ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0619 good K KOG4134 Transcription DNA-dependent RNA polymerase I
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0619 208858 209718 287
(287 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR340c [K] KOG4134 DNA-dependent RNA polymerase I 351 6e-97
SPBC3B9.07c [K] KOG4134 DNA-dependent RNA polymerase I 112 6e-25
Hs20539462 [K] KOG4134 DNA-dependent RNA polymerase I 61 2e-09
7297185 [K] KOG4134 DNA-dependent RNA polymerase I 55 9e-08
>YOR340c [K] KOG4134 DNA-dependent RNA polymerase I
Length = 326
Score = 351 bits (901), Expect = 6e-97
Identities = 176/309 (56%), Positives = 225/309 (71%), Gaps = 33/309 (10%)
Query: 1 MKRSSEEVKALRLIKRFKKTSKNPIDEEDGCSKCIVRVPVFMYVSLAPIYQQLPKEGIMR 60
+KR++E + R IK+ KK NPIDE++G S CIVRVP+ +YVSLAP+Y + P +G+M+
Sbjct: 4 VKRANENRETARFIKKHKKQVTNPIDEKNGTSNCIVRVPIALYVSLAPMYLENPLQGVMK 63
Query: 61 QHLNGMVMKYNADVGGVILGYENLSILGEEPTEED---EKLMKLTADTPFAFTWCNVEVI 117
QHLN +VMKYN VGGV+LGYE L IL +P ++ EKL+K+T DTPF FTWC+V +
Sbjct: 64 QHLNPLVMKYNNKVGGVVLGYEGLKILDADPLSKEDTSEKLIKITPDTPFGFTWCHVNLY 123
Query: 118 VWQPQVGDTIEGWIFIQSASHIGLLIHDAFNASIKKNNIPNDWTFIHNEETTE------- 170
VWQPQVGD +EG+IFIQSASHIGLLIHDAFNASIKKNNIP DWTF+HN+ +
Sbjct: 124 VWQPQVGDVLEGYIFIQSASHIGLLIHDAFNASIKKNNIPVDWTFVHNDVEEDADVINTD 183
Query: 171 --NGQDSTDDRK---------------FQSLGHWVDGNGQQLGGKLKFKVKNVYTTGRMV 213
NG ++ +D K +SLGHWVD NG+ + GKL+F V+NV+TTGR+V
Sbjct: 184 ENNGNNNNEDNKDSNGGSNSLGKFSFGNRSLGHWVDSNGEPIDGKLRFTVRNVHTTGRVV 243
Query: 214 SLEGTLLDDS------ARGSHSEAENLPVVSNKKIVFDDEVSKENTDSHKELELSVVKED 267
S++GTL+ D+ S S+AE+LP+VSNKKIVFDDEVS EN +SHKEL+L VKED
Sbjct: 244 SVDGTLISDADEEGNGYNSSRSQAESLPIVSNKKIVFDDEVSIENKESHKELDLPEVKED 303
Query: 268 NGDEIIYEK 276
NG EI+YE+
Sbjct: 304 NGSEIVYEE 312
>SPBC3B9.07c [K] KOG4134 DNA-dependent RNA polymerase I
Length = 173
Score = 112 bits (280), Expect = 6e-25
Identities = 64/180 (35%), Positives = 100/180 (55%), Gaps = 20/180 (11%)
Query: 40 VFMYVSLAPIYQQLPKEGIMRQHLNGMVMKYNADVGGVILGYENLSILGEEPTEEDEKLM 99
V +Y+S+AP + + P I ++H++ M++ + G++L Y+N+ L EK
Sbjct: 11 VDLYLSIAPGHSRDPLNAI-QEHMDSMILSKLPRINGIVLAYDNIRFL--------EKSA 61
Query: 100 KLTADTPFAFTWCNVEVIVWQPQVGDTIEGWIFIQSASHIGLLIHDAFNASIKKNNIPND 159
K+ D+PF+F W V+V+V+ P+ GD +EG I + S SHIGLLI FNASI + +IP D
Sbjct: 62 KVMYDSPFSFIWVRVDVLVFSPKKGDCLEGKINLVSPSHIGLLILGIFNASIPRKSIPKD 121
Query: 160 WTFIHNEETTENGQDSTDDRKFQSLGHWVDGNGQQLGGKLKFKVKNVYTTGRMVSLEGTL 219
W FI + T E G+ T+ DGN + G L+F V + + ++GTL
Sbjct: 122 WIFIEPDTTEEQGRWKTN-----------DGNILEPGKDLEFVVDGIQREAGLTMVQGTL 170
>Hs20539462 [K] KOG4134 DNA-dependent RNA polymerase I
Length = 338
Score = 60.8 bits (146), Expect = 2e-09
Identities = 36/121 (29%), Positives = 66/121 (53%), Gaps = 11/121 (9%)
Query: 34 CIVRVPVFMYVSLAPIYQQLPKEGIMRQHLNGMVMKYNADVGGVILGYENLSILGE-EPT 92
C+V P +++L+P Y + GI R+ L+ +++Y+ + GV + Y+N+ ++GE
Sbjct: 47 CLVAGPHQRHIALSPRYLNRKRTGI-REQLDAELLRYSESLLGVPIAYDNIKVVGELGDI 105
Query: 93 EEDEKLMKLTADTPFAFTWCNVEVIVWQPQVGDTIEGWIFIQSASHIGLLIHDAFNASIK 152
+D+ + L + F +++ P+ G + G + S+SHIG L+H FNASI
Sbjct: 106 YDDQGHIHLNIEADF---------VIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNASIP 156
Query: 153 K 153
K
Sbjct: 157 K 157
>7297185 [K] KOG4134 DNA-dependent RNA polymerase I
Length = 253
Score = 55.5 bits (132), Expect = 9e-08
Identities = 57/262 (21%), Positives = 104/262 (38%), Gaps = 57/262 (21%)
Query: 12 RLIKRFKKTSKNPIDEEDGCSKCIVRVPVFMYVSLAPIYQQLPKEGIMRQHLNGMVMKYN 71
+ IK K +N + C +CI M++++ P K + + V Y+
Sbjct: 7 KYIKFSVKELENYASSPESCVRCIT---TDMHLAMGPYGMANFKHALHELLIRTKVGFYD 63
Query: 72 ADVGGVILGYENLSILGEEPTEEDEKLMKLTADTPFAFTWCNVEVIVWQPQVGDTIEGWI 131
+ + G++LG +N+ +LG+ L AD P N + V++P+ G + G +
Sbjct: 64 SGLDGIVLGIKNIKVLGQTAG--------LRADDPTMHLVINADFYVFRPKAGAILSGVV 115
Query: 132 FIQSASHIGLLIHDAFNASIKKNNIPNDWTFIHNEETTENGQDSTDDRKFQSLGHWVDGN 191
S H+ +I+ FN SI+ N + + +D D+
Sbjct: 116 RHISRHHVSAVIYRVFNTSIRFTN------------QSASREDIAMDQ------------ 151
Query: 192 GQQLGGKLKFKVKNVYTTGRMVSLEGTLLDDSARGSHSEAENLPVVSNKKIVF------D 245
++K ++KN + M +EG LL EN NK I F +
Sbjct: 152 ------EIKIRIKNFDISNLMPYIEGELL----------LENGEAPKNKSIKFGSPPPEE 195
Query: 246 DEVSKENTDSHKELELSVVKED 267
EV KE+ D + ++ +K++
Sbjct: 196 KEVKKEDPDEMLDALITEIKKE 217
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,513,612
Number of Sequences: 60738
Number of extensions: 782219
Number of successful extensions: 1554
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1543
Number of HSP's gapped (non-prelim): 5
length of query: 287
length of database: 30,389,216
effective HSP length: 105
effective length of query: 182
effective length of database: 24,011,726
effective search space: 4370134132
effective search space used: 4370134132
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)