDLEFIDNPKAKRYIESLPYSPGISFSRLYP 286
Query: 234 TTLNISIDLCMKLLSVDVKQRLSIQDVINDSF 265
++IDL K+L +D +R+S+ + + +
Sbjct: 287 GANVLAIDLLQKMLVLDPSKRISVTEALQHPY 318
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 74.7 bits (182), Expect = 1e-13
Identities = 69/210 (32%), Positives = 100/210 (46%), Gaps = 23/210 (10%)
Query: 67 LKKLNHKCIIEALDC--NKRKHTITFPYYSYT----VLYLMKMSMLPTFEERALWFCQIC 120
L K H+ I+ LD + + I P + T + L++ T E L F Q+
Sbjct: 1156 LNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVV 1215
Query: 121 EGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA--VDVGPNKEACHGIRGSEQLM 178
GI +LH IVHRD+K EN++VD S +KIIDFGSA V GP G+
Sbjct: 1216 AGIKHLHDQGIVHRDIKDENVIVD-SKGFVKIIDFGSAAYVKSGP----FDVFVGTIDYA 1270
Query: 179 APEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNI 238
APEV YEG P D+W++GI+++ N ID++ E K +
Sbjct: 1271 APEVLGGNPYEGQPQDIWAIGILLYTVVFKEN------PFYNIDEI-LEGDLKFNNAEEV 1323
Query: 239 S---IDLCMKLLSVDVKQRLSIQDVINDSF 265
S I+L +L+ V +R +I D+ ND +
Sbjct: 1324 SEDCIELIKSILNRCVPKRPTIDDINNDKW 1353
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 74.7 bits (182), Expect = 1e-13
Identities = 68/230 (29%), Positives = 111/230 (47%), Gaps = 28/230 (12%)
Query: 56 HKEV-CVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTF----- 109
+KE+ V+E L L H I EA D IT +Y ++ ML
Sbjct: 183 NKEIRTVREAALSTLLRHPYICEARDVY-----ITNSHYYMVFEFVDGGQMLDYIISHGK 237
Query: 110 --EERALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKE 166
E++A F QI ++YLH +++VHRDLK+ENI++ ++ +IKIIDFG + ++ +
Sbjct: 238 LKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKT-GDIKIIDFGLS-NLYRRQS 295
Query: 167 ACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAK 220
GS APE+ Y G VD+WS GI+++ F++ N A KI K
Sbjct: 296 RLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKK 355
Query: 221 IDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
V + +Y + L ++L D +R ++++V+N + N+
Sbjct: 356 -GTVEYPSYLSSDCK-----GLLSRMLVTDPLKRATLEEVLNHPWMIRNY 399
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 74.7 bits (182), Expect = 1e-13
Identities = 71/253 (28%), Positives = 119/253 (46%), Gaps = 30/253 (11%)
Query: 33 IVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKL-NHKCIIEALDCNKRKHTITFP 91
+V+ G K ALK + +N + V V+ LL +L H I +DC R T+
Sbjct: 70 VVNILTGEKAALKMI-PFTPNNTSQTVRVQREALLGRLLRHPNICRVIDCI-RTPACTYI 127
Query: 92 YYSYT-----VLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDE 145
+ Y + Y++ L E+ A F Q+ + YLH + IVHRDLK+EN+++ +
Sbjct: 128 LFEYVPGGQLLEYILARGKLD--EDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLTQ 185
Query: 146 SLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF 205
+K+IDFG + + + GS APE+ Y G VD+WSLG++++
Sbjct: 186 DSRQVKLIDFGLS-NFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWSLGVVIYVM 244
Query: 206 ------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLC---MKLLSVDVKQRLS 256
F++ + P KI K + F +Y IS D C +L+V+ ++R S
Sbjct: 245 VCGRVPFDDVSVPMLHSKI-KSGKLEFPSY--------ISEDCCSLIAAMLNVNPRKRCS 295
Query: 257 IQDVINDSFFQEN 269
++ + ++N
Sbjct: 296 LEQAAKFPWLKKN 308
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 74.7 bits (182), Expect = 1e-13
Identities = 52/177 (29%), Positives = 85/177 (47%), Gaps = 14/177 (7%)
Query: 38 DGSKLALKKFRSWDLHNHH-KEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY---- 92
D +ALKK + +++ + ++ CVKE LLK+LNH II+ LD + +
Sbjct: 67 DRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELAD 126
Query: 93 ---YSYTVLYLMKMSMLPTFEERALW--FCQICEGIAYLHSHNIVHRDLKLENIMVDESL 147
S + Y K L ER +W F Q+C + ++HS ++HRD+K N+ + +
Sbjct: 127 AGDLSQMIKYFKKQKRL--IPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATG 184
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
+K+ D G A H + G+ M+PE Y D+WSLG +++E
Sbjct: 185 V-VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY-NFKSDIWSLGCLLYE 239
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 74.7 bits (182), Expect = 1e-13
Identities = 60/198 (30%), Positives = 94/198 (47%), Gaps = 17/198 (8%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC---N 82
GT C E G+++A+KKF H +E LL+ + H+ II+ LD N
Sbjct: 47 GTVCAAECTRS--GTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPN 104
Query: 83 KRKHTITFPYYSYTVL-----YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLK 137
+ + I Y+ ++ ++K+ L + L + QI G+ Y+HS +I+HRDLK
Sbjct: 105 ENVNDIEDVYFVSMLMGADLSNILKIQRLNDDHIQFLVY-QILRGLKYIHSADIIHRDLK 163
Query: 138 LENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWS 197
NI V+E C +KI+DFG A G + APE+ + VD+WS
Sbjct: 164 PSNIAVNED-CELKILDFGLARQTDSEMT---GYVATRWYRAPEIMLNWMHYTQTVDVWS 219
Query: 198 LGIMMFEFFNNSNKPAFP 215
+G ++ E + K FP
Sbjct: 220 VGCILAELI--TGKTLFP 235
>At4g26890 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 444
Score = 74.7 bits (182), Expect = 1e-13
Identities = 78/270 (28%), Positives = 124/270 (45%), Gaps = 37/270 (13%)
Query: 21 PRLIQGTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEAL- 79
P + +G+T V I S G A+K S DL + + KE +L L+ +++ +
Sbjct: 9 PIIGRGSTATVSIAISSSGELFAVK---SADLSS--SSLLQKEQSILSTLSSPHMVKYIG 63
Query: 80 -----DCNKRKHTITFPYYSYTVLY-LMKMS--MLPTFEERALWFCQICEGIAYLHSHNI 131
+ N + I Y S L+ L+K S LP E R+ + QI G+ YLH I
Sbjct: 64 TGLTRESNGLVYNILMEYVSGGNLHDLIKNSGGKLPEPEIRS-YTRQILNGLVYLHERGI 122
Query: 132 VHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGT 191
VH DLK N++V+E+ +KI D G A V ++ G+ MAPEV R + +
Sbjct: 123 VHCDLKSHNVLVEENGV-LKIADMGCAKSVDKSE-----FSGTPAFMAPEV-ARGEEQRF 175
Query: 192 PVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISI---------DL 242
P D+W+LG M E S+ PW +++DV Y + + +I D
Sbjct: 176 PADVWALGCTMIEMMTGSS----PW--PELNDVVAAMYKIGFSGESPAIPAWISDKAKDF 229
Query: 243 CMKLLSVDVKQRLSIQDVINDSFFQENHNS 272
L D KQR ++++++ F ++ S
Sbjct: 230 LKNCLKEDQKQRWTVEELLKHPFLDDDEES 259
>CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 392
Score = 74.3 bits (181), Expect = 2e-13
Identities = 44/147 (29%), Positives = 77/147 (51%), Gaps = 4/147 (2%)
Query: 56 HKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF--PYYSYTVLYLMKMSMLPTFEERA 113
HK++ E+++L +++ ++ + K + F P+ + M + E
Sbjct: 71 HKDMVEHEWKILTTIHNPFFMKMSYSFQTKRHLVFVMPFAGGGDMLTMMENECLIEESAH 130
Query: 114 LWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRG 173
+ C++ EGI YLH +IVHRD+KLEN+++ ++ I D+G + ++A G+ G
Sbjct: 131 FYLCELVEGIGYLHEKHIVHRDVKLENLLIGND-GHLMITDYGLSATGCDAEDAIQGVIG 189
Query: 174 SEQLMAPEVFQRLKYEGTPVDMWSLGI 200
+ MAPEV KY GT D W++GI
Sbjct: 190 TRHTMAPEVHLEKKY-GTSCDWWAVGI 215
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 74.3 bits (181), Expect = 2e-13
Identities = 72/282 (25%), Positives = 131/282 (45%), Gaps = 23/282 (8%)
Query: 22 RLIQGTTCEVEIV-SKSDGSKLALKKF-RSWDLHNHHKEVCVKEYELLKKL-NHKCIIEA 78
RL G+ +V + S S G +A+K + + + + ++E E +++L NH +++
Sbjct: 26 RLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLHNHPNVLKI 85
Query: 79 LD--CNKRKHTITFPYYSYTVLYLMKMSMLPTFEERAL--WFCQICEGIAYLHSHNIVHR 134
+ K K + Y + L+ K+ E A +F Q+ +++ H I HR
Sbjct: 86 HEVMATKSKIYLVVEYAAGGELFT-KLIRFGRLNESAARRYFQQLASALSFCHRDGIAHR 144
Query: 135 DLKLENIMVDESLCNIKIIDFGSAV--DVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTP 192
D+K +N+++D+ N+K+ DFG + + N H G+ APEV + Y+G
Sbjct: 145 DVKPQNLLLDKQ-GNLKVSDFGLSALPEHRSNNGLLHTACGTPAYTAPEVIAQRGYDGAK 203
Query: 193 VDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKL 246
D WS G+ +F F+++N A KI K D F ++ P + KL
Sbjct: 204 ADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHK-RDYRFPSWISKPAR-----SIIYKL 257
Query: 247 LSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHARTKRILER 288
L + + R+SI+ V+ +FQ++ + S+ R LE+
Sbjct: 258 LDPNPETRMSIEAVMGTVWFQKSLEISEFQSSVFELDRFLEK 299
>At1g07150 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 499
Score = 74.3 bits (181), Expect = 2e-13
Identities = 55/159 (34%), Positives = 82/159 (50%), Gaps = 12/159 (7%)
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLM 178
+ + ++HS VH D+K NI+V +S +K+ DFGSA + A RGS M
Sbjct: 134 LVSALRHVHSQGFVHCDVKARNILVSQS-SMVKLADFGSAFRI-HTPRALITPRGSPLWM 191
Query: 179 APEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKN----PT 234
APEV +R +Y+G D+WSLG + E F + KPA W+ ID ++ +++ P+
Sbjct: 192 APEVIRR-EYQGPESDVWSLGCTIIEMF--TGKPA--WEDHGIDSLSRISFSDELPVFPS 246
Query: 235 TLN-ISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNS 272
L+ I D K L D QR S ++ F + HNS
Sbjct: 247 KLSEIGRDFLEKCLKRDPNQRWSCDQLLQHPFLSQCHNS 285
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 74.3 bits (181), Expect = 2e-13
Identities = 51/170 (30%), Positives = 84/170 (49%), Gaps = 11/170 (6%)
Query: 40 SKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCII---EALDCNKRKHTITFPYYSYT 96
+K+A+K L+ + +E +LK L H I E ++ + +T +
Sbjct: 65 TKVAIKIIDKTCLNEEYLNKTFREIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGE 124
Query: 97 VLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG 156
+ + + E A F Q+ + Y H +VHRDLK EN+++D+ + NIK+ DFG
Sbjct: 125 IFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDM-NIKLADFG 183
Query: 157 SA---VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
+ + K C GS APEVFQ L+Y+G D+WSLG++++
Sbjct: 184 FSNHYEEGATLKTWC----GSPPYAAPEVFQGLEYDGPKSDIWSLGVVLY 229
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/216 (25%), Positives = 99/216 (44%), Gaps = 10/216 (4%)
Query: 62 KEYELLKKLNHKCIIEAL----DCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFC 117
+E E+ +L H +++ D N + + Y+ ++ T E A
Sbjct: 61 QEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILK 120
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
Q+ G+ YLHSHNI+HRD+ L N+++ + ++KI DFG A + E + G+
Sbjct: 121 QVVAGLLYLHSHNIMHRDISLSNLLLSREM-HVKIADFGLATQLKRPDERHMTMCGTPNY 179
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAK--IDDVAFEAYTKNPTT 235
++PEV R + G P D+WS+G M++ +P F + ++ V Y
Sbjct: 180 ISPEVVSRTSH-GLPADVWSVGCMLYTLL--VGRPPFETDAVQSTLNKVVMSEYIMPAHL 236
Query: 236 LNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHN 271
+ DL KLL +R++++ V+ F + N
Sbjct: 237 SYEAQDLINKLLKKLPHERITLEAVLCHPFMLKCSN 272
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 73.9 bits (180), Expect = 2e-13
Identities = 65/230 (28%), Positives = 111/230 (48%), Gaps = 25/230 (10%)
Query: 57 KEVCVKEYELLKKLN-HKCIIEALDCNKRKHTITFPYYSYTVL-------YLMKMSMLPT 108
+E +KE ++L+K++ H II+ D + T TF + + ++ YL + L
Sbjct: 68 REATLKEVDILRKVSGHPNIIQLKDTYE---TNTFFFLVFDLMKRGELFDYLTEKVTLSE 124
Query: 109 FEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEAC 168
E R + + E I LH NIVHRDLK ENI++D+++ NIK+ DFG + + P E
Sbjct: 125 KETRKIMRA-LLEVICTLHKLNIVHRDLKPENILLDDNM-NIKLTDFGFSCQLEPG-ERL 181
Query: 169 HGIRGSEQLMAPEVFQRLKYE-----GTPVDMWSLGIMMFEFFNNS-----NKPAFPWKI 218
+ G+ +APE+ + E G VDMWS G++M+ S K ++
Sbjct: 182 REVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRM 241
Query: 219 AKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+ F + + + + DL + L V + R + ++ + FFQ+
Sbjct: 242 IMSGNYQFGSPEWDDYSDTVK-DLVSRFLVVQPQNRYTAEEALAHPFFQQ 290
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 73.9 bits (180), Expect = 2e-13
Identities = 59/228 (25%), Positives = 105/228 (45%), Gaps = 24/228 (10%)
Query: 54 NHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTF---- 109
N KE+C+ K LNH+ +++ ++R+ I + + Y + + P
Sbjct: 51 NIKKEICIN-----KMLNHENVVKFYG-HRREGNIQYLFLEYCSGGELFDRIEPDIGMPE 104
Query: 110 EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPN--KEA 167
+ +F Q+ G+ YLH I HRD+K EN+++DE N+KI DFG A N +
Sbjct: 105 PDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDER-DNLKISDFGLATVFRYNNRERL 163
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFE 227
+ + G+ +APE+ +R ++ PVD+WS GI++ PW +
Sbjct: 164 LNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGE----LPWDQPSDSCQEYS 219
Query: 228 AYTKNPTTLN-------ISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+ + T LN + L K+L + R++I D+ D ++ +
Sbjct: 220 DWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNK 267
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 73.9 bits (180), Expect = 2e-13
Identities = 52/188 (27%), Positives = 94/188 (49%), Gaps = 15/188 (7%)
Query: 40 SKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLY 99
+++A+KK ++ H + + ++E ++L + H+ +I D R T+ Y V
Sbjct: 66 TRVAIKKISPFE-HQTYCQRTLREIQILLRFRHENVIGIRDI-LRASTLEAMRDVYIVQD 123
Query: 100 LMKMSMLPTFEERAL-------WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKI 152
LM+ + + + L + QI G+ Y+HS N++HRDLK N++++ + C++KI
Sbjct: 124 LMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLIN-TTCDLKI 182
Query: 153 IDFGSAVDVGPNKEACHGIR---GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS 209
DFG A P + + + APE+ K +D+WS+G ++ E S
Sbjct: 183 CDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML--S 240
Query: 210 NKPAFPWK 217
N+P FP K
Sbjct: 241 NRPIFPGK 248
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 73.9 bits (180), Expect = 2e-13
Identities = 70/281 (24%), Positives = 128/281 (44%), Gaps = 46/281 (16%)
Query: 23 LIQGTTCEVEI--VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYEL---LKKLNHKCIIE 77
L +G+ +V + ++++ K+A+K+ + KEY++ L K+ H+ +I+
Sbjct: 349 LCKGSFGQVHLCELTRNPSVKVAVKEVAVSGKSRKNLTAVQKEYKIHRRLSKIGHENVIQ 408
Query: 78 ALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERAL--------WFCQICEGIAYLHSH 129
+ K T +YS + Y + +E+ +F Q+ +G+ ++H
Sbjct: 409 MM-----KMIETPKFYSLVMEYADGGDLFDELKEQEKFSRKDAHSYFKQLIKGLKFIHEQ 463
Query: 130 NIVHRDLKLENIMV-----DESLCNIKIIDFGSAVDVGPN------KEACHGIRGSEQLM 178
IVHRD+KLEN+++ ++ +KI DFG A + E C GS+
Sbjct: 464 GIVHRDIKLENLLLVYSESEDDPGTLKITDFGLATKYRKDGEEIMLSEDC----GSKPYA 519
Query: 179 APEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIA-KIDDVAF----EAYTKNP 233
APEV Y G PVD+WS G+++ + WK+A K D A+ A +
Sbjct: 520 APEVCTGNDYRGPPVDIWSAGVVLMTMLVGEHS----WKVANKEKDAAYSNWINAKDEKA 575
Query: 234 TTLNI----SIDLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
N+ + L KLL + ++R ++ + D +F+ N+
Sbjct: 576 NLWNVISGPTTALLRKLLHANPEKRATMAKIEADPWFRYNY 616
Score = 64.3 bits (155), Expect = 2e-10
Identities = 38/122 (31%), Positives = 63/122 (51%), Gaps = 7/122 (5%)
Query: 110 EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPN--KEA 167
+E +F Q+ +G+ ++H + HRD+K EN+++ +S +KI DFG A N ++
Sbjct: 119 DEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGI-LKIADFGFATMHRFNGAEQM 177
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFE 227
+ GS +APEV + Y G VD+WS G+++ A PW+ A D+
Sbjct: 178 LNAYCGSPPYIAPEVLTGIDYRGPAVDIWSAGVVLIAMIAG----AVPWEQADHFDIFQS 233
Query: 228 AY 229
Y
Sbjct: 234 RY 235
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 73.9 bits (180), Expect = 2e-13
Identities = 68/278 (24%), Positives = 116/278 (41%), Gaps = 66/278 (23%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFP-- 91
++ ++A+KK + + ++E +LL+ + H+ +I D H +F
Sbjct: 50 INSETNERVAIKKIHNVFENRIDALRTLRELKLLRHVRHENVISLKDVMLPTHRYSFRDV 109
Query: 92 YYSYTVL-----YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDES 146
Y Y ++ ++K S + + + Q+ G+ YLHS NI+HRDLK N++V+ +
Sbjct: 110 YLVYELMDSDLNQIIKSSQSLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNAN 169
Query: 147 LCNIKIIDFGSAVDVGPNKEACHGIRGSEQLM----------APEVFQRLKYEGTPVDMW 196
C++KI DFG A R EQ M APE+ GT +D+W
Sbjct: 170 -CDLKICDFGLA-------------RTYEQFMTEYVVTRWYRAPELLLCCDNYGTSIDVW 215
Query: 197 SLGIMMFEFFNNSNKPAFP--------------------WKIAKIDDVAFEAYTKN---- 232
S+G + E KP FP W + ID+ + K+
Sbjct: 216 SVGCIFAEIL--GRKPIFPGTECLNQLKLIINVVGSQQDWDLQFIDNQKARRFIKSLPFS 273
Query: 233 ---------PTTLNISIDLCMKLLSVDVKQRLSIQDVI 261
P ++IDL ++L D +R+S+ D +
Sbjct: 274 KGTHFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDAL 311
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 73.9 bits (180), Expect = 2e-13
Identities = 66/260 (25%), Positives = 118/260 (45%), Gaps = 19/260 (7%)
Query: 26 GTTCEVEIVSK-SDGSKLALK-----KFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEAL 79
GT +V + G K+A+K K L H K +E +L+++ H I+
Sbjct: 83 GTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIK----REISILRRVRHPYIVHLF 138
Query: 80 DCNKRKHTITF--PYYSYTVLY-LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDL 136
+ K I F Y L+ + LP E +F Q+ +++ H + HRDL
Sbjct: 139 EVMATKSKIYFVMEYVGGGELFNTVAKGRLPE-ETARRYFQQLISSVSFCHGRGVYHRDL 197
Query: 137 KLENIMVDESLCNIKIIDFG-SAVDVGPNKEA-CHGIRGSEQLMAPEVFQRLKYEGTPVD 194
K EN+++D N+K+ DFG SAV ++ CH G+ +APEV R Y+ D
Sbjct: 198 KPENLLLDNK-GNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKAD 256
Query: 195 MWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNIS-IDLCMKLLSVDVKQ 253
+WS G+++F + P + I + ++ + P + + L +LL +
Sbjct: 257 VWSCGVILFVLM-AGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPDT 315
Query: 254 RLSIQDVINDSFFQENHNSV 273
R++I +++ + +F++ V
Sbjct: 316 RITIPEIMKNRWFKKGFKHV 335
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 73.9 bits (180), Expect = 2e-13
Identities = 45/157 (28%), Positives = 81/157 (50%), Gaps = 8/157 (5%)
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMV--DESLCNIKIIDFGSAVDVGPNKEACHGIRGSE 175
QI E + Y H +NI+HRD+K +++ E+ +K+ FG A+ +G + G G+
Sbjct: 124 QILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTP 183
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTT 235
MAPEV +R Y G PVD+W G+++F + P + K + + Y NP
Sbjct: 184 HFMAPEVVKREPY-GKPVDVWGCGVILFILLSGC-LPFYGTKERLFEGIIKGKYKMNPRQ 241
Query: 236 LN----ISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+ + DL ++L +D +R+++ + +N + +E
Sbjct: 242 WSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKE 278
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 73.6 bits (179), Expect = 3e-13
Identities = 68/228 (29%), Positives = 103/228 (44%), Gaps = 29/228 (12%)
Query: 57 KEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYS---YTVLYLMKMSMLPTFEERA 113
KE V E ++K +HK I+ +D TF Y S + Y+ S+
Sbjct: 425 KEFIVNEILVMKSHHHKNIVNFID--------TFFYKSELWMVMEYMRGGSLTEVVTNNT 476
Query: 114 LWFCQIC-------EGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKE 166
L QI EG+ +LH + IVHRD+K +NI++ +IK+ DFG + N
Sbjct: 477 LSEGQIAAICKETLEGLQHLHENGIVHRDIKSDNILLSLQ-GDIKLTDFGFCAQIDSNMT 535
Query: 167 ACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAK 220
+ G+ MAPEV R +Y G VD+WSLGIM E + N N + IA
Sbjct: 536 KRTTMVGTPYWMAPEVVTRKEY-GFKVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIAT 594
Query: 221 IDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
I ++ ++ D K L+V+ KQR S +++ F ++
Sbjct: 595 I---GTPKISRPELLSSVFHDFLSKSLTVNPKQRPSSGELLRHPFLKQ 639
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 73.6 bits (179), Expect = 3e-13
Identities = 56/171 (32%), Positives = 90/171 (51%), Gaps = 24/171 (14%)
Query: 110 EERALWF-CQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEAC 168
EERA ++ +I + YLHS ++V+RD+KLEN+M+D+ +IKI DFG + +
Sbjct: 249 EERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKD-GHIKITDFGLCKEGISDGATM 307
Query: 169 HGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE-------FFNNSNKPAFPWKIAKI 221
G+ + +APEV + Y G VD W LG++M+E F+N ++ F ++ +
Sbjct: 308 KTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLF--ELILM 364
Query: 222 DDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRL-----SIQDVINDSFF 266
+++ F P TL+ L LL D KQRL ++V+ FF
Sbjct: 365 EEIRF------PRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFF 409
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 73.6 bits (179), Expect = 3e-13
Identities = 60/231 (25%), Positives = 102/231 (43%), Gaps = 7/231 (3%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCII---EALDCNKRKHTITFPYYSYTV 97
K+A+K L + + +E ++KL+H II E ++ + H + +
Sbjct: 99 KVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGEL 158
Query: 98 LYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGS 157
+ + E L F QI + ++H + I+HRDLK EN+ + C +K+ DFG
Sbjct: 159 FGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTC-VKVGDFGF 217
Query: 158 AVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWK 217
+ V E + GS APE+F+ Y G VD+W+LG++++ F P
Sbjct: 218 ST-VSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLY-FMVTGTMPFRAET 275
Query: 218 IAKIDDVAFE-AYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+AK+ E Y+ P L +L +R I ++ND + Q
Sbjct: 276 VAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQ 326
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 73.6 bits (179), Expect = 3e-13
Identities = 74/252 (29%), Positives = 120/252 (47%), Gaps = 26/252 (10%)
Query: 25 QGTTCEV-EIVSKSDGSKLALKKF-RSWDLHNHHKEVCVKEYELLKKLNHKCII---EAL 79
+GT +V E SK K+A+K + + +E ++++ L+HK II E L
Sbjct: 18 EGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEML 77
Query: 80 DCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERA-LWFCQICEGIAYLHSHNIVHRDLKL 138
+ K + ++ ++ P E RA F Q+ E I Y H + HRDLK
Sbjct: 78 ESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKC 137
Query: 139 ENIMVDESLCNIKIIDFGSA-VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWS 197
EN ++ N+K+ DFG A V ++E GS APEV Q + ++ D+WS
Sbjct: 138 ENALLQG--FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWS 195
Query: 198 LGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISI---DLCMKLLS 248
+G++++ F++++ P W+ K V+F PT L+IS DL +LL
Sbjct: 196 MGVVLYVMLCASLPFDDTDIPKMLWQQQK--GVSF------PTHLSISADCQDLLKRLLE 247
Query: 249 VDVKQRLSIQDV 260
D+ R SI++V
Sbjct: 248 PDMILRPSIEEV 259
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 73.6 bits (179), Expect = 3e-13
Identities = 61/217 (28%), Positives = 99/217 (45%), Gaps = 13/217 (5%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTV----LYLMKMSMLPTFEERALWFC 117
+E E+L LNH II+ + + H + V L L+K +E F
Sbjct: 59 REIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFH 118
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAV----DVGPNKEACHGIRG 173
Q+ I Y H ++VHRDLK +N+++D+ NIK+ DF + D G
Sbjct: 119 QLSLAIKYCHDLDVVHRDLKCDNLLLDKDF-NIKLSDFSFSKRCLRDDSGRMALSKTFCG 177
Query: 174 SEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNP 233
S APEV Q + Y+ D+WSLG++++ S P I K+ + E P
Sbjct: 178 SPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGS-MPYDDSNIKKMLRIQKEHRVNFP 236
Query: 234 TTLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+ +++ DL +L DV +RL I ++++ + Q
Sbjct: 237 RSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQ 273
>CE17343 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 73.6 bits (179), Expect = 3e-13
Identities = 50/150 (33%), Positives = 78/150 (51%), Gaps = 5/150 (3%)
Query: 57 KEVCVKEYELLKKLNHKCIIEALDC-NKRKHTITFPYYSYTVLYLMKMSMLPTFEER--A 113
K+ +E E++K L H I + + + H I Y L KM + +E
Sbjct: 113 KKFLPREKEIVKLLKHDNICRLYEMISFQDHIIFVNEYCAGGDLLRKMKDIVAMKEEDAK 172
Query: 114 LWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRG 173
F Q+ + +L S+NIVHRDLK ENI +D+ N+K+ DFG + + P E G
Sbjct: 173 FTFRQLIAALTHLQSYNIVHRDLKCENIFMDKH-GNVKLGDFGFSRILKPG-EKSGTFCG 230
Query: 174 SEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
S +APE+F+ +Y G VD+WS G++++
Sbjct: 231 SRAYVAPEIFRGREYSGNAVDVWSTGVILY 260
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 73.6 bits (179), Expect = 3e-13
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 15/162 (9%)
Query: 115 WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG--SAVDVGPNKEACHGIR 172
+F Q+ + + HS + HRD+K EN+++D++ N+K+ DFG + D H
Sbjct: 114 YFYQLINAVDFCHSREVYHRDIKPENLLLDDNE-NLKVSDFGLSALADCKRQDGLLHTTC 172
Query: 173 GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAF 226
G+ +APEV R Y+GT D+WS G+++F F++SN KI K D A
Sbjct: 173 GTPAYVAPEVINRKGYDGTKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAP 232
Query: 227 EAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+ L LC K+L + + R++I + S+F++
Sbjct: 233 SWFAPEVRRL-----LC-KMLDPNPETRITIARIRESSWFRK 268
>At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 545
Score = 73.6 bits (179), Expect = 3e-13
Identities = 57/199 (28%), Positives = 99/199 (49%), Gaps = 23/199 (11%)
Query: 25 QGTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALD-CNK 83
+GT C E+ A+K + L + ++ +E +++K+ HK +++ + C K
Sbjct: 294 KGTYCSQEV---------AIKVLKPERLDSDLEKEFAQEVFIMRKVRHKNVVQFIGACTK 344
Query: 84 RKHTITFPYYS-----YTVLYLMK-MSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLK 137
H + Y L+ K + LPT + A+ IC+G++YLH +NI+HRDLK
Sbjct: 345 PPHLCIVTEFMPGGSVYDYLHKQKGVFKLPTLFKVAI---DICKGMSYLHQNNIIHRDLK 401
Query: 138 LENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWS 197
N+++DE+ +K+ DFG A V G+ + MAPEV + Y+ D++S
Sbjct: 402 AANLLMDENEV-VKVADFGVA-RVKAQTGVMTAETGTYRWMAPEVIEHKPYD-HKADVFS 458
Query: 198 LGIMMFEFFNNSN-KPAFP 215
GI+++E +P P
Sbjct: 459 YGIVLWELLTGKGLRPTIP 477
>At3g51630 [R] KOG0584 Serine/threonine protein kinase
Length = 547
Score = 73.6 bits (179), Expect = 3e-13
Identities = 62/216 (28%), Positives = 102/216 (46%), Gaps = 20/216 (9%)
Query: 63 EYELLKKLNHKCIIEA----LDCNKRKHT-ITFPYYSYTVLYLMKMSMLPTFEERALWFC 117
E LLK LNH+ II +D N+R IT + S T+ + W
Sbjct: 72 EVHLLKNLNHESIIRYCTSWIDVNRRTFNFITELFTSGTLREYRRKYQKVDIRAIKSWAR 131
Query: 118 QICEGIAYLHSHN--IVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSE 175
QI G+AYLH H+ ++HRDLK +NI V+ L +KI D G A + ++ A H + G+
Sbjct: 132 QILNGLAYLHGHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLAAILRGSQNA-HSVIGTP 190
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAY 229
+ MAPE+++ E VD++S G+ + E ++ PA +K + +
Sbjct: 191 EFMAPELYEEDYNE--LVDIYSFGMCVLEMLTGEYPYSECTNPAQIYKKVTSGKLPDSFH 248
Query: 230 TKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSF 265
T + C++ +S +RL ++++ D F
Sbjct: 249 LIQHTEAQRFVGKCLETVS----RRLPAKELLADPF 280
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 73.6 bits (179), Expect = 3e-13
Identities = 70/261 (26%), Positives = 123/261 (46%), Gaps = 24/261 (9%)
Query: 25 QGTTCEVEIVSKSD-GSKLALKKFRSWDLHNHHK-EVCVKEYELLKKLNHKCIIEALD-- 80
+GT +V+ S+ G +ALK + H E +E +K + H +++ +
Sbjct: 22 EGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPNVVQLYEVM 81
Query: 81 CNKRKHTITFPYYSYTVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKL 138
+K K I Y + L+ ++ + E R +F Q+ + Y HS + HRDLK
Sbjct: 82 ASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARR-YFQQLIHAVDYCHSRGVYHRDLKP 140
Query: 139 ENIMVDESLCNIKIIDFG-SAVDVGPNKEA-CHGIRGSEQLMAPEVFQRLKYEGTPVDMW 196
EN+++D S N+KI DFG SA+ + H G+ +APEV Y+G DMW
Sbjct: 141 ENLLLD-SYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYDGATADMW 199
Query: 197 SLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNI-SIDLCMKLLSV 249
S G++++ F++SN KI F P L++ ++ L ++L
Sbjct: 200 SCGVVLYVLLAGYLPFDDSNLMNL---YKKISSGEFNC----PPWLSLGAMKLITRILDP 252
Query: 250 DVKQRLSIQDVINDSFFQENH 270
+ R++ Q+V D +F++++
Sbjct: 253 NPMTRVTPQEVFEDEWFKKDY 273
>At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 366
Score = 73.6 bits (179), Expect = 3e-13
Identities = 56/203 (27%), Positives = 100/203 (48%), Gaps = 21/203 (10%)
Query: 32 EIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFP 91
+++ + ALK +++C +E E+L+ +NH +++ + + I
Sbjct: 95 KVIHRPSSRLYALKVIYGNHEETVRRQIC-REIEILRDVNHPNVVKCHEMFDQNGEIQ-- 151
Query: 92 YYSYTVLYLMKMSMLP---TFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVDES 146
+L M L ++E+ L QI G+AYLHS +IVHRD+K N++++ S
Sbjct: 152 ----VLLEFMDKGSLEGAHVWKEQQLADLSRQILSGLAYLHSRHIVHRDIKPSNLLIN-S 206
Query: 147 LCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPE----VFQRLKYEGTPVDMWSLGIMM 202
N+KI DFG + + + C+ G+ M+PE + KY+G D+WSLG+ +
Sbjct: 207 AKNVKIADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNQGKYDGYAGDIWSLGVSI 266
Query: 203 FEFFNNSNKPAFPWKIAKIDDVA 225
EF+ FP+ +++ D A
Sbjct: 267 LEFYLG----RFPFPVSRQGDWA 285
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 73.6 bits (179), Expect = 3e-13
Identities = 48/156 (30%), Positives = 82/156 (51%), Gaps = 7/156 (4%)
Query: 53 HNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLY--LMKMSMLPT 108
H+ K++ +E +++ +L+H+ +I D + + + + S L+ + + T
Sbjct: 6173 HSVEKDLIRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMT 6232
Query: 109 FEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVD-ESLCNIKIIDFGSAVDVGPNKEA 167
E + QICEGI ++H NI+H D+K ENIM S N+K+IDFG A + PN E
Sbjct: 6233 EAEVINYMRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPN-EV 6291
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
G+ + APE+ R + G DMW+ G++ +
Sbjct: 6292 VKITTGTAEFAAPEIVNR-EPVGFYTDMWATGVLSY 6326
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 73.2 bits (178), Expect = 4e-13
Identities = 71/274 (25%), Positives = 119/274 (42%), Gaps = 52/274 (18%)
Query: 35 SKSDGSKLALK----KFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI-- 88
S G +A+K KF SWD + + ++E + LKKLNH +I+ + + +
Sbjct: 23 SNESGELVAIKRMKRKFYSWD-----ECMNLREVKSLKKLNHANVIKLKEVIRENDHLYF 77
Query: 89 TFPYYSYTVLYLMK--MSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDE 145
F Y + LMK + P R + + QI +G+A++H H HRD+K EN++ +
Sbjct: 78 IFEYMKENLYQLMKDRNKLFPESVIRNIMY-QILQGLAFIHKHGFFHRDMKPENLLCMGP 136
Query: 146 SLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF 205
L +KI DFG A ++ + + APEV R +P+D+W++G +M E
Sbjct: 137 EL--VKIADFGLARELRSQPPYTDYV-STRWYRAPEVLLRSSVYSSPIDVWAVGSIMAEL 193
Query: 206 FNNSNKPAFP--------WKIAKI------------------------DDVAFEAYTKNP 233
+ +P FP +KI ++ V T P
Sbjct: 194 Y--MLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIP 251
Query: 234 TTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
N +I L ++L+ D K+R + + +FQ
Sbjct: 252 NASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 73.2 bits (178), Expect = 4e-13
Identities = 60/221 (27%), Positives = 104/221 (46%), Gaps = 21/221 (9%)
Query: 63 EYELLKKLNHK--CIIEALDCNKRKHTITFPYYSYTVL--YLMKMSMLPTFEERALWFCQ 118
E + L+ L+H+ C + + K I Y S + Y+++ L E R +F Q
Sbjct: 57 EMDALRNLSHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARH-FFRQ 115
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIR---GSE 175
+ IA++HS HRDLK EN+++ E L ++K+IDFG + H + GS
Sbjct: 116 LVSAIAFVHSQGYAHRDLKPENLLLTEDL-HLKLIDFGLCAKTEKGRIDKHNLDTCCGSP 174
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAY 229
APE+ Q L+Y+G D+WS+GI+++ F + N KI +E
Sbjct: 175 AYAAPELIQGLQYKGNEADVWSMGILLYTLLVGALPFEDDNMQIMYKKIQ--SGCFYEPE 232
Query: 230 TKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+P +S L +L V ++R+S++ ++ + +
Sbjct: 233 FLSP----LSKQLLRAMLQVVPERRISVKKLLEHDWLNHKY 269
>CE03080 [R] KOG0584 Serine/threonine protein kinase
Length = 1851
Score = 73.2 bits (178), Expect = 4e-13
Identities = 59/223 (26%), Positives = 110/223 (48%), Gaps = 23/223 (10%)
Query: 62 KEYELLKKLNHKCIIEALD-------CNKRKHTI--TFPYYSYTV-LYLMKMSMLPTFEE 111
+E E+LK L H I+ D C KRK+ + T S T+ +YL + +
Sbjct: 390 EEAEMLKDLQHPNIVRFYDYWESADLCGKRKYIVLVTELMTSGTLKMYLKRFKRINIKVV 449
Query: 112 RALWFCQICEGIAYLHSHN--IVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACH 169
W QI +G+++LH+ N ++HRDLK +NI + + ++KI D G A NK
Sbjct: 450 LKSWCRQILKGLSFLHTRNPPVIHRDLKCDNIFITGTTGSVKIGDLGLA--TLKNKSFAK 507
Query: 170 GIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDD 223
+ G+ + MAPE+++ + E VD+++ G+ + E ++ PA ++ I
Sbjct: 508 SVIGTPEFMAPEMYEEMYDES--VDVYAFGMCLLEMVTGEYPYSECMNPATIYR-KVISG 564
Query: 224 VAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFF 266
V E +++ P ++ + + V ++R +++ ++ D FF
Sbjct: 565 VKPECFSRIPAQYPEIREIIDRCIRVRREERSTVKQLLVDDFF 607
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 73.2 bits (178), Expect = 4e-13
Identities = 62/222 (27%), Positives = 103/222 (45%), Gaps = 19/222 (8%)
Query: 62 KEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLY-LMKMSMLPTFEERALWFCQ 118
+E +K LNH I++ + K K I Y S L + + + R L F Q
Sbjct: 59 REIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKL-FQQ 117
Query: 119 ICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLM 178
+ + + Y H+ + HRDLK +N+++D S N+K+ DFG + V + + GS +
Sbjct: 118 LIDAVDYCHNRGVYHRDLKPQNLLLD-SKGNLKVSDFGLSA-VPKSGDMLSTACGSPCYI 175
Query: 179 APEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKN 232
APE+ Y G VD+WS G+++FE F++ P KI + D YT
Sbjct: 176 APELIMNKGYSGAAVDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRAD------YTFP 229
Query: 233 PTTLNISIDLCMKLLSVDVKQRLSIQD-VINDSFFQENHNSV 273
P L +L + R+++ + +I DS+F+ + V
Sbjct: 230 PGFTGEQKRLIFNILDPNPLSRITLAEIIIKDSWFKIGYTPV 271
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 73.2 bits (178), Expect = 4e-13
Identities = 57/218 (26%), Positives = 98/218 (44%), Gaps = 19/218 (8%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALW--FCQI 119
+E +++ H ++E + K I F L +E W F Q+
Sbjct: 59 REISVMRIAKHPNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGKLKEDVAWKYFYQL 118
Query: 120 CEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG--SAVDVGPNKEACHGIRGSEQL 177
+ + HS + HRD+K EN+++D++ N+K+ DFG + D H G+
Sbjct: 119 ISAVDFCHSRGVYHRDIKPENLLLDDN-DNLKVSDFGLSALADCKRQDGLLHTTCGTPAY 177
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTK 231
+APEV R YEGT D+WS G+++F F+++N KI K D K
Sbjct: 178 VAPEVINRKGYEGTKADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKIGKAD-------FK 230
Query: 232 NPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQE 268
P+ + L K+L + + R++I + S+F++
Sbjct: 231 CPSWFAPEVKRLLCKMLDPNHETRITIAKIKESSWFRK 268
>At2g30040 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 463
Score = 73.2 bits (178), Expect = 4e-13
Identities = 52/170 (30%), Positives = 87/170 (50%), Gaps = 15/170 (8%)
Query: 108 TFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEA 167
T R +W + ++++HS+ IVH D+K +N++V ++K+ DFGSAV+ K
Sbjct: 115 TLLRRYVWC--LVSALSHVHSNGIVHCDVKSKNVLVFNGGSSVKLADFGSAVEF--EKST 170
Query: 168 CH-GIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAF 226
H RGS MAPEV +R +Y+G D+WSLG + E + KPA W+ D ++
Sbjct: 171 IHVSPRGSPLWMAPEVVRR-EYQGPESDVWSLGCTVIEML--TGKPA--WEDHGFDSLSR 225
Query: 227 EAYTKNPTTLNISI-----DLCMKLLSVDVKQRLSIQDVINDSFFQENHN 271
++ + + + + D K L D QR S ++ F ++H+
Sbjct: 226 IGFSNDLPFIPVGLSELGRDFLEKCLKRDRSQRWSCDQLLQHPFLCQDHH 275
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 72.8 bits (177), Expect = 6e-13
Identities = 68/248 (27%), Positives = 114/248 (45%), Gaps = 18/248 (7%)
Query: 34 VSKSDGSKLALKKF------RSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRK-H 86
++ S G +A+K+ S D H + E LL++L+H+ I++ L N H
Sbjct: 115 MNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDH 174
Query: 87 TITFPYYSYTVLYLMKMSMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENIMVD 144
F Y ++M +FEE + + Q +G+ YLHS IVHRD+K NI+VD
Sbjct: 175 LNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVD 234
Query: 145 ESLCNIKIIDFGSAVDVGPNKE------ACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSL 198
IKI DFG + + N A +GS MAPEV ++ + D+WSL
Sbjct: 235 NK-GKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTMHT-EKTDIWSL 292
Query: 199 GIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNIS-IDLCMKLLSVDVKQRLSI 257
G ++ E + + ++ I + + P+ ++ S ID K ++D R +
Sbjct: 293 GCLVIEMLTSKHPYPNCDQMQAIFRIGENILPEFPSNISSSAIDFLEKTFAIDCNLRPTA 352
Query: 258 QDVINDSF 265
++++ F
Sbjct: 353 SELLSHPF 360
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 72.8 bits (177), Expect = 6e-13
Identities = 65/249 (26%), Positives = 120/249 (48%), Gaps = 35/249 (14%)
Query: 57 KEVCVKEYELLKKLNHKCII---EALDCNKRKHTITFPYYSYTVLY--LMKMSMLPTFEE 111
KE + E ++ +L+H+ ++ EA D I + S L+ +++ L + EE
Sbjct: 234 KENVIHEISMMNQLHHEKLLNLHEAFDMGNEMWLIE-EFVSGGELFEKILEDDSLMSEEE 292
Query: 112 RALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN-IKIIDFGSAVDVGPNKEACHG 170
+ QI G++++H + IVH DLK ENI++ N +KIIDFG A + P K++
Sbjct: 293 VRDYMHQILLGVSHMHKNQIVHLDLKPENILLKAKNSNELKIIDFGLARKLDP-KKSVKL 351
Query: 171 IRGSEQLMAPEVFQRLKYE--GTPVDMWSLGIMMFEFFNN-------------SNKPAFP 215
+ G+ + APEV + Y+ G DMW++G++ + + +N A
Sbjct: 352 LFGTPEFCAPEV---VNYQPVGLSTDMWTVGVISYVLLSGLSPFLGDSDEDTLANVSASD 408
Query: 216 WKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDG 275
W DD +++ + +++ D +L+ D ++R+S+QD + + + +D
Sbjct: 409 W---DFDDPSWDDVS------DLAKDFICRLMIKDKRKRMSVQDALRHPWITKMQPKLDK 459
Query: 276 VSAHARTKR 284
AR KR
Sbjct: 460 SGVPARQKR 468
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/223 (25%), Positives = 105/223 (46%), Gaps = 19/223 (8%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITF--PYYSYTVLYLMKMSMLPTFEERALWFCQI 119
+E +L+++ H I++ + K I F Y L+ E +F Q+
Sbjct: 73 REISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQL 132
Query: 120 CEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG-SAVDVGPNKEAC-HGIRGSEQL 177
+ + H+ + HRDLK EN+++DE+ N+K+ DFG SAV ++ H G+
Sbjct: 133 ISAVTFCHARGVYHRDLKPENLLLDEN-GNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAY 191
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTK 231
+APEV R Y+ VD+WS G+++F F++ N A KI + +
Sbjct: 192 VAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKI-------YRGEFR 244
Query: 232 NPTTLNISID-LCMKLLSVDVKQRLSIQDVINDSFFQENHNSV 273
P + + L KLL + ++R + +++ +S+F++ +
Sbjct: 245 CPRWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFKKGFKHI 287
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 72.8 bits (177), Expect = 6e-13
Identities = 68/243 (27%), Positives = 112/243 (45%), Gaps = 23/243 (9%)
Query: 25 QGTTCEVEIVSKSDGSKLALKKFRSWD--LHNHHKEVCVKEYELLKKLNHKCIIEALDCN 82
QG +V V K D S++ K D + +H E E ++L K++H I++
Sbjct: 148 QGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIVQL---- 203
Query: 83 KRKHTITFPYYSYTVLYLMKMSML-------PTFEE--RALWFCQICEGIAYLHSHNIVH 133
K++ Y Y VL + L F E ++ +I +++LH I+H
Sbjct: 204 --KYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMH 261
Query: 134 RDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPV 193
RDLK ENI++D ++ + DFG A + N + + + G+ + MAPE+ R K
Sbjct: 262 RDLKPENILMDVD-GHVMLTDFGLAKEFEENTRS-NSMCGTTEYMAPEIV-RGKGHDKAA 318
Query: 194 DMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMK-LLSVDVK 252
D WS+GI+++E + KP F KI + K P L+ +K LL + +
Sbjct: 319 DWWSVGILLYEML--TGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPE 376
Query: 253 QRL 255
+RL
Sbjct: 377 RRL 379
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 72.4 bits (176), Expect = 7e-13
Identities = 51/157 (32%), Positives = 83/157 (52%), Gaps = 12/157 (7%)
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
++C + YLHS +I++RDLK ENI++D++ +IKI DFG A V + + + G+
Sbjct: 193 EVCLALEYLHSKDIIYRDLKPENILLDKN-GHIKITDFGFAKYV---PDVTYTLCGTPDY 248
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLN 237
+APEV Y + +D WS GI+++E P + K + A + P N
Sbjct: 249 IAPEVVSTKPYNKS-IDWWSFGILIYEMLAGYT-PFYDSNTMKTYEKILNAELRFPPFFN 306
Query: 238 ISI-DLCMKLLSVDVKQRL-----SIQDVINDSFFQE 268
+ DL +L++ D+ QRL +DV N +F+E
Sbjct: 307 EDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKE 343
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 72.4 bits (176), Expect = 7e-13
Identities = 59/195 (30%), Positives = 95/195 (48%), Gaps = 30/195 (15%)
Query: 35 SKSDGSKLALKK----FRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF 90
S G +A+KK F SW+ + + ++E + LKKLNH ++ K K I
Sbjct: 23 SIESGELIAIKKMKRKFYSWE-----ECMNLREVKSLKKLNHANVV------KLKEVIRE 71
Query: 91 PYYSYTVLYLMKMSMLPTFEERALWF---------CQICEGIAYLHSHNIVHRDLKLENI 141
+ Y + MK ++ +ER F QI +G+A++H H HRDLK EN+
Sbjct: 72 NDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENL 131
Query: 142 M-VDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGI 200
+ + L +KI DFG A ++ +K + APEV R +P+D+W++G
Sbjct: 132 LCMGPEL--VKIADFGLAREI-RSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGC 188
Query: 201 MMFEFFNNSNKPAFP 215
+M E + + +P FP
Sbjct: 189 IMAEVY--TLRPLFP 201
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 72.4 bits (176), Expect = 7e-13
Identities = 54/175 (30%), Positives = 81/175 (45%), Gaps = 20/175 (11%)
Query: 115 WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGS 174
+F QI I+Y H ++VHRDLK EN++ E +K+ DFG + P K+ GS
Sbjct: 119 YFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSC-GS 177
Query: 175 EQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEA 228
APE+ +Y+ VD+WSLG+++F F +N + I D
Sbjct: 178 LAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSE---TLTMIMDC---K 231
Query: 229 YTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHARTK 283
YT DL ++L D K+R S++++ ENH + GV TK
Sbjct: 232 YTVPSHVSKECKDLITRMLQRDPKRRASLEEI-------ENHPWLQGVDPSPATK 279
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 72.4 bits (176), Expect = 7e-13
Identities = 52/177 (29%), Positives = 83/177 (46%), Gaps = 14/177 (7%)
Query: 38 DGSKLALKKFRSWDLHNHHKEV-CVKEYELLKKLNHKCII-------EALDCNKRKHTIT 89
DG +ALKK + +DL + C+KE +LLK+LNH +I E + N
Sbjct: 56 DGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELAD 115
Query: 90 FPYYSYTVLYLMKMSMLPTFEERALW--FCQICEGIAYLHSHNIVHRDLKLENIMVDESL 147
S + + K L ER +W F Q+C + ++HS ++HRD+K N+ + +
Sbjct: 116 AGDLSRMIKHFKKQKRL--IPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATG 173
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
+K+ D G A H + G+ M+PE Y D+WSLG +++E
Sbjct: 174 V-VKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGY-NFKSDIWSLGCLLYE 228
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 72.4 bits (176), Expect = 7e-13
Identities = 61/194 (31%), Positives = 90/194 (45%), Gaps = 32/194 (16%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCV-----KEYELLKKLNHKCIIEALDCNKRKHTITF 90
KSD S +A+K+ + + + E E++KKL+H I+ DC IT
Sbjct: 189 KSDRSVVAIKQLNTQFSTRCSRAIAKTRDIQNEVEVMKKLSHPNIVAIYDC------ITV 242
Query: 91 PYYSYTVLYLM------------KMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLK 137
YSY V+ + K + + E +F Q+ + + YLHS I HRD+K
Sbjct: 243 AKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKYFAFQLIDAVLYLHSVGICHRDIK 302
Query: 138 LENIMVDESL--CNIKIIDFGSAVD-VGPNKEACHGIRGSEQLMAPEVFQRLKYEGTP-V 193
ENI+ C +K+ DFG A + V K C G+ APE+ E TP V
Sbjct: 303 PENILCSNKAERCILKLTDFGMAKNSVNRMKTHC----GTPSYCAPEIVANQGVEYTPKV 358
Query: 194 DMWSLGIMMFEFFN 207
D+WSLG ++F F+
Sbjct: 359 DIWSLGCVLFITFS 372
>At5g58350 [R] KOG0584 Serine/threonine protein kinase
Length = 571
Score = 72.4 bits (176), Expect = 7e-13
Identities = 68/242 (28%), Positives = 108/242 (44%), Gaps = 22/242 (9%)
Query: 63 EYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYT--VLYLMKMSMLPTFEERAL--WF 116
E LL LNHK II + HT+ F +T L K L + RA+ W
Sbjct: 68 EVHLLSTLNHKSIIRFYTSWIDVHNHTLNFITELFTSGTLRQYKNKYL-RIDIRAIKSWA 126
Query: 117 CQICEGIAYLHSHN--IVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGS 174
QI EG+ YLH H+ ++HRDLK +NI V+ L +KI D G A + + + H I G+
Sbjct: 127 RQILEGLVYLHEHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLA-RMLRDCHSAHSIIGT 185
Query: 175 EQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEA 228
+ MAPE+++ E +D++S G+ E ++ N PA +K +
Sbjct: 186 PEFMAPELYEENYNE--LIDVYSFGMCFLEMITSEFPYSECNHPAQIYKKVVGGKLPGAF 243
Query: 229 YTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHARTKRILER 288
Y I C+ V +R+S ++++ D F + + + S K L
Sbjct: 244 YRVGDIEAQRFIGKCL----VSASKRVSAKELLQDPFLASDESWMVYTSGAGNPKPFLNE 299
Query: 289 SQ 290
++
Sbjct: 300 NE 301
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 72.4 bits (176), Expect = 7e-13
Identities = 62/221 (28%), Positives = 105/221 (47%), Gaps = 17/221 (7%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITF--PYYSYTVLYLMKMSMLPTFEERALWFCQI 119
+E +++ + H I+E + K I F Y L+ + + +F Q+
Sbjct: 62 REISIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGKLKEDSARKYFQQL 121
Query: 120 CEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG-SAVDVGPNKEA-CHGIRGSEQL 177
+ + HS + HRDLK EN++VDE+ ++K+ DFG SA+ ++ H G+
Sbjct: 122 ISAVDFCHSRGVSHRDLKPENLLVDEN-GDLKVSDFGLSALPEQILQDGLLHTQCGTPAY 180
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTK 231
+APEV ++ Y+G D+WS GI+++ F + N KI K + +
Sbjct: 181 VAPEVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSE------FEY 234
Query: 232 NPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNS 272
P S L KLL VD +R+SI ++ +F++N NS
Sbjct: 235 PPWFSPESKRLISKLLVVDPNKRISIPAIMRTPWFRKNINS 275
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 72.4 bits (176), Expect = 7e-13
Identities = 73/263 (27%), Positives = 124/263 (46%), Gaps = 21/263 (7%)
Query: 21 PRLIQGTTCEVEIVS-KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCII--- 76
PR+ G+ V + +S G ++A+K+ L ++ +KE +L ++H II
Sbjct: 14 PRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNIIRFY 73
Query: 77 EALDCNKRKHTITFPYYSYTVL--YLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVH 133
EA++ R + Y S L Y+ + +P E A F Q+ G+ L + +H
Sbjct: 74 EAIETGDRIFLV-LEYCSGGDLAGYINRHGKVP--EAVAKHFMRQLALGLQVLQEKHFIH 130
Query: 134 RDLKLENIMVD--ESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGT 191
RDLK +N+++ E +KI DFG A + P A GS MAPE+ + KY+
Sbjct: 131 RDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPESMA-ETFCGSPLYMAPEIIRNQKYD-A 188
Query: 192 PVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMK 245
D+WS G ++F+ F+ +N I + ++ F T+N + +DLC
Sbjct: 189 KADLWSAGAILFQLVTGKPPFDGNNHIQLFHNIVRDTELKFPEDTRNEIHPD-CVDLCRS 247
Query: 246 LLSVDVKQRLSIQDVINDSFFQE 268
LL + +RL+ ++ N F +E
Sbjct: 248 LLRRNPIERLTFREFFNHMFLRE 270
>At2g23030 [T] KOG0583 Serine/threonine protein kinase
Length = 339
Score = 72.4 bits (176), Expect = 7e-13
Identities = 55/171 (32%), Positives = 84/171 (48%), Gaps = 18/171 (10%)
Query: 111 ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC-NIKIIDFG----SAVDVGPNK 165
E +F Q+ G+ YLH+ I HRDLKLEN ++D S +KI DFG S + P
Sbjct: 99 EARYFFQQLICGVHYLHALQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSNPKS 158
Query: 166 EACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS---NKPAFPWKIAKID 222
G+ +APEVF R +Y+G VD+WS G+ ++ + P P K
Sbjct: 159 TV-----GTPAYIAPEVFCRSEYDGKSVDVWSCGVALYVMLVGAYPFEDPKDPRNFRKTV 213
Query: 223 DVAFEAYTKNPTTLNISIDLCMKLLS----VDVKQRLSIQDVINDSFFQEN 269
K P ++IS D C KLLS + R +++++ + ++F +N
Sbjct: 214 QKIMAVNYKIPGYVHISED-CRKLLSRIFVANPLHRSTLKEIKSHAWFLKN 263
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 72.4 bits (176), Expect = 7e-13
Identities = 52/168 (30%), Positives = 83/168 (48%), Gaps = 10/168 (5%)
Query: 110 EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC-NIKIIDFGSAVDVGPNKEAC 168
+E +F Q+ G+ Y HS I HRDLKLEN ++D S +KI DFG + G
Sbjct: 98 DEARFFFQQLISGVNYCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSKS-GVLHSQP 156
Query: 169 HGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS---NKPAFPWKIAKIDDVA 225
G+ +APEV +Y+G D+WS G+ ++ + P+ P K
Sbjct: 157 KTTVGTPAYIAPEVLSTKEYDGKIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIGRI 216
Query: 226 FEAYTKNPTTLNISIDLCMKLLS----VDVKQRLSIQDVINDSFFQEN 269
+A P + +S D C LLS + ++R++I+++ N S+F +N
Sbjct: 217 LKAQYAIPDYVRVS-DECRHLLSRIFVANPEKRITIEEIKNHSWFLKN 263
>7300413 [T] KOG0583 Serine/threonine protein kinase
Length = 302
Score = 72.4 bits (176), Expect = 7e-13
Identities = 52/153 (33%), Positives = 78/153 (49%), Gaps = 9/153 (5%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYT----VLYLMKMSMLPTFEERALWFC 117
+E E+L K++H II+ +R I F + Y +L +K S ++ +WF
Sbjct: 78 RELEILTKIDHSNIIQIHSILQRGPKI-FIFMRYAENGDLLSHIKRSGPIDEKQSKIWFF 136
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA---VDVGPNKEACHGIRGS 174
Q+ + + YLH+ +I HRDLK ENI++ + L NIK+ DFG A D + GS
Sbjct: 137 QMSKALKYLHNLDIAHRDLKCENILLSKRL-NIKLADFGFARYCRDDNGREMKSETYCGS 195
Query: 175 EQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFN 207
APEV Y+ D WSLG+++F N
Sbjct: 196 AAYAAPEVVCGRPYDPKLADAWSLGVILFIMMN 228
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 72.4 bits (176), Expect = 7e-13
Identities = 67/296 (22%), Positives = 122/296 (40%), Gaps = 51/296 (17%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC---N 82
G C+ V + +K+A+KK H + +E LLK ++H+ +I LD
Sbjct: 36 GQVCKA--VVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPG 93
Query: 83 KRKHTITFPYYSYTVLYLMKMSMLPTFEERAL-------WFCQICEGIAYLHSHNIVHRD 135
+ ++ Y V +LM + + L QI G+ Y+HS ++HRD
Sbjct: 94 QPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRD 153
Query: 136 LKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDM 195
LK NI V+E C ++I+DFG A P + G + APE+ + D+
Sbjct: 154 LKPSNIAVNED-CELRILDFGLA---RPAESEMTGYVATRWYRAPEIMLNWMHYNQTADI 209
Query: 196 WSLGIMMFEFFNNSNKPAFPWK--------------------IAKIDDVAFEAYTKNPTT 235
WS+G +M E + + FP +++I + Y ++
Sbjct: 210 WSVGCIMAELL--TGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPV 267
Query: 236 L-------------NISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSA 278
+ ++IDL K+L +D +R++ + + + ++ H+ D +A
Sbjct: 268 MPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTA 323
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 72.0 bits (175), Expect = 9e-13
Identities = 63/250 (25%), Positives = 113/250 (45%), Gaps = 27/250 (10%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKE-VCVKEYELLKKLNHKCIIEALDCNKR 84
G C ++ ++ G A K+ + E + + E ++L+K+N + ++ +
Sbjct: 198 GEVCACQV--RATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFVVNLAYAYET 255
Query: 85 KHTI----TFPYYSYTVLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLE 139
K + T ++ M EERAL++ +I G+ LH N V+RDLK E
Sbjct: 256 KDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRENTVYRDLKPE 315
Query: 140 NIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLG 199
NI++D+ +I+I D G AV + P + G G+ MAPEV +Y G D W LG
Sbjct: 316 NILLDD-YGHIRISDLGLAVKI-PEGDLIRGRVGTVGYMAPEVLNNQRY-GLSPDYWGLG 372
Query: 200 IMMFEFFNNSN----------KPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSV 249
+++E + + ++ + ++V +++ + +C LL+
Sbjct: 373 CLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKS------ICKMLLTK 426
Query: 250 DVKQRLSIQD 259
D KQRL Q+
Sbjct: 427 DAKQRLGCQE 436
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 72.0 bits (175), Expect = 9e-13
Identities = 52/188 (27%), Positives = 96/188 (50%), Gaps = 10/188 (5%)
Query: 35 SKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPY 92
++ G +A+KKF + K++ ++E +LK+L H ++ L+ +RK + F Y
Sbjct: 24 NRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEY 83
Query: 93 YSYTVLYLMKMSM--LPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNI 150
+TVL+ + +P +++ + Q + + + H HN +HRD+K ENI++ + I
Sbjct: 84 CDHTVLHELDRYQRGVPEHLVKSITW-QTLQAVNFCHKHNCIHRDVKPENILITKHSV-I 141
Query: 151 KIIDFGSA-VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS 209
K+ DFG A + GP+ + + +PE+ G PVD+W++G + E S
Sbjct: 142 KLCDFGFARLLTGPSDYYTDYV-ATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELL--S 198
Query: 210 NKPAFPWK 217
P +P K
Sbjct: 199 GVPLWPGK 206
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 72.0 bits (175), Expect = 9e-13
Identities = 67/253 (26%), Positives = 108/253 (42%), Gaps = 26/253 (10%)
Query: 32 EIVSKSDGSKLALKKF-RSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF 90
E GS A+K +S H +E + E EL + L H+ I+ + H
Sbjct: 39 EATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIV------RFSHHFED 92
Query: 91 PYYSYTVLYLMKMSMLPTF---------EERALWFCQICEGIAYLHSHNIVHRDLKLENI 141
Y L L L E + QI G+ YLH I+HRDLKL N
Sbjct: 93 ADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNF 152
Query: 142 MVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIM 201
+ E++ +K+ DFG A + P ++ I G+ +APEV R + G D+WSLG +
Sbjct: 153 FITENM-ELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLR-QGHGPEADVWSLGCV 210
Query: 202 MFEFFNNSNKPAFPWKIAKIDDV---AFEAYTKNPTTLNI-SIDLCMKLLSVDVKQRLSI 257
M+ S P++ A + + + + P +L++ + L +L + R SI
Sbjct: 211 MYTLLCGSP----PFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSI 266
Query: 258 QDVINDSFFQENH 270
++ FF + +
Sbjct: 267 DQILRHDFFTKGY 279
>CE27410 [T] KOG0583 Serine/threonine protein kinase
Length = 617
Score = 72.0 bits (175), Expect = 9e-13
Identities = 60/242 (24%), Positives = 109/242 (44%), Gaps = 21/242 (8%)
Query: 63 EYELLKKLNHKCIIEALDC----NKRKHTITFPYYSYTVLYLMKMSMLP--TFEERALWF 116
E +L+++NH+ +I+ ++ K K + F Y +V L+ M T E F
Sbjct: 232 EMSILRRMNHRNVIKLIEIFNIPAKGKVYMVFEYCIGSVQQLLDMEPARRLTIGESHAIF 291
Query: 117 CQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA--VDVGPNKEACHGIRGS 174
++C+G+ YLHS + H+D+K N++V +KI DFG A +++ C + G+
Sbjct: 292 IELCQGLNYLHSKRVSHKDIKPGNLLVSIDF-TVKICDFGVAEQINLFQRDGRCTKVNGT 350
Query: 175 EQLMAPEVF--QRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKN 232
+ PE ++G DMWS G+ ++ + P + + + E +
Sbjct: 351 PKFQPPECIYGNHDFFDGYKADMWSAGVTLYNLVSGKYPFEKPVLLKLYECIGTEP-LQM 409
Query: 233 PTTLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHARTKRILERS 289
PT + ++ DL KLL D +R + + + +F G+ RI+ER
Sbjct: 410 PTNVQLTKDLQDLLTKLLEKDFNERPTCLETMIHPWFLSTFPEDQGLG------RIMERM 463
Query: 290 QT 291
+T
Sbjct: 464 RT 465
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 72.0 bits (175), Expect = 9e-13
Identities = 52/187 (27%), Positives = 92/187 (48%), Gaps = 15/187 (8%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYL 100
++A+KK ++ H + ++E ++L + H+ II + R T+ Y V L
Sbjct: 121 RVAIKKISPFE-HQTFCQRTLREIKILNRFKHENIINIQEII-RSETVDSLKDIYIVQCL 178
Query: 101 MKMSMLPTFEERAL-------WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKII 153
M+ + + + L + QI G+ Y+HS N++HRDLK N++++ + C++KI
Sbjct: 179 METDLYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-TTCDLKIC 237
Query: 154 DFGSAVDVGPNKEACHGIR---GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSN 210
DFG A P + + + APE+ K +D+WS+G ++ E SN
Sbjct: 238 DFGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEML--SN 295
Query: 211 KPAFPWK 217
+P FP K
Sbjct: 296 RPLFPGK 302
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 72.0 bits (175), Expect = 9e-13
Identities = 41/96 (42%), Positives = 57/96 (58%), Gaps = 1/96 (1%)
Query: 114 LWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRG 173
L+ Q+ GI +LH HNIVHRD+K +N++VDES +KI DFGSA + N+ I
Sbjct: 137 LYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITYI-C 195
Query: 174 SEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS 209
S APE+ K T +D WS+G ++ E +NS
Sbjct: 196 SRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHNS 231
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 72.0 bits (175), Expect = 9e-13
Identities = 52/187 (27%), Positives = 92/187 (48%), Gaps = 15/187 (8%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYL 100
++A+KK ++ H + ++E ++L + H+ II + R T+ Y V L
Sbjct: 53 RVAIKKISPFE-HQTFCQRTLREIKILNRFKHENIINIQEII-RSETVDSLKDIYIVQCL 110
Query: 101 MKMSMLPTFEERAL-------WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKII 153
M+ + + + L + QI G+ Y+HS N++HRDLK N++++ + C++KI
Sbjct: 111 METDLYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-TTCDLKIC 169
Query: 154 DFGSAVDVGPNKEACHGIR---GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSN 210
DFG A P + + + APE+ K +D+WS+G ++ E SN
Sbjct: 170 DFGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEML--SN 227
Query: 211 KPAFPWK 217
+P FP K
Sbjct: 228 RPLFPGK 234
>At5g66880 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 72.0 bits (175), Expect = 9e-13
Identities = 49/167 (29%), Positives = 79/167 (46%), Gaps = 8/167 (4%)
Query: 110 EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC-NIKIIDFGSAVDVGPNKEAC 168
+E +F Q+ G++Y HS I HRDLKLEN ++D S +KI DFG + + +
Sbjct: 116 DEARFFFQQLLSGVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPK 175
Query: 169 HGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS---NKPAFPWKIAKIDDVA 225
+ G+ +APEV R +Y+G D+WS G+ ++ + P P K
Sbjct: 176 STV-GTPAYIAPEVLLRQEYDGKIADVWSCGVTLYVMLVGAYPFEDPEEPRDYRKTIQRI 234
Query: 226 FEAYTKNPTTLNISIDLC---MKLLSVDVKQRLSIQDVINDSFFQEN 269
P + IS + C ++ D R+SI ++ S+F +N
Sbjct: 235 LSVKYSIPDDIRISPECCHLISRIFVADPATRISIPEIKTHSWFLKN 281
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 72.0 bits (175), Expect = 9e-13
Identities = 72/263 (27%), Positives = 118/263 (44%), Gaps = 31/263 (11%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVK-EYELLKKLNHKCIIEALDCNKR 84
G C ++ ++ G A KK + E V E ++L+K+N ++ +
Sbjct: 321 GEVCACQV--RATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPFVVNLAYAYET 378
Query: 85 KHTI----TFPYYSYTVLYLMKMSMLPTFE-ERALWFC-QICEGIAYLHSHNIVHRDLKL 138
K + T ++ M P FE ERA ++ ++ G+ +LH IV+RD K
Sbjct: 379 KDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHKQGIVYRDCKP 438
Query: 139 ENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSL 198
ENI++D+ +++I D G AV++ P E G G+ MAPEV KY +P D +S
Sbjct: 439 ENILLDDH-GHVRISDLGLAVEI-PEGEMVRGRVGTVGYMAPEVIDNEKYAFSP-DWFSF 495
Query: 199 GIMMFEFFNNSNKPAFPWKIAK-------IDDVAFEAYTKNPTTLNISI-DLCMKLLSVD 250
G +++E P+++ K +D E K + N +C +LL+
Sbjct: 496 GCLLYEMIEGQ----APFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKS 551
Query: 251 VKQRLSI-------QDVINDSFF 266
+KQRL QDV+ FF
Sbjct: 552 IKQRLGCRNGRMGGQDVMAHPFF 574
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 71.6 bits (174), Expect = 1e-12
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 19/242 (7%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKE-VCVKEYELLKKLNHKCIIEALDCNKR 84
G C ++ ++ G A KK + E + + E ++L+K+N + ++ +
Sbjct: 198 GEVCACQV--RATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYET 255
Query: 85 KHTI----TFPYYSYTVLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLE 139
K + T ++ M E RA+++ +IC G+ LH IV+RDLK E
Sbjct: 256 KDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPE 315
Query: 140 NIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLG 199
NI++D+ +I+I D G AV V P + G G+ MAPEV + +Y +P D W+LG
Sbjct: 316 NILLDDH-GHIRISDLGLAVHV-PEGQTIKGRVGTVGYMAPEVVKNERYTFSP-DWWALG 372
Query: 200 IMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQ 253
+++E F K ++ ++ E Y++ + S LC +LL D +
Sbjct: 373 CLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARS--LCSQLLCKDPAE 430
Query: 254 RL 255
RL
Sbjct: 431 RL 432
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 71.6 bits (174), Expect = 1e-12
Identities = 54/187 (28%), Positives = 94/187 (49%), Gaps = 15/187 (8%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYL 100
++A+KK ++ H + + ++E ++L + H+ II D R TI Y V L
Sbjct: 50 RVAIKKISPFE-HQTYCQRTLREIKILLRFRHENIIGINDII-RAPTIEQMKDVYIVQDL 107
Query: 101 MKMSMLPTFEERAL-------WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKII 153
M+ + + + L + QI G+ Y+HS N++HRDLK N++++ + C++KI
Sbjct: 108 METDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-TTCDLKIC 166
Query: 154 DFGSAVDVGPNKEACHGIR---GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSN 210
DFG A P+ + + + APE+ K +D+WS+G ++ E SN
Sbjct: 167 DFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML--SN 224
Query: 211 KPAFPWK 217
+P FP K
Sbjct: 225 RPIFPGK 231
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 71.6 bits (174), Expect = 1e-12
Identities = 54/187 (28%), Positives = 94/187 (49%), Gaps = 15/187 (8%)
Query: 41 KLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYL 100
++A+KK ++ H + + ++E ++L + H+ II D R TI Y V L
Sbjct: 50 RVAIKKISPFE-HQTYCQRTLREIKILLRFRHENIIGINDII-RAPTIEQMKDVYIVQDL 107
Query: 101 MKMSMLPTFEERAL-------WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKII 153
M+ + + + L + QI G+ Y+HS N++HRDLK N++++ + C++KI
Sbjct: 108 METDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-TTCDLKIC 166
Query: 154 DFGSAVDVGPNKEACHGIR---GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSN 210
DFG A P+ + + + APE+ K +D+WS+G ++ E SN
Sbjct: 167 DFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML--SN 224
Query: 211 KPAFPWK 217
+P FP K
Sbjct: 225 RPIFPGK 231
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 71.6 bits (174), Expect = 1e-12
Identities = 55/158 (34%), Positives = 86/158 (53%), Gaps = 14/158 (8%)
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
+I + Y+HS IV+RDLK EN+M+ + +IK+ DFG A ++ ++ + I G+
Sbjct: 68 EIVCALEYIHSLGIVYRDLKPENLMLSKE-GHIKMADFGFAKEL---RDRTYTICGTPDY 123
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWK-IAKIDDVAFEAYTKNPTTL 236
+APE R + VD W+LGI+++E KP F K ++I D E K P +
Sbjct: 124 LAPESLARTGH-NKGVDWWALGILIYEMM--VGKPPFRGKTTSEIYDAIIEHKLKFPRSF 180
Query: 237 NISI-DLCMKLLSVDVKQRL-----SIQDVINDSFFQE 268
N++ DL KLL VD QR+ QDV + +F++
Sbjct: 181 NLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEK 218
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 71.6 bits (174), Expect = 1e-12
Identities = 55/158 (34%), Positives = 86/158 (53%), Gaps = 14/158 (8%)
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
+I + Y+HS IV+RDLK EN+M+ + +IK+ DFG A ++ ++ + I G+
Sbjct: 169 EIVCALEYIHSLGIVYRDLKPENLMLSKE-GHIKMADFGFAKEL---RDRTYTICGTPDY 224
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWK-IAKIDDVAFEAYTKNPTTL 236
+APE R + VD W+LGI+++E KP F K ++I D E K P +
Sbjct: 225 LAPESLARTGH-NKGVDWWALGILIYEMM--VGKPPFRGKTTSEIYDAIIEHKLKFPRSF 281
Query: 237 NISI-DLCMKLLSVDVKQRL-----SIQDVINDSFFQE 268
N++ DL KLL VD QR+ QDV + +F++
Sbjct: 282 NLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEK 319
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 71.6 bits (174), Expect = 1e-12
Identities = 72/290 (24%), Positives = 126/290 (42%), Gaps = 48/290 (16%)
Query: 26 GTTCEVEIVSKSDGSKLALKKF-RSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--N 82
G C V + +A+KK ++D H K ++E +LL+ L+H+ II D
Sbjct: 50 GIVCSV--LDTETNELVAMKKIANAFDNHMDAKRT-LREIKLLRHLDHENIIAIRDVVPP 106
Query: 83 KRKHTITFPYYSY----TVLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLK 137
+ + Y S T L+ + S EE +F Q+ G+ Y+HS NI+HRDLK
Sbjct: 107 PLRRQFSDVYISTELMDTDLHQIIRSNQSLSEEHCQYFLYQLLRGLKYIHSANIIHRDLK 166
Query: 138 LENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWS 197
N++++ + C++KI DFG A N + + APE+ +D+WS
Sbjct: 167 PSNLLLNAN-CDLKICDFGLARPTSENDFMTEYV-VTRWYRAPELLLNSSDYTAAIDVWS 224
Query: 198 LGIMMFEFFNNSNKPAFPWK--------------------------------IAKIDDVA 225
+G + E N KP FP K I ++ +
Sbjct: 225 VGCIFMELMN--RKPLFPGKDHVHQMRLLTELLGTPTESDLGFTHNEDAKRYIRQLPNFP 282
Query: 226 FEAYTKNPTTLN-ISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVD 274
+ K + +N ++IDL ++L+ D +R++++ +N + + H+ D
Sbjct: 283 RQPLAKLFSHVNPMAIDLVDRMLTFDPNRRITVEQALNHQYLAKLHDPND 332
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 71.6 bits (174), Expect = 1e-12
Identities = 64/268 (23%), Positives = 116/268 (42%), Gaps = 43/268 (16%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFP-- 91
+++ ++A+KK + + ++E +LL+ + H+ +I D + +F
Sbjct: 50 INRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHENVIALKDVMLPANRSSFKDV 109
Query: 92 YYSYTVL-----YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDES 146
Y Y ++ ++K S + + + Q+ G+ YLHS NI+HRDLK N++V+ +
Sbjct: 110 YLVYELMDTDLHQIIKSSQSLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNAN 169
Query: 147 LCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
C++KI DFG A N++ + APE+ GT +D+WS+G + E
Sbjct: 170 -CDLKICDFGLARTSQGNEQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEIL 228
Query: 207 NNSNKPAFPW--------------------KIAKIDDVAFEAYTKN-------------P 233
KP FP I ID+ + K+ P
Sbjct: 229 --GRKPIFPGTECLNQLKLIINVVGSQQESDIRFIDNPKARRFIKSLPYSRGTHLSNLYP 286
Query: 234 TTLNISIDLCMKLLSVDVKQRLSIQDVI 261
++IDL ++L D +R+S+ D +
Sbjct: 287 QANPLAIDLLQRMLVFDPTKRISVTDAL 314
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 71.6 bits (174), Expect = 1e-12
Identities = 64/259 (24%), Positives = 113/259 (42%), Gaps = 18/259 (6%)
Query: 25 QGTTCEVEIVSK-SDGSKLALKKF-RSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCN 82
+GT +V+ +G +A+K + L N +E +K + H +I +
Sbjct: 39 EGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNVIRMFEVM 98
Query: 83 KRKHTITFPYYSYTVLYLM-KMSMLPTF--EERALWFCQICEGIAYLHSHNIVHRDLKLE 139
K I F T L K+S +E +F Q+ + Y HS + HRDLK E
Sbjct: 99 ASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPE 158
Query: 140 NIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLG 199
N+++D + +K+ DFG + H G+ +APEV Y+G D+WS G
Sbjct: 159 NLLLDANGA-LKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 217
Query: 200 IMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQ 253
+++F F +SN + KI K + +T P + L ++L +
Sbjct: 218 VILFVLMAGYLPFEDSNLTSLYKKIFKAE------FTCPPWFSASAKKLIKRILDPNPAT 271
Query: 254 RLSIQDVINDSFFQENHNS 272
R++ +VI + +F++ + +
Sbjct: 272 RITFAEVIENEWFKKGYKA 290
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 71.6 bits (174), Expect = 1e-12
Identities = 64/272 (23%), Positives = 116/272 (42%), Gaps = 43/272 (15%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFP-- 91
V+ K+A+KK + + ++E +LL+ L H+ +I D H ++F
Sbjct: 50 VNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHENVIALKDVMMPIHKMSFKDV 109
Query: 92 YYSYTVL-----YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDES 146
Y Y ++ ++K S + + + + Q+ G+ Y+HS NI+HRDLK N++V+ +
Sbjct: 110 YLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNAN 169
Query: 147 LCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
C++KI DFG A + + APE+ GT +D+WS+G + E
Sbjct: 170 -CDLKICDFGLARASNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELL 228
Query: 207 NNSNKPAFPW--------------------KIAKIDDVAFEAYTKN-------------P 233
KP F + ID+ + Y ++ P
Sbjct: 229 --GRKPIFQGTECLNQLKLIVNILGSQREEDLEFIDNPKAKRYIRSLPYSPGMSLSRLYP 286
Query: 234 TTLNISIDLCMKLLSVDVKQRLSIQDVINDSF 265
++IDL K+L D +R+S+ + + +
Sbjct: 287 GAHVLAIDLLQKMLVFDPSKRISVSEALQHPY 318
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 71.6 bits (174), Expect = 1e-12
Identities = 48/172 (27%), Positives = 85/172 (48%), Gaps = 5/172 (2%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTI--TFPYY 93
+ G+ +A+K+F + +++ ++E LLK L H ++ L+ +RK + F +
Sbjct: 24 RETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFC 83
Query: 94 SYTVLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKI 152
TVL+ ++ E C Q G+AY H +HRD+K ENI++ + +K+
Sbjct: 84 ELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILL-TAQGQVKL 142
Query: 153 IDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
DFG A + P + + + APE+ GTPVD+W++G + E
Sbjct: 143 CDFGFARMLSPGENYTDYV-ATRWYRAPELLVGDTQYGTPVDVWAIGCLFAE 193
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 71.6 bits (174), Expect = 1e-12
Identities = 59/232 (25%), Positives = 106/232 (45%), Gaps = 31/232 (13%)
Query: 52 LHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEE 111
+ ++ KE +E + + LNH I++ + + I Y VL L K + +
Sbjct: 62 IKHNQKEKTAQEITIHRSLNHPNIVKFHNYFEDSQNI------YIVLELCKKRSMMELHK 115
Query: 112 RA---------LWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVG 162
R + QI +G+ YLH + I+HRDLKL N+ +++ L ++KI DFG A +
Sbjct: 116 RRKSITEFECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLND-LLHVKIGDFGLATRIE 174
Query: 163 PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKID 222
E + G+ +APE+ + K VD+WS+G +M+ +P F K K
Sbjct: 175 YEGERKKTLCGTPNYIAPEILTK-KGHSFEVDIWSIGCVMYTLL--VGQPPFETKTLKDT 231
Query: 223 -------DVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+ +Y + P + D+ + +L + + R +I ++N F +
Sbjct: 232 YSKIKKCEYRVPSYLRKP-----AADMVIAMLQPNPESRPAIGQLLNFEFLK 278
>YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 497
Score = 71.2 bits (173), Expect = 2e-12
Identities = 57/167 (34%), Positives = 80/167 (47%), Gaps = 29/167 (17%)
Query: 62 KEYELLKKLNHKCIIEALD--CNKRKHTITFP-------YYSYTVLYLMKMSMLPTFEER 112
KE +L +L+H II+ C++ H F +SY SM T E
Sbjct: 210 KEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSET--ES 267
Query: 113 ALWFCQICEGIAYLHSHNIVHRDLKLENIMV--DESLCNIKIIDFGSAVDVGPNKEACHG 170
L QI + + YLH +IVHRDLKL+NI++ E I + DFG A D+ NKE H
Sbjct: 268 LLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHT 327
Query: 171 IRGSEQLMAPEV-----------FQR---LKYEG--TPVDMWSLGIM 201
+ G+ + APEV F R L+ G + D+WSLG++
Sbjct: 328 VVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVI 374
>YKL116c [R] KOG0586 Serine/threonine protein kinase
Length = 518
Score = 71.2 bits (173), Expect = 2e-12
Identities = 50/185 (27%), Positives = 80/185 (43%), Gaps = 39/185 (21%)
Query: 62 KEYELLKKLNHKCIIEALDCNKR--------------KHTITFPYYSYTVLYLMKMSMLP 107
+E ++LK LNH CI++ L N K P + Y +L
Sbjct: 258 RELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLA 317
Query: 108 TFEER----ALW-----FCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNI-------- 150
R W F ++ + YLH ++I+HRDLKLENI++ S +I
Sbjct: 318 AVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPI 377
Query: 151 -------KIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
++ DFG + N E C GSE ++PE+ + Y+G D W+LG++++
Sbjct: 378 YCKQNFIELADFGLCKKI-ENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILY 436
Query: 204 EFFNN 208
F +
Sbjct: 437 SLFED 441
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 71.2 bits (173), Expect = 2e-12
Identities = 74/271 (27%), Positives = 110/271 (40%), Gaps = 52/271 (19%)
Query: 42 LALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLM 101
+ALKK R ++E LLK+L I+ D + + + L L
Sbjct: 37 VALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLK 96
Query: 102 K-MSMLPTFEERAL-----WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDF 155
+ M +P + + Q+C+GIAY HSH I+HRDLK +N+++++ N+K+ DF
Sbjct: 97 RYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKD-GNLKLGDF 155
Query: 156 GSAVDVG-PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSN---- 210
G A G P + H I + APEV K T VD WS+G + E N
Sbjct: 156 GLARAFGVPLRAYTHEI-VTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSG 214
Query: 211 -------------------------------KPAFP-WKIAKIDDVAFEAYTKNPTTLNI 238
KP+FP W+ + V P+
Sbjct: 215 DSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVV-------PSLDPR 267
Query: 239 SIDLCMKLLSVDVKQRLSIQDVINDSFFQEN 269
IDL KLL+ D R+S + +FQE+
Sbjct: 268 GIDLLDKLLAYDPINRISARRAAIHPYFQES 298
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 71.2 bits (173), Expect = 2e-12
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 16/170 (9%)
Query: 123 IAYLHSHNIVHRDLKLENIMV--DESLCNIKIIDFGSAVDVGPNK-----EACHGIRGSE 175
+ YLH + IVHRDLK EN++ + ++ I DFG + ++ AC G+
Sbjct: 142 VKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTAC----GTP 197
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKN-PT 234
+ MAPEVF+R Y G PVDMW++G++ + + A P ++ I+ + YT N P
Sbjct: 198 EYMAPEVFRRTGY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPC 256
Query: 235 TLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHAR 281
IS D K L D +RL+ D + F E + + + R
Sbjct: 257 WSGISETAKDFIKKCLENDPSKRLTAADALKHPFLSEKRPATSNLLPNVR 306
>SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase
Length = 471
Score = 71.2 bits (173), Expect = 2e-12
Identities = 36/90 (40%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
++ G+ YLH N +HRD+K NI++ S N+K+ DFG A + H G+
Sbjct: 112 EVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFW 171
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMFEFFN 207
MAPEV Q+ Y G D+WSLGI E N
Sbjct: 172 MAPEVIQQTSY-GLAADIWSLGITAIEMAN 200
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 71.2 bits (173), Expect = 2e-12
Identities = 58/177 (32%), Positives = 87/177 (48%), Gaps = 19/177 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G +A+KK + H + +E LLK +NHK II L+ + T+ Y V+
Sbjct: 49 GINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 99 YLMKMSMLPTF------EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKI 152
LM ++ E + Q+ GI +LHS I+HRDLK NI+V +S C +KI
Sbjct: 109 ELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKI 167
Query: 153 IDFGSAVDVGPNKEACHGIRGSEQLM-----APEVFQRLKYEGTPVDMWSLGIMMFE 204
+DFG A + AC + ++ APEV + Y+ VD+WS+G +M E
Sbjct: 168 LDFGLA------RTACTNFMMTPYVVTRYYRAPEVILGMGYKEN-VDIWSVGCIMAE 217
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 71.2 bits (173), Expect = 2e-12
Identities = 58/177 (32%), Positives = 87/177 (48%), Gaps = 19/177 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G +A+KK + H + +E LLK +NHK II L+ + T+ Y V+
Sbjct: 49 GINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 99 YLMKMSMLPTF------EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKI 152
LM ++ E + Q+ GI +LHS I+HRDLK NI+V +S C +KI
Sbjct: 109 ELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKI 167
Query: 153 IDFGSAVDVGPNKEACHGIRGSEQLM-----APEVFQRLKYEGTPVDMWSLGIMMFE 204
+DFG A + AC + ++ APEV + Y+ VD+WS+G +M E
Sbjct: 168 LDFGLA------RTACTNFMMTPYVVTRYYRAPEVILGMGYKEN-VDIWSVGCIMAE 217
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 71.2 bits (173), Expect = 2e-12
Identities = 66/276 (23%), Positives = 114/276 (40%), Gaps = 46/276 (16%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G ++A+KK H + +E LLK + H+ +I LD ++ Y V
Sbjct: 47 GLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 106
Query: 99 YLMKMSMLP-------TFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIK 151
+LM + T + QI G+ Y+HS +I+HRDLK N+ V+E C +K
Sbjct: 107 HLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELK 165
Query: 152 IIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNK 211
I+DFG A + G + APE+ + VD+WS+G +M E + +
Sbjct: 166 ILDFGLA---RHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELL--TGR 220
Query: 212 PAFPWK--------------------IAKIDDVAFEAYTKNPTTL-------------NI 238
FP + KI + Y ++ T + +
Sbjct: 221 TLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280
Query: 239 SIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVD 274
++DL K+L +D +R++ + ++F + H+ D
Sbjct: 281 AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDD 316
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 71.2 bits (173), Expect = 2e-12
Identities = 59/235 (25%), Positives = 107/235 (45%), Gaps = 23/235 (9%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHT--ITFPYY 93
+ D S + +K+ +DL + + + + E LL ++ H II D + + I Y
Sbjct: 191 REDSSLVIIKEINMYDLDSSQRRLALNEVSLLSRIEHPNIIAYYDSFEEEGVLMIEMEYA 250
Query: 94 SYTVLYLMKMSMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIK 151
L M +E + Q+C +AYLH ++++HRDLK N+ + +K
Sbjct: 251 DGGTLAQMLSRTQNLLDEEQIGDMMIQMCSAVAYLHENSVLHRDLKTANVFLTRD-SFVK 309
Query: 152 IIDFGSAVDVGPN--KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF---- 205
I DFG + +G + + G+ ++PE+ + Y DMW+LG +++E
Sbjct: 310 IGDFGISKIMGTETLAQGAKTVVGTPYYISPEMCSGVSY-NEKSDMWALGCILYEMCCLK 368
Query: 206 --FNNSNKPAFPWKIAKIDDVAFEAYT--KNPTTLNISIDLCMKLLSVDVKQRLS 256
F N PA ++ + AYT K P + + + + +LL +D ++R S
Sbjct: 369 KAFEGDNLPAL------VNSIMTCAYTPVKGPYSAEMKM-VIRELLQLDPQKRPS 416
>At5g55090 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 448
Score = 71.2 bits (173), Expect = 2e-12
Identities = 76/274 (27%), Positives = 122/274 (43%), Gaps = 39/274 (14%)
Query: 21 PRLIQGTTCEVEIVSKSDGSKLALK--KFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEA 78
P + +G+T V + + G A+K +F S +E +L KL+ I++
Sbjct: 10 PIIGRGSTATVSLGITNSGDFFAVKSAEFSS-------SAFLQREQSILSKLSSPYIVKY 62
Query: 79 LDCNKRK------HTITFPYYSYTVLY-LMKMS--MLPTFEERALWFCQICEGIAYLHSH 129
+ N K + + Y S L+ L+K S LP R+ + QI +G+ YLH
Sbjct: 63 IGSNVTKENDKLMYNLLMEYVSGGSLHDLIKNSGGKLPEPLIRS-YTRQILKGLMYLHDQ 121
Query: 130 NIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYE 189
IVH D+K +N+M+ + KI+D G A V N+ G+ M+PEV R + +
Sbjct: 122 GIVHCDVKSQNVMIGGEIA--KIVDLGCAKTVEENENL--EFSGTPAFMSPEV-ARGEEQ 176
Query: 190 GTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISI--------- 240
P D+W+LG + E S+ PW +++DV Y T + I
Sbjct: 177 SFPADVWALGCTVIEMATGSS----PW--PELNDVVAAIYKIGFTGESPVIPVWLSEKGQ 230
Query: 241 DLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVD 274
D K L D KQR ++++++ F E N D
Sbjct: 231 DFLRKCLRKDPKQRWTVEELLQHPFLDEEDNDSD 264
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 71.2 bits (173), Expect = 2e-12
Identities = 60/221 (27%), Positives = 101/221 (45%), Gaps = 14/221 (6%)
Query: 33 IVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY 92
++ KS+ K +KK R K ++E L+ KL I+E D K +
Sbjct: 32 VIHKSERRKYVVKKIRLAKQTERCKLAAIQEMSLISKLKSPYIVEYKDSWVEKDCVCI-V 90
Query: 93 YSY------TVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDES 146
SY T + + + E+ W Q+ I YLH++ ++HRDLK NI + +
Sbjct: 91 TSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAIDYLHNNRVLHRDLKCSNIFLTKE 150
Query: 147 LCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
+++ DFG A +G + + + G+ M PE+ + Y G D+WSLG MFE
Sbjct: 151 -NEVRLGDFGLAKLLGKD-DLASSMVGTPNYMCPELLADIPY-GYKSDIWSLGCCMFEV- 206
Query: 207 NNSNKPAF--PWKIAKIDDVAFEAYTKNPTTLNISIDLCMK 245
+++PAF P A I+ + + + P + S+ +K
Sbjct: 207 -AAHQPAFKAPDMAALINKINRSSLSPLPVMYSSSLKRLIK 246
>At1g54510 [R] KOG0589 Serine/threonine protein kinase
Length = 612
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/185 (30%), Positives = 87/185 (46%), Gaps = 11/185 (5%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSY 95
K + K LKK R + +E EL+ K+ H I+E D K Y
Sbjct: 24 KHEKKKYVLKKIRLARQTQRTRRSAHQEMELISKMRHPFIVEYKDSWVEKACYVCIVIGY 83
Query: 96 T----VLYLMKMSMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN 149
+ +K S F+E L W Q+ G+ YLHS++I+HRD+K NI + + +
Sbjct: 84 CEGGDMAQAIKKSNGVHFQEEKLCKWLVQLLMGLEYLHSNHILHRDVKCSNIFLTKEQ-D 142
Query: 150 IKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS 209
I++ DFG A + + + + G+ M PE+ + Y G+ D+WSLG ++E
Sbjct: 143 IRLGDFGLA-KILTSDDLTSSVVGTPSYMCPELLADIPY-GSKSDIWSLGCCIYEM--AY 198
Query: 210 NKPAF 214
KPAF
Sbjct: 199 LKPAF 203
>At1g10940 [T] KOG0583 Serine/threonine protein kinase
Length = 363
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/176 (31%), Positives = 87/176 (48%), Gaps = 26/176 (14%)
Query: 110 EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC-NIKIIDFG----SAVDVGPN 164
+E +F Q+ G++Y H+ I HRDLKLEN ++D S +KI DFG S + P
Sbjct: 98 DEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPK 157
Query: 165 KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMM-------FEFFNNSNKPAFPWK 217
G+ +APEV R +Y+G D+WS G+ + + F + + F
Sbjct: 158 STV-----GTPAYIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKT 212
Query: 218 IAKIDDVAFEAYTKNPTTLNISIDLCMKLLS----VDVKQRLSIQDVINDSFFQEN 269
I KI V + K P ++IS D C LLS + +R++I ++ S+F +N
Sbjct: 213 IQKIMAVQY----KIPDYVHISQD-CKNLLSRIFVANSLKRITIAEIKKHSWFLKN 263
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 70.9 bits (172), Expect = 2e-12
Identities = 64/246 (26%), Positives = 116/246 (47%), Gaps = 34/246 (13%)
Query: 26 GTTCEVEIVSKSDGSKLALKK-FRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--N 82
G C ++++ K + K L+K FR +E E+ LNH + ++ +
Sbjct: 127 GYICALKVMEKEEIIKYNLQKQFR-------------REVEIQTSLNHPNLTKSYGYFHD 173
Query: 83 KRKHTITFPYYSYTVLYLMKMSMLPTFEERAL-WFCQICEGIAYLHSHNIVHRDLKLENI 141
+++ + Y +Y + P + A + QI + Y+H NI+HRD+K ENI
Sbjct: 174 EKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENI 233
Query: 142 MVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIM 201
++ + IK+ DFG ++ + P + + G+ ++PE+ + +Y+ T +D W+LG++
Sbjct: 234 LIGFNNV-IKLTDFGWSI-INPPENRRKTVCGTIDYLSPEMVESREYDHT-IDAWALGVL 290
Query: 202 MFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQR 254
FE F K +IA +D K P+ ++ DL +KLL D K R
Sbjct: 291 AFELLTGAPPFEEEMKDTTYKRIAALD-------IKMPSNISQDAQDLILKLLKYDPKDR 343
Query: 255 LSIQDV 260
+ + DV
Sbjct: 344 MRLGDV 349
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 70.9 bits (172), Expect = 2e-12
Identities = 67/235 (28%), Positives = 109/235 (45%), Gaps = 18/235 (7%)
Query: 41 KLALKKFRSWDLHN-HHKEVCV-KEYELLKKLNHKCIIEALDC--NKRKHTITFPYY--S 94
++A+K + + N + KEV + +E LK L+H I++ + N R I Y
Sbjct: 76 QVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGG 135
Query: 95 YTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIID 154
Y+ K L L F Q+ G+ Y+HS +VHRDLKLEN+++D++ N+ I D
Sbjct: 136 EFYKYIQKKRRLKEMNACRL-FSQLISGVHYIHSKGLVHRDLKLENLLLDKNE-NLVITD 193
Query: 155 FGSAVDVGPNKEACHGIRGSEQLMAPE-VFQRLKYEGTPVDMWSLGIMMFEFF------- 206
FG + E GS APE V YE D+WS G++++
Sbjct: 194 FGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWD 253
Query: 207 NNSNKPAFPWKIAKIDDVAFEAYTKNPT-TLNISIDLCMKLLSVDVKQRLSIQDV 260
++ N P I ++ + K P L I DL ++L D K+R++++ +
Sbjct: 254 DDPNNPEGS-DIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQI 307
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 70.9 bits (172), Expect = 2e-12
Identities = 51/161 (31%), Positives = 82/161 (50%), Gaps = 15/161 (9%)
Query: 111 ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA--VDVGPNKEAC 168
E L F Q+ I +LH IVHRD+K EN++VD S +K+IDFGSA + GP
Sbjct: 951 EAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVD-SHGFVKLIDFGSAAYIKSGP----F 1005
Query: 169 HGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDV--AF 226
G+ APEV Y+G P D+W+LG++++ N P + ID++
Sbjct: 1006 DVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKEN-PYY-----NIDEILEGE 1059
Query: 227 EAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+ K+ I L ++L+ +V +R +I ++ D + +
Sbjct: 1060 LRFDKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWLK 1100
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/177 (32%), Positives = 87/177 (48%), Gaps = 19/177 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G +A+KK + H + +E LLK +NHK II L+ + T+ Y V+
Sbjct: 49 GINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 99 YLMKMSMLPTF------EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKI 152
LM ++ E + Q+ GI +LHS I+HRDLK NI+V +S C +KI
Sbjct: 109 ELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKI 167
Query: 153 IDFGSAVDVGPNKEACHGIRGSEQLM-----APEVFQRLKYEGTPVDMWSLGIMMFE 204
+DFG A + AC + ++ APEV + Y+ VD+WS+G +M E
Sbjct: 168 LDFGLA------RTACTNFMMTPYVVTRYYRAPEVILGMGYKEN-VDIWSVGCIMGE 217
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/175 (33%), Positives = 89/175 (50%), Gaps = 32/175 (18%)
Query: 110 EERALWF-CQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFG----SAVDVGPN 164
E+R ++ +I + YLHS IV+RDLKLEN+M+D+ +IKI DFG D
Sbjct: 245 EDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKD-GHIKITDFGLCKEGITDAATM 303
Query: 165 KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE-------FFNNSNKPAFPWK 217
K C G+ + +APEV + Y G VD W LG++M+E F+N ++ F +
Sbjct: 304 KTFC----GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLF--E 356
Query: 218 IAKIDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRL-----SIQDVINDSFF 266
+ ++D+ F P TL+ L LL D +RL ++++ SFF
Sbjct: 357 LILMEDIKF------PRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFF 405
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/177 (32%), Positives = 87/177 (48%), Gaps = 19/177 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G +A+KK + H + +E LLK +NHK II L+ + T+ Y V+
Sbjct: 49 GINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 99 YLMKMSMLPTF------EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKI 152
LM ++ E + Q+ GI +LHS I+HRDLK NI+V +S C +KI
Sbjct: 109 ELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKI 167
Query: 153 IDFGSAVDVGPNKEACHGIRGSEQLM-----APEVFQRLKYEGTPVDMWSLGIMMFE 204
+DFG A + AC + ++ APEV + Y+ VD+WS+G +M E
Sbjct: 168 LDFGLA------RTACTNFMMTPYVVTRYYRAPEVILGMGYKEN-VDIWSVGCIMGE 217
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/177 (32%), Positives = 87/177 (48%), Gaps = 19/177 (10%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL 98
G +A+KK + H + +E LLK +NHK II L+ + T+ Y V+
Sbjct: 49 GINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 99 YLMKMSMLPTF------EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKI 152
LM ++ E + Q+ GI +LHS I+HRDLK NI+V +S C +KI
Sbjct: 109 ELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV-KSDCTLKI 167
Query: 153 IDFGSAVDVGPNKEACHGIRGSEQLM-----APEVFQRLKYEGTPVDMWSLGIMMFE 204
+DFG A + AC + ++ APEV + Y+ VD+WS+G +M E
Sbjct: 168 LDFGLA------RTACTNFMMTPYVVTRYYRAPEVILGMGYKEN-VDIWSVGCIMGE 217
>CE20717 [T] KOG0583 Serine/threonine protein kinase
Length = 301
Score = 70.9 bits (172), Expect = 2e-12
Identities = 47/147 (31%), Positives = 73/147 (48%), Gaps = 7/147 (4%)
Query: 62 KEYELLKKLNHKCIIEALDCNK---RKHTITFPYYSYTVL--YLMKMSMLPTFEERALWF 116
+E E+ K+ H I L + K I YY L ++++ L A F
Sbjct: 71 RELEITMKVRHPHIARCLAITRPAPTKFVIISDYYERGTLLEWILQKKRLKEHPLAATLF 130
Query: 117 CQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQ 176
Q+ E I YLH IVHRD+KLENI++D + +IK+IDFG A + +E G++
Sbjct: 131 RQLIEAINYLHKRGIVHRDVKLENILIDGN-GDIKLIDFGFARHI-ERRERSRSFCGTQP 188
Query: 177 LMAPEVFQRLKYEGTPVDMWSLGIMMF 203
P++ + YE D ++ GI++F
Sbjct: 189 YTCPQITKYRPYEAYAADYYACGIVLF 215
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 70.9 bits (172), Expect = 2e-12
Identities = 72/296 (24%), Positives = 128/296 (42%), Gaps = 62/296 (20%)
Query: 17 GNDSPRLIQGTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCII 76
G S +++GT V I KLA + F+S H + +E LLK ++H+ +I
Sbjct: 37 GQVSKAVVRGTNMHVAI------KKLA-RPFQS----AVHAKRTYRELRLLKHMDHENVI 85
Query: 77 EALDC---NKRKHTITFPYYSYTVLYLM--------KMSMLPTFEERALWFCQICEGIAY 125
LD + ++ Y V +LM +M L + L + QI G+ Y
Sbjct: 86 GLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVY-QILRGLKY 144
Query: 126 LHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQR 185
+HS ++HRDLK NI V+E C ++I+DFG A P + G + APE+
Sbjct: 145 IHSAGVIHRDLKPSNIAVNED-CELRILDFGLA---RPTENEMTGYVATRWYRAPEIMLN 200
Query: 186 LKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWK--------------------IAKIDDVA 225
+ VD+WS+G +M E + + FP + KI +
Sbjct: 201 WMHYDQTVDIWSVGCIMAELI--TRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSES 258
Query: 226 FEAYTKNPTTLN-------------ISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
+Y ++ + ++IDL K+L +D ++R++ ++ ++ + ++
Sbjct: 259 ARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEK 314
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 70.5 bits (171), Expect = 3e-12
Identities = 62/229 (27%), Positives = 105/229 (45%), Gaps = 34/229 (14%)
Query: 62 KEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERAL------- 114
+E ++ + + H I + LD + +++ YY L M +E++ L
Sbjct: 110 REGQIQQMIRHPNITQLLDILETENS----YYLVMELCPGGNLMHKIYEKKRLEESEARR 165
Query: 115 WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVG------PNKEAC 168
+ Q+ + +LH +VHRDLK+EN+++DE NIK+IDFG + G P C
Sbjct: 166 YIRQLISAVEHLHRAGVVHRDLKIENLLLDED-NNIKLIDFGLSNCAGILGYSDPFSTQC 224
Query: 169 HGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKI------AKID 222
GS APE+ R KY G +D+WS+G+ M+ + P+ + A
Sbjct: 225 ----GSPAYAAPELLARKKY-GPKIDVWSIGVNMYAMLTGT----LPFTVEPFSLRALYQ 275
Query: 223 DVAFEAYTKNPTTLNI-SIDLCMKLLSVDVKQRLSIQDVINDSFFQENH 270
+ + PT L+ +I LL D +R +IQ + + + EN+
Sbjct: 276 KMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENY 324
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 70.5 bits (171), Expect = 3e-12
Identities = 76/286 (26%), Positives = 125/286 (43%), Gaps = 48/286 (16%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLN---HKCIIEALDC-------NKRK 85
K+ G +ALK+ R ++E +L+ L H ++ D + K
Sbjct: 34 KNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETK 93
Query: 86 HTITFPYYSYTVL-YLMKMSM--LPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIM 142
T+ F + + YL K+ +PT + + F Q+ G+ +LHSH +VHRDLK +NI+
Sbjct: 94 LTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMF-QLLRGLDFLHSHRVVHRDLKPQNIL 152
Query: 143 VDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMM 202
V S IK+ DFG A + + A + + APEV + Y TPVD+WS+G +
Sbjct: 153 VTSS-GQIKLADFGLA-RIYSFQMALTSVVVTLWYRAPEVLLQSSY-ATPVDLWSVGCIF 209
Query: 203 FEFFNNSNKPAFPW-----KIAKIDDV------------------AFEAYTKNPTTL--- 236
E F KP F ++ KI DV AF + + P
Sbjct: 210 AEMFR--RKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVT 267
Query: 237 ---NISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAH 279
+ DL +K L+ + +R+S ++ +FQ+ + + +H
Sbjct: 268 DIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSH 313
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 70.5 bits (171), Expect = 3e-12
Identities = 56/170 (32%), Positives = 87/170 (50%), Gaps = 9/170 (5%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF--PYYSYT 96
G KLA K ++ + + KE E ++ +L+H +I+ D + K+ I Y
Sbjct: 197 GLKLAAKIIKTRGMKD--KEEVKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGG 254
Query: 97 VLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESLCNIKII 153
L+ ++ S T + L+ QICEGI ++H I+H DLK ENI+ V+ IKII
Sbjct: 255 ELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKII 314
Query: 154 DFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
DFG A P +E G+ + +APEV + P DMWS+G++ +
Sbjct: 315 DFGLARRYKP-REKLKVNFGTPEFLAPEVV-NYDFVSFPTDMWSVGVIAY 362
>Hs14042966 [T] KOG0583 Serine/threonine protein kinase
Length = 273
Score = 70.5 bits (171), Expect = 3e-12
Identities = 38/146 (26%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Query: 62 KEYELLKKLNHKCIIEALD----CNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFC 117
+E +L+ + H I+ + CN + + + + + + + +P + R L F
Sbjct: 59 RELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDL-FA 117
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQL 177
QI + YLH H++VHRDLK EN+++ +K+ DFG + GS
Sbjct: 118 QIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAY 177
Query: 178 MAPEVFQRLKYEGTPVDMWSLGIMMF 203
+PEV + Y+ D+WS+G++++
Sbjct: 178 ASPEVLLGIPYDPKKYDVWSMGVVLY 203
>CE27177 [T] KOG4279 Serine/threonine protein kinase
Length = 1378
Score = 70.5 bits (171), Expect = 3e-12
Identities = 63/245 (25%), Positives = 104/245 (41%), Gaps = 29/245 (11%)
Query: 61 VKEYELLKKLNHKCIIEALDCN------KRKHTITFPYY--SYTVLYLMKMSMLPTFEER 112
++E L L H I++ L C+ H + F + ++ L++ P E
Sbjct: 707 MEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENA 766
Query: 113 ALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGI 171
++ QI EG+ YLH IVHRD+K +N++V+ KI DFG+ +
Sbjct: 767 MNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETF 826
Query: 172 RGSEQLMAPEVFQR-LKYEGTPVDMWSLGIMMFE-------FFNNSNKPAFPWKIAKIDD 223
G+ Q MAPEV + G P D+WS G M E F N A +++
Sbjct: 827 TGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVG---- 882
Query: 224 VAFEAYTKNPTTLNISIDLCMKLLS----VDVKQRLSIQDVINDSFFQENHNSVDGVSAH 279
F+ + PT + + C + + R S +D++ D F NH+S+ +
Sbjct: 883 -MFKTHPPIPTEIT---EKCRNFIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSG 938
Query: 280 ARTKR 284
+ K+
Sbjct: 939 SINKK 943
>At4g08500 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 70.5 bits (171), Expect = 3e-12
Identities = 68/252 (26%), Positives = 116/252 (45%), Gaps = 27/252 (10%)
Query: 38 DGSKLALKKFRSWDLHNHHKEVCVKEYE----LLKKLNHKCIIEALDCNKRKHTITFPYY 93
DG A+K+ D + +E C+++ E LL +L H+ I+ K +
Sbjct: 354 DGDFFAVKEVSLLDQGSQAQE-CIQQLEGEIKLLSQLQHQNIVRYRGTAKDGSNL----- 407
Query: 94 SYTVLYLMKMSMLPTFEER--------ALWFCQICEGIAYLHSHNIVHRDLKLENIMVDE 145
Y L L+ L +R +L+ QI +G+ YLH +HRD+K NI+VD
Sbjct: 408 -YIFLELVTQGSLLKLYQRYQLRDSVVSLYTRQILDGLKYLHDKGFIHRDIKCANILVDA 466
Query: 146 SLCNIKIIDFGSA-VDVGPNKEACHGIRGSEQLMAPEVFQRLKYE--GTPVDMWSLGIMM 202
+ +K+ DFG A V + ++C +G+ MAPEV R + G+P D+WSLG +
Sbjct: 467 NGA-VKLADFGLAKVSKFNDIKSC---KGTPFWMAPEVINRKDSDGYGSPADIWSLGCTV 522
Query: 203 FEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDL-CMKLLSVDVKQRLSIQDVI 261
E + + + + + P TL++ L +K L V+ ++R + +++
Sbjct: 523 LEMCTGQIPYSDLEPVQALFRIGRGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELL 582
Query: 262 NDSFFQENHNSV 273
N F + SV
Sbjct: 583 NHPFVRRPLPSV 594
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 70.5 bits (171), Expect = 3e-12
Identities = 66/243 (27%), Positives = 112/243 (45%), Gaps = 23/243 (9%)
Query: 25 QGTTCEVEIVSKSDGSKLALKKFRSWD--LHNHHKEVCVKEYELLKKLNHKCIIEALDCN 82
+G +V V K + S++ K D + +H E E ++L K++H I++
Sbjct: 142 KGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQL---- 197
Query: 83 KRKHTITFPYYSYTVLYLMKMSML-------PTFEE--RALWFCQICEGIAYLHSHNIVH 133
K++ Y Y VL + L F E ++ +I +++LH I+H
Sbjct: 198 --KYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMH 255
Query: 134 RDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPV 193
RDLK ENI++D ++ + DFG A + N + + + G+ + MAPE+ R K
Sbjct: 256 RDLKPENILMDTD-GHVMLTDFGLAKEFEENTRS-NSMCGTTEYMAPEIV-RGKGHDKAA 312
Query: 194 DMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMK-LLSVDVK 252
D WS+GI+++E + KP F KI + K P L+ +K LL + +
Sbjct: 313 DWWSVGILLYEML--TGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPE 370
Query: 253 QRL 255
+RL
Sbjct: 371 RRL 373
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 70.5 bits (171), Expect = 3e-12
Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 46/276 (16%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKL-NHKCIIEALDC----NKRKHTITF 90
K+ G +ALKK R + ++E +L+ L I+ +D NK T+ +
Sbjct: 36 KATGMIVALKKTRLHEDEEGVPPTTLREISILRMLARDPHIVRLMDVKQGINKEGKTVLY 95
Query: 91 PYYSYTVLYLMKM--------SMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIM 142
+ Y L K +P + L + Q+C+G+A+ H H ++HRDLK N++
Sbjct: 96 LVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMY-QLCKGMAFCHGHGVLHRDLKPHNLL 154
Query: 143 VDESLCNIKIIDFGSA-VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLG-- 199
+D +KI D G A P K+ H I + APEV + T VDMWS+G
Sbjct: 155 MDRKTMTLKIADLGLARAFTLPMKKYTHEIL-TLWYRAPEVLLGATHYSTGVDMWSVGCI 213
Query: 200 --------------------IMMFEFFNNSNKPAFPWKIAKIDD-------VAFEAYTKN 232
+ +F N+ +P ++K+ D T
Sbjct: 214 FAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVWP-GVSKLKDWHEYPQWKPLSLSTAV 272
Query: 233 PTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQE 268
P +DL K+L + +R+S + + +F +
Sbjct: 273 PNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYFDD 308
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 70.5 bits (171), Expect = 3e-12
Identities = 71/276 (25%), Positives = 119/276 (42%), Gaps = 38/276 (13%)
Query: 35 SKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPY 92
S S G +ALKK R ++E LLK L H +++ D + + F Y
Sbjct: 27 SNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEY 86
Query: 93 YSYTVLYLM-KMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIK 151
+ + LM K + T + + QI + + + H++ I+HRDLK +N++VD + IK
Sbjct: 87 LNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVD-TAGKIK 145
Query: 152 IIDFGSAVDVG-PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSN 210
+ DFG A P + H + + APE+ K+ T VD+WSLG + E
Sbjct: 146 LADFGLARAFNVPMRAYTHEV-VTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMI--MR 202
Query: 211 KPAFPW------------KIAKIDDVAFEAYTK-----------------NPTTLNISID 241
+ FP ++ D+ + T+ P T + + +
Sbjct: 203 RSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAHE 262
Query: 242 LCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVS 277
L M +L D R+S +D + ++F+ N VD V+
Sbjct: 263 LIMSMLCYDPNLRISAKDALQHAYFR-NVQHVDHVA 297
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 70.5 bits (171), Expect = 3e-12
Identities = 56/185 (30%), Positives = 83/185 (44%), Gaps = 21/185 (11%)
Query: 111 ERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVG-PNKEACH 169
E +F Q+ G+ YLH I HRDLK EN+++DE N+KI DFG A KE
Sbjct: 121 EAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEH-DNVKISDFGMATMFRCKGKERLL 179
Query: 170 GIR-GSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEA 228
R G+ +APEV Q+ Y P D+WS G+++ PW + F
Sbjct: 180 DKRCGTLPYVAPEVLQK-AYHAQPADLWSCGVILVTMLAGE----LPWDQPSTNCTEFTN 234
Query: 229 YTKN---------PTTLNISIDLCMKLLSVDVKQRLSIQDVINDSF----FQENHNSVDG 275
+ N ++I L KLL+ RL+++ ++ + F +N S D
Sbjct: 235 WRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDHKWCNMQFADNERSYDL 294
Query: 276 VSAHA 280
V + A
Sbjct: 295 VDSAA 299
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 70.1 bits (170), Expect = 4e-12
Identities = 64/245 (26%), Positives = 111/245 (45%), Gaps = 16/245 (6%)
Query: 25 QGTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEV--CVKEYELLKKLNHKCIIE---AL 79
+G+ +V IV K D K+ K+ + EV +E ++++ L H ++ +
Sbjct: 31 KGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSF 90
Query: 80 DCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLE 139
+ + + Y ++ ++ T L+ C++ + YL ++I+HRD+K +
Sbjct: 91 QDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPD 150
Query: 140 NIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGT----PVDM 195
NI++DE ++ I DF A V E + G++ MAPEVFQ G PVD
Sbjct: 151 NILLDEH-GHVHITDFNIAT-VVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDW 208
Query: 196 WSLGIMMFEFFNNSNKPAFPWKIAKIDDV----AFEAYTKNPTTLNISIDLCMKLLSVDV 251
WSLGI +E +P + ID++ E + T + L KLL+ D
Sbjct: 209 WSLGITAYELLRGW-RPYEIHSVTPIDEILNMFKVERVHYSSTWCKGMVALLRKLLTKDP 267
Query: 252 KQRLS 256
+ R+S
Sbjct: 268 ESRVS 272
>Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 626
Score = 70.1 bits (170), Expect = 4e-12
Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 26/247 (10%)
Query: 39 GSKLALKKFR-SWDLHNHHKEVCVKEYE--LLKKLNHKCIIEALDC--NKRKHTITFPYY 93
G +LA K+ + D KEV E E LLK L H+ I++ C ++ + T+T +
Sbjct: 385 GRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTI-FM 443
Query: 94 SY----TVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN 149
Y +V +K T + QI EG++YLHS+ IVHRD+K NI+ D S N
Sbjct: 444 EYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRD-SAGN 502
Query: 150 IKIIDFGSA---VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFF 206
+K+ DFG++ + + + G+ M+PEV Y G D+WSLG + E
Sbjct: 503 VKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGY-GRKADVWSLGCTVVEML 561
Query: 207 NNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLC------MKLLSVDVKQRLSIQDV 260
+ KP PW + F+ T+ PT + + ++ + V+ +QR S +++
Sbjct: 562 --TEKP--PWAEYEAMAAIFKIATQ-PTNPQLPSHISEHGRDFLRRIFVEARQRPSAEEL 616
Query: 261 INDSFFQ 267
+ F Q
Sbjct: 617 LTHHFAQ 623
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 70.1 bits (170), Expect = 4e-12
Identities = 47/148 (31%), Positives = 81/148 (53%), Gaps = 6/148 (4%)
Query: 61 VKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLMK-MSMLPTFEERALWFC 117
++E +LL++L+H II LD +K ++ F + + ++K S++ T +
Sbjct: 60 LREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYML 119
Query: 118 QICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVG-PNKEACHGIRGSEQ 176
+G+ YLH H I+HRDLK N+++DE+ +K+ DFG A G PN+ H + +
Sbjct: 120 MTLQGLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQV-VTRW 177
Query: 177 LMAPEVFQRLKYEGTPVDMWSLGIMMFE 204
APE+ + G VDMW++G ++ E
Sbjct: 178 YRAPELLFGARMYGVGVDMWAVGCILAE 205
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 70.1 bits (170), Expect = 4e-12
Identities = 51/192 (26%), Positives = 93/192 (47%), Gaps = 9/192 (4%)
Query: 25 QGTTCEVEIVSK----SDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIE--- 77
QG+ +V +V K G A+K + L + E ++L +NH +++
Sbjct: 70 QGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHY 129
Query: 78 ALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLK 137
A + + I + + ++ T E+ + ++ G+ +LHS I++RDLK
Sbjct: 130 AFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLK 189
Query: 138 LENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWS 197
ENI++DE +IK+ DFG + + +++ + G+ + MAPEV R + + D WS
Sbjct: 190 PENILLDEE-GHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS-ADWWS 247
Query: 198 LGIMMFEFFNNS 209
G++MFE S
Sbjct: 248 YGVLMFEMLTGS 259
Score = 59.3 bits (142), Expect = 6e-09
Identities = 55/166 (33%), Positives = 79/166 (47%), Gaps = 15/166 (9%)
Query: 109 FEERALWFC--QICEGIAYLHSHNIVHRDLKLENIM-VDES---LCNIKIIDFGSAVDVG 162
F ER F I + + YLHS +VHRDLK NI+ VDES C ++I DFG A +
Sbjct: 507 FSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPEC-LRICDFGFAKQLR 565
Query: 163 PNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPW 216
+ +APEV +R Y+ D+WSLGI+++ F N
Sbjct: 566 AENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIWSLGILLYTMLAGYTPFANGPSDTPEE 624
Query: 217 KIAKIDDVAFEAYTKNPTTLN-ISIDLCMKLLSVDVKQRLSIQDVI 261
+ +I F N T++ + DL K+L VD QRL+ + V+
Sbjct: 625 ILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVL 670
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 70.1 bits (170), Expect = 4e-12
Identities = 64/242 (26%), Positives = 113/242 (46%), Gaps = 20/242 (8%)
Query: 57 KEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLMKMSMLPTFEERAL 114
+E +E +L+++ H +I D N+ + S L+ EE A
Sbjct: 68 REEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEAT 127
Query: 115 WFC-QICEGIAYLHSHNIVHRDLKLENIMVDES---LCNIKIIDFGSAVDVGPNKEACHG 170
F QI +G+ YLH+ I H DLK ENIM+ + + +IK+IDFG A ++ E
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVE-FKN 186
Query: 171 IRGSEQLMAPEVFQRLKYE--GTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVAFEA 228
I G+ + +APE+ + YE G DMWS+G++ + + ++ K + ++ +
Sbjct: 187 IFGTPEFVAPEI---VNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVS 243
Query: 229 YTKN----PTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVDGVSAHARTKR 284
Y + T ++ D KLL + ++RL+IQ+ + + VD A R +
Sbjct: 244 YDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWI----TPVDNQQAMVRRES 299
Query: 285 IL 286
++
Sbjct: 300 VV 301
>CE18366 [T] KOG0583 Serine/threonine protein kinase
Length = 331
Score = 70.1 bits (170), Expect = 4e-12
Identities = 50/156 (32%), Positives = 77/156 (49%), Gaps = 17/156 (10%)
Query: 57 KEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVL-------YLMKMSMLPTF 109
K+ +E E++K L H + + I+FP + V L KM + T
Sbjct: 80 KKFLPREKEIVKLLKHDNVCRLYEM------ISFPDHIIFVTEFCAGGDLLRKMKKIKTM 133
Query: 110 EER--ALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEA 167
E F Q + +L S+NIVHRDLK ENI +D+ N+K+ DFG + + P E
Sbjct: 134 SEENAKFTFRQFIAALMHLQSYNIVHRDLKCENIFLDK-YENVKLGDFGFSRILKPG-EK 191
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF 203
GS +APE+ + +Y G VD+WS G++++
Sbjct: 192 SGTFCGSRAYVAPEILRGREYSGNAVDVWSTGVILY 227
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 70.1 bits (170), Expect = 4e-12
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 45/235 (19%)
Query: 53 HNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLM------KMS 104
H KE KE + + L H ++ D + + + + + S L+ KMS
Sbjct: 6298 HESDKETVRKEIQTMSVLRHPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMS 6357
Query: 105 MLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN-IKIIDFGSAVDVGP 163
+E + Q+C+G+ ++H +N VH DLK ENIM N +K+IDFG + P
Sbjct: 6358 E----DEAVEYMRQVCKGLCHMHENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDP 6413
Query: 164 NKEACHGIRGSEQLMAPEVFQRLKYEGTPV----DMWSLGIMMFEFFNN----------- 208
K++ G+ + APEV EG PV DMWS+G++ + +
Sbjct: 6414 -KQSVKVTTGTAEFAAPEV-----AEGKPVGYYTDMWSVGVLSYILLSGLSPFGGENDDE 6467
Query: 209 --SNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVI 261
N + W +DD AF +++ D KLL D R++I +
Sbjct: 6468 TLRNVKSCDW---NMDDSAFSGISED------GKDFIRKLLLADPNTRMTIHQAL 6513
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 70.1 bits (170), Expect = 4e-12
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 45/235 (19%)
Query: 53 HNHHKEVCVKEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLM------KMS 104
H KE KE + + L H ++ D + + + + + S L+ KMS
Sbjct: 5969 HESDKETVRKEIQTMSVLRHPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMS 6028
Query: 105 MLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN-IKIIDFGSAVDVGP 163
+E + Q+C+G+ ++H +N VH DLK ENIM N +K+IDFG + P
Sbjct: 6029 E----DEAVEYMRQVCKGLCHMHENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDP 6084
Query: 164 NKEACHGIRGSEQLMAPEVFQRLKYEGTPV----DMWSLGIMMFEFFNN----------- 208
K++ G+ + APEV EG PV DMWS+G++ + +
Sbjct: 6085 -KQSVKVTTGTAEFAAPEV-----AEGKPVGYYTDMWSVGVLSYILLSGLSPFGGENDDE 6138
Query: 209 --SNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVI 261
N + W +DD AF +++ D KLL D R++I +
Sbjct: 6139 TLRNVKSCDW---NMDDSAFSGISED------GKDFIRKLLLADPNTRMTIHQAL 6184
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 70.1 bits (170), Expect = 4e-12
Identities = 50/174 (28%), Positives = 86/174 (48%), Gaps = 13/174 (7%)
Query: 45 KKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY-YSYTVLYLMKM 103
KK+ SW+ + V ++E + L ++NH I++ + + + F + Y LY +
Sbjct: 45 KKYFSWE-----ECVNLREVKSLSRMNHPNIVKLKEVIRENDILYFVFEYMECNLYQLMK 99
Query: 104 SMLPTFEERAL--WFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDV 161
F E + W Q+ +G++Y+H HRDLK EN++V + + IKI D G A ++
Sbjct: 100 DRPKHFAESDIRNWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKDV--IKIADLGLAREI 157
Query: 162 GPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFP 215
+ + + APEV + + VDMW++G +M E S +P FP
Sbjct: 158 DSSPPYTEYV-STRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELL--SLRPLFP 208
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 70.1 bits (170), Expect = 4e-12
Identities = 46/167 (27%), Positives = 81/167 (47%), Gaps = 8/167 (4%)
Query: 110 EERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLC-NIKIIDFGSAVDVGPNKEAC 168
+E +F Q+ G++Y H+ I HRDLKLEN ++D S +KI DFG + + +
Sbjct: 117 DEARFFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPK 176
Query: 169 HGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNS---NKPAFPWKIAKIDDVA 225
+ G+ +APE+ R +Y+G D+WS G+ ++ + P P K
Sbjct: 177 STV-GTPAYIAPEILLRQEYDGKLADVWSCGVTLYVMLVGAYPFEDPQEPRDYRKTIQRI 235
Query: 226 FEAYTKNPTTLNISID---LCMKLLSVDVKQRLSIQDVINDSFFQEN 269
P L++S + L ++ D R++I ++ +D +F +N
Sbjct: 236 LSVTYSIPEDLHLSPECRHLISRIFVADPATRITIPEITSDKWFLKN 282
>At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 348
Score = 70.1 bits (170), Expect = 4e-12
Identities = 51/178 (28%), Positives = 88/178 (48%), Gaps = 21/178 (11%)
Query: 57 KEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYYSYTVLYLMKMSMLPTF-----EE 111
+++C +E E+L+ ++H +++ D I +L M L +E
Sbjct: 111 RQIC-REIEILRSVDHPNVVKCHDMFDHNGEIQ------VLLEFMDQGSLEGAHIWQEQE 163
Query: 112 RALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGI 171
A QI G+AYLH +IVHRD+K N++++ S N+KI DFG + + + C+
Sbjct: 164 LADLSRQILSGLAYLHRRHIVHRDIKPSNLLIN-SAKNVKIADFGVSRILAQTMDPCNSS 222
Query: 172 RGSEQLMAPE----VFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWKIAKIDDVA 225
G+ M+PE +Y+G D+WSLG+ + EF+ FP+ +++ D A
Sbjct: 223 VGTIAYMSPERINTDLNHGRYDGYAGDVWSLGVSILEFYLG----RFPFAVSRQGDWA 276
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 70.1 bits (170), Expect = 4e-12
Identities = 54/187 (28%), Positives = 87/187 (45%), Gaps = 16/187 (8%)
Query: 36 KSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKL-NHKCIIEALDC----NKRKHTITF 90
K+ G +ALKK R + ++E +L+ L ++ +D +K T+ +
Sbjct: 34 KATGKIVALKKTRLHEDEEGVPSTTLREISILRMLARDPHVVRLMDVKQGLSKEGKTVLY 93
Query: 91 PYYSYTVLYLMKM--------SMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIM 142
+ Y + K +PT ++L + Q+C+G+A+ H H I+HRDLK N++
Sbjct: 94 LVFEYMDTDVKKFIRSFRSTGKNIPTQTIKSLMY-QLCKGMAFCHGHGILHRDLKPHNLL 152
Query: 143 VDESLCNIKIIDFGSA-VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIM 201
+D +KI D G A P K+ H I + APEV + T VDMWS+G +
Sbjct: 153 MDPKTMRLKIADLGLARAFTLPMKKYTHEIL-TLWYRAPEVLLGATHYSTAVDMWSVGCI 211
Query: 202 MFEFFNN 208
E N
Sbjct: 212 FAELVTN 218
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 70.1 bits (170), Expect = 4e-12
Identities = 59/226 (26%), Positives = 113/226 (49%), Gaps = 29/226 (12%)
Query: 62 KEYELLKKLNHKCIIEALDC--NKRKHTITFPYYSYTVLYLMKM------SMLPTFEERA 113
+E LLK+L H+ ++E +D N+ K + + Y V L +M +P F+
Sbjct: 193 REIALLKQLKHRHVVELVDVLYNEEKQKM-YLVMEYCVGGLQEMIDYQPDKRMPLFQAHG 251
Query: 114 LWFCQICEGIAYLHSHNIVHRDLKLENIM--VDESLCNIKIIDFGSA--VDVGPNKEACH 169
+F Q+ +G+ YLHS ++H+D+K N++ +D++L KI DFG A +D+ + C
Sbjct: 252 -YFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTL---KISDFGVAEQLDLFAPDDTCT 307
Query: 170 GIRGSEQLMAPEVFQ-RLKYEGTPVDMWSLGIMMFEFFNNSNKPAFPWK----IAKIDDV 224
+GS PE+ + G VD+WS G+ ++ N +P++ ++++
Sbjct: 308 TGQGSPAFQPPEIANGHETFAGFKVDIWSSGVTLY----NLATGQYPFEGDNIYRLLENI 363
Query: 225 AFEAYTKNPTTLNISID---LCMKLLSVDVKQRLSIQDVINDSFFQ 267
+ + D L + +L D +RLS+Q++ +D++F+
Sbjct: 364 GRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWFR 409
>Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1
Length = 716
Score = 69.7 bits (169), Expect = 5e-12
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 23/199 (11%)
Query: 25 QGTTCEV-EIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNK 83
QG T V + +K G +A+K F + + +EV V+E+E+L+KLNH+ I++ +
Sbjct: 17 QGATASVYKARNKKSGELVAVKVFNTTS-YLRPREVQVREFEVLRKLNHQNIVKLFAVEE 75
Query: 84 ----RKHTITFPYYSYTVLYLMKMSM-----LPTFEERALWFCQICEGIAYLHSHNIVHR 134
R+ + Y S L + S LP E + C + G+ +L + IVHR
Sbjct: 76 TGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRC-VVAGMNHLRENGIVHR 134
Query: 135 DLKLENIM---VDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRL----- 186
D+K NIM +E K+ DFG+A ++ + E + G+E+ + P++++R
Sbjct: 135 DIKPGNIMRLVGEEGQSIYKLTDFGAAREL-DDDEKFVSVYGTEEYLHPDMYERAVLRKP 193
Query: 187 --KYEGTPVDMWSLGIMMF 203
K G VD+WS+G+ ++
Sbjct: 194 QQKAFGVTVDLWSIGVTLY 212
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 69.7 bits (169), Expect = 5e-12
Identities = 47/157 (29%), Positives = 81/157 (50%), Gaps = 10/157 (6%)
Query: 117 CQIC-EGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSE 175
C+ C + + +LHS+ ++HRD+K +NI++ ++K+ DFG + P + + G+
Sbjct: 370 CRECLQALEFLHSNQVIHRDIKSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTP 428
Query: 176 QLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNKPAF----PWKIAKIDDVAFEAYTK 231
MAPEV R Y G VD+WSLGIM E +P + P + + +
Sbjct: 429 YWMAPEVVTRKAY-GPKVDIWSLGIMAIEMI--EGEPPYLNENPLRALYLIATNGTPELQ 485
Query: 232 NPTTLN-ISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
NP L+ I D + L +DV++R S ++++ F +
Sbjct: 486 NPEKLSAIFRDFLNRCLDMDVEKRGSAKELLQHQFLK 522
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 69.7 bits (169), Expect = 5e-12
Identities = 63/243 (25%), Positives = 109/243 (43%), Gaps = 16/243 (6%)
Query: 37 SDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITF-----P 91
S+ ++A+K+ D + + + +E L K L HK I++ L I P
Sbjct: 701 SNQVRIAIKEIPERD--SRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVP 758
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKLENIMVDESLCNI 150
S + L K L E+ ++ QI EG+ YLH + IVHRD+K +N++++ +
Sbjct: 759 GGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVL 818
Query: 151 KIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQR-LKYEGTPVDMWSLGIMMFEFFNNS 209
KI DFG++ + G+ Q MAPE+ + + G D+WSLG + E +
Sbjct: 819 KISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEM--AT 876
Query: 210 NKPAF----PWKIAKIDDVAFEAYTKNPTTLNISID-LCMKLLSVDVKQRLSIQDVINDS 264
KP F + A F+ + + P +++ +K D +R D++ D
Sbjct: 877 GKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDE 936
Query: 265 FFQ 267
F +
Sbjct: 937 FLK 939
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 69.7 bits (169), Expect = 5e-12
Identities = 54/156 (34%), Positives = 83/156 (52%), Gaps = 20/156 (12%)
Query: 110 EERALWF-CQICEGIAYLHSH-NIVHRDLKLENIMVDESLCNIKIIDFGSAVDVGPNKEA 167
E+RA ++ +I + YLHS N+V+RDLKLEN+M+D+ +IKI DFG + +
Sbjct: 247 EDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKD-GHIKITDFGLCKEGIKDGAT 305
Query: 168 CHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFE-------FFNNSNKPAFPWKIAK 220
G+ + +APEV + Y G VD W LG++M+E F+N ++ F ++
Sbjct: 306 MKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLF--ELIL 362
Query: 221 IDDVAFEAYTKNPTTLNISI-DLCMKLLSVDVKQRL 255
++++ F P TL L LL D KQRL
Sbjct: 363 MEEIRF------PRTLGPEAKSLLSGLLKKDPKQRL 392
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 69.7 bits (169), Expect = 5e-12
Identities = 54/187 (28%), Positives = 93/187 (48%), Gaps = 20/187 (10%)
Query: 99 YLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSA 158
YL + L E R++ + E +++LH++NIVHRDLK ENI++D+++ I++ DFG +
Sbjct: 118 YLTEKVALSEKETRSI-MRSLLEAVSFLHANNIVHRDLKPENILLDDNM-QIRLSDFGFS 175
Query: 159 VDVGPNKEACHGIRGSEQLMAPEVFQRLKYE-----GTPVDMWSLGIMMFEFFNNSNKPA 213
+ P E + G+ +APE+ + E G VD+W+ G+++F S P
Sbjct: 176 CHLEPG-EKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGS--PP 232
Query: 214 FPWKIAKI--------DDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSF 265
F W +I F + + + + DL +LL VD + RL+ + + F
Sbjct: 233 F-WHRRQILMLRMIMEGQYQFSSPEWDDRSSTVK-DLISRLLQVDPEARLTAEQALQHPF 290
Query: 266 FQENHNS 272
F+ S
Sbjct: 291 FERCEGS 297
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 69.7 bits (169), Expect = 5e-12
Identities = 53/192 (27%), Positives = 93/192 (47%), Gaps = 9/192 (4%)
Query: 25 QGTTCEVEIVSKSDGSKL----ALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIE--- 77
QG+ +V +V K GS A+K + L + E ++L ++NH I++
Sbjct: 67 QGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHY 126
Query: 78 ALDCNKRKHTITFPYYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLK 137
A + + I + + ++ T E+ + ++ + +LHS I++RDLK
Sbjct: 127 AFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLK 186
Query: 138 LENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWS 197
ENI++DE +IKI DFG + + + + + G+ + MAPEV R + + D WS
Sbjct: 187 PENILLDEE-GHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQS-ADWWS 244
Query: 198 LGIMMFEFFNNS 209
G++MFE S
Sbjct: 245 FGVLMFEMLTGS 256
Score = 58.9 bits (141), Expect = 8e-09
Identities = 48/155 (30%), Positives = 75/155 (47%), Gaps = 11/155 (7%)
Query: 117 CQICEGIAYLHSHNIVHRDLKLENIMV-DESLC--NIKIIDFGSAVDVGPNKEACHGIRG 173
C I + + YLHS +VHRDLK NI+ DES +I++ DFG A +
Sbjct: 514 CTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY 573
Query: 174 SEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFE 227
+ +APEV +R Y+ D+WSLGI+++ F N +A+I +
Sbjct: 574 TANFVAPEVLKRQGYDAA-CDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYA 632
Query: 228 AYTKNPTTL-NISIDLCMKLLSVDVKQRLSIQDVI 261
N ++ + + D+ K+L VD QRL+ V+
Sbjct: 633 LSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVL 667
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 69.7 bits (169), Expect = 5e-12
Identities = 68/262 (25%), Positives = 117/262 (43%), Gaps = 35/262 (13%)
Query: 33 IVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY 92
+V K A K F+++ KE +E ++ L+H +++ +D + K I
Sbjct: 559 LVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVL 616
Query: 93 YSYTVLYLMKMSMLPTFE----ERALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESL 147
+ L + + FE E + QI EG+ Y+H IVH DLK ENIM V+++
Sbjct: 617 EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTG 676
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYE--GTPVDMWSLGIMMFEF 205
IK+IDFG A + N + + G+ + +APEV + YE G DMWS+G++ +
Sbjct: 677 TRIKLIDFGLARRL-ENAGSLKVLFGTPEFVAPEV---INYEPIGYATDMWSIGVICYIL 732
Query: 206 FNN-------------SNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVK 252
+ +N + W DD AF+ + + + D LL D+K
Sbjct: 733 VSGLSPFMGDNDNETLANVTSATW---DFDDEAFDEISDD------AKDFISNLLKKDMK 783
Query: 253 QRLSIQDVINDSFFQENHNSVD 274
RL + + ++ +++
Sbjct: 784 NRLDCTQCLQHPWLMKDTKNME 805
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 69.7 bits (169), Expect = 5e-12
Identities = 68/262 (25%), Positives = 117/262 (43%), Gaps = 35/262 (13%)
Query: 33 IVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY 92
+V K A K F+++ KE +E ++ L+H +++ +D + K I
Sbjct: 1412 LVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVL 1469
Query: 93 YSYTVLYLMKMSMLPTFE----ERALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESL 147
+ L + + FE E + QI EG+ Y+H IVH DLK ENIM V+++
Sbjct: 1470 EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTG 1529
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYE--GTPVDMWSLGIMMFEF 205
IK+IDFG A + N + + G+ + +APEV + YE G DMWS+G++ +
Sbjct: 1530 TRIKLIDFGLARRL-ENAGSLKVLFGTPEFVAPEV---INYEPIGYATDMWSIGVICYIL 1585
Query: 206 FNN-------------SNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVK 252
+ +N + W DD AF+ + + + D LL D+K
Sbjct: 1586 VSGLSPFMGDNDNETLANVTSATW---DFDDEAFDEISDD------AKDFISNLLKKDMK 1636
Query: 253 QRLSIQDVINDSFFQENHNSVD 274
RL + + ++ +++
Sbjct: 1637 NRLDCTQCLQHPWLMKDTKNME 1658
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 69.7 bits (169), Expect = 5e-12
Identities = 68/262 (25%), Positives = 117/262 (43%), Gaps = 35/262 (13%)
Query: 33 IVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY 92
+V K A K F+++ KE +E ++ L+H +++ +D + K I
Sbjct: 1481 LVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVL 1538
Query: 93 YSYTVLYLMKMSMLPTFE----ERALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESL 147
+ L + + FE E + QI EG+ Y+H IVH DLK ENIM V+++
Sbjct: 1539 EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYE--GTPVDMWSLGIMMFEF 205
IK+IDFG A + N + + G+ + +APEV + YE G DMWS+G++ +
Sbjct: 1599 TRIKLIDFGLARRL-ENAGSLKVLFGTPEFVAPEV---INYEPIGYATDMWSIGVICYIL 1654
Query: 206 FNN-------------SNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVK 252
+ +N + W DD AF+ + + + D LL D+K
Sbjct: 1655 VSGLSPFMGDNDNETLANVTSATW---DFDDEAFDEISDD------AKDFISNLLKKDMK 1705
Query: 253 QRLSIQDVINDSFFQENHNSVD 274
RL + + ++ +++
Sbjct: 1706 NRLDCTQCLQHPWLMKDTKNME 1727
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 69.7 bits (169), Expect = 5e-12
Identities = 68/262 (25%), Positives = 117/262 (43%), Gaps = 35/262 (13%)
Query: 33 IVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPY 92
+V K A K F+++ KE +E ++ L+H +++ +D + K I
Sbjct: 559 LVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVL 616
Query: 93 YSYTVLYLMKMSMLPTFE----ERALWFCQICEGIAYLHSHNIVHRDLKLENIM-VDESL 147
+ L + + FE E + QI EG+ Y+H IVH DLK ENIM V+++
Sbjct: 617 EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTG 676
Query: 148 CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYE--GTPVDMWSLGIMMFEF 205
IK+IDFG A + N + + G+ + +APEV + YE G DMWS+G++ +
Sbjct: 677 TRIKLIDFGLARRL-ENAGSLKVLFGTPEFVAPEV---INYEPIGYATDMWSIGVICYIL 732
Query: 206 FNN-------------SNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVK 252
+ +N + W DD AF+ + + + D LL D+K
Sbjct: 733 VSGLSPFMGDNDNETLANVTSATW---DFDDEAFDEISDD------AKDFISNLLKKDMK 783
Query: 253 QRLSIQDVINDSFFQENHNSVD 274
RL + + ++ +++
Sbjct: 784 NRLDCTQCLQHPWLMKDTKNME 805
>At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 736
Score = 69.7 bits (169), Expect = 5e-12
Identities = 54/185 (29%), Positives = 90/185 (48%), Gaps = 12/185 (6%)
Query: 38 DGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALD--CNKRKHTITFPYYSY 95
+GS +A+K + D + C KE ++KKL H ++ + C + K I Y
Sbjct: 488 NGSDVAIKVYFDGDYNAMTLTECKKEINIMKKLRHPNVLLFMGAVCTEEKSAIIMEYMPR 547
Query: 96 TVLY-LMKMSMLPTFEERALWFC-QICEGIAYLHSHN--IVHRDLKLENIMVDESLCNIK 151
L+ ++ + P ++R L + G+ YLH N IVHRDLK N++VD++ N+K
Sbjct: 548 GSLFKILHNTNQPLDKKRRLRMALDVARGMNYLHRRNPPIVHRDLKSSNLLVDKN-WNVK 606
Query: 152 IIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEFFNNSNK 211
+ DFG + + +G+ Q MAPEV R + D++S G++++E
Sbjct: 607 VGDFGLSKWKNATFLSTKSGKGTPQWMAPEVL-RSEPSNEKCDVFSFGVILWELMTT--- 662
Query: 212 PAFPW 216
PW
Sbjct: 663 -LVPW 666
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 69.7 bits (169), Expect = 5e-12
Identities = 62/262 (23%), Positives = 118/262 (44%), Gaps = 22/262 (8%)
Query: 22 RLIQGTTCEVEIVSKSDGSKLALKKF--RSWDLHNHHKEVCVKEYELLKKLNHK---CII 76
RL G+ +V + + +L K + + + + ++E + +++L H I
Sbjct: 30 RLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEPRIIREIDAMRRLRHHPNILKI 89
Query: 77 EALDCNKRKHTITFPYYSYTVLY--LMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHR 134
+ K K + S L+ +++ LP R +F Q+ + + H + HR
Sbjct: 90 HEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARR-YFQQLASALRFSHQDGVAHR 148
Query: 135 DLKLENIMVDESLCNIKIIDFG-SAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPV 193
D+K +N+++DE N+K+ DFG SA+ H G+ APEV R Y+G
Sbjct: 149 DVKPQNLLLDEQ-GNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEVISRRGYDGAKA 207
Query: 194 DMWSLGIMMFEF------FNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLL 247
D WS G+++F F++SN A KI + D F ++ + ++L
Sbjct: 208 DAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHR-RDYRFPSWISKQAK-----SIIYQML 261
Query: 248 SVDVKQRLSIQDVINDSFFQEN 269
+ R+SI+ V+ ++F+++
Sbjct: 262 DPNPVTRMSIETVMKTNWFKKS 283
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 69.7 bits (169), Expect = 5e-12
Identities = 67/288 (23%), Positives = 124/288 (42%), Gaps = 45/288 (15%)
Query: 26 GTTCEVEIVSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDC--NK 83
G C ++ +A+KK + + + ++E +LL+ ++H+ I+ D
Sbjct: 75 GIVCSA--MNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPP 132
Query: 84 RKHTITFPYYSY----TVLYLMKMSMLPTFEERALWFC-QICEGIAYLHSHNIVHRDLKL 138
++ Y +Y T L+ + S EE +F QI G+ Y+HS N++HRDLK
Sbjct: 133 LRNAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKP 192
Query: 139 ENIMVDESLCNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSL 198
N++++ + C++KI DFG A V + + APE+ +D+WS+
Sbjct: 193 SNLLLNAN-CDLKICDFGLA-RVTSESDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSV 250
Query: 199 GIMMFEFFNNSNKPAFPWK-------------------------------IAKIDDVAFE 227
G + E + KP FP + I ++ +
Sbjct: 251 GCIFMELMD--RKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNENAKRYIRQLPPYPRQ 308
Query: 228 AYT-KNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQENHNSVD 274
+ T K PT ++IDL K+L+ D ++R+++ D + + H+ D
Sbjct: 309 SITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHPYLNSLHDISD 356
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 69.7 bits (169), Expect = 5e-12
Identities = 60/249 (24%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 37 SDGSKLALKKFRSWDLHNHH--KEVCVKEYELLKKLNHKCIIEALD--CNKRKHTITFPY 92
S G +A+K + + E +E +++ L H ++E + K+K Y
Sbjct: 36 STGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLRHPNVVELREVMATKKKIFFVMEY 95
Query: 93 YSYTVLYLM--KMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNI 150
+ L+ M + LP R +F Q+ + + HS + HRD+K EN+++D ++
Sbjct: 96 VNGGELFEMIDRDGKLPEDLARK-YFQQLISAVDFCHSRGVFHRDIKPENLLLDGE-GDL 153
Query: 151 KIIDFGSAVDV---------GPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIM 201
K+ DFG + + G + + H G+ +APEV + Y+G D+WS GI+
Sbjct: 154 KVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVLRNKGYDGAMADIWSCGIV 213
Query: 202 MFEFFNNSNKPAFPWKIAKIDDVAFEAYTKNPTTLNI-SIDLCMKLLSVDVKQRLSIQDV 260
++ P + + F+A + P ++ S +L +LL D +QR+S+ ++
Sbjct: 214 LYALLAGF-LPFIDENVMTLYTKIFKAECEFPPWFSLESKELLSRLLVPDPEQRISMSEI 272
Query: 261 INDSFFQEN 269
+F++N
Sbjct: 273 KMIPWFRKN 281
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 69.7 bits (169), Expect = 5e-12
Identities = 68/273 (24%), Positives = 116/273 (41%), Gaps = 47/273 (17%)
Query: 39 GSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALD-----CNKRKHTI--TFP 91
G K+A+KK + H ++E +LL+ L H I+E C K I F
Sbjct: 39 GGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHPDIVEIKHIMLPPCRKEFKDIYVVFE 98
Query: 92 YYSYTVLYLMKMSMLPTFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCNIK 151
+ +++K++ T + + Q+ G+ ++HS ++ HRDLK +NI+ + C IK
Sbjct: 99 LMESDLHHVLKVNDDLTPQHHQFFLYQLLRGLKFMHSAHVFHRDLKPKNILANAD-CKIK 157
Query: 152 IIDFGSA---VDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTP-VDMWSLGIMMFEFFN 207
I D G A P+ + APE+ TP +DMWS+G + E
Sbjct: 158 ICDLGLARVSFTDSPSAVFWTDYVATRWYRAPELCGSFYSNYTPAIDMWSVGCIFAEML- 216
Query: 208 NSNKPAFPWK--IAKIDDVAFEAYTKNPTTLN---------------------------- 237
+ KP FP K + +++ V T +P TL+
Sbjct: 217 -TGKPLFPGKNVVHQLELVTDLLGTPSPITLSRIRNEKARKYLGNMRRKDPVPFTHKFPN 275
Query: 238 ---ISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+++ L +L++ D K R S ++ + D +FQ
Sbjct: 276 IDPVALKLLQRLIAFDPKDRPSAEEALADPYFQ 308
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 69.7 bits (169), Expect = 5e-12
Identities = 50/181 (27%), Positives = 87/181 (47%), Gaps = 18/181 (9%)
Query: 34 VSKSDGSKLALKKFRSWDLHNHHKEVCVKEYELLKKLNHKCIIEALDCNKRKHTITFPYY 93
V KS G + A K + L + +E + +KL+H I+ D + ++ Y
Sbjct: 32 VQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEEN------Y 85
Query: 94 SYTVLYLMKMSML-------PTFEERALWFC--QICEGIAYLHSHNIVHRDLKLENIMVD 144
Y V L+ L + E C QI E + + H + +VHRDLK EN+++
Sbjct: 86 HYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLA 145
Query: 145 ESL--CNIKIIDFGSAVDVGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMM 202
+K+ DFG A++V + +A G G+ ++PEV ++ Y G VD+W+ G+++
Sbjct: 146 SKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPY-GKSVDIWACGVIL 204
Query: 203 F 203
+
Sbjct: 205 Y 205
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 69.7 bits (169), Expect = 5e-12
Identities = 65/233 (27%), Positives = 103/233 (43%), Gaps = 28/233 (12%)
Query: 58 EVCVKEYELLKKLNHKCII-EALDCNKRKHTITFPYY-SYTVL--------YLMKMSMLP 107
EV +K+ L ++ + II E L + KH Y SY V YL S+
Sbjct: 455 EVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTD 514
Query: 108 TFEERALWFCQIC-------EGIAYLHSHNIVHRDLKLENIMVDESLCNIKIIDFGSAVD 160
E + QI + + +LH++ ++HRD+K +NI++ ++K+ DFG
Sbjct: 515 VVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLD-GSVKLTDFGFCAQ 573
Query: 161 VGPNKEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMFEF------FNNSNKPAF 214
+ P + + G+ MAPEV R +Y G VD+WSLGIM E + N N
Sbjct: 574 ISPEQSKRTTMVGTPYWMAPEVVTRKQY-GPKVDLWSLGIMAIEMVEGEPPYLNENPLKA 632
Query: 215 PWKIAKIDDVAFEAYTKNPTTLNISIDLCMKLLSVDVKQRLSIQDVINDSFFQ 267
+ IA + K + +D C L V+V +R S D++ F +
Sbjct: 633 LYLIATNGKPEIKEKDKLSSAFQDFLDQC---LEVEVDRRASALDLLKHPFLK 682
>7290629 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 359
Score = 69.7 bits (169), Expect = 5e-12
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 25/200 (12%)
Query: 108 TFEERALWFCQICEGIAYLHSHNIVHRDLKLENIMVDESLCN--IKIIDFGSAVDVGPN- 164
T E A +IC + YLHS +I HRDLK EN++ + N +K+ DFG A + +
Sbjct: 115 TEREAAQIMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSY 174
Query: 165 --KEACHGIRGSEQLMAPEVFQRLKYEGTPVDMWSLGIMMF-------EFFNNSNKPAFP 215
+ C+ + +APEV KY+ + D+WSLG++M+ F++N P
Sbjct: 175 TLQTPCY----TPYYVAPEVLGPEKYDKS-CDIWSLGVVMYIIMCGFPPFYSNHGLAISP 229
Query: 216 WKIAKIDDVAFEAYTKNPTTLNIS---IDLCMKLLSVDVKQRLSIQDVINDSFFQENHNS 272
+I ++ +P N+S DL +L+VD +RL IQDVI++ + + +N+
Sbjct: 230 GMKNRIRTGQYD--FPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQ-YNA 286
Query: 273 VDGVSAHARTKRILERSQTT 292
V T R+L+ ++ T
Sbjct: 287 VP--QTPLCTGRMLKEAEET 304
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,165,073
Number of Sequences: 60738
Number of extensions: 739879
Number of successful extensions: 5315
Number of sequences better than 1.0e-05: 1181
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 1168
Number of HSP's that attempted gapping in prelim test: 3776
Number of HSP's gapped (non-prelim): 1359
length of query: 292
length of database: 30,389,216
effective HSP length: 105
effective length of query: 187
effective length of database: 24,011,726
effective search space: 4490192762
effective search space used: 4490192762
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)